O procurador do trabalho e o SUS – Ministério Público do Trabalho e política nacional de saúde do trabalhador: interface entre o papel de promotor social e a busca pela intersetorialidade.

Introduction: The Public Labor Ministry (MPT), a specialized branch of the Public Ministry of the Union (MPU), is one of the fundamental actors in the promotion and protection of workers, and despite it is not expressly mentioned in the National Health and Worker Safety Policy, it has valuable potential for dialogue and promotion of intersectoriality for the construction and implementation of public policies, that provide action in favor of Decent Work, as recommended by the ILO. Objective: To emphasize the role of the MPT as a social promoter of public policies related to health and safety in the work area, specifically with regard to national policies, based on intersectoral practices. Methodology: It is a study of bibliographical and documentary research between 2010 and 2014. The bibliographic search was achieved based on the intersectoriality theme in Health and Safety at Work (HSW) policies in national journals available at the Scielo database and the documentary research was carried out in ministerial documents and official publications of the MPT, both in the same time cut. Results: From the parameters defined in the methodology, 37 articles were identified and analyzed, of which 16 were studies of SCIELO databases. Another 17 were published in official publications of the MPT, of which 7 were studies and 10 were procedural documents, mainly initial petitions for Public Civil Actions (ACPs). Among the 16 studies with intersectoral practices, there was reference to the articulation with MPT in 7 articles, which represents 43.75% of the cases of intersectoral practices in Worker's Health referenced in the databases used in the research. Conclusions: We conclude that the possibilities and potential of intersectoral articulation are broad. Even in the cases of intersectorial actions in which the participation of the MPT was not identified, we showed the potentials of action in each case, whose future prospects imply possibilities of interaction with the social actors of the SUS and others involved with the theme. The studies and speeches show that, even within the SUS, the construction of intersectoral actions is still a challenge, and articulation with the MPT is therefore a major challenge in the effective implementation of the National Policy Occupational Health and Safety. However, the combination of efforts, articulated among all social actors, may be able to modify the scenario that places Brazil in the first rankings of sickness and accidents at the expense of work, against the global picture.Dissertação (Mestrado)Introdução: O Ministério Público do Trabalho (MPT), ramo especializado do Ministério Público da União (MPU), é um dos atores fundamentais nas ações de promoção e proteção do trabalhador e, a despeito de não ter sido expressamente citado na Política Nacional de Saúde e Segurança do Trabalhador, possui valioso potencial de interlocução e de promoção da intersetorialidade para construção e implementação de políticas públicas que proporcionem atuação em prol do trabalho decente, conforme preconizado pela Organização Internacional do Trabalho (OIT). Objetivo: Visibilizar o papel do MPT enquanto promotor social de políticas públicas relacionadas à saúde e à segurança no âmbito do trabalho, especificamente no que diz respeito às políticas nacionais, por meio de práticas intersetoriais. Metodologia: Tratou-se de um estudo de caráter bibliográfico e de pesquisa documental compreendida entre 2010 a 2014. A busca bibliográfica foi feita com base na temática da intersetorialidade nas políticas de saúde e segurança do trabalho (SST) em periódicos nacionais disponibilizados pela biblioteca eletrônica Scielo, e a pesquisa documental foi realizada em documentos ministeriais e publicações oficiais do MPT sobre SST, ambas no mesmo recorte temporal. Resultados: Com base nos parâmetros definidos na metodologia, foram identificados e analisados 33 artigos, sendo 16 estudos coletados na base de dados da Scielo e outros 17 em publicações oficiais do MPT, dentre estes 7 estudos e 10 peças processuais, cuja maioria consiste em petições iniciais de Ações Civis Públicas (ACPs). Dentre os 16 estudos com práticas intersetoriais, houve referência a uma articulação com o MPT em 7 artigos, o que representa 43,75% dos casos de práticas intersetoriais em Saúde do Trabalhador referenciados nas bases de dados utilizadas na pesquisa. Conclusões: Concluímos que as possibilidades e potencialidades de articulação intersetoriais são amplas. Mesmo nos casos de ações intersetoriais em que não foi identificada a participação do MPT, evidenciamos os potenciais de atuação em cada caso, cuja prospecção futura enseja possibilidades de interação com os atores sociais do Sistema Único de Saúde (SUS) e demais envolvidos com a temática. Os estudos e as falas revelam que, na prática, mesmo dentro do SUS, a construção de ações intersetoriais ainda é trabalhosa, e a articulação com o MPT torna-se, portanto, um desafio maior no tocante à implementação efetiva da Política Nacional de Saúde e Segurança do Trabalhador. Porém, a junção de esforços articulados entre todos os atores sociais pode modificar o cenário que coloca o Brasil nas primeiras posições em rankings de adoecimento e acidentes no trabalho no quadro mundial

Atuação intersetorial em saúde do trabalhador: desafios e possibilidades

This article discusses the difficulties and the potentials of intersectoral action in Workers’ Health, starting by the analysis of a concrete case, a work accident which involved 14 workers, in which the National Health System (SUS), the Reference Center in Health (Cerest), the Public Labor Ministry (MPT), a public institution of Higher Education and the workers involved had important participation. The course of investigation of the accident, the various types of education provided to the affected workers and the legal measures, health and surveillance actions, are presented as contributions to the reflections on how an intersectoral action contributes to the integral and resolute attention to the workers’ health. The results point to a local integration as fundamental support for the implementation of intersectoral actions and indicate the importance of the interested workers participation in this process. It also stands out the need for actions in Work Health, such as policies provided by the State, to be effectively incorporated into SUS actions, as a stage of the National Policy on Safety, Health and Environment at Workplace.Neste artigo são discutidas dimensões relacionadas a potencialidades e dificuldades da ação intersetorial em saúde do trabalhador, usando como ponto de partida a análise de um caso concreto, um acidente de trabalho envolvendo 14 trabalhadores, no qual tiveram importante papel: uma unidade de saúde do Sistema Único de Saúde (SUS), o Centro de Referência em Saúde do Trabalhador, o Ministério Público do Trabalho, uma Instituição de Ensino Superior pública e os trabalhadores envolvidos. O percurso de investigação do acidente, as diversas modalidades de assistência oferecidas aos trabalhadores afetados e as medidas jurídicas, de vigilância e de educação em saúde implementadas são apresentados como subsídio às reflexões sobre a atuação intersetorial, necessária para a atenção integral e resolutiva à saúde dos trabalhadores. Os resultados mostram que a articulação local é um ponto de apoio fundamental para a efetivação das ações intersetoriais e que a participação dos trabalhadores, maiores interessados na questão, também produz efeitos importantes nesse processo. Destaca-se ainda a necessidade de que os princípios vinculados à saúde do trabalhador como política de Estado sejam efetivamente incorporados às ações do SUS, enquanto palco sistêmico da Política Nacional de Saúde do Trabalhador

ABORDAGEM DO DIAGNÓSTICO DIFERENCIAL DE DOR TORÁCICA NA EMERGÊNCIA

Chest pain is one of the main causes of emergency hospitalizations, with 4 million visits being made annually. The causes of this condition range from muscle contractures to myocardial infarction and non-cardiogenic causes, such as disorders of the digestive tract. The subjectivity of chest pain becomes the main difficulty in the accurate diagnosis and necessary management for the patient. OBJECTIVE: Find ways to optimize the diagnosis of chest pain in emergency care, aiming to cause less cardiogenic damage to patients. METHODOLOGY: The present study consists of a literary review with a bibliographic survey in databases such as PubMed and Scielo. As an inclusion criterion, articles published in the last 16 years (2007 to 2023) that addressed the researched topic and that were available in digital format were considered. RESULTS: In the first consultation, the reception with the patient's risk classification enabled better flexibility, specification of the severity and risk factors that could be aggravating the patient's life. The most important initial exam is the ECG, which must be performed within 10 minutes, together with biomarkers and the history taken, which are important for the patient's differential diagnosis. FINAL CONSIDERATIONS: it was noticed that time is very important in the differential diagnosis of chest pain. However, speed is hampered by the subjectivity of patients' pain. Therefore, an adequate approach by healthcare professionals in this situation is necessary, in addition to new studies that can optimize emergency protocols.A dor torácica é uma das principais causas de internações de emergência, sendo realizados anualmente 4 milhões de atendimentos. As causas desse quadro têm origem desde contraturas musculares a infarto do miocárdio e causas não cardiogênicas, como acometimentos do trato digestivo. A subjetividade da dor torácica se torna a principal dificuldade para o diagnóstico preciso e a conduta necessária para o paciente.   OBJETIVO: Encontrar formas que otimizem o diagnóstico da dor torácica nos atendimentos de emergência, visando causar menores danos cardiogênicos aos pacientes. METODOLOGIA: O presente estudo consiste em uma revisão literária com  levantamento bibliográfico em bases de dados como o PubMed e Scielo. Como critério de inclusão, foram considerados artigos publicados nos últimos 16 anos (2007 a 2023), que abordassem o tema pesquisado e que estivessem disponíveis em formato digital. RESULTADOS: No primeiro atendimento, a realização do acolhimento com classificação de risco do paciente, possibilitou uma melhor flexibilidade, especificação da gravidade e dos fatores de risco que possam ser agravantes para a vida do paciente. O exame inicial mais importante é o ECG, devendo ser realizado em até 10 minutos, junto aos biomarcadores e a história colhida, sendo importantes para o diagnóstico diferencial do paciente. CONSIDERAÇÕES FINAIS: percebeu-se que o tempo é muito importante no diagnóstico diferencial da dor torácica. Porém, a rapidez é dificultada pela subjetividade das dores dos pacientes. Assim, é necessário uma adequada abordagem do profissional da saúde nessa situação, além de novos estudos que possam otimizar os protocolos na emergência

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study

: The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS® v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 ± 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 ± 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 ± 4.9 and 7.8 ± 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 ± 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity > 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI

AI is a viable alternative to high throughput screening: a 318-target study

: High throughput screening (HTS) is routinely used to identify bioactive small molecules. This requires physical compounds, which limits coverage of accessible chemical space. Computational approaches combined with vast on-demand chemical libraries can access far greater chemical space, provided that the predictive accuracy is sufficient to identify useful molecules. Through the largest and most diverse virtual HTS campaign reported to date, comprising 318 individual projects, we demonstrate that our AtomNet® convolutional neural network successfully finds novel hits across every major therapeutic area and protein class. We address historical limitations of computational screening by demonstrating success for target proteins without known binders, high-quality X-ray crystal structures, or manual cherry-picking of compounds. We show that the molecules selected by the AtomNet® model are novel drug-like scaffolds rather than minor modifications to known bioactive compounds. Our empirical results suggest that computational methods can substantially replace HTS as the first step of small-molecule drug discovery

Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

Peer reviewe

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Search for anomalous couplings in boosted WW/WZ -> l nu q(q)over-bar production in proton-proton collisions at root s=8TeV

Peer reviewe

Electroweak production of two jets in association with a Z boson in proton-proton collisions root s =13 TeV

A measurement of the electroweak (EW) production of two jets in association with a Z boson in proton-proton collisions at root s = 13 TeV is presented, based on data recorded in 2016 by the CMS experiment at the LHC corresponding to an integrated luminosity of 35.9 fb(-1). The measurement is performed in the lljj final state with l including electrons and muons, and the jets j corresponding to the quarks produced in the hard interaction. The measured cross section in a kinematic region defined by invariant masses m(ll) > 50 GeV, m(jj) > 120 GeV, and transverse momenta P-Tj > 25 GeV is sigma(EW) (lljj) = 534 +/- 20 (stat) fb (syst) fb, in agreement with leading-order standard model predictions. The final state is also used to perform a search for anomalous trilinear gauge couplings. No evidence is found and limits on anomalous trilinear gauge couplings associated with dimension-six operators are given in the framework of an effective field theory. The corresponding 95% confidence level intervals are -2.6 <cwww/Lambda(2) <2.6 TeV-2 and -8.4 <cw/Lambda(2) <10.1 TeV-2. The additional jet activity of events in a signal-enriched region is also studied, and the measurements are in agreement with predictions.Peer reviewe