Letter from NY Law Faculty in Support of Diploma Privilege

For more information, please refer to Karen Sloan\u27s article, Hundreds of New York Law Professors Endorse Emergency Diploma Privilege, published by the New York Law Journal and appearing on Law.com on July 22, 2020. Additional Signatories: Susan Abraham (New York Law School), Michelle Adams (Benjamin N. Cardozo School of Law), Miriam Albert (Maurice A. Deane School of Law at Hofstra University), Jose E. Alvarez (New York University School of Law), Claudia Angelos (New York University Law School), Deborah Archer (New York University Law School), Jennifer Arlen (New York University Law School), Anna Arons (New York University Law School), Jonathan Askin (Brooklyn Law School), Barbara L. Atwell (Elisabeth Haub School of Law at Pace University), Aditi Bagchi (Fordham University School of Law), Rachel Barkow (New York University Law School), Melynda Barnhart (New York Law School), John Q. Barrett (St. John’s University School of Law), Christine P. Bartholomew (University at Buffalo School of Law), Mark Bartholomew (University at Buffalo School of Law), Jennifer Baum (St. John’s University School of Law), Christopher Beauchamp (Brooklyn Law School), Debra Bechtel (Brooklyn Law School), Edith Beerdsen (New York University School of Law), Peter A. Bell (Syracuse University College of Law), Lenni Benson (New York Law School), Paula Berg (City University of New York School of Law), Anya Bernstein (University at Buffalo School of Law), Beryl Blaustone (City University of New York School of Law) Susan Block-Lieb Cooper (Fordham University School of Law), Pamela Bookman (Fordham University School of Law), Rebecca M. Bratspies (City University of New York School of Law), Ray Brescia (Albany Law School), Richard Briffault (Columbia Law School), William Brooks (Touro College Jacob D. Fuchsberg Law Center), Emily Brown (Syracuse University College of Law), James J. Brudney (Fordham University School of Law), Christopher Buccafusco (Benjamin N. Cardozo School of Law), Jessica Bulman-Pozen Betts (Columbia Law School), Keith Bybee (Syracuse University College of Law), Gina M. Calabrese (St. John’s University School of Law), Janet M. Calvo (City University of New York School of Law), Ann Cammett (City University of New York School of Law) Juli Campagna (Maurice A. Deane School of Law at Hofstra University), Bennett Capers (Fordham University School of Law), Stacy Caplow (Brooklyn Law School), Rosa Castello (St. John’s University School of Law), Oscar G. Chase (New York University School of Law), Asima Chaudhary (City University of New York School of Law), Nina Chernoff (City University of New York School of Law), Elaine Chiu (St. John’s University School of Law), Wilfred U. Codrington III (Brooklyn Law School), Jim Cohen (Fordham University School of Law), Jeffrey M. Colon (Fordham University School of Law), Jordana Confino (Fordham University School of Law), George W. Conk (Fordham University School of Law), Elizabeth B. Cooper (Fordham University School of Law), Briane Cornish (Brooklyn Law School), Bridget J. Crawford (Elisabeth Haub School of Law at Pace University), Laura E. Cunningham (Benjamin N. Cardozo School of Law), Noel B. Cunningham (New York University School of Law), Jason J. Czarnezki (Elisabeth Haub School of Law at Pace University), Matthew D\u27Amore (Cornell Law School), Alina Das (New York University School of Law), Lisa Davis (City University of New York School of Law), Christian C. Day (Syracuse University College of Law), Brett M. Dignam (Columbia Law School), Rebekah Diller (Benjamin N. Cardozo School of Law), Shane Dizon (Brooklyn Law School), Laura Dooley (Touro College Jacob D. Fuchsberg Law Center), Ryan Dooley (City University of New York School of Law), David Dorfman (Elisabeth Haub Law School at Pace University), Doron Dorfman (Syracuse University College of Law), Helen Agnes Drew (University at Buffalo School of Law), Catharine Du Bois (Brooklyn Law School), Catherine Baylin Duryea (St John\u27s University School of Law), Robin Effron (Brooklyn Law School), Elizabeth F. Emens (Columbia Law School), Richard A. Epstein (New York University School of Law), Howard Erichson (Fordham University School of Law), Jeffrey Fagan (Columbia Law School), Golnaz Fakhimi (City University of New York School of Law), John D. Feerick (Fordham University School of Law), Dave Fields (City University of New York School of Law), Martin Flaherty (Fordham University School of Law), Katherine Franke (Columbia Law School), Eric M. Freedman (Maurice A. Deane School of Law at Hofstra University), Barry Friedman (New York University School of Law), Jeanne Fromer (New York University School of Law), Kellen Funk (Columbia Law School), Raquel Gabriel (City University of New York School of Law), Paolo Galizzi (Fordham University School of Law), James A. Gardner (University at Buffalo School of Law), David Garland (New York University School of Law), Mark A. Geistfeld (New York University School of Law), Philip M. Genty (Columbia Law School), Doni Gewirtzman (New York Law School), Shubha Ghosh (Syracuse University College of Law), Maeve Glass (Columbia Law School), Cynthia Godsoe (Brooklyn Law School), Rachel T. Goldberg (Cornell Law School), Elizabeth Goldman (Benjamin N. Cardozo School of Law), Julie Goldscheid (City University of New York School of Law), Ann Goldweber (St. John\u27s University School of Law), Natalie Gomez-Velez (City University of New York School of Law), Jennifer Gordon (Fordham University School of Law), Lauryn Gouldin (Syracuse University College of Law), Elayne E. Greenberg (St. John’s University School of Law), Michelle Greenberg-Kobrin (Benjamin N. Cardozo School of Law), Abner Greene (Fordham University School of Law), Jamal Greene (Columbia Law School), Lissa Griffin (Elisabeth Haub School of Law at Pace University), Jill Gross (Elisabeth Haub School of Law at Pace University), Lisa Grumet (New York Law School), Martin Guggenheim (New York University School of Law), Jennifer A. Gundlach (Maurice A. Deane School of Law at Hofstra University), Hugh C. Hansen (Fordham University School of Law), Bernard E. Harcourt (Columbia Law School), Jonathan Harris (New York University School of Law), Melina Healey (Touro College Jacob D. Fuchsberg Law Center), Julia Hernandez (City University of New York School of Law), Tanya Hernandez (Fordham University School of Law), Helen Hershkoff (New York University School of Law), Randy Hertz (New York University School of Law), Robert A. Heverly (Albany Law School), Michael F. Higgins (University at Buffalo School of Law), Tracy Higgins (Fordham University School of Law), Alexis Hoag (Columbia Law School), Martha R. Hochberger (New York Law School), Babe Howell (City University of New York School of Law), Rob Howse (New York University School of Law), Bert I. Huang (Columbia Law School), Carmen Huertas (City University of New York School of Law), Kyron Huigens (Benjamin N. Cardozo School of Law), Tarek Z. Ismail (City University of New York School of Law), Conrad Johnson (Columbia Law School), Paula C. Johnson (Syracuse University College of Law), Kathryn Judge (Columbia Law School), Mitchell Kane (New York University School of Law), Arlene S. Kanter (Syracuse University College of Law), Ramzi Kassem (City University of New York School of Law), Constantine N. Katsoris (Fordham University School of Law), Avery Katz (Columbia Law School), Eileen Kaufman (Touro College Jacob D. Fuchsberg Law Center), Florence Kerner (City University of New York School of Law), Jocelyn Getgen Kestenbaum (Benjamin N. Cardozo School of Law), Richard Klein (Touro College Jacob D. Fuchsberg Law Center), Kate Klonick (St. John’s University School of Law), Lewis Kornhauser (New York University School of Law), Minna Kotkin (Brooklyn Law School), Anita S. Krishnakumar (St. John’s University School of Law), Rebecca M. Kysar (Fordham University School of Law), Sarah Lamdan (City University of New York School of Law), Christine Lazaro (St. John’s University School of Law), Donna Lee (City University of New York School of Law), Nicole Lefton (Maurice A. Deane School of Law at Hofstra University), Arthur S. Leonard (New York Law School), Michael Lewyn (Touro College Jacob D. Fuchsberg Law Center), Theo Liebmann (Maurice A. Deane School of Law at Hofstra University), Edward Lloyd (Columbia Law School), Stephen Loffredo (City University of New York School of Law), Grace M. Lozito (Fordham University School of Law), Shirley Lung (City University of New York School of Law), Mary Lynch (Albany Law School), James Macleod (Brooklyn Law School), Kevin Maillard (Syracuse), Matthew Main (City University of New York School of Law), Deborah C. Malamud (New York University School of Law), Michael W. Martin (Fordham University School of Law), Princess Masilungan (City University of New York School of Law), Camille Massey (City University of New York School of Law), Nancy Maurer (Albany Law School), Andrea McArdle (City University of New York School of Law), Justin McCrary (Columbia Law School), Thomas M. McDonnell (Elisabeth Haub School of Law at Pace University), Kevin McElroy (Maurice A. Deane School of Law at Hofstra University), Peggy McGuinness (St. John’s University School of Law), Estelle M. McKee (Cornell Law School), Mary Helen McNeal (Syracuse University College of Law), Suzette M. Melendez (Syracuse University College of Law), Gillian Metzger (Columbia Law School), Chi Adanna Mgbako (Fordham University School of Law), Flora Midwood (Brooklyn Law School), Kathryn Miller (Benjamin N. Cardozo School of Law), Meredith R. Miller (Touro College Jacob D. Fuchsberg Law Center), Joshua Mitts (Columbia Law School), Kate Mogulescu (Brooklyn Law School), Laura Mott (City University of New York School of Law), Elora Mukherjee (Columbia Law School), Erin Murphy (New York University School of Law), Jessica R. Murray (Syracuse University College of Law), Justin Murray (New York Law School), Melissa Murray (New York University School of Law), Michael B. Mushlin (Elisabeth Haub School of Law at Pace University), Athena D. Mutua (University at Buffalo School of Law), Smita Narula (Elisabeth Haub School of Law at Pace University), Lindsay Nash (Benjamin N. Cardozo School of Law), Robert Nassau (Syracuse University College of Law), Burt Neuborne (New York University School of Law), Elizabeth Nevins (Maurice A. Deane School of Law at Hofstra University), Leslie Newman (Benjamin N. Cardozo School of Law), Jacqueline Nolan-Haley (Fordham University School of Law), Tracy L. Norton (Touro College Jacob D. Fuchsberg Law Center), Anthony O\u27Rourke (University at Buffalo School of Law), Jonathan Oberman (Benjamin N. Cardozo School of Law), Ngozi Okidegbe (Benjamin N. Cardozo School of Law), Judith Olin (University at Buffalo School of Law), Nancy K. Ota (Albany Law School), Jason Parkin (City University of New York School of Law), G. Michael Parsons (New York University School of Law), Frank A. Pasquale (Brooklyn Law School), Russell G. Pearce (Fordham University School of Law), Deborah Pearlstein (Benjamin N. Cardozo School of Law), Talia Peleg (City University of New York School of Law), Katharina Pistor (Columbia Law School), Margot Pollans (Elisabeth Haub School of Law at Pace University), Karen Porter (Brooklyn Law School), David Pozen (Columbia Law School), Edward A. Purcell, Jr. (New York Law School), Paul Radvany (Fordham University School of Law), Aziz Rana (Cornell Law School), Martha Rayner (Fordham University School of Law), LaVonda Reed (Syracuse University College of Law), David J. Reiss (Brooklyn Law School), Alice Ristroph (Brooklyn Law School), Allie Robbins (City University of New York School of Law), Nicholas A. Robinson (Eisabeth Haub School of Law at Pace University), Ruthann Robson (City University of New York School of Law), Sarah Rogerson (Albany Law School), Joseph A. Rosenberg (City University of New York School of Law), Merrick Rossein (City University of New York School of Law), Leif Rubinstein (Touro College Jacob D. Fuchsberg Law Center), David Rudenstine (Benjamin N. Cardozo School of Law), Laura Sager (New York University School of Law), Rosemary Salomone (St. John’s University School of Law), Leslie Salzman (Benjamin N. Cardozo School of Law), Faraz Sanei (New York University School of Law), Carol Sanger (Columbia Law School), Margaret L. Satterthwaite (New York University School of Law), John Henry Schlegel (University at Buffalo School of Law), Elizabeth Schneider (Brooklyn Law School), Jeanne Schroeder (Benjamin N. Cardozo School of Law), Jason Schultz (New York University School of Law), Beth G. Schwartz (Fordham University School of Law), Elizabeth Scott (Columbia Law School), Helen S. Scott (New York University School of Law), Robert E Scott (Columbia Law School), Anthony Sebok (Benjamin N. Cardozo School of Law), Courtney Selby (St. John’s University School of Law), Rena Seplowitz (Touro College Jacob D. Fuchsberg Law Center), John Sexton (New York University School of Law), Houman Shadab (New York Law School), Colleen Shanahan (Columbia Law School), Jeremy Sheff (St. John’s University School of Law), Theodore Silver (Touro College Jacob D. Fuchsberg Law Center), Jocelyn Simonson (Brooklyn Law School), Janet Sinder (Brooklyn Law School), Charisa Smith (City University of New York School of Law), Rachel H. Smith (St. John’s University School of Law), Jeff Sovern (St. John’s University School of Law), Jane M. Spinak (Columbia Law School), Christopher Sprigman (New York University School of Law), Edward Stein (Benjamin N. Cardozo School of Law), John Paul Steines Jr. (New York University School of Law), Jed Stiglitz (Cornell Law School), Katherine Strandburg (New York University School of Law), Susan Sturm (Columbia Law School), Daniel E Subotnik (Touro College Jacob D. Fuchsberg Law Center), Deborah Sundquist O’Malley (Syracuse University College of Law), Olivier Sylvain (Fordham University School of Law), Mary Szto (Syracuse University College of Law), Mateo Taussig-Rubbo (University at Buffalo School of Law), Nelson Tebbe (Cornell Law School), Ruti Teitel (New York Law School), Leslie Y. Garfield Tenzer (Elisabeth Haub School of Law at Pace University), Maria Termini (Brooklyn Law School), Steven Thel (Fordham University School of Law), Kendall Thomas (Columbia University), Monica Todd (Syracuse University), Erin Tomlinson (City University of New York School of Law), Cora True-Frost (Syracuse University College of Law), Jacob Victor (Albany Law School), Rachel Vorspan (Fordham University School of Law), Amy Wallace (New York Law School), Matthew Wansley (Benjamin N. Cardozo School of Law), Ettie Ward (St. John’s University School of Law), G. Ray Warner (St. John’s University School of Law), Daniel Warshawsky (New York Law School), Ian Weinstein (Fordham University School of Law), Samuel N. Weinstein (Benjamin N. Cardozo School of Law), Richard H. Weisberg (Benjamin N. Cardozo School of Law), Robert Wertheimer (Cornell Law School), John Whitlow (City University of New York School of Law), Andrew Williams (New York University School of Law), Rev. Dr. Yvette Wilson-Barnes (City University of New York School of Law), Charles M. Yablon (Benjamin N. Cardozo School of Law), Ellen Yaroshefsky (Maurice A. Deane School of Law at Hofstra University), Steven Zeidman (City University of New York School of Law), Benjamin C. Zipursky (Fordham University School of Law

COOL-LAMPS. IV. A Sample of Bright Strongly Lensed Galaxies at 3 < z < 4

We report the discovery of five bright, strong gravitationally lensed galaxies at 3 < z < 4: COOL J0101+2055 (z = 3.459), COOL J0104−0757 (z = 3.480), COOL J0145+1018 (z = 3.310), COOL J0516−2208 (z = 3.549), and COOL J1356+0339 (z = 3.753). These galaxies have magnitudes of rAB, zAB < 21.81 mag and are lensed by galaxy clusters at 0.26 < z < 1. This sample nearly doubles the number of known bright lensed galaxies with extended arcs at 3 < z < 4. We characterize the lensed galaxies using ground-based grz/giy imaging and optical spectroscopy. We report model-based magnitudes and derive stellar masses, dust content, and star formation rates via stellar population synthesis modeling. Building lens models based on ground-based imaging, we estimate source magnifications ranging from ∼29 to ∼180. Combining these analyses, we derive demagnified stellar masses in the range ${\mathrm{log}}_{10}({M}_{* }/{M}_{\odot })\sim 9.69-10.75$ and star formation rates in the youngest age bin in the range ${\mathrm{log}}_{10}(\mathrm{SFR}/({M}_{\odot }\,{\mathrm{yr}}^{-1}))\sim 0.39-1.46$, placing the sample galaxies on the massive end of the star-forming main sequence in this redshift interval. In addition, three of the five galaxies have strong Lyα emissions, offering unique opportunities to study Lyα emitters at high redshift in future work

Adolescent/Youth Reproductive Mobile Access and Delivery Initiative for Love and Life Outcomes (ARMADILLO) Study: formative protocol for mHealth platform development and piloting

BACKGROUND: There is a high unmet need for sexual and reproductive health (SRH) information and services among youth (ages 15-24) worldwide (MacQuarrie KLD. Unmet Need for Family Planning among Young Women: Levels and Trends 2014). With the proliferation of mobile technology, and its popularity with this age group, mobile phones offer a novel and accessible platform for a discreet, on-demand service providing SRH information. The Adolescent/Youth Reproductive Mobile Access and Delivery Initiative for Love and Life Outcomes (ARMADILLO) formative study will inform the development of an intervention, which will use the popular channel of SMS (text messages) to deliver SRH information on-demand to youth. METHODS/DESIGN: Following the development of potential SMS message content in partnership with SRH technical experts and youth, formative research activities will take place over two phases. Phase 1 will use focus group discussions (FGDs) with youth and parents/caregivers to develop and test the appropriateness and acceptability of the SMS messages. Phase 2 will consist of ‘peer piloting’, where youth participants will complete an SRH outcome-focused pretest, be introduced to the system and then have three weeks to interact with the system and share it with friends. Participants will then return to complete the SRH post-test and participate in an in-depth interview about their own and their peers’ opinions and experiences using ARMADILLO. DISCUSSION: The ARMADILLO formative stage will culminate in the finalization of country-specific ARMADILLO messaging. Reach and impact of ARMADILLO will be measured at later stages. We anticipate that the complete ARMADILLO platform will be scalable, with the potential for national-level adoption

Performance of the CMS Cathode Strip Chambers with Cosmic Rays

The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47 microns to 243 microns. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns

Mitotic Spindle Proteomics in Chinese Hamster Ovary Cells

Mitosis is a fundamental process in the development of all organisms. The mitotic spindle guides the cell through mitosis as it mediates the segregation of chromosomes, the orientation of the cleavage furrow, and the progression of cell division. Birth defects and tissue-specific cancers often result from abnormalities in mitotic events. Here, we report a proteomic study of the mitotic spindle from Chinese Hamster Ovary (CHO) cells. Four different isolations of metaphase spindles were subjected to Multi-dimensional Protein Identification Technology (MudPIT) analysis and tandem mass spectrometry. We identified 1155 proteins and used Gene Ontology (GO) analysis to categorize proteins into cellular component groups. We then compared our data to the previously published CHO midbody proteome and identified proteins that are unique to the CHO spindle. Our data represent the first mitotic spindle proteome in CHO cells, which augments the list of mitotic spindle components from mammalian cells

Standards in semen examination:publishing reproducible and reliable data based on high-quality methodology

Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concordant documents have been published: the 6th edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen, and the International Standard ISO 23162:2021. With these tools, we propose that authors should be instructed to follow these laboratory methods in order to publish studies in peer-reviewed journals, preferable by using a checklist as suggested in an Appendix to this article.Peer reviewe

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

Background: Genome-wide association studies (GWAS) have identified 18 loci associated with serous ovarian cancer (SOC) susceptibility but the biological mechanisms driving these findings remain poorly characterised. Germline cancer risk loci may be enriched for target genes of transcription factors (TFs) critical to somatic tumorigenesis. Methods: All 615 TF-target sets from the Molecular Signatures Database were evaluated using gene set enrichment analysis (GSEA) and three GWAS for SOC risk: discovery (2196 cases/4396 controls), replication (7035 cases/21 693 controls; independent from discovery), and combined (9627 cases/30 845 controls; including additional individuals). Results: The PAX8-target gene set was ranked 1/615 in the discovery (PGSEA&lt;0.001; FDR=0.21), 7/615 in the replication (PGSEA=0.004; FDR=0.37), and 1/615 in the combined (PGSEA&lt;0.001; FDR=0.21) studies. Adding other genes reported to interact with PAX8 in the literature to the PAX8-target set and applying an alternative to GSEA, interval enrichment, further confirmed this association (P=0.006). Fifteen of the 157 genes from this expanded PAX8 pathway were near eight loci associated with SOC risk at P&lt;10−5 (including six with P&lt;5 × 10−8). The pathway was also associated with differential gene expression after shRNA-mediated silencing of PAX8 in HeyA8 (PGSEA=0.025) and IGROV1 (PGSEA=0.004) SOC cells and several PAX8 targets near SOC risk loci demonstrated in vitro transcriptomic perturbation. Conclusions: Putative PAX8 target genes are enriched for common SOC risk variants. This finding from our agnostic evaluation is of particular interest given that PAX8 is well-established as a specific marker for the cell of origin of SOC

A pair of Sub-Neptunes transiting the bright K-dwarf TOI-1064 characterised with CHEOPS

Funding: TGW, ACC, and KH acknowledge support from STFC consolidated grant numbers ST/R000824/1 and ST/V000861/1, and UKSA grant ST/R003203/1.We report the discovery and characterization of a pair of sub-Neptunes transiting the bright K-dwarf TOI-1064 (TIC 79748331), initially detected in the Transiting Exoplanet Survey Satellite (TESS) photometry. To characterize the system, we performed and retrieved the CHaracterising ExOPlanets Satellite (CHEOPS), TESS, and ground-based photometry, the High Accuracy Radial velocity Planet Searcher (HARPS) high-resolution spectroscopy, and Gemini speckle imaging. We characterize the host star and determine Teff,⋆=4734±67K⁠, R⋆=0.726±0.007R⊙⁠, and M⋆=0.748±0.032M⊙⁠. We present a novel detrending method based on point spread function shape-change modelling and demonstrate its suitability to correct flux variations in CHEOPS data. We confirm the planetary nature of both bodies and find that TOI-1064 b has an orbital period of Pb = 6.44387 ± 0.00003 d, a radius of Rb = 2.59 ± 0.04 R⊕, and a mass of Mb=13.5+1.7−1.8 M⊕, whilst TOI-1064 c has an orbital period of Pc=12.22657+0.00005−0.00004 d, a radius of Rc = 2.65 ± 0.04 R⊕, and a 3σ upper mass limit of 8.5 M⊕. From the high-precision photometry we obtain radius uncertainties of ∼1.6 per cent, allowing us to conduct internal structure and atmospheric escape modelling. TOI-1064 b is one of the densest, well-characterized sub-Neptunes, with a tenuous atmosphere that can be explained by the loss of a primordial envelope following migration through the protoplanetary disc. It is likely that TOI-1064 c has an extended atmosphere due to the tentative low density, however further radial velocities are needed to confirm this scenario and the similar radii, different masses nature of this system. The high-precision data and modelling of TOI-1064 b are important for planets in this region of mass–radius space, and it allow us to identify a trend in bulk density–stellar metallicity for massive sub-Neptunes that may hint at the formation of this population of planets.Publisher PDFPeer reviewe

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3′-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk

Aligning the CMS Muon Chambers with the Muon Alignment System during an Extended Cosmic Ray Run

Peer reviewe