On the comparison of analog and digital SiPM readout in terms of expected timing performance

AbstractIn time of flight positron emission tomography (TOF-PET) and in particular for the EndoTOFPET-US Project (Frisch, 2013 [1]), and other applications for high energy physics, the multi-digital silicon photomultiplier (MD-SiPM) was recently proposed (Mandai and Charbon, 2012 [2]), in which the time of every single photoelectron is being recorded. If such a photodetector is coupled to a scintillator, the largest and most accurate timing information can be extracted from the cascade of the scintillation photons, and the most probable time of positron emission determined. The readout concept of the MD-SiPM is very different from that of the analog SiPM, where the individual photoelectrons are merely summed up and the output signal fed into the readout electronics. We have developed a comprehensive Monte Carlo (MC) simulation tool that describes the timing properties of the photodetector and electronics, the scintillation properties of the crystal and the light transfer within the crystal. In previous studies we have compared MC simulations with coincidence time resolution (CTR) measurements and found good agreement within less than 10% for crystals of different lengths (from 3mm to 20mm) coupled to SiPMs from Hamamatsu. In this work we will use the developed MC tool to directly compare the highest possible time resolution for both the analog and digital readout of SiPMs with different scintillator lengths. The presented studies reveal that the analog readout of SiPMs with microcell signal pile-up and leading edge discrimination can lead to nearly the same time resolution as compared to the maximum likelihood time estimation applied to MD-SiPMs. Consequently there is no real preference for either a digital or analog SiPM for the sake of achieving highest time resolution. However, the best CTR in the analog SiPM is observed for a rather small range of optimal threshold values, whereas the MD-SiPM provides stable CTR after roughly 20 registered photoelectron timestamps in the time estimator

Ultrafast emission from colloidal nanocrystals under pulsed X-ray excitation

Fast timing has emerged as a critical requirement for radiation detection in medical and high energy physics, motivating the search for scintillator materials with high light yield and fast time response. However, light emission rates from conventional scintillation mechanisms fundamentally limit the achievable time resolution, which is presently at least one order of magnitude slower than required for next-generation detectors. One solution to this challenge is to generate an intense prompt signal in response to ionizing radiation. In this paper, we present colloidal semiconductor nanocrystals (NCs) as promising prompt photon sources. We investigate two classes of NCs: two-dimensional CdSe nanoplatelets (NPLs) and spherical CdSe/CdS core/giant shell quantum dots (GS QDs). We demonstrate that the emission rates of these NCs under pulsed X-ray excitation are much faster than traditional mechanisms in bulk scintillators, i.e. 5d-4f transitions. CdSe NPLs have a sub-100 ps effective decay time of 77 ps and CdSe/CdS GS QDs exhibit a sub-ns value of 849 ps. Further, the respective CdSe NPL and CdSe/CdS GS QD X-ray excited photoluminescence have the emission characteristics of excitons (X) and multiexcitons (MX), with the MXs providing additional prospects for fast timing with substantially shorter lifetimes

A Comprehensive & Systematic Study of Coincidence Time Resolution and Light Yield Using Scintillators of Different Size and Wrapping

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Measurement of isolated photon production in pp and PbPb collisions at sqrt(sNN) = 2.76 TeV

Isolated photon production is measured in proton-proton and lead-lead collisions at nucleon-nucleon centre-of-mass energies of 2.76 TeV in the pseudorapidity range |eta|<1.44 and transverse energies ET between 20 and 80 GeV with the CMS detector at the LHC. The measured ET spectra are found to be in good agreement with next-to-leading-order perturbative QCD predictions. The ratio of PbPb to pp isolated photon ET-differential yields, scaled by the number of incoherent nucleon-nucleon collisions, is consistent with unity for all PbPb reaction centralities.Comment: Submitted to Physics Letters

Characterization of mercury bioremediation by transgenic bacteria expressing metallothionein and polyphosphate kinase

<p>Abstract</p> <p>Background</p> <p>The use of transgenic bacteria has been proposed as a suitable alternative for mercury remediation. Ideally, mercury would be sequestered by metal-scavenging agents inside transgenic bacteria for subsequent retrieval. So far, this approach has produced limited protection and accumulation. We report here the development of a transgenic system that effectively expresses metallothionein (<it>mt-1</it>) and polyphosphate kinase (<it>ppk</it>) genes in bacteria in order to provide high mercury resistance and accumulation.</p> <p>Results</p> <p>In this study, bacterial transformation with transcriptional and translational enhanced vectors designed for the expression of metallothionein and polyphosphate kinase provided high transgene transcript levels independent of the gene being expressed. Expression of polyphosphate kinase and metallothionein in transgenic bacteria provided high resistance to mercury, up to 80 μM and 120 μM, respectively. Here we show for the first time that metallothionein can be efficiently expressed in bacteria without being fused to a carrier protein to enhance mercury bioremediation. Cold vapor atomic absorption spectrometry analyzes revealed that the <it>mt-1 </it>transgenic bacteria accumulated up to 100.2 ± 17.6 μM of mercury from media containing 120 μM Hg. The extent of mercury remediation was such that the contaminated media remediated by the <it>mt-1 </it>transgenic bacteria supported the growth of untransformed bacteria. Cell aggregation, precipitation and color changes were visually observed in <it>mt-1 </it>and <it>ppk </it>transgenic bacteria when these cells were grown in high mercury concentrations.</p> <p>Conclusion</p> <p>The transgenic bacterial system described in this study presents a viable technology for mercury bioremediation from liquid matrices because it provides high mercury resistance and accumulation while inhibiting elemental mercury volatilization. This is the first report that shows that metallothionein expression provides mercury resistance and accumulation in recombinant bacteria. The high accumulation of mercury in the transgenic cells could present the possibility of retrieving the accumulated mercury for further industrial applications.</p

Search for top squark pair production in pp collisions at root s=13 TeV using single lepton events

Peer reviewe

Search for new physics with dijet angular distributions in proton-proton collisions at root S = 13 TeV

Peer reviewe

Observation of Charge-Dependent Azimuthal Correlations in p-Pb Collisions and Its Implication for the Search for the Chiral Magnetic Effect

Peer reviewe

Search for narrow resonances in dilepton mass spectra in proton-proton collisions at root s=13 TeV and combination with 8 TeV data

Peer reviewe