67 research outputs found
INCEFA-PLUS Findings on Environmental Fatigue
- Author
- Arrieta Sergio
- Austin Tim
- Bruchhausen Matthias
- Chitty Walter-John
- Cicero Román
- Cicero Sergio
- Cuvilliez Sam
- De Baglion Laurent
- Dundulis Gintautas
- Gourdin Cédric
- Huotilainen Caitlin
- INCEFA-PLUS Consortium
- Le Roux Jean-Christophe
- Mann Jonathan
- Mayinger Wolfgang
- McLennan Alec
- Miroslava Ernestova
- Mottershead Kevin
- Métais Thomas
- Novotny Radek
- Perosanz López Francisco Javier
- Platts Norman
- Procopio Isabela
- Prompt Nicolas
- Spätig Philippe
- Twite Marius
- Vankeerberghen Marc
- Publication venue
- INCEFA-PLUS Consortium
- Publication date
- 01/01/2020
- Field of study
INCEFA-PLUS is a five year project supported by the European Commission HORIZON2020 programme. The project concluded in October 2020. 16 organisations from across Europe have combined forces to deliver new experimental data which is being used to develop improved guidelines for assessment of environmental fatigue damage to ensure safe operation of nuclear power plants. Within INCEFA-PLUS, the effects of mean strain and stress, hold time, strain amplitude and surface finish on fatigue endurance of austenitic stainless steels in light water reactor environments have been studied experimentally.
This document constitutes a Reference Book compiling the research developed within the INCEFA-PLUS Project. It provides a comprehensive overview of the tasks performed, and it also presents the background and the assumptions taken to develop the INCEFA-PLUS experimental and analytical works. It compiles and orders documents and contributions from INCEFA-PLUS partners.This project has received funding from the Euratom research and training program 2014-2018 under grant agreement No 662320
AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine
- Author
- Abadjian Marie-Caline
- Allouch Awatef
- Aloy Marie-Thérèse
- Anderson Carolyn
- Angelovski Goran
- Ardail Dominique
- Balosso Jacques
- Barberi-Heyob Muriel
- Barbier Emmanuel
- Berbeco Ross
- Bort Guillaume
- Boschetti Frédéric
- Bouziotis Penelope
- Butterworth Karl
- Canet-Soulas Emmanuelle
- Chargari Cyrus
- Crémillieux Yannick
- Denat Franck
- Detappe Alexandre
- Deutsch Eric
- Doan Bich-Thuy
- Doussineau Tristan
- Dufort Sandrine
- Evans Michael
- Fries Peter
- Frochot Céline
- Janier Marc
- Lacombe Sandrine
- Larrat Benoit
- Le Duc Géraldine
- Lux François
- Martini Matteo
- McMahon Stephen
- Meriaux Sébastien
- Mignet Nathalie
- Müller Andreas
- Perfettini Jean-Luc
- Porcel Erika
- Prise Kevin
- Rodriguez-Lafrasse Claire
- Rossetti Fabien
- Roux Stéphane
- Sidi-Boumedine Jacqueline
- Thomas Eloïse
- Tillement Olivier
- Tran Vu Long
- Truillet Charles
- Verry Camille
- Publication venue
- 'British Institute of Radiology'
- Publication date
- 01/01/2019
- Field of study
International audienceAGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium chelates. This nanoparticle has been recently accepted in clinical trials in association with radiotherapy. This review will summarize the principal preclinical results that have led to first in man administration. No evidence of toxicity has been observed during regulatory toxicity tests on two animal species (rodents and monkeys). Biodistributions on different animal models have shown passive uptake in tumours due to enhanced permeability and retention effect combined with renal elimination of the nanoparticles after intravenous administration. High radiosensitizing effect has been observed with different types of irradiations in vitro and in vivo on a large number of cancer types (brain, lung, melanoma, head and neck…). The review concludes with the second generation of AGuIX nanoparticles and the first preliminary results on human
DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France
- Author
- Abir Wahab
- Adil Maarouf
- Adrien Delourme
- Agnes Fromont
- Agostino Nozzolillo
- Alain Cr??ange
- Alain Cr??ange
- Alberto Gajofatto
- Alessandra Bellacosa
- Alessandra Protti
- Alessandro d'Ambrosio
- Alessandro Marti
- Alessia d'Arma
- Alessia Di Sapio
- Alessia Sartori
- Alessio Signori
- Alexis Montcuquet
- Alfredo Petrone
- Alvino Bisecco
- Amandine Bordet
- Anastasia Alteno
- Angelica Guareschi
- Aniello Iovino
- Anna Dutto
- Anna Ghazaryan
- Anna M Pietroboni
- Anna Palmieri
- Anna Repice
- Anne Kerbrat
- Anne???Laure Dubessy
- Anne???Marie Guennoc
- Antoine Gueguen
- Antonella Conte
- Antonio Bosco
- Antonio Gallo
- Antonio Ianniello
- Antonio Zito
- Ari??le Azoulay???Cayla
- Arianna Sartori
- Arnaud Gagnol
- Arnaud Kwiatkowski
- Aude Maurousset
- Audrey Rico
- Aur??lie Ruet
- Aurelian Ungureanu
- Aurore Jourdain
- Ayman Tourbah
- Beatrice Biolzi
- Beatrice Maria Allegri Rossi
- Benedetta Bodini
- Bertrand Audoin
- Bertrand Bourre
- Bruno Brochet
- Bruno Giometto
- Bruno Stankoff
- Bruno Stankoff
- C??line Louapre
- Camille Rizzato
- Carla Tortorella
- Carlo Antozzi
- Carlo Piantadosi
- Carlo Pozzilli
- Carolina Gabri Nicoletti
- Caroline Bensa
- Caroline Bensa???Koscher
- Caroline Papeix
- Caroline Pot
- Catalina Coclitu
- Caterina Barril??
- Caterina Lapucci
- Caterina Sgarito
- Catherine Lubetzki
- Cecile Dulau???Metras
- Celine Louapre
- Chiara Bosa
- Chiara Rosa Mancinelli
- Christian Cordano
- Christine Clerc
- Christine Lebrun???Frenay
- Cinzia Cordioli
- Cinzia Cordioli
- Cinzia Scandellari
- Cl??mence Boutiere
- Claire Giannesini
- Clara Chisari
- Clara Guaschino
- Clarisse Carra???Dalliere
- Claudio Correale
- Claudio Gasperini
- Claudio Solaro
- Cristina Fioretti
- Daiana Bezzini
- Dalia Dimitri
- Damiano Baroncini
- Damiano Marastoni
- Damiano Paolicelli
- Damien Biotti
- Dan Buch
- Daniele Imperiale
- David Laplaud
- Davide Maimone
- Diana Ferraro
- Dominique Audry
- Domizia Vecchio
- Donata Guidetti
- Doriana Landi
- Dorothee Videt
- Edouard Januel
- Eduardo Nobile???Orazio
- Eleonora Cocco
- Eleonora Rigoni
- Eleonora Virgilio
- Elisabeth Maillart
- Elisabetta Bucciantini
- Elisabetta Pedrazzoli
- Elisabetta Signoriello
- Elvira Sbragia
- Emanuela Laura Susani
- Emanuele D'Amico
- Emilio Portaccio
- Emmanuelle Page
- Eric Berger
- Eric Manchon
- Eric Thouvenot
- Eric Thouvenot
- Erica Curti
- Erica Grange
- Eva Milano
- Evelyne Planque
- Fabiana Marinelli
- Fay??al Derouiche
- Federco Masserano Zoli
- Federica Pinardi
- Federico Camilli
- Federico Montini
- Filippo Martinelli Boneschi
- Flora Govone
- Flora Lejeune
- Fr??d??ric Taithe
- Fran??oise Durand???Dubief
- Francesca Bovis
- Francesca Calabria
- Francesca Caleri
- Francesca Gobbin
- Francesca Matta
- Francesca Rinaldi
- Francesca Ruscica
- Francesca Sireci
- Francesca Vitetta
- Francesco Corea
- Francesco Crescenzo
- Francesco Patti
- Francesco Patti
- Francesco Teatini
- Franco Granella
- Francois Sellal
- Frederique Le Breton
- G??raldine Androdias???Condemine
- Gabriele Siciliano
- Gabriella Turano
- Gaia Cola
- Giacomo Lus
- Giampaolo Brichetto
- Giancarlo Comi
- Giancarlo Comi
- Gianmarco Abbadessa
- Gianmarco Bellucci
- Gilles Defer
- Gilles Edan
- Gioacchino Tedeschi
- Gioacchino Tedeschi
- Giorgia Teresa Maniscalco
- Giovanna Borriello
- Giovanna De Luca
- Giovanna Konrad
- Giovanna Vaula
- Giovanni Castelnovo
- Girolama Alessandra Marfia
- Giuditta Ilaria Scarano
- Giulia Mallucci
- Giulietta Tabiadon
- Giuseppe Liberatore
- Giuseppe Meucci
- Giuseppe Salemi
- Giuseppina Miele
- Grazia Sibilia
- Guido Ahle
- Guillaume Mathey
- Helene Zephir
- Helene Zephir
- Herv?? Fayolle
- Ignazio Roberto Zarbo
- Ilaria Pesci
- Ionescu Iuliana
- Irene Schiavetti
- Irene Schiavetti
- J??r??me De S??ze
- J??r??mie Papassin
- Jean Capron
- Jean Christophe Corvol
- Jean Christophe Seghezzi
- Jean Pelletier
- Jean Pelletier
- Jean???Christophe Ouallet
- Jean???Philippe Neau
- Jennifer Aboab
- Jerome De Seze
- Jerome Grimaud
- Jessica Frau
- Jonathan Ciron
- Jonathan Ciron
- Julie Boucher
- Julie Pique
- Julien Poupart
- Karine Mougine
- Kevin Bigaut
- Kumaran Deiva
- Laura Brambilla
- Laura Mendozzi
- Laure Michel
- Laurent Guilloton
- Laurent Kremer
- Leonardo Lopiano
- Leonardo Sinisi
- Lia Allegorico
- Livia Pasquali
- Loredana Sabattini
- Lorena Lorefice
- Lorenzo Saraceno
- Luana Evangelista
- Luca Carmisciano
- Luca Carmisciano
- Luca Mancinelli
- Luca Prosperini
- Lucia Appendino
- Lucia Moiola
- Lucia Moiola
- Lucile Gleyze
- Luigi Iasevoli
- Luigi Lavorgna
- Luigi Zuliani
- Luisa Maria Caniatti
- Luisa Past??
- Maddalena Sparaco
- Magalie Rabin
- Marc Coustans
- Marc Debouverie
- Marcello Calogero Romano
- Marcello Moccia
- Marco Bozzali
- Marco Capobianco
- Marco Capobianco
- Marco Della Cava
- Marco Longoni
- Marco Onofrj
- Marco Ronzoni
- Marco Rovaris
- Marco Salvetti
- Marco Salvetti
- Marco Vercellino
- Margherita Monti Bragadin
- Maria Buccafusca
- Maria Cellerino
- Maria Chiara Buscarinu
- Maria Grazia Celani
- Maria Grazia Grasso
- Maria Laura Stromillo
- Maria Malentacchi
- Maria Paola Cabboi
- Maria Petracca
- Maria Pia Amato
- Maria Pia Sormani
- Maria Pia Sormani
- Maria Rita L'Episcopo
- Maria Sessa
- Maria Teresa Ferr??
- Maria Teresa Infante
- Maria Teresa Rilla
- Maria Trojano
- Maria Trojano
- Maria Trotta
- Marianna Lo Re
- Marie Th??audin
- Marie Th??audin
- Marie???celine Fleury
- Marika Vianello
- Marinella Clerico
- Mario A Battaglia
- Mario Alberto Battaglia
- Mario di Napoli
- Mario Fratta
- Marta Ponzano
- Marta Radaelli
- Marta Radaelli
- Marta Zaffira Conti
- Marzia Fronza
- Massimiliano Calabrese
- Massimiliano Mirabella
- Massimo Filippi
- Mathieu Vaillant
- Mathilde Goudot
- Matilde Inglese
- Matteo Lucchini
- Mattia Pozzato
- Maud Pallix???Guyot
- Maura Chiara Danni
- Mauro Zaffaroni
- Mauro Zampolini
- Maya Tchikviladze
- Michella Ibrahim
- Micka??l Zedet
- Mikael Cohen
- Monica Ulivelli
- Nathalie Derache
- Nicola De Rossi
- Nicola De Rossi
- Nicola De Stefano
- Nicolas Collongues
- Nicolas Maubeuge
- Olivier Casez
- Olivier Casez
- Olivier Gout
- Olivier Heinzlef
- Ombline Fagniez
- Paola Cavalla
- Paola Perini
- Paolo Confalonieri
- Paolo De Mitri
- Paolo Gallo
- Paolo Immovilli
- Paolo Immovilli
- Paolo Manganotti
- Paolo Ragonese
- Patrick Hautecoeur
- Patrick Vermersch
- Patrizia Carta
- Patrizia Sola
- Pekes Codjia
- Philippe Kerschen
- Philippe Kerschen
- Pierre Branger
- Pierre Clavelou
- Pierre Clavelou
- Pierre Labauge
- Pierre Labauge
- Pierre Yves Garcia
- Pietro Annovazzi
- Pietro Iaffaldano
- Raffaele Nardone
- Raffaella Cerqua
- Raffaella Clerici
- Rana Assouad
- Raphael De Paz
- Renato Docimo
- Renaud Du Pasquier
- Riccardo Orlandi
- Roberta Lanzillo
- Roberta Motta
- Roberto Balgera
- Roberto Bergamaschi
- Roberto Cantello
- Rocco Capuano
- Rocco Totaro
- Romain Deschamps
- Romain Marignier
- Rosa Iodice
- Rosanna Missione
- Ruggero Capra
- Sabrina Marangoni
- Sabrina Realmuto
- Salimata Gassama
- Salvatore Cottone
- Salvatore Fanara
- Samar S Ayache
- Sandra Vukusic
- Sandra Vukusic
- Sandrine Wiertlewski
- Sara Montepietra
- Sarah Coulette
- Sarah Demorti??re
- Sarah Rasia
- Saskia Bresch
- Sebastiano Arena
- Sebastiano Bucello
- Serena Leva
- Silvia Miante
- Silvia Strumia
- Simona Bonavita
- Simona Malucchi
- Simona Toscano
- Simone Guerrieri
- Simone Tonietti
- Sinead Zeidan
- Sophie Pittion
- St??phane Beltran
- Stefania Federica De Mercanti
- Stefano Biase
- Stefano Sotgiu
- Stefano Vollaro
- Susanna Cordera
- Thibault Moreau
- Thibault Moreau
- Thomas Roux
- Umberto Aguglia
- V??ronique Marcaud
- Valentina Scarano
- Valentina Tomassini
- Valentina Torri Clerici
- Valentino Manzo
- Valeria Barcella
- Valeria Bergamaschi
- Vincenzo Brescia Morra
- Vincenzo Dattola
- Viola Baione
- Vito A. G Ricigliano
- Vittorio Mantero
- Xavier Ayrignac
- Xavier Moisset
- Yanica Mathieu
- Ysoline Beigneux
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2021
- Field of study
We evaluated the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid-19 severity was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti-CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39–3.02, p < 0.001) with Covid-19 severity, whereas interferon indicated a decreased risk (OR = 0.42, 95%CI = 0.18–0.99, p = 0.047). This pooled-analysis confirms an increased risk of severe Covid-19 in patients on anti-CD20 therapies and supports the protective role of interferon
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
- Author
- Abbasi Z
- Abdul-Hamid M Akhlil
- Abel Paul D
- Abrams Paul H
- Adab Fawzi A
- Adamson Andrew
- Adeyoju A
- Adolfson Jan
- Afzal Naveed
- Ahiaku Ernest K N
- Ahmed Munir
- Al Sudani Mohammed L
- Al-Samarraie Amir S M
- Al-Samerraie [Unknown]
- Al-Singary Waleed
- Al-Sudani [Unknown]
- Alcock Christopher
- Alexander Kimberly
- Ali Zulfiqar
- Almond David J
- Alonzi Roberto
- Aly Markus
- Amin Al Olama Ali
- Anderson John
- Andrews Henry
- Andrews Steven
- Anjum Iqbal
- Anson Ken
- Anyamene Nicola A
- Apakama Ike
- Aparcia F
- Archbold J A A
- Arndt Volker
- Ash D
- Ashford Richard F U
- Auvinen Anssi
- Azzabi A
- Badenoch David
- Bahl Amit
- Bailey Karen
- Bailey M J
- Ball Andrew J
- Banerjee G
- Barber Jim
- Barber N
- Baria [Unknown]
- Barnes Douglas G
- Barros-Silva Joao
- Barwell Julian
- Bashir J
- Basu Pradip
- Bates Christopher A
- Batra Jyotsna
- Bax N A
- Baxter-Smith D
- Bdesha Amar
- Beacock Christopher J M
- Beaney Ronald P
- Beard Ralph
- Beatty John D
- Beck Rupert
- Beese Gail
- Beesley Sharon
- Bell C Richard W
- Bellringer James
- Benlloch Garcia Sara
- Benson Richard
- Beresford [Unknown]
- Bevis Christopher R A
- Bhana Rajanee
- Bhanot S
- Bhatnagar A
- Bhatt R I
- Birch Brian
- Birtle Alison
- Bishop M
- Biyani C Shekhar
- Blacklock A R E
- Blades Rosemary
- Bliss Peter
- Bloomfield David J
- Boddy S
- Bollina Prasad
- Bonnington Sue
- Booth C M
- Bose Pradeep
- Bott Michael C
- Bottomley David
- Boucher Nigel R
- Bowen J
- Bower Mark
- Bowsher W G
- Boyd P J R
- Bradshaw Lynne
- Bramble F James
- Brenner Hermann
- Brewster Simon F
- Briggs Tim
- Brock Cathryn
- Brock Sue
- Bromage Stephen
- Broms Michael
- Brough Richard
- Brown Andrew A
- Brown Paul
- Brown Paul M
- Brown Richard
- Brown Stephen
- Browning Tony J
- Bryan N
- Burgess Neil A
- Burns-Cox Nicholas
- Butterbach Katja
- Butterworth Paul C
- Cahill D
- Callaghan P S
- Calleary John
- Calleja M
- Calman Frances
- Camilleri Philip
- Campbell Alister
- Cannon Andrea
- Cannon-Albright Lisa
- Carnell Dawn M
- Carr T W
- Carter Adam C
- Carter Charles J M
- Carter Simon
- Castle Bruce M
- Catto James
- Cavalli-Bjoerkman Carin
- Chadwick David
- Chahal Rohit
- Chakraborti P
- Chappell [Unknown]
- Charig C
- Chetiyawardana Anula D
- Chilton Christopher
- Chinegwundoh F I
- Chong Irene
- Choudhury Ananya
- Chow Wai-Man
- Christmas Timothy J
- Christova Svetlana
- Churn Mark J
- Cieza-Borrella Clara
- Clarke Noel W
- Clavijo-Eisele Jorge
- Clements Judith A
- Coe M
- Coetzee Gerhard A
- Cohen N P
- Coker C
- Cole David J
- Cole O
- Cole Trevor
- Collins Angus
- Collins Gerald
- Collinson Matthew
- Conn I
- Connell C
- Conti David V
- Cook Audrey
- Cook Margaret
- Cooke Peter
- Cooksey Graeme
- Coombs L
- Cooper Debbie
- Copland Robert F
- Cornaby Andrew J
- Cornford P A
- Corolis [Unknown]
- Corr John
- Costello C B
- Coull Mrs N
- Cowan Richard
- Cox Angela
- Cox Robert
- Coyle C
- Crew Jeremy
- Crisp John C
- Cross W
- Cruger Dorthe
- Crundwell Malcolm
- Cummings [Unknown]
- Cybulski Cezary
- Dadaev Tokhir
- Dahar Nazeer
- Daniel Francis N
- Darrad J
- Daruwala Pallon
- Das Gautam
- Datta Shibendra
- Davidson S
- Davies Joseph
- Davis Michael
- Davison Owen W
- Dawkins Guy
- Dawson Chris
- De Bolla Alan R
- Dearnaley David
- Desai Ken M
- Deutsch George P
- Dick John
- Dickinson Andrew J
- Dickson Jeanette
- Dikov Tihomir
- Dinneen Michael
- Dixit Sanjay
- Dobbs H Jane
- Doble A
- Doble Andrew
- Dodds David
- Doherty Alan
- Donaldson P
- Donovan Jenny L
- Dooldeniya M
- Douglas S Fiona
- Down Liz
- Drake [Unknown]
- Duchesne Gill M
- Duffy Peter
- Dunn Michael
- Dunsmuir W D
- Durkan Garrett
- Durrani Sajid K
- Easton Douglas
- Eaton Alan C
- Eccles Diane
- Eckert Allison
- Eddy B
- Eden C D
- Edwards J
- Eeles Rosalind A
- El-Modir A
- Elkabir Jeremy
- Elliott Emma
- Elliott P Tony
- Ellis B W
- Ellis R
- Elves Andrew W S
- Elwell Christine
- Emberton Mark
- Emmerson Louise
- England Roland C D
- Errington R D
- Evans D Gareth
- Falconer Alison
- Fawcett Derek
- Featherston C
- Featherstone Carolyn J
- Feggetter Jeremy
- Ferguson C
- Fermont D
- Ferro Michael
- Fisher Cyril
- Fitzgerald Liesel
- Fitzgerlad Liesel M
- Fletcher Matthew
- Folkes A
- Ford Trevor F
- Foster Paul W
- Franks Kevin N
- Freedman Mathew
- Frim Olivera
- Gale Joanna
- Gallegos Christopher
- Gelister James S
- George Anne
- Ghana [Unknown]
- Gibbs Stephanie
- Gilbert Hugh
- Giles Graham G
- Gillatt David
- Glaholm John
- Glass Jonathan M
- Glenister James
- Goode Thomas D
- Gordon E M
- Govindasami Koveela
- Gower Richard L
- Graham John
- Green Damian
- Greenland Jonathan
- Grieve Robert
- Griffiths Thomas R L
- Gronberg Henrik
- Gujral Sandy
- Gupta Nishi
- Gurun Riza Murat
- Gustafsson Sven
- Guy Michelle
- Guy Peter J
- Haiman Christopher A
- Haldar Neil
- Halder N
- Haley James
- Hamdy F C
- Hamdy Freddie
- Hamilton C
- Hammonds John
- Hampson S J
- Hanbury Damien C
- Hardman P D John
- Harland Stephen J
- Harney John M
- Harper Peter
- Harris D
- Harris Sarah
- Harrison G S M
- Harriss D R
- Harvey-Hills N
- Hawkyard Simon
- Hazel Steve
- Hazelett Dennis J
- Heath Catherine M
- Heathcote Peter
- Hehir Michael
- Hellawell Giles O
- Henderson Brian E
- Hendry David
- Henley Mike
- Henrique Rui
- Henry Ann
- Herbert Pippa
- Herkommer Kathleen
- Hetherington John
- Hickish Tamas
- Hicks James A
- Hilman Serena
- Hindley Richard
- Hindmarsh John R
- Hines John
- Hingorani M
- Ho Edwin T S
- Hodgson Shirley
- Hoffman U
- Holden David
- Holding Peter
- Hollingdale A
- Hollins Graham W
- Holmes Simon A V
- Holt Sarah
- Hopper John L
- Horan Gail
- Horwich Alan
- Hoskin Peter
- Howell Graham P
- Howson Joanne
- Hrouda D
- Huddart Robert
- Hudson Liz
- Hughes Michael
- Hughes Owen
- Hughes Rob
- Humber Caroline
- Iacovou John W
- Ibrahim A
- Inglis John A
- Irving Stuart
- Irwin C
- Iversen Peter
- Izatt Louise
- Izegbu Victor
- Jameel Basharat
- James Michael J
- James N
- James R Lester
- Javle Pradip
- Jenkins P
- Jhavar Sameer
- Johansson Jan-Erik
- Jones Chris R
- Jones David A
- Jones Gareth
- Jones Mandy
- Joseph J
- Joss Shelagh
- Jugurnauth-Little Sara
- Kachakova Darina
- Kaisary Amir
- Kaliski Alexandre L
- Kaneva Radka
- Kapur G
- Karim O
- Karlsson Ami
- Karp Stephen J
- Kedda Mary-Anne
- Keeley F X
- Kelkar Anand R
- Kelleher J P
- Kelly John
- Kenwrick Sue
- Kerr Kris
- Key Tim J
- Khan F
- Khaw Kay-Tee
- Khoo Vincent
- Kibel Adam S
- Kierzek Andrzej
- Kimber Rachel M
- Kinder R
- Kirby Roger S
- Kirk David
- Kirkbride Peter
- Kirollos Magdi M
- Klarskov Peter
- Kluzniak Wojciech
- Kockelbergh Roger
- Koenig Philip C W C
- Kooiman Gordon G
- Koreich O
- Kote-Jarai Zsofia
- Koupparis Anthony
- Kourah Mohamed
- Kraus Sigurd
- Kujala Paula
- Kujawa Magda L
- Kulkarni Ravi
- Kumar M
- Kumar Rajeev
- Kunkler Ian H
- Kynaston H
- Kynaston Howard
- Lachlan Katherine L
- Laing Robert
- Lalloo Fiona
- Lancashire M
- Lane Athene
- Langley Stephen E M
- Laniado Marc
- Larner T R
- Lau Maurice W
- Lawrence W T
- Lawson Anne
- Le Roux Pieter J
- Leader Mary
- Lee A
- Lee J O
- Lee L
- Lemburger R John
- Lennon Teresa
- Leone Priscilla
- Leongamornlert Daniel
- Lester Jason
- Leung Hing
- Lewis D Christopher
- Lewis J
- Li Qiuyan
- Lim Hui-Yi
- Lin Hui-Yi
- Liston Thomas
- Livni Naomi
- Livsey Jacqueline
- Lloyd S
- Locke Imogen
- Lodge Richard
- Logue John
- Longmuir Mark
- Lophatananon Artitaya
- Lophatonanon Artitaya
- Lubinski Jan
- Lucas Malcolm G
- Luedeke Manuel
- Luscombe C J
- Lydon Anna
- Lynch Michael
- Lynn Naing N K
- Lyons Norma
- MacDermott James P A
- Macdonagh Ruaraidh P
- Macdonald [Unknown]
- Madaan Sanjeev
- Madhava Kudingila R
- Maeaettaenen Liisa
- Maguire Joseph
- Maher E R
- Mahmood Rana
- Maia Sofia
- Maier Christiane
- Mair Graeme H M
- Malone Greg
- Malone Peter R
- Mangar Stephen A
- Mantle Mark
- Mark I
- Marsden Gemma
- Mason M D
- Mason Malcolm
- Mason Robert
- Matanhelia [Unknown]
- Matenhelia Shyam
- Matthews Philip N
- McAleese J
- McBride Donna
- Mcdonnell Shannon K
- McDonnell Shannon K
- McFarlane Jonathan
- McGrath [Unknown]
- McIlhenny Craig
- McInerney Paul
- McIntosh Gregor
- McKinna F
- McLaren Duncan
- McLarty Esther
- McMenemin Rhona
- McNeill Alan
- McNicholas T A
- Meddings Robert N
- Mee A David
- Melcher Lucinda
- Memon [Unknown]
- Menzes Pravin
- Michael Agnieszka
- Miller Marek
- Mills Robert
- Mitchell S
- Mitev Vanio
- Mithal Natasha
- Mitkova Atanaska
- Mitra Anita
- Mobb Gillian E
- Moffat Leslie E F
- Mokete [Unknown]
- Money-Kyrle Julian
- Montgomery Bruce
- Moody Hilary
- Moody Martin P
- Morgan Angela
- Morley Roland
- Morris Sean B
- Morrison Patrick
- Mort Diana
- Mostafid Amir H
- Motiwala Hanif
- Mufti Gulzar
- Muir Gordon
- Muir Kenneth
- Mumtaz Faiz
- Murphy Michael
- Murray Alexandra
- Murray Keith W
- Murrell Shirley
- Murtola Teemu
- Muthukumar D
- Naerger Harry
- Namasivayam Siva
- Nargund Vinod
- Nawrocki [Unknown]
- Neal David E
- Neilson Donald
- Nethersell A
- Newby Jacqueline C
- Newman Hugh
- Newton R
- Nielsen Sune F
- Nordestgaard Børge G
- O'Boyle P J
- O'Brien J
- O'Brien Tim S
- O'Donnell H
- O'Donoghue E
- O'Donoghue Neil
- O'Reilly P
- O'Rourke J S
- O'Sullivan Joe
- O'Sullivan Patricia
- Oakley Neil
- Ogden Chris
- Ohja Hemant
- Oliver Tim
- Omara Tracy
- Ong Eng K
- Osborn David
- Ostler Peter
- Owen J
- Palfrey Edward
- Panades Miguel
- Panakis Niki
- Pancharatnam M
- Pandha Hardev
- Pantelides Michalakis L
- Panwar U
- Parikh Omi
- Park Hyun
- Park Jong Y
- Parker Chris
- Parker Christopher H
- Parys Bohdan T
- Pascoe Sarah
- Pashayan Nora
- Patel Anup
- Paterson Joan
- Pathack S
- Pati Jhumur
- Patterson Helen
- Pattu [Unknown]
- Paul A
- Paul Alan
- Paulo Paula
- Payne Heather
- Peake David
- Pedersen John
- Pedley I
- Pengelly A
- Peracha Amjad M
- Perry Matthew
- Persad Raj
- Peters John
- Pharoah Paul
- Philp N H
- Philp T
- Pickering Lisa M
- Pigott Katharine
- Pinto Pedro
- Plail R
- Plowman P Nicholas
- Pocock Richard D
- Pope A J
- Popert Rick
- Popov Elenko
- Porter Tim
- Potter John M
- Pow-Sang Julio
- Powell Christopher
- Powell Philip
- Powles Thomas B
- Prasad Krishna
- Prasad Seshadri Sri
- Prejbisz J W
- Prescott Stephen
- Protheroe Andrew
- Qureshi Khaver N
- Raby Nigel
- Radlein Selina
- Ragavan Narasimhan
- Raju Palaniappa G S
- Ramachandra Prakash B
- Raman R
- Rane Abhay
- Rankin Julia
- Rao Y
- Ratan Hari L
- Ravi Ramachandran
- Ravishankar K
- Read [Unknown]
- Reddy Paul J
- Rimington Peter R
- Rinckleb Antje
- Rincon Maria
- Riska Shaun
- Ritchie Peter A
- Roberts J Trevor
- Robertson Andrew
- Robinson Angus
- Robinson Anne C
- Robinson Lee Q
- Rochester Mark A
- Roder Andreas
- Rogers P B
- Rosario Derek
- Rosenbaum Tomas P
- Rothwell Neil
- Rowbotham Carl
- Rowe [Unknown]
- Rowley Kathryn
- Ruddy Deborah
- Rundle John
- Russell John M
- Ryan P G
- Sabharwal A
- Saggar Anand K
- Samanci Ali
- Sangar Vijay K
- Santos Joana
- Saunders Edward J
- Saunders Pamela
- Sawyer Emma J
- Saxby M F
- Schaid Daniel J
- Schleutker Johanna
- Schumacher Fredrick
- Schwaibold Hartwig
- Scoble John E
- Scrase Christopher
- Selim [Unknown]
- Sellers Thomas
- Sells Henry
- Sethia Krishna K
- Severi Gianluca
- Shackley David C
- Shaffer [Unknown]
- Shah Nihil
- Shakespeare D
- Shanley Sue
- Sharma Neerah K
- Sheehan Denise J
- Sherwin Elizabeth
- Shum Poh Lin
- Side Lucy
- Sidek Norma
- Signorello Lisa B
- Sikora Karol
- Simcock R
- Sinclair Andrew M
- Singh Pravin
- Siva M
- Slavov Chavdar
- Smith James
- Smith Michael F
- Sokal Michael
- Sole Graham M
- Southey Melissa C
- Speakman Mark J
- Spiers Alexander
- Spurdle Amanda
- Sreenivasan Thiagarajan
- Srihari Narayanan N
- Srinivasan [Unknown]
- Sriram Rajagopalan
- Staffurth John N
- Stanford Janet L
- Stattin Paer
- Stegmaier Christa
- Stephens Sarah
- Stewart D
- Stockdale Andrew
- Stott Mark A
- Stower M J
- Strachan John R
- Stuart Nicholas S A
- Sugden Elaine
- Summerton Duncan
- Sundar Santhanam
- Sundaram S K
- Suresh Gokarakonda
- Susnerwala Shabbir
- Swami Kuchibhotla S
- Symons Stephanie J
- Syndikus Isabel
- Taari Kimmo
- Tahir Saad
- Tammela Teuvo L
- Tammela Teuvo L J
- Tanquay J
- Taylor J W
- Taylor John W
- Teixeira Manuel R
- Terry T
- Thibodeau Stephen N
- Thomas Robert J
- Thomas Stephen A
- Thompson Alan
- Thompson Pauline
- Thomson Alastair H
- Thurston A
- Tidball Sarah
- Tillmans Lori
- Tilsley Owen
- Tindall Stuart F
- Tipples K
- Tong [Unknown]
- Toussi Hamid
- Toy Elizabeth W
- Travis Ruth C
- Trembath Richard C
- Tulloch David N
- Turner Kevin J
- Turner Megan
- Tweedle James
- Tymrakiewicz Malgorzata
- Tyrell C J
- Umez-Eronini N
- Urwin Graeme H
- Vale Justin A
- Van As [Unknown]
- Van As Nicholas
- Vasanthan Subramaniam
- Vesey Sean
- Vilarino-Varela Maria
- Violet John
- Virdi Jaspal
- Viñuela Ana
- Vlahova Aleksandrina
- Vogel Walther
- Wade Robert
- Wahlfors Tiina
- Waite Katherine
- Walker E M
- Walker Roger
- Wallace David M A
- Wallinder Hans
- Wang Liang
- Watkin Nicholas A
- Watson M E
- Waxman J H
- Waymont Brian
- Weaver Andrew
- Webb Ralph J
- Wedderburn Andrew
- Weischer Maren
- Wells Paula
- Wemyss-Holden G D
- Weston P M T
- Wheatley Duncan
- Whelan P
- Whillis D
- Whitmore Ian
- Wiklund Fredrik
- Wilde Adam D
- Wiles Vicki
- Wilkins Marie
- Wilkinson Rosemary
- Williams John H
- Williams Simon
- Willis Michael
- Wills Michael I
- Wilson J R
- Wilson Richard
- Winkler Mathias H
- Wise Marcus
- Wokozorczyk Dominika
- Wokołorczyk Dominika
- Wood Glenn
- Woodhams Simon
- Woodhouse C
- Woodward Cathryn
- Woolf [Unknown]
- Woolfenden K A
- Worlding Jane
- Wright Mark
- Wu Huihai
- WYLIE [Unknown]
- Wylie James P
- Wynne Chris
- Yeadon Trina
- Zachariah Babu
- Zang Angelika
- Zarkar A
- Zheng Wei
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2015
- Field of study
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
TRY plant trait database – enhanced coverage and open access
- Author
- Aakala Tuomas
- Abedi Mehdi
- Acosta Alicia T. R.
- Adamidis George C.
- Adamson Kairi
- Aiba Masahiro
- Albert Cécile H.
- Alcántara Julio M.
- Alcázar C Carolina
- Aleixo Izabela
- Ali Hamada
- Amiaud Bernard
- Ammer Christian
- Amoroso Mariano M.
- Anand Madhur
- Anderson Carolyn
- Anten Niels
- Antos Joseph
- Apgaua Deborah Mattos Guimarães
- Ashman Tia‐Lynn
- Asmara Degi Harja
- Asner Gregory P.
- Aspinwall Michael
- Atkin Owen
- Aubin Isabelle
- Baastrup‐Spohr Lars
- Bahalkeh Khadijeh
- Bahn Michael
- Baker Timothy
- Baker William J.
- Bakker Jan P.
- Baldocchi Dennis
- Baltzer Jennifer
- Banerjee Arindam
- Baranger Anne
- Barlow Jos
- Barneche Diego R.
- Baruch Zdravko
- Bastianelli Denis
- Battles John
- Bauerle William
- Bauters Marijn
- Bazzato Erika
- Beckmann Michael
- Beeckman Hans
- Beer Arend Jacobus
- Beest Mariska
- Beierkuhnlein Carl
- Bekker Renee
- Belfry Gavin
- Belluau Michael
- Beloiu Mirela
- Benavides Raquel
- Benomar Lahcen
- Berdugo‐Lattke Mary Lee
- Berenguer Erika
- Bergamin Rodrigo
- Bergmann Carlucci Marcos
- Bergmann Joana
- Berner Logan
- Bernhardt‐Römermann Markus
- Bigler Christof
- Bjorkman Anne D.
- Blackman Chris
- Blanco Carolina
- Blonder Benjamin
- Blumenthal Dana
- Bocanegra‐González Kelly T.
- Bodegom Peter M.
- Boeckx Pascal
- Bohlman Stephanie
- Boisvert‐Marsh Laura
- Bond William
- Bond‐Lamberty Ben
- Boom Arnoud
- Boonman Coline C. F.
- Bordin Kauane
- Boughton Elizabeth H.
- Boukili Vanessa
- Bowman David M. J. S.
- Bravo Sandra
- Brendel Marco Richard
- Breugel Michiel
- Broadley Martin R.
- Brown Kerry A.
- Bruelheide Helge
- Brumnich Federico
- Bruun Hans Henrik
- Bruy David
- Buchanan Serra W.
- Bucher Solveig Franziska
- Buchmann Nina
- Buitenwerf Robert
- Bunker Daniel E.
- Burrascano Sabina
- Burslem David F. R. P.
- Butterfield Bradley J.
- Byun Chaeho
- Böhning‐Gaese Katrin
- Bönisch Gerhard
- Bürger Jana
- Caccianiga Marco
- Cadotte Marc
- Cailleret Maxime
- Camac James
- Camarero Jesús Julio
- Campany Courtney
- Campetella Giandiego
- Campos Juan Antonio
- Cano‐Arboleda Laura
- Canullo Roberto
- Carbognani Michele
- Carvalho Fabio
- Casanoves Fernando
- Castagneyrol Bastien
- Catford Jane A.
- Cavender‐Bares Jeannine
- Cerabolini Bruno E. L.
- Cervellini Marco
- Chacón‐Madrigal Eduardo
- Chapin F. Stuart
- Chapin Kenneth
- Chelli Stefano
- Chen Anping
- Chen Si‐Chong
- Cherubini Paolo
- Chianucci Francesco
- Choat Brendan
- Chung Kyong‐Sook
- Chytrý Milan
- Ciccarelli Daniela
- Coll Lluís
- Collins Courtney G.
- Conti Luisa
- Coomes David
- Cornelissen Johannes H. C.
- Cornwell William K.
- Corona Piermaria
- Coyea Marie
- Craine Joseph
- Craven Dylan
- Cromsigt Joris P. G. M.
- Csecserits Anikó
- Cufar Katarina
- Cuntz Matthias
- Dahlin Kyla M.
- Dainese Matteo
- Dalke Igor
- Dalle Fratte Michele
- Dang‐Le Anh Tuan
- Danihelka Jirí
- Dannoura Masako
- Dawson Samantha
- De Frutos Angel
- De Long Jonathan R.
- Dechant Benjamin
- Delagrange Sylvain
- Delpierre Nicolas
- Derroire Géraldine
- Dias Arildo S.
- Diaz‐Toribio Milton Hugo
- Dimitrakopoulos Panayiotis G.
- Dios Victor Resco
- Dobrowolski Mark
- Doktor Daniel
- Domingues Tomas F.
- Dong Ning
- Dransfield John
- Dressler Stefan
- Duarte Leandro
- Ducouret Emilie
- Dullinger Stefan
- Durka Walter
- Duursma Remko
- Dymova Olga
- Díaz Sandra
- Dřevojan Pavel
- Eckstein Rolf Lutz
- Ejtehadi Hamid
- Elser James
- Emilio Thaise
- Engemann Kristine
- Erfanian Mohammad Bagher
- Erfmeier Alexandra
- Esquivel‐Muelbert Adriane
- Esser Gerd
- Estiarte Marc
- E‐Vojtkó Anna
- Fagan William F.
- Fagúndez Jaime
- Falster Daniel S.
- Fan Ying
- Fang Jingyun
- Farris Emmanuele
- Fazlioglu Fatih
- Feng Yanhao
- Fernandez‐Mendez Fernando
- Ferrara Carlotta
- Ferreira Joice
- Fidelis Alessandra
- Finegan Bryan
- Firn Jennifer
- Flowers Timothy J.
- Flynn Dan F. B.
- Fontana Veronika
- Forey Estelle
- Forgiarini Cristiane
- Frangipani Marcelo
- Frank Dorothea
- François Louis
- Frenette‐Dussault Cedric
- Freschet Grégoire T.
- Fry Ellen L.
- Fyllas Nikolaos M.
- Gachet Sophie
- Gallagher Rachael
- Ganade Gislene
- Ganga Francesca
- García‐Palacios Pablo
- Gargaglione Verónica
- Garnier Eric
- Garrido Jose Luis
- Gasper André Luís
- Gea‐Izquierdo Guillermo
- Gibson David
- Gillison Andrew N.
- Giroldo Aelton
- Glasenhardt Mary‐Claire
- Gleason Sean
- Gliesch Mariana
- Goldberg Emma
- Gonzalez‐Akre Erika
- Gonzalez‐Andujar Jose L.
- González‐Melo Andrés
- González‐Robles Ana
- Graae Bente Jessen
- Granda Elena
- Graves Sarah
- Green Walton A.
- Gregor Thomas
- Gross Nicolas
- Guerin Greg R.
- Gutiérrez Alvaro G.
- Göldel Bastian
- Günther Angela
- Haddock Lillie
- Haines Anna
- Hall Jefferson
- Hambuckers Alain
- Han Wenxuan
- Harrison Sandy P.
- Hattingh Wesley
- Hawes Joseph E.
- He Pengcheng
- He Tianhua
- Heberling Jacob Mason
- Helm Aveliina
- Hempel Stefan
- Hentschel Jörn
- Hereş Ana‐Maria
- Herz Katharina
- Heuertz Myriam
- Hickler Thomas
- Hietz Peter
- Higuchi Pedro
- Hipp Andrew L.
- Hirons Andrew
- Hock Maria
- Hogan James Aaron
- Holl Karen
- Honnay Olivier
- Hornstein Daniel
- Hou Enqing
- Hough‐Snee Nate
- Hovstad Knut Anders
- Hérault Bruno
- Ichie Tomoaki
- Igić Boris
- Illa Estela
- Isaac Marney
- Ishihara Masae
- Ivanov Leonid
- Ivanova Larissa
- Iversen Colleen M.
- Izquierdo Jordi
- Jackson Benjamin
- Jackson Robert B.
- Jactel Hervé
- Jagodzinski Andrzej M.
- Jandt Ute
- Jansen Steven
- Jenkins Thomas
- Jentsch Anke
- Jespersen Jens Rasmus Plantener
- Jiang Guo‐Feng
- Johansen Jesper Liengaard
- Johnson David
- Jokela Eric J.
- Joly Carlos Alfredo
- Jordan Gregory J.
- Joseph Grant Stuart
- Junaedi Decky
- Junker Robert R.
- Justes Eric
- Kabzems Richard
- Kane Jeffrey
- Kaplan Zdenek
- Kattenborn Teja
- Kattge Jens
- Kavelenova Lyudmila
- Kearsley Elizabeth
- Kempel Anne
- Kenzo Tanaka
- Kerkhoff Andrew
- Khalil Mohammed I.
- Kinlock Nicole L.
- Kissling Wilm Daniel
- Kitajima Kaoru
- Kitzberger Thomas
- Kjøller Rasmus
- Klein Tamir
- Kleunen Mark
- Kleyer Michael
- Klimešová Jitka
- Klipel Joice
- Kloeppel Brian
- Klotz Stefan
- Knops Johannes M. H.
- Kohyama Takashi
- Koike Fumito
- Kollmann Johannes
- Komac Benjamin
- Komatsu Kimberly
- Kraft Nathan J. B.
- Kramer Koen
- Kreft Holger
- Kumarathunge Dushan
- Kuppler Jonas
- Kurokawa Hiroko
- Kurosawa Yoko
- Kuyah Shem
- König Christian
- Kühn Ingolf
- Laclau Jean‐Paul
- Lafleur Benoit
- Lallai Erik
- Lamb Eric
- Lamprecht Andrea
- Larkin Daniel J.
- Laughlin Daniel
- Lavorel Sandra
- Le Bagousse‐Pinguet Yoann
- Leadley Paul
- Lee Tali
- Lens Frederic
- Lewis Simon L.
- Lhotsky Barbara
- Li Xine
- Li Yuanzhi
- Lichstein Jeremy W.
- Liebergesell Mario
- Lim Jun Ying
- Lin Yan‐Shih
- Linares Juan Carlos
- Liu Chunjiang
- Liu Daijun
- Liu Udayangani
- Livingstone Stuart
- Llusià Joan
- Lohbeck Madelon
- Lopez‐Gonzalez Gabriela
- Lososová Zdeňka
- Louault Frédérique
- Lukeš Petr
- Lukács Balázs A.
- Luo Yunjian
- Lussu Michele
- López‐García Álvaro
- Ma Siyan
- Maciel Rabelo Pereira Camilla
- Mack Michelle
- Maire Guerric
- Maire Vincent
- Malhado Ana Claudia Mendes
- Mallik Azim
- Manning Peter
- Manzoni Stefano
- Marchetti Zuleica
- Marchino Luca
- Marcilio‐Silva Vinicius
- Marcon Eric
- Marignani Michela
- Markesteijn Lars
- Marques Marcia
- Martin Adam
- Martínez‐Garza Cristina
- Martínez‐Vilalta Jordi
- Mason Kelly
- Mason Norman
- Massad Tara Joy
- Masse Jacynthe
- Mayrose Itay
- Mazzochini Guilherme G.
- Mašková Tereza
- McCarthy James
- McCormack M. Luke
- McCulloh Katherine
- McFadden Ian R.
- McGill Brian J.
- McPartland Mara Y.
- Medeiros Juliana S.
- Medlyn Belinda
- Meerts Pierre
- Mehrabi Zia
- Meir Patrick
- Melo Felipe P. L.
- Mencuccini Maurizio
- Meredieu Céline
- Merwe Stephni
- Messier Julie
- Metsaranta Juha
- Michaletz Sean T.
- Michelaki Chrysanthi
- Migalina Svetlana
- Milla Ruben
- Miller Jesse E. D.
- Minden Vanessa
- Ming Ray
- Mokany Karel
- Moles Angela T.
- Molnár Attila, V
- Molofsky Jane
- Molz Martin
- Montgomery Rebecca A.
- Monty Arnaud
- Moravcová Lenka
- Moreno‐Martínez Alvaro
- Moretti Marco
- Mori Akira S.
- Mori Shigeta
- Morris Dave
- Morrison Jane
- Mucina Ladislav
- Mueller Sandra
- Muir Christopher D.
- Munoz François
- Myers‐Smith Isla H.
- Myster Randall W.
- Mäkelä Annikki
- Mäkinen Harri
- Mészáros Ilona
- Müller Sandra Cristina
- Nagano Masahiro
- Naidu Shawna
- Narayanan Ayyappan
- Natesan Balachandran
- Negoita Luka
- Nelson Andrew S.
- Neuschulz Eike Lena
- Ni Jian
- Niedrist Georg
- Nieto Jhon
- Niinemets Ülo
- Nolan Rachael
- Nottebrock Henning
- Nouvellon Yann
- Novakovskiy Alexander
- Nystuen Kristin Odden
- O\u27Grady Anthony
- O\u27Hara Kevin
- O\u27Reilly‐Nugent Andrew
- Oakley Simon
- Oberhuber Walter
- Ohtsuka Toshiyuki
- Oliveira Ricardo
- Olson Mark E.
- Onipchenko Vladimir
- Onoda Yusuke
- Onstein Renske E.
- Ordonez Jenny C.
- Osada Noriyuki
- Ostonen Ivika
- Ottaviani Gianluigi
- Otto Sarah
- Overbeck Gerhard E.
- Ozinga Wim A.
- Pahl Anna T.
- Paine C. E. Timothy
- Pakeman Robin J.
- Papageorgiou Aristotelis C.
- Parfionova Evgeniya
- Patacca Marco
- Paula Susana
- Paule Juraj
- Pauli Harald
- Pausas Juli G.
- Peco Begoña
- Penuelas Josep
- Perea Antonio
- Peri Pablo Luis
- Petisco‐Souza Ana Carolina
- Petraglia Alessandro
- Petritan Any Mary
- Phillips Oliver L.
- Pierce Simon
- Pillar Valério D.
- Pinho Bruno X.
- Pisek Jan
- Plas Fons
- Pomogaybin Alexandr
- Poorter Hendrik
- Portsmuth Angelika
- Poschlod Peter
- Potvin Catherine
- Pounds Devon
- Powell A. Shafer
- Power Sally A.
- Prentice Iain Colin
- Prinzing Andreas
- Puglielli Giacomo
- Pyšek Petr
- Pärtel Meelis
- Raevel Valerie
- Rammig Anja
- Ransijn Johannes
- Ray Courtenay A.
- Reich Peter B.
- Reichstein Markus
- Reid Douglas E. B.
- Ribeiro Sabina
- Richardson Sarah
- Riibak Kersti
- Rillig Matthias C.
- Riviera Fiamma
- Robert Elisabeth M. R.
- Roberts Scott
- Robroek Bjorn
- Roddy Adam
- Rodrigues Arthur Vinicius
- Rogers Alistair
- Rollinson Emily
- Rolo Victor
- Ronzhina Dina
- Roscher Christiane
- Rosell Julieta A.
- Rosenfield Milena Fermina
- Rossi Christian
- Roux Elizabeth
- Roux Peter C.
- Roy David B.
- Royer‐Tardif Samuel
- Ruiz‐Peinado Ricardo
- Rumpf Sabine B.
- Rusch Graciela M.
- Ryo Masahiro
- Réjou‐Méchain Maxime
- Römermann Christine
- Rüger Nadja
- Sack Lawren
- Saldaña Angela
- Salgado‐Negret Beatriz
- Salguero‐Gomez Roberto
- Sande Masha T.
- Santacruz‐García Ana Carolina
- Santa‐Regina Ignacio
- Santos Joaquim
- Sardans Jordi
- Scalon Marina C.
- Schamp Brandon
- Scherer‐Lorenzen Michael
- Schleuning Matthias
- Schmid Bernhard
- Schmidt Marco
- Schmitt Sylvain
- Schneider Julio V.
- Schowanek Simon D.
- Schrader Julian
- Schrodt Franziska
- Schuldt Bernhard
- Schurr Frank
- Selaya Garvizu Galia
- Semchenko Marina
- Seymour Colleen
- Sfair Julia C.
- Sharpe Joanne M.
- Sheppard Christine S.
- Sheremetiev Serge
- Shiodera Satomi
- Shipley Bill
- Shovon Tanvir Ahmed
- Siebenkäs Alrun
- Sierra Carlos
- Silva Ana Carolina
- Silva Mateus
- Silva Vasco
- Sitzia Tommaso
- Sjöman Henrik
- Slot Martijn
- Smith Nicholas G.
- Sodhi Darwin
- Soltis Douglas
- Soltis Pamela
- Somers Ben
- Sonnier Grégory
- Sosinski Enio Egon, Jr
- Soudzilovskaia Nadejda A.
- Souza Alexandre F.
- Spasojevic Marko
- Sperandii Marta Gaia
- Stan Amanda B.
- Stegen James
- Steinbauer Klaus
- Stephan Jörg G.
- Sterck Frank
- Stojanovic Dejan B.
- Strydom Tanya
- Suarez Maria Laura
- Svenning Jens‐Christian
- Svitková Ivana
- Svitok Marek
- Svoboda Miroslav
- Swaine Emily
- Swenson Nathan
- Sørensen Mia Vedel
- Tabarelli Marcelo
- Takagi Kentaro
- Tappeiner Ulrike
- Tarifa Rubén
- Tarin Tonantzin
- Tautenhahn Susanne
- Tauugourdeau Simon
- Tavsanoglu Cagatay
- Tedersoo Leho
- Thiffault Nelson
- Thom Dominik
- Thomas Evert
- Thompson Ken
- Thornton Peter E.
- Thuiller Wilfried
- Tichý Lubomír
- Tissue David
- Tjoelker Mark G.
- Tng David Yue Phin
- Tobias Joseph
- Torres‐Ruiz José M.
- Treurnicht Martina
- Trivellone Valeria
- Trolliet Franck
- Trotsiuk Volodymyr
- Tsakalos James L.
- Tsiripidis Ioannis
- Tysklind Niklas
- Tóthmérész Béla
- Török Péter
- Umehara Toru
- Usoltsev Vladimir
- Vadeboncoeur Matthew
- Vaezi Jamil
- Valladares Fernando
- Vamosi Jana
- Van Cleemput Elisa
- Van Meerbeek Koenraad
- Vanderwel Mark
- Vanselow Kim André
- Varone Laura
- Vasquez Valderrama Maribel Yesenia
- Vassilev Kiril
- Vellend Mark
- Veneklaas Erik J.
- Verbeeck Hans
- Verheyen Kris
- Vibrans Alexander
- Vieira Ima
- Villacís Jaime
- Violle Cyrille
- Vivek Pandi
- Vårhammar Angelica
- Wagner Katrin
- Waldram Matthew
- Waldron Anthony
- Walker Anthony P.
- Waller Martyn
- Walther Gabriel
- Wang Feng
- Wang Han
- Wang Weiqi
- Watkins Harry
- Watkins James
- Weber Ulrich
- Weedon James T.
- Weg Martine
- Wei Liping
- Weigelt Patrick
- Weiher Evan
- Wells Aidan W.
- Wellstein Camilla
- Wenk Elizabeth
- Werner Gijsbert D. A.
- Westoby Mark
- Westwood Alana
- White Philip John
- Whitten Mark
- Williams Mathew
- Winkler Daniel E.
- Winter Klaus
- Wirth Christian
- Womack Chevonne
- Wright Ian J.
- Wright Justin
- Wright S. Joseph
- Ximenes Fabiano
- Yamada Toshihiro
- Yamaji Keiko
- Yanai Ruth
- Yankov Nikolay
- Yguel Benjamin
- Zanini Kátia Janaina
- Zanne Amy E.
- Zelený David
- Zhao Yun‐Peng
- Zheng Ji
- Zheng Jingming
- Ziemińska Kasia
- Zirbel Chad R.
- Zizka Georg
- Zotz Gerhard
- Zo‐Bi Irié Casimir
- Öllerer Kinga
- Publication venue
- John Wiley and Sons
- Publication date
- 10/01/2020
- Field of study
Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study
- Author
- Abad Ricardo Diaz
- Abe Toshikazu
- Abroug Fekri
- Adams John C.
- Adamsson Richard O.
- Adolfsson Anne
- Aguilar Ronald Zumaran
- Aguirre Janet S.
- Aguirre-Bermeo Hernan
- Aisa Tharwat M.
- Aisiku Imo
- Ajetunmobi Olaitan O.
- Aker Mustafa
- Akyol Onat O.
- Al Dorzi Hasan M.
- Al Jabbary Ahmed S.
- Albaiceta Guillermo M.
- Albarrak Mohamad M.
- Albiero Daniela
- Alda Rosa S.
- Alejandro Risso V.
- Alexander Peter
- Algaba Ángela
- Aliaga Felipe A.
- Alisasis Alain U.
- Allan Russell M.
- Allue Raquel Montoiro
- Almekhlafi Ghaleb
- Alonso Javier G.
- Altaf Wahid
- Alvarez António M.
- Alvarez Javier
- Amin Pravin
- Amir Fahd
- Amor Abdellatif Benslama Mourad
- An Youzhong
- Andersen Finn H.
- Andoh Kohkichi
- Andruszkiewicz Pawel
- Aneman Anders
- Antonelli Massimo M.
- Antônio Ana Carolina P.
- Aoki Nobumasa
- Appelberg Henrik
- Arabi Yaasen
- Arabi Yaseen M.
- Araujo Ana M.
- Arizmendi Alfons
- Arnal Jean-Michel
- Artiga Maria Jose D.
- Artigas Antonio
- Ascoli Aline
- Au Siu-Ming
- Avila Luis E.
- Azad Raman
- Azevedo Luciano Cesar
- Baboi Loredana
- Badie Julio C.
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- Bailey Mathew B.
- Bajwa Ed
- Balkhi Hicham
- Baltus Thomas
- Banner-Goodspeed Valerie M.
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- Yao Qingchun
- Ye Zheng L.
- Yeatts Dale J.
- Yu Rongguo
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste Luis J.
- Zacharas Giannis A.
- Zacharowski Kai D.
- Zani Gianluca
- Zantua Kim S.
- Zazu Alan
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé O.
- Zhai Zhe
- Zhang Fan
- Zhang Xing Y.
- Zhao Huiying
- Zhao Jun
- Zhao Xian Y.
- Zheng Ruiqiang
- Zhou Fa C.
- Zhou Suming
- Zhu Bao H.
- Zhu Wei H.
- Zogheib Elie H.
- Ñamendys-Silva Silvio A.
- Ünal Necmettin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
- Author
- Aase Handberg
- Abhijna R Ballal
- Abhimanyu Thakur
- Abuelreich Sarah
- Achille Anselmo
- Adam L Maddox
- Adityas Purnianto
- Adrian E Morelli
- Adrian L Harris
- Adriana F Paes Leme
- Adriana T Larregina
- Afrodité Németh
- Afsareen Bano
- Agnieszka Razim
- Agustin Enciso-Martinez
- Ahmed Ge Ibrahim
- Ahmed Somaida
- Aija Linē
- Ainhoa Alberro
- Ajay P Singh
- Akbar L Marzan
- Akhil Srivastava
- Akira Yokoi
- Al Charest
- Alain R Brisson
- Alan J Zimmerman
- Albano Cáceres-Verschae
- Aled Clayton
- Aleksandra Inic-Kanada
- Aleksei Tikhonov
- Alena Ivanova
- Alessandra Ciullo
- Alessandro Gori
- Alessio Noghero
- Alex J Rai
- Alexander Otahal
- Alexander R Ivanov
- Alexis G Murillo Carrasco
- Alice Gualerzi
- Alicia Galinsoga
- Alicia Llorente
- Aliosha I Figueroa-Valdés
- Alireza Fazeli
- Alissa M Weaver
- Alok Raghav
- Alvaro Compañ-Bertomeu
- Amanda Khoo
- Amanda Salviano-Silva
- Amandine Bonifay
- Amankeldi A Salybekov
- Amélie Nadeau
- Amin Zakeri
- Amirmohammad Nasiri Kenari
- Amit K Srivastava
- Amy A Baxter
- Amy C Kauffman
- Amy H Buck
- An Hendrix
- Ana C Torrecilhas
- Ana I Salazar-Puerta
- Ana O'Loghlen
- Anabela Cordeiro-da-Silva
- Anaïs Bécot
- Anders T Boysen
- Andras G Miklosi
- Andras Saftics
- András I Försönits
- Andre J van Wijnen
- Andrea Galisova
- Andrea Ridolfi
- Andrea Zendrini
- Andreas Möller
- Andreia M Silva
- Andreina Schoeberlein
- Andreu Matamoros-Angles
- Andrew Devitt
- Andrew F Hill
- Andrew Lai
- Andrew Rowland
- André Cronemberger-Andrade
- André Görgens
- Andries Zijlstra
- Angela M Zivkovic
- Angelica Ortiz
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- Bahnisikha Barman
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- Batuhan T Bozkurt
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- Sara I Veiga
- Sarah Abuelreich
- Sarah Deville
- Sarah E Glass
- Sarah H Ahmed
- Sarah Williams
- Sarai Martinez-Pacheco
- Saravanakumar Murugesan
- Saroj Kumar
- Sasha J Kweskin
- Saugstad Julie A.
- Saumya Das
- Sayam Ghosal
- Scott M Langevin
- Sean M Davidson
- Seiko Ikezu
- Seoyoon Bae
- Serena Cavallero
- Setty M Magaña
- Seung W Oh
- Sébastien Banzet
- Shalini Mishra
- Sharad Kumar
- Sheila Spada
- Shekari Faezeh
- Sherif A Ibrahim
- Shikha Rani
- Shilpa Buch
- Shin-Ichi Kano
- Shirley Potter
- Shivakumar K Reddy
- Shuai Chen
- Siew Ling Ong
- Sigrun Lange
- Silvia Picciolini
- Silvia Sánchez Martín
- Silvio Kau-Strebinger
- Simon J Powis
- Simon Swift
- Simona Taverna
- Simonides I van de Wakker
- Siyu Chen
- Sneha Raju
- Soazig Le Lay
- Sofija Glamočlija
- Solange Landreville
- Somchai Chutipongtanate
- Sonal Sukreet
- Soo Kim
- Sophie Cavallero
- Sophie Rome
- Soren Jacobsen
- Ssang-Goo Cho
- Stanley M Lemon
- Stanley S Stylli
- Stefan Schneider
- Stefania Raimondo
- Stefano Forte
- Steffi Bosch
- Stella Kourembanas
- Stephanie F Rutter
- Stephanie Jung
- Stephanie M Bollard
- Stephen Lenzini
- Stephen Redenti
- Steven J Biller
- Steven M Jay
- Stuart Hunt
- Subbaya Subramanian
- Subhadip Ghatak
- Sujan K Mondal
- Sujata Mohanty
- Sukhbir Kaur
- Suman Dutta
- Sun Young Lee
- Suresh Mathivanan
- Surya Shrivastava
- Susann Allelein
- Susanne Gabrielsson
- Susanne Krasemann
- Susmita Sahoo
- Suvendra N Bhattacharyya
- Sveva Bollini
- Swasti Tiwari
- Swift Simon
- Sylwia Bobis-Wozowicz
- Syrine Arif
- Tae Ryong Lee
- Taeyoung Kang
- Takahiro Ochiya
- Takanori Eguchi
- Tamás Beke-Somfai
- Tamás Visnovitz
- Tania Limongi
- Tania Martins-Marques
- Tanina Arab
- Tara Thompson-Felix
- Taral R Lunavat
- Tatiane De Rossi
- Tatu Rojalin
- Tecla Marangon
- Teena Kjb Gamage
- Ter‐Ovanesyan Dmitry
- Thabiso E Motaung
- Thanh Kha Phan
- Theresa L Whiteside
- Théry Clotilde
- Thibaud Dauphin
- Thomas Kislinger
- Thomas Michael Shiju
- Thupten Tsering
- Tiana F Koukoulis
- Tijana Jovanovic-Talisman
- Timothea Konstantinou
- Timothy V Domashevich
- Tine Hiorth Schøyen
- Tobias Tertel
- Tom Ap Driedonks
- Tom G Keulers
- Tommaso Neri
- Tomofumi Yamamoto
- Tong Wang
- Torrecilhas Ana C.
- Tosar Juan P.
- Trude Aspelin
- Tsuneya Ikezu
- Ursula S Sandau
- Useckaite Zivile
- Uta Erdbrügger
- Valentina R Minciacchi
- Valentina Zappulli
- Valeria Barreca
- Valle Francesco
- van der Pol Edwin
- van Herwijnen Martijn J. C.
- Varga Zoltan
- Vasiliki Mahairaki
- Vasiliy S Chernyshev
- Vatsal Deliwala
- Veer Bala Gupta
- Vendula Pospichalova
- Vengala Rao Yenuganti
- Venkatesh Kumar Chetty
- Vera A Tang
- Vera Mugoni
- Vera Tscherrig
- Verity J Ford
- Verline Justilien
- Veronica Huber
- Veronika Kralj-Iglic
- Veronika Stoka
- Victor Bodart-Santos
- Vijaya Sunkara
- Vikramsingh Gujar
- Viktoria Szeifert
- Viktoria Weber
- Vincent Hyenne
- Vincent Yeung
- Vincenza Dolo
- Violaine Moreau
- Vito G D'Agostino
- Vivek Kumar Gupta
- Vladimir Bokun
- Vroniqa Ku'ulei-Lyn Faustino
- Vytautas Žėkas
- Wai-Leng Lee
- Wanessa F Altei
- Wauben Marca H. M.
- Wehman Ann M.
- Wei Duan
- Wei Guo
- Wei Seong Toh
- Welsh Joshua A.
- Wen-Wei Chang
- Wilfrid Boireau
- Wilfried W Bazié
- Willem Stoorvogel
- Williams Sarah
- Witwer Kenneth W.
- Wolfgang Holnthoner
- Wyatt N Vreeland
- Xabier Osteikoetxea
- Xandra O Breakefield
- Xavier Loyer
- Xiaomei Yan
- Xiaoqin Wang
- Xinhua Lei
- Xinlei Li
- Xiuming Liang
- Yagmur Yildizhan
- Yang You
- Yasuo Inoshima
- Yi Wen
- Yinghong Zhou
- Yingtang Gao
- Yiyao Huang
- Yoel Sadovsky
- Yohan Kim
- Yong Song Gho
- Yongkang Yang
- Yonis Bare
- Yoon-Kyoung Cho
- Yoshinobu Takakura
- Young-Gyun Park
- Yu Fujita
- Yu Xiao
- Yuki Yamamoto
- Yumi Kumagai
- Yunjie Wu
- Yunxi Chen
- Yusuke Yamamoto
- Yusuke Yoshioka
- Yvan Courageux
- Yvonne Couch
- Zach Troyer
- Zendrini Andrea
- Zheng Lei
- Zheng Zhao
- Zijlstra Andries
- Zimmerman Alan J.
- Zivile Useckaite
- Zoltan Varga
- Zoltán Varga
- Zoltán Wiener
- Zucai Suo
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly
Risk factors for Coronavirus disease 2019 (Covid-19) death in a population cohort study from the Western Cape province, South Africa
- Author
- A Sayed
- Abdurasiet Mowlana
- Abraham J Viljoen
- Adam Boutall
- Alana Heynes
- Alda Vermeulen
- Alexa Heekes
- Alicia Khwitshana
- Alistair Broadhurst
- Allison Moore
- Andre Nortje
- Andrew Boulle
- Annie Lombard
- Anthony Figaji
- Arifa Parker
- Arvin Khamajeet
- Ashely Jacobs
- Ashley Moodley
- Ayanda Mnguni
- Babalwa Ndebele
- Barbra Vermooten
- Boitumelo Mashigo
- Boitumelo Matlapeng
- Brian Allwood
- Bridget Hodkinson
- Bulewa Mbena
- Candice Van Koningsbruggen
- Cari Stek
- Carol Cragg
- Caroline Neumuller
- Catherine Rode
- Cecilia Coccia
- Chadwin Corin
- Chané Paulsen
- Charlene Lawrence
- Che Daniel
- Cheryl Cohen
- Chima Ofoegbu
- Chizama Mnqwazi
- Christoff Hanekom
- Christoffel Botha
- Clint Hendrikse
- Clint Johannes
- Coenraad F N Koegelenberg
- David Marais
- David Pienaar
- De Vries Basson
- Deborah Maughan
- Derick Allen
- Desiree Moodley
- Dion Levin
- Dirk Blom
- Dirkie Claasen
- Dusica Stapar
- Eddy Zitha
- Eduard Langenegger
- Eize Louw
- Elbe Zwanepoel
- Elizabeth Gatley
- Elsa De Bruyn
- Elsabe Smith
- Elzanne Olivier
- Emma Kalk
- Erna Morden
- Ernst Möller
- Ethel Linden-Mars
- Evashan Govender
- Florence Phelanyane
- Francois Maritz
- Francois Roodt
- Frederick Marais
- Funeka Nyengane
- Gabriela Patten
- Gary Maartens
- Gerrit Viljoen
- Gideon Titus
- Gordon Audley
- Gordon Robertson
- Graeme Meintjes
- Graham Fieggan
- Gregory Calligaro
- Hannah Hussey
- Hans Prozesky
- Hassan Mahomed
- Heather Jaspan
- Helen Schneider
- Hennie Sekhukhune
- Henri Pickard
- Hlengani Mathema
- Jacque Le Roux
- Jacqueline Voget
- Jacques Rood
- James Porter
- James Van Duuren
- Jamy-Lee Bam
- Jantjie J Taljaard
- Jean Botha
- Jean Jacque Kruger
- Jeanette Holtzhausen
- Jody Davids
- Joel A Dave
- John Lazarus
- Jon Ambler
- Jonathan Euvrard
- Jonathan Lucas
- Jonathan Naude
- Jonno Vogel
- Jonny Peter
- Joubin Khan
- Juanita Arendse
- Juanita McClaughlin
- Julius Rozmiarek
- Kasturi Buddiga
- Kathleen Bateman
- Kathleen Murie
- Katrin Stuve
- Katya Evans
- Kent Pluke
- Kerrigan McCarthy
- Kerrin Begg
- Kevin Adams
- Kevin Lee
- Kim Anderson
- Kim Laubscher
- Kobie Erasmus
- Lauren Knight
- Le Roux van der Merwe
- Lee Alan Wallis
- Leigh Johnson
- Leilah Najjaar
- Lenny Naidoo
- Liesel Petersen
- Lilian Dudley
- Linda Aldum
- Linda Boloko
- Lisa Boerlage
- Lizanne Victor
- Lucille Blumberg
- Luckmore Muzarabani
- Luthando Vazi
- Luyanda Mbanga
- Lydia Cairncross
- Lynn Morris
- Manqoba Vusumuzi Gule
- Marc Bernon
- Marc Mendelson
- Marc Nortje
- Marie du Preez
- Mariette Smith
- Marije van Schalkwyk
- Mariska Kotze
- Mark Wates
- Martin de Man
- Martin De Villiers
- Mary-Ann Davies
- Masudah Paleker
- Matthias Scriba
- Matthys Henndrik Botha
- Maylene Shung King
- Melanie Shaw
- Michael Held
- Michelle Williams
- Mimi Deetlefs
- Miriam Kahn
- Mogamat Yazied Chothia
- Moosa Parak
- Morna Cornell
- Muideen Bello
- Mumtaz Abbass
- Muzzammil Ismail
- Nabilah Ebrahim
- Naomi Levitt
- Natacha Berkowitz
- Nectarios Papavarnavas
- Nei-yuan Hsiao
- Nelesh Govender
- Nellis van Zyl Smit
- Nesbert Zinyakatira
- Neshaad Schrueder
- Nicki Tiffin
- Nicolene Du Toit
- Nienke van Schaik
- Nisha Jacob
- Nokubonga Vundla
- Nokwanda Sithole
- Nomonde Mbatani
- Nonte Mhlana
- Nosi Kalawe
- Ntobeko Ntusi
- Olina Ngwenya
- Pam Groenewald
- Patience Nyakato
- Patrick Szymanski
- Peter Beckwith
- Peter J Raubenheimer
- Petro Frankenfeld
- Phindile Gina
- Pierre Dane
- Pieter Venter
- Prasun Singh
- Priscilla Tsondai
- Raakhee Girran
- Rachel Carelse
- Remy Daroowala
- Rene Krogscheepers
- René English
- Renée de Waal
- Reshma Kassanjee
- Riaasat Khan
- Richard Osei-Yeboah
- Riezaah Abrahams
- Riyaadh Dawood
- Rizqa Armien
- Robert van den berg
- Rochelle Bailey
- Rochelle Grobler
- Rodgers Manganyi
- Rory Pienaar
- Ruan Marais
- Sa'ad Lahri
- Saadiq Kariem
- Saadiq Moolla
- Sabelo Hlatswayo
- Santhuri Viranna
- Scott Lee Jones
- Sean Burmeister
- Sean Wasserman
- Shakeel Hoosain
- Sharita Kooverjee
- Sheron Forgus
- Shiraaz Gabriel
- Simthandile Mazondwa
- Sipho Dlamini
- Sthembiso Sithole
- Sue Le Roux
- Sumanth Karamchand
- Susan Hugo
- Suzaan Marais
- Suzanne Kuhn
- Tarin Europa
- Taryn Allie
- Tendesayi Kufa
- Thabiet Jardine
- Thania Kahn
- Themba Mutemaringa
- Thina Majola
- Thoko Malaba
- Tholakele Sabela
- Thomas Crede
- Thomas Du Toit
- Tian Van Der Merwe
- Tsaone Tamuhla
- Usha Lalla
- Vanessa Lomas-Marais
- Vanessa Mudaly
- Vanessa Naidoo
- Virginia Zweigenthal
- Vuyolwethu Soldati
- Waasila Jassat
- Washiefa Isaacs
- Werner Viljoen
- Wilhelm Endres
- Yamanya Tembo
- Ziyanda Vundle
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Risk factors for coronavirus disease 2019 (COVID-19) death in sub-Saharan Africa and the effects of human immunodeficiency virus (HIV) and tuberculosis on COVID-19 outcomes are unknown. We conducted a population cohort study using linked data from adults attending public-sector health facilities in the
Western Cape, South Africa. We used Cox proportional hazards models, adjusted for age, sex, location, and comorbidities, to examine the associations between HIV, tuberculosis, and COVID-19 death from 1 March to 9 June 2020 among (1) public-sector “active patients” (≥1 visit in the 3 years before March 2020); (2) laboratory-diagnosed COVID-19 cases; and (3) hospitalized COVID-19
cases. We calculated the standardized mortality ratio (SMR) for COVID-19, comparing adults living with and without HIV using
modeled population estimates.Among 3 460 932 patients (16% living with HIV), 22 308 were diagnosed with COVID-19, of whom 625 died. COVID19 death was associated with male sex, increasing age, diabetes, hypertension, and chronic kidney disease. HIV was associated with
COVID-19 mortality (adjusted hazard ratio [aHR], 2.14; 95% confidence interval [CI], 1.70–2.70), with similar risks across strata of
viral loads and immunosuppression. Current and previous diagnoses of tuberculosis were associated with COVID-19 death (aHR,
2.70 [95% CI, 1.81–4.04] and 1.51 [95% CI, 1.18–1.93], respectively). The SMR for COVID-19 death associated with HIV was 2.39
(95% CI, 1.96–2.86); population attributable fraction 8.5% (95% CI, 6.1–11.1)
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome associated with COVID-19: An Emulated Target Trial Analysis.
- Author
- Abbosh Nathalie
- Abraham Paul
- Achino Chloé
- Ait Oufella Hafid
- Alessandri Claire
- Alexandru Nica
- Amouretti Marc
- Andremont Olivier
- Andreu Pascal
- Anghel Radu
- Annane Djillali
- Argaud Laurent
- Asfar Pierre
- Assefi Mona
- Aubron Cécile
- Aubrun Frédéric
- Auchabie Johann
- Avargues Patrick
- Avenel Alexandre
- Azoulay Elie
- Bajolet Marie-France
- Baldacini Mathieu
- Barbarot Nicolas
- Baron Elodie
- Baudic Thibaut
- Baudry Thomas
- Bavozet Florent
- Bavozet Florent
- Bayle Frédérique
- Beduneau Gaetan
- Begot Emmanuelle
- Beilouny Bassem
- Beloncle François
- Belot Aurélien
- Benchetrit Deborah
- Benhamida Sarah
- Benhamou Michel
- Benzidi Younès
- Bereiziat Marine
- Bergero Nicoletta
- Berteau Florin
- Bertrand Pierre-Jean
- Besse Marie-Catherine
- Beuret Pascal
- Beurton Alexandra
- Beurton Alexandra
- Bigot Christelle
- Bionz Gauthier
- Biston Patrick
- Bitker Laurent
- Blanc Quentin
- Blayau Clarisse
- Blot Rose-Marie
- Bobet Mathieu
- Bodenes Laetitia
- Boiste Fabienne
- Bonnet Nicolas
- Bonnet-Chateau Justine
- Bornstain Caroline
- Bouchet Bruno
- Boudinaud Michel
- Bouglé Adrien
- Bougouin Wulfran
- Bouilland Anne-Laure
- Boukhanza Messabi
- Bouniol François
- Bourdin Gaël
- Bourreau Anna
- Bouteloup Marie
- Bouzat Pierre
- Boyer Déborah
- Brou Marie-Ange
- Bruckert Vincent
- Bruel Cédric
- Bruna Franklin
- Bruneau Amandine
- Bruneel Fabrice
- Brunet Jennifier
- Cadoz Cyril
- Cady Julien
- Cailliez Pauline
- Calus Julien
- Canet Emmanuel
- Cantier Marie
- Capellier Gilles
- Cardinale Mickael
- Carenco Lisa
- Carles Michel
- Carpentier Dorothée
- Carreira Serge
- Carteaux Guillaume
- Casella Claudia
- Castanera Jermy
- Castelain Vincent
- Caulier Thomas
- Causeret Arnaud
- Chaalal Amina
- Chaignat Claire
- Chalumeau Lemoine Ludivine
- Chapelle Thibault
- Charrier Nathanaël
- Charron Cyril
- Charrrier Liliane
- Chaulier Kevin
- Chaussard Maité
- Chelha Riad
- Chelly Jonathan
- Chemouni Franck
- Chiche Jean-Daniel
- Chillet Patrick
- Cholet Clémentine
- Chommeloux Juliette
- Chrisment Anne
- Chudeau Nicolas
- Cohen Yves
- Cointault Olivier
- Colin Gwenhaël
- Collin Anthony
- Combes Alain
- Combes Alain
- Conrad Marie
- Constantin Jean-Michel
- Contou Damien
- Cottrel Marjolaine
- Couadau Emmanuel
- Coudroy Rémi
- Coupez Elisabeth
- Courte Guilhem
- Courtiade Mahler Juliette
- Coutrot Maxime
- Cracco Christophe
- Cravoisy Aurélie
- Damoisel Charles
- Danguy Des Déserts Marc
- Daniel Matthieu
- Dargent Auguste
- Darjent Barbara
- Darmon Michael
- Darreau Cédric
- Dartevel Anaïs
- Daubin Cédric
- Dauger Stéphane
- Daviet Florence
- de la Chapelle Arnaud
- de Prost Nicolas
- de Roquetaillade Charles
- de Roux Quentin
- Debarre Matthieu
- Degoul Samuel
- Dekeyser Thibault
- Delbove Agathe
- Delforge Quentin
- Delignette Marie-Charlotte
- Dellamonica Jean
- Delord Bertrand
- Demarest Elsa
- Demeret Sophie
- Demiri Suela
- Demiselle Julien
- Demoule Alexandre
- Descamps Richard
- Desmeules Isabelle
- Devaquet Jérôme
- Deye Nicolas
- Deyme Jean-Pierre
- Dhelft François
- Diehl Jean-Luc
- Dlala Mohamed
- Donat Nicolas
- Dopeux Loïc
- Dres Martin
- Du Cheyron Damien
- Dubreuil Guillaume
- Dufour Nicolas
- Dupuis Claire
- Durand Michel
- Duranteau Jacques
- Dépret François
- Ebstein Nathan
- Edouard Luyt Charles
- Egreteau Pierre-Yves
- Ehrmann Stéphan
- Elaroussi Djlali
- Emery Malo
- Esnault Pierre
- Etienney Isabelle
- Faguer Stanislas
- Fartoukh Muriel
- Fatséas Jules
- Faure Henri
- Fayolle Pierre-Marie
- Fedun Yannick
- Ferre Alexis
- Ferriere Nicolas
- Feuchere Philippe
- Filippelli Mathilde
- Fillatre Pierre
- Fleury Grégory
- Flurin Laure
- Fontaine Candice
- Foucault Camille
- Frat Jean-Pierre
- Freita-Ramos Santiago
- Frérou Aurélien
- G. Chousterman Benjamin
- Gaci Rostane
- Galbois Arnaud
- Galerneau Louis-Marie
- Gallot Richard
- Garcia Julie
- Garin Aude
- Garnier Marc
- Garret Charlotte
- Garrigou Sonia
- Garçon Pierre
- Gaudry Stéphane
- Gauss Tobias
- Gauthier Caroline
- Gayat Etienne
- Geneau Isabelle
- Gentilhomme Angélie
- Georges Hugues
- Gergaud Soizic
- Gette Sébastien
- Gevrey Vincent
- Giacardi Christophe
- Gibot Sébastien
- Giovannangeli Luana
- Gissot Valérie
- Gobert Florent
- Godier Anne
- Goffin Pierre
- Goncalves Bruno
- Gouin Philippe
- Goutte Sylvie
- Grenot Romaric
- Gros Antoine
- Grégoire Céline
- Guervilly Christophe
- Guilbart Mathieu
- Guillemet Lucie
- Guilmin-Crépon Sophie
- Guitard Pierre-Gildas
- Guitton Christophe
- Guntz Julien
- Gutton Christophe
- Guérot Emmanuel
- Géri Guillaume
- Hage Rabih
- Hajage David
- Hajage David
- Hamada Sophie
- Hariri Geoffroy
- Harrois Anatole
- Hartman Otto
- Hausermann Marie-Hélène
- Hauw-Berlemont Caroline
- Hayon Jan
- Hazera Pascal
- Heming Nicholas
- Her Benoït
- Herbrecht Jean-Etienne
- Heron Anne
- Herzog Nicolas
- Hierle Lucie
- Hinard Sébastien
- Hoffmann Clément
- Hong Tuan Ha Vivien
- Houdou Lucie
- Hraiech Sami
- Huntzinger Julien
- Hérault Marie-Christine
- Ibrahim Amr
- Jacquier Sophie
- Jacquot Audrey
- Jadot Laurent
- Jallot Anne
- Jamme Matthieu
- Jandeaux Louise-Marie
- Jaubert Paul
- Jean-Michel Vanessa
- Jeannot Matthieu
- Jochmans Sébastien
- Joosten Anne
- Joret Aurélie
- Jozwiak Mathieu
- Julien Cungi Pierre
- Jung Camille
- Karoubi Philippe
- Keogh Ruth
- Kerroumi Younes
- Kherchache Aïssa
- Kimmoun Antoine
- Kisoka Grâce
- Knani Lyes
- Kontar Loay
- Kouchit Yanis
- Kuteifan Khaldoun
- l'Her Erwen
- La Combe Béatrice
- Labruyère Marie
- Lacave Guillaume
- Lacherade Jean-Claude
- Lamacz Anna
- Lambermont Bernard
- Lamer Christian
- Lamhaut Lionel
- Lamraoui Meriam
- Lanaspre Bernard
- Lancelot Aymeric
- Landais Mickaël
- Lasocki Sigismond
- Laterrade Thomas
- Lavalard Alexandra
- Lavayssiere Laurence
- Lazard Thierry
- Le Bouar Gurvan
- Le Meur Anthony
- Le Roy Charlotte
- Le Terrier Christophe
- Le Terrier Christophe
- Lebas Eddy
- Lebbah Said
- Lebreton Guillaume
- Leclerc Maxime
- Lecore Marine
- Legay François
- Leger Maxime
- Lejour Gabriel
- Leloup Guillaume
- Lemarie Pierre
- Lena Diane
- Lepecq Raphaël
- Lesieur Olivier
- Levy Bruno
- Levy Michael
- Leyrat Clémence
- Liteaudon Jean-Mathias
- Lombardi Romain
- Lortat-Jacob Brice
- Lory Cécile
- Louis Guillaune
- Lucas Nolwenn
- Macq Pierre-Yves
- Madeux Benjamin
- Maestraggi Quentin
- Malissin Isabelle
- Maquigneau Natacha
- Marcault Clémence
- Marchalot Antoine
- Marchetta Stella
- Marie Maiziere Eve
- Maringe Camille
- Marois Clémence
- Marsac Lucile
- Martino Frédéric
- Masse Anne-Lyse
- Massou Nicole
- Mathais Quentin
- Mathieu Daniel
- Mathonnet Armelle
- Mattei Matthieu
- Mayaux Julien
- Mazard Tessa
- Mazerand Sandie
- Mazeraud Aurélien
- Mazzoni Thierry
- Mebazaa Alexandre
- Mekontso-Dessap Armand
- Mekontso-Dessap Armand
- Mentec Hervé
- Mercat Alain
- Mercat Alain
- Mhamdi Kais
- Michard Baptiste
- Michelin Florian
- Mira Jean Paul
- Mohebbi Amoli Abolfazl
- Moine Pierre
- Monard Céline
- Monchi Mehran
- Mongardon Nicolas
- Mongardon Nicolas
- Monnet Xavier
- Mons Sandrine
- Monsel Antoine
- Montini Florent
- Montravers Philippe
- Mootien Joy
- Morichau-Beauchant Tristan
- Moury Pierre-Henri
- Moyer Jean-Denis
- Muller Laura
- Mégarbane Bruno
- Mégarbane Buno
- Nay Mai-Ahn
- Neuville Mathilde
- Nguyen-Valat Thi My Hue
- Noel Cinderella
- Noel Thibaut
- Nogier Marie-Béatrice
- Noublanche Julie
- Nougue Hélène
- Nseir Saad
- Nseir Saad
- Omar Edris
- Ordan Marie-Amélie
- Ouali Alexandre
- Ouchike Abdel
- Outin Hervé
- P Delaborde Bertrand
- Page Mathieu
- Paillot Jonathan
- Painvin Benoît
- Pajot Olivier
- Palmyre Jessica
- Pardo Emmanuel
- Parzy Gabriel
- Pascal Michel
- Pasem Ahmed
- Pasquier Pierre
- Paugam Burtz Catherine
- Paulet Rémi
- Pavot Arthur
- Pavot Arthur
- Payen Jean-Francois
- Pene Frédéric
- Perez Severine
- Pernet Pierre
- Perrou Maya
- Persichini Romain
- Petua Philippe
- Pham Tài
- Piagnerelli Michael
- Pichereau Claire
- Pignal Sylvain
- Pili Floury Sébastien
- Pillot Jérôme
- Piton Gael
- Pitta Anaïs
- Plantefeve Gaétan
- Plouvier Fabienne
- Poignant Simon
- Pointurier Valentin
- Poirson Florent
- Poissy Julien
- Pommier Christian
- Poupinel Virginie
- Pradel Gaël
- Preau Sébastien
- Prevost Florian
- Primmaz Steve
- Pugin Jérome
- Pujol Wilfried
- Putegnat Jean-Baptiste
- Péron Nicolas
- Quenet Audrey
- Quenot Jean-Pierre
- Quentin Charlotte
- Quintard Hervé
- Rager Gwendoline
- Rahmani Imen
- Ramakers Michel
- Ravan Ramin
- Razazi Keyvan
- Reignier Jean
- Repessé Xavier
- Resiere Dabor
- Rey Brice
- Ricard Jean-Damien
- Ricard Jean-Damien
- Richard Christian
- Richard Jean Christophe
- Ricome Sylvie
- Rimmele Thomas
- Rivera Caroline
- Robaux Marie-Aline
- Robin Nicolas
- Roca-Cerezo Isabel
- Rodriguez Maeva
- Roger Pierre-Alexandre
- Rohaut Benjamin
- Rolle Amélie
- Rosseli Sylvène
- Roth Christian
- Roucaud Nicolas
- Roudau Jean-Baptiste
- Rouleau Stéphane
- Roux Damien
- Roux Delphine
- Runge Isabelle
- Rusel Leon
- Saccheri Clément
- Sacleux Sophe-Caroline
- Saghi Tahar
- Sahraoui Abdlazize
- Saint Jouan Mélanie
- Saison Julien
- Saladin Cécile
- Salmon Gandonniere Charlotte
- Santi Francesca
- Satre-Buisson Lea
- Sauneuf Bertrand
- Savida Anne-Charlotte
- Schaack Emmanuelle
- Schenesse Deborah
- Schmidt Matthieu
- Schmidt Matthieu
- Schnell David
- Schortgen Frédérique
- Schwebel Carole
- Seguin Amélie
- Selves Agathe
- Sen Juliane
- Serpin Laurent
- Setti Jean-Lou
- Sharshar Tarek
- Shi Ruiying
- Sma Nesrine
- Smonig Rolland
- Sophie Le Floch Anne
- Soumagne Thibaud
- Stihle Xavier
- Stoclin Annabelle
- Suh Noémie
- Sumian Claude
- Sylvestre Aude
- Sztrymf Benjamin
- Sément Arnaud
- Série Mathieu
- Tachon Guillaume
- Tachon Guillaume
- Tadie Jean-Marc
- Tamion Fabienne
- Tanaka Sebastien
- Terzi Nicolas
- Teulier Marion
- Textoris Julien
- Thao Ghyslaine
- Thierry Stéphane
- Thill Chloé
- Thouny Romain
- Thouy François
- Thyrault Martial
- Tientcheu Audrey
- Tran Dinh Alexy
- Tran-Van David
- Trebbia Grégoire
- Trouiler Pierre
- Tubach Florence
- Urbina Tomas
- Valette Sarah
- van Vong Ly
- Veber Benoit
- Vettoretti Lucie
- Vezinet Corinne
- Vieillard-Baron Antoine
- Vimpere Damien
- Vincent Arthur
- Vinclair Camille
- Vinclair Marc
- Vinsonneau Christophe
- Violleau Jade
- Vivet Bérengère
- Vivier Emmanuel
- Voicu Sébastian
- Voiriot Guillaume
- W. Thille Arnaud
- Weiss Emmanuel
- Weiss Nicolas
- Werner Marie
- Winiszewski Hadrien
- Yvin Elise
- Zafimahazo Daniel
- Zlotnik Diane
- Zylberfajn Cécile
- Publication venue
- 'American Thoracic Society'
- Publication date
- 01/01/2022
- Field of study
RATIONALE: Whether COVID patients may benefit from extracorporeal membrane oxygenation (ECMO) compared with conventional invasive mechanical ventilation (IMV) remains unknown. OBJECTIVES: To estimate the effect of ECMO on 90-Day mortality vs IMV only Methods: Among 4,244 critically ill adult patients with COVID-19 included in a multicenter cohort study, we emulated a target trial comparing the treatment strategies of initiating ECMO vs. no ECMO within 7 days of IMV in patients with severe acute respiratory distress syndrome (PaO2/FiO2 <80 or PaCO2 ≥60 mmHg). We controlled for confounding using a multivariable Cox model based on predefined variables. MAIN RESULTS: 1,235 patients met the full eligibility criteria for the emulated trial, among whom 164 patients initiated ECMO. The ECMO strategy had a higher survival probability at Day-7 from the onset of eligibility criteria (87% vs 83%, risk difference: 4%, 95% CI 0;9%) which decreased during follow-up (survival at Day-90: 63% vs 65%, risk difference: -2%, 95% CI -10;5%). However, ECMO was associated with higher survival when performed in high-volume ECMO centers or in regions where a specific ECMO network organization was set up to handle high demand, and when initiated within the first 4 days of MV and in profoundly hypoxemic patients. CONCLUSIONS: In an emulated trial based on a nationwide COVID-19 cohort, we found differential survival over time of an ECMO compared with a no-ECMO strategy. However, ECMO was consistently associated with better outcomes when performed in high-volume centers and in regions with ECMO capacities specifically organized to handle high demand. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
- Altaf Abdulmalik
- Altinel Yuksel
- Altiner Saygin
- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
- Amores Remedios Revilla
- Amrayev Sultan
- Anastasiadou Sofia
- Ancans Guntis
- Anderson Caroline
- Andreani Lorenzo
- Andreotti Dario
- Andreuccetti Jacopo
- Andrianakis Alexandros
- Andro Christophe
- Anesi Alexandre
- Angamuthu Stephen
- Angeles Martina Aida
- Angelico Roberta
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angulo Victor Pinto
- Anjum Arfa
- Anjum Muhammad Ayyub
- Annicchiarico Alfredo
- Anoldo Pietro
- Ansaloni Luca
- Anthoulakis Christos
- Antonelli Amedeo
- Anwar Mohamed
- Anwar Sumadi Lukman
- Anwer Mariyah
- Anyanwu Lofty-John
- Apostolou Christos
- Apostolou Konstantinos
- Appiah-Kubi Adu
- Aprea Giovanni
- Arbab Hana
- Archer James
- Ardura Francisco
- Aremu Muyiwa
- Arif Tahera
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- Armatura Giulia
- Armijos Daniel
- Arnaout Ali
- Arnaoutoglou Eleni
- Arnaud Alexis P.
- Arneja Jugpal
- Arrangoiz Rodrigo
- Arshad Muhammad
- Arthur Joshua
- Ashcroft James
- Ashford Bruce
- Ashraf Fariha
- Asiimwe Daniel
- Asirifi Samuel Amoako
- Asla Amir
- Aslam Ramisha
- Aspide Raffaele
- Ataya Karim
- Ateca Ibabe Villalabeitia
- Atici Semra Demirli
- Atis Gokhan
- Atkins William
- Atkinson Kate
- Attwood Joseph
- Auerkari Aino
- Augestad Knut Magne
- Augustin Goran
- Aujayeb Avinash
- Avella Pasquale
- Awad Ahmed K.
- Awad Hadeel
- Awad Rabih
- Awad Selmy
- Ayad Kusay
- Ayana Birhanu
- Aydin Yener
- Ayeni Funbi
- Aytac Erman
- Azab Ahmed
- Azami Rizwan
- Azize Diallo Abdoul
- Azzam Ahmed Y.
- Azzis Olivier
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- Babis George
- Bacalbasa Nicolae
- Badiani Sarit
- Badran Saif
- Baduell Albert
- Baeesa Saleh
- Baertschiger Reto
- Bafaquh Mohammed
- Bahassan Omar Mohammed
- Bahrami-Hessari Michael
- Baia Marco
- Baidoo Ebikela Ivie
- Bailey Karen
- Baili Efstratia
- Bains Lovenish
- Baiocchi Gian Luca
- Baiocchi Glauco
- Baiyewu Lateef Ayodele
- Bajaj Ankur
- Bajunaid Khalid
- Balagobi Balasingam
- Balasubramanian Ishwarya
- Balduzzi Alberto
- Baldwin Alexander
- Balla Andrea
- Balogh Zsolt J.
- Balogun James A.
- Balogun Simon
- Baloyiannis Ioannis
- Ban Vin Shen
- Bandyopadhyay Samik Kumar
- Bandyopadhyay Soham
- Banerjee Sumit
- Banipal Gurpreet Singh
- Banky Balazs
- Bannone Elisa
- Bansal Sujesh
- Barberis Andrea
- Barbosa-Breda Joao
- Bareka Metaxia
- Barišić Tatjana
- Barlas Aziz Mutlu
- Barlow Ciaran
- Barmayehvar Behrad
- Baroffio Paolo
- Barone Mirko
- Barra Fabio
- Barranquero Alberto G.
- Barugola Giuliano
- Basendowah Mohammed
- Bashir Mahmod
- Basnayake Oshan
- Bass Gary Alan
- Basu Somprakas
- Bateman Antony
- Bateman Kellie
- Batista Sylvia
- Batstone Martin
- Bauer Marlies
- Bauset Juan Carlos Catalá
- Bawa Ashvind
- Bawa Sayesha
- Bayhan Hüseyin
- Bayo Heura Llaquet
- Bazzi Nagham
- Beamish Andrew
- Beasley Nigel
- Beatty Jasmine Winter
- Becerra Angel
- Bedada Alemayehu Ginbo
- Bedzhanyan Arkady
- Begum Farzana
- Beisenov Bekzat
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- Bello Usman Mohammed
- Bellés Ana Ciscar
- Belzile Etienne
- Benamar Safia
- Bence Matthew
- Benshetrit Guy
- Bensoltane Khadidja
- Bergkvist David Julià
- Beristain-Hernandez Jose-Luis
- Bernante Paolo
- Bernardi Daniele
- Beron Reinaldo Isaacs
- Berselli Bruno
- Berselli Mattia
- Bertelli Giacomo
- Bertoglio Pietro
- Bertolaccini Luca
- Beswick Daniel
- Bette Birgit
- Bezirci Rifat
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- Bharathan Rasiah
- Bhat Vivek
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- Bianchi Valentina
- Bianco Francesco
- Bianco Giuseppe
- Bijou Walid
- Bilfaqirah Majed
- Biloslavo Alan
- Bin Alhassan Baba Alhaji
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- Bissacco Daniele
- BİŞGİN TAYFUN
- Blair James
- Blanco Jose
- Blencowe Natalie
- Bloemers Frank
- Board Timothy
- Bobak Peter
- Boccalatte Luis
- Boedo Maria Jesus Maroño
- Bohmer Rob
- Boira Mar Achalandabaso
- Boisson Matthieu
- Boligo Sofia
- Bolton William
- Bombardini Cristina
- Bonavina Luigi
- Bonci Eduard-Alexandru
- Bondurri Andrea
- Bonilla Antonio Ramos
- Bonsaana Gilbert Batieka
- Booth L.
- Borg Elaine
- Borges Miguel Fróis
- Borges Nuno
- Bork Ulrich
- Borselle Dominika
- Bortul Marina
- Botelho Pedro
- Bottari Andrea
- Bouchagier Konstantinos
- Bouliaris Konstantinos
- Bowan Antoinette Bediako
- Bowen Joel
- Bozbiyik Osman
- Bracale Umberto
- Brachini Gioia
- Bramis Konstantinos
- Branagan Graham
- Branzan Daniela
- Brasset Camille
- Bratus Dejan
- Bravo Ana Maria Minaya
- Bravo Sybil Lizanne
- Bright Tim
- Brisinda Giuseppe
- Brodkin Edgar
- Broglia Alessandro
- Brolese Alberto
- Browning Rebecca
- Bruzzaniti Placido
- Brzeszczyński Filip
- Bsisu Isam
- Bua Emmanuel
- Budd Gabrielle
- Bukhari Syed Imran
- Bulian Dirk Rolf
- Bumbasirevic Uros
- Bumber Boris
- Burgos-Blasco Barbara
- Burlov Nikita
- Bussu Francesco
- Bàmbina Fabrizio
- Börner Nikolaus
- Böttcher Arne
- Cabeza Leticia
- Cabrera Marino
- Cais Simon
- Cakmak Guldeniz Karadeniz
- Calabretto Francesca
- Calabrò Marcello
- Calavia Pablo
- Calculli Federica
- Calini Giacomo
- Callan Rory
- Callcut Rachael
- Calu Valentin
- Calvache Jose Andres
- Calvache Nieto
- Calvo Francisco Javier Redondo
- Cama Jitoko
- Camacho Barbosa
- Camarena Ana Isabel Avellaneda
- Camargo-Parra Katherin
- Cammarata Emanuele
- Cammarata Francesco
- Cammarata Roberto
- Campagnaro Tommaso
- Campanelli Michela
- Campennì Paola
- Campisi Giuseppina
- Campo Flaminia
- Campuzano Nicolas
- Cano-Trigueros Emiliano
- Capella Stefano
- Capitan-Morales Luis-Cristobal
- Capobianco Mattia
- Capolupo Gabriella Teresa
- Capozzi Enrico
- Cappuccio Micaela
- Capuano Marianna
- Carannante Filippo
- Carbone Fabio
- Carbone Ludovico
- Caretto Marta
- Caricato Chiara
- Caricato Marco
- Carpenter Holly
- Carreras-Castañer Anna
- Carretero Manuel Moriche
- Caruana Edward J.
- Carvello Michele
- Casagranda Biagio
- Cassese Gianluca
- Cassinotti Elisa
- Castagnini Francesco
- Castaldi Antonio
- Castaño Mario
- Castaño-Leon Ana M.
- Castillo Dayan Fanery Campino
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- Castro Ernes John
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- Caubet Maria Mercedes
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- Colombari Renan Carlo
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- Croghan Stefanie M.
- Cross George W. V.
- Cruz Ricardo Pedrini
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- Cullinane Carolyn
- Cullis Paul
- Cunha Miguel F.
- Cunningham Brian
- Currò Giuseppe
- Cuthbert Rory
- Cutmore Carina
- Czako Ladislav
- Cáceres Freud
- D'Acapito Fabrizio
- D'Addino José Luis
- D'Amico Alessia
- D'Amore Anna
- D'Andrea Giancarlo
- D'Archi Sabatino
- D'Oria Mario
- D'Sa Prashanth
- Daddi Niccolo'
- Dagklis Themistoklis
- Dajani Khaled
- Dajti Irida
- Daketsey Elorm
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- Dare Anna
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- Das Sunit
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- Davidescu Mihnea
- Davies Jessica
- Davies Mark
- Davies Richard Justin
- Davis Amelia
- Dawson Amanda Caroline
- Dawson Jonathon
- Dbouk Samer
- De Alarcón Jaime Rodríguez
- De Andrés-Asenjo Beatriz
- De Bacco Marangon Gustavo
- De Campos Prado Caio Antonio
- De Cillia Michael
- De Haro Jorge Irene
- De Haro Joaquin
- De Jesus Labrador Hernandez Gregorio
- De La Infiesta García Carlos
- De La Medina Antonio Ramos
- De La Rosa-Estadella Marta
- De Nardi Paola
- De Oliveira Gabriel Paiva
- De Pastena Matteo
- De Simone Veronica
- De Sousa Álvaro Francisco Lopes
- De Vega Sánchez Blanca
- De Virgilio Armando
- De Zuanni Marco
- Dean Yomna
- Degarege Dawit
- Degener Stephan
- Dejeu George
- Del Amo María Dolores Arribas
- Dell Angela
- Demetrashvili Zaza
- Demetriades Andreas K
- Demetriou Charis
- Demir Sebahattin
- Dennis Rory
- Deputy Mohammed
- Derilo Habtamu
- Des Déserts Marc Danguy
- Desai Chaitya
- Desio Matteo
- Dessalegn Megbar
- Devarakonda Sreekar
- Dewan Michael
- Dewan Varun
- Dhaity Guipson Dhaity
- Dhondt Bert
- Di Bartolomeo Mattia
- Di Franco Gregorio
- Di Lascio Pierpaolo
- Di Martino Marcello
- Di Nuzzo Maria Michela
- Diaconescu Bogdan
- Dickson Kathryn
- Diehl Thomas
- Dif Elmes Saoussene
- Dimas Angelos
- Dimitrokallis Nikolaos
- Dincer Müserref Beril
- Dindyal Shiva
- Djama Zakarya
- Djedovic Gabriel
- Doerner Johannes
- Doherty Daniel
- Dolci Giampiero
- Domanin Maurizio
- Domingo Marta María Arroyo
- Dominguez-Rosado Ismael
- Don Cristine Pathirannehalage
- Donkin Ian
- Donmez Emin Erhan
- Donoghue Sophie
- Donovan Richard
- Dornseifer Mamun David
- Dorovinis Panagiotis
- Douglas Deborah
- Downey Candice
- Doyle Alex
- Doǧan Lütfi
- Dragisic Vedran
- Draman Mohd Rusdi
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- Dreger Nici Markus
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- Dyas Adam
- Dzhumabaev Khasan
- Dziakova Jana
- Dzogbefia Mawutor
- Díaz Jeancarlos Trujillo
- Dölker Theresa
- Eardley Nicola
- Ebrahim Abdulla
- Echieh Chidiebere Peter
- Edwards John
- Efetov Sergey
- Efremov Sergey
- Egan Richard
- Eiras Miguel Angel Freiria
- Eisa Elamin
- Ekor Oluwayemisi
- Ekwen Gerald
- Ekwunife Okechukwu Hyginus
- El Assaad Hadi
- El Boghdady Michael
- El Tayeb Essam Eldien Abuobaida Banaga Hag
- El-Boghdadly Kariem
- El-Hussuna Alaa
- El-Kassas Mohamed
- Elagili Ahmed
- Elahi Zain
- Elbadawy Merihan A.
- Elbahnasawy Mohamed
- Elbe Peter
- Elboraei Rahma
- Eldabaa Mohamed
- Elebute Olumide
- Elfeki Hossam
- Elfiky Mahmoud
- Elgazar Amr
- Elghadban Hosam
- Elhadi Muhammed
- Elhassan Wael Atif Fadl
- Elkazaz Ahmed
- Ellafi Amera Ali Dakheel
- Elliot R.
- Elnour Moheyaldien Ahmed Elamin
- Elsadek Menan
- Elsahli Saifaleslam
- Elsalhawy Shady
- Elsayem Karam
- Elshahawy Mahmoud Abdelaziz Mohamed
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- Meara John G.
- Meead Adullah
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- Pinney L.
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- Watcyn-Jones Tom
- Waterson Ben
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- Watson Matthew
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- Wilkins Alex
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- Williams Shekinah
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- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
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- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
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