3,974 research outputs found
Baitfish: Feeds and feeding practices
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Rotation, magnetism, and metallicity of M dwarf systems
Close M-dwarf binaries and higher multiples allow the investigation of
rotational evolution and mean magnetic flux unbiased from scatter in
inclination angle and age since the orientation of the spin axis of the
components is most likely parallel and the individual systems are coeval.
Systems composed of an early (M0.0 -- M4.0) and a late (M4.0 -- M8.0) type
component offer the possibility to study differences in rotation and magnetism
between partially and fully convective stars. We have selected 10 of the
closest dM systems to determine the rotation velocities and the mean magnetic
field strengths based on spectroscopic analysis of FeH lines of Wing-Ford
transitions at 1 m observed with VLT/CRIRES. We also studied the quality
of our spectroscopic model regarding atmospheric parameters including
metallicity. A modified version of the Molecular Zeeman Library (MZL) was used
to compute Land\'e g-factors for FeH lines. Magnetic spectral synthesis was
performed with the Synmast code. We confirmed previously reported findings that
less massive M-dwarfs are braked less effectively than objects of earlier
types. Strong surface magnetic fields were detected in primaries of four
systems (GJ 852, GJ 234, LP 717-36, GJ 3322), and in the secondary of the
triple system GJ 852. We also confirm strong 2 kG magnetic field in the primary
of the triple system GJ 2005. No fields could be accurately determined in
rapidly rotating stars with \vsini>10 \kms. For slow and moderately rotating
stars we find the surface magnetic field strength to increase with the
rotational velocity \vsini which is consistent with other results from
studying field stars.Comment: Accepted by MNRAS, 10 pages, 4 figures, 4 table
Population-Level Benefits from Providing Effective HIV Prevention Means to Pregnant Women in High Prevalence Settings
Background:HIV prevalence among pregnant women in Southern Africa is extremely high. Epidemiological studies suggest that pregnancy increases the risk of HIV sexual acquisition and that HIV infections acquired during pregnancy carry higher risk of mother-to-child transmission (MTCT). We analyze the potential benefits from extending the availability of effective microbicide to pregnant women (in addition to non-pregnant women) in a wide-scale intervention.Methods and Findings:A transmission dynamic model was designed to assess the impact of microbicide use in high HIV prevalence settings and to estimate proportions of new HIV infections, infections acquired during pregnancy, and MTCT prevented over 10 years. Our analysis suggests that consistent use of microbicide with 70% efficacy by 60% of non-pregnant women may prevent approximately 40% and 15% of new infections in women and men respectively over 10 years, assuming no additional increase in HIV risk to either partner during pregnancy (RRHIV/preg = 1). It may also prevent 8-15% MTCT depending on the increase in MTCT risk when HIV is acquired during pregnancy compared to before pregnancy (RRMTCT/preg). Extending the microbicides use during pregnancy may improve the effectiveness of the intervention by 10% (RRHIV/preg = 1) to 25% (RRHIV/preg = 2) and reduce the number of HIV infections acquired during pregnancy by 40% to 70% in different scenarios. It may add between 6% (RRHIV/preg = 1, RRMTCT/preg = 1) and 25% (RRHIV/preg = 2, RRMTCT/preg = 4) to the reduction in the residual MTCT.Conclusion:Providing safe and effective microbicide to pregnant women in the context of wide-scale interventions would be desirable as it would increase the effectiveness of the intervention and significantly reduce the number of HIV infections acquired during pregnancy. The projected benefits from covering pregnant women by the HIV prevention programs is more substantial in communities in which the sexual risk during pregnancy is elevated. © 2013 Dimitrov et al
Inherited biotic protection in a Neotropical pioneer plant
Chelonanthus alatus is a bat-pollinated, pioneer Gentianaceae that clusters in patches where still-standing, dried-out stems are interspersed among live individuals. Flowers bear circum-floral nectaries (CFNs) that are attractive to ants, and seed dispersal is both barochorous and anemochorous. Although, in this study, live individuals never sheltered ant colonies, dried-out hollow stems - that can remain standing for 2 years - did. Workers from species nesting in dried-out stems as well as from ground-nesting species exploited the CFNs of live C. alatus individuals in the same patches during the daytime, but were absent at night (when bat pollination occurs) on 60.5% of the plants. By visiting the CFNs, the ants indirectly protect the flowers - but not the plant foliage - from herbivorous insects. We show that this protection is provided mostly by species nesting in dried-out stems, predominantly Pseudomyrmex gracilis. That dried-out stems remain standing for years and are regularly replaced results in an opportunistic, but stable association where colonies are sheltered by one generation of dead C. alatus while the live individuals nearby, belonging to the next generation, provide them with nectar; in turn, the ants protect their flowers from herbivores. We suggest that the investment in wood by C. alatus individuals permitting stillstanding, dried-out stems to shelter ant colonies constitutes an extended phenotype because foraging workers protect the flowers of live individuals in the same patch. Also, through this process these dried-out stems indirectly favor the reproduction (and so the fitness) of the next generation including both their own offspring and that of their siblings, alladding up to a potential case of inclusive fitness in plants
Net survival of perinatally and postnatally HIV-infected children: a pooled analysis of individual data from sub-Saharan Africa
Background Previously, HIV epidemic models have used a double Weibull curve to represent high initial and late mortality of HIV-infected children, without distinguishing timing of infection (peri- or post-natally). With more data on timing of infection, which may be associated with disease progression, a separate representation of children infected early and late was proposed. Methods Paediatric survival post-HIV infection without anti-retroviral treatment was calculated using pooled data from 12 studies with known timing of HIV infection. Children were grouped into perinatally or post-natally infected. Net mortality was calculated using cause-deleted life tables to give survival as if HIV was the only competing cause of death. To extend the curve beyond the available data, children surviving beyond 2.5 years post infection were assumed to have the same survival as young adults. Double Weibull curves were fitted to both extended survival curves to represent survival of children infected perinatally or through breastfeeding. Results Those children infected perinatally had a much higher risk of dying than those infected through breastfeeding, even allowing for background mortality. The final-fitted double Weibull curves gave 75% survival at 5 months after infection for perinatally infected, and 1.1 years for post-natally infected children. An estimated 25% of the early infected children would still be alive at 10.6 years compared with 16.9 years for those infected through breastfeeding. Conclusions The increase in available data has enabled separation of child mortality patterns by timing of infection allowing improvement and more flexibility in modelling of paediatric HIV infection and surviva
Kepler observations of variability in B-type stars
The analysis of the light curves of 48 B-type stars observed by Kepler is
presented. Among these are 15 pulsating stars, all of which show low
frequencies characteristic of SPB stars. Seven of these stars also show a few
weak, isolated high frequencies and they could be considered as SPB/beta Cep
hybrids. In all cases the frequency spectra are quite different from what is
seen from ground-based observations. We suggest that this is because most of
the low frequencies are modes of high degree which are predicted to be unstable
in models of mid-B stars. We find that there are non-pulsating stars within the
beta Cep and SPB instability strips. Apart from the pulsating stars, we can
identify stars with frequency groupings similar to what is seen in Be stars but
which are not Be stars. The origin of the groupings is not clear, but may be
related to rotation. We find periodic variations in other stars which we
attribute to proximity effects in binary systems or possibly rotational
modulation. We find no evidence for pulsating stars between the cool edge of
the SPB and the hot edge of the delta Sct instability strips. None of the stars
show the broad features which can be attributed to stochastically-excited modes
as recently proposed. Among our sample of B stars are two chemically peculiar
stars, one of which is a HgMn star showing rotational modulation in the light
curve.Comment: 19 pages, 11 figures, 4 table
Oxygen Abundances in Nearby Stars. Clues to the formation and evolution of the Galactic disk
The abundances of iron and oxygen are homogeneously determined in a sample of
523 nearby (d<150 pc) FGK disk and halo stars with metallicities in the range
-1.5<[Fe/H]<0.5. The oxygen abundances were inferred from a restricted non-LTE
analysis of the 777 nm O I triplet. We use the stellar kinematics to compute
the probabilities of our sample stars to be members of the thin disk, thick
disk, or halo of the Galaxy. We find that the majority of the
kinematically-selected thick-disk stars show larger [O/Fe] ratios compared to
thin-disk stars. A close examination of this pattern for disk stars with
ambiguous probabilities shows that an intermediate population with properties
between those of the thin and thick disks does not exist. Excluding the stars
with unusual kinematics, we find that thick-disk stars show slowly decreasing
[O/Fe] ratios from about 0.5 to 0.4 in the -0.8<[Fe/H]<-0.3 range. Using a
simple model for the chemical evolution of the thick disk we show that this
trend results directly from the metallicity dependence of the Type II supernova
yields. At [Fe/H]>-0.3, we find no obvious indication of a sudden decrease
(i.e., a 'knee') in the [O/Fe] vs. [Fe/H] pattern of thick-disk stars that
would connect the thick and thin disk trends at a high metallicity. We conclude
that Type Ia supernovae (SN Ia) did not contribute significantly to the
chemical enrichment of the thick disk. [Abridged]Comment: A&A, in pres
Immunomodulatory factors in cervicovaginal secretions from pregnant and non-pregnant women: A cross-sectional study
<p>Abstract</p> <p>Background</p> <p>Pregnant women are at an increased risk for HIV infection due to unknown biological causes. Given the strong effect of sex-hormones on the expression of immunomuodulatory factors, the central role of mucosal immunity in HIV pathogenesis and the lack of previous studies, we here tested for differences in immunomuodulatory factors in cervico-vaginal secretions between pregnant and non-pregnant women.</p> <p>Methods</p> <p>We compared concentrations of 39 immunomodulatory factors in cervicovaginal lavages (CVL) from 21 pregnant women to those of 24 non-pregnant healthy women from the US. We used Bonferroni correction to correct for multiple testing and linear regression modeling to adjust for possible confounding by plasma cytokine concentration, cervical ectopy, total protein concentration, and other possible confounders. Cervical ectopy was determined by planimetry. Concentration of immunomodulatory factors were measured by a multiplex assay, protein concentration by the Bradford Method.</p> <p>Results</p> <p>Twenty six (66%) of the 39 measured immunomodulatory factors were detectable in at least half of the CVL samples included in the study. Pregnant women had threefold lower CVL concentration of CCL22 (geometric mean: 29.6 pg/ml versus 89.7 pg/ml, p = 0.0011) than non-pregnant women. CVL CCL22 concentration additionally correlated negatively with gestational age (Spearman correlation coefficient [R<sub>S</sub>]: -0.49, p = 0.0006). These associations remained significant when corrected for multiple testing.</p> <p>CCL22 concentration in CVL was positively correlated with age and negatively correlated with time since last coitus and the size of cervical ectopy. However, none of these associations could explain the difference of CCL22 concentration between pregnant and non-pregnant women in this study, which remained significant in adjusted analysis.</p> <p>Conclusions</p> <p>In this study population, pregnancy is associated with reduced concentrations of CCL22 in cervicovaginal secretions. The role of CCL22 on HIV transmission should now be investigated in prospective studies.</p
Astrophysically Triggered Searches for Gravitational Waves: Status and Prospects
In gravitational-wave detection, special emphasis is put onto searches that
focus on cosmic events detected by other types of astrophysical observatories.
The astrophysical triggers, e.g. from gamma-ray and X-ray satellites, optical
telescopes and neutrino observatories, provide a trigger time for analyzing
gravitational wave data coincident with the event. In certain cases the
expected frequency range, source energetics, directional and progenitor
information is also available. Beyond allowing the recognition of gravitational
waveforms with amplitudes closer to the noise floor of the detector, these
triggered searches should also lead to rich science results even before the
onset of Advanced LIGO. In this paper we provide a broad review of LIGO's
astrophysically triggered searches and the sources they target
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