VARIACIÓN TEMPORAL DE LA HERPETOFAUNA EN EL CENTRO ECOLÓGICO WETSO, ANTIGUO PANAJUNGLA, PARQUE INTERNACIONAL LA AMISTAD (PILA), BOCAS DEL TORO

To determine the temporal variation of the herpetofauna in the Wetso Ecological Center, PILA, Bocas del Toro, seven samplings were carried out during the rainy season of 2019 and the dry season of 2021, in the populations of amphibians and reptiles. As a result, 47 species were identified, of which 25 correspond to amphibians grouped in an order, 9 families, 19 genera; another 22 species correspond to reptiles; including two orders, 12 families, and 17 genera. For amphibians, the Shannon Wiener diversity index reached H'= 2.89 and the evenness index (J'= 0.98), for reptiles the Shannon Wiener diversity index reached H'= 2.21 and the evenness index (J'= 0.90). The most abundant or common species for amphibians was O. pumilio with 14.56% and for reptiles G. albogularis with 34.2%. The correlation between richness and average daily precipitation (mm), showed that there is a direct relationship between the richness of the observed herpetofauna and precipitation, with r= 0.70 for amphibians, and r= - 0.75 for reptiles. With this information, a seasonal pattern was presented, being the rainy season favorable for amphibians and the dry season favorable for reptiles.Con el objetivo de determinar la variación temporal de la herpetofauna en el Centro Ecológico Wetso, PILA, Bocas del Toro, se realizaron siete muestreos durante la estación lluviosa del 2019 y la estación seca del 2021, en las poblaciones de anfibios y reptiles. Como resultado, se identificaron 47 especies, de las cuales 25 corresponden a anfibios agrupadas en un orden, 9 familias, 19 géneros; otras 22 especies corresponden a reptiles; incluyendo dos órdenes, 12 familias y 17 géneros. Para anfibios el índice de diversidad de Shannon Wiener alcanzó H’= 2.89 y el índice de equitatividad (J’= 0.98), para los reptiles el índice de diversidad de Shannon Wiener alcanzó H’= 2.21 y el índice de equitatividad (J’= 0.90). Las especie más abundante o común para anfibios fue O. pumilio con 14.56% y para los reptiles G. albogularis con 34.2%. La correlación entre riqueza y precipitación promedio diaria (mm), demostró que hay una relación directa entre la riqueza de la herpetofauna observada y la precipitación, con r= 0.70 para anfibios, y r= - 0.75 para reptiles. Con esta información se presentó un patrón estacional, siendo la estación lluviosa favorable para los anfibios y la estación seca favorable para los reptiles

Ultracool dwarf benchmarks with \emph{Gaia} primaries

This article has been accepted for publication in Monthly Notices of the Royal Astronomical Society. © 2017 The Author(s). Published by Oxford University Press on behalf of the Royal Astronomical Society. All rights reserved.We explore the potential of \emph{Gaia} for the field of benchmark ultracool/brown dwarf companions, and present the results of an initial search for metal-rich/metal-poor systems. A simulated population of resolved ultracool dwarf companions to \emph{Gaia} primary stars is generated and assessed. Of order $\sim$24,000 companions should be identifiable outside of the Galactic plane ($|b| > 10\,$deg) with large-scale ground- and space-based surveys including late M, L, T, and Y types. Our simulated companion parameter space covers $0.02 \le M/M_{\odot} \le 0.1$, $0.1 \le {\rm age/Gyr} \le 14$, and $-2.5 \le {\rm [Fe/H]} \le 0.5$, with systems required to have a false alarm probability $$0.6\, kau}\,Peer reviewedFinal Accepted Versio

GRB 060121: Implications of a Short/Intermediate Duration Gamma-Ray Burst at High Redshift

Since the discovery of the first short-hard gamma-ray burst afterglows in 2005, the handful of observed events have been found to be embedded in nearby (z < 1), bright underlying galaxies. We present multiwavelength observations of the short-duration burst GRB 060121, which is the first observed to clearly outshine its host galaxy (by a factor >10^2). A photometric redshift for this event places the progenitor at a most probable redshift of z = 4.6, with a less probable scenario of z = 1.7. In either case, GRB 060121 could be the farthermost short-duration GRB detected to date and implies an isotropic-equivalent energy release in gamma-rays comparable to that seen in long-duration bursts. We discuss the implications of the released energy on the nature of the progenitor. These results suggest that GRB 060121 may belong to a family of energetic short-duration events, lying at z > 1 and whose optical afterglows would outshine their host galaxies, unlike the first short-duration GRBs observed in 2005. The possibility of GRB 060121 being an intermediate duration burst is also discussed.Comment: 4 pages, 4 figures. Submitted to ApJ

Effectiveness and Safety of the Switch from Remicade® to CT-P13 in Patients with Inflammatory Bowel Disease

[Background and Aims] To evaluate the clinical outcomes in patients with IBD after switching from Remicade® to CT-P13 in comparison with patients who maintain Remicade®.[Methods] Patients under Remicade® who were in clinical remission with standard dosage at study entry were included. The ‘switch cohort’ [SC] comprised patients who made the switch from Remicade® to CT-P13, and the ‘non-switch’ cohort [NC] patients remained under Remicade®.[Results] A total of 476 patients were included: 199 [42%] in the SC and 277 [58%] in the NC. The median follow-up was 18 months in the SC and 23 months in the NC [p < 0.01]. Twenty-four out of 277 patients relapsed in the NC; the incidence of relapse was 5% per patient-year. The cumulative incidence of relapse was 2% at 6 months and 10% at 24 months in this group. Thirty-eight out of 199 patients relapsed in the SC; the incidence rate of relapse was 14% per patient-year. The cumulative incidence of relapse was 5% at 6 months and 28% at 24 months. In the multivariate analysis, the switch to CT-P13 was associated with a higher risk of relapse (HR = 3.5, 95% confidence interval [CI] = 2–6). Thirteen percent of patients had adverse events in the NC, compared with 6% in the SC [p < 0.05].[Conclusions] Switching from Remicade® to CT-P13 might be associated with a higher risk of clinical relapse, although this fact was not supported in our study by an increase in objective markers of inflammation. The nocebo effect might have influenced this result. Switching from Remicade® to CT-P13 was safe.This research has been funded by grants from the Instituto de Salud Carlos III [PI13/00041 and FI17/00143]

Measurement of charm production at central rapidity in proton-proton collisions at s=2.76\sqrt{s} = 2.76 TeV

The $p_{\rm T}$-differential production cross sections of the prompt (B feed-down subtracted) charmed mesons D$^0$, D$^+$, and D$^{*+}$ in the rapidity range $|y|<0.5$, and for transverse momentum $1< p_{\rm T} <12$ GeV/$c$, were measured in proton-proton collisions at $\sqrt{s} = 2.76$ TeV with the ALICE detector at the Large Hadron Collider. The analysis exploited the hadronic decays D$^0 \rightarrow$K$\pi$, D$^+ \rightarrow$K$\pi\pi$, D$^{*+} \rightarrow$D$^0\pi$, and their charge conjugates, and was performed on a $L_{\rm int} = 1.1$ nb$^{-1}$ event sample collected in 2011 with a minimum-bias trigger. The total charm production cross section at $\sqrt{s} = 2.76$ TeV and at 7 TeV was evaluated by extrapolating to the full phase space the $p_{\rm T}$-differential production cross sections at $\sqrt{s} = 2.76$ TeV and our previous measurements at $\sqrt{s} = 7$ TeV. The results were compared to existing measurements and to perturbative-QCD calculations. The fraction of cdbar D mesons produced in a vector state was also determined.Comment: 20 pages, 5 captioned figures, 4 tables, authors from page 15, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/307

A Gap Analysis Methodology for Collecting Crop Genepools: A Case Study with Phaseolus Beans

Background The wild relatives of crops represent a major source of valuable traits for crop improvement. These resources are threatened by habitat destruction, land use changes, and other factors, requiring their urgent collection and long-term availability for research and breeding from ex situ collections. We propose a method to identify gaps in ex situ collections (i.e. gap analysis) of crop wild relatives as a means to guide efficient and effective collecting activities. Methodology/Principal Findings The methodology prioritizes among taxa based on a combination of sampling, geographic, and environmental gaps. We apply the gap analysis methodology to wild taxa of the Phaseolus genepool. Of 85 taxa, 48 (56.5%) are assigned high priority for collecting due to lack of, or under-representation, in genebanks, 17 taxa are given medium priority for collecting, 15 low priority, and 5 species are assessed as adequately represented in ex situ collections. Gap “hotspots”, representing priority target areas for collecting, are concentrated in central Mexico, although the narrow endemic nature of a suite of priority species adds a number of specific additional regions to spatial collecting priorities. Conclusions/Significance Results of the gap analysis method mostly align very well with expert opinion of gaps in ex situ collections, with only a few exceptions. A more detailed prioritization of taxa and geographic areas for collection can be achieved by including in the analysis predictive threat factors, such as climate change or habitat destruction, or by adding additional prioritization filters, such as the degree of relatedness to cultivated species (i.e. ease of use in crop breeding). Furthermore, results for multiple crop genepools may be overlaid, which would allow a global analysis of gaps in ex situ collections of the world's plant genetic resource

Impact of biological agents on postsurgical complications in inflammatory bowel disease: A multicentre study of Geteccu

Background: The impact of biologics on the risk of postoperative complications (PC) in inflammatory bowel disease (IBD) is still an ongoing debate. This lack of evidence is more relevant for ustekinumab and vedolizumab. Aims: To evaluate the impact of biologics on the risk of PC. Methods: A retrospective study was performed in 37 centres. Patients treated with biologics within 12 weeks before surgery were considered “exposed”. The impact of the exposure on the risk of 30-day PC and the risk of infections was assessed by logistic regression and propensity score-matched analysis. Results: A total of 1535 surgeries were performed on 1370 patients. Of them, 711 surgeries were conducted in the exposed cohort (584 anti-TNF, 58 vedolizumab and 69 ustekinumab). In the multivariate analysis, male gender (OR: 1.5; 95% CI: 1.2–2.0), urgent surgery (OR: 1.6; 95% CI: 1.2–2.2), laparotomy approach (OR: 1.5; 95% CI: 1.1–1.9) and severe anaemia (OR: 1.8; 95% CI: 1.3–2.6) had higher risk of PC, while academic hospitals had significantly lower risk. Exposure to biologics (either anti-TNF, vedolizumab or ustekinumab) did not increase the risk of PC (OR: 1.2; 95% CI: 0.97–1.58), although it could be a risk factor for postoperative infections (OR 1.5; 95% CI: 1.03–2.27). Conclusions: Preoperative administration of biologics does not seem to be a risk factor for overall PC, although it may be so for postoperative infections