110 research outputs found
1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer
- Author
- A Biederbick
- A Herman-Antosiewicz
- A Yamamoto
- AL Edinger
- AR Kristal
- Arthur E Frankel
- C Hong
- C Hong
- C Qin
- CE Clay
- CJ Grubbs
- CL Chaffer
- CM Cover
- CW Shiau
- DM Ray
- E Elstner
- E Mueller
- EJ Kim
- F Scarlatti
- G Murillo
- Gayathri Chadalapaka
- HL Bradlow
- I Chen
- Indira Jutooru
- J Debnath
- J Hong
- JH Cohen
- JW Huang
- K Vanderlaag
- K Vanderlaag
- Kathy Vanderlaag
- KW Rahman
- LN Kolonel
- M Abdelrahim
- M Gorka
- M Hoyer-Hansen
- M Lamparska-Przybysz
- M Pedro
- MM Bhuiyan
- N Mizushima
- P Lei
- PL Kuo
- R Butler
- Robert C Burghardt
- Rola Barhoumi
- S Chintharlapalli
- S Chintharlapalli
- S Chintharlapalli
- S Chintharlapalli
- S Chintharlapalli
- S Paglin
- S Paglin
- S Pattingre
- S Shimizu
- SM Zhang
- SR Chinni
- Stephen Safe
- T Kanzawa
- T Kanzawa
- T Tanaka
- W Bursch
- W Kassouf
- W Motomura
- WX Zong
- Y Chen
- Y Ichimura
- Y Kabeya
- Y Shao
- Yunpeng Su
- Publication venue
- BioMed Central
- Publication date
- 01/01/2010
- Field of study
Anatomy of the sign-problem in heavy-dense QCD
- Author
- Adam E Romero
- Aranda C Padilla
- Arjanovic MM
- Armadans R Caminal
- Astigarraga ME Pozo
- Barajas CA Chavez
- Bechtle P
- Beck HP
- Becker K
- Becker M
- Beckingham M
- Becot C
- Beddall A
- Beddall AJ
- Bednyakov VA
- Bedognetti M
- Bee CP
- Beemster LJ
- Beermann TA
- Begel M
- Behr JK
- Belanger-Champagne C
- Bell AS
- Bella G
- Bellagamba L
- Bellerive A
- Bellomo M
- Belotskiy K
- Beltramello O
- Belyaev NL
- Benary O
- Benchekroun D
- Bender M
- Bendtz K
- Benekos N
- Benhammou Y
- Benitez J
- Benjamin DP
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Berge D
- Berger N
- Berghaus F
- Beringer J
- Berlendis S
- Berlingen J Montejo
- Bernard NR
- Bernius C
- Bernlochner FU
- Berry T
- Berta P
- Bertella C
- Bertoli G
- Bertolucci F
- Bertram IA
- Bertsche C
- Bertsche D
- Besjes GJ
- Bessner M
- Besson N
- Betancourt C
- Bethke S
- Bevan AJ
- Bhimji W
- Bianchi RM
- Bianchini L
- Bianco M
- Biebel O
- Biedermann D
- Bielski R
- Biesuz NV
- Biglietti M
- Bilokon H
- Bindi M
- Binet S
- Bingul A
- Bini C
- Biondi S
- Bjergaard DM
- Black CW
- Black JE
- Black KM
- Blackburn D
- Blair RE
- Blanchard J-B
- Blanco JE
- Blazek T
- Bloch I
- Blocker C
- Blum W
- Blumenschein U
- Blunier S
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Bock C
- Boehler M
- Boeriu OE Vickey
- Boerner D
- Bogaerts JA
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bold T
- Boldea V
- Boldyrev AS
- Bomben M
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- Boonekamp M
- Borisov A
- Borissov G
- Bortfeldt J
- Bortoletto D
- Bortolotto V
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- Boscherini D
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- Bossio Sola JD
- Boudreau J
- Bouffard J
- Bouhova-Thacker EV
- Boumediene D
- Bourdarios C
- Bousson N
- Boutle SK
- Boveia A
- Boyd J
- Boyko IR
- Bracinik J
- Brandt A
- Brandt G
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- Chernyatin V
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- Correia AM Henriques
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- Crawley SJ
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- de Andrade Filho L Manhaes
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- De Benedetti A
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- Zurzolo G
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
QCD at finite densities of heavy quarks is investigated
using the density-of-states method. The phase factor
expectation value of the quark determinant is calculated to
unprecedented precision as a function of the chemical potential.
Results are validated using those from a reweighting
approach where the latter can produce a significant signalto-noise
ratio. We confirm the particle–hole symmetry at low
temperatures, find a strong sign problem at intermediate values
of the chemical potential, and an inverse Silver Blaze
feature for chemical potentials close to the onset value: here,
the phase-quenched theory underestimates the density of the
full theory
Searches for Higgs boson pair production in the hh→bbττ, γγWW∗, γγbb, bbbb channels with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
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- Zivkovic L
- Zobernig G
- Zoccoli A
- Zurzolo G
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2015
- Field of study
Searches for both resonant and nonresonant Higgs boson pair production are performed in the hh→bbττ, γγWW∗ final states using 20.3 fb−1 of pp collision data at a center-of-mass energy of 8 TeV recorded with the ATLAS detector at the Large Hadron Collider. No evidence of their production is observed and 95% confidence-level upper limits on the production cross sections are set. These results are then combined with the published results of the hh→γγbb, bbbb analyses. An upper limit of 0.69 (0.47) pb on the nonresonant hh production is observed (expected), corresponding to 70 (48) times the SM gg→hh cross section. For production via narrow resonances, cross-section limits of hh production from a heavy Higgs boson decay are set as a function of the heavy Higgs boson mass. The observed (expected) limits range from 2.1 (1.1) pb at 260 GeV to 0.011 (0.018) pb at 1000 GeV. These results are interpreted in the context of two simplified scenarios of the Minimal Supersymmetric Standard Model
Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial
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- Abbas J
- Abbate A
- Abdullakutty J
- Abhyanakar AD
- Aboyans V
- Abrantes JAM
- Abu-Fadel M
- Acevedo M
- Adamkova V
- Adhyapak S
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- Aidar Ayoub JC
- Airaksinen JK
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- Akhter F
- Ako J
- Akright L
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- Al-Windy NYY
- Alan D
- Alcocer Gamba MA
- Alexander JH
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- Alexandru TM
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- Zuniga JDH
- Zurakowski A
- Zuran I
- Zweiker R
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2019
- Field of study
Aims The third Universal Definition of Myocardial Infarction (MI) Task Force classified MIs into five types: Type 1, spontaneous; Type 2, related to oxygen supply/demand imbalance; Type 3, fatal without ascertainment of cardiac biomarkers; Type 4, related to percutaneous coronary intervention; and Type 5, related to coronary artery bypass surgery. Low-density lipoprotein cholesterol (LDL-C) reduction with statins and proprotein convertase subtilisin–kexin Type 9 (PCSK9) inhibitors reduces risk of MI, but less is known about effects on types of MI. ODYSSEY OUTCOMES compared the PCSK9 inhibitor alirocumab with placebo in 18 924 patients with recent acute coronary syndrome (ACS) and elevated LDL-C (≥1.8 mmol/L) despite intensive statin therapy. In a pre-specified analysis, we assessed the effects of alirocumab on types of MI. Methods and results Median follow-up was 2.8 years. Myocardial infarction types were prospectively adjudicated and classified. Of 1860 total MIs, 1223 (65.8%) were adjudicated as Type 1, 386 (20.8%) as Type 2, and 244 (13.1%) as Type 4. Few events were Type 3 (n = 2) or Type 5 (n = 5). Alirocumab reduced first MIs [hazard ratio (HR) 0.85, 95% confidence interval (CI) 0.77–0.95; P = 0.003], with reductions in both Type 1 (HR 0.87, 95% CI 0.77–0.99; P = 0.032) and Type 2 (0.77, 0.61–0.97; P = 0.025), but not Type 4 MI. Conclusion After ACS, alirocumab added to intensive statin therapy favourably impacted on Type 1 and 2 MIs. The data indicate for the first time that a lipid-lowering therapy can attenuate the risk of Type 2 MI. Low-density lipoprotein cholesterol reduction below levels achievable with statins is an effective preventive strategy for both MI types.For complete list of authors see http://dx.doi.org/10.1093/eurheartj/ehz299</p
Performance of the ATLAS muon trigger in pp collisions at [Formula: see text] TeV
- Author
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- Abdallah J
- Abdel Khalek S
- Abdinov O
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- AbouZeid OS
- Abramowicz H
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- Acharya BS
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- Adelman J
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- Agatonovic-Jovin T
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- Agustoni M
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akimoto G
- Akimov AV
- Alberghi GL
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- Alconada Verzini MJ
- Aleksa M
- Aleksandrov IN
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- Alexandre G
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- Alimonti G
- Alio L
- Alison J
- Allbrooke BM
- Allison LJ
- Allport PP
- Almond J
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- Alviggi MG
- Amako K
- Amaral Coutinho Y
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- Amoroso S
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- Amundsen G
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- Andari N
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- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Angelidakis S
- Angelozzi I
- Anger P
- Angerami A
- Anghinolfi F
- Anisenkov AV
- Anjos N
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- Antonaki A
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- Antonov A
- Antos J
- Anulli F
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- Aperio Bella L
- Apolle R
- Arabidze G
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- Arce AT
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- Argyropoulos S
- Arik M
- Armbruster AJ
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- Arratia M
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- Artamonov A
- Artoni G
- Asai S
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- Ashkenazi A
- Asquith L
- Assamagan K
- Astalos R
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- Publication venue
- Publication date
- 01/03/2015
- Field of study
The performance of the ATLAS muon trigger system is evaluated with proton-proton collision data collected in 2012 at the Large Hadron Collider at a centre-of-mass energy of 8 TeV. It is primarily evaluated using events containing a pair of muons from the decay of [Formula: see text] bosons. The efficiency of the single-muon trigger is measured for muons with transverse momentum [Formula: see text] GeV, with a statistical uncertainty of less than 0.01 % and a systematic uncertainty of 0.6 %. The [Formula: see text] range for efficiency determination is extended by using muons from decays of [Formula: see text] mesons, [Formula: see text] bosons, and top quarks. The muon trigger shows highly uniform and stable performance. The performance is compared to the prediction of a detailed simulation
Electron reconstruction and identification efficiency measurements with the ATLAS detector using the 2011 LHC proton–proton collision data
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
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- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
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- Zhemchugov A
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- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann R
- Zimmermann S
- Zimmermann S
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- Ziolkowski M
- Zitoun R
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zurzolo G
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Many of the interesting physics processes to be measured at the LHC have a signature involving one or more isolated electrons. The electron reconstruction and identification efficiencies of the ATLAS detector at the LHC have been evaluated using proton–proton collision data collected in 2011 at s√=7 TeV and corresponding to an integrated luminosity of 4.7 fb −1. Tag-and-probe methods using events with leptonic decays of W and Z bosons and J/ψ mesons are employed to benchmark these performance parameters. The combination of all measurements results in identification efficiencies determined with an accuracy at the few per mil level for electron transverse energy greater than 30 GeV
Search for Higgs and Z Boson Decays to J/ψγ and ϒ(nS)γ with the ATLAS Detector.
- Author
- (ATLAS Collaboration)
- Aad G
- Abbott B
- Abdallah J
- Abdel Khalek S
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Agatonovic-Jovin T
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akimoto G
- Akimov AV
- Alberghi GL
- Albert J
- Albrand S
- Alconada Verzini MJ
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Alimonti G
- Alio L
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Aloisio A
- Alonso A
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- Altheimer A
- Alvarez Gonzalez B
- Alviggi MG
- Amako K
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- Amelung C
- Amidei D
- Amor Dos Santos SP
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- Amram N
- Amundsen G
- Anastopoulos C
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- Andari N
- Andeen T
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- Andrei V
- Anduaga XS
- Angelidakis S
- Angelozzi I
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- Anghinolfi F
- Anisenkov AV
- Anjos N
- Annovi A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Aperio Bella L
- Arabidze G
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- Araque JP
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- Arslan O
- Artamonov A
- Artoni G
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- Ashkenazi A
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- Ayoub MK
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- Barak L
- Baranov SP
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- Borisov A
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- Britton D
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- Buckley AG
- Buda SI
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- Yan Z
- Yang H
- Yang H
- Yang Y
- Yanush S
- Yao L
- Yao W-M
- Yasu Y
- Yatsenko E
- Yau Wong KH
- Ye J
- Ye S
- Yeletskikh I
- Yen AL
- Yildirim E
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJS
- Youssef S
- Yu DR
- Yu J
- Yu J
- Yu JM
- Yuan L
- Yurkewicz A
- Yusuff I
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zaman A
- Zambito S
- Zanello L
- Zanzi D
- Zeitnitz C
- Zeman M
- Zemla A
- Zengel K
- Zenin O
- Zerwas D
- Zhang D
- Zhang F
- Zhang J
- Zhang L
- Zhang R
- Zhang X
- Zhang Z
- Zhao X
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou C
- Zhou L
- Zhou L
- Zhou N
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann R
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zobernig G
- Zoccoli A
- Zur Nedden M
- Zurzolo G
- Zwalinski L
- Åkesson TPA
- Åsman B
- Ženiš T
- Živković L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2015
- Field of study
A search for the decays of the Higgs and Z bosons to J/ψγ and ϒ(nS)γ (n=1,2,3) is performed with pp collision data samples corresponding to integrated luminosities of up to 20.3 fb^{-1} collected at sqrt[s]=8 TeV with the ATLAS detector at the CERN Large Hadron Collider. No significant excess of events is observed above expected backgrounds and 95% C.L. upper limits are placed on the branching fractions. In the J/ψγ final state the limits are 1.5×10^{-3} and 2.6×10^{-6} for the Higgs and Z boson decays, respectively, while in the ϒ(1S,2S,3S)γ final states the limits are (1.3,1.9,1.3)×10^{-3} and (3.4,6.5,5.4)×10^{-6}, respectively.We acknowledge the support of ANPCyT,
Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI,
Canada; CERN; CONICYT, Chile; CAS, MOST and
NSFC, China; COLCIENCIAS, Colombia; MSMT CR,MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/ IRFU, France; GNSF, Georgia; BMBF, DFG, HGF,
MPG and AvH Foundation, Germany; GSRT and
NSRF, Greece; ISF, MINERVA, GIF, I-CORE and
Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS,
Japan; CNRST, Morocco; FOM and NWO, Netherlands;BRF and RCN, Norway; MNiSW and NCN, Poland;GRICES and FCT, Portugal; MNE/IFA, Romania; MES of Russia and ROSATOM, Russian Federation; JINR;MSTD, Serbia; MSSR, Slovakia; ARRS and MIZŠ, Slovenia; DST/NRF, South Africa; MINECO, Spain;SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC,Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America
Search for resonances in diphoton events at √s = 13 TeV with the ATLAS detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Abeloos B
- Aben R
- Abouzeid Os
- Abraham Nl
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya Bs
- Adamczyk L
- Adams Dl
- Adelman J
- Adomeit S
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- Agatonovic-Jovin T
- Agricola J
- Aguilar-Saavedra Ja
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- Ahmadov F
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- Akesson Tpa
- Akimov Av
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- Aleksa M
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- Alexa C
- Alexander G
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- Allbrooke Bmm
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- Busato E
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- Buttar Cm
- Butterworth Jm
- Butti P
- Buttinger W
- Buzatu A
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- Cabrera Urban S
- Caforio D
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- Calafiura P
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- Calderini G
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- Cantrill R
- Cao T
- Capeans Garrido Mdm
- Caprini I
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- Capua M
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- Carbone Rm
- Cardarelli R
- Cardillo F
- Carli I
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- Carlino G
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- Carrillo-Montoya Gd
- Carter Jr
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- Casadei D
- Casado Mp
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- Castelli A
- Castillo Gimenez V
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- Caudron J
- Cavaliere V
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- Cavalli D
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- Hard As
- Harenberg T
- Hariri F
- Harkusha S
- Harrington Rd
- Harrison Pf
- Hartjes F
- Hartmann Nm
- Hasegawa M
- Hasegawa Y
- Hasib A
- Hassani S
- Haug S
- Hauser R
- Hauswald L
- Havranek M
- Hawkes Cm
- Hawkings Rj
- Hayakawa D
- Hayden D
- Hays Cp
- Hays Jm
- Hayward Hs
- Haywood Sj
- Head Sj
- Heck T
- Hedberg V
- Heelan L
- Heim S
- Heim T
- Heinemann B
- Heinrich Jj
- Heinrich L
- Heinz C
- Hejbal J
- Helary L
- Hellman S
- Helsens C
- Henderson J
- Henderson Rcw
- Heng Y
- Henkelmann S
- Henriques Correia Am
- Henrot-Versille S
- Herbert Gh
- Herget V
- Hernandez Jimenez Y
- Herten G
- Hertenberger R
- Hervas L
- Hesketh Gg
- Hessey Np
- Hetherly Jw
- Hickling R
- Higon-Rodriguez E
- Hill E
- Hill Jc
- Hiller Kh
- Hillier Sj
- Hinchliffe I
- Hines E
- Hinman Rr
- Hirose M
- Hirschbuehl D
- Hobbs J
- Hod N
- Hodgkinson Mc
- Hodgson P
- Hoecker A
- Hoeferkamp Mr
- Hoenig F
- Hohn D
- Holmes Tr
- Homann M
- Hong Tm
- Hooberman Bh
- Hopkins Wh
- Horii Y
- Horton Aj
- Hostachy J-
- Hou S
- Hoummada A
- Howarth J
- Hrabovsky M
- Hristova I
- Hrivnac J
- Hryn'Ova T
- Hrynevich A
- Hsu C
- Hsu Pj
- Hsu S-
- Hu D
- Hu Q
- Hu S
- Huang Y
- Hubacek Z
- Hubaut F
- Huegging F
- Huffman Tb
- Hughes Ew
- Hughes G
- Huhtinen M
- Huo P
- Huseynov N
- Huston J
- Huth J
- Iacobucci G
- Iakovidis G
- Ibragimov I
- Iconomidou-Fayard L
- Ideal E
- Idrissi Z
- Iengo P
- Igonkina O
- Iizawa T
- Ikegami Y
- Ikeno M
- Ilchenko Y
- Iliadis D
- Ilic N
- Ince T
- Introzzi G
- Ioannou P
- Iodice M
- Iordanidou K
- Ippolito V
- Ishijima N
- Ishino M
- Ishitsuka M
- Ishmukhametov R
- Issever C
- Istin S
- Ito F
- Iturbe Ponce Jm
- Iuppa R
- Iwanski W
- Iwasaki H
- Izen Jm
- Izzo V
- Jabbar S
- Jackson B
- Jackson P
- Jain V
- Jakobi Kb
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- Jakobsen S
- Jakoubek T
- Jamin Do
- Jana Dk
- Jansen E
- Jansky R
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- Jarlskog G
- Javadov N
- Javurek T
- Jeanneau F
- Jeanty L
- Jejelava J
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- Jennens D
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- Ji H
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- Jimenez Pena J
- Jin S
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- Jorge Pm
- Jovicevic J
- Ju X
- Juste Rozas A
- Kaczmarska A
- Kado M
- Kagan H
- Kagan M
- Kahn Sj
- Kaji T
- Kajomovitz E
- Kalderon Cw
- Kaluza A
- Kama S
- Kamenshchikov A
- Kanaya N
- Kaneti S
- Kanjir L
- Kantserov Va
- Kanzaki J
- Kaplan B
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- Kapliy A
- Kar D
- Karakostas K
- Karamaoun A
- Karastathis N
- Kareem Mj
- Karentzos E
- Karnevskiy M
- Karpov Sn
- Karpova Zm
- Karthik K
- Kartvelishvili V
- Karyukhin An
- Kasahara K
- Kashif L
- Kass Rd
- Kastanas A
- Kataoka Y
- Kato C
- Katre A
- Katzy J
- Kawagoe K
- Kawamoto T
- Kawamura G
- Kazanin Vf
- Keeler R
- Kehoe R
- Keller Js
- Kempster Jj
- Kentaro K
- Keoshkerian H
- Kepka O
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- Kersten S
- Keyes Ra
- Khader M
- Khalil-zada F
- Khanov A
- Kharlamov Ag
- Khoo Tj
- Khovanskiy V
- Khramov E
- Khubua J
- Kido S
- Kilby Cr
- Kim Hy
- Kim Sh
- Kim Yk
- Kimura N
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- King M
- King Sb
- Kirk J
- Kiryunin Ae
- Kishimoto T
- Kisielewska D
- Kiss F
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- Kivernyk O
- Kladiva E
- Klein M
- Klein Mh
- Klein U
- Kleinknecht K
- Klimek P
- Klimentov A
- Klingenberg R
- Klinger Ja
- Klioutchnikova T
- Kluge E-
- Kluit P
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- Knue A
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- Kodys P
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- Koffas T
- Koffeman E
- Kohler Mk
- Koi T
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- Kolb M
- Koletsou I
- Komar Aa
- Komori Y
- Kondo T
- Kondrashova N
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- Konig Ac
- Kono T
- Konoplich R
- Konstantinidis N
- Kopeliansky R
- Koperny S
- Kopke L
- Kopp Ak
- Korcyl K
- Kordas K
- Korn A
- Korol Aa
- Korolkov I
- Korolkova Ev
- Kortner O
- Kortner S
- Kosek T
- Kostyukhin Vv
- Kotwal A
- Kourkoumeli-Charalampidi A
- Kourkoumelis C
- Kouskoura V
- Kowalewska Ab
- Kowalewski R
- Kowalski Tz
- Kozakai C
- Kozanecki W
- Kozhin As
- Kramarenko Va
- Kramberger G
- Krasnopevtsev D
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- Kravchenko A
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- Kuechler Jt
- Kuehn S
- Kugel A
- Kuger F
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- Kukla R
- Kulchitsky Y
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- Lavrijsen W
- Law At
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- Lazovich T
- Lazzaroni M
- Le Dortz O
- Le Guirriec E
- Le Quilleuc Ep
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- Lecompte T
- Ledroit-Guillon F
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- Leggett C
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- Lei X
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- Lellouch D
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Searches for new resonances decaying into two photons in the ATLAS experiment at the CERN Large Hadron Collider are described. The analysis is based on proton-proton collision data corresponding to an integrated luminosity of 3.2 fb−1 at s√=13 TeV recorded in 2015. Two searches are performed, one targeted at a spin-2 particle of mass larger than 500 GeV, using Randall-Sundrum graviton states as a benchmark model, and one optimized for a spin-0 particle of mass larger than 200 GeV. Varying both the mass and the decay width, the most significant deviation from the background-only hypothesis is observed at a diphoton invariant mass around 750 GeV with local significances of 3.8 and 3.9 standard deviations in the searches optimized for a spin-2 and spin-0 particle, respectively. The global significances are estimated to be 2.1 standard deviations for both analyses. The consistency between the data collected at 13 TeV and 8 TeV is also evaluated. Limits on the production cross section times branching ratio to two photons for the two resonance types are reported
Effect of alirocumab on mortality after acute coronary syndromes. An analysis of the ODYSSEY OUTCOMES randomized clinical trial
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- Zeiher AM
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- Zweiker R
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 04/01/2019
- Field of study
Background: Previous trials of PCSK9 (proprotein convertase subtilisin-kexin type 9) inhibitors demonstrated reductions in major adverse cardiovascular events, but not death. We assessed the effects of alirocumab on death after index acute coronary syndrome. Methods: ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) was a double-blind, randomized comparison of alirocumab or placebo in 18 924 patients who had an ACS 1 to 12 months previously and elevated atherogenic lipoproteins despite intensive statin therapy. Alirocumab dose was blindly titrated to target achieved low-density lipoprotein cholesterol (LDL-C) between 25 and 50 mg/dL. We examined the effects of treatment on all-cause death and its components, cardiovascular and noncardiovascular death, with log-rank testing. Joint semiparametric models tested associations between nonfatal cardiovascular events and cardiovascular or noncardiovascular death. Results: Median follow-up was 2.8 years. Death occurred in 334 (3.5%) and 392 (4.1%) patients, respectively, in the alirocumab and placebo groups (hazard ratio [HR], 0.85; 95% CI, 0.73 to 0.98; P=0.03, nominal P value). This resulted from nonsignificantly fewer cardiovascular (240 [2.5%] vs 271 [2.9%]; HR, 0.88; 95% CI, 0.74 to 1.05; P=0.15) and noncardiovascular (94 [1.0%] vs 121 [1.3%]; HR, 0.77; 95% CI, 0.59 to 1.01; P=0.06) deaths with alirocumab. In a prespecified analysis of 8242 patients eligible for ≥3 years follow-up, alirocumab reduced death (HR, 0.78; 95% CI, 0.65 to 0.94; P=0.01). Patients with nonfatal cardiovascular events were at increased risk for cardiovascular and noncardiovascular deaths (P<0.0001 for the associations). Alirocumab reduced total nonfatal cardiovascular events (P<0.001) and thereby may have attenuated the number of cardiovascular and noncardiovascular deaths. A post hoc analysis found that, compared to patients with lower LDL-C, patients with baseline LDL-C ≥100 mg/dL (2.59 mmol/L) had a greater absolute risk of death and a larger mortality benefit from alirocumab (HR, 0.71; 95% CI, 0.56 to 0.90; Pinteraction=0.007). In the alirocumab group, all-cause death declined wit h achieved LDL-C at 4 months of treatment, to a level of approximately 30 mg/dL (adjusted P=0.017 for linear trend). Conclusions: Alirocumab added to intensive statin therapy has the potential to reduce death after acute coronary syndrome, particularly if treatment is maintained for ≥3 years, if baseline LDL-C is ≥100 mg/dL, or if achieved LDL-C is low. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01663402
Search for pair and single production of new heavy quarks that decay to a Z boson and a third-generation quark in pp collisions at root s=8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdel Khalek S
- Abdinov O
- Aben R
- Abi B
- Abolins M
- Abouzeid Os
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya Bs
- Adamczyk L
- Adams Dl
- Adelman J
- Adomeit S
- Adye T
- Agatonovic-Jovin T
- Aguilar-Saavedra Ja
- Agustoni M
- Ahlen Sp
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson Tpa
- Akimoto G
- Akimov Av
- Alberghi Gl
- Albert J
- Albrand S
- Alconada Verzini Mj
- Aleksa M
- Aleksandrov In
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Alimonti G
- Alio L
- Alison J
- Allbrooke Bmm
- Allison Lj
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- Aloisio A
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- Alpigiani C
- Altheimer A
- Alvarez Gonzalez B
- Alviggi Mg
- Amako K
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- Chernyatin V
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- Kazanin Vf
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- Khovanskiy V
- Khramov E
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- Kiryunin Ae
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- Kiss F
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- Klingenberg R
- Klinger Ja
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- Klok Pf
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- Knoops Ebfg
- Knue A
- Kobayashi D
- Kobayashi T
- Kobel M
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- Kodys P
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- Koletsou I
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- Koperny S
- Kopke L
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- Korcyl K
- Kordas K
- Korn A
- Korol Aa
- Korolkov I
- Korolkova Ev
- Korotkov Va
- Kortner O
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- Kostyukhin Vv
- Kotov Vm
- Kotwal A
- Kourkoumelis C
- Kouskoura V
- Koutsman A
- Kowalewski R
- Kowalski Tz
- Kozanecki W
- Kozhin As
- Kral V
- Kramarenko Va
- Kramberger G
- Krasnopevtsev D
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- Kraus Jk
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- Lampen Cl
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- Lavrijsen W
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- Le Menedeu E
- Lecompte T
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- Leitner R
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- Loginov A
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- Macina D
- Madaffari D
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- Madsen A
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- Maevskiy A
- Magradze E
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- Marroquim F
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- Mashinistov R
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- Mazzaferro L
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- Mc Kee Sp
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- Mccarthy Rl
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- Mcfayden Ja
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- Myska M
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- Papadopoulou Td
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- Piacquadio G
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- Sipica V
- Siragusa G
- Sircar A
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- Publication venue
- Publication date
- 01/01/2014
- Field of study
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