28 research outputs found

    Tracing the patterns: fields, villages, and burial places in Lebanon

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    Archaeological research in Lebanon often focuses on settlement from the Bronze Age to Romanperiods, while surrounding landscapes, earlier and later periods are under-represented. Largedatasets collecting information from all periods and site types, such as the EndangeredArchaeology in the Middle East and North Africa (EAMENA) database, address this imbalance.EAMENA predominantly uses satellite imagery to identify archaeological sites and the threatsposed to them, leading to the recognition of many previously unpublished sites, includingabandoned buildings and agricultural terraces. Here we explore how such data can be used totrace patterns of settlement and landscape use. Transects running from coast to uplands innorthern and southern Lebanon are compared: the results show profound differences betweennorth and south, and between coastal and inland zones. The importance of large, holisticdatasets for previously understudied site types and periods in piecing together past patterns ofland use, subsistence economies, burial traditions and change over time are demonstrated

    Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

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    A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic

    Research needs in allergy: an EAACI position paper, in collaboration with EFA

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    Abstract In less than half a century, allergy, originally perceived as a rare disease, has become a major public health threat, today affecting the lives of more than 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting the budgets of public health systems. More disturbingly, its prevalence and impact are on the rise, a development that has been associated with environmental and lifestyle changes accompanying the continuous process of urbanization and globalization. Therefore, there is an urgent need to prioritize and concert research efforts in the field of allergy, in order to achieve sustainable results on prevention, diagnosis and treatment of this most prevalent chronic disease of the 21 st century. The European Academy of Allergy and Clinical Immunology (EAACI) is the leading professional organization in the field of allergy, promoting excellence in clinical care, education, training and basic and translational research, all with the ultimate goal of improving the health of allergic patients. The European Federation of Allergy and Airways Diseases Patients&apos; Associations (EFA) is a non-profit network of allergy, asthma and Chronic Obstructive Pulmonary Disorder (COPD) patients&apos; organizations. In support of their missions, the present EAACI Position Paper, in collaboration with EFA, highlights the most important research needs in the field of allergy to serve as key recommendations for future research funding at the national and European levels. Although allergies may involve almost every organ of the body and an array of diverse external factors act as triggers, there are several common themes that need to be prioritized in research efforts. As in many other chronic diseases, effective prevention, curative treatment and accurate, rapid diagnosis represent major unmet needs. Detailed phenotyping/endotyping stands out as widely required in order to arrange or re-categorize clinical syndromes into more coherent, uniform and treatment-responsive groups. Research efforts to unveil the basic pathophysiologic pathways and mechanisms, thus leading to the comprehension and resolution of the pathophysiologic complexity of allergies will allow for the design of novel patient-oriented diagnostic and treatment protocols. Several allergic diseases require well-controlled epidemiological description and surveillance, using disease registries, pharmacoeconomic evaluation, as well as large biobanks. Additionally, there is a need for extensive studies to bring promising new biotechnological innovations, such as biological agents, vaccines of modified allergen molecules and engineered components for allergy diagnosis, closer to clinical practice. Finally, particular attention should be paid to the difficult-to-manage, precarious and costly severe disease forms and/or exacerbations. Nonetheless, currently arising treatments, mainly in the fields of immunotherapy and biologicals, hold great promise for targeted and causal management of allergic conditions. Active involvement of all stakeholders, including Patient Organizations and policy makers are necessary to achieve the aims emphasized herein

    The Neolithic of the Jordanian Badia

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    Much research has been conducted in the arid zone of Jordan, beyond the Mediterranean environments traditionally understood as the Neolithic core developmental area. The Neolithic of this arid zone has often been framed as marginal, as specially adapted to the dry environmental conditions, as maintaining hunting traditions, as providing protein to the settled communities of the core, and as made possible by new developments in pastoralism. As more evidence is discovered, an increasingly nuanced picture emerges. Not least, our understanding of the environment suggests that rather than adaptation to arid conditions much of this Neolithic expansion may relate to the exploitation of extensive areas that were better watered than today. Nonetheless, new ways of living did emerge, although typically Neolithic in their intensification of the exploitation of resources leading to the carving out of new cultural and environmental niches. The relationships between people living in these lands and those living in the core established the foundations of the economic networks that become visible in the Chalcolithic and into the Early Bronze Age
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