The configuration, sensitivity and rapid retreat of the Late Weichselian Icelandic ice sheet

The fragmentary glacial-geological record across the Icelandic continental shelf has hampered reconstruction of the volume, extent and chronology of the Late Weichselian ice sheet particularly in key offshore zones. Marine geophysical data collected over the last two decades reveal that the ice sheet likely attained a continental shelf-break position in all sectors during the Last Glacial Maximum, though its precise timing and configuration remains largely unknown. Within this context, we review the available empirical evidence and use a well-constrained three-dimensional thermomechanical model to investigate the drivers of an extensive Late Weichselian Icelandic ice-sheet, its sensitivity to environmental forcing, and phases of deglaciation. Our reconstruction attains the continental shelf break across all sectors with a total ice volume of 5.96×105km3 with high precipitation rates being critical to forcing extensive ice sheet flow offshore. Due to its location astride an active mantle plume, a relatively fast and dynamic ice sheet with a low aspect ratio is maintained. Our results reveal that once initial ice-sheet retreat was triggered through climate warming at 21.8 ka BP, marine deglaciation was rapid and accomplished in all sectors within c. 5 ka at a mean rate of 71 Gt of mass loss per year. This rate of ice wastage is comparable to contemporary rates observed for the West Antarctic ice sheet. The ice sheet subsequently stabilised on shallow pinning points across the near shelf for two millennia, but abrupt atmospheric warming during the Bølling Interstadial forced a second, dramatic collapse of the ice sheet onshore with a net wastage of 221 Gt a−1 over 750 years, analogous to contemporary Greenland rates of mass loss. Geothermal conditions impart a significant control on the ice sheet's transient response, particularly during phases of rapid retreat. Insights from this study suggests that large sectors of contemporary ice sheets overlying geothermally active regions, such as Siple Coast, Antarctica, and NE Greenland, have the potential to experience rapid phases of mass loss and deglaciation once initial retreat is initiated

Complex circular subsidence structures in tephra deposited on large blocks of ice: Varða tuff cone, Öræfajökull, Iceland

Several broadly circular structures up to 16 m in diameter, into which higher strata have sagged and locally collapsed, are present in a tephra outcrop on southwest Öræfajökull, southern Iceland. The tephra was sourced in a nearby basaltic tuff cone at Varða. The structures have not previously been described in tuff cones, and they probably formed by the melting out of large buried blocks of ice emplaced during a preceding jökulhlaup that may have been triggered by a subglacial eruption within the Öræfajökull ice cap. They are named ice-melt subsidence structures, and they are analogous to kettle holes that are commonly found in proglacial sandurs and some lahars sourced in ice-clad volcanoes. The internal structure is better exposed in the Varða examples because of an absence of fluvial infilling and reworking, and erosion of the outcrop to reveal the deeper geometry. The ice-melt subsidence structures at Varða are a proxy for buried ice. They are the only known evidence for a subglacial eruption and associated jökulhlaup that created the ice blocks. The recognition of such structures elsewhere will be useful in reconstructing more complete regional volcanic histories as well as for identifying ice-proximal settings during palaeoenvironmental investigations

Lateglacial to Holocene relative sea-level changes in the Stykkishólmur area, northern Snæfellsnes, Iceland

Comparatively little research has been undertaken on relative sea-level (RSL) change in western Iceland. This paper presents the results of diatom, tephrochronological and radiocarbon analyses on six isolation basins and two coastal lowland sediment cores from the Stykkishólmur area, northern Snæfellsnes, western Iceland. The analyses provide a reconstruction of Lateglacial to mid-Holocene RSL changes in the region. The marine limit is measured to 65–69 m above sea level (asl), with formation being estimated at 13.5 cal ka BP. RSL fall initially occurred rapidly following marine limit formation, until ca. 12.6 cal ka BP, when the rate of RSL fall decreased. RSL fell below present in the Stykkishólmur area during the early Holocene (by ca. 10 cal ka BP). The rates of RSL change noted in the Stykkishólmur area demonstrate lesser ice thicknesses in Snæfellsnes than Vestfirðir during the Younger Dryas, when viewed in the regional context. Consequently, the data provide an insight into patterns of glacio-isostatic adjustment surrounding Breiðafjörður, a hypothesized major ice stream at the Last Glacial Maximum

Active retreat of a Late Weichselian marine-terminating glacier: an example from Melasveit, western Iceland

Large and complete glaciotectonic sequences formed by marine-terminating glaciers are rarely observed on land, hampering our understanding of the behaviour of such glaciers and the processes operating at their margins. During the Late Weichselian in western Iceland, an actively retreating marine-terminating glacier resulted in the large-scale deformation of a sequence of glaciomarine sediments. Due to isostatic rebound since the deglaciation, these formations are now exposed in the coastal cliffs of Belgsholt and Melabakkar-Ásbakkar in the Melasveit district, and provide a detailed record of past glacier dynamics and the inter-relationships between glaciotectonic and sedimentary processes at the margin of this marine-terminating glacier. A comprehensive study of the sedimentology and glaciotectonic architecture of the coastal cliffs reveals a series of subaquatic moraines formed by a glacier advancing from Borgarfjörður to the north of the study area. Analyses of the style of deformation within each of the moraines demonstrate that they were primarily built up by ice-marginal/proglacial thrusting and folding of marine sediments, as well as deposition and subsequent deformation of ice-marginal subaquatic fans. The largest of the moraines exposed in the Melabakkar-Ásbakkar section is over 1.5 km wide and 30 m high and indicates the maximum extent of the Borgarfjörður glacier. Generally, the other moraines in the series become progressively younger towards the north, each designating an advance or stillstand position as the glacier oscillated during its overall northward retreat. During this active retreat, glaciomarine sediments rapidly accumulated in front of the glacier providing material for new moraines. As the glacier finally receded from the area, the depressions between the moraines were infilled by continued glaciomarine sedimentation. This study highlights the dynamics of marine-terminating glaciers and may have implications for the interpretation of their sedimentological and geomorphological records

The triggering factors of the Móafellshyrna debris slide in northern Iceland: Intense precipitation, earthquake activity and thawing of mountain permafrost

On the 20th September 2012, a large debris slide occurred in the Móafellshyrna Mountain in the Tröllaskagi peninsula, central north Iceland. Our work describes and discusses the relative importance of the three factors that may have contributed to the failure of the slope: intense precipitation, earthquake activity and thawing of ground ice. We use data from weather stations, seismometers, witness reports and field observations to examine these factors. The slide initiated after an unusually warm and dry summer followed by a month of heavy precipitation. Furthermore, the slide occurred after three seismic episodes, whose epicentres were located ~60km NNE of Móafellshyrna Mountain. The main source of material for the slide was ice-rich colluvium perched on a topographic bench. Blocks of ice-cemented colluvium slid and then broke off the frontal part of the talus slope, and the landslide also involved a component of debris slide, which mobilized around 312,000-480,000m(3) (as estimated from field data and aerial images of erosional morphologies). From our analysis we infer that intense precipitation and seismic activity prior to the slide are the main preparatory factors for the slide. The presence of ice-cemented blocks in the slide's deposits leads us to infer that deep thawing of ground ice was likely the final triggering factor. Ice-cemented blocks of debris have been observed in the deposits of two other recent landslides in northern Iceland, in the Torfufell Mountain and the Árnesfjall Mountain. This suggests that discontinuous mountain permafrost is degrading in Iceland, consistent with the decadal trend of increasing atmospheric temperature in Iceland. This study highlights a newly identified hazard in Iceland: landslides as a result of ground ice thaw. Knowledge of the detailed distribution of mountain permafrost in colluvium on the island is poorly constrained and should be a priority for future research in order to identify zones at risk from this hazard

Outdoor Education in Italian Kindergartens: How Teachers Perceive Child Developmental Trajectories

Outdoor Education (OE) refers to organized experiential education that takes place in the outdoor, characterized by action-centered and thematic learning processes. Literature shows how OE may have beneficial effects on different areas of child development, including cognitive abilities, social skills, and motor development. This relationship is not necessarily linear, but moderated by different variables. Until now, few studies have examined, using rigorous methods, the role of OE in children's development and studies of preschool aged children remain lacking. The current study aimed to explore teachers' perceptions of children's developmental trajectories over 2 school years, investigating whether teachers' perceptions differed between two kindergartens, one characterized by a consolidated OE approach and the other one characterized by a more traditional method of education. The sample was composed of 20 teachers, evaluating 93 children aged 3–5 (M = 46.95 months, SD = 6.73; 42 males): 13 teachers were from a traditional kindergarten (Traditional Group- TG) and evaluated 52 children; 7 teachers were from an OE kindergarten (Outdoor Group—OE) and observed 41 children. All the teachers completed the Kuno Beller Developmental Tables (Mantovani, 1995), in order to describe specific child developmental areas in 4 consecutive moments during 2 school years (T1-T2: January-May 2014; T3-T4: October 2014-May 2015). The 20 teachers also completed the “Outdoor Activities/Trips Diary,” an instrument created for this study to collect qualitative data on the characteristics of outdoor activities. Results showed that, in all the developmental areas, OE teachers perceived higher scores over time were found for the Outdoor Group compared to the Traditional one. Specifically, GLM ANOVAs Repeated Measures revealed a significant interaction of the 2 variables Time and Groups (p < 0.001): contrast analyses showed that OE children, compared to the TG children, were perceived by their teachers with higher levels in all developmental areas at T1 and T2, but not at T3 and T4. The findings suggest that the OE activites, compared to indoor ones and according to teachers' perceptions, offer greater opportunities to promote the child's development at different levels, especially when children are younger. Future studies are recommended analyzing possible moderating variables and long term effects of OE

MAP1B mutations cause intellectual disability and extensive white matter deficit

Publisher's version (útgefin grein). Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Discovery of coding variants in genes that confer risk of neurodevelopmental disorders is an important step towards understanding the pathophysiology of these disorders. Wholegenome sequencing of 31,463 Icelanders uncovers a frameshift variant (E712KfsTer10) in microtubule-associated protein 1B (MAP1B) that associates with ID/low IQ in a large pedigree (genome-wide corrected P = 0.022). Additional stop-gain variants in MAP1B (E1032Ter and R1664Ter) validate the association with ID and IQ. Carriers have 24% less white matter (WM) volume (β = −2.1SD, P = 5.1 × 10−8), 47% less corpus callosum (CC) volume (β = −2.4SD, P = 5.5 × 10−10) and lower brain-wide fractional anisotropy (P = 6.7 × 10−4). In summary, we show that loss of MAP1B function affects general cognitive ability through a profound, brain-wide WM deficit with likely disordered or compromised axons.We are grateful to the participants and we thank the psychologists, nurses and staff, in particular Berglind Eiriksdottir, at the Research Recruitment Center and technicians and staff at Röntgen Domus. We also thank the staff at deCODE genetics core facilities and all our colleagues for their important contribution to this work. L.J. received support from the Swedish Society of Medicine, the Swedish Brain Foundation and Swedish Society for Medical Research. The research leading to these results has received support from the Innovative Medicines Initiative Joint Undertaking under grant agreements’ no. 115008 (NEWMEDS) and no. 115300 (EUAIMS) of which resources are composed of EFPIA in-kind contribution and financial contribution from the European Union’s Seventh Framework Programme (EU-FP7/2007-2013), EU-FP7 funded grant no. 602450 (IMAGEMEND) and EU funded FP7-People-2011-IAPP grant agreement no. 286213 (PsychDPC).Peer Reviewe

Lipoprotein(a) Concentration and Risks of Cardiovascular Disease and Diabetes

Publisher's version (útgefin grein)Background: Lipoprotein(a) [Lp(a)] is a causal risk factor for cardiovascular diseases that has no established therapy. The attribute of Lp(a) that affects cardiovascular risk is not established. Low levels of Lp(a) have been associated with type 2 diabetes (T2D). Objectives: This study investigated whether cardiovascular risk is conferred by Lp(a) molar concentration or apolipoprotein(a) [apo(a)] size, and whether the relationship between Lp(a) and T2D risk is causal. Methods: This was a case-control study of 143,087 Icelanders with genetic information, including 17,715 with coronary artery disease (CAD) and 8,734 with T2D. This study used measured and genetically imputed Lp(a) molar concentration, kringle IV type 2 (KIV-2) repeats (which determine apo(a) size), and a splice variant in LPA associated with small apo(a) but low Lp(a) molar concentration to disentangle the relationship between Lp(a) and cardiovascular risk. Loss-of-function homozygotes and other subjects genetically predicted to have low Lp(a) levels were evaluated to assess the relationship between Lp(a) and T2D. Results: Lp(a) molar concentration was associated dose-dependently with CAD risk, peripheral artery disease, aortic valve stenosis, heart failure, and lifespan. Lp(a) molar concentration fully explained the Lp(a) association with CAD, and there was no residual association with apo(a) size. Homozygous carriers of loss-of-function mutations had little or no Lp(a) and increased the risk of T2D. Conclusions: Molar concentration is the attribute of Lp(a) that affects risk of cardiovascular diseases. Low Lp(a) concentration (bottom 10%) increases T2D risk. Pharmacologic reduction of Lp(a) concentration in the 20% of individuals with the greatest concentration down to the population median is predicted to decrease CAD risk without increasing T2D risk.Peer Reviewe

A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease

Publisher's version (útgefin grein) Publisher’s note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Mutations in genes encoding subunits of the phagocyte NADPH oxidase complex are recognized to cause chronic granulomatous disease (CGD), a severe primary immunodeficiency. Here we describe how deficiency of CYBC1, a previously uncharacterized protein in humans (C17orf62), leads to reduced expression of NADPH oxidase’s main subunit (gp91phox) and results in CGD. Analyzing two brothers diagnosed with CGD we identify a homozygous loss-of-function mutation, p.Tyr2Ter, in CYBC1. Imputation of p.Tyr2Ter into 155K chipgenotyped Icelanders reveals six additional homozygotes, all with signs of CGD, manifesting as colitis, rare infections, or a severely impaired PMA-induced neutrophil oxidative burst. Homozygosity for p.Tyr2Ter consequently associates with inflammatory bowel disease (IBD) in Iceland (P = 8.3 × 10−8; OR = 67.6), as well as reduced height (P = 3.3 × 10−4; −8.5 cm). Overall, we find that CYBC1 deficiency results in CGD characterized by colitis and a distinct profile of infections indicative of macrophage dysfunction.We wish to thank the family of the two probands, as well as all the other individuals who participated in the study and whose contribution made this work possible.Peer Reviewe

Constraining bedrock erosion during extreme flood events

The importance of high-magnitude, short-lived flood events in controlling the evolution of bedrock landscapes is not well understood. During such events, erosion processes can shift from one regime to another upon the passing of thresholds, resulting in abrupt landscape changes that can have a long lasting legacy on landscape morphology. Geomorphological mapping and topographic analysis document the evidence for, and impact of, extreme flood events within the Jökulsárgljúfur canyon (North-East Iceland). Surface exposure dating using cosmogenic 3He of fluvially sculpted bedrock surfaces determines the timing of the floods that eroded the canyon and helps constrain the mechanisms of bedrock erosion during these events. Once a threshold flow depth has been exceeded, the dominant erosion mechanism becomes the toppling and transportation of basalt lava columns and erosion occurs through the upstream migration of knickpoints. Surface exposure ages allow identification of three periods of rapid canyon cutting during erosive flood events about 9, 5 and 2 ka ago, when multiple active knickpoints retreated large distances (> 2 km), each leading to catastrophic landscape change within the canyon. A single flood event ~9 ka ago formed, and then abandoned, Ásbyrgi canyon, eroding 0.14 km3 of rock. Flood events ~5 and ~2 ka ago eroded the upper 5 km of the Jökulsárgljúfur canyon through the upstream migration of vertical knickpoints such as Selfoss, Dettifoss and Hafragilsfoss. Despite sustained high discharge of sediment-rich glacial meltwater (ranging from 100 to 500 m3 s-1); there is no evidence for a transition to an abrasion-dominated erosion regime since the last erosive flood: the vertical knickpoints have not diffused over time and there is no evidence of incision into the canyon floor. The erosive signature of the extreme events is maintained in this landscape due to the nature of the bedrock, the discharge of the river, large knickpoints and associated plunge pools. The influence of these controls on the dynamics of knickpoint migration and morphology are explored using an experimental study. The retreat rate of knickpoints is independent of both mean discharge, and temporal variability in the hydrograph. The dominant control on knickpoint retreat is the knickpoint form which is set by the ratio of channel flow depth to knickpoint height. Where the knickpoint height is five times greater than the flow depth, the knickpoints developed undercutting plunge pools, accelerating the removal of material from the knickpoint base and the overall retreat rate. Smaller knickpoints relative to the flow depth were more likely to diffuse from a vertical step into a steepened reach or completely as the knickpoint retreated up the channel. These experiments challenge the established assumption in models of landscape evolution that a simple relationship exists between knickpoint retreat and discharge/drainage area. In order to fully understand how bedrock channels, and thus landscapes, respond and recover to transient forcing, further detailed study of the mechanics of erosion processes at knickpoints is required