Ultra-estrutura e morfometria das células do endotélio corneano de jibóias (Boa constrictor) obtidas pela microscopia eletrônica de varredura

17

A 46,XX testicular disorder of sex development caused by a Wilms’ tumour Factorâ 1 (WT1) pathogenic variant

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146930/1/cge13459_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146930/2/cge13459.pd

Escala do comportamento do treinador: versão treinador (ECT-T) e versão atleta (ECT-A): o que o treinador diz é confirmado pelos seus atletas?

Objetivou-se verificar o nível de associação entre as percepções de atletas e treinadores de esportes coletivos e individuais nas seis dimensões do comportamento do treinador - Treinamento Físico (TF), Treinamento Técnico (TT), Preparação Mental (PM), Estabelecimento de Objetivos (EO), Reforço Pessoal Positivo (RPP), Reforço Pessoal Negativo (RPN) - acessado pela Escala do Comportamento do Treinador - Versão Treinador (ECT-T) e Versão Atleta (ECT-A). Participaram 181 atletas (114 homens e 67 mulheres) de nove modalidades esportivas com idade média de 17,15 anos (± 1,48) e seus respectivos treinadores (N = 32), todos do sexo masculino, com idade média de 32,88 (± 8,91). Treinadores e atletas responderam aos 38 itens de mesmo conteúdo dos questionários mencionados. A correlação não-paramétrica de Spearman mostrou a inexistência de associação significativa, ao nível a = 0,05, entre as percepções treinadores e atletas de modalidades coletivas nas dimensões TT, PM, EO e RPP. Entre treinadores e atletas de modalidades individuais também não foram verificadas associações significativas em cinco dimensões: TF, TT, PM, EO e RPP. Dentre outras razões, a baixa compatibilidade entre as percepções de atletas treinadores, pode estar relacionada a falhas no processo de organização do treinamento. Além disso, o relacionamento de cada treinador com os atletas sob o seu comando parece informar mais do que a simples categorização: modalidades coletivas versus individuaisThe purpose of this study was to verify the level of association between athletes and their coaches' perceptions, according to the kind of sport (individual or group), in the six dimensions of coaching behavior - Physical Training (PT); Technical Training (TT); Mental Preparation (MP); Goal Setting (GS); Personal Positive Rapport (PPR) Personal Negative Rapport (PNR) - accessed by the two Brazilian versions of Coaching Behavior Scale for Sport: Coaches (ECT-T) and Athletes Versions (ECT-A). Participated 181 athletes (114 male and 67 female) of nine different sports with mean age of 17.15 years (± 1.48) and their respective coaches (N = 32), all male, with mean age of 32.88 years (± 8.91). Coaches and athletes answered the 38 items, which have the same content, in the mentioned questionnaires. The non-parametric Spearman correlation showed the inexistence of significant association, at a level = 0.05, between the coaches and athletes perception of group sports in the dimensions TT, MP, GS and PPR. In addition, there were no significant correlations between coaches and athletes perceptions of individual sports in the following dimensions: PT, TT, MP, GS and PPR. Among others reasons, the low compatibility involving the coaches and athletes perceptions can be associated with failures in the training organization process. Besides, the relationship of each coach with their athletes appears to add more information than the simple categorization: group modalities versus individual modalitie

EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome.

OBJECTIVES: Develop recommendations for women's health issues and family planning in systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS). METHODS: Systematic review of evidence followed by modified Delphi method to compile questions, elicit expert opinions and reach consensus. RESULTS: Family planning should be discussed as early as possible after diagnosis. Most women can have successful pregnancies and measures can be taken to reduce the risks of adverse maternal or fetal outcomes. Risk stratification includes disease activity, autoantibody profile, previous vascular and pregnancy morbidity, hypertension and the use of drugs (emphasis on benefits from hydroxychloroquine and antiplatelets/anticoagulants). Hormonal contraception and menopause replacement therapy can be used in patients with stable/inactive disease and low risk of thrombosis. Fertility preservation with gonadotropin-releasing hormone analogues should be considered prior to the use of alkylating agents. Assisted reproduction techniques can be safely used in patients with stable/inactive disease; patients with positive antiphospholipid antibodies/APS should receive anticoagulation and/or low-dose aspirin. Assessment of disease activity, renal function and serological markers is important for diagnosing disease flares and monitoring for obstetrical adverse outcomes. Fetal monitoring includes Doppler ultrasonography and fetal biometry, particularly in the third trimester, to screen for placental insufficiency and small for gestational age fetuses. Screening for gynaecological malignancies is similar to the general population, with increased vigilance for cervical premalignant lesions if exposed to immunosuppressive drugs. Human papillomavirus immunisation can be used in women with stable/inactive disease. CONCLUSIONS: Recommendations for women's health issues in SLE and/or APS were developed using an evidence-based approach followed by expert consensus

Clinical and epidemiological characteristics of patients from Ribeirão Preto, SP, Brazil, with AIDS and oportunistic infections

Com o objetivo de conhecer e atualizar as características clínicas e epidemiológicas dos pacientes com aids e infecções oportunistas na região de Ribeirão Preto, foram revisados os prontuários médicos de 1019 pacientes com aids, do sub - grupo IVc (CDC), atendidos no HCFMRP, no período de janeiro de 1992 a agosto de 1996.Os seguintes itens foram analisados: data do primeiro atendimento, sexo, idade, cidade em que residia, via provável de aquisição do HIV, época do primeiro exame anti -HIV positivo, número de linfócitos CD4/mm3 por ocasião do primeiro atendimento, data da primeira manifestação infecciosa após o início do seguimento, tipo e número de complicação(ões) infecciosa(s), data do óbito e tipo de infecção(ões) diagnosticada(s) nos pacientes que faleceram. Os resultados, quando comparados com os obtidos no período de 1987 a 1991, apontam para modificações importantes em algumas características dos pacientes no segundo período, como aumento da via de transmissão heterossexual do HIV, aumento da participação de mulheres na casuística, uma tendência de diagnóstico mais precoce da infecção pelo HIV e aumento da sobrevida dos pacientes. Por outro lado, os pacientes continuam sendo acometidos por ampla gama de processos infecciosos durante a evolução da aids, com destaque para a candidíase, as pneumonias bacterianas, a neurotoxoplasmose, a pneumonia por P.carinii, a sinusite, a diarréia e a neurocriptococose. Menção especial deve ser feita à tuberculose que acometeu cerca de 30% dos pacientes durante o período de seguimento.    In order to up-to-date informations about the clinical and epidemiological characteristics of AIDS patients with opportunistic infections, from the Ribeirão Preto region, we revised 1019 medical records of individuals belonging to IVc AIDS sub-group attended in HCFMRP in the period from January 1992 to August 1996. The following parameters were analyzed: date of the first medical examination, sex, age, city of residence, probable form of acquisition of HIV, time of the first anti-HIV positive test, number of CD4+/mm3 lymphocytes at the beginning of the follow-up, date of the first infectious episodes after the beginning of the follow-up, type and number of infectious episodes, date of the death and the type of infectious processes diagnosed in the patients that died. The results point out for important modifications in some characteristics of the patients over the last five years. We noted, by comparing with the results obtained in the period of 1987 to 1991, an increase in the heterosexual transmission of HIV and an increase of the number of women with AIDS; a tendency of an early diagnosis of the HIV infection and an increase in patients’ survival. In the other hand patients continued presenting a wide range of infectious processes during the AIDS evolution with emphasis for candidiasis, for bacterial pneumonia, for neuro-toxoplasmosis, for pneumocystosis, for sinusitis, for diarrhoea, and for neuro-cryptococcosis. Special mention must be done for tuberculosis, which was diagnosed in 30% of the patients during the follow-up period

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC

Measurements of inclusive jet suppression in heavy ion collisions at the LHC provide direct sensitivity to the physics of jet quenching. In a sample of lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the anti-kt algorithm with values for the distance parameter that determines the nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp. Jet production is found to be suppressed by approximately a factor of two in the 10% most central collisions relative to peripheral collisions. Rcp varies smoothly with centrality as characterized by the number of participating nucleons. The observed suppression is only weakly dependent on jet radius and transverse momentum. These results provide the first direct measurement of inclusive jet suppression in heavy ion collisions and complement previous measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables, submitted to Physics Letters B. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02