9 research outputs found
Trusted Computing Strengthens Cloud Authentication
Cloud computing is a new generation of technology which is designed to provide the commercial necessities, solve the IT management issues, and run the appropriate applications. Another entry on the list of cloud functions which has been handled internally is Identity Access Management (IAM). Companies encounter IAM as security challenges while adopting more technologies became apparent. Trust Multi-tenancy and trusted computing based on a Trusted Platform Module (TPM) are great technologies for solving the trust and security concerns in the cloud identity environment. Single sign-on (SSO) and OpenID have been released to solve security and privacy problems for cloud identity. This paper proposes the use of trusted computing, Federated Identity Management, and OpenID Web SSO to solve identity theft in the cloud. Besides, this proposed model has been simulated in .Net environment. Security analyzing, simulation, and BLP confidential model are three ways to evaluate and analyze our proposed model
Histological study of the oral cavity of sea snake Hydrophis cyanocinctus in the coast of Minab, Oman sea
Sea snakes are the largest group of marine reptiles, but their role in the food chain in their habitats remains unknown. Histological studies of the oral cavity in sea snakes are essential to interpret food habits and to identify the structure of poison glands. The Present research is designed to study the Histology of the oral cavity in sea snake Hydrophis cyanocinctus. For this purpose, 6 individuals of sea snakes were collected from Minab, Hormozgan. Then the sections were taken from the Palate and floor of the mouth. Sections were stained by H&E and PAS, and observed with a light microscope. The results showed that the epithelium was keratinized, stratified squamous, and specialized. The lamina propria contained lymphoid tissue. In the submucosa, the nucleated RBC, Heterophil cells, and connective tissue cells were observed. The glandular tissue was serosal and the mucosal gland and the muscle layer were observed skeletal. Mucosal glands and some parts of epithelium were PAS-Positive. The results of this study showed that in spite of many similarities between the histological structures of H. cyanocinctus and other snakes and reptiles, some significant structural differences exist in which can be defined as a specific model for sea snakes
DNA damage response and breast cancer development: Possible therapeutic applications of ATR, ATM, PARP, BRCA1 inhibition
Breast cancer is the most common and significant cancers in females regarding the loss of life quality. Similar to other cancers, one of the etiologic factors in breast cancer is DNA damage. A plethora of molecules are responsible for sensing DNA damage and mediating actions which lead to DNA repair, senescence, cell cycle arrest and if damage is unbearable to apoptosis. In each of these, aberrations leading to unrepaired damage was resulted in uncontrolled proliferation and cancer. Another cellular function is autophagy defined as a process eliminating of unnecessary proteins in stress cases involved in pathogenesis of cancer. Knowing their role in cancer, scholars have tried to develop strategies in order to target DDR and autophagy. Further, the interactions of DDR and autophagy plus their regulatory role on each other have been focused simultaneously. The present review study has aimed to illustrate the importance of DDR and autophagy in breast cancer according to the related studies and uncover the relation between DDR and autophagy and its significance in breast cancer therapy.Depto. de InmunologĂa, OftalmologĂa y ORLFac. de MedicinaTRUEpu