Gender Matters! Analyzing Global Cultural Gender Preferences for Venues Using Social Sensing

Gender differences is a phenomenon around the world actively researched by social scientists. Traditionally, the data used to support such studies is manually obtained, often through surveys with volunteers. However, due to their inherent high costs because of manual steps, such traditional methods do not quickly scale to large-size studies. We here investigate a particular aspect of gender differences: preferences for venues. To that end we explore the use of check-in data collected from Foursquare to estimate cultural gender preferences for venues in the physical world. For that, we first demonstrate that by analyzing the check-in data in various regions of the world we can find significant differences in preferences for specific venues between gender groups. Some of these significant differences reflect well-known cultural patterns. Moreover, we also gathered evidence that our methodology offers useful information about gender preference for venues in a given region in the real world. This suggests that gender and venue preferences observed may not be independent. Our results suggests that our proposed methodology could be a promising tool to support studies on gender preferences for venues at different spatial granularities around the world, being faster and cheaper than traditional methods, besides quickly capturing changes in the real world

Towards a versatile and multidimensional framework to analyse regional governance

Regional governance has received growing attention, not only from researchers, but also from politicians and practitioners of regional development. The understanding and usage of the concept, however, are highly heterogeneous: sometimes regional governance is described or explained in terms of its characteristics, processes and impacts, while at other times, it is framed as a tool for regional development. This article develops a definition and framework for a systematic assessment of various regional governance forms. For this purpose, it draws on material from a three-round Delphi survey among practitioners and researchers who are experts of regional governance. On this basis, a consolidated definition of regional governance is proposed as ‘the vertical and horizontal coordination of regional transformation processes beyond administrative boundaries by state and non-state actors’. Furthermore, the framework identifies five dimensions of regional governance: (a) participation, (b) bindingness, (c) formalisation, (d) regional autonomy and (e) power relations. These dimensions are disaggregated into a total of 21 indicators to systematically describe and analyse different regional governance forms., Regional governance has received growing attention, not only from researchers, but also from politicians and practitioners of regional development. The understanding and usage of the concept, however, are highly heterogeneous: sometimes regional governance is described or explained in terms of its characteristics, processes and impacts, while at other times, it is framed as a tool for regional development. This article develops a definition and framework for a systematic assessment of various regional governance forms. For this purpose, it draws on material from a three-round Delphi survey among practitioners and researchers who are experts of regional governance. On this basis, a consolidated definition of regional governance is proposed as ‘the vertical and horizontal coordination of regional transformation processes beyond administrative boundaries by state and non-state actors’. Furthermore, the framework identifies five dimensions of regional governance: (a) participation, (b) bindingness, (c) formalisation, (d) regional autonomy and (e) power relations. These dimensions are disaggregated into a total of 21 indicators to systematically describe and analyse different regional governance forms

Myosin Va’s adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro

Significance Inner organization of eukaryotic cells intimately depends on the active transport of diverse intracellular cargo on the ubiquitous actin and microtubule networks. The underlying mechanisms of such directional transport processes have been of outstanding interest. We studied a motor complex composed of Rab27a, melanophilin, and myosin Va and found, surprisingly, that the adaptor protein melanophilin toggled the binding preference toward actin or microtubules in vitro. Our results offer unexpected mechanistic insights into biasing the directionality of a moving organelle on the cytoskeleton through phospho-targeting the adaptor protein rather than its motor in vivo.</jats:p

Inhibitors of GlyT1 Affect Glycine Transport via Discrete Binding Sites

ABSTRACT In the forebrain, synaptic glycine concentrations are regulated through the glycine transporter GlyT1. Because glycine is a coagonist of the N-methyl-D-aspartate (NMDA) receptor (NMDAR), which has been implicated in schizophrenia, inhibition of GlyT1 is thought to provide an option for the treatment of schizophrenia

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

Peer reviewe

Measurement of the top quark mass using charged particles in pp collisions at root s=8 TeV

Peer reviewe

Measurement of the Splitting Function in &ITpp &ITand Pb-Pb Collisions at root&ITsNN&IT=5.02 TeV

Data from heavy ion collisions suggest that the evolution of a parton shower is modified by interactions with the color charges in the dense partonic medium created in these collisions, but it is not known where in the shower evolution the modifications occur. The momentum ratio of the two leading partons, resolved as subjets, provides information about the parton shower evolution. This substructure observable, known as the splitting function, reflects the process of a parton splitting into two other partons and has been measured for jets with transverse momentum between 140 and 500 GeV, in pp and PbPb collisions at a center-of-mass energy of 5.02 TeV per nucleon pair. In central PbPb collisions, the splitting function indicates a more unbalanced momentum ratio, compared to peripheral PbPb and pp collisions.. The measurements are compared to various predictions from event generators and analytical calculations.Peer reviewe