Resultados en recambios de cotilo mediante la técnica de Sloof: nuestra experiencia

Objetivos: osteolisis es un importante problema para el cirujano en los recambios de cotilo. Hoy en día existen múltiples técnicas para intentar subsanar este defecto. Una de ellas es la Técnica de Sloof. Hemos querido mostrar nuestros resultados con esta técnica. Material y métodos: Se revisaron 20 pacientes entre 1999 y octubre 2003 clasificados con la escala de Paprosky intervenidos con esta técnica. Se valoraron resultados en cuanto a mejoría del dolor, funcionalidad, actividad y consolidación radiológica, usando para ello las escalas de Harris. Resultados: La mayoría de los pacientes obtuvieron una mejoría significativa del dolor y una función suficiente como para realizar su vida de forma independiente, consiguiéndose la incorporación del injerto en todos los casos.Aim: The osteolysis of the pelvis is an important problem for the surgeon associated with acetabular revision. Nowadays there are many techniques which try to solve such a defect. One of them is the Sloof’s technique. We have shown our results using this technique. Materials and Methods: Study of 20 patients from 1999 to October 2003 who were treated with this technique. Results related to pain-free, functionality, activity and radiology consolidation, have been valued using Harris scale. Results: Most of patients got a significant pain diminution and a function enough to achieve their lives in a self- sufficiency way. We have obtained the graft incorporation in all the cases

Objetividad y biomejora humana. La paradoja de lo natural

Para el transhumanismo, la humanidad es una etapa que, guiada por la evolución biológica, estuvo precedida por otras anteriores y a la que seguirán otras nuevas. Según el transhumanismo hemos de romper la inercia de causas ciegas que gobierna la evolución y, a través de la biotecnología, alcanzar lo que denominan una “vida mejor”. Los autores afines a esta corriente desarrollan sus propuestas negando la existencia de una naturaleza humana, pero sin abandonar la convicción de que resulta posible definir en qué consiste una “vida mejor”. En este artículo analizamos la claridad y el rigor con la que presentan el fin último de su propuesta, la relación entre el fin y los medios planteados para alcanzarlo, y, finalmente, pondremos de manifiesto algunas inconsistencias derivadas de su rechazo de que la naturaleza humana pueda tener valor normativo.For transhumanism, humanity is a stage which, guided by biological evolution, was preceded by other earlier stages and which will be followed by others that are newer. According to transhumanism, we must break the inertia of blind causes that govern evolution and, through biotechnology, attain what is called a “better life”. Those authors who are supportive of this current of thought develop their proposals by negating the existence of a human nature, but without abandoning the conviction that it will be possible to define what a “better life” consists in. In this article we will analyze the clarity and rigor with which transhumanists present the ultimate goal of their proposal, the relation between the end and the means proposed for attaining it, and, finally, we will bring to light certain inconsistencies that result from their rejection of the position that human nature could have a normative value

Effectiveness of a home-based rehabilitation program after total hip arthroplasty driven by a tablet app and remote coaching:nonrandomized controlled trial combining a single-arm intervention cohort with historical controls

Background: Recent technological developments such as wearable sensors and tablets with a mobile internet connection hold promise for providing electronic health home-based programs with remote coaching for patients following total hip arthroplasty. It can be hypothesized that such a home-based rehabilitation program can offer an effective alternative to usual care. Objective: The aim of this study was to determine the effectiveness of a home-based rehabilitation program driven by a tablet app and remote coaching for patients following total hip arthroplasty. Methods: Existing data of two studies were combined, in which patients of a single-arm intervention study were matched with historical controls of an observational study. Patients aged 18-65 years who had undergone total hip arthroplasty as a treatment for primary or secondary osteoarthritis were included. The intervention consisted of a 12-week home-based rehabilitation program with video instructions on a tablet and remote coaching (intervention group). Patients were asked to do strengthening and walking exercises at least 5 days a week. Data of the intervention group were compared with those of patients who received usual care (control group). Effectiveness was measured at four moments (preoperatively, and 4 weeks, 12 weeks, and 6 months postoperatively) by means of functional tests (Timed Up & Go test and the Five Times Sit-to Stand Test) and self-reported questionnaires (Hip disability and Osteoarthritis Outcome Score [HOOS] and Short Form 36 [SF-36]). Each patient of the intervention group was matched with two patients of the control group. Patient characteristics were summarized with descriptive statistics. The 1:2 matching situation was analyzed with a conditional logistic regression. Effect sizes were calculated by Cohen d. Results: Overall, 15 patients of the intervention group were included in this study, and 15 and 12 subjects from the control group were matched to the intervention group, respectively. The intervention group performed functional tests significantly faster at 12 weeks and 6 months postoperatively. The intervention group also scored significantly higher on the subscales “function in sport and recreational activities” and “hip-related quality of life” of HOOS, and on the subscale “physical role limitations” of SF-36 at 12 weeks and 6 months postoperatively. Large effect sizes were found on functional tests at 12 weeks and at 6 months (Cohen d=0.5-1.2), endorsed by effect sizes on the self-reported outcomes. Conclusions: Our results clearly demonstrate larger effects in the intervention group compared to the historical controls. These results imply that a home-based rehabilitation program delivered by means of internet technology after total hip arthroplasty can be more effective than usual care

Reply to the discussion and comments of Azerêdo et al. (2023) and Schneider et al. (2023) on the paper by Magalhães et al. ‘Middle Jurassic multi-scale transgressive–regressive cycles: An example from the Lusitanian Basin’, The Depositional Record, 9, 174–202

cently published paper. The exchange of ideas, data and interpretation improves our knowledge and is the right way to discuss science\u27s advances. This reply considers the points raised by Azerêdo et al. (2023) and Schneider et al. (2023). In both manuscripts, these authors raised many issues about sedimentological and stratigraphic aspects that can be separated into two groups: (a) those related to the age of the studied succession; and (b) those assigning the studied succession to the Candeeiros Formation

Identification of quantitative trait loci for resistance against soybean sudden death syndrome caused by Fusarium tucumaniae

The objective of this work was to identify genomic regions that underlie resistance to Fusarium tucumaniae sp. nov., the causing agent of sudden death syndrome (SDS) in soybean in South America, using a population with a genetic background different from that previously reported for Fusarium virguliforme sp. nov. (F. solani f. sp. glycines), also responsible for SDS in soybean. Although major genes and quantitative trait loci (QTL) for SDS resistance have been identified, little is known about the same disease caused by Fusarium tucumaniae sp. nov., in South America. To identify genetic factors related to resistance to F. tucumaniae and DNA markers associated with them, a QTL analysis was performed using recombinant inbred lines. The map locations of the four loci, here identified, differed from those SDS resistance QTL previously described. It was screened a residual heterozygous line (RHL), which was heterozygous around the most effective QTL, RSDS1, and homozygous for the other genomic regions. The genetic effect of RSDS1 was confirmed using near-isogenic lines (NIL) derived from the RHL. The line which was homozygous for the Misuzudaizu genotype showed resistance levels comparable with that of the line homozygous for the Moshidou Gong 503 genotype

Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio

Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS

The chi_b(nP) quarkonium states are produced in proton-proton collisions at the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS detector. Using a data sample corresponding to an integrated luminosity of 4.4 fb^-1, these states are reconstructed through their radiative decays to Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes. This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table, corrected author list, matches final version in Physical Review Letter

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters

Measurement of the inclusive isolated prompt photon cross-section in pp collisions at sqrt(s)= 7 TeV using 35 pb-1 of ATLAS data

A measurement of the differential cross-section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy sqrt(s) = 7 TeV is presented. The measurement covers the pseudorapidity ranges |eta|<1.37 and 1.52<=|eta|<2.37 in the transverse energy range 45<=E_T<400GeV. The results are based on an integrated luminosity of 35 pb-1, collected with the ATLAS detector at the LHC. The yields of the signal photons are measured using a data-driven technique, based on the observed distribution of the hadronic energy in a narrow cone around the photon candidate and the photon selection criteria. The results are compared with next-to-leading order perturbative QCD calculations and found to be in good agreement over four orders of magnitude in cross-section.Comment: 7 pages plus author list (18 pages total), 2 figures, 4 tables, final version published in Physics Letters

Measurement of D*+/- meson production in jets from pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

This paper reports a measurement of D*+/- meson production in jets from proton-proton collisions at a center-of-mass energy of sqrt(s) = 7 TeV at the CERN Large Hadron Collider. The measurement is based on a data sample recorded with the ATLAS detector with an integrated luminosity of 0.30 pb^-1 for jets with transverse momentum between 25 and 70 GeV in the pseudorapidity range |eta| < 2.5. D*+/- mesons found in jets are fully reconstructed in the decay chain: D*+ -> D0pi+, D0 -> K-pi+, and its charge conjugate. The production rate is found to be N(D*+/-)/N(jet) = 0.025 +/- 0.001(stat.) +/- 0.004(syst.) for D*+/- mesons that carry a fraction z of the jet momentum in the range 0.3 < z < 1. Monte Carlo predictions fail to describe the data at small values of z, and this is most marked at low jet transverse momentum.Comment: 10 pages plus author list (22 pages total), 5 figures, 1 table, matches published version in Physical Review