5,024 research outputs found

    Monitoring and Analysis of Frozen Debris Lobes, Phase IB

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    INE/AUTC 15.0

    A1c Reduction and Weight Loss in a Veteran Population Using GLP-1-RAs

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    Background: Diabetes mellitus is a metabolic disorder defined by high blood glucose. Glucagon-like peptide-1 receptor agonists (GLP-1-RAs) are a newer class of medications that offer potential 2 to 3 kg weight loss and a 1% to 1.5% decrease in A1c. At the Indianapolis Veterans Affairs Medical Center (VAMC), GLP-1-RAs are non-formulary. Objectives: Primary outcomes included mean change in weight, body mass index (BMI) and A1c in VAMC patients. Secondary outcomes included the comparison to published values, analysis of insulin needs, and analysis of GLP-1-RA discontinuation reasons. Methods: Indianapolis VAMC patients ages 18-80 with type 2 diabetes who started a GLP-1-RA from January 1, 2010 to July 1, 2016 were identified. The following data points were gathered at monthly intervals before spreading out to biannual: specific GLP1-RA and dose; weight; BMI; A1c; other diabetes medications; insulin requirements; and any reason for discontinuation. This report is an analysis of the baseline, 24 week, and 48 week data. Results: With a mean age of 62.2 years and a 90.2% male population, the cohort decreased their weight from baseline by 2.5 kg at 24 weeks of use and 3.6 kg at 48 weeks. A1c decreased by 1.3% in the first 24 weeks and was maintained at 48 weeks. Insulin use decreased during the study. Seven percent of patients discontinued GLP-1- RAs due to GI intolerance. Conclusion: GLP-1-RAs have a similar effect on weight and A1c in the veteran population compared to previous study populations. Based on this and further research, GLP-1-RA use may be expanded in the future

    Evaluation of MEMS-based In-place Inclinometers in Cold Regions

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    INE/AUTC 12.3

    Collapsible nozzle extension for rocket engines Patent

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    Development of collapsible nozzle extension for rocket engine

    Unstable Slope Management Program

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    INE/AUTC 11.1

    Beating the Bluebook Blues: A Response to Judge Posner

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    Judge Richard A. Posner\u27s recent critique (The Bluebook Blues) of the maddening hypertrophy of The Bluebook is surely a refreshing voice of sanity for the multitudes of law students and legal professionals who have had occasion to consult it. Even at Harvard Law School, the home of its founding institutional sponsor, The Bluebook\u27s labyrinthine rules annually aggravate a fresh crop of otherwise remarkably stoic future lawyers. But while many of Posner\u27s observations regarding The Bluebook are astute, we posit that both form and uniformity are important for citations, and we suggest citation-formatting software as a means of maximizing the utility of legal citations while minimizing the burden of creating them

    Monitoring and Analysis of Frozen Debris Lobes, Phase I

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    INE/AUTC 12.2

    Is the First Amendment at Risk?

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    Since the establishment of the Bill of Rights on December 15th 1791, Freedom of Speech has been one of the more controversial topics found within the first ten amendments. The Supreme Court has changed their interpretation of the 1st Amendment, Freedom of Speech clause, due to the cultural shifts of each generation. Recent cases have made technology a major factor for laws needing to be changed in order to protect people’s rights. In conclusion, the definition of freedom of speech will continuously change due to the progress in technology. The last 10 years have demonstrated the need for changes. There have been several court cases that have challenged the definition of freedom of speech when dealing with social media and electronics. While some changes need to happen, the federal government has the responsibility to protect the Freedom of Speech for all Americans even with the changes to come
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