Metformin prevents metabolic side effects during systemic glucocorticoid treatment

Swiss National Research Foundatio

Primordial magnetic fields and formation of molecular hydrogen

We study the implications of primordial magnetic fields for the thermal and ionization history of the post-recombination era. In particular we compute the effects of dissipation of primordial magnetic fields owing to ambipolar diffusion and decaying turbulence in the intergalactic medium (IGM) and the collapsing halos and compute the effects of the altered thermal and ionization history on the formation of molecular hydrogen. We show that, for magnetic field strengths in the range 2 \times 10^{-10} {\rm G} \la B_0 \la 2 \times 10^{-9} {\rm G}, the molecular hydrogen fraction in IGM and collapsing halo can increase by a factor 5 to 1000 over the case with no magnetic fields. We discuss the implication of the increased molecular hydrogen fraction on the radiative transfer of UV photons and the formation of first structures in the universe.Comment: 12 pages, 4 figures, accepted in MNRA

Interpretation, Evaluation and the Semantic Gap ... What if we Were on a Side-Track?

International audienceA significant amount of research in Document Image Analysis, and Machine Perception in general, relies on the extraction and analysis of signal cues with the goal of interpreting them into higher level information. This paper gives an overview on how this interpretation process is usually considered, and how the research communities proceed in evaluating existing approaches and methods developed for realizing these processes. Evaluation being an essential part to measuring the quality of research and assessing the progress of the state-of-the art, our work aims at showing that classical evaluation methods are not necessarily well suited for interpretation problems, or, at least, that they introduce a strong bias, not necessarily visible at first sight, and that new ways of comparing methods and measuring performance are necessary. It also shows that the infamous {\em Semantic Gap} seems to be an inherent and unavoidable part of the general interpretation process, especially when considered within the framework of traditional evaluation. The use of Formal Concept Analysis is put forward to leverage these limitations into a new tool to the analysis and comparison of interpretation contexts

Physical parameters for Orion KL from modelling its ISO high resolution far-IR CO line spectrum

As part of the first high resolution far-IR spectral survey of the Orion KL region (Lerate et al. 2006), we observed 20 CO emission lines with Jup=16 to Jup=39 (upper levels from approx 752 K to 4294 K above the ground state). Observations were taken using the Long Wavelength Spectrometer (LWS) on board the Infrared Space Observatory (ISO), in its high resolution Fabry-Perot (FP) mode (approx 33 km s$^{-1}$). We present here an analysis of the final calibrated CO data, performed with a more sophisticated modelling technique than hitherto, including a detailed analysis of the chemistry, and discuss similarities and differences with previous results. The inclusion of chemical modelling implies that atomic and molecular abundances are time-predicted by the chemistry. This provides one of the main differences with previous studies in which chemical abundances needed to be assumed as initial condition. The chemistry of the region is studied by simulating the conditions of the different known components of the KL region: chemical models for a hot core, a plateau and a ridge are coupled with an accelerated Lambda-iteration (ALI)radiative transfer model to predict line fluxes and profiles. We conclude that the CO transitions with 18<Jup<25 mainly arise from a hot core of diameter 0.02 pc and a density of 10$^{7}$ cm$^{-3}$ rather from the plateau as previous studies had indicated.Comment: The paper contains 10 pages, 7 figures and 4 tables. MNRAS accepte

Multi-messenger observations of a binary neutron star merger

On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta