1,581 research outputs found
Comparison of Sequential Three-Drug Regimens as Initial Therapy for HIV-1 Infection
- Author
- Publication venue
- Publication date
- 01/01/2003
- Field of study
BACKGROUND The optimal sequencing ofantiretroviral regimens for the treatment of infection with human immunodeficiency virus type 1 (HIV-1) is unknown. We compared several different antiretroviral treatment strategies. METHODS This multicenter, randomized, partially double-blind trial used a factorial design to compare pairs of sequential three-drug regimens, starting with a regimen including zidovudine and lamivudine or a regimen including didanosine and stavudine in combination with either nelfinavir or efavirenz. The primary end point was the length of time to the failure ofthe second three-drug regimen. RESULTS A total of 620 subjects who had not previously received antiretroviral therapy were followed for a median of 2. 3 years. Starting with a three-drug regimen containing efavirenz combined with zidovudine and lamivudine (but not efavirenz combined with didanosine and stavudine) appeared to delay the failure ofthe second regimen, as compared with starting with a regimen containing nelfinavir (hazard ratio for failure ofthe second regimen, 0.71; 95 percent confidence interval, 0.48 to 1.06), as well as to delay the second virologic failure (hazard ratio, 0.56; 95 percent confidence interval, 0.29 to 1.09), and significantly delayed the failure ofthe first regimen (hazard ratio, 0.39) and the firstvirologic failure (hazard ratio, 0.34). Starting with zidovudine and lamivudine combined with efavirenz (but not zidovudine and lamivudine combined with nelfinavir) appeared to delay the failure of the second regimen, as compared with starting with didanosine and stavudine (hazard ratio, 0.68), and significantly delayed both the first and the second virologic failures (hazard ratio for the firstvirologic failure, 0.39; hazard ratio for the second virologic failure, 0.47), as well as the failure ofthe first regimen (hazard ratio, 0.35). The initial use of zidovudine, lamivudine, and efavirenz resulted in a shorter time to viral suppression. CONCLUSIONS The efficacy ofantiretroviral drugs depends on how they are combined. The combination of zidovudine, lamivudine, and efavirenz is superior to the other antiretroviral regimens used as initial therapy in this study
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The human body at cellular resolution: the NIH Human Biomolecular Atlas Program
- Author
- Ahadi Sara
- Akoju Sushma A.
- Anderson James
- Ansong Charles
- Atkinson Mark
- Bahmani Amir
- Bar-Joseph Ziv
- Biancalani Tommaso
- Black Sarah
- Blood Philip D.
- Bodenmiller Bernd
- Brown Marishka
- Brusko Maigan
- Brusko Todd
- Burnum-Johnson Kristin E.
- Butler Andrew
- Börner Katy
- Cai Long
- Caprioli Richard M.
- Chou Peter
- Clare-Salzler Michael
- Conroy Richard
- Cross Leonard E.
- deCaestecker Mark
- Desai Tushar
- Dries Ruben
- Eraslan Gokcen
- Esplin Ed
- Fisher Eyal
- Fogo Agnes B.
- Friedman Samuel H.
- Gaffney Leslie
- Galis Zorina
- Galis Zorina S.
- Gehlenborg Nils
- Ghazanfar Shila
- Goldaracena Isabel
- Greenleaf William James
- Gutierrez Danielle
- Hagood James
- Harbury Pehr
- Harris Raymond
- Heiland Randy
- Herr Bruce
- Horning Aaron
- Hupalowska Anna
- Jackson Dana
- Jain Sanjay
- Jorgensen Marda
- Keays Maria
- Kharchenko Peter
- Kingsford Carl
- Kiselev Vladimir Yu.
- Kishi Jocelyn Y.
- Laskin Julia
- Lau Ken
- Lee Hayan
- Lenhardt W. Christopher
- Lin Shin
- Lin Yiing
- Ma Jian
- Mabee Paula
- Macklin Paul
- Maffioletti Sergio
- Marioni John
- McCallum Chuck
- Michailidis Stavros
- Mulye Jay
- Murphy Robert F.
- Nagendran Monica
- Neumann Elizabeth K.
- Nevins Stephanie A.
- Nick Harry
- Nolan Garry
- Nystrom Nicholas A.
- Otto Kevin
- Paten Benedict
- Patterson Nathan Heath
- Pawlyk Aaron
- Piehowski Paul D.
- Pillai Ajay
- Plevritis Sylvia
- Posgai Amanda
- Procaccini Dena
- Pryhuber Gloria
- Quardokus Ellen M.
- Record Lisel
- Regev Aviv
- Ricarte Allyson
- Robasky Kimberly
- Rood Jennifer
- Ropelewski Alexander J.
- Roy Ananda
- Roy Ananda L.
- Rozenblatt-Rosen Orit
- Ruffalo Matthew
- Saka Sinem K.
- Satija Rahul
- Schuerch Christian Martijn
- Scibek Robin M.
- Sechi Salvatore
- Shendure Jay
- Shirey William E.
- Silverstein Jonathan C.
- Sluka James P.
- Snyder Michael P.
- Spraggins Jeffrey M.
- Srinivas Pothur
- Stuart Tim
- Sun Xin
- Teichmann Sarah A.
- Trapnell Cole
- Vaishnav Eeshit D.
- van de Plas Raf
- Vella Margaret
- Venkataraaman Vishal Gautham
- Wang Yu
- Wasserfall Clive
- Weber Griffin M.
- Wilder Elizabeth
- Ye DongHye
- Yin Peng
- Yuan Guo-Cheng
- Zhang Kun
- Zhu Qian
- Zhu Ying
- Publication venue
- Nature
- Publication date
- 08/10/2020
- Field of study
Abstract: Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible three-dimensional molecular and cellular atlas of the human body, in health and under various disease conditions
Identification of a BRCA2-Specific modifier locus at 6p24 related to breast cancer risk
- Author
- Aalfs C. M.
- Aalfs Cora M.
- Adenis Claude
- Adlard Julian
- Adlard Julian
- Aittomäki Kristiina
- Alonso M. Rosario
- Altshuler David
- Andrulis Irene L.
- Antoniou Antonis C.
- Arason Adalgeir
- Ardern-Jones Audrey
- Arnold Norbert
- Attard Virginia
- Ausems M. G E M
- Ausems Margreet G E M
- Bacot Francois
- Baisch Christian
- Bancroft Elizabeth
- Bardsley Cathryn
- Barile Monica
- Barjhoux Laure
- Barjhoux Laure
- Barouk-Simonet Emmanuelle
- Barrowdale Daniel
- Barton David
- Barwell Julian
- Belotti Muriel
- Belotti Muriel
- Benitez Javier
- Berlin Cheryl
- Berthet Pascaline
- Bignon Yves Jean
- Blanco Ignacio
- Blok M. J.
- Bojesen Stig E.
- Bonadona Valérie
- Bonnet Françoise
- Bourdon Violaine
- Bradshaw Nicola
- Brady Angela
- Brauch Hiltrud
- Brenner Hermann
- Bressac-de-Paillerets Brigitte
- Brewer Carole
- Brice Glen
- Bronner Myriam
- Bruening Thomas
- Bubien Virginie
- Buecher Bruno
- Burwinkel Barbara
- Caldes Trinidad
- Caron Olivier
- Castro Elena
- Chang-Claude Jenny
- Chenevix-Trench Georgia
- Claber Oonagh
- Colas Chrystelle
- Cole Trevor
- Collier Rebecca
- Collée J. M.
- Cook Jackie
- Coron Fanny
- Couch Fergus J.
- Coulet Florence
- Coupier Isabelle
- Cox Angela
- Crawford Gillian
- D'Andrea Emma
- Damiola Francesca
- Damiola Francesca
- Davidson Rosemarie
- de Bock G. H.
- de Lange J. L.
- de Pauw Antoine
- Delnatte Capucine
- Demange Liliane
- Dennis Joe
- Devilee P.
- Devillee Peter
- Dicks Ed
- Domchek Susan M.
- Donaldson Alan
- Dorkins Huw
- Douglas Fiona
- Dreyfus Hélène
- Drummond Sarah
- Duncan Alexis
- Dunning Alison M.
- Durell Sarah
- Dörk Thilo
- Eason Jacqueline
- Easton Douglas F.
- Eccles Diana
- Eddy Charlotte
- Eeles Rosalind A.
- Eisinger François
- Eldridge Ronald C.
- Ellis Ian
- Ellis Steve
- Ellis Steve
- Evans D. Gareth
- Evans D. Gareth
- Faivre Laurence
- Fasching Peter A.
- Feillel Viviane
- Ferrer Sandra Fert
- Ferrer Sandra Fert
- Fineberg Elena
- Fineberg Elena
- Fischer Hand Peter
- Fournier Joëlle
- Fricker Jean Pierre
- Friedman Eitan
- Frost Debra
- Frost Debra
- Frénay Marc
- Garber Judith
- García-Closas Montserrat
- Gaudet Mia M.
- Gauthier-Villars Marion
- Genuardi Maurizio
- Gibson Sarah
- Giles Graham G.
- Gille J. J P
- Giraud Sophie
- Gladieff Laurence
- Goff Sheila
- Goldgar David E.
- Golmard Lisa
- González-Neira Anna
- Goodman Selina
- Greene Mark H.
- Gregory Helen
- Guimbaud Rosine
- Guénel Pascal
- Gómez-Garcia E. B.
- Haiman Christopher A.
- Hall Per
- Halliday Dorothy
- Handallou Sandrine
- Hansen Thomas V O
- Haque Eshika
- Hardouin Agnés
- Healey Sue
- Hill Kathryn
- Hodgson Shirley
- Hoffman Jonathan
- Hogervorst F. B L
- Hogervorst Frans B L
- Hooning M. J.
- Hooning Maartje J.
- Houdayer Claude
- Houghton Catherine
- Houlston Richard
- Humphreys Manjeet K.
- Izatt Louise
- Jacobs Chris
- Jacobs Chris
- Jakubowska Anna
- James Margaret
- Jeffers Lisa
- Jensen Uffe Birk
- Jobson Irene
- Kennedy M. John
- Kets C. M.
- Kets Carolien M.
- Kientz Caroline
- Killick Emma
- Kirchhoff Tomas
- Kivuva Emma
- Klein Robert J.
- Ko Yon Dschun
- Kohut Kelly
- Kuchenbaecker Karoline B.
- Kulkarni Anjana
- Lalloo Fiona
- Lambrechts Diether
- Langman Caroline
- Lasset Christine
- Lazaro Conxi
- Lebrun Marine
- Lee Andrew
- Lehmann Anna
- Lidereau Rosette
- Lochmann Magdalena
- Longmuir Mark
- Longy Michel
- Longy Michel
- Lucassen Anneke
- Lynch Henry T.
- Léone Mélanie
- Mai Phuong L.
- Male Alison
- Mannermaa Arto
- Manoukian Siranoush
- Margolin Sara
- Martin Sue
- Mazoyer Sylvie
- Mazoyer Sylvie
- McBride Donna
- McCann Emma
- McGuffog Lesley
- McLeod Diane
- Meijers-Heijboer H. E J
- Meindl Alfons
- Melville Athalie
- Mensenkamp A. R.
- Michailidou Kyriaki
- Miedzybrodzka Zosia
- Milne Roger L.
- Moncoutier Virginie
- Morrison Patrick
- Mortemousque Isabelle
- Mourits M. J.
- Muller Danièle
- Murday Victoria
- Murray Alexandra
- Nathanson Katherine L.
- Neuhausen Susan L.
- Nevanlinna Heli
- Noguchi Tetsuro
- Nogues Catherine
- Offit Kenneth
- Ong Kai ren
- Oosterwijk J. C.
- Orr Nick
- Osorio Ana
- Page Elizabeth
- Pankratz Vernon S.
- Paterson Joan
- Peock Susan
- Peock Susan
- Pesch Beate
- Peterlongo Paolo
- Peto Julian
- Peyrat Jean Philippe
- Peysselon Magalie
- Pfeiler Georg
- Pharoah Paul D P
- Piedmonte Marion
- Pita Guillermo
- Platte Radka
- Platte Radka
- Porteous Mary
- Porteous Mary E.
- Prieur Fabienne
- Pujol Pascal
- Quarrell Oliver
- Rabstein Sylvia
- Radice Paolo
- Rahman Nazneen
- Randhawa Kashmir
- Rea Gillian
- Rebischung Christine
- Remenieras Audrey
- Rennert Gad
- Robson Mark
- Rogers Mark T.
- Rookus M. A.
- Rouleau Etienne
- Révillion Françoise
- Sawyer Elinor J.
- Schmidt M. K.
- Schmidt Marjanka K.
- Schmutzler Rita K.
- Schoof Nils
- Searle Anne
- Serra-Feliu Gemma
- Sevenet Nicolas
- Seynaeve C.
- Shah Sohela
- Shanley Susan
- Side Lucy
- Simard Jacques
- Singer Christian F.
- Sinilnikova Olga
- Sinilnikova Olga M.
- Smalley Sarah
- Snadden Lesley
- Snyder Carrie L.
- Sobol Hagay
- Sokolowska Johanna
- Soubrier Florent
- Soucy Penny
- Southey Melissa C.
- Spickenheuer Anne
- Spurdle Amanda B.
- Stayner Barbara
- Stoppa-Lyonnet Dominique
- Stoppa-Lyonnet Dominique
- Sutter Christian
- Taylor Amy
- Taylor Jane
- Tessier Daniel C.
- Thomassen Mads
- Tirapo Carole
- Tischkowitz Marc
- Tischkowitz Marc
- Tobias Ed
- Tollenaar R. A.
- Toulas Christine
- Tripathi Vishakha
- Uhrhammer Nancy
- van Asperen C. J.
- van Cronenburg T. C T E F
- van den Ouweland A. M W
- van den Ouweland Ans M W
- van der Hout A. H.
- van der Hout Annemarie H.
- van der Luijt R. B.
- van Deurzen C. H M
- van Leeuwen F. E.
- van Os T. A M
- van Rensburg Elizabeth J.
- Vasen H. F.
- Vennin Philippe
- Verhoef S.
- Verny-Pierre Carole
- Vijai Joseph
- Vincent Daniel
- Vénat-Bouvet Laurence
- Waisfisz Q.
- Walker Lisa
- Wang Qin
- Wang Xianshu
- Wappenschmidt Barbara
- Watt Catherine
- Weitzel Jeffrey N.
- Wiggins Jennifer
- Wijnen J. T.
- Wijnen Juul T.
- Winchester Lizzie
- Winqvist Robert
- Publication venue
- Public Library of Science (PLoS)
- Publication date
- 01/01/2013
- Field of study
Common genetic variants contribute to the observed variation in breast cancer risk for BRCA2 mutation carriers; those known to date have all been found through population-based genome-wide association studies (GWAS). To comprehensively identify breast cancer risk modifying loci for BRCA2 mutation carriers, we conducted a deep replication of an ongoing GWAS discovery study. Using the ranked P-values of the breast cancer associations with the imputed genotype of 1.4 M SNPs, 19,029 SNPs were selected and designed for inclusion on a custom Illumina array that included a total of 211,155 SNPs as part of a multi-consortial project. DNA samples from 3,881 breast cancer affected and 4,330 unaffected BRCA2 mutation carriers from 47 studies belonging to the Consortium of Investigators of Modifiers of BRCA1/2 were genotyped and available for analysis. We replicated previously reported breast cancer susceptibility alleles in these BRCA2 mutation carriers and for several regions (including FGFR2, MAP3K1, CDKN2A/B, and PTHLH) identified SNPs that have stronger evidence of association than those previously published. We also identified a novel susceptibility allele at 6p24 that was inversely associated with risk in BRCA2 mutation carriers (rs9348512; per allele HR = 0.85, 95% CI 0.80-0.90, P = 3.9×10−8). This SNP was not associated with breast cancer risk either in the general population or in BRCA1 mutation carriers. The locus lies within a region containing TFAP2A, which encodes a transcriptional activation protein that interacts with several tumor suppressor genes. This report identifies the first breast cancer risk locus specific to a BRCA2 mutation background. This comprehensive update of novel and previously reported breast cancer susceptibility loci contributes to the establishment of a panel of SNPs that modify breast cancer risk in BRCA2 mutation carriers. This panel may have clinical utility for women with BRCA2 mutations weighing options for medical prevention of breast cancer
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
- Author
- Aalfs C.M. (Cora)
- Adenis C. (Claude)
- Adlard J.W. (Julian)
- Agata S. (Simona)
- Agnarsson B.A. (Bjarni)
- Aittomäki K. (Kristiina)
- Andersen M.K. (Mette)
- Andrulis I.L. (Irene)
- Angelakos M. (Maggie)
- Antoniou A.C. (Antonis)
- Ardern-Jones A. (Audrey)
- Ardnor C.E. (Christina Edwinsdotter)
- Arnold N. (Norbert)
- Arun B.K. (Banu)
- Arver B. (Brita Wasteson)
- Asperen C.J. (Christi) van
- Attard V. (Virginia)
- Ausems M.G.E.M. (Margreet)
- Bacot F. (Francois)
- Bae-Jump V.L. (Victoria L.)
- Balmana J. (Judith)
- Bancroft E.K. (Elizabeth)
- Bardsley C. (Cathryn)
- Barjhoux L. (Laure)
- Barkardottir R.B. (Rosa)
- Barouk-Simonet E. (Emmanuelle)
- Barrowdale D. (Daniel)
- Barton D.E. (David)
- Barwell J. (Julian)
- Beattie M.S. (Mary)
- Belotti M. (Muriel)
- Benítez J. (Javier)
- Berlin C. (Cheryl)
- Berthet P. (Pascaline)
- Bignon Y.-J. (Yves-Jean)
- Bignon Y.-J. (Yves-Jean)
- Blanco I. (Ignacio)
- Blank S.V. (Stephanie)
- Blok M.J. (Marinus)
- Bock G.H. (Geertruida) de
- Bonadona V. (Valérie)
- Bonnani B. (Bernardo)
- Bonnet F. (Françoise)
- Borg Å. (Åke)
- Bourdon V. (Violaine)
- Bradshaw N. (Nicola)
- Brady A.F. (Angela)
- Bressac-de Paillerets B. (Brigitte)
- Brewer C. (C.)
- Brewer C. (Carole)
- Brice G. (Glen)
- Bronner M. (Myriam)
- Brunet J. (Joan)
- Bubien V. (Virginie)
- Buecher B. (Bruno)
- Bustinza G.B.
- Buys S.S. (Saundra)
- Caldes T. (Trinidad)
- Calender A. (Alain)
- Caligo M.A. (Maria)
- Campbell I. (Ian)
- Caron O. (Olivier)
- Castera L. (Laurent)
- Castro E. (Elena)
- Chan S. (Salina)
- Chenevix-Trench G. (Georgia)
- Chiquette J. (Jocelyne)
- Chung W.K. (Wendy)
- Claber O. (Oonagh)
- Claes K. (Kathleen)
- Cohn D.E. (David)
- Colas C. (Chrystelle)
- Cole T.J. (Trevor)
- Collier R. (Rebecca)
- Collée J.M. (Margriet)
- Cook J. (Jackie)
- Coron F. (Fanny)
- Couch F.J. (Fergus)
- Coulet F. (Florence)
- Coupier I. (Isabelle)
- Crawford G. (Gabe)
- Cronenburg T.C.T.E.F. van
- Cunningham J. (Jane)
- Daly M.B. (Mary)
- Damiola F. (Francesca)
- Damiola F. (Francesca)
- Davidson R. (Rosemarie)
- Deissler H. (Helmut)
- Delnatte C.D. (Capucine)
- Demange L. (Liliane)
- Dennis J. (Joe)
- Deurzen C.H.M. (Carolien) van
- Devilee P. (Peter)
- Devilee P. (Peter)
- Dicks E. (Ed)
- Diez O. (Orland)
- Ding Y.C. (Yuan)
- Dite G.S. (Gillian)
- Ditsch N. (Nina)
- Domchek S.M. (Susan)
- Donaldson A. (Alan)
- Dorfling C.M. (Cecelia)
- Dorkins H. (Huw)
- Douglas F. (Fiona)
- Douglas F. (Fiona)
- Dreyfus H. (Hélène)
- Drummond S. (Sarah)
- Duncan A. (Alexis)
- Dunning A.M. (Alison)
- Durda K. (Katarzyna)
- Durell S. (Sarah)
- Durán M. (Mercedes)
- Eason J. (Jacqueline)
- Easton D.F. (Douglas)
- Eccles D. (Diana)
- Eddy C. (Charlotte)
- Eeles R. (Rosalind)
- Ehrencrona H. (Hans)
- Einbeigi Z. (Zakaria)
- Eisinger F. (François)
- Ejlertsen B. (Bent)
- Ellis I.O. (Ian)
- Ellis S. (Steve)
- Ellis S.D. (Steve)
- Emanuelsson M. (Monica)
- Engel C. (Christoph)
- Engert S. (Stefanie)
- Evans D.G. (Gareth)
- Ewart-Toland A. (Amanda)
- Faivre L. (Laurence)
- Feillel V. (Viviane)
- Ferrer S.F.
- Fineberg E. (Elena)
- Fineberg E. (Elena)
- Fink-Retter A. (Anneliese)
- Foretova L. (Lenka)
- Fournier J. (Joëlle)
- Fredericksen Z. (Zachary)
- Frenay M. (Marc)
- Fricker J.P. (Jean Pierre)
- Friebel M.O.W. (Mark )
- Friedlander M. (Michael)
- Friedman E. (Eitan)
- Frost D. (Debra)
- Gadzicki D. (Dorothea)
- Ganz P.A. (Patricia)
- Garber J.
- Gaudet M.M. (Mia)
- Gauthier-Villars M. (Marion)
- Gehrig P.A. (Paola A.)
- Gerdes A-M. (Anne-Marie)
- Gibson S. (Sarah)
- Gille J.J. (Johan)
- Giraud S. (Sophie)
- Gladieff L. (Laurence)
- Glendon G. (Gord)
- Godwin A.K. (Andrew)
- Goff S. (Sheila)
- Goldgar D. (David)
- Gomez Garcia E.B. (Encarna)
- Goodman S. (Selina)
- Greene M.H. (Mark)
- Gregory H. (Helen)
- Gronwald J. (Jacek)
- Gschwantler-Kaulich D. (Daphne)
- Guimbaud R. (Rosine)
- Gómez García E.B. (Encarna)
- Hall A.S. (Alistair)
- Halliday D. (Dorothy)
- Hamann U. (Ute)
- Handallou S. (Sandrine)
- Hansen T.V.O. (Thomas)
- Haque E. (Eshika)
- Harbst K. (Katja)
- Hardouin A. (Agnès)
- hardouin A. (Agnès)
- Hart S. (Stewart)
- Healey S. (Sue)
- Henriksson K. (Karin)
- Herzog J. (Josef)
- Hodgson S.V. (Shirley)
- Hoffman J. (Jonathan)
- Hogervorst F.B.L. (Frans)
- Hooning M.J. (Maartje)
- Houdayer C. (Claude)
- Houghton C. (Catherine)
- Houlston R. (Richard)
- Hout A.H. (Annemarie) van der
- Hoya M. (Miguel) de La
- Huo D. (Dezheng)
- Huzarski T. (Tomasz)
- Imyanitov E.N. (Evgeny)
- Izatt L. (Louise)
- Izatt L. (Louise)
- Jacobs C. (Chris)
- Jakubowska A. (Anna)
- James M. (Margaret)
- James P.A. (Paul )
- Janavicius R. (Ramunas)
- Jaworska K. (Katarzyna)
- Jeffers L. (Lisa)
- Jensen U.B.
- Jernström H. (H.)
- Jobson I. (Irene)
- John E.M. (Esther)
- Jønson L. (Lars)
- Karlan B.Y. (Beth)
- Karlsson P. (Per)
- Kast K. (Karin)
- Kauff N. (Noah)
- Kaufman B. (Bella)
- Kennedy M.J. (John)
- Kets C.M. (Marleen)
- Kientz C. (Caroline)
- Killick S.R.
- Kivuva E. (Emma)
- Kohut K. (Kelly)
- Kosel M. (Matthew)
- Kristoffersson U. (Ulf)
- Kruse T.A. (Torben)
- Kuchenbaecker K.B. (Karoline)
- Kulkarni A. (Anjana)
- Kwong A. (Ava)
- Laitman Y. (Yael)
- Lalloo F. (Fiona)
- Lange J.L. (J.) de
- Langman C. (Caroline)
- Lasa A. (Adriana)
- Lasset C. (Christine)
- Lebrun M. (Marine)
- Lee A. (Andrew)
- Leeuwen F.E. (Flora) van
- Leeuwen F.E. (Flora) van
- Lehmann A. (Anna)
- Lejbkowicz F. (Flavio)
- Leroux D. (Dominique)
- Lester K.J. (Kathryn)
- Lidereau R. (Rosette)
- Liedgren S. (Sigrun)
- Ligtenberg M.J. (Marjolijn)
- Liljegren A. (Annelie)
- Lindblom A. (Annika)
- Lindor N.M. (Noralane)
- Loman N. (Niklas)
- Longmuir M. (Mark)
- Longy M. (Michel)
- Loud J.T. (Jennifer)
- Lu K.H. (Karen)
- Lubinski J. (Jan)
- Lucassen A. (Anneke)
- Luijt R.B. (Rob) van der
- Lynch H. (Henry)
- Lázaro C. (Conxi)
- Léone M. (Mélanie)
- Mai P.L. (Phuong)
- Male A. (Alison)
- Manoukian S. (Siranoush)
- Martin S. (Sue)
- Maskiell J. (Judi)
- Mazoyer S. (Sylvie)
- Mazoyer S. (Sylvie)
- McBride D. (Donna)
- McCann E. (Emma)
- McGuffog L. (Lesley)
- McLeod D. (Diane)
- Meijers-Heijboer E.J. (Hanne)
- Meijers-Heijboer H. (Hanne)
- Meindl A. (Alfons)
- Melin B. (Beatrice)
- Melloni G. (Giulia)
- Melville S.A. (Scott)
- Mensenkamp A.R. (Arjen)
- Miedzybrodzka Z. (Zosia)
- Miron A. (Alexander)
- Moeller S.T. (Sanne Traasdahl)
- Moncoutier V. (Virginie)
- Montagna M. (Marco)
- Morrison P.J. (Patrick)
- Mortemousque I. (Isabelle)
- Mourits M.J. (Marjan)
- Muller D.W. (Danièle)
- Mulligan A.M. (Anna Marie)
- Muranen T.A. (Taru)
- Murday V. (Victoria)
- Murray A. (Alexandra)
- Murray A. (Anna)
- Narod S. (Steven)
- Nathanson K.L. (Katherine)
- Neuhausen S.L. (Susan)
- Nevanlinna H. (Heli)
- Niederacher D. (Dieter)
- Niedermayr E. (Eveline)
- Nielsen F.C. (Finn)
- Noguchi T. (Tetsuro)
- Nogues C. (Catherine)
- Nordling M. (Margareta)
- Offit K. (Kenneth)
- Olah E.
- Olopade O.I. (Olofunmilayo)
- Olsson H.
- Olswold C. (Curtis)
- Ong K.-R. (Kai-Ren)
- Oosterwijk J.C. (Jan)
- Orsulic S. (Sandra)
- Os T.A.M. (Theo) van
- Os T.A.M. (Theo) van
- Osorio A. (Ana)
- Ottini L. (Laura)
- Ouweland A.M.W. (Ans) van den
- Ozcelik H. (Hilmi)
- Page E. (Elizabeth)
- Pankratz V.S. (Shane)
- Papi L. (Laura)
- Pastinen T. (Tomi)
- Paterson J. (Joan)
- Pauw A. (Antoine) de
- Pedersen I.S. (Inge Sokilde)
- Peissel B. (Bernard)
- Pensotti V. (Valeria)
- Peock S. (Susan)
- Peterlongo P. (Paolo)
- Peyrat J.-P.
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- Phelan C. (Catherine)
- Piedmonte M. (Marion)
- Pigg M.H. (Maritta )
- Platte R. (Radka)
- Plendl H. (Hansjoerg)
- Porteous M.E. (Mary)
- Preisler-Adams S. (Sabine)
- Prieur F. (Fabienne)
- Pujana M.A. (Miguel)
- Pujol P. (Pascal)
- Quarrell O. (Oliver)
- Radice P. (Paolo)
- Rahman N. (Nazneen)
- Ramus S.J. (Susan)
- Randhawa K. (Kashmir)
- Rantala J. (Johanna)
- Rappaport C. (Christine)
- Rea D. (Dan)
- Rebbeck R. (Timothy)
- Rebischung C. (Christine)
- Remenieras A. (Audrey)
- Rennert G. (Gad)
- Rensburg E.J. (Elizabeth) van
- Rhiem K. (Kerstin)
- Robson M. (Mark)
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- Rogers M.T. (Mark)
- Romero A. (Alfonso)
- Rookus M.A. (M.)
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- Rosenquist R. (R.)
- Rouleau E. (Etienne)
- Révillion F. (Françoise)
- Sand S.R. (Sharon)
- Sarrel K. (Kara)
- Schmidt M.K. (Marjanka)
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- Serra-Feliu G. (Gemma)
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- Shanley S. (Susan)
- Shimon Paluch S. (Shani)
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- Simard J. (Jacques)
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- Slager S. (Susan)
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- Sobol H. (Hagay)
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- Soller M. (Maria)
- Soubrier F.
- Soucy P. (Penny)
- Southey M.C. (Melissa)
- Spurdle A.B. (Amanda)
- Stavropoulou A. (Alexandra)
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- Steele L. (Linda)
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- Sutter C. (Christian)
- Szabo C. (Csilla)
- Taylor A. (Amy)
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- Tea M.-K.
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- Tessier Y. (Yann)
- Teulé A. (A.)
- Thomassen M. (Mads)
- Thorne H. (Heather)
- Tibiletti M.G. (Maria Grazia)
- Tihomirova L. (Laima)
- Tirapo C. (Carole)
- Tischkowitz M. (Marc)
- Tobias E. (Ed)
- Tognazzo S. (Silvia)
- Tollenaar R.A.E.M. (Rob)
- Toulas C. (Christine)
- Tripathi V. (Vishakha)
- Tung N. (Nadine)
- Uhrhammer N. (Nancy)
- Varesco L. (Liliana)
- Varon-Mateeva R. (Raymonda)
- Vaszko T. (Tibor)
- Vennin P. (Philippe)
- Verhoef S.
- Verhoef S. (S.)
- Verny-Pierre C. (Carole)
- Viel A. (Alessandra)
- Vijai J. (Joseph)
- Vincent D. (Daniel)
- Volorio S. (Sara)
- Vénat-Bouvet L. (Laurence)
- Wachenfeldt A. (Anna) von
- Waisfisz Q. (Quinten)
- Walker L.J. (Lisa)
- Walsh C.S. (Christine)
- Wang C. (Chen)
- Wang X. (Xianshu)
- Wapenschmidt B. (Barbara)
- Watt C. (Catherine)
- Weaver J. (JoEllen)
- Weber B.H.F. (Bernhard)
- Weitzel J.N. (Jeffrey)
- Wiggins J. (Jennifer)
- Wijnen J.T. (Juul)
- Wijnen J.T. (Juul)
- Winchester L. (Lizzie)
- Yannoukakos D. (Drakoulis)
- Złowocka-Perłowska E. (Elzbieta)
- Öfverholm A. (Anna)
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 15/04/2013
- Field of study
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7×10-8, HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4×10-8, HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4×10-8, HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific associat
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers
- Author
- Aalfs Cora M.
- Aaltonen Kirsimari
- Adenis Claude
- Adlard Julian
- Agnarsson Bjarni A.
- Aittomäki Kristiina
- Alonso Rosario
- Amadori Alberto
- Andrulis Irene L.
- Angelakos Maggie
- Antoniou Antonis C.
- Ardern Jones Audrey
- Ardnor Christina Edwinsdotter
- Arnold Norbert
- Arun Banu K.
- Arver Brita
- Attard Virginia
- Ausems M. G. E. M.
- Balmaña J.
- Balogh Maria
- Bancroft Elizabeth
- Bardel Claire
- Bardsley Cathryn
- Barile Monica
- Barjhoux Laure
- Barouk Simonet Emmanuelle
- Barroso Alicia
- Barrowdale Daniel
- Barton David
- Barwell Julian
- Belotti Muriel
- Benitez Javier
- Berger Andreas
- Berlin Cheryl
- Berthet Pascaline
- Bignon Yves Jean
- Blanco Amie
- Blanco Ignacio
- Blein Sophie
- Blok M. J.
- Blomqvist Drs Carl
- Bonadona Valérie
- Bonanni Bernardo
- Bonnet Françoise
- Borg Ake
- Bourdon Violaine
- Bove Betsy
- Bozsik Aniko
- Bradshaw Nicola
- Brady Angela
- Breast Cancer Family Registry Null
- Bressac de Paillerets Brigitte
- Brewer Carole
- Brice Glen
- Bronner Myriam
- Bubien Virginie
- Buecher Bruno
- Bustinza Gisela Barbany
- Buys Saundra S.
- Caldes Trinidad
- Calender Alain
- Caligo Maria A.
- Capella Gabriel
- Capone Gabriele L.
- Caron Olivier
- Carter Jonathan
- Castro Elena
- Chan Salina
- Chenevix Trench Georgia
- Chung Wendy K.
- Claber Oonagh
- Claes Kathleen
- Colas Chrystelle
- Cole Trevor
- Collier Rebecca
- Collonge Rame Marie Agnès
- Collée J. M.
- Conejero Raquel Andrés
- Conrad Peggy
- Cook Jackie
- Corines Marina
- Coron Fanny
- Couch Fergus J.
- Coulet Florence
- Coupier Isabelle
- Cox David G.
- Craven Caroline
- Crawford Beth
- Crawford Gillian
- Damette Alexandre
- Damiola Francesca
- Danjean Vincent
- Davidson Rosemarie
- de Bock G. H.
- de la Hoya Miguel
- de Lange J. L.
- De Leeneer Kim
- de Pauw Antoine
- Del Valle Jesús
- Delatycki Martin
- della Puppa Lara
- Delnatte Capucine
- Demange Liliane
- Dennis Joe
- Devilee Peter
- Diez Orland
- Ding Chun
- Ding Yuan Chun
- Dishon Sara
- Disilvestro Paul A.
- Dite Gillian
- Ditsch Nina
- Dolcetti Riccardo
- Domchek Susan M.
- Domokos Gabriella
- Donaldson Alan
- Dorfling Cecilia M.
- Dorkins Huw
- Douglas Fiona
- Dreyfus Hélène
- Driessen Rebecca
- Drummond Sarah
- Dumont Martine
- Duncan Alexis
- Durda Katarzyna
- Durell Sarah
- Eason Jacqueline
- Easton Douglas F.
- Eccles Diana
- Eddy Charlotte
- Eeles Ros
- Eglitis Drs Janis
- Ehrencrona Hans
- Einbeigi Zakaria
- Eisinger François
- Ejlertsen Bent
- Ellis Ian
- Ellis Steve
- Emanuelsson Monica
- Embrace Null
- Engel Christoph
- Erkkilä Irja
- Evans D. Gareth
- Faivre Laurence
- Feillel Viviane
- Ferenczi Judit
- Ferrer Sandra Fert
- Fineberg Elena
- Fink Retter Anneliese
- Foo Claire
- Foretova Lenka
- Foulkes William
- Fournier Joëlle
- Franko Judit
- Fricker Jean Pierre
- Friedman Eitan
- Frost Debra
- Frénay Marc
- Garber Judy
- Gauthier Villars Marion
- Gayther Simon
- Gehrig Andrea
- Gerdes Anne Marie
- Gibson Sarah
- Gille J. J. P.
- Giraud Sophie
- Gladieff Laurence
- Glendon Gord
- Godwin Andrew K.
- Goff Sheila
- Goldgar David E.
- Golmard Lisa
- Goodman Selina
- Greene Mark H.
- Gregory Helen
- Griškevicius Laimonas
- Gronwald Jacek
- Guimbaud Rosine
- Gómez Garcia E. B.
- Halliday Dorothy
- Hamann Ute
- Handallou Sandrine
- Hansen Thomas V. O.
- Haque Eshika
- Harbst Katja
- Hardouin Agnès
- Harrington Patricia
- Harris Marion
- Healey Sue
- Henriksson Karin
- Hill Kathryn
- Hodgson Shirley
- Hoffman Jonathan
- Hogervorst Frans B. L.
- Hooning M. J.
- Houdayer Claude
- Houghton Catherine
- Houlston Richard
- Imyanitov Evgeny N.
- Isaacs Claudine
- Izatt Louise
- Jacobs Chris
- Jacobs Lauren
- Jager Agnes
- Jakubowska Anna
- James Margaret
- Janavicius Ramunas
- Jaworska Bieniek Katarzyna
- Jeffers Lisa
- Jensen Uffe Birk
- Jernström Helena
- Jobson Irene
- Karlan Beth Y.
- Karlsson Per
- Kast Karin
- Kaulich Daphne Geschwantler
- Kennedy M. John
- Kets Carolien M.
- Kientz Caroline
- Killick Emma
- Kivuva Emma
- Kleibl Zdenek
- Kohut Kelly
- Konstantopoulou Irene
- Krilova Anna
- Kristoffersson Ulf
- Kruse Torben A.
- Kuchenbaecker Karoline B.
- Kulkarni Anjana
- Kwan Lorna
- Laitman Yael
- Lalloo Fiona
- Lambo Rossana
- Langman Caroline
- Lasset Christine
- Lazaro Conxi
- Lebrun Marine
- Lee Andrew
- Lee Robin
- Lefol Cédrick
- Lehmann Anna
- Lejbkowicz Flavio
- Leroux Dominique
- Lester Jenny
- Lidereau Rosette
- Liedgren Sigrun
- Liljegren Annelie
- Lincoln Anne
- Lindblom Annika
- Lindeman Geoffrey
- Lindor Noralane M.
- Loman Niklas
- Longmuir Mark
- Longy Michel
- Loranger Kate
- Lubinski Jan
- Lucassen Anneke
- Lynch Henry T.
- Léone Mélanie
- Machackova Eva
- Mai Phuong L.
- Mak Julie
- Male Alison
- Manoukian Siranoush
- Markov Nadja Bogdanova
- Martayan Aline
- Martin Sue
- Maskiell Judi
- Maugard Christine
- Mazoyer Sylvie
- Mcbride Donna
- Mccann Emma
- Mcguffog Lesley
- Mcleod Diane
- Meijers Heijboer Hanne E. J.
- Meindl Alfons
- Melin Beatrice
- Mensenkamp A. R.
- Miedzybrodzka Zosia
- Mitchell Gillian
- Moncoutier Virginie
- Montagna Marco
- Morrison Patrick J.
- Mortemousque Isabelle
- Mourits M. J.
- Muller Danièle
- Mulligan Anna Marie
- Muranen Taru A.
- Murday Victoria
- Murray Alexandra
- Nathanson Katherine L.
- Neuhausen Susan L.
- Nevanlinna Heli
- Niederacher Dieter
- Niedermayr Eveline
- Nielsen Finn C.
- Niu Qun
- Noguchi Tetsuro
- Nogues Catherine
- Nordling Margareta
- Nussbaum Robert L.
- O'Conor Michelle
- Obdeijn I. M.
- Offit Kenneth
- Olah Edith
- Olopade Olufunmilayo I.
- Olsson Håkan
- Olswold Curtis
- Ong Kai Ren
- Oosterwijk Jan C.
- Orsulic Sandra
- Osorio Ana
- OTTINI LAURA
- Overbeek L. I. H.
- Page Elizabeth
- Palola Virpi
- Pankratz Vernon S.
- Papi Laura
- Papp Janos
- Paterson Joan
- Pedersen Inge Sokilde
- Peissel Bernard
- Peixoto Ana
- Pensotti Valeria
- Peterlongo Paolo
- Peyrat Jean Philippe
- Peysselon Magalie
- Pfeiler Georg
- Pharoah Paul D. P.
- Phelan Catherine M.
- Piedmonte Marion
- Pigg Maritta Hellström
- Pilato Brunella
- Pinchev Mila
- Pinto Pedro
- Pita Guillermo
- Platte Radka
- Plendl Hansjoerg
- Pocza Timea
- Pohlreich Petr
- Porteous Mary E.
- Preisler Adams Sabine
- Prieur Fabienne
- Pujol Pascal
- Pye Carole
- Quarrell Oliver
- Radice Paolo
- Rahman Nazneen
- Ramus Susan J.
- Rantala Johanna
- Rappaport Christine
- Rea Gillian
- Rebbeck Timothy R.
- Rebischung Christine
- Remenieras Audrey
- Rennert Gad
- Rhiem Kerstin
- Robson Mark
- Rocha Patrícia
- Rogers Mark T.
- Rookus Matti A.
- Rosenquist Richard
- Rouleau Etienne
- Rudaitis Vilius
- Révillion Françoise
- Santos Catarina
- Sawyer Sarah
- Schmidt M. K.
- Schmutzler Rita K.
- Scuvera Giulietta
- Searle Anne
- Segota Ena
- Seldon Joyce
- Senter Leigha
- Serra Feliu Gemma
- Sevenet Nicolas
- Seynaeve C.
- Shanley Susan
- Side Lucy E.
- Siesling S.
- Simard Jacques
- Singer Christian F.
- Sinilnikova Olga M.
- Smalley Sarah
- Snadden Lesley
- Snyder Carrie L.
- Sobol Hagay
- Sokolowska Johanna
- Soller Maria
- Sornin Valérie
- Soubrier Florent
- Soucy Penny
- Spurdle Amanda B.
- Stayner Barbara
- Steele Linda
- Steinemann Doris
- Stengrevics Aivars
- Stenmark Askmalm Marie
- Stewart Nicola
- Stoppa Lyonnet Dominique
- Sukiennicki Grzegorz
- Sutter Christian
- Sweet Kevin
- Szabo Csilla I.
- Taylor Amy
- Taylor Jane
- Tchatchou Sandrine
- Tea Muy Kheng
- Teixeira Manuel R.
- Terry Mary Beth
- Teulé Alex
- Thelander Margo
- Thomas Gilles
- Thomassen Mads
- Thompson Ella
- Thorne Heather
- Tibiletti Maria Grazia
- Tihomirova Laima
- Tirapo Carole
- Tischkowitz Marc
- Tobias Ed
- Toland Amanda Ewart
- Tollenaar R. A. E. M.
- Tommasi Stefania
- Toulas Christine
- Tranchant Martine
- Tripathi Vishakha
- Tsimiklis Helen
- Tung Nadine
- Uhrhammer Nancy
- van Asperen C. J.
- van Cronenburg T. C. T. E. F.
- van den Ouweland Ans M. W.
- van der Hout A. H.
- van der Luijt Rob B.
- van Deurzen C. H. M.
- Van Le Linda
- van Leeuwen Flora E.
- van Os T. A. M.
- van Rensburg Elizabeth J.
- van Roozendaal Kees E. P.
- Varesco Liliana
- Varon Mateeva Raymonda
- Vasen H. F.
- Vaszko Tibor
- Vennin Philippe
- Verhoef S.
- Verny Pierre Carole
- Viel Alessandra
- Vijai Joseph
- von Wachenfeldt Anna
- Vénat Bouvet Laurence
- Waisfisz Q.
- Walker Lisa
- Wang Gohrke Shan
- Wappenschmidt Barbara
- Watt Catherine
- Weaver Jo Ellen
- Weitzel Jeffrey N.
- Wiggins Jennifer
- Wijnands R.
- Wijnen J. T.
- Winchester Lizzie
- Wozniak Eva
- Yannoukakos Drakoulis
- Zaffaroni Daniela
- Zidan Jamal
- Zikan Michal
- Zvocec Cecilia
- Öfverholm Anna
- Publication venue
- Publication date
- 01/01/2015
- Field of study
Introduction: Individuals carrying pathogenic mutations in the BRCA1 and BRCA2 genes have a high lifetime risk of breast cancer. BRCA1 and BRCA2 are involved in DNA double-strand break repair, DNA alterations that can be caused by exposure to reactive oxygen species, a main source of which are mitochondria. Mitochondrial genome variations affect electron transport chain efficiency and reactive oxygen species production. Individuals with different mitochondrial haplogroups differ in their metabolism and sensitivity to oxidative stress. Variability in mitochondrial genetic background can alter reactive oxygen species production, leading to cancer risk. In the present study, we tested the hypothesis that mitochondrial haplogroups modify breast cancer risk in BRCA1/2 mutation carriers. Methods: We genotyped 22,214 (11,421 affected, 10,793 unaffected) mutation carriers belonging to the Consortium of Investigators of Modifiers of BRCA1/2 for 129 mitochondrial polymorphisms using the iCOGS array. Haplogroup inference and association detection were performed using a phylogenetic approach. ALTree was applied to explore the reference mitochondrial evolutionary tree and detect subclades enriched in affected or unaffected individuals. Results: We discovered that subclade T1a1 was depleted in affected BRCA2 mutation carriers compared with the rest of clade T (hazard ratio (HR) = 0.55; 95% confidence interval (CI), 0.34 to 0.88; P = 0.01). Compared with the most frequent haplogroup in the general population (that is, H and T clades), the T1a1 haplogroup has a HR of 0.62 (95% CI, 0.40 to 0.95; P = 0.03). We also identified three potential susceptibility loci, including G13708A/rs28359178, which has demonstrated an inverse association with familial breast cancer risk. Conclusions: This study illustrates how original approaches such as the phylogeny-based method we used can empower classical molecular epidemiological studies aimed at identifying association or risk modification effects.Peer reviewe
The genetic architecture of the human cerebral cortex
- Author
- Adams Hieab H H
- Adams Hieab H H
- Agartz Ingrid
- Ahlijanian Michael
- Ahmad Shahzad
- Ainscough Susan
- Aisen Paul
- Albers Colleen S
- Albert Marilyn
- Alhusaini Saud
- Allard Joanne
- Almeida Marcio A A
- Alnæs Dag
- Alvim Marina K M
- Ames David
- Ames David
- Amin Najaf
- Amlien Inge K
- Amouyel Philippe
- Ances Beau
- Anderson Karen
- Anderson Tim J
- Andersson Micael
- Andreassen Ole A
- Andreassen Ole A
- Apostolova Liana
- Ard Tyler
- Arias-Vasquez Alejandro
- Armstrong Nicola J
- Armstrong Nicola J
- Arnedo Vanessa
- Arnold Steven E
- Artiges Eric
- Artiges Eric
- Ashley-Koch Allison
- Assaly Michele
- Assareh Amelia A
- Asthana Sanjay
- Atkins Joshua R
- Aydin Semiha
- Ayesa-Arriola Rosa
- Baca Marne
- Bachman David
- Banaschewski Tobias
- Barbot Alexis
- Barker Gareth
- Barone Paolo
- Bartha Rob
- Bartzokis George
- Bastin Mark E
- Bastin Mark E
- Bates Vernice
- Baune Bernhard T
- Becerra Mauricio
- Becker Andreas
- Becker James T
- Beckett Laurel
- Beckham Jean C
- Beiser Alexa S
- Belden Christine M
- Belger Aysenil
- Bell Karen L
- Berg Daniela
- Bergman Howard
- Bernard Manon
- Bernard Manon
- Bernick Charles
- Bernstein Matthew
- Beyer Frauke
- Bezivin-Frere Pauline
- Biondo Francesca
- Bis Joshua C
- Bis Joshua C
- Bishop Courtney
- Black Sandra
- Blangero John
- Blank Karen
- Bodge Courtney
- Bokde Arun
- Bonakdarpour Borna
- Boomsma Dorret I
- Borges-Neto Salvador
- Borowski Bret
- Borrie Michael
- Bralten Janita
- Brand Connie
- Brandabur Melanie
- Brandt Christine L
- Brewer James
- Brockington John
- Brodaty Henry
- Brodaty Henry
- Bromberg Uli
- Brooks David
- Brooks William M
- Brosch Jared R
- Brouwer Rachel M
- Brown Gregory G
- Bruehl Ruediger
- Brunner Han G
- Buckholtz Neil
- Buckner Randy L
- Budson Andrew E
- Buimer Elizabeth E L
- Buitelaar Jan K
- Burke Anna
- Burns Jeffrey M
- Bustillo Juan R
- Bülow Robin
- Bülow Robin
- Bürger Christian
- Bÿchel Christian
- Cabrera Yuliana
- Cahn Wiepke
- Cairns Murray J
- Cairns Nigel J
- Calhoun Vince
- Cannon Dara M
- Capote Horacio
- Carlsson Cynthia M
- Carmichael Owen
- Carr Vaughan J
- Carrillo Maria
- Carroll Maria
- Carson Richard E
- Carter Raina
- Casaceli Cynthia
- Casalin Paola
- Caseras Xavier
- Caspell Chelsea
- Caspers Svenja
- Catafau Ana
- Cavalleri Gianpiero L
- Cedarbaum Jesse
- Cellar Janet S
- Celmins Dzintra
- Cendes Fernando
- Chahine Lama
- Chakravarty Mallar
- Chalker Alison
- Chao Steven
- Chen Kewei
- Chen Qiang
- Chertkow Howard
- Cheung Joshua W
- Chiang Gloria
- Ching Christopher R K
- Chowdhury Munir
- Chowdhury Sohini
- Chu Congying
- Cichon Sven
- Clark Christopher M
- Clark David
- Coffey Christopher
- Coleman Edward
- Colodro-Conde Lucía
- Comery Thomas
- Conrad Gary
- Conrod Patricia
- Consortium CHARGE
- Consortium Enhancing NeuroImaging Genetics through Meta-Analysis
- Consortium EPIGEN
- Consortium IMAGEN
- Consortium SYS
- Correia Stephen
- Corvin Aiden
- Couvy-Duchesne Baptiste
- Crawford Karen
- Creech Mary L
- Crespo-Facorro Benedicto
- Crivello Fabrice
- Curran Joanne E
- D'Agostino Daniel
- Daedelow Laura
- Daiello Lori A
- Dale Anders M
- Dale Anders M
- Dalley Jeffrey
- Dalrymple-Alford John C
- Dalvie Shareefa
- Dang Mimi
- Dannlowski Udo
- Darin Abigail
- Davies Gareth E
- Davies Peter
- de Araujo Tânia K
- de Geus Eco J C
- de Zubicaray Greig I
- de Zwarte Sonja M C
- Deary Ian J
- Deary Ian J
- Debette Stephanie
- Debette Stephanie
- Decarli Charles
- DeCarli Charles
- Deeley Cheryl
- Degenhardt Franziska
- Delanty Norman
- DeMarco Kathryn
- den Braber Anouk
- Dennis Michelle F
- Depondt Chantal
- Desrivieres Sylvane
- Desrivières Sylvane
- Dietsche Bruno
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- Gaikwad Mrunalini
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- Ikeda Masashi
- Ikram M Arfan
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- Ing Alex
- Initiative Alzheimer’s Disease Neuroimaging
- Initiative Parkinson’s Progression Markers
- Iranzo Alex
- Isaacson Stuart
- Isensee Corinna
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- Ittermann Bernd
- Jack Clifford R
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- Jagust William
- Jahanshad Neda
- James Angela
- James Olga
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- Jang MiHyun
- Jankovic Joseph
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- Jennings Danna
- Jernigan Terry L
- Jia Tianye
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- Jian Xueqiu
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- Jicha Greg
- Jimenez Gustavo
- Jockwitz Christiane
- Johnson Kathleen
- Johnson Keith A
- Johnson Kris
- Johnson Nancy
- Johnson Patricia Lynn
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- Kataki Maria
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- Kaye Jeffrey A
- Kelly Sinead
- Keltz Melanie
- Kennedy Martin A
- Kertesz Andrew
- Kerwin Diana
- Khachaturian Zaven
- Kieburtz Karl
- Kielb Stephanie
- Kikuchi Masataka
- Killiany Ronald
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- Knapp Michael
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- Koleva Hristina
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- Koops Sanne
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- Krämer Bernd
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- Lee Virginia
- Lemaitre Hervé
- Lenahan Art
- Leonard Gabriel
- Lerner Alan
- Lethbridge Emma
- Lett Tristram A
- Leverenz James
- Levey Allan I
- Lewis Lindsay
- Lewis Lindsay B
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- Meyer-Lindenberg Andreas
- Michie Patricia T
- Milaneschi Yuri
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- Miller Delwyn D
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- Mirza-Schreiber Nazanin
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- Mühleisen Thomas W
- Müller-Myhsok Bertram
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- Nakahara Soichiro
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- van Eijk Liza
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- van Rooij Daan
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- Vanderswag Helen
- Varma Pradeep
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- Vemuri Prashanthi
- Venkov Heli
- Verhoef Ellen
- Vernooij Meike W
- Villena Teresa
- Villringer Arno
- Voyvodic James T
- Völker Uwe
- Völzke Henry
- Walter Henrik
- Walter Henrik
- Walter Sarah
- Walton Esther
- Wang Mingyuan
- Wang Yunpeng
- Ward Chad
- Wardlaw Joanna M
- Wardlaw Joanna M
- Weber Bernd
- Weinberger Daniel R
- Weiner Michael
- Weiner Michael W
- Weintraub Sandra
- Wen Wei
- Wen Wei
- Westlye Lars T
- Whelan Christopher D
- Whelan Robert
- Whelan Robert
- White Tonya
- Willeke Diana
- Williams Karen
- Williams Steve
- Wilson Renee
- Winkfield David
- Witbracht Megan
- Witt Stephanie H
- Witte A Veronica
- Wittfeld Katharina
- Wittfeld Katharina
- Wolf Christiane
- Wolfers Thomas
- Wolk David A
- Womack Kyle
- Wong Terence Z
- Woo Ellen
- Wright Margaret J
- Wright Margaret J
- Wu Chuang-Kuo
- Wu Jing Qin
- Wurster Isabel
- Xia Rui
- Yamamori Hidenaga
- Yanez Beatriz
- Yang Mia
- Yang Qiong
- Yang Qiong
- Yankey Jon
- Yasuda Clarissa L
- Yeh Randy
- Yesavage Jerome
- Zamrini Edward
- Zare Habil
- Zaremba Dario
- Zhang Zuo
- Zhou Juan
- Zhu Alyssa H
- Zimmerman Earl A
- Ziolkowski Jaimie
- Zsembik Leo C P
- Zwiers Marcel P
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2020
- Field of study
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder
The Science Performance of JWST as Characterized in Commissioning
- Author
- Abell Jim
- Abney Faith
- Abul-Huda Yasin
- Acton D. Scott
- Adams Evan
- Adler David
- Aguilar Jonathan
- Ahmed Nasif
- Alarcon Rafael Ramos
- Albert Loïc
- Alberts Stacey
- Aldridge David
- Allen Marsha
- Altenburg Martin
- Alvarez Jose Lorenzo
- Andersen Greg
- Anderson Harry
- Anderson Sara
- Argyriou Ioannis
- Armstrong Amber
- Arribas Santiago
- Artigau Etienne
- Arvai Amanda
- Atkinson Charles
- Bacon Gregory
- Bair Thomas
- Banks Kimberly
- Barrientes Jaclyn
- Barringer Bruce
- Bartosik Peter
- Bast William
- Baudoz Pierre
- Beatty Thomas
- Bechtold Katie
- Beck Tracy
- Bergeron Eddie
- Bergkoetter Matthew
- Bhatawdekar Rachana
- Birkmann Stephan
- Blazek Ronald
- Blome Claire
- Boccaletti Anthony
- Boeker Torsten
- Boia John
- Bonaventura Nina
- Bond Nicholas
- Bosley Kari
- Boucarut Ray
- Bourque Matthew
- Bouwman Jeroen
- Bower Gary
- Bowers Charles
- Boyer Martha
- Bradley Larry
- Brady Greg
- Braun Hannah
- Breda David
- Bresnahan Pamela
- Bright Stacey
- Britt Christopher
- Bromenschenkel Asa
- Brooks Brian
- Brooks Keira
- Brown Bob
- Brown Matthew
- Brown Patricia
- Bunker Andy
- Burger Matthew
- Bushouse Howard
- Cale Steven
- Cameron Alex
- Cameron Peter
- Canipe Alicia
- Caplinger James
- Caputo Francis
- Cara Mihai
- Carey Larkin
- Carniani Stefano
- Carrasquilla Maria
- Carruthers Margaret
- Case Michael
- Catherine Riggs
- Chance Don
- Chapman George
- Charlot Stéphane
- Charlow Brian
- Chayer Pierre
- Chen Bin
- Cherinka Brian
- Chichester Sarah
- Chilton Zack
- Chonis Taylor
- Clampin Mark
- Clark Charles
- Clark Kerry
- Coe Dan
- Coleman Benee
- Colon Knicole
- Comber Brian
- Comeau Tom
- Connolly Dennis
- Cooper James
- Cooper Rachel
- Coppock Eric
- Correnti Matteo
- Cossou Christophe
- Coulais Alain
- Coyle Laura
- Cracraft Misty
- Curti Mirko
- Cuturic Steven
- Davis Katherine
- Davis Michael
- de Oliveira Catarina Alves
- Dean Bruce
- Del Pino Bruno Rodriguez
- DeLisa Amy
- deMeester Wim
- Dencheva Nadezhda
- Dencheva Nadia
- DePasquale Joseph
- Deschenes Jeremy
- Detre Örs Hunor
- Diaz Rosa
- Dicken Dan
- DiFelice Audrey
- Dillman Matthew
- Dixon William
- Doggett Jesse
- Donaldson Tom
- Douglas Rob
- Doyon René
- DuPrie Kimberly
- Dupuis Jean
- Durning John
- Easmin Nilufar
- Eck Weston
- Edeani Chinwe
- Egami Eiichi
- Ehrenwinkler Ralf
- Eisenhamer Jonathan
- Eisenhower Michael
- Elie Michelle
- Elliott James
- Elliott Kyle
- Ellis Tracy
- Engesser Michael
- Espinoza Nestor
- Etienne Odessa
- Etxaluze Mireya
- Falini Patrick
- Feeney Matthew
- Feinberg Lee
- Ferruit Pierre
- Ferry Malcolm
- Filippazzo Joseph
- Fincham Brian
- Fix Mees
- Flagey Nicolas
- Florian Michael
- Flynn Jim
- Fontanella Erin
- Ford Terrance
- Forshay Peter
- Fox Ori
- Franz David
- Friedman Scott
- Fu Henry
- Fullerton Alexander
- Galkin Sergey
- Galyer Anthony
- Gardner Jonathan
- Gardner Lisa
- Garland Dennis
- Garrett Bruce
- Gasman Danny
- Gaspar Andras
- Gaudreau Daniel
- Gauthier Peter
- Geers Vincent
- Geithner Paul
- Gennaro Mario
- Giardino Giovanna
- Girard Julien
- Giuliano Mark
- Glasse Alistair
- Glassmire Kirk
- Glauser Adrian
- Glazer Stuart
- Godfrey John
- Golimowski David
- Gollnitz David
- Gong Fan
- Gonzaga Shireen
- Gordon Karl
- Gordon Michael
- Goudfrooij Paul
- Greene Thomas
- Greenhouse Matthew
- Grimaldi Stefano
- Groebner Andrew
- Grundy Timothy
- Guillard Pierre
- Gutman Irvin
- Ha Kong Q.
- Haderlein Peter
- Hagedorn Andria
- Hainline Kevin
- Haley Craig
- Hami Maryam
- Hamilton Forrest
- Hammel Heidi
- Hansen Carl
- Harkins Tom
- Harr Michael
- Hart Jessica
- Hart Quyen
- Hartig George
- Hashimoto Ryan
- Haskins Sujee
- Hathaway William
- Havey Keith
- Hayden Brian
- Hecht Karen
- Heller-Boyer Chris
- Henriques Caroline
- Henry Alaina
- Hermann Karl
- Hernandez Scarlin
- Hesman Brigette
- Hicks Brian
- Hilbert Bryan
- Hines Dean
- Hoffman Melissa
- Holfeltz Sherie
- Holler Bryan J.
- Hoppa Jennifer
- Hott Kyle
- Howard Joseph
- Howard Rick
- Hunter Alexander
- Hunter David
- Hurst Brendan
- Husemann Bernd
- Hustak Leah
- Ignat Luminita Ilinca
- Illingworth Garth
- Irish Sandra
- Jackson Wallace
- Jahromi Amir
- Jakobsen Peter
- James Bryan
- James LeAndrea
- Januszewski William
- Jenkins Ann
- Jirdeh Hussein
- Johnson Phillip
- Johnson Timothy
- Jones Danny
- Jones Olivia
- Jones Ron
- Jones Vicki
- Jordan Ian
- Jordan Margaret
- Jurczyk Sarah
- Jurling Alden
- Kaleida Catherine
- Kalmanson Phillip
- Kammerer Jens
- Kang Huijo
- Kao Shaw-Hong
- Karakla Diane
- Kavanagh Patrick
- Kelly Doug
- Kendrew Sarah
- Kennedy Herbert
- Kenny Deborah
- Keski-kuha Ritva
- Keyes Charles
- Kidwell Richard
- Kimble Randy
- Kinzel Wayne
- Kirk Jeff
- Kirkpatrick Mark
- Kirshenblat Danielle
- Klaassen Pamela
- Knapp Bryan
- Knight J. Scott
- Knollenberg Perry
- Koehler Robert
- Koekemoer Anton
- Kovacs Aiden
- Kulp Trey
- Kumari Nimisha
- Kyprianou Mark
- La Massa Stephanie
- Labador Aurora
- Lagage Pierre-Olivier
- Lajoie Charles-Phillipe
- Lallo Matt
- Lallo Matthew
- Lam May
- Lamb Tracy
- Lambros Scott
- Lampenfield Richard
- Langston James
- Larson Kirsten
- Law David
- Lawrence Jon
- Lee David
- Leisenring Jarron
- Lepo Kelly
- Leveille Michael
- Levenson Nancy
- Levine Marie
- Levy Zena
- Lewis Dan
- Lewis Hannah
- Libralato Mattia
- Lightsey Paul
- Link Miranda
- Liu Lily
- Lo Amy
- Lockwood Alexandra
- Logue Ryan
- Long Chris
- Long Douglas
- Loomis Charles
- Lopez-Caniego Marcos
- Love-Pruitt Jennifer
- Lucy Adrian
- Luetzgendorf Nora
- Maghami Peiman
- Maiolino Roberto
- Major Melissa
- Malla Sunita
- Malumuth Eliot
- Manjavacas Elena
- Mannfolk Crystal
- Marin Macarena Garcia
- Marquez Javier Alvarez
- Marrione Amanda
- Marston Anthony
- Martel André
- Maschmann Marc
- Masci Gregory
- Masciarelli Michaela
- Maszkiewicz Michael
- Mather John
- McElwain Michael
- McKenzie Kenny
- McLean Brian
- McMaster Matthew
- Melbourne Katie
- Meléndez Marcio
- Menzel Michael
- Merz Kaiya
- Meyett Michele
- Meza Luis
- Milam Stefanie
- Miskey Cherie
- Misselt Karl
- Moller Christopher
- Morrison Jane
- Morse Ernie
- Moseley Harvey
- Mosier Gary
- Mountain Matt
- Mueckay Julio
- Mueller Michael
- Mullally Susan
- Murphy Jess
- Murray Claire
- Murray Katherine
- Mustelier David
- Muzerolle James
- Mycroft Matthew
- Myers Richard
- Myrick Kaila
- Nanavati Shashvat
- Nance Elizabeth
- Nayak Omnarayani
- Naylor Bret
- Neff Susan
- Neira Irma Quispe
- Nelan Edmund
- Nickson Bryony
- Nielson Alethea
- Nieto-Santisteban Maria
- Nikolov Nikolay
- Noriega-Crespo Alberto
- O'Shaughnessy Brian
- O'Sullivan Brian
- Ochs William
- Ogle Patrick
- Oleszczuk Brenda
- Olmsted Joseph
- Ortega Alvaro Labiano
- Osborne Shannon
- Ottens Richard
- Owens Beverly
- Pacifici Camilla
- Pagan Alyssa
- Page James
- Park Sang
- Parrish Keith
- Patapis Polychronis
- Paul Lee
- Pauly Tyler
- Pavlovsky Cheryl
- Pedder Andrew
- Peek Matthew
- Pena-Guerrero Maria
- Pennanen Konstantin
- Perez Yesenia
- Perna Michele
- Perriello Beth
- Perrin Marshall
- Phillips Kevin
- Pietraszkiewicz Martin
- Pinaud Jean-Paul
- Pirzkal Norbert
- Pitman Joseph
- Piwowar Aidan
- Platais Vera
- Plate Maurice Te
- Player Danielle
- Plesha Rachel
- Pollizi Joe
- Polster Ethan
- Pontoppidan Klaus
- Porterfield Blair
- Proffitt Charles
- Pueyo Laurent
- Pulliam Christine
- Quirt Brian
- Ramsay Leah
- Rapp Greg
- Rapp Robert
- Rauscher Bernard
- Ravindranath Swara
- Rawle Timothy
- Regan Michael
- Reichard Timothy A.
- Reis Carl
- Ressler Michael E.
- Rest Armin
- Reynolds Paul
- Rhue Timothy
- Richon Karen
- Rickman Emily
- Ridgaway Michael
- Rieke George
- Rieke Marcia
- Rigby Jane
- Ritchie Christine
- Rix Hans-Walter
- Robberto Massimo
- Robinson Gregory
- Robinson Michael
- Robinson Orion
- Rock Frank
- Rodriguez David
- Roellig Thomas
- Rohrbach Scott
- Roman Anthony
- Romelfanger Fred
- Rose Perry
- Roteliuk Anthony
- Roth Marc
- Rothwell Braden
- Rowlands Neil
- Roy Arpita
- Royer Pierre
- Royle Patricia
- Rui Chunlei
- Rumler Peter
- Runnels Joel
- Russ Melissa
- Rustamkulov Zafar
- Ryden Grant
- Ryer Holly
- Sabata Modhumita
- Sabatke Derek
- Sabbi Elena
- Samuelson Bridget
- Sapp Benjamin
- Sappington Bradley
- Sargent B.
- Sauer Arne
- Scheithauer Silvia
- Schlawin Everett
- Schlitz Joseph
- Schmitz Tyler
- Schneider Analyn
- Schreiber Jürgen
- Schulze Vonessa
- Schwab Ryan
- Scott John
- Sembach Kenneth
- Shanahan Clare
- Shaughnessy Bryan
- Shaw Richard
- Shawger Nanci
- Shay Christopher
- Sheehan Evan
- Shen Sharon
- Sherman Allan
- Shiao Bernard
- Shih Hsin-Yi
- Shivaei Irene
- Sienkiewicz Matthew
- Sing David
- Sirianni Marco
- Sivaramakrishnan Anand
- Skipper Joy
- Sloan Gregory
- Slocum Christine
- Slowinski Steven
- Smith Corbett
- Smith Denise
- Smith Eric
- Smith Erin
- Snyder Gregory
- Soh Warren
- Sohn Tony
- Soto Christian
- Spencer Richard
- Stallcup Scott
- Stansberry John
- Stark Christopher
- Starr Carl
- Starr Elysia
- Stewart Alphonso
- Stiavelli Massimo
- Straughn Amber
- Strickland David
- Stys Jeff
- Summers Francis
- Sun Fengwu
- Sunnquist Ben
- Swade Daryl
- Swam Michael
- Swaters Robert
- Swoish Robby
- Taylor Joanna M.
- Taylor Rolanda
- Tea Mason
- Teague Kelly
- Telfer Randal
- Temim Tea
- Thatte Deepashri
- Thompson Christopher
- Thompson Linda
- Thomson Shaun
- Tikkanen Tuomo
- Tippet William
- Todd Connor
- Toolan Sharon
- Tran Hien
- Trejo Edwin
- Truong Justin
- Tsukamoto Chris
- Tustain Samuel
- Tyra Harrison
- Ubeda Leonardo
- Underwood Kelli
- Uzzo Michael
- Valenti Jeff
- Van Campen Julie
- Vandal Thomas
- Vandenbussche Bart
- Vila Begoña
- Volk Kevin
- Wahlgren Glenn
- Waldman Mark
- Walker Chanda
- Wander Michel
- Warfield Christine
- Warner Gerald
- Wasiak Matthew
- Watkins Mitchell
- Weaver Andrew
- Weilert Mark
- Weiser Nick
- Weiss Ben
- Weissman Sarah
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- Wheate Lauren
- Wheatley Elizabeth
- Wheeler Thomas
- White Rick
- Whiteaker Kevin
- Whitehouse Paul
- Whiteleather Jennifer
- Whitman William
- Williams Christina
- Willmer Christopher
- Willott Chris
- Willoughby Scott
- Wilson Andrew
- Wirth Gregory
- Wislowski Emily
- Wolf Erin
- Wolfe David
- Wolff Schuyler
- Workman Bill
- Wright Gillian
- Wright Ray
- Wu Carl
- Wu Rai
- Wymer Kristen
- Yates Kayla
- Yeager Christopher
- Yeates Jared
- Yerger Ethan
- Yoon Jinmi
- Young Alice
- Yu Susan
- Zak Dean
- Zeidler Peter
- Zhou Julia
- Zielinski Thomas
- Zincke Cristian
- Zonak Stephanie
- Publication venue
- 'IOP Publishing'
- Publication date
- 10/04/2023
- Field of study
This paper characterizes the actual science performance of the James Webb
Space Telescope (JWST), as determined from the six month commissioning period.
We summarize the performance of the spacecraft, telescope, science instruments,
and ground system, with an emphasis on differences from pre-launch
expectations. Commissioning has made clear that JWST is fully capable of
achieving the discoveries for which it was built. Moreover, almost across the
board, the science performance of JWST is better than expected; in most cases,
JWST will go deeper faster than expected. The telescope and instrument suite
have demonstrated the sensitivity, stability, image quality, and spectral range
that are necessary to transform our understanding of the cosmos through
observations spanning from near-earth asteroids to the most distant galaxies.Comment: 5th version as accepted to PASP; 31 pages, 18 figures;
https://iopscience.iop.org/article/10.1088/1538-3873/acb29
Synthesis of the Elements in Stars
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- A. Bohr
- A. D. Thackeray
- A. E. S. Green
- A. G. W. Cameron
- A. G. W. Cameron
- A. H. Wapstra
- A. Hemmendinger
- A. Hemmendinger
- A. J. Deutsch
- A. McKellar
- A. McKellar
- A. McKellar
- A. McKellar
- A. R. Sandage
- Alder
- Aller
- Arp
- Baade
- Booth
- Bosman-Crespin
- Bromley
- Burbidge
- Burbidge
- C. B. Haselgrove
- C. C. Patterson
- C. D. Coryell
- C. F. von Weizsäcker
- C. F. von Weizsäcker
- C. F. von Weizsäcker
- C. Hayashi
- C. L. Bailey
- C. L. Cowan
- C. O. Muehlhause
- C. P. Swann
- C. P. Swann
- Cook
- Cowan
- D. B. Duncan
- D. E. Osterbrock
- D. J. Hughes
- D. M. Popper
- E. C. Halbert
- E. E. Salpeter
- E. E. Salpeter
- E. E. Salpeter
- E. E. Salpeter
- E. E. Salpeter
- E. E. Salpeter
- E. E. Salpeter
- E. J. Stanley
- E. J. Woodbury
- E. J. Öpik
- E. J. Öpik
- E. M. Burbidge
- E. M. Burbidge
- E. M. Burbidge
- E. M. Burbidge
- E. Margaret Burbidge
- F. Ajzenberg
- F. B. Wood
- F. Beskow
- F. Hoyle
- F. Hoyle
- F. Hoyle
- F. Hoyle
- F. Hoyle
- F. Hoyle
- F. Reines
- Feshbach
- Fields
- Fowler
- Fowler
- Fowler
- G. A. Gurzadian
- G. Gamow
- G. Gamow
- G. H. Herbig
- G. J. Wasserburg
- G. M. Griffiths
- G. Münch
- G. R. Burbidge
- G. R. Burbidge
- G. R. Burbidge
- G. R. Burbidge
- G. R. Burbidge
- G. Traving
- G. Traving
- Good
- H. A. Bethe
- H. Bondi
- H. Brown
- H. C. Urey
- H. C. van de Hulst
- H. E. Suess
- H. Hurwitz
- H. L. Johnson
- H. L. Johnson
- H. N. Russell
- H. W. Babcock
- Hagedorn
- Halbert
- Hayakawa
- Henyey
- Hoyle
- Humason
- J. A. Wheeler
- J. B. Marion
- J. Crawford
- J. H. Fregeau
- J. H. Fregeau
- J. H. Noon
- J. L. Greenstein
- J. L. Greenstein
- J. L. Greenstein
- J. L. Greenstein
- J. L. Greenstein
- J. L. Greenstein
- J. L. Greenstein
- J. L. Greenstein
- J. M. Blatt
- J. R. Huizenga
- J. R. Huizenga
- J. R. Huizenga
- J. R. Huizenga
- J. R. Oppenheimer
- J. S. Smart
- J. S. Smart
- J. W. Chamberlain
- J. Weneser
- K. Gottstein
- K. Hunger
- K. Würm
- Kaplon
- L. Berman
- L. H. Aller
- L. H. Aller
- L. H. Aller
- L. H. Aller
- L. H. Aller
- L. H. Aller
- L. Heller
- L. Spitzer
- L. Spitzer
- Lagar
- M. Awschalom
- M. G. Mayer
- M. Schmidt
- M. Schwarzschild
- N. Bohr
- N. G. Roman
- N. G. Roman
- N. Tanner
- N. U. Mayall
- Nakagawa
- Noon
- O. J. Eggen
- O. J. Eggen
- O. J. Eggen
- O. Klein
- O. Kofoed-Hansen
- O. Struve
- O. Struve
- O. Struve
- P. C. Keenan
- P. C. Keenan
- P. C. Keenan
- P. C. Keenan
- P. Fong
- P. P. Parenago
- P. Swings
- P. W. Merrill
- P. W. Merrill
- P. W. Merrill
- P. W. Merrill
- Patterson
- Patterson
- R. A. Alpher
- R. A. Alpher
- R. Bouigue
- R. Davis
- R. F. Sanford
- R. F. Sanford
- R. G. Teske
- R. G. Thomas
- R. H. Curtiss
- R. Hofstadter
- R. J. Northcott
- R. L. Adgie
- R. Minkowski
- R. N. Hall
- Reynolds
- S. G. Nilsson
- Schwarzschild
- Schwarzschild
- T'o-t'o Sung-Shih
- T. D. Kinman
- T. D. Lee
- T. Snyder
- Tollestrup
- Turkevitch
- V. F. Weisskopf
- V. M. Goldschmidt
- W. A. Fowler
- W. A. Fowler
- W. A. S. Lamb
- W. Baade
- W. Baade
- W. Buscombe
- W. Buscombe
- W. E. Siri
- W. H. Johnson
- W. P. Bidelman
- W. P. Bidelman
- W. P. Bidelman
- W. P. Bidelman
- W. P. Bidelman
- W. P. Bidelman
- W. P. Bidelman
- Way
- William A. Fowler
- Woodbury
- Wu
- Y. Fujita
- Y. Fujita
- Y. Fujita
- Y. Fujita
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- Field of study
Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Abercrombie Daniel
- Abu Zeid Shimaa
- Ackert Andrew
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Jordon Rowe
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Agapitos Antonis
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahmed Ijaz
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Al-bataineh Ayman
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexakhin Vadim
- Alexander James
- Alimena Juliette
- Allen Brandon
- Almond John
- Alunni Solestizi Luisa
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Anderson Ian
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Anelli Christopher
- Antonelli Louis
- Antropov Iurii
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Askew Andrew
- Attikis Alexandros
- Aubin Alexandre
- Auffray Etiennette
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Aşılar Ece
- Baarmand Marc M
- Baber Mark
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Ball Austin
- Ball Fionn
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbieri Richard
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Baron Owen
- Barone Luciano
- Barria Patrizia
- Barrio Luna Mar
- Bartek Rachel
- Barth Christian
- Bartosik Nazar
- Bartók Márton
- Baskakov Alexey
- Battilana Carlo
- Baty Austin
- Bauerdick Lothar AT
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beck Lana
- Beernaert Kelly
- Behera Prafulla Kumar
- Behnamian Hadi
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Beirão Da Cruz E Silva Cristóvão
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benelli Gabriele
- Beni Noemi
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Beri Suman Bala
- Bernardes Cesar Augusto
- Bernardini Jacopo
- Bernet Colin
- Berry Douglas
- Berry Edmund
- Berryhill Jeffrey
- Bertl Willi
- Besancon Marc
- Betchart Burton
- Betts Russell Richard
- Bhandari Rohan
- Bhardwaj Ashutosh
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhawandeep Bhawandeep
- Bhopatkar Vallary
- Bhowmik Sandeep
- Bi Ran
- Bialkowska Helena
- Bian Jian-Guo
- Bianchini Lorenzo
- Bianco Stefano
- Bierwagen Katharina
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
- Bilki Burak
- Bilmis Selcuk
- Bin Anuar Afiq Aizuddin
- Bisello Dario
- Bitioukov Sergei
- Blekman Freya
- Blinov Vladimir
- Blobel Volker
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Boccali Tommaso
- Bocci Andrea
- Bodek Arie
- Boimska Bożena
- Boletti Alessio
- Bolla Gino
- Bonacorsi Daniele
- Bonato Alessio
- Bondu Olivier
- Boos Edouard
- Boren Samuel
- Bornheim Adolf
- Borras Kerstin
- Bortignon Pierluigi
- Borzou Ahmad
- Bose Tulika
- Botta Cristina
- Boudoul Gaelle
- Bouhali Othmane
- Bourilkov Dimitri
- Bouvier Elvire
- Bowen James
- Bradmiller-Feld John
- Braghieri Alessandro
- Braibant-Giacomelli Sylvie
- Brandstetter Johannes
- Brandt Stephanie
- Branson James G
- Breedon Richard
- Breto Guillermo
- Brew Christopher
- Brianza Luca
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brinson Jessica
- Brito Lucas
- Brochero Cifuentes Javier Andres
- Brochet Sébastien
- Brodski Michael
- Brom Jean-Marie
- Brondolin Erica
- Brooke James John
- Brown Robert M
- Brun Hugues
- Bruner Christopher
- Bruno Giacomo
- Buchmuller Oliver
- Bucinskaite Inga
- Bundock Aaron
- Bunkowski Karol
- Bunn Julian
- Buontempo Salvatore
- Burkett Kevin
- Burns Douglas
- Burns Dustin
- Burt Kira
- Burton Darren
- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H
- Buttignol Michael
- Butz Erik
- Bylinkin Alexander
- Bylsma Ben
- Byszuk Adrian
- Bäni Lukas
- Cabrera Andrés
- Cabrillo Iban Jose
- Cadamuro Luca
- Caillol Cécile
- Cakir Altan
- Calabria Cesare
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
- Cali Ivan Amos
- Call Kenneth
- Calligaris Luigi
- Calpas Betty
- Calvelli Valerio
- Calvert Brian
- Calvo Enrique
- Caminada Lea
- Campagnari Claudio
- Campanini Renato
- Campbell Alan
- Camporesi Tiziano
- Candelise Vieri
- Canelli Maria Florencia
- Cankocak Kerem
- Capiluppi Paolo
- Caputo Claudio
- Carlin Roberto
- Carnes Andrew
- Carpinteyro Severiano
- Carrera Jarrin Edgar
- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Cartiglia Nicolo
- Carvalho Antunes De Oliveira Alexandra
- Carvalho Wagner
- Carver Matthew
- Casal Bruno
- Casarsa Massimo
- Casasso Stefano
- Castaldi Rino
- Castello Roberto
- Castilla-Valdez Heriberto
- Castiñeiras De Saa Juan Ramon
- Castle James
- Castro Andrea
- Caudron Adrien
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Celik Ali
- Centis Vignali Matteo
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Chabert Eric Christian
- Chadeeva Marina
- Chamizo Llatas Maria
- Chang Paoti
- Chang You-Hao
- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Chapon Emilien
- Charaf Otman
- Charlot Claude
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chauhan Shubhanshu
- Chauhan Sushil
- Chaves Jorge
- Chawla Ridhi
- Chen Geng
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Mingshui
- Chen Po-Hsun
- Chen Ye
- Chen Yi
- Chen Zhenyu
- Chenarani Shirin
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chierici Roberto
- Chinellato Jose
- Chiorboli Massimiliano
- Chistov Ruslan
- Chlebana Frank
- Cho Sungwoong
- Choi Minkyoo
- Choi Suyong
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C
- Choudhury Somnath
- Chtchipounov Leonid
- Chu Jennifer
- Chudasama Ruchi
- Chwalek Thorsten
- Ciangottini Diego
- Cieri Davide
- Cihangir Selcuk
- Cimmino Anna
- Ciocci Maria Agnese
- Cipriani Marco
- Cirkovic Predrag
- Citron Matthew
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R
- Clare Robert
- Clarida Warren
- Clarke Christopher
- Clement Emyr
- Clerbaux Barbara
- Cockerill David JA
- Cocoros Alice
- Codispoti Giuseppe
- Colafranceschi Stefano
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Colombo Fabio
- Connor Patrick
- Contardo Didier
- Conte Eric
- Contreras-Campana Christian
- Contreras-Campana Emmanuel
- Conway John
- Conway Rylan
- Cooper Seth
- Cooperstein Stephane
- Cornelis Tom
- Corpe Louie
- Cossutti Fabio
- Costa Marco
- Costa Salvatore
- Costanza Francesco
- Coubez Xavier
- Couderc Fabrice
- Coughlan John A
- Courbon Benoit
- Cousins Robert
- Covarelli Roberto
- Cowden Christopher
- Cox Bradley
- Cox Peter Timothy
- Creanza Donato
- Cremonesi Matteo
- Cristella Leonardo
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Curras Esteban
- Curry David
- Cussans David
- Custódio Analu
- Cutts David
- Czellar Sandor
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- D'imperio Giulia
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dalchenko Mykhailo
- Dall'Osso Martino
- Dallavalle Gaetano-Marco
- Damarseckin Serdal
- Damgov Jordan
- Danilov Mikhail
- Daponte Vincenzo
- Das Souvik
- Daskalakis Georgios
- Dasu Sridhara
- Dauncey Paul
- David Tinoco Mendes Andre
- Davies Gavin
- Davignon Olivier
- de Barbaro Pawel
- De Boer Wim
- De Bruyn Isabelle
- De Castro Manzano Pablo
- De Cosa Annapaola
- De Filippis Nicola
- De Gruttola Michele
- De Guio Federico
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Nardo Guglielmo
- De Oliveira Martins Carley
- De Palma Mauro
- De Remigis Paolo
- De Roeck Albert
- de Trocóniz Jorge F
- De Visscher Simon
- De Wit Adinda
- De Wolf Eddi A
- Degano Alessandro
- Deiters Konrad
- Dejardin Marc
- Del Re Daniele
- Delaere Christophe
- Delannoy Andrés G
- Delannoy Hugo
- Delcourt Martin
- Delgado Peris Antonio
- Delgado Andrea
- Dell'Orso Roberto
- Della Negra Michel
- Della Ricca Giuseppe
- Demaria Natale
- Demina Regina
- Demiragli Zeynep
- Demiroglu Zuhal Seyma
- Denegri Daniel
- Depasse Pierre
- Derdzinski Mark
- Dermenev Alexander
- Deroover Kevin
- Dev Nabarun
- Devetak Damir
- Dewanjee Ram Krishna
- Dey Sourav
- Di Francesco Agostino
- Di Guida Salvatore
- Di Marco Emanuele
- Di Maria Riccardo
- Di Matteo Leonardo
- Di Mattia Alessandro
- Diamond Brendan
- Diemoz Marcella
- Dierlamm Alexander
- Dietz Charles
- Dietz-Laursonn Erik
- Diez Pardos Carmen
- Dildick Sven
- Dilsiz Kamuran
- Dimitrov Anton
- Dinardo Mauro Emanuele
- Dini Paolo
- Dishaw Adam
- Dissertori Günther
- Dittmann Jay
- Dittmar Michael
- Dittmer Susan
- Doan Thi Hien
- Dobson Marc
- Dobur Didar
- Dodd Laura
- Dogra Sunil
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- Northup Michael
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- Yazgan Efe
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- Yetkin Taylan
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- Yilmaz Yetkin
- Yohay Rachel
- Yonamine Ryo
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- Yoo Jaehyeok
- You Can
- Yu Geum Bong
- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabel James
- Zabi Alexandre
- Zaganidis Nicolas
- Zagoździńska Agnieszka
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenoni Florian
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhao Jingzhou
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zientek Margaret
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Sunan Kalijaga State Islamic University
- Publication date
- 01/01/2012
- Field of study
Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis
MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV
- Author
- Aarrestad Thea Klaeboe
- Aarup Petersen Henriette
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abercrombie Daniel
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Eric
- Adams Mark Raymond
- Adams Todd
- Adloff Catherine
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmed Asar
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Akpinar Alp
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Allen Brandon
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amram Oz
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yu.
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Aruta Caterina
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Asghar Muhammad Irfan
- Asilar Ece
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Atanasov Ivan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awan Muhammad Imran Malik
- Ayala Edy
- Aydogmus Sen Fatma
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden A.
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Baldenegro Barrera Cristian
- Ball Austin
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
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- Baringer Philip
- Barnes Virgil E
- Barney David
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- Bein Samuel
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- Bell Ken W
- Bellan Riccardo
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- BRANDAO MALBOUISSON Helena
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- Wiedenbeck Sebastian
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- Winterbottom Daniel
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- Wong Wing Yan
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- Wright Douglas
- Wu Zhenbin
- Wuchterl Sebastian
- Wulz Claudia-Elisabeth
- Wuyckens Sophie
- Wyslouch Bolek
- Würthwein Frank
- Xia Fan
- Xiao Jie
- Xiao Meng
- Xiao Rui
- Xie Si
- Xie Wei
- Yagil Avraham
- Yalvac Metin
- Yan Furong
- Yang Unki
- Yang Yu Chul
- Yao Yao
- YARAR Hevjin
- Yates Brent
- Yazgan Efe
- Yetkin Elif Asli
- Yi Kai
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- Yoon Inseok
- You Zhengyun
- Yu David
- Yu Geum Bong
- Yu Intae
- Yu Shin-Shan
- Yuan Li
- Yuan Siqi
- Yuldashev Bekhzod S
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabi Alexandre
- Zacharopoulou Anna
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zenaiev Oleksandr
- Zeuner Wolfram Dietrich
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Zhicai
- Zhao Jingzhou
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Ziemons Tim
- Zientek Margaret
- Zlebcik Radek
- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Zygala Lara
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe
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