Acoustic localization of tactile interactions for the development of novel tangible interfaces

In this paper we propose different acoustic array processing methods for the localization of tactile interactions with planar surfaces. The aim is to create a new class of tangible interfaces for musical performance that can be obtained by simply applying sensors on existing surfaces. The solutions considered in this paper are mainly based on the measurement and the analysis of the Time-Delay-Of-Arrival (TDOA) over a set of contact sensors, placed around the area of potential contact, and allows us to rapidly localize tactile interactions with reasonable accuracy

Falso Autónomo, Modificación Sustancial de las Condiciones de Trabajo y Garantía Indemnidad

Dictamen con objeto de determinar la realidad laboral que afecta a un conductor que presta sus servicios como TRADE para una empresa tenedora de licencias VTC. Se analiza la cuestión de modificación sustancial de las condiciones de trabajo y una vulneración de la Garantía de Indemnidad como represalia por anunciar denuncia a Inspección de Trabajo.<br /

Análisis del turismo accesible para gente discapacitada en la ciudad de Zaragoza.

La finalidad y objetivo de la realización de este proyecto, se basa en llevar a cabo un análisis de los factores que ayudan a desarrollar el turismo accesible, y de esta forma averiguar si la ciudad de Zaragoza está suficientemente preparada para acoger la afluencia de turistas con capacidad reducida, es decir, acoger y ser capaz de soportar el turismo accesible

Late holocene environmental changes from fluvio-aeolian morpho-sedimentary sequences (Santa María Valley, northwest Argentina)

El valle de Santa María se sitúa en el sector septentrional de las Sierras Pampeanas del Noroeste Argentino.A pesar de sus características áridas, en el pasado albergó importantes poblaciones prehispánicas que pudieronsustentarse mediante la explotación agropastoril de este ambiente, aprovechando fluctuaciones demayor humedad. El estudio de los registros morfosedimentarios fluvio-eólicos de los sectores de El Paso yCafayate han proporcionado datos de interés para una aproximación a la reconstrucción paleoambientalregional durante el Holoceno superior. Para ello se han utilizado técnicas geomorfológicas, estratigráficas,arqueológicas y cronológicas (radiocarbono y fuentes documentales complementadas con edades OSL previas).La intercalación de cenizas volcánicas también ha permitido correlaciones cronológicas al ser utilizadascomo niveles guías. A partir de estos datos se dedujeron alternancias de períodos húmedos y secos a lo largode los últimos 2800 años. Durante las fases más húmedas la estabilidad geomórfica fue suficiente para permitirel desarrollo de suelos y una mejor cobertura vegetal, favoreciendo la ocupación humana. Para la interpretaciónpaleoambiental se han utilizado cronozonas bien definidas en Europa, al no haber denominacionespropias del continente sudamericano. Dentro de la secuencia evolutiva paleoambiental destacan los períodoshúmedos establecidos regionalmente hacia 2800-2500 BP, periodo intermedio Romano (80-280 AD) y la LALIA(Late Antique Little Ice Age) (536-660 AD), mientras que las fases secas abarcan la Época Romana y laAnomalía Cálida Medieval. Por otra parte, para el último milenio se reconocen fases de reactivación de dunasen torno a los años 1000, 1350, 1650 y 1770 AD separados por fluctuaciones más húmedas, algunas evidenciadaspor la presencia de un paleosuelo (siglo XV) y por datos documentales históricos (siglos XVII-XVIII).The Santa María valley is located in the northern sector of the Sierras Pampeanas in Northwest Argentina. In spite of its arid characteristics, it was a densely populated area during the Pre-hispanic period. The populations developed an agropastoral economy, taking advantage of the wetter epochs that characterized some periods. The study of fluvio-aeolian records of the El Paso and Cafayate areas yielded interesting data for regional paleoenvironmental reconstruction. Geomorphological maps, field surveys, and archaeological digs were complemented with the detailed stratigraphic record of several points, together with radiocarbon and OSL dating. Alternating wetter and drier periods were inferred for the last 2,800 years. The wetter phases generated enough stability to allow soil formation and a better plant cover, thus favouring human settlements. For the paleoenvironmental interpretation, well defined European chronozones were used because there are no South American denominations. Within the sequence, some wetter periods stand out, such as the one between 2,800-2,500 BP, the intermediate Roman Period (80-280 AD), and the LALIA (Late Antique Little Ice Age) (536-660 AD), while the drier phases comprise the Roman Epoch and the Medieval Climate Anomaly. Moreover, dune active phases during the last millennium were determined for 1,000, 1,350, 1,650, and 1,770 AD approximately, separated by wetter periods recorded by the presence of a paleosoil (15th century) and historical data (17th and 18th centuries).Facultad de Ciencias Naturales y Muse

Late holocene environmental changes from fluvio-aeolian morpho-sedimentary sequences (Santa María Valley, northwest Argentina)

El valle de Santa María se sitúa en el sector septentrional de las Sierras Pampeanas del Noroeste Argentino.A pesar de sus características áridas, en el pasado albergó importantes poblaciones prehispánicas que pudieronsustentarse mediante la explotación agropastoril de este ambiente, aprovechando fluctuaciones demayor humedad. El estudio de los registros morfosedimentarios fluvio-eólicos de los sectores de El Paso yCafayate han proporcionado datos de interés para una aproximación a la reconstrucción paleoambientalregional durante el Holoceno superior. Para ello se han utilizado técnicas geomorfológicas, estratigráficas,arqueológicas y cronológicas (radiocarbono y fuentes documentales complementadas con edades OSL previas).La intercalación de cenizas volcánicas también ha permitido correlaciones cronológicas al ser utilizadascomo niveles guías. A partir de estos datos se dedujeron alternancias de períodos húmedos y secos a lo largode los últimos 2800 años. Durante las fases más húmedas la estabilidad geomórfica fue suficiente para permitirel desarrollo de suelos y una mejor cobertura vegetal, favoreciendo la ocupación humana. Para la interpretaciónpaleoambiental se han utilizado cronozonas bien definidas en Europa, al no haber denominacionespropias del continente sudamericano. Dentro de la secuencia evolutiva paleoambiental destacan los períodoshúmedos establecidos regionalmente hacia 2800-2500 BP, periodo intermedio Romano (80-280 AD) y la LALIA(Late Antique Little Ice Age) (536-660 AD), mientras que las fases secas abarcan la Época Romana y laAnomalía Cálida Medieval. Por otra parte, para el último milenio se reconocen fases de reactivación de dunasen torno a los años 1000, 1350, 1650 y 1770 AD separados por fluctuaciones más húmedas, algunas evidenciadaspor la presencia de un paleosuelo (siglo XV) y por datos documentales históricos (siglos XVII-XVIII).The Santa María valley is located in the northern sector of the Sierras Pampeanas in Northwest Argentina. In spite of its arid characteristics, it was a densely populated area during the Pre-hispanic period. The populations developed an agropastoral economy, taking advantage of the wetter epochs that characterized some periods. The study of fluvio-aeolian records of the El Paso and Cafayate areas yielded interesting data for regional paleoenvironmental reconstruction. Geomorphological maps, field surveys, and archaeological digs were complemented with the detailed stratigraphic record of several points, together with radiocarbon and OSL dating. Alternating wetter and drier periods were inferred for the last 2,800 years. The wetter phases generated enough stability to allow soil formation and a better plant cover, thus favouring human settlements. For the paleoenvironmental interpretation, well defined European chronozones were used because there are no South American denominations. Within the sequence, some wetter periods stand out, such as the one between 2,800-2,500 BP, the intermediate Roman Period (80-280 AD), and the LALIA (Late Antique Little Ice Age) (536-660 AD), while the drier phases comprise the Roman Epoch and the Medieval Climate Anomaly. Moreover, dune active phases during the last millennium were determined for 1,000, 1,350, 1,650, and 1,770 AD approximately, separated by wetter periods recorded by the presence of a paleosoil (15th century) and historical data (17th and 18th centuries).Facultad de Ciencias Naturales y Muse

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

OBJECTIVE: Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired β-cell function, raised glucose levels, insulin resistance, and type 2 diabetes (T2D). Studies of the insulin processing pathway could provide new insights about T2D pathophysiology. RESEARCH DESIGN AND METHODS: We have conducted a meta-analysis of genome-wide association tests of ∼2.5 million genotyped or imputed single nucleotide polymorphisms (SNPs) and fasting proinsulin levels in 10,701 nondiabetic adults of European ancestry, with follow-up of 23 loci in up to 16,378 individuals, using additive genetic models adjusted for age, sex, fasting insulin, and study-specific covariates. RESULTS: Nine SNPs at eight loci were associated with proinsulin levels (P < 5 × 10(-8)). Two loci (LARP6 and SGSM2) have not been previously related to metabolic traits, one (MADD) has been associated with fasting glucose, one (PCSK1) has been implicated in obesity, and four (TCF7L2, SLC30A8, VPS13C/C2CD4A/B, and ARAP1, formerly CENTD2) increase T2D risk. The proinsulin-raising allele of ARAP1 was associated with a lower fasting glucose (P = 1.7 × 10(-4)), improved β-cell function (P = 1.1 × 10(-5)), and lower risk of T2D (odds ratio 0.88; P = 7.8 × 10(-6)). Notably, PCSK1 encodes the protein prohormone convertase 1/3, the first enzyme in the insulin processing pathway. A genotype score composed of the nine proinsulin-raising alleles was not associated with coronary disease in two large case-control datasets. CONCLUSIONS: We have identified nine genetic variants associated with fasting proinsulin. Our findings illuminate the biology underlying glucose homeostasis and T2D development in humans and argue against a direct role of proinsulin in coronary artery disease pathogenesis

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

Analisis de turismo accesible para gente discapacitada en Zaragoza.

El proyecto está dirigido a un estudio sobre Zaragoza.La finalidad y objetivo del proyecto se basa en llevar a cabo un análisis de los factores los cuales ayudan a desarrollar el turismo, y de esta forma averiguar si la ciudad de Zaragoza está suficientemente preparada para acoger la afluencia de turistas con capacidad reducida, es decir, acoger y ser capaz de soportar el turismo accesible

Análisis del turismo accesible en la ciudad de Zaragoza.

El proyecto está dirigido a un estudio sobre Zaragoza. La finalidad y objetivo del proyecto se basa en llevar a cabo un análisis de los factores los cuales ayudan a desarrollar el turismo, y de esta forma averiguar si la ciudad de Zaragoza está suficientemente preparada para acoger la afluencia de turistas con capacidad reducida, es decir, acoger y ser capaz de soportar el turismo accesible y ver de que forma los demás servicios turísticos se han ido adaptando conforme a las normativas vigentes

Benchmarking Requirements Report : INTELCITIES Deliverable D8.2

This is the second deliverable for WP8, which is developing the prototype of a European cities benchmarking platform, aiming at providing valuable information to support the decision-making process, thus improving City services. The starting point of the report is the realisation of the nature of benchmarking platforms, which try to determine the relevant intellectual capital that explains the competitive gap in each specific activity and to use it as a comparison basis in order to determine the differences with the best competitor in the same activity. This tool will measure and compare the presence, deployment and usage of Information Technologies in cities by using some suitable indicators for the promotion of sustainable cities