Tools to reduce the resistance to change in colombian smes

En Colombia más del 80% de las empresas se encuentran catalogadas como PYMES (pequeñas y medianas empresas), las cuales permanentemente reciben requerimientos por parte de entes gubernamentales, clientes o una parte del sector mismo en el que se desarrollan; cuando estas empresas carecen de orden o buena estructuración organizacional para la atención de estos, por lo que se encuentran enfrentadas a múltiples dificultades, entre las cuales se evidencia la resistencia al cambio, debido, a ser de fuerte impacto y cuenta con cierta dificultad para manejarla, conllevando a la pérdida de competitividad con las empresas o en el peor de los casos, su desaparición. Se efectuó una revisión literaria de conceptos relacionados sobre el tema mencionado, en las bases de datos Scielo, Dialnet, Redalyc, Emeralinsight y Google scholar. Así mismo, se identificaron seis herramientas principales, como son: evaluación del entorno, estructura organizacional, filosofía organizacional, la planeación estratégica, el liderazgo y la comunicación, que son consideradas de gran importancia en su aplicabilidad, acompañadas de una serie de actividades que mejorarán la efectividad en el uso de dichas herramientas y, por lo tanto, contribuirá al manejo de la resistencia al cambio de las PYMES en Colombia.In Colombia, more than 80% of companies are classified as SMEs (small and medium-size enterprises), which are permanently required by governmental bodies, clients or a part of the sector in which they develop; when these companies lack order or good organizational structure for their attention, so they are faced with multiple difficulties, between which is evidenced the resistance to the change, due to being of strong impact and with some difficulty to manage it, leading to the loss of competitiveness with the companies or in the worst case, its disappearance. In addition, six main tools were identified, such as: environmental assessment, organizational structure, organizational philosophy, strategic planning, leadership and communication, which are considered of great importance in their applicability, accompanied by a series of activities which will improve the effectiveness in the use of these tools and, will therefore contribute to the management of the resistance to change of SMEs in Colombia

La imagen como pensamiento

Este libro es resultado del 1er Foro Internacional de Estudios Visuales ‘La imagen como pensamiento’ que se llevó a cabo del 13 al 16 de octubre del año 2014 en la Facultad de Artes de la UAEMéx.RECURSOS DEL PIFI 2013. ADMINISTRACIÓN 2013-2017 DE LA FACULTAD DE ARTES DE LA UNIVERSIDAD AUTONÓMA DEL ESTADO DE MÉXIC

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements