Infección vaginal en gestantes

Se realiza un estudio descriptivo de corte transversal con el propósito de describir la situación de la infección vaginal en gestantes de los municipios San Antonio del Sur y El Salvador en 93 gestantes con diagnóstico clínico de infección vaginal de los Grupos Básicos de Trabajo: Hospital Comunitario Docente “IV Congreso” y “Francisco Castro Ceruto”, en el período enero-diciembre de 2006. Para la obtención de los datos se pide consentimiento y luego se aplica entrevista y test de conocimientos. Los resultados muestran que la infección vaginal predomina en gestantes de edades entre 20-29 años de secundaria básica y de estado civil unión consensual. El posible factor que más favoreció la infección es el inadecuado tratamiento del agua para el aseo. Predomina candidiasis, la no correspondencia entre el diagnóstico clínico y microbiológico, tratamiento con nistatina, incumplimiento del tratamiento y nivel inadecuado del conocimiento en las gestantes con infección vaginal en los municipios estudiados

Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

Purpose In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated with significant mortality. Granular data are required for optimizing management, and developing guidelines and clinical trials. Methods We carried out a prospective international cohort study of adult patients (≥ 18 years of age) with HA-BSI treated in intensive care units (ICUs) between June 2019 and February 2021. Results 2600 patients from 333 ICUs in 52 countries were included. 78% HA-BSI were ICU-acquired. Median Sequential Organ Failure Assessment (SOFA) score was 8 [IQR 5; 11] at HA-BSI diagnosis. Most frequent sources of infection included pneumonia (26.7%) and intravascular catheters (26.4%). Most frequent pathogens were Gram-negative bacteria (59.0%), predominantly Klebsiella spp. (27.9%), Acinetobacter spp. (20.3%), Escherichia coli (15.8%), and Pseudomonas spp. (14.3%). Carbapenem resistance was present in 37.8%, 84.6%, 7.4%, and 33.2%, respectively. Difficult-to-treat resistance (DTR) was present in 23.5% and pan-drug resistance in 1.5%. Antimicrobial therapy was deemed adequate within 24 h for 51.5%. Antimicrobial resistance was associated with longer delays to adequate antimicrobial therapy. Source control was needed in 52.5% but not achieved in 18.2%. Mortality was 37.1%, and only 16.1% had been discharged alive from hospital by day-28. Conclusions HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes

Search for new phenomena in events containing a same-flavour opposite-sign dilepton pair, jets, and large missing transverse momentum in root s=13 TeV pp collisions with the ATLAS detector

Funded by SCOAP

Measurement of the exclusive γγ→μ+μ−\gamma \gamma \rightarrow \mu^+ \mu^- process in proton-proton collisions at s=13\sqrt{s}=13 TeV with the ATLAS detector

International audienceThe production of exclusive γγ→μ+μ− events in proton–proton collisions at a centre-of-mass energy of 13 TeV is measured with the ATLAS detector at the LHC, using data corresponding to an integrated luminosity of 3.2 fb −1 . The measurement is performed for a dimuon invariant mass of 12GeV<mμ+μ−<70GeV . The integrated cross-section is determined within a fiducial acceptance region of the ATLAS detector and differential cross-sections are measured as a function of the dimuon invariant mass. The results are compared to theoretical predictions both with and without corrections for absorptive effects