Landslide and mass movement processes and their distribution in Longdendale Valley and Glossop District (sheet 86)

This report describes the geographical extent of the landslides and the mass movement mechanisms responsible for landslide deposits in the Longdendale valley. In addition an overview of the slope processes in the Glossop district is also presented

Highlights from the NA60 experiment

The NA60 experiment is a fixed-target experiment at the CERN SPS. It has measured the dimuon yield in Indium--Indium collisions with an In beam of 158 AGeV/c and in p-A collisions with a proton beam of 400 and 158 AGeV/c. The results allow to address three important physics topics, namely the study of the rho spectral function in nuclear collisions, the clarification of the origin of the dimuon excess measured by NA50 in the intermediate mass range, and the J/psi suppression pattern in a collision system different from Pb-Pb. An overview of these results will be given in this paper

NA60 results on the rho spectral function in In-In collisions

The NA60 experiment at the CERN SPS has studied low-mass muon pairs in 158 AGeV In-In collisions. A strong excess of pairs is observed above the yield expected from neutral meson decays. After subtraction of the decay sources, the shape of the resulting mass spectrum is largely consistent with a dominant contribution from pi+pi- -> rho -> mu+mu- annihilation. The associated rho spectral function exhibits considerable broadening, but essentially no shift in mass. The acceptance-corrected pT spectra have a shape atypical for radial flow. They also significantly depend on mass, pointing to different sources in different mass regions. Both mass and pT spectra are compared to recent theoretical predictions.Comment: Prepared for International Conference on Hard and Electromagnetic Probes of High-Energy Nuclear Collisions (Hard Probes 2006), Asilomar, Pacific Grove, California, 9-16 Jun 200

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.

TCF3-HLF-positive acute lymphoblastic leukemia (ALL) is currently incurable. Using an integrated approach, we uncovered distinct mutation, gene expression and drug response profiles in TCF3-HLF-positive and treatment-responsive TCF3-PBX1-positive ALL. We identified recurrent intragenic deletions of PAX5 or VPREB1 in constellation with the fusion of TCF3 and HLF. Moreover somatic mutations in the non-translocated allele of TCF3 and a reduction of PAX5 gene dosage in TCF3-HLF ALL suggest cooperation within a restricted genetic context. The enrichment for stem cell and myeloid features in the TCF3-HLF signature may reflect reprogramming by TCF3-HLF of a lymphoid-committed cell of origin toward a hybrid, drug-resistant hematopoietic state. Drug response profiling of matched patient-derived xenografts revealed a distinct profile for TCF3-HLF ALL with resistance to conventional chemotherapeutics but sensitivity to glucocorticoids, anthracyclines and agents in clinical development. Striking on-target sensitivity was achieved with the BCL2-specific inhibitor venetoclax (ABT-199). This integrated approach thus provides alternative treatment options for this deadly disease

Quantum dots coordinated with conjugated organic ligands: new nanomaterials with novel photophysics

CdSe quantum dots functionalized with oligo-(phenylene vinylene) (OPV) ligands (CdSe-OPV nanostructures) represent a new class of composite nanomaterials with significantly modified photophysics relative to bulk blends or isolated components. Single-molecule spectroscopy on these species have revealed novel photophysics such as enhanced energy transfer, spectral stability, and strongly modified excited state lifetimes and blinking statistics. Here, we review the role of ligands in quantum dot applications and summarize some of our recent efforts probing energy and charge transfer in hybrid CdSe-OPV composite nanostructures

Combination of searches for Higgs boson pairs in pp collisions at \sqrts = 13 TeV with the ATLAS detector

This letter presents a combination of searches for Higgs boson pair production using up to 36.1 fb(-1) of proton-proton collision data at a centre-of-mass energy root s = 13 TeV recorded with the ATLAS detector at the LHC. The combination is performed using six analyses searching for Higgs boson pairs decaying into the b (b) over barb (b) over bar, b (b) over barW(+)W(-), b (b) over bar tau(+)tau(-), W+W-W+W-, b (b) over bar gamma gamma and W+W-gamma gamma final states. Results are presented for non-resonant and resonant Higgs boson pair production modes. No statistically significant excess in data above the Standard Model predictions is found. The combined observed (expected) limit at 95% confidence level on the non-resonant Higgs boson pair production cross-section is 6.9 (10) times the predicted Standard Model cross-section. Limits are also set on the ratio (kappa(lambda)) of the Higgs boson self-coupling to its Standard Model value. This ratio is constrained at 95% confidence level in observation (expectation) to -5.0 &lt; kappa(lambda) &lt; 12.0 (-5.8 &lt; kappa(lambda) &lt; 12.0). In addition, limits are set on the production of narrow scalar resonances and spin-2 Kaluza-Klein Randall-Sundrum gravitons. Exclusion regions are also provided in the parameter space of the habemus Minimal Supersymmetric Standard Model and the Electroweak Singlet Model. For complete list of authors see http://dx.doi.org/10.1016/j.physletb.2019.135103</p

`Football Remembers':The Collective Memory of Football in the Spectacle of British Military Commemoration

This article examines two major rituals of contemporary national life in the UK: association football and military commemoration. It explores the ways in which remembering is enacted and performed within UK football and how these processes are related to issues of power, agency and identity in Britain today. Employing the concepts of collective memory and spectacle, this article argues that ‘memory entrepreneurs’ have sought to embed football as ‘site of memory’ in the performance of military commemoration. It concludes that this has contributed to the transformation of military commemoration, from a ritual that is observed to a spectacle that is consumed. This paper thus contributes to emergent debates on the militarization of civilian space, the shifting nature of civil–military relations in the twenty-first century, and the role of military remembrance in the reproduction of Britishness

First Sagittarius A* Event Horizon Telescope results. I. The shadow of the supermassive black hole in the center of the Milky Way

Galaxie

First Sagittarius A* event horizon telescope results. II. EHT and multiwavelength observations, data processing, and calibration

Instrumentatio