217 research outputs found
Performance of the CMS Cathode Strip Chambers with Cosmic Rays
- Author
- Abadjiev K
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abelev B
- Acosta D
- Acosta JG
- Acosta MV
- Actis O
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adolphi R
- Adzic P
- Afaq MA
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Ahmad M
- Ahmad WH
- Ahmed I
- Ahmed W
- Ahuja S
- Aisa D
- Aisa S
- Akchurin N
- Akgun B
- Akgun U
- Akimenko S
- Akin IV
- Alagoz E
- Alampi G
- Albajar C
- Albayrak EA
- Alberdi J
- Albergo S
- Albert E
- Albrow M
- Alexander J
- Alidra M
- Aliev T
- Allfrey P
- Almeida N
- Altenhofer G
- Altsybeev I
- Alver B
- Alverson G
- Alves GA
- Amaglobeli N
- Amapane N
- Ambroglini F
- Amsler C
- Anagnostou G
- Ananthan B
- Anastassov A
- Andelin D
- Anderson M
- Andrea J
- Andreev V
- Andreev Y
- Anghel IM
- Anguelov T
- Anh T. Vu
- Anisimov A
- Antillon E
- Antipov P
- Antonelli L
- Anttila E
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Apresyan A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arnold B
- Arora S
- Artamonov A
- Asaadi J
- Asghar MI
- Ashby S
- Askew A
- Atac M
- Atramentov O
- Auffray E
- Aurisano A
- Autermann C
- Avery P
- Avetisyan A
- Avila C
- Awan MIM
- Ayan AS
- Ayhan A
- Azhgirey I
- Aziz T
- Azzi P
- Azzurri P
- Baarmand MM
- Babb J
- Babucci E
- Baccaro S
- Bacchetta N
- Bacchi W
- Bachtis M
- Baden D
- Badgett W
- Baechler J
- Baer H
- Baesso P
- Baffioni S
- Bagby L
- Bagliesi G
- Bahk SY
- Bailleux D
- Baillon P
- Bainbridge R
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- Bakken JA
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- Baldin B
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- Banerjee S
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- Bansal S
- Banzuzi K
- Barashko V
- Barbagli G
- Barberis E
- Barbone L
- Barcala JM
- Barcellan L
- Bard R
- Bargassa P
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- Barnett BA
- Barney D
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- Bartalini P
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- Battilana C
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- Belforte S
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- Belotelov I
- Benaglia A
- Bencze G
- Bendavid J
- Bender W
- Benedetti D
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- Benvenuti AC
- Berengueres JOL
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- Besson A
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- Bhatti A
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- Bocci A
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- Bornheim A
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- Cakir I. Turk
- Calderon A
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- Calvo E
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- Camanzi B
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- Campderros JD
- Campi D
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- Capiluppi P
- Caponeri B
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- Carlin R
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- Cartiglia N
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- Cassel D
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- Castello R
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- Cattai A
- Caudron J
- Cavallari F
- Cavallo FR
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- Cebra D
- Cepeda M
- Cerati GB
- Cerci S
- Cerizza G
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- Ceron C
- Cerrada M
- Chabert EC
- Chan M
- Chandra A
- Chang P
- Chang S
- Chang YH
- Chanon N
- Chao Y
- Charaf O
- Charlot C
- Chatelain JP
- Chatrchyan S
- Chatterjee A
- Chauhan S
- Chauvey M
- Checchia P
- Checcucci B
- Chekhovsky V
- Chen EA
- Chen GM
- Chen HS
- Chen J
- Chen KF
- Chen M
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- Cheng TL
- Chertok M
- Chetluru V
- Cheung HWK
- Chien CY
- Chierici R
- Chiochia V
- Chiorboli M
- Chipaux R
- Chiumarulo F
- Chlebana F
- Choi M
- Choi S
- Choi Y
- Chou JP
- Choudhary BC
- Choudhury RK
- Christian G
- Christiansen T
- Chtchipounov L
- Chuang SH
- Chung J
- Chung K
- Chung YS
- Churin I
- Chwalek T
- Cihangir S
- Cimmino A
- Cirino G
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clarida W
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- Cline D
- Cockerill DJA
- Codispoti G
- Colafranceschi S
- Colaleo A
- Cole JE
- Colino N
- Colling D
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- Conetti S
- Contardo D
- Conte E
- Conti E
- Conway J
- Cooper SI
- Cordonnier AM
- Cortabitarte RV
- Cossutti F
- Costa M
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- Coughlan JA
- Cousins R
- Covarelli R
- Cox B
- Cox PT
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- Creanza D
- Cremaldi LM
- Cripps N
- Crotty I
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cuplov V
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- Cuscela G
- Cushman P
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- Cutts D
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- D'Alfonso M
- D'Angelo P
- D'Antone I
- D'Enterria D
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- Dabrowski R
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- Daubie E
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- Di Giovanni GP
- Di Marco E
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- Dias MAF
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- Dimitrov A
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- Dinardo ME
- Dinu N
- Dirkes G
- Dissertori G
- Dittmar M
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- Djordjevic M
- Do Amaral SMS
- Dobrzynski L
- Dobur D
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- Dolgopolov A
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- Dominik W
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- Druzhkin D
- Dubinin M
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- Dumanoglu I
- Dumitrache F
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- Dutta D
- Dutta S
- Dvornikov O
- Dykstra D
- Dyulendarova M
- Dzelalija M
- Eads M
- Eartly DP
- Eckerlin G
- Ecklund KM
- Eckstein D
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- Filozova I
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- Xaplanteris L.
- Xella S.
- Xie S
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- Zabi A
- Zabolotny W
- Zachariadou A
- Zalewski P
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- Zanetti M
- Zang SL
- Zarubin A
- Zatzerklyany A
- Zeidler C
- Zeinali M
- Zeise M
- Zelepoukine S
- Zeuner WD
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- Zhukov V
- Zhukova V
- Ziebarth EB
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2009
- Field of study
The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device
in the CMS endcaps. Their performance has been evaluated using data taken
during a cosmic ray run in fall 2008. Measured noise levels are low, with the
number of noisy channels well below 1%. Coordinate resolution was measured for
all types of chambers, and fall in the range 47 microns to 243 microns. The
efficiencies for local charged track triggers, for hit and for segments
reconstruction were measured, and are above 99%. The timing resolution per
layer is approximately 5 ns
Saturation of an Intra-Gene Pool Linkage Map: Towards a Unified Consensus Linkage Map for Fine Mapping and Synteny Analysis in Common Bean
- Author
- A Frei
- Andrea C. Fernandez
- B Collard
- BK Hougaard
- BN Jackson
- Carlos H. Galeano
- CE Vallejos
- CH Galeano
- CH Galeano
- CL Marino
- E GĂĄitan-Solis
- E Lander
- E Mace
- E Mace
- ET Caixeta
- GC Buso
- GV Caldas
- H Cuevas
- H Liao
- HD Lopez-Marin
- Hyten
- IV Yap
- J Gustafson
- J Salse
- J Schmutz
- J Tohme
- J Wang
- J-M Lacape
- JM CĂłrdoba
- JM CĂłrdoba
- JM Guerra-Sanz
- Jos Vanderleyden
- KA Cichy
- Karen A. Cichy
- L Hanai
- M Blair
- M Blair
- M Blair
- M Blair
- M Krzywinski
- M McConnell
- M Spiller
- Matthew W. Blair
- MCM Grisi
- MJ Bassett
- MW Blair
- MW Blair
- MWF Yaish
- Natalia Franco-Herrera
- P Gepts
- P McClean
- P Stam
- Phillip E. McClean
- R Freyre
- R Remans
- RE Voorrips
- RO Nodari
- S Vezzulli
- SB Cannon
- SE Beebe
- T Close
- T de Campos
- Tongming Yin
- UM Quraishi
- W Muchero
- W Muchero
- WD Beavis
- Y Wu
- Publication venue
- Public Library of Science
- Publication date
- 08/12/2011
- Field of study
Map-based cloning and fine mapping to find genes of interest and marker assisted selection (MAS) requires good genetic maps with reproducible markers. In this study, we saturated the linkage map of the intra-gene pool population of common bean DOR364ĂBAT477 (DB) by evaluating 2,706 molecular markers including SSR, SNP, and gene-based markers. On average the polymorphism rate was 7.7% due to the narrow genetic base between the parents. The DB linkage map consisted of 291 markers with a total map length of 1,788 cM. A consensus map was built using the core mapping populations derived from inter-gene pool crosses: DOR364ĂG19833 (DG) and BAT93ĂJALO EEP558 (BJ). The consensus map consisted of a total of 1,010 markers mapped, with a total map length of 2,041 cM across 11 linkage groups. On average, each linkage group on the consensus map contained 91 markers of which 83% were single copy markers. Finally, a synteny analysis was carried out using our highly saturated consensus maps compared with the soybean pseudo-chromosome assembly. A total of 772 marker sequences were compared with the soybean genome. A total of 44 syntenic blocks were identified. The linkage group Pv6 presented the most diverse pattern of synteny with seven syntenic blocks, and Pv9 showed the most consistent relations with soybean with just two syntenic blocks. Additionally, a co-linear analysis using common bean transcript map information against soybean coding sequences (CDS) revealed the relationship with 787 soybean genes. The common bean consensus map has allowed us to map a larger number of markers, to obtain a more complete coverage of the common bean genome. Our results, combined with synteny relationships provide tools to increase marker density in selected genomic regions to identify closely linked polymorphic markers for indirect selection, fine mapping or for positional cloning
Mitophagy plays a central role in mitochondrial ageing
- Author
- A Ben-Meir
- A Bender
- A Bezawork-Geleta
- A Diot
- A Hansson
- A Johansson
- A Lass
- A Rana
- A Sanz
- A Schiavi
- A Trifunovic
- A Trifunovic
- A Varela-Lopez
- AA Goldberg
- AE Civitarese
- Alan Diot
- AM Aerts
- AM Aerts
- AM Joseph
- AM Nargund
- AM Nargund
- AN Rosario Marinho do
- AR Konopka
- AR Tyrka
- AW Ferree
- AW Linnane
- B Bai
- B Yang
- BA Payne
- BH Ahn
- BJ Blanchard
- C Correia-Melo
- C Giuliani
- C Gong
- C Lopez-Otin
- C Munscher
- C Porter
- C Quan
- CA Chougnet
- CA Koczor
- CD Calloway
- CD Wiley
- CF Bennett
- CH Tengan
- CH Wang
- CK Costa da
- CM Haynes
- CM Haynes
- D Bellizzi
- D Bernhardt
- D Harman
- DA Pulliam
- DC Chan
- DG Murdock
- DJ Baker
- DJ Smiraglia
- DM Skovronsky
- E Bergamini
- E Jing
- E Owusu-Ansah
- E Sidorova-Darmos
- EF Fang
- EI Rugarli
- F Fyhrquist
- F Ko
- F Monickaraj
- F Tian
- G Benedictis De
- G Lopez-Lluch
- G Twig
- GA Cortopassi
- GA Cortopassi
- GJ Tranah
- H Chen
- H Heyn
- H Khraiwesh
- HA Tissenbaum
- HD Osiewacz
- HJ Tritschler
- HJ Weir
- HS Kim
- HY Cohen
- IR Lanza
- J Campisi
- J Clark-Matott
- J Cui
- J Durieux
- J Kaukonen
- J Marin-Garcia
- J Spelbrink
- J Tower
- J Zelenka
- JH Kam
- JJ Wu
- JL Elson
- JL McClay
- JM Carney
- JM Ross
- JN Wolff
- Joanna Poulton
- JP Coppe
- JP Leduc-Gaudet
- K Luce
- K Palikaras
- K Phadwal
- K Phadwal
- K Zarse
- KA Laderman
- Karl Morten
- KC Das
- KD Salpea
- KE Wellen
- KF Petersen
- KJ Ahlqvist
- KJ Krishnan
- KM Jacobs
- L Garcia-Prat
- L Papa
- L Pliss
- L Wrobel
- L Zeng
- L Zhang
- LA Bonsignore
- LC Greaves
- LW Finley
- M Corral-Debrinski
- M Kaeberlein
- M Kaeberlein
- M Ristow
- M Schieber
- M Tsuchiya
- M Ulgherait
- MA Birch-Machin
- MA Goodell
- MC Haigis
- MC Velarde
- MD Hirschey
- ME Goldsworthy
- ML Porto
- MM Monick
- MT Burstein
- MV Ivannikov
- MV Miceli
- N Ban
- N Sondheimer
- N Takeda
- NR Sundaresan
- NS Shenker
- P Cassano
- P Katajisto
- PC Tapia
- PE Coskun
- Q Zhao
- R Gredilla
- R Guantes
- R Guantes
- R Higuchi
- R Lardenoije
- R Muir
- R Naviaux
- R Sreekumar
- R Tao
- R Whitaker
- RA Nixon
- RD Evans
- RD Kelly
- RD Kelly
- RJ Braun
- RM Monaghan
- RS Sohal
- S Ahmed
- S Das
- S Horvath
- S Javadov
- S Melov
- S Minocherhomji
- S Shah
- S Simonetti
- S Someya
- S Takeuchi
- SA Samant
- SH Dai
- SJ Lin
- SJ Lin
- SJ Mitchell
- SL Hebert
- SL Rea
- SM Jazwinski
- SM Jin
- T Sasaki
- T Sekito
- T Wang
- TB Kirkwood
- TJ LaRocca
- TY Kim
- V Romanello
- VS Parikh
- W Haes De
- W Song
- W Yang
- X Li-Harms
- Y Jia
- Y Kanfi
- Y Mikhed
- Y Takihara
- YH Wei
- YY Park
- YY Zhang
- ZY Tam
- ZY Tam
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
The mechanisms underlying ageing have been discussed for decades, and advances in molecular and cell biology of the last three decades have accelerated research in this area. Over this period, it has become clear that mitochondrial function, which plays a major role in many cellular pathways from ATP production to nuclear gene expression and epigenetics alterations, declines with age. The emerging concepts suggest novel mechanisms, involving mtDNA quality, mitochondrial dynamics or mitochondrial quality control. In this review, we discuss the impact of mitochondria in the ageing process, the role of mitochondria in reactive oxygen species production, in nuclear gene expression, the accumulation of mtDNA damage and the importance of mitochondrial dynamics and recycling. Declining mitophagy (mitochondrial quality control) may be an important component of human ageing
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- AbellĂĄn AN
- AbellĂĄn AN
- AbellĂĄn AN
- Abrams ST
- Ackerley C
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- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
- AlcĂĄzar L
- Aldabo-Pallas T
- Aldana NN
- Aldecoa C
- AlegrĂa L
- Alejandro R
- Alejo GC
- Alejos RM
- Alexandrova E
- Algarte R
- Algarte R
- Algieri I
- Algora-Weber A
- Alhamdi Y
- Aliaga FA
- Aliberti S
- Alkan A
- Almudena PM
- Almudevar PM
- Almudevar PM
- AlmudĂŠvar PM
- AltÄąntas ND
- Alvarez J
- Alves SC
- Alzola LM
- Amargianitakis V
- Amaro R
- Amato MB
- Ambler M
- Amerongen MP
- Amininejad T
- Amor LL
- Amorim V
- Anand RK
- Andersen LW
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- Andrade AH
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- ARIAM registry of adult cardiac surgery
- ARIAM-ANDALUCIA
- Arias CC
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- Artiguenave M
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- ENVIN-HELICS Study Group
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- GETGAG Working Group
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- IPREA Study Group
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- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
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- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
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- SabeÄźĹikovs O
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- Saha T
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- Sawamura A
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- Scales DC
- Scanziani E
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- Schaller SJ
- Schlaepfer P
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- Schmid RM
- Schmidt M
- Schneider AG
- Schoenenberger JA
- Schortgen F
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- Sciurti R
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- Seldon T
- SellĂŠs MD
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- St Georgeâs University of London
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- Stretti F
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- Stubbs C
- Stubbs C
- Student Research Committee - Shiraz University of Medical Sciences
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- Suchomel P
- Suh GJ
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- SĂĄnchez MJ
- SĂĄnchez PC
- SĂĄnchez PC
- SĂĄnchez-Elvira LA
- Tabatabaei HR
- Tabei SH
- Taccone F
- Taccone FS
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- Tokyo Womens Medical University
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- van Putten MJ
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- van Wijk A
- Vandijck D
- Vaneker I
- Vanhuyse F
- Vaporidi K
- Vaquerizo C
- Varas GM
- Varas JL
- Varea MM
- Vargiolu A
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- Vigne C
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- Villard I
- Villarreal E
- Villarreal E
- Vincent B
- Vincent JL
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- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vinje LJ
- Vinsonneau C
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- Vittone F
- Vogelaers D
- Voiriot G
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- Volta CA
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- Vondrakova D
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- Waldauf P
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- Welters I
- Wetz A
- Weyer CM
- White C
- Wiesner O
- Wijayatilake DS
- Wildenberg L
- Wilks M
- Wilson ME
- WIND study group
- WIND study group
- WIND study group
- Winder-Rhodes S
- Witter T
- Wolf M
- Wolff M
- Wong Y
- Wood B
- Wood CA
- Wood D
- Wood M
- Wray J
- Xie Z
- Xini A
- Xini A
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- Xu M
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- Yaguchi A
- Yaguchi A
- Yamaguchi O
- Yamaguchi O
- Yamaguchi Y
- Yamaguchi Y
- Yamamoto H
- Yamamoto N
- Yaman G
- Yamashita K
- Yamazaki A
- Yan WW
- Yan WW
- Yang JH
- Yang JS
- Yang YL
- Yasuda H
- Yatabe T
- Yebenes JC
- Yeh YC
- Yemets H
- Yergaliyeva A
- YÄąlmaz G
- Yilmazer F
- Yodice P
- Yokoyama M
- Yonis H
- Yonis H
- Yonis H
- Yoon SZ
- Yoruk F
- Yoshida K
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
- You KM
- Youn AM
- Young A
- Yu KM
- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
- Zahorec M
- Zaien I
- Zakynthinos S
- Zanello M
- Zani D
- Zarantonello F
- Zayas B
- Zepeda EM
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- Zwaag J
- Zýkovå I
- Ălvarez JT
- Ălvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
CMS Data Processing Workflows during an Extended Cosmic Ray Run
- Author
- Abadjiev K
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abelev B
- Acosta D
- Acosta JG
- Acosta MV
- Actis O
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adolphi R
- Adzic P
- Afaq MA
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Ahmad M
- Ahmad WH
- Ahmed I
- Ahmed W
- Ahuja S
- Aisa D
- Aisa S
- Akchurin N
- Akgun B
- Akgun U
- Akimenko S
- Akin IV
- Alagoz E
- Alampi G
- Albajar C
- Albayrak EA
- Alberdi J
- Albergo S
- Albert E
- Albrow M
- Alexander J
- Alidra M
- Aliev T
- Allfrey P
- Almeida N
- Altenhofer G
- Altsybeev I
- Alver B
- Alverson G
- Alves GA
- Amaglobeli N
- Amapane N
- Ambroglini F
- Amsler C
- Anagnostou G
- Ananthan B
- Anastassov A
- Andelin D
- Anderson M
- Andrea J
- Andreev V
- Andreev Y
- Anghel IM
- Anguelov T
- Anisimov A
- Antillon E
- Antipov P
- Antonelli L
- Anttila E
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Apresyan A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arnold B
- Arora S
- Artamonov A
- Asaadi J
- Asghar MI
- Ashby S
- Askew A
- Atac M
- Atramentov O
- Auffray E
- Aurisano A
- Autermann C
- Avery P
- Avetisyan A
- Avila C
- Awan MIM
- Ayan AS
- Ayhan A
- Azhgirey I
- Aziz T
- Azzi P
- Azzurri P
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- Wyslouch B
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- Zachariadou A
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- Publication venue
- INSTITUTE OF PHYSICS PUBLISHING
- Publication date
- 01/01/2009
- Field of study
Peer reviewe
Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial
- Author
- Abbas J
- Abbate A
- Abdullakutty J
- Abhyanakar AD
- Aboyans V
- Abrantes JAM
- Abu-Fadel M
- Acevedo M
- Adamkova V
- Adhyapak S
- Agarwal H
- Aggarwal R
- Aggarwal RK
- Aguirre A
- Ahmed H
- Ahremark U
- Ahuad Guerrero RA
- Aidar Ayoub JC
- Airaksinen JK
- Aitken D
- Akatova E
- Akhter F
- Ako J
- Akright L
- Akyea-Djamson A
- Al Joundi T
- Al-Windy NYY
- Alan D
- Alcocer Gamba MA
- Alexander JH
- Alexander K
- Alexandru TM
- Alings M
- Alonso Martin JJ
- Alvarisqueta AF
- Alves De Lima AE
- Amarasekera S
- Amarasena N
- Amir O
- Amlani M
- Amosova E
- Amuchastegui M
- Andersen K
- Andersen R
- Anderson J
- Ando K
- Angel Hominal M
- Annam S
- Anscombe R
- Apostolovic SR
- Appel K-F
- Arandjelovic A
- Araneda G
- Arango Benecke JL
- Arbel Y
- Arif I
- Armaganijan L
- Arroyo JAC
- Arstall MA
- Asanin MR
- Atar S
- Athyros V
- Auguadro C
- Ayala CAC
- Aylward PE
- Azizad MM
- Bagai A
- Bagriy A
- Bahit MC
- Bai F
- Balaguer Recena J
- Baldari D
- Balinovac J
- Ball E
- Bang LE
- Banuru S
- Barakovic F
- Baranov E
- Baranova E
- Barbarash OL
- Barbato E
- Barna OM
- Barone-Rochette G
- Barr C
- Barrucco R
- Bartels GL
- Bashir R
- Basson MMDV
- Bastos JM
- Bata I
- Batushkin V
- Bayat J
- Bayram Llamas EA
- Bayron C
- Beauloye C
- Bednarski J
- Behrens S
- Belhassane A
- Benedicto A
- Bengus CM
- Benov HO
- Berger R
- Berglund S
- Berk M
- Berland J
- Berli MA
- Berlowitz M
- Berman B
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- Bhagwat R
- Bhansali P
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- Birchem J
- Bittner VA
- Blicharski T
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- Blumberg EDS
- Boccara F
- Bodanese LC
- Bodi Peris V
- Boecker D
- Bojovski S
- Bokarev I
- Bokern MJJA
- Bonfanti AJC
- Bono JOE
- Bordonava AP
- Borse R
- Bortnick A
- Bos RJ
- Botas Rodriguez J
- Botelho A
- Botelho RV
- Botia DCL
- Bottcher M
- Bourgeois R
- Brabham D
- Braganza D
- Braun-Dullaeus R
- Breedveld RW
- Brennan JM
- Brodison A
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- Yang X
- Yang X
- Yao Z
- Yazdani S
- Yerra SK
- Yin W-H
- Yong H
- Yoon JH
- Younis L
- Yu Y
- Yuan Z
- Yusoff K
- Zahger D
- Zaidman CJ
- Zainea M
- Zaman A
- Zeiher AM
- Zhang W
- Zhang X
- Zhang Z
- Zhao X
- Zheng Y
- Zheng Z
- Zhou Y
- Zhu H
- Zirlik A
- Zizka J
- Zong W
- Zrazhevsky K
- Zuniga JDH
- Zurakowski A
- Zuran I
- Zweiker R
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2019
- Field of study
Aimsâ The third Universal Definition of Myocardial Infarction (MI) Task Force classified MIs into five types: Type 1, spontaneous; Type 2, related to oxygen supply/demand imbalance; Type 3, fatal without ascertainment of cardiac biomarkers; Type 4, related to percutaneous coronary intervention; and Type 5, related to coronary artery bypass surgery. Low-density lipoprotein cholesterol (LDL-C) reduction with statins and proprotein convertase subtilisinâkexin Type 9 (PCSK9) inhibitors reduces risk of MI, but less is known about effects on types of MI. ODYSSEY OUTCOMES compared the PCSK9 inhibitor alirocumab with placebo in 18 924 patients with recent acute coronary syndrome (ACS) and elevated LDL-C (âĽ1.8âmmol/L) despite intensive statin therapy. In a pre-specified analysis, we assessed the effects of alirocumab on types of MI. Methods and resultsâ Median follow-up was 2.8âyears. Myocardial infarction types were prospectively adjudicated and classified. Of 1860 total MIs, 1223 (65.8%) were adjudicated as Type 1, 386 (20.8%) as Type 2, and 244 (13.1%) as Type 4. Few events were Type 3 (nâ=â2) or Type 5 (nâ=â5). Alirocumab reduced first MIs [hazard ratio (HR) 0.85, 95% confidence interval (CI) 0.77â0.95; Pâ=â0.003], with reductions in both Type 1 (HR 0.87, 95% CI 0.77â0.99; Pâ=â0.032) and Type 2 (0.77, 0.61â0.97; Pâ=â0.025), but not Type 4 MI. Conclusionâ After ACS, alirocumab added to intensive statin therapy favourably impacted on Type 1 and 2 MIs. The data indicate for the first time that a lipid-lowering therapy can attenuate the risk of Type 2 MI. Low-density lipoprotein cholesterol reduction below levels achievable with statins is an effective preventive strategy for both MI types.For complete list of authors see http://dx.doi.org/10.1093/eurheartj/ehz299</p
Aligning the CMS Muon Chambers with the Muon Alignment System during an Extended Cosmic Ray Run
- Author
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- Publication venue
- Publication date
- 01/01/2009
- Field of study
Peer reviewe
Lawson criterion for ignition exceeded in an inertial fusion experiment
- Author
- Abu-Shawareb H
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- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 06/07/2022
- Field of study
For more than half a century, researchers around the world have been engaged in attempts to achieve fusion ignition as a proof of principle of various fusion concepts. Following the Lawson criterion, an ignited plasma is one where the fusion heating power is high enough to overcome all the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop with rapidly increasing temperature. In inertially confined fusion, ignition is a state where the fusion plasma can begin "burn propagation" into surrounding cold fuel, enabling the possibility of high energy gain. While "scientific breakeven" (i.e., unity target gain) has not yet been achieved (here target gain is 0.72, 1.37Â MJ of fusion for 1.92Â MJ of laser energy), this Letter reports the first controlled fusion experiment, using laser indirect drive, on the National Ignition Facility to produce capsule gain (here 5.8) and reach ignition by nine different formulations of the Lawson criterion
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
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- Mohamed M
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- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
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- Author
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- Publication venue
- 'IOP Publishing'
- Publication date
- 26/11/2009
- Field of study
This is the Pre-print version of the Article. The official published version of the paper can be accessed from the link below - Copyright @ 2010 IOPThe CMS High-Level Trigger (HLT) is responsible for ensuring that data samples with potentially interesting events are recorded with high efficiency and good quality. This paper gives an overview of the HLT and focuses on its commissioning using cosmic rays. The selection of triggers that were deployed is presented and the online grouping of triggered events into streams and primary datasets is discussed. Tools for online and offline data quality monitoring for the HLT are described, and the operational performance of the muon HLT algorithms is reviewed. The average time taken for the HLT selection and its dependence on detector and operating conditions are presented. The HLT performed reliably and helped provide a large dataset. This dataset has proven to be invaluable for understanding the performance of the trigger and the CMS experiment as a whole.This work is supported by FMSR (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ,
and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS
(Colombia); MSES (Croatia); RPF (Cyprus); Academy of Sciences and NICPB (Estonia);
Academy of Finland, ME, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); PAEC (Pakistan); SCSR (Poland); FCT (Portugal); JINR
(Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MST and MAE (Russia); MSTDS (Serbia); MICINN and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)
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