Bench Blasting Design for Optimum Recovery of Blocks in Dimension Stone Quarries: A Case Study of Crushed Rock Industry, Supare-Nigeria

Dimension stone quarry is believed to be type of mining operation that always result to low recovery since what is expected from the extracting operation is a cubical block with no fracture. It is noticed that majority of the damage in the natural blocks are always from poor extraction method. In aggregate quarry, series of work have been done on powder factor that gives economical blasting. In this research work, breaking factor is used in place of powder factor since breaking is required not powder. The aim of this research work is to establish a standard breaking factor for bench blasting in dimension quarries that will improve recovery.Two cases were considered. In case 1, gun powder is used for basal cutting. Of the seven patterns considered, pattern3 gives highest recovery (70%) with breaking factor of 23.15g/m3 (i.e. 5kg of Gun powder for (6 by 6 by 6) m bench design). In the case 2, dynacord is used for basal cutting. Of the four patterns considered, pattern 2 gives highest recovery (55%) with breaking factor of 15g/m3 ( i.e. 3.24kg of explosive for (6 by 6 by 6) m bench design.Keywords: Extracting, powder factor, aggregate, recovery, breaking facto

Ectopic (tubal) Molar Gestation: Report Of Two Cases

Ectopicmolar gestation is a rare event. Itsmalignant potential is similar to that of an intrauterine molar pregnancy. To document two cases of tubalmolar gestations seen over a 10-year period. Case series. Two young Nigerian undergraduates presented with features of ruptured tubal pregnancy. They had total salpingectomy and histopathological analysis of the tubal specimens revealed complete hydatidiform mole.HCGlevel normalized in both caseswithin threeweeks of treatment. Ectopic molar gestation does occur occasional in our setting. It is pertinent that clinicians in this part of the world be aware of this and to take routine histological examination of tubal specimens in ectopic pregnancy very seriously in order to diagnosed cases of ectopic molar gestations early and mount appropriate post treatment surveillance. Keywords: ectopic,Tubal,MolarGestation. Nigerian Journal of Clinical Practice Vol. 11 (4) 2008: pp. 392-39

Chemical equivalence assessment of three brands of carbamazepine tablets and their anticonvulsant outcome on electrically-induced seizures in chicks

Assay for content of active ingredients is a critical test of drug quality; failure to meet up the standard for content of active ingredients will result to sub therapeutic quantities. Three brands (A, B and C) of carbamazepine were assayed to determine their chemical equivalence as well as their anticonvulsant activities. This was aimed at determining the possible relation between the chemical equivalence of the brands and their anticonvulsant outcomes. The brands were randomly selected from Community Pharmacies in Zaria, Kaduna State, and assayed for chemical equivalence to establish weight uniformity and identity; percentage content of active ingredients, using UV spectrophotometric analysis. Similarly all the brands were evaluated for anticonvulsant activity using maximal electroshock seizure model in chicks at doses of 20, 10 and 5 mg/kg. All the brands passed weight uniformity test as none of the tablets deviated from the mean by more than 7.5%. Similarly, their melting points were found to conform to standard average melting point (191oC) according to B.P. official monograph. However, the content of the active ingredients for Brands B and C did not conform to official standard of 95-105% while brand A conformed. Thus, the percentage contents for brands A, B and C were 99.49%, 76.02% and 87.59% respectively. Also, all the brands at the tested doses offered protection against seizures, ranging from 70-100%; but Brand C at 5 mg/kg offered only 40% quantal protection. The three brands of carbamazepine tablets were not chemically equivalent and their chemical equivalence indices could not be said to be the determinant of anticonvulsant effect.Key words: carbamazepine, anticonvulsant and chemical equivalenc

Bioassay guided isolation of active phytochemicals from hyphaenethebaica (L) mart fruit pulp methanol extract responsible for hypoglycaemic activity

Active phytochemical responsible for hypoglycaemicactivily from Hyphaenethebaica (L) Mart were separated using Bioassay guided fractionation. Methodology: Five hundred grams (500g) methanolic fruit extract of H. thebaicawas suspended in water, filtered and sequentially partitioned with hexane, chloroform, ethyl acetate and n-butanol. The n-butanol fraction was subjected to column chromatography, sub-fraction A, B, C, D, E, F and G were obtained. Further separation using preparative TLC of fraction C afforded sub-fraction C, C, and 1 2 C. Finally, C gaveRF value. Diabetes was induced to albino rats of both sexes by intra muscular 3 1 injection of 120mg/kg Alloxan monohydrate. The diabetic rats were grouped according to the number of fractions and sub-fractions with 3 rats each. Each fraction was tested for hypoglycaemic activity. The one with highest activity was used for next study and phytochemical constituents analysed. Results: The phytochemical screening of70% methanol extract of Hyphaenethebaicafruit pulp were reported to contain saponins, tannins, terpenoids, cardiac glycosides with the exception of alkaloid, combined anthraquinone, free anthraquinone and soluble starch. The n-butanol portion showed hypoglycaemic activity (66.37±1.03% reduction) compared to other fractions at 400mg/kg. The n-butanol portion similarly contained phytochemicals found in crude extract except forsaponins which is absent. The column fraction C of the n-butanol portion has maximum reduction (45.33± 2.80%) of fasting blood glucose of diabetic rats at a lower dose of 200 mg/kg. Sub-fraction C has more hypoglycaemic activity of 1 60.50%while phytochemical evaluation showed the presence of flavonoids. Conclusion: Flavonoids may be responsible for the observed hypoglyceamic effect of H. thebaicsfruit pulp

Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at √s=8TeV

The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fb−1of data collected in proton–proton collisions at √s=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV

Measurements of fiducial and differential cross sections for Higgs boson production in the diphoton decay channel at s√=8 TeV with ATLAS

Measurements of fiducial and differential cross sections are presented for Higgs boson production in proton-proton collisions at a centre-of-mass energy of s√=8 TeV. The analysis is performed in the H → γγ decay channel using 20.3 fb−1 of data recorded by the ATLAS experiment at the CERN Large Hadron Collider. The signal is extracted using a fit to the diphoton invariant mass spectrum assuming that the width of the resonance is much smaller than the experimental resolution. The signal yields are corrected for the effects of detector inefficiency and resolution. The pp → H → γγ fiducial cross section is measured to be 43.2 ±9.4(stat.) − 2.9 + 3.2 (syst.) ±1.2(lumi)fb for a Higgs boson of mass 125.4GeV decaying to two isolated photons that have transverse momentum greater than 35% and 25% of the diphoton invariant mass and each with absolute pseudorapidity less than 2.37. Four additional fiducial cross sections and two cross-section limits are presented in phase space regions that test the theoretical modelling of different Higgs boson production mechanisms, or are sensitive to physics beyond the Standard Model. Differential cross sections are also presented, as a function of variables related to the diphoton kinematics and the jet activity produced in the Higgs boson events. The observed spectra are statistically limited but broadly in line with the theoretical expectations

Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at s√=8 TeV with the ATLAS detector

The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy s√=8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb−1. No significant excess above the Standard Model expectation is observed. Limits are set on supersymmetric particle masses for various supersymmetric models. Depending on the model, the search excludes gluino masses up to 1.32 TeV and squark masses up to 840 GeV. Limits are also set on the parameters of a minimal universal extra dimension model, excluding a compactification radius of 1/R c = 950 GeV for a cut-off scale times radius (ΛR c) of approximately 30

Evidence for the Higgs-boson Yukawa coupling to tau leptons with the ATLAS detector

Results of a search for H → τ τ decays are presented, based on the full set of proton-proton collision data recorded by the ATLAS experiment at the LHC during 2011 and 2012. The data correspond to integrated luminosities of 4.5 fb−1 and 20.3 fb−1 at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV respectively. All combinations of leptonic (τ → `νν¯ with ` = e, µ) and hadronic (τ → hadrons ν) tau decays are considered. An excess of events over the expected background from other Standard Model processes is found with an observed (expected) significance of 4.5 (3.4) standard deviations. This excess provides evidence for the direct coupling of the recently discovered Higgs boson to fermions. The measured signal strength, normalised to the Standard Model expectation, of µ = 1.43 +0.43 −0.37 is consistent with the predicted Yukawa coupling strength in the Standard Model

Search for squarks and gluinos with the ATLAS detector in final states with jets and missing transverse momentum using √s=8 TeV proton-proton collision data

A search for squarks and gluinos in final states containing high-p T jets, missing transverse momentum and no electrons or muons is presented. The data were recorded in 2012 by the ATLAS experiment in s√=8 TeV proton-proton collisions at the Large Hadron Collider, with a total integrated luminosity of 20.3 fb−1. Results are interpreted in a variety of simplified and specific supersymmetry-breaking models assuming that R-parity is conserved and that the lightest neutralino is the lightest supersymmetric particle. An exclusion limit at the 95% confidence level on the mass of the gluino is set at 1330 GeV for a simplified model incorporating only a gluino and the lightest neutralino. For a simplified model involving the strong production of first- and second-generation squarks, squark masses below 850 GeV (440 GeV) are excluded for a massless lightest neutralino, assuming mass degenerate (single light-flavour) squarks. In mSUGRA/CMSSM models with tan β = 30, A 0 = −2m 0 and μ > 0, squarks and gluinos of equal mass are excluded for masses below 1700 GeV. Additional limits are set for non-universal Higgs mass models with gaugino mediation and for simplified models involving the pair production of gluinos, each decaying to a top squark and a top quark, with the top squark decaying to a charm quark and a neutralino. These limits extend the region of supersymmetric parameter space excluded by previous searches with the ATLAS detector