664 research outputs found
Prescription appropriateness of anti-diabetes drugs in elderly patients hospitalized in a clinical setting: evidence from the REPOSI Register
- Author
- Agostino Gaudio
- Alberto Ballestrero
- Alberto Palazzuoli
- Alberto Panza
- Alberto Pilotto
- Alberto Zucchelli
- Aleandra Scozzafava
- Alessan- dro Delitala
- Alessandra Bettiol
- Alessandra Bonfanti
- Alessandra Danuta Di Mauro
- Alessandra Danuto Di Mauro
- Alessandra Grossi
- Alessandra Marengoni
- Alessandra Marengoni
- Alessandro Nobili
- Alessandro Squizzato
- Alessandro Vignali
- Alessandro Nobili
- Alessia Antonella Galbussera
- Alessia Cipollone
- Alessia Giotta
- Alessia Valentina Giraudo
- Alessio Comitangelo
- Alessio Molfino
- Alessio Novella
- Alessio Novella
- Alessio Novella
- Alfio Gennaro
- Alfredo De Giorgi
- Alice Valoriani
- Anastasia Xourafa
- Andrea Aglitti
- Andrea Falcetta
- Andrea Giovanni Ledda
- Andrea Maresca
- Andrea Piazzoli
- Andrea Schilardi
- Andrea Ticinesi
- Andrea Volpini
- Angela Sciacqua
- Angela Sciacqua
- Angelo Cocuzza
- Angelo Rizzo
- Angelo Simili
- Anna Linda Patti
- Anna Ludovica Fracanzani
- AnnaLicata
- Annalisa Cespiati
- Annalisa Pirozzi
- Antonella Giorgi
- Antonello Pietrangelo
- Antonello Pietrangelo
- Antonino Catalano
- Antonino Di Pino
- Antonio Brucato Teresa De Falco
- Antonio Di Sabatino
- Antonio Nouvenne
- Antonio Picardi
- Benedetta Boari
- Bianca Pari
- Bruno Tassone
- Camilla Scarsi
- Camillo Ferran- dina
- Carlo Custodero
- Carlo Sabbà
- Carlotta Franchi
- Carlotta Franchi
- Carmelinda Ruggiero
- Carmen Ricozzi
- Caterina Savriè
- Cesare Antonucci
- Chiara Lonati
- Chiara Maria Palmisano
- Chiara Sidoli
- Chiara Traversa
- Chiara Zurlo
- Christian Catalini
- Christian Folli
- Christian Gracin
- Christiano Argano
- Ciro Canetta
- Claudia Catalano
- Concetta Spichetti
- Concetto Principato
- Damiano D’Ardes
- Daniela Calipari
- Daniela Lucente
- Daniela Tirotta
- Daniele Sola
- Davide Firinu
- Davide Gonella
- Diletta Maira
- Domenico Cerminara
- Domenico Girelli
- Domenico Prisco
- Edoardo Pace
- Elena Silvestri
- Elena Spazzini
- Elena Succurro
- Elena Succurro
- Eleonora Mag- nolfi
- Eleonora Semproni
- Elisa Reni
- Elisabetta Cosi
- Elvira Clausi
- Emanuela Miceli
- Emanuele Amoruso
- Emanuele Valeriani
- Emilio Simeone
- Enrica Bozzolo
- Enrica Negro
- Enrico Petrillo
- Erica Larovere
- Erica Pagliaro
- Ermanno Ange- lucci
- Eugenio Ruggeri
- Fabiana Busti
- Fabio Fabbian
- Fabio Ferrando
- Fabio Tolloso
- Fabrizio Fabris
- Federica Bellone
- Federica Cacioppo
- Federica Cavallaro
- Federica Conti
- Federica Gandolfo
- Federica Giofrè
- Federica Giofrè
- Federico Cattaneo
- Federico Napoli
- Felice Cinque
- Filippo Alessandro Montalto
- Flora Peyvandi
- Francesca Alletto
- Francesca Coviello
- Francesca Manzoni
- Francesca Mazzeo
- Francesca Rotunno
- Francesco Baffa Bellucci
- Francesco Cipollone
- Francesco Corica
- Francesco Dentali
- Francesco Perticone
- Francesco Purrello
- Francesco Ratti
- Francesco Saverio Vella
- Francesco Violi
- Francesco Violi
- Francesco Andreozzi
- Franco Arturi
- Franco Laghi Pasini
- Franco Arturi
- Gabriella Miglio
- Gerardo Mancuso
- Giacomo Bartelloni
- Giacomo De Luca
- Giacomo Emmi
- Giacomo Marchi
- Gian Paolo Fra
- Giancarlo Labba- dia
- Gianni Biolo
- Gianpaolo Benzoni
- Ginevra Cambiè
- Gior- gio Basile
- Giordano Sigon
- Giorgio Sesti
- Giorgio Sesti
- Giovanna Eusebi
- Giovanna Fabio
- Giovanna Leoncini
- Giovanna Oberti
- Giovanni Imbimbo
- Giovanni Lorenzo Squintani
- Giovanni Michele De Vincenzo
- Giovanni Serafini
- Giulia Bogoni
- Giulia Bonini
- Giulia Cesaroni
- Giulia Colombo
- Giulia Cono
- Giulia Costanzo
- Giulia Marta Viglione
- Giulia Nobili
- Giulia Principato
- Giulia Van- nini
- Giulia Vigani
- Giuliana Ceriani
- Giuseppe Armentaro
- Giuseppe Bellelli
- Giuseppe Famularo
- Giuseppe Montalto
- Giuseppe Natoli
- Giuseppe Orio
- Giuseppe Paolisso
- Giuseppe Re
- Giuseppe Romanelli
- Graziana Lupattelli
- Hajnalka Szabo
- Ilaria Ardoino
- Ilaria Benzoni
- Ilaria Indiano
- Ilaria Lazzari
- Ilaria Martini
- Ilaria Rossi
- Irene Bertozzi
- Irene Di Meo
- Irene Mattioli
- Italia Aiello
- Ivano Barnaba
- Jacopo Alberto
- Jaqueline Currà
- Jessica Pepe
- Lavinia Pitotti
- Lavinia Pitotti
- Leonardo Campiotti
- Ligia Dominguez
- Lina Falanga
- Lorenzo Cerruti
- Luana Castiglioni
- Luca Pasina
- Luca Zanoli
- Lucia Colavolpe
- Lucia Esposito
- Lucia Sofia
- Lucia Trotta
- Luciano Colangelo
- Lucio Monaco
- Ludovica Perri
- Luigi Anastasio
- Luigi Fenoglio
- Luigina Guasti
- Maddalena Fabrizi
- Mar- tina Pisati
- Marco Novelli
- Marco Vincenzo Lenti
- Marco Zoli
- Margherita Migone De Amicis
- Maria Antonietta Bleve
- Maria Berria
- Maria Carbone
- Maria Domenica Cappellini
- Maria Grazia Serra
- Maria Laura Matacena
- Maria Luisa Randi
- Maria Perticone
- Maria Rosaria Rizzo
- Maria Stella Pisciotta
- Maria Teresa Guagnano
- Maria Victoria Rabuini
- Mario Barbagallo
- Mario Pirisi
- Marta Clerici
- Marta Mancarella
- Marta Sircana
- Martina Ruvio
- Martino Brenna
- Massimiliano Chiuch
- Massimo Porta
- Massimo R. Mannarino
- Massimo Raspanti
- Matteo Mazzetti
- Matteo Pirro
- Mattia Bellan
- Mattia Brunori
- Maurizio Corsi
- Maurizio Corsi
- Maurizio Muscaritoli
- Mauro Tettamanti
- Mauro Tettamanti
- Mauro Tettamanti
- Michela Zanetti
- Michele Zaccari
- Mirella Cilli
- Miriam Gino
- Miriana Martelengo
- Moreno Tresoldi
- Mosè Bartone
- Natalia Scaramellini
- Natalia Scaramellini
- Nicola Lucio Liberato
- Paola Nicolini
- Paolo Dionigi Rossi
- Paolo Gallo Violi
- Paolo Mazzola
- Paolo Setti
- Pasquale Agosti
- Patrizia Mecocci
- Patrizia Suppressa
- Patrizia Tarsitani
- Pier Leopoldo Capecchi
- Pier Mannuccio Mannucci
- Pietro Bocchi
- Pietro Castellino
- Raf- faele Maio
- Raffaella Rossio
- Ranuccio Nuti
- Renzo Rozzini
- Riccardo Alcidi
- Riccardo Mattia Ricciardi
- Riccardo Volpi
- Roberta Gonella
- Roberto Davide Diprizio
- Roberto Manetti
- Roberto Manfredini
- Roberto Pontremoli
- Roberto Quadri
- Roberto Tarquini
- Roberto Valenti
- Rosa Scurti
- Ruana Tiseo
- Sal- vatore Minisola
- Salva- tore Corrao
- Salvatore Chessa
- Salvatore Corrao
- Salvatore D’Aniano
- Salvatore Mularo
- Salvatore Piro
- Sara Angela Malerba
- Sara del Vecchio
- Sarah Damanti
- Serena Torre
- Sergio Harari
- Silvia Cantiero
- Silvia Cappelli
- Silvia Dolenti
- Silvia Prolo
- Silvia Tiraboschi
- Simona Leoni
- Simona Leoni
- Simona Leoni
- Simona Sestili
- Sonia Seghezzi
- Stefania Morra di Cella
- Stefano Boffelli
- Stefano Del Giacco
- Tancredi Prandini
- Teresa Salvatore
- Thelma Geneletti
- Tiziana Meschi
- Tiziana Morretti
- Tiziana Tognin
- Tiziano Lucchi
- Umberto Vespasiani Gentilucci
- Valentina Antoci
- Valentina Antoci
- Valentina Beccati
- Valentino Condoleo
- Valentino Condoleo
- Valeria Di Stefano
- Valeria Savojardo
- Valter Monzani
- Vanessa Bianconi
- Veronica Behnke
- Vincenza Beneduce
- Vincenzo Stanghellini
- Virginia Boccardi
- Vittorio Durante
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Diabetes is an increasing global health burden with the highest prevalence (24.0%) observed in elderly people. Older diabetic adults have a greater risk of hospitalization and several geriatric syndromes than older nondiabetic adults. For these conditions, special care is required in prescribing therapies including anti- diabetes drugs. Aim of this study was to evaluate the appropriateness and the adherence to safety recommendations in the prescriptions of glucose-lowering drugs in hospitalized elderly patients with diabetes. Data for this cross-sectional study were obtained from the REgistro POliterapie-Società Italiana Medicina Interna (REPOSI) that collected clinical information on patients aged ≥ 65 years acutely admitted to Italian internal medicine and geriatric non-intensive care units (ICU) from 2010 up to 2019. Prescription appropriateness was assessed according to the 2019 AGS Beers Criteria and anti-diabetes drug data sheets.Among 5349 patients, 1624 (30.3%) had diagnosis of type 2 diabetes. At admission, 37.7% of diabetic patients received treatment with metformin, 37.3% insulin therapy, 16.4% sulfonylureas, and 11.4% glinides. Surprisingly, only 3.1% of diabetic patients were treated with new classes of anti- diabetes drugs. According to prescription criteria, at admission 15.4% of patients treated with metformin and 2.6% with sulfonylureas received inappropriately these treatments. At discharge, the inappropriateness of metformin therapy decreased (10.2%, P < 0.0001). According to Beers criteria, the inappropriate prescriptions of sulfonylureas raised to 29% both at admission and at discharge. This study shows a poor adherence to current guidelines on diabetes management in hospitalized elderly people with a high prevalence of inappropriate use of sulfonylureas according to the Beers criteria
The “Diabetes Comorbidome”: A Different Way for Health Professionals to Approach the Comorbidity Burden of Diabetes
- Author
- Agostino Gaudio
- Alberto Ballestrero
- Alberto Palazzuoli
- Alberto Pilotto
- Alberto Zucchelli
- Aleandra Scozzafava
- Alessandra Bettiol
- Alessandra Bonfanti
- Alessandra Danuta Di Mauro
- Alessandra Danuto Di Mauro
- Alessandra Grossi
- Alessandra Marengoni
- Alessandro Delitala
- Alessandro Nobili
- Alessandro Squizzato
- Alessandro Vignali
- Alessia Giotta
- Alessia Valentina Giraudo
- Alessio Bragagni
- Alessio Comitangelo
- Alessio Greco
- Alessio Molfino
- Alfio Gennaro
- Alfredo De Giorgi
- Alice Valoriani
- Andrea Artoni
- Andrea Falcetta
- Andrea Maresca
- Andrea Piazzoli
- Andrea Salvi
- Andrea Schilardi
- Andrea Ticinesi
- Andrea Volpini
- Angela Sciacqua
- Angelo Simili
- Angelo Simili
- Anna Dal Col
- Anna L. Fracanzani
- Anna Licata
- Annalisa Cespiati
- Annalisa Pirozzi
- Antonella Afeltra
- Antonella Giorgi
- Antonino Catalano
- Antonino Di Pino
- Antonino Di Pino
- Antonio Brucato
- Antonio Di Sabatino
- Antonio Nouvenne
- Antonio Picardi
- Benedetta Boari
- Benedetta Marigliano
- Benedetta Stancanelli
- Bruno Graziella
- Bruno Tassone
- Camilla Scarsi
- Camillo Ferrandina
- Canetta Ciro
- Carl Margaria
- Carlo Custodero
- Carlo Sabbà
- Carmelinda Ruggiero
- Carmen Ricozzi
- Cesare Antonucci
- Cesare Poletto
- Chiara Dell’Unto
- Chiara Lonati
- Chiara Mussi
- Chiara Sidoli
- Chiara Traversa
- Chiara Zurlo
- Christian Folli
- Christian Gracin
- Christiano Argano
- Claudia Catalano
- Claudio Borghi
- Concetto Principato
- Costanza Caccia Dominioni
- Cristina Fasolino
- Damiani D’Ardes
- Daniela Calipari
- Daniela Lucente
- Daniela Tirotta
- Daniele Sola
- Davide Firinu
- Devis Benfaremo
- Diletta Maira
- Domenico Cerminara
- Domenico Girelli
- Domenico Prisco
- Donatella Padula
- Edoardo Alessandro Pulixi
- Edoardo Favale
- Elena Bigi
- Elena Silvestri
- Elena Spazzini
- Elena Succurro
- Eleonora Magnolfi
- Elisa Pellegrini
- Elisabetta Cosi
- Elvira Clausi
- Emanuela Miceli
- Emanuele Amoruso
- Emanuele Filippini
- Emanuele Valeriani
- Emilio Simeone
- Enrica Bozzolo
- Enrica Negro
- Enrico Petrillo
- Enrico Strocchi
- Erica Larovere
- Erica Pagliaro
- Ermanno Angelucci
- Eugenia Ianniello
- Eugenio Ruggeri
- Fabiana Busti
- Fabio Fabbian
- Fabio Ferrando
- Fabio Tolloso
- Fabrizio Fabris
- Fabrizio Montecucco
- Federica Bellone
- Federica Caciopp
- Federica Conti
- Federica Gandolfo
- Federica Giofrè
- Federico Cattaneo
- Federico Napoli
- Felice Cinque
- Filippo Alessandro Montalto
- Flora Peyvandi
- Francesca Giulia Leoni
- Francesca Loparco
- Francesca Losa
- Francesca Manzoni
- Francesca Mazzeo
- Francesca Mete
- Francesca Rotunno
- Francesco Baffa Bellucci
- Francesco Cipollone
- Francesco Corica
- Francesco Dentali
- Francesco Perticone
- Francesco Purrello
- Francesco Purrello
- Francesco Ratti
- Francesco Salerno
- Francesco Saverio Vella
- Francesco Violi
- Franco Arturi
- Franco Berti
- Franco Laghi Pasini
- Gabriella D’Aurizio
- Gabriella Gruden
- Gerardo Mancuso
- Giacomo Argiolas
- Giacomo Bartelloni
- Giacomo De Luca
- Giacomo Emmi
- Giacomo Marchi
- Giacomo Zaccherini
- Giada Pallini
- Giampaolo Damiani
- Gian Paolo Ceda
- Gian Paolo Fra
- Giancarlo Labbadia
- Giandomenico Nigro Imperiale
- Gianluca Moroncini
- Gianni Biolo
- Giordano Sigon
- Giorgio Basile
- Giovanna Eusebi
- Giovanna Fabio
- Giovanna Leoncini
- Giovanna Oberti
- Giovanni Imbimbo
- Giovanni Lorenzo Squintani
- Giovanni Michele De Vincenzo
- Giovanni Paoletti
- Giovanni Serafini
- Giulia Bogoni
- Giulia Bonini
- Giulia Cesaroni
- Giulia Colombo
- Giulia Cono
- Giulia Costanzo
- Giulia Dondi
- Giulia Grignani
- Giulia Lancellotti
- Giulia Nobili
- Giulia Principato
- Giulia Vannini
- Giulia Vigani
- Giulia Vischi
- Giuliana Ceriani
- Giuseppe Bellelli
- Giuseppe Delitala
- Giuseppe Famularo
- Giuseppe Montalto
- Giuseppe Montrucchio
- Giuseppe Natoli
- Giuseppe Orio
- Giuseppe Paolisso
- Giuseppe Pio Martino
- Giuseppe Re
- Giuseppe Romanelli
- Giuseppe Zuccalà
- Gloria Pina
- Graziana Lupattelli
- Guido Moreo
- Hajnalka Szabo
- Ilaria Benzoni
- Ilaria Indiano
- Ilaria Lazzari
- Ilaria Rossi
- Ilenia Pareo
- Irene Bertozzi
- Irene Di Meo
- Irene Mattioli
- Italia Aiello
- Jacopo Alberto
- Lara Caserza
- Lara La Malfa
- Laura Orlandi
- Lavinia Pitotti
- Leonardo Campiotti
- Lidia Colangelo
- Ligia Dominguez
- Lina Falanga
- Lorenzo Biondi
- Lorenzo Cerruti
- Lorenzo Malatino
- Luana Castiglioni
- Luca Liberale
- Luca Santi
- Luca Zanoli
- Lucia Carulli
- Lucia Esposito
- Lucia Sofia
- Lucia Trotta
- Luciano Colangelo
- Luciano Ottonello
- Lucio Monaco
- Ludovica Perri
- Luigi Anastasio
- Luigi Fenoglio
- Luigi Fondrieschi
- Luigina Guasti
- Maddalena Fabrizi
- Marcello Giuseppe Maggio
- Marco Bertolotti
- Marco Cattaneo
- Marco Filice
- Marco Novelli
- Marco Vincenzo Lenti
- Marco Zoli
- Margherita Grossi
- Margherita Migone De Amicis
- Maria Antonietta Bleve
- Maria Berria
- Maria Carbone
- Maria Domenica Cappellini
- Maria Elena Pipita
- Maria Grazia Serra
- Maria Laura Matacena
- Maria Luisa Randi
- Maria Perticone
- Maria Rosaria Rizzo
- Maria Stella Pisciotta
- Maria Teresa Guagnano
- Maria Valentina Amoruso
- Maria Victoria Rabuini
- Maria Vittoria Libbra
- Mario Barbagallo
- Mario Pirisi
- Mario Soldati
- Marta Clerici
- Marta Mancarella
- Martina Pisati
- Martina Ruvio
- Martino Brenna
- Massimiliano Chiuch
- Massimo Mattioli
- Massimo Porta
- Massimo R. Mannarino
- Massimo Raspanti
- Massimo Vanoli
- Matteo Galassi
- Matteo Pirro
- Mattia Bellan
- Mattia Brunori
- Maura Sanino
- Maurizio Corsi
- Maurizio Corsi
- Maurizio Muscaritoli
- Mauro Bernardi
- Michela Cammarosano
- Michela Pasino
- Michela Zanetti
- Michele Zaccari
- Mirella Cilli
- Miriam Gino
- Miriam Gino.
- Miriana Martelengo
- Monica Ormas
- Moreno Tresoldi
- Mosè Bartone
- Natalia Scaramellini
- Nicola Lucio Liberato
- Paola Fracasso
- Paolo Dionigi Rossi
- Paolo Gallo
- Paolo Mazzola
- Paolo Peasso
- Paolo Setti
- Pasquale Agosti
- Patrizia Mecocci
- Patrizia Suppressa
- Patrizia Tarsitani
- Pier Leopoldo Capecchi
- Pier Mannuccio Mannucci
- Pietro Bocchi
- Pietro Castellino
- Pietro Minuz
- Pietro Pettinari
- Raffaele Maio
- Raffaella Rossio
- Ranuccio Nuti
- Renzo Rozzini
- Riccardo Alcidi
- Riccardo Ghio
- Riccardo Volpi
- Roberta Gonella
- Roberto Castello
- Roberto Davide Diprizio
- Roberto Leonardi
- Roberto Manfredini
- Roberto Pontremoli
- Roberto Quadri
- Roberto Romiti
- Roberto Tarquini
- Roberto Valenti
- Rosa Battaglia
- Rosa Scurti
- Rosario Di Quattro
- Rossella Caruso
- Ruana Tiseo
- Salam Kassem
- Salvatore Corrao
- Salvatore Di Marca
- Salvatore D’Aniano
- Salvatore Fragapani
- Salvatore Minisola
- Salvatore Mularo
- Salvatore Piro
- Samuele Pignataro
- Sara del Vecchio
- Sara Scarduelli
- Sarah Damanti
- Sarah Morellini
- Sergio Harari
- Silvia Cappelli
- Silvia Dolenti
- Silvia Li Bassi
- Silvia Prolo
- Silvia Prolo
- Silvia Schiavone
- Silvia Tiraboschi
- Simona Leoni
- Simona Leoni
- Simona Sestili
- Simonetta Morganti
- Sonia Seghezzi
- Stefano Baldassarre
- Stefano Buffelli
- Stefano Del Giacco
- Tancredi Prandini
- Tania Falbo
- Teresa De Falco
- Teresa Salvatore
- Tiziana Meschi
- Tiziana Tognin
- Tiziano Lucchi
- Umberto Vespasiani Gentilucci
- Valentina Beccati
- Valentina Terranova
- Valentino Condoleo
- Valeria De Sando
- Valeria Di Stefano
- Valeria Savojardo
- Valter Monzani
- Vanessa Bianconi
- Vincenza Beneduce
- Vincenzo Arcoraci
- Vincenzo Stanghellini
- Virginia Boccardi
- Vittorio Durante
- William Capeci
- Yasmine Grassi
- Publication venue
- Publication date
- 01/01/2022
- Field of study
(1) Background: The disease burden related to diabetes is increasing greatly, particularly in older subjects. A more comprehensive approach towards the assessment and management of diabetes’ comorbidities is necessary. The aim of this study was to implement our previous data identifying and representing the prevalence of the comorbidities, their association with mortality, and the strength of their relationship in hospitalized elderly patients with diabetes, developing, at the same time, a new graphic representation model of the comorbidome called “Diabetes Comorbidome”. (2) Methods: Data were collected from the RePoSi register. Comorbidities, socio-demographic data, severity and comorbidity indexes (Cumulative Illness rating Scale CIRS-SI and CIRS-CI), and functional status (Barthel Index), were recorded. Mortality rates were assessed in hospital and 3 and 12 months after discharge. (3) Results: Of the 4714 hospitalized elderly patients, 1378 had diabetes. The comorbidities distribution showed that arterial hypertension (57.1%), ischemic heart disease (31.4%), chronic renal failure (28.8%), atrial fibrillation (25.6%), and COPD (22.7%), were the more frequent in subjects with diabetes. The graphic comorbidome showed that the strongest predictors of death at in hospital and at the 3-month follow-up were dementia and cancer. At the 1-year follow-up, cancer was the first comorbidity independently associated with mortality. (4) Conclusions: The “Diabetes Comorbidome” represents the perfect instrument for determining the prevalence of comorbidities and the strength of their relationship with risk of death, as well as the need for an effective treatment for improving clinical outcomes
Antidiabetic Drug Prescription Pattern in Hospitalized Older Patients with Diabetes
- Author
- Agostino Gaudio
- Alberto Ballestrero
- Alberto Palazzuoli
- Alberto Pilotto
- Alberto Zucchelli
- Aleandra Scozzafava
- Alessandra Bettiol
- Alessandra Bonfanti
- Alessandra Danuta Di Mauro
- Alessandra Danuto Di Mauro
- Alessandra Grossi
- Alessandra Marengoni
- Alessandro Delitala
- Alessandro Nobili
- Alessandro Squizzato
- Alessandro Vignali
- Alessia Giotta
- Alessia Valentina Giraudo
- Alessio Bragagni
- Alessio Comitangelo
- Alessio Greco
- Alessio Molfino
- Alfio Gennaro
- Alfredo De Giorgi
- Alice Valoriani
- Andrea Artoni
- Andrea Falcetta
- Andrea Maresca
- Andrea Piazzoli
- Andrea Salvi
- Andrea Schilardi
- Andrea Ticinesi
- Andrea Volpini
- Angela Sciacqua
- Angelo Simili
- Anna Dal Col
- Anna L. Fracanzani
- Anna Licata
- Annalisa Cespiati
- Annalisa Pirozzi
- Antonella Afeltra
- Antonella Giorgi
- Antonino Catalano
- Antonino Di Pino
- Antonino Di Pino
- Antonio Brucato
- Antonio Di Sabatino
- Antonio Nouvenne
- Antonio Picardi
- Benedetta Boari
- Benedetta Marigliano
- Benedetta Stancanelli
- Bruno Graziella
- Bruno Tassone
- Camilla Scarsi
- Camillo Ferrandina
- Canetta Ciro
- Carl Margaria
- Carlo Custodero
- Carlo Sabbà
- Carlotta Franchi
- Carmelinda Ruggiero
- Carmen Ricozzi
- Cesare Antonucci
- Cesare Poletto
- Chiara Dell’Unto
- Chiara Lonati
- Chiara Mussi
- Chiara Sidoli
- Chiara Traversa
- Chiara Zurlo
- Christian Folli
- Christian Gracin
- Christiano Argano
- Claudia Catalano
- Claudio Borghi
- Concetto Principato
- Costanza Caccia Dominioni
- Cristina Fasolino
- Damiani D’Ardes
- Daniela Calipari
- Daniela Lucente
- Daniela Tirotta
- Daniele Sola
- Davide Firinu
- Devis Benfaremo
- Diletta Maira
- Domenico Cerminara
- Domenico Girelli
- Domenico Prisco
- Donatella Padula
- Edoardo Alessandro Pulixi
- Edoardo Favale
- Elena Bigi
- Elena Silvestri
- Elena Spazzini
- Elena Succurro
- Eleonora Magnolfi
- Elisa Pellegrini
- Elisabetta Cosi
- Elvira Clausi
- Emanuela Miceli
- Emanuele Amoruso
- Emanuele Filippini
- Emanuele Valeriani
- Emilio Simeone
- Enrica Bozzolo
- Enrica Negro
- Enrico Petrillo
- Enrico Strocchi
- Erica Larovere
- Erica Pagliaro
- Ermanno Angelucci
- Eugenia Ianniello
- Eugenio Ruggeri
- Fabiana Busti
- Fabio Fabbian
- Fabio Ferrando
- Fabio Tolloso
- Fabrizio Fabris
- Fabrizio Montecucco
- Federica Bellone
- Federica Cacioppo
- Federica Cavallaro
- Federica Conti
- Federica Gandolfo
- Federica Giofrè
- Federico Cattaneo
- Federico Napoli
- Felice Cinque
- Filippo Alessandro Montalto
- Flora Peyvandi
- Francesca Giulia Leoni
- Francesca Loparco
- Francesca Losa
- Francesca Manzoni
- Francesca Mazzeo
- Francesca Mete
- Francesco Baffa Bellucci
- Francesco Cipollone
- Francesco Corica
- Francesco Dentali
- Francesco Purrello
- Francesco Purrello
- Francesco Ratti
- Francesco Salerno
- Francesco Saverio Vella
- Francesco Violi
- Franco Arturi
- Franco Berti
- Franco Laghi Pasini
- Gabriella D’Aurizio
- Gabriella Gruden
- Gerardo Mancuso
- Giacomo Argiolas
- Giacomo Bartelloni
- Giacomo De Luca
- Giacomo Emmi
- Giacomo Marchi
- Giacomo Zaccherini
- Giada Pallini
- Giampaolo Damiani
- Gian Paolo Fra
- Giancarlo Labbadia
- Giandomenico Nigro Imperiale
- Gianluca Moroncini
- Gianni Biolo
- Giordano Sigon
- Giorgio Basile
- Giovanna Eusebi
- Giovanna Fabio
- Giovanna Leoncini
- Giovanna Oberti
- Giovanni Imbimbo
- Giovanni Michele De Vincenzo
- Giovanni Paoletti
- Giovanni Serafini
- Giulia Bogoni
- Giulia Bonini
- Giulia Cesaroni
- Giulia Colombo
- Giulia Cono
- Giulia Costanzo
- Giulia Dondi
- Giulia Grignani
- Giulia Lancellotti
- Giulia Nobili
- Giulia Principato
- Giulia Vannini
- Giulia Vigani
- Giulia Vischi
- Giuliana Ceriani
- Giuseppe Bellelli
- Giuseppe Delitala
- Giuseppe Famularo
- Giuseppe Montalto
- Giuseppe Montrucchio
- Giuseppe Natoli
- Giuseppe Orio
- Giuseppe Paolisso
- Giuseppe Pio Martino
- Giuseppe Re
- Giuseppe Romanelli
- Giuseppe Zuccalà
- Gloria Pina
- Graziana Lupattelli
- Guido Moreo
- Hajnalka Szabo
- Ilaria Ardoino
- Ilaria Benzoni
- Ilaria Indiano
- Ilaria Lazzari
- Ilaria Rossi
- Ilenia Pareo
- Irene Bertozzi
- Irene Di Meo
- Irene Mattioli
- Italia Aiello
- Jacopo Alberto
- Lara Caserza
- Lara La Malfa
- Laura Orlandi
- Lavinia Pitotti
- Leonardo Campiotti
- Lidia Colangelo
- Ligia Dominguez
- Lina Falanga
- Lorenzo Biondi
- Lorenzo Cerruti
- Lorenzo Malatino
- Luana Castiglioni
- Luca Liberale
- Luca Santi
- Luca Zanoli
- Lucia Carulli
- Lucia Esposito
- Lucia Sofia
- Lucia Trotta
- Luciano Colangelo
- Luciano Ottonello
- Lucio Monaco
- Ludovica Perri
- Luigi Anastasio
- Luigi Fenoglio
- Luigi Fondrieschi
- Luigina Guasti
- Maddalena Fabrizi
- Marcello Giuseppe Maggio Gian Paolo Ceda
- Marco Bertolotti
- Marco Cattaneo
- Marco Filice
- Marco Novelli
- Marco Vincenzo Lenti
- Marco Zoli
- Margherita Grossi
- Margherita Migone De Amicis
- Maria Antonietta Bleve
- Maria Berria
- Maria Carbone
- Maria Domenica Cappellini
- Maria Elena Pipita
- Maria Grazia Serra
- Maria Laura Matacena
- Maria Luisa Randi
- Maria Perticone
- Maria Rosaria Rizzo
- Maria Stella Pisciotta
- Maria Teresa Guagnano
- Maria Valentina Amoruso
- Maria Victoria Rabuini
- Maria Vittoria Libbra
- Mario Barbagallo
- Mario Pirisi
- Mario Soldati
- Marta Baviera
- Marta Clerici
- Marta Mancarella
- Martina Pisati
- Martina Ruvio
- Martino Brenna
- Massimiliano Chiuch
- Massimo Mattioli
- Massimo Porta
- Massimo R. Mannarino
- Massimo Raspanti
- Massimo Vanoli
- Matteo Galassi
- Matteo Pirro
- Mattia Bellan
- Mattia Brunori
- Maura Sanino
- Maurizio Corsi
- Maurizio Corsi
- Maurizio Muscaritoli
- Mauro Bernardi
- Michela Cammarosano
- Michela Pasino
- Michela Zanetti
- Michele Zaccari
- Mirella Cilli
- Miriam Gino
- Miriam Gino.
- Miriana Martelengo
- Monica Ormas
- Moreno Tresoldi
- Mosè Bartone
- Natalia Scaramellini
- Nicola Lucio Liberato
- Paola Fracasso
- Paolo Dionigi Rossi
- Paolo Gallo
- Paolo Mazzola
- Paolo Peasso
- Paolo Setti
- Pasquale Agosti
- Patrizia Mecocci
- Patrizia Suppressa
- Patrizia Tarsitani
- Pier Leopoldo Capecchi
- Pier Mannuccio Mannucci
- Pietro Bocchi
- Pietro Castellino
- Pietro Minuz
- Pietro Pettinari
- Raffaele Maio
- Raffaella Rossio
- Ranuccio Nuti
- Renzo Rozzini
- Riccardo Alcidi
- Riccardo Ghio
- Riccardo Volpi
- Roberta Gonella
- Roberto Castello
- Roberto Davide Diprizio
- Roberto Leonardi
- Roberto Manfredini
- Roberto Pontremoli
- Roberto Quadri
- Roberto Romiti
- Roberto Tarquini
- Roberto Valenti
- Rosa Battaglia
- Rosa Scurti
- Rosario Di Quattro
- Rossella Caruso
- Ruana Tiseo
- Salam Kassem
- Salvatore Corrao
- Salvatore Di Marca
- Salvatore D’Aniano
- Salvatore Fragapani
- Salvatore Minisola
- Salvatore Mularo
- Salvatore Piro
- Samuele Pignataro
- Sara del Vecchio
- Sara Mandelli
- Sara Scarduelli
- Sarah Damanti
- Sarah Morellini
- Sergio Harari
- Silvia Cappelli
- Silvia Dolenti
- Silvia Li Bassi
- Silvia Prolo
- Silvia Prolo
- Silvia Schiavone
- Silvia Tiraboschi
- Simona Leoni
- Simona Leoni
- Simona Sestili
- Simonetta Morganti
- Sonia Seghezzi
- Stefano Baldassarre
- Stefano Buffelli
- Stefano Del Giacco
- Tancredi Prandini
- Tania Falbo
- Teresa De Falco
- Teresa Salvatore
- Tiziana Meschi
- Tiziana Tognin
- Tiziano Lucchi
- Umberto Vespasiani Gentilucci
- Valentina Beccati
- Valentina Terranova
- Valentino Condoleo
- Valeria De Sando
- Valeria Di Stefano
- Valeria Savojardo
- Valter Monzani
- Vanessa Bianconi
- Vincenza Beneduce
- Vincenzo Stanghellini
- Virginia Boccardi
- Vittorio Durante
- William Capeci
- Yasmine Grassi
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Objective: To describe the prescription pattern of antidiabetic and cardiovascular drugs in a cohort of hospitalized older patients with diabetes. Methods: Patients with diabetes aged 65 years or older hospitalized in internal medicine and/or geriatric wards throughout Italy and enrolled in the REPOSI (REgistro POliterapuie SIMI—Società Italiana di Medicina Interna) registry from 2010 to 2019 and discharged alive were included. Results: Among 1703 patients with diabetes, 1433 (84.2%) were on treatment with at least one antidiabetic drug at hospital admission, mainly prescribed as monotherapy with insulin (28.3%) or metformin (19.2%). The proportion of treated patients decreased at discharge (N = 1309, 76.9%), with a significant reduction over time. Among those prescribed, the proportion of those with insulin alone increased over time (p = 0.0066), while the proportion of those prescribed sulfonylureas decreased (p < 0.0001). Among patients receiving antidiabetic therapy at discharge, 1063 (81.2%) were also prescribed cardiovascular drugs, mainly with an antihypertensive drug alone or in combination (N = 777, 73.1%). Conclusion: The management of older patients with diabetes in a hospital setting is often sub-optimal, as shown by the increasing trend in insulin at discharge, even if an overall improvement has been highlighted by the prevalent decrease in sulfonylureas prescription
Beta-Blocker Use in Older Hospitalized Patients Affected by Heart Failure and Chronic Obstructive Pulmonary Disease: An Italian Survey From the REPOSI Register
- Author
- Agostino Gaudio
- Alberto Ballestrero
- Alberto Pilotto
- Alessandra Bettiol
- Alessandra Danuta Di Mauro
- Alessandra Grossi
- Alessandra Marengoni
- Alessandro Cavarape
- Alessandro Delitala
- Alessandro Nobili
- Alessandro Squizzato
- Alessandro Vignali
- Alessio Bragagni
- Alessio Comitangelo
- Alessio Greco
- Alessio Molfino
- Alessio Novella
- Alfio Gennaro
- Alfredo De Giorgi
- Alice Valoriani
- Andea Da Porto
- Andrea Artoni
- Andrea Falcetta
- Andrea Maresca
- Andrea Salvi
- Andrea Ticinesi
- Andrea Volpini
- Angela Sciacqua
- Angelo Simili
- Anna Dal Col
- Anna L. Fracanzani
- Anna Licata
- Annalisa Cespiati
- Antonella Afeltra
- Antonella Giorgi
- Antonello Pietrangelo
- Antonino Catalano
- Antonino Di Pino
- Antonino Di Pino
- Antonio Brucato
- Antonio Cittadini
- Antonio Di Sabatino
- Antonio Mirijello
- Antonio Nouvenne
- Antonio Picardi
- Benedetta Boari
- Benedetta Marigliano
- Benedetta Stancanelli
- Bruno Graziella
- Bruno Tassone
- Carl Margaria
- Carla Di Gennaro
- Carlo Bussolino
- Carlo Custodero
- Carlo Sabbà
- Carlo Vigorito
- Carlotta Franchi
- Carmelinda Ruggiero
- Carmen Ricozzi
- Caterina Mengoli
- Cesare Antonucci
- Cesare Poletto
- Chiara Lonati
- Chiara Mussi
- Chiara Sidoli
- Christian Gracin
- Christiano Argano
- Claudia Catalano
- Claudio Borghi
- Concetto Principato
- Costanza Caccia Dominioni
- Cristian Petri
- Cristiana Catena
- Daniela Calipari
- Daniela Lucente
- Daniele Sola
- Davide Firinu
- Domenico Cerminara
- Domenico Girelli
- Domenico Prisco
- Edoardo Alessandro Pulixi
- Edoardo Favale
- Elena Silvestri
- Elena Succurro
- Eleonora Magnolfi
- Emanuela Miceli
- Emanuele Amoruso
- Emilio Simeone
- Enrico Petrillo
- Enrico Strocchi
- Erica Larovere
- Eugenia Ianniello
- Eugenio Ruggeri
- Fabiana Busti
- Fabio Fabbian
- Fabio Ferrando
- Fabio Tolloso
- Fabrizio Fabris
- Fabrizio Montecucco
- Federica Bellone
- Federica Cacioppo
- Federica Gandolfo.
- Federica Giofrè
- Federico Napoli
- Filippo Alessandro Montalto
- Flora Peyvandi
- Francesca Mete
- Francesco Baffa Bellucci
- Francesco Cipollone
- Francesco Corica
- Francesco Nasso
- Francesco Perticone
- Francesco Purrello
- Francesco Purrello
- Francesco Salerno
- Francesco Saverio Vella
- Francesco Squadrito
- Francesco Violi
- Franco Arturi
- Franco Berti
- Gabriele Mascherini
- Gabriella D'Aurizio
- Gabriella Gruden
- Gabriella Miglio
- Gerardo Mancuso
- Giacomo Argiolas
- Giacomo Bartelloni
- Giacomo De Luca
- Giacomo Emmi
- Giacomo Marchi
- Giada Pallini
- Giampaolo Damiani
- Gian Paolo Ceda
- Gian Paolo Fra
- Giancarlo Labbadia
- Giandomenico Nigro Imperiale
- Gianluca Colussi
- Gianni Biolo
- Gino Roberto Corazza
- Giordano Sigon
- Giorgio Basile
- Giorgio Galanti
- Giorgio Scanzi
- Giovanna Fabio
- Giovanna Leoncini
- Giovanna Oberti
- Giovanni Michele De Vincenzo
- Giovanni Pallio
- Giovanni Serafini
- Giovanni Squadrito
- Giulia Bogoni
- Giulia Colombo
- Giulia Costanzo
- Giulia Grignani
- Giulia Lancellotti
- Giulia Nobili
- Giulia Principato
- Giulia Vannini
- Giulia Vischi
- Giuliana Ceriani
- Giuseppe Bellelli
- Giuseppe Delitala
- Giuseppe Famularo
- Giuseppe Licata
- Giuseppe Montalto
- Giuseppe Montrucchio
- Giuseppe Natoli
- Giuseppe Orio
- Giuseppe Palasciano
- Giuseppe Paolisso
- Giuseppe Pio Martino
- Giuseppe Romanelli
- Giuseppe Zuccalà
- Gloria Pina
- Graziana Lupattelli
- Guido Moreo
- Ilaria Ardoino
- Ilaria Indiano
- Ilaria Rossi
- Irene Bertozzi
- Irene Mattioli
- Italia Aiello
- Lara Caserza
- Lara La Malfa
- Laura Cortesi
- Laura Ricevuti
- Laura Stefani
- Leonardo Campiotti
- Leonardo Sechi
- Ligia Dominguez
- Lina Falanga
- Lorenzo Biondi
- Lorenzo Malatino
- Luana Castiglioni
- Luca Pasina
- Luca Rinaldi
- Luca Zanoli
- Lucia Sofia
- Luciano Colangelo
- Luciano Ottonello
- Lucio Monaco
- Ludovica Perri
- Luigi Anastasio
- Luigi Fenoglio
- Luigi Fondrieschi
- Luigina Guasti
- Marcello Giuseppe Maggio
- Marco Bertolotti
- Marco Novelli
- Marco Vincenzo Lenti
- Marco Zoli
- Margherita Girino
- Margherita Grossi
- Margherita Migone De Amicis
- Maria Antonietta Barbieri
- Maria Antonietta Bleve
- Maria Berria
- Maria Carbone
- Maria Cristina Nava
- Maria Domenica Cappellini
- Maria Elena Pipita
- Maria Ester Modeo
- Maria Grazia Serra
- Maria Laura Matacena
- Maria Pasquale
- Maria Perticone
- Maria Rosaria Rizzo
- Maria Stella Pisciotta
- Maria Teresa Guagnano
- Maria Victoria Rabuini
- Maria Vittoria Libbra
- Mario Barbagallo
- Mario Pirisi
- Mario Soldati
- Marisa Fogliati
- Marta Clerici
- Martina Pisati
- Massimo Mattioli
- Massimo Montalto
- Massimo Porta Piero Riva
- Massimo Raspanti
- Massimo Vanoli
- Matteo Cesari
- Matteo Galassi
- Mattia Bellan
- Maura Sanino
- Maurizio Corsi
- Maurizio Muscaritoli
- Mauro Tettamanti
- Michela Pasino
- Michela Zanetti
- Michelangelo Rottura
- Mirella Cilli
- Miriam Gino
- Mosè Bartone
- Natalia Scaramellini
- Natasha Irrera
- Nicola Lucio Liberato
- Nicola Passariello
- Paolo Dionigi Rossi
- Paolo Gallo
- Paolo Peasso
- Pasquale Agosti
- Patrizia Mecocci
- Patrizia Suppressa
- Patrizia Tarsitani
- Pier Mannuccio Mannucci
- Pietro Bocchi
- Pietro Castellino
- Pietro Minuz
- Pietro Pettinari
- Raffaele Landolfi
- Raffaele Maio
- Raffaella Rossio
- Renzo Rozzini
- Riccardo Alcidi
- Riccardo Ghio
- Riccardo Volpi
- Roberta Gonella
- Roberto Castello
- Roberto Davide Diprizio
- Roberto Leonardi
- Roberto Manfredini
- Roberto Pontremoli
- Roberto Quadri
- Roberto Tarquini
- Rosa Battaglia
- Rosa Scurti
- Rosario Di Quattro
- Rossella Caruso
- Ruana Tiseo
- Salvatore Corrao
- Salvatore Di Marca
- Salvatore Fragapani
- Salvatore Minisola
- Salvatore Mularo
- Salvatore Piro
- Sara del Vecchio
- Sarah Damanti
- Sergio Berra
- Sergio Harari
- Silvia Dolenti
- Silvia Ghidoni
- Silvia Prolo
- Silvia Schiavone
- Silvia Tiraboschi
- Simona Leoni
- Simonetta Dassi
- Simonetta Morganti
- Stefano Baldassarre
- Stefano Buffelli
- Stefano Del Giacco
- Stella Provini
- Tancredi Prandini
- Teresa De Falco
- Teresa Salvatore
- Tiziana Meschi
- Tiziana Tognin
- Umberto Vespasiani Gentilucci
- Valentina Beccati
- Valentina Terranova
- Valeria Piccinelli
- Valeria Savojardo
- Valter Monzani
- Valter Saracco
- Vanessa Bianconi
- Vincenza Beneduce
- Vincenza Gioffrè
- Vincenzo Arcoraci
- Vincenzo Stanghellini
- Virginia Boccardi
- William Capeci
- Yasmine Grassi
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Beta (β)-blockers (BB) are useful in reducing morbidity and mortality in patients with heart failure (HF) and concomitant chronic obstructive pulmonary disease (COPD). Nevertheless, the use of BBs could induce bronchoconstriction due to β2-blockade. For this reason, both the ESC and GOLD guidelines strongly suggest the use of selective β1-BB in patients with HF and COPD. However, low adherence to guidelines was observed in multiple clinical settings. The aim of the study was to investigate the BBs use in older patients affected by HF and COPD, recorded in the REPOSI register. Of 942 patients affected by HF, 47.1% were treated with BBs. The use of BBs was significantly lower in patients with HF and COPD than in patients affected by HF alone, both at admission and at discharge (admission, 36.9% vs. 51.3%; discharge, 38.0% vs. 51.7%). In addition, no further BB users were found at discharge. The probability to being treated with a BB was significantly lower in patients with HF also affected by COPD (adj. OR, 95% CI: 0.50, 0.37-0.67), while the diagnosis of COPD was not associated with the choice of selective β1-BB (adj. OR, 95% CI: 1.33, 0.76-2.34). Despite clear recommendations by clinical guidelines, a significant underuse of BBs was also observed after hospital discharge. In COPD affected patients, physicians unreasonably reject BBs use, rather than choosing a β1-BB. The expected improvement of the BB prescriptions after hospitalization was not observed. A multidisciplinary approach among hospital physicians, general practitioners, and pharmacologists should be carried out for better drug management and adherence to guideline recommendations
Clinical features and outcomes of elderly hospitalised patients with chronic obstructive pulmonary disease, heart failure or both
- Author
- Afeltra Antonella
- Agosti Pasquale
- Aiello Italia
- Alberto Jacopo
- Alcidi Riccardo
- Alessandro Montalto Filippo
- Alessandro Pulixi Edoardo
- Amoruso Emanuele
- Anastasio Luigi
- Angelucci Ermanno
- Antoci Valentina
- Antonella Galbussera Alessia
- Antonietta Bleve Maria
- Antonucci Cesare
- Ardoino Ilaria
- Argano Christiano
- Argiolas Giacomo
- Artoni Andrea
- Arturi Franco
- Baffa Bellucci Francesco
- Baldassarre Stefano
- Ballestrero Alberto
- Barbagallo Mario
- Bartelloni Giacomo
- Bartone Mosè
- Basile Giorgio
- Battaglia Rosa
- Beccati Valentina
- Bellan Mattia
- Bellelli Giuseppe
- Bellone Federica
- Beneduce Vincenza
- Benfaremo Devis
- Benzoni Ilaria
- Bernardi Mauro
- Berria Maria
- Berti Franco
- Bertolotti Marco
- Bertozzi Irene
- Bettiol Alessandra
- Bianconi Vanessa
- Bigi Elena
- Biolo Gianni
- Biondi Lorenzo
- Boari Benedetta
- Boccardi Virginia
- Bocchi Pietro
- Bogoni Giulia
- Bonfanti Alessandra
- Bonini Giulia
- Borghi Claudio
- Bozzolo Enrica
- Bragagni Alessio
- Brenna Martino
- Brucato Antonio
- Brunori Mattia
- Buffelli Stefano
- Busti Fabiana
- Busti Fabiana
- Cacioppo Federica
- Calipari Daniela
- Cambiè Ginevra
- Cammarosano Michela
- Campiotti Leonardo
- Capeci William
- Cappelli Silvia
- Carbone Maria
- Carulli Lucia
- Caruso Rossella
- Caserza Lara
- Castellino Pietro
- Castello Roberto
- Castiglioni Luana
- Catalano Antonino
- Catalano Claudia
- Cattaneo Federico
- Cattaneo Marco
- Cavallaro Federica
- Ceriani Giuliana
- Cerminara Domenico
- Cerruti Lorenzo
- Cesaroni Giulia
- Cespiati Annalisa
- Chiuch Massimiliano
- Cilli Mirella
- Cinque Felice
- Cipollone Francesco
- Ciro Canetta
- Clausi Elvira
- Clerici Marta
- Colangelo Lidia
- Colangelo Luciano
- Colombo Giulia
- Comitangelo Alessio
- Condoleo Valentino
- Cono Giulia
- Conti Federica
- Corica Francesco
- Corrao Salvatore
- Corrao Salvatore
- Corrao Salvatore
- Corsi Maurizio
- Corsi Maurizio
- Cosi Elisabetta
- Costanzo Giulia
- Crisafulli Ernesto
- Custodero Carlo
- Dal Col Anna
- Damanti Sarah
- Damiani Giampaolo
- Davide Diprizio Roberto
- De Amicis Margherita Migone
- De Falco Teresa
- De Luca Giacomo
- De Vincenzo Giovanni Michele
- Del Giacco Stefano
- del Vecchio Sara
- Delitala Alessandro
- Delitala Giuseppe
- Dell’Unto Chiara
- Dentali Francesco
- Di Marca Salvatore
- Di Mauro Alessandra Danuta
- Di Mauro Alessandra Danuto
- Di Meo Irene
- Di Pino Antonino
- Di Pino Antonino
- Di Quattro Rosario
- Di Sabatino Antonio
- Di Stefano Valeria
- Dionigi Rossi Paolo
- Dolenti Silvia
- Domenica Cappellini Maria
- Dominguez Ligia
- Dondi Giulia
- Durante Vittorio
- D’Aniano Salvatore
- D’Ardes Damiani
- D’Aurizio Gabriella
- Elena Pipita Maria
- Emmi Giacomo
- Esposito Lucia
- Eusebi Giovanna
- Fabio Giovanna
- Fabris Fabrizio
- Fabrizi Maddalena
- Falanga Lina
- Falbo Tania
- Falcetta Andrea
- Famularo Giuseppe
- Fasolino Cristina
- Favale Edoardo
- Fenoglio Luigi
- Ferrandina Camillo
- Ferrando Fabio
- Filice Marco
- Filippini Emanuele
- Firinu Davide
- Folli Christian
- Fondrieschi Luigi
- Fracanzani Anna L
- Fracasso Paola
- Fragapani Salvatore
- Franchi Carlotta
- Franchi Carlotta
- Franchi Carlotta
- Galassi Matteo
- Gallo Paolo
- Gandolfo Federica
- Gaudio Agostino
- Gennaro Alfio
- Ghio Riccardo
- Gino Miriam
- Gino Miriam
- Giofrè Federica
- Giorgi Alfredo
- Giorgi Antonella
- Giotta Alessia
- Girelli Domenico
- Girelli Domenico
- Giulia Leoni Francesca
- Giuseppe Maggio Marcello
- Gonella Roberta
- Gracin Christian
- Grassi Yasmine
- Grazia Serra Maria
- Graziella Bruno
- Greco Alessio
- Grignani Giulia
- Grossi Alessandra
- Grossi Margherita
- Gruden Gabriella
- Guasti Luigina
- Harari Sergio
- Ianniello Eugenia
- Imbimbo Giovanni
- Indiano Ilaria
- Kassem Salam
- La Malfa Lara
- Labbadia Giancarlo
- Laghi Pasini Franco
- Lancellotti Giulia
- Larovere Erica
- Laura Matacena Maria
- Lazzari Ilaria
- Leonardi Roberto
- Leoncini Giovanna
- Leoni Simona
- Leoni Simona
- LeopoldoCapecchi Pier
- Li Bassi Silvia
- Liberale Luca
- Licata Anna
- Lonati Chiara
- Loparco Francesca
- Lorenzo Squintani Giovanni
- Losa Francesca
- Lucchi Tiziano
- Lucente Daniela
- Lucio Liberato Nicola
- Luisa Randi Maria
- Lupattelli Graziana
- Magnolfi Eleonora
- Maio Raffaele
- Maira Diletta
- Malatino Lorenzo
- Mancarella Marta
- Mancuso Gerardo
- Manfredini Roberto
- Mannarino Massimo R.
- Mannucci Pier Mannuccio
- Mannuccio Mannucci Pier
- Mannuccio Mannucci Pier
- Manzoni Francesca
- Marchi Giacomo
- Marengoni Alessandra
- Marengoni Alessandra
- Marengoni Alessandra
- Maresca Andrea
- Margaria Carl
- Marigliano Benedetta
- Marta Viglione Giulia
- Martelengo Miriana
- Mattioli Irene
- Mattioli Massimo
- Mazzeo Francesca
- Mazzola Paolo
- Mecocci Patrizia
- Meschi Tiziana
- Mete Francesca
- Miceli Emanuela
- Miglio Gabriella
- Minisola Salvatore
- Minuz Pietro
- Molfino Alessio
- Monaco Lucio
- Montalto Giuseppe
- Montecucco Fabrizio
- Montrucchio Giuseppe
- Monzani Valter
- Morellini Sarah
- Moreo Guido
- Morganti Simonetta
- Moroncini Gianluca
- Mularo Salvatore
- Muscaritoli Maurizio
- Mussi Chiara
- Napoli Federico
- Natoli Giuseppe
- Negro Enrica
- Nicolini Paola
- NigroImperiale Giandomenico
- Nobili Alessandro
- Nobili Alessandro
- Nobili Giulia
- Nouvenne Antonio
- Novella Alessio
- Novella Alessio
- Novelli Marco
- Nuti Ranuccio
- Oberti Giovanna
- Orio Giuseppe
- Orlandi Laura
- Ormas Monica
- Ottonello Luciano
- Padula Donatella
- Pagliaro Erica
- Palazzuoli Alberto
- Pallini Giada
- Paoletti Giovanni
- Paolisso Giuseppe
- Paolo Fra Gian
- PaoloCeda Gian
- Pareo Ilenia
- Pasina Luca
- Pasina Luca
- Pasino Michela
- Peasso Paolo
- Pellegrini Elisa
- Perri Ludovica
- Perticone Francesco
- Perticone Francesco
- Perticone Maria
- Petrillo Enrico
- Pettinari Pietro
- Peyvandi Flora
- Piazzoli Andrea
- Picardi Antonio
- Pietrangelo Antonello
- Pietrangelo Antonello
- Pignataro Samuele
- Pilotto Alberto
- Pina Gloria
- Pio Martino Giuseppe
- Pirisi Mario
- Piro Salvatore
- Pirozzi Annalisa
- Pirro Matteo
- Pisati Martina
- Pitotti Lavinia
- Poletto Cesare
- Pontremoli Roberto
- Porta Massimo
- Prandini Tancredi
- Principato Concetto
- Principato Giulia
- Prisco Domenico
- Prolo Silvia
- Prolo Silvia
- Purrello Francesco
- Purrello Francesco
- Quadri Roberto
- Raspanti Massimo
- Ratti Francesco
- Re Giuseppe
- Ricozzi Carmen
- Rizzo Angelo
- Romanelli Giuseppe
- Romiti Roberto
- Rosaria Rizzo Maria
- Rossi Ilaria
- Rossio Raffaella
- Rotunno Francesca
- Rozzini Renzo
- Ruggeri Eugenio
- Ruggiero Carmelinda
- Ruvio Martina
- Sabbà Carlo
- Salerno Francesco
- Salvatore Teresa
- Salvi Andrea
- Sando Valeria
- Sanino Maura
- Santi Luca
- Sartori Giulia
- Savojardo Valeria
- Savriè Caterina
- Scaramellini Natalia
- Scarduelli Sara
- Scarsi Camilla
- Schiavone Silvia
- Schilardi Andrea
- Sciacqua Angela
- Scozzafava Aleandra
- Scurti Rosa
- Seghezzi Sonia
- Semproni Eleonora
- Serafini Giovanni
- Sesti Giorgio
- Sesti Giorgio
- Sestili Simona
- Setti Paolo
- Sidoli Chiara
- Sigon Giordano
- Silvestri Elena
- Simeone Emilio
- Simili Angelo
- Simili Angelo
- Sofia Lucia
- Sola Daniele
- Soldati Mario
- Spazzini Elena
- Squizzato Alessandro
- Stancanelli Benedetta
- Stanghellini Vincenzo
- Stella Pisciotta Maria
- Strocchi Enrico
- Succurro Elena
- Suppressa Patrizia
- Szabo Hajnalka
- Tarquini Roberto
- Tarsitani Patrizia
- Tassone Bruno
- Teresa Guagnano Maria
- Terranova Valentina
- Tettamanti Mauro
- Tettamanti Mauro
- Tettamanti Mauro
- Tettamanti Mauro
- Ticinesi Andrea
- Tiraboschi Silvia
- Tirotta Daniela
- Tiseo Ruana
- Tognin Tiziana
- Tolloso Fabio
- Traversa Chiara
- Tresoldi Moreno
- Trotta Lucia
- Valenti Roberto
- Valentina Amoruso Maria
- Valentina Giraudo Alessia
- Valeriani Emanuele
- Valoriani Alice
- Vannini Giulia
- Vanoli Massimo
- Vespasiani Gentilucci Umberto
- Vianello Alice
- Victoria Rabuini Maria
- Vigani Giulia
- Vignali Alessandro
- VincenzoLenti Marco
- Violi Francesco
- Violi Francesco
- Violi Francesco
- Vischi Giulia
- Vittoria Libbra Maria
- Volpi Riccardo
- Volpini Andrea
- Zaccari Michele
- Zaccherini Giacomo
- Zanetti Michela
- Zanoli Luca
- Zoli Marco
- Zuccalà Giuseppe
- Zucchelli Alberto
- Zurlo Chiara
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background and objective: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) mutually increase the risk of being present in the same patient, especially if older. Whether or not this coexistence may be associated with a worse prognosis is debated. Therefore, employing data derived from the REPOSI register, we evaluated the clinical features and outcomes in a population of elderly patients admitted to internal medicine wards and having COPD, HF or COPD + HF.
Methods: We measured socio-demographic and anthropometric characteristics, severity and prevalence of comorbidities, clinical and laboratory features during hospitalization, mood disorders, functional independence, drug prescriptions and discharge destination. The primary study outcome was the risk of death.
Results: We considered 2,343 elderly hospitalized patients (median age 81 years), of whom 1,154 (49%) had COPD, 813 (35%) HF, and 376 (16%) COPD + HF. Patients with COPD + HF had different characteristics than those with COPD or HF, such as a higher prevalence of previous hospitalizations, comorbidities (especially chronic kidney disease), higher respiratory rate at admission and number of prescribed drugs. Patients with COPD + HF (hazard ratio HR 1.74, 95% confidence intervals CI 1.16-2.61) and patients with dementia (HR 1.75, 95% CI 1.06-2.90) had a higher risk of death at one year. The Kaplan-Meier curves showed a higher mortality risk in the group of patients with COPD + HF for all causes (p = 0.010), respiratory causes (p = 0.006), cardiovascular causes (p = 0.046) and respiratory plus cardiovascular causes (p = 0.009).
Conclusion: In this real-life cohort of hospitalized elderly patients, the coexistence of COPD and HF significantly worsened prognosis at one year. This finding may help to better define the care needs of this population
Clinical features and outcomes of elderly hospitalised patients with chronic obstructive pulmonary disease, heart failure or both
- Author
- 13 Francesca Giulia Leoni
- Agostino Gaudio
- Alberto Balle- strero
- Alberto Palazzuoli (Azienda Ospedaliera Università Senese
- Alberto Pilotto
- Alberto Zucchelli (Unità Operativa Complessa di Medicina I a indirizzo geriatrico
- Aleandra Scozzafava
- Ales- sandra Grossi
- Ales- sio Molfino
- Alessandra Bettiol
- Alessandra Bonfanti
- Alessandra Danuta Di Mauro
- Alessandra Danuto Di Mauro
- Alessandra Marengoni
- Alessandro Delitala (Azienda ospedaliera- universitaria di Sassari
- Alessandro Squizzato
- Alessandro Vignali (Azienda Ospe- daliera Universitaria di Parma
- Alessia Giotta
- Alessia Valentina Giraudo
- Alessio Bragagni
- Alessio Comitangelo
- Alessio Greco
- Alfio Gennaro
- Alfredo De Giorgi
- Alice Valoriani
- Allergologia ed Immunologia Clinica)
- Andrea Artoni
- Andrea Falcetta
- Andrea Maresca
- Andrea Piazzoli
- Andrea Salvi
- Andrea Schilardi
- Andrea Ticinesi
- Andrea Volpini
- Angela Sciacqua
- Angelo Rizzo (Azienda Ospe- daliera Universitaria Policlinico Paolo Giaccone
- Angelo Simili
- Angelo Simili (Azienda Ospe- daliera Universitaria Policlinico S. Orsola-Malpighi
- Angiologia Malattie da Arteriosclerosi)
- Anna Dal Col (Azienda Ospedaliera Università San Martino
- Anna L. Fracanzani
- Anna Licata
- Annalisa Cespiati
- Annalisa Pirozzi
- Antonella Afeltra
- Antonella Giorgi
- Antonino Cata- lano
- Antonino Di Pino
- Antonino Di Pino (Ospedale GaribaldiNesima – Catania
- Antonio Brucato
- Antonio Di Sabatino
- Antonio Nouvenne (Azienda Ospedaliera Universitaria di Parma
- Antonio Picardi
- ASL TO4
- Azienda Ospedaliera Universitaria- Ospedali Riuniti di Ancona)
- Azienda Ospedaliera Università San Martino di Genova)
- Azienda Ospedaliero-Universitaria di Cagliari
- Azienda Ospedaliero-Universitaria di Modena
- Bari
- Benedetta Boari
- Benedetta Marigliano
- Benedetta Stancanelli
- Benfratelli Palermo
- Bologna
- Bologna
- Bologna
- Bologna)
- Brescia
- Bruno Graziella
- Bruno Tassone
- Busti Fabiana
- Cagliari
- Camilla Scarsi (Clinica Di Medicina Interna ad Indirizzo Oncologico
- Camillo Ferrandina
- Canetta Ciro
- Carl Margaria
- Carlo Custodero
- Carlo Sabbà
- Carmelinda Ruggiero
- Carmen Ricozzi (Policlinico Università della Campania L. Vanvitelli
- Cat- anzaro
- Catania
- Catania
- Catania
- Catanzaro
- Caterina Savriè (Azienda OspedalieraUniversitaria Sant'Anna
- Cesare Antonucci
- Cesare Poletto
- Chiara Dell’Unto (Università Campus Bio- Medico
- Chiara Lonati
- Chiara Mussi
- Chiara Sidoli
- Chiara Traversa
- Chiara Zurlo
- Chieti
- Christian Folli (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Christian Gracin
- Christiano Argano
- Città della Scienza e della Salute
- Claudia Catalano
- Claudio Borghi
- Clinica di Medicina Interna 2)
- Clinica e Terapia Medica)
- Clinica Medica 1
- Clinica Medica Generale e Terapia Medica)
- Clinica Medica I
- Clinica Medica I)
- Clinica Medica Università di Catania)
- Clinica Medica)
- Clinica Medica)
- Concetto Principato (Azienda Ospedaliera Universitaria Policlinico G. Martino
- Crisafulli Ernesto
- Cristina Fasolino (Azienda ospedaliera San Paolo
- Cuneo
- Damiani D’Ardes
- Daniela Calipari
- Daniela Lucente
- Daniela Tirotta
- Daniele Sola
- Davide Firinu
- Devis Benfaremo
- Di Cristina
- Diletta Maira
- Dipartimento di Medicina)
- Domenico Cerminara
- Domenico Girelli
- Domenico Investigators—Domenico Prisco
- Donatella Padula
- Edoardo Alessandro Pulixi (Azienda Ospedaliera della Pro- vincia di Lecco
- Edoardo Favale
- Elena Bigi
- Elena Silvestri
- Elena Spazzini
- Elena Succurro
- Eleonora Magnolfi
- Eleonora Semproni (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Elisa Pellegrini
- Elisabetta Cosi (Azienda Ospe- daliera Università di Padova
- Ema- nuele Amoruso
- Emanuela Miceli
- Emanuele Filippini
- Emanuele Valeriani
- Emato- logia non tumorale e Coagulopatie)
- Emilio Simeone
- Empoli
- Enrica 13 Internal and Emergency Medicine Internal and Emergency Medicine Bozzolo
- Enrica Negro
- Enrico Petrillo
- Enrico Strocchi
- Erica Larovere
- Erica Pagliaro
- Ermanno Angelucci (Ospedale Clinicizzato SS. Annunziata
- Eugenia Ianniello
- Eugenio Ruggeri
- Fabiana Busti
- Fabio Ferrando
- Fabio Tolloso (Ospedale Spirito Santo di Pescara
- Fabrizio Fabris
- Fabrizio Montecucco
- Federica Bellone
- Federica Cacioppo (Azienda Ospedaliera Universitaria Policlinico Giaccone Policlinico di Palermo
- Federica Cavallaro (A. R. N. A. S. Civico
- Federica Conti
- Federica Gandolfo (Ente Ospe- daliero Ospedali Galliera Genova
- Federica Giofrè (Università degli Studi Magna Grecia
- Federico Cattaneo (IRCCS Azienda Ospedaliera Universitaria San Martino-IST di Genova
- Federico Napoli
- Felice Cinque (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Ferrara
- Filippo Alessandro Montalto
- Firenze
- Flora Peyvandi
- Franc- esco Violi
- Francesca Loparco (Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
- Francesca Losa (Policlinico Universitario Duilio Casula
- Francesca Manzoni
- Francesca Mazzeo
- Francesca Mete
- Francesca Rotunno
- Francesco Baffa Bellucci
- Francesco Cipollone
- Francesco Corica
- Francesco Dentali (Università degli Studi dell'Insubria
- Francesco Purrello
- Francesco Purrello
- Francesco Ratti
- Francesco Salerno
- Francesco Saverio Vella
- Franco Arturi
- Franco Berti
- Gabriella D’Aurizio (Policlinico Universitario A. Gemelli
- Gabriella Gruden (Medicina Interna III
- Gen- ova
- Genova
- Genova
- Gerardo Mancuso
- Geriatria)
- Giacomo Argiolas
- Giacomo Bartelloni
- Giacomo De Luca
- Giacomo Emmi
- Giacomo Marchi (Azienda Ospedaliera Universitaria Integrata di Verona
- Giacomo Zaccherini (Azienda Ospe- daliera Policlinico Sant’Orsola-Malpighi
- Giada Pallini (IRCCS Policlinico San Donato e Università di Milano
- Giampaolo Damiani (Spedali Civili di Brescia
- Gian Paolo Fra
- Giancarlo Labbadia (Poli- clinico Umberto I
- Giandomen- ico Nigro Imperiale
- Gianluca Moroncini
- Gianni Biolo
- Ginevra Cambiè (IRCCS Policlinico San Matteo di Pavia
- Gio- vanna Fabio
- Gio- vanni Imbimbo (Policlinico Umberto I
- Giordano Sigon
- Giorgio Basile
- Giovanna Eusebi (Ospedale di Cattolica
- Giovanna Leoncini
- Giovanna Oberti
- Giovanni Lorenzo Squintani (ASST FatebenefratelliSacco
- Giovanni Michele De Vincenzo
- Giovanni Paoletti
- Giovanni Serafini
- Girelli
- Giulia Bogoni
- Giulia Bonini
- Giulia Cesaroni (Ospedale Poliambulanza
- Giulia Colombo
- Giulia Cono
- Giulia Costanzo
- Giulia Dondi
- Giulia Grignani
- Giulia Lancellotti
- Giulia Marta Viglione
- Giulia Nobili
- Giulia Principato
- Giulia Vannini (Ospedale San Giuseppe
- Giulia Vigani
- Giulia Vischi
- Giuliana Ceriani
- Giuseppe Bellelli
- Giuseppe Delitala
- Giuseppe Famularo
- Giuseppe Montalto
- Giuseppe Montrucchio
- Giuseppe Natoli
- Giuseppe Orio
- Giuseppe Paolisso
- Giuseppe Pio Martino
- Giuseppe Re
- Giuseppe Zuccalà
- Gloria Pina (Clinica San Carlo Casa di Cura Polispecialistica
- Graziana Lupattelli
- Hajnalka Szabo
- Ilaria Benzoni (Dipartimento di Scienze Mediche e Chirurgiche
- Ilaria Indiano
- Ilaria Lazzari
- Ilaria Rossi
- Ilenia Pareo (Azienda Ospedaliera Universitaria Poli- clinico S. Orsola-Malpighi
- Irene Bertozzi
- Irene Di Meo (Azienda Ospedaliera Universitaria della Seconda Università degli Studi di Napoli
- Irene Mattioli (Azienda Ospedaliero Universitaria Careggi Firenze
- Italia Aiello (Divisione di Medicina Interna
- Jacopo Alberto
- Lara Caserza
- Lara La Malfa
- Laura Orlandi
- Lavinia Pitotti
- Lecce
- Lecco
- Leonardo Campiotti
- Lidia Colangelo
- Ligia Dominguez
- Lina Falanga
- Lorenzo Biondi
- Lorenzo Cerruti
- Lorenzo Malatino
- Luana Castiglioni
- Luca Liberale (IRCCS Ospedale Policlinico San Martino e Università di Genova
- Luca Santi
- Luca Zanoli
- Lucia Carulli (Università di Modena e Reggio Emilia
- Lucia Esposito
- Lucia Sofia
- Lucia Trotta
- Luciano Colangelo
- Luciano Ottonello
- Lucio Monaco
- Ludovica Perri (Policlinico Umberto I
- Luigi Anastasio
- Luigi Fenoglio
- Luigi Fondrieschi
- Luigina Guasti
- Maddalena Fabrizi
- Mannucci Pier Mannuccio
- Marcello Giuseppe Maggio Gian Paolo Ceda
- Marco Bertolotti
- Marco Cattaneo
- Marco Filice Elvira Clausi (Università Geriatriche)
- Marco Novelli (Ospedale di Ciriè
- Marco Vincenzo Lenti
- Marco Zoli
- Margherita Grossi (Azienda Ospedaliero Uni- versitaria di Parma
- Margherita Migone De Amicis
- Maria Antonietta Bleve (Azienda Ospedaliera
- Maria Berria
- Maria Carbone (Ospedale Civile Jazzolino di Vibo Valentia
- Maria Domenica Cappellini
- Maria Elena Pipita (Policlinico Campus Biomedico Roma
- Maria Grazia Serra
- Maria Laura Mata- cena
- Maria Luisa Randi
- Maria Perticone
- Maria Rosaria Rizzo
- Maria Stella Pisciotta
- Maria Teresa Guag- nano
- Maria Valentina Amoruso
- Maria Victoria Rabuini
- Maria Vittoria Libbra
- Mario Barbagallo
- Mario Pirisi
- Mario Soldati
- Marta Clerici
- Marta Mancarella (Fon- dazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Martina Pisati
- Martina Ruvio
- Martino Brenna
- Massi- miliano Chiuch (Azienda Sanitaria Universitaria Integrata di Trieste
- Massimo Mattioli
- Massimo Porta
- Massimo R. Mannarino (Azienda Ospedaliera Santa Maria della Misericordia
- Massimo Raspanti
- Massimo Vanoli
- Matteo Galassi
- Matteo Pirro
- Mattia Bellan (Azienda Ospedaliera Universitaria Maggiore della Carità
- Mattia Brunori
- Maura Sanino (Dipartimento di Scienze Mediche
- Maurizio Corsi
- Maurizio Corsi (Università degli studi di Milano-Bicocca Ospedale S. Gerardo
- Maurizio Muscaritoli
- Mauro Ber- nardi
- Medicina Clinica)
- Medicina Clinica-Epatolo- gia)
- Medicina e Geriatria)
- Medicina Generale e delle Cure Avanzate)
- Medicina Generale e Malattie Aterotrombotiche e Degenerative)
- Medicina Generale e Sezione di Decisione Cli- nica)
- Medicina Generale per lo Studio ed il Trattamento dell’Ipertensione Arteriosa)
- Medicina Generale)
- Medicina III)
- Medicina III)
- Medicina Interna
- Medicina Interna
- Medicina Interna 1)
- Medicina Interna 1U).
- Medicina Interna 2
- Medicina Interna 2 Unità Indirizzo d'Urgenza)
- Medicina Interna Alta Intensità di Cure)
- Medicina Interna e Geriatria)
- Medicina Interna e Nutrizione Clinica Policlinico Umberto I)
- Medicina Interna e Specialità Mediche)
- Medicina Interna I)
- Medicina Interna I)
- Medicina Interna II)
- Medicina Interna Universitaria C. Frugoni)
- Medicina Interna)
- Medicina Interna)
- Medicina Interna)
- Medicina Interna)
- Medicina Interna)Guido Moreo
- Messina
- Michela Cammarosano
- Michela Pasino (Ospedale Civile Maggiore Borgo Trento
- Michela Zanetti
- Michele Zaccari
- Milano
- Milano
- Milano
- Milano
- Milano
- Milano
- Milano
- Milano Geriatria)
- Milano)
- Mirella Cilli
- Miriam Gino (AOU Città della Salute e della Scienza di Torino – Torino
- Miriam Gino (Ospedale degli Infermi di Rivoli
- Miriana Martelengo
- Monica Ormas
- Montichiari Brescia)
- Monza
- Moreno Tresoldi
- Mosè Bartone (Ospedale Giovanni Paolo II Lamezia Terme
- Multimedica IRCSS
- Napoli
- Nata- lia Scaramellini
- Nicola Lucio Liberato
- Nobili Alessandro
- Ortogeriatria e Riabilitazione)Franco Laghi Pasini
- Ospedale Civile di Baggiovara Unità Operativa di Geriatria)
- Ospedale di Casorate Primo
- Ospedale di Circolo e Fondazione Macchi
- Ospedale di Merate
- Ospedale S. Giovanni Battista Molinette
- Paderno Dugnano
- Padova
- Palermo
- Palermo
- Paola Fracasso
- Paola Nicolini (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
- Paolo Dionigi Rossi
- Paolo Gallo
- Paolo Mazzola
- Paolo Peasso
- Paolo Setti
- Pasquale Agosti
- Patrizia Mecocci
- Patrizia Sup- pressa
- Patrizia Tarsitani (Azienda Ospedaliera San Camillo Forlanini
- Pavia
- Pavia)
- Perugia
- Perugia
- Pier Leopoldo Capecchi (Azienda Ospedaliera Universitaria Senese
- Pietro Bocchi
- Pietro Castellino
- Pietro Minuz
- Pietro Pettinari
- Policlinico GB Rossi
- Policlinico Mater Domini
- Prima Clinica Medica)
- Raffaele Maio
- Raffaella Rossio
- Ranuccio Nuti
- Renzo Rozzini
- Reparto 11)
- Riccardo Alcidi
- Riccardo Ghio
- Riccardo Volpi
- Rimini
- Roberta Gonella
- Roberto Castello
- Roberto Davide Diprizio
- Roberto Leonardi
- Roberto Man- fredini
- Roberto Pontremoli
- Roberto Quadri
- Roberto Romiti (Clinica Medica
- Roberto Tar- quini
- Roberto Val- enti
- Roma
- Roma
- Roma
- Roma
- Roma
- Roma Roma
- Rosa Battaglia
- Rosa Scurti
- Rosario Di Quattro
- Rossella Caruso (Azienda Ospedaliera per l'Emergenza Cannizzaro
- Ruana Tiseo
- S. C. Medicina Interna)
- S. C. Medicina Interna)
- Salam Kassem
- Salvatore Corrao
- Salvatore Di Marca
- Salvatore D’Aniano (Azienda Sanitaria Ospedaliera Santa Croce e Carle di Cuneo
- Salvatore Fragapani
- Salvatore Minisola
- Salvatore Mularo
- Salvatore Piro (Ospedale Garibaldi Nesima
- Samuele Pignataro (Azienda Ospedaliera Universitaria Poli- clinico – V. Emanuele
- San Donato Milanese
- Sapienza Università di Roma
- Sara del Vec- chio
- Sara Scarduelli
- Sarah Damanti (IRCCS Ospedale San Raffaele – Milano
- Sarah Morellini (Azienda Ospedaliera Universi- taria Verona
- Sartori Giulia
- SC Geriatria Dipartimento Cure Geriatriche
- Semeiotica Medica Bernardi)
- Sergio Harari
- Siena
- Siena
- Silvia Cappelli
- Silvia Dolenti
- Silvia Li Bassi
- Silvia Prolo
- Silvia Prolo
- Silvia Schiavone
- Silvia Tiraboschi
- Simona Leoni
- Simona Leoni
- Simona Sestili
- Simonetta Mor- ganti
- SMSC03Medicina Interna F e Malattie Meta- boliche dell'osso)
- SOD Medicina Interna Interdisciplinare)
- Sonia Seghezzi
- Spedali Civili
- Stefano Baldassarre
- Stefano Buf- felli
- Stefano Del Giacco
- Struttura Complessa di Geriatria)
- Tancredi Prandini
- Tania Falbo
- Teresa De Falco
- Teresa Salvatore
- Tiziana Meschi
- Tiziana Tognin (ASST di Pavia
- Tiziano Lucchi
- Torino
- Torino
- Torino
- Torino)
- U. O Medicina Interna e Lungodegenza Critica)
- U. O. 3a Medicina Generale)
- U. O. C Clinica Geriatrica)
- U. O. C Medicina Interna)
- Umberto Vespasiani Gentilucci
- Unità Operativa Clinica Medica)
- Unità Operativa Complessa di Medicina Interna)
- Unità Operativa Complessa di Medicina Interna)
- Unità Operativa Complessa Medicina 2)
- Unità Operativa Complessa Medicina d'Urgenza e Pronto Soccorso)Giuseppe Romanelli
- Unità Operativa Complessa Medicina Interna)
- Unità Operativa Complessa Medicina)
- Unità Operativa di Geri- atria)
- Unità Operativa di Geri- atria)
- Unità Operativa di Geriatria e Lun- godegenza)
- Unità Operativa di Medicina Generale Emilio Bernardelli)
- Unità Operativa di Medicina Interna
- Unità Operativa di Medicina Interna Borghi)
- Unità Operativa di Medicina Interna Zoli)
- Unità Operativa Medicina Interna IA)
- Università degli Studi di Bologna/ Azienda Ospedaliero- Universitaria S. Orsola-Malpighi
- Università di Torino
- UOC di Medicina Interna)
- UOC Medicina Generale ad Indirizzo Metabolico)
- UOC Medicina Interna ad Indirizzo Geriatrico- Riabilitativo)
- UOC Medicina Interna)
- UOSD Medicina Interna
- USL Toscana Centro
- Valentina Antoci
- Valentina Beccati
- Valentina Terranova
- Valentino Condoleo
- Valeria De Sando
- Valeria Di Stefano
- Valeria Savojardo
- Valter Monzani
- Vanessa Bianconi
- Varese
- Verona
- Verona
- Verona
- VI Divisione di Medicina Interna e Malattie Nutrizionali dell'Invecchiamento)
- Vianello Alice
- Vibo Val- entia
- Vincenza Beneduce
- Vincenzo Stanghellini
- Virginia Boccardi (Università degli Studi di Perugia-Azienda Ospedaliera S. M. della Misericordia
- Vittorio Durante
- William Capeci
- Yasmine Grassi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2023
- Field of study
Background and objective: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) mutually increase the risk of being present in the same patient, especially if older. Whether or not this coexistence may be associated with a worse prognosis is debated. Therefore, employing data derived from the REPOSI register, we evaluated the clinical features and outcomes in a population of elderly patients admitted to internal medicine wards and having COPD, HF or COPD + HF. Methods: We measured socio-demographic and anthropometric characteristics, severity and prevalence of comorbidities, clinical and laboratory features during hospitalization, mood disorders, functional independence, drug prescriptions and discharge destination. The primary study outcome was the risk of death. Results: We considered 2,343 elderly hospitalized patients (median age 81 years), of whom 1,154 (49%) had COPD, 813 (35%) HF, and 376 (16%) COPD + HF. Patients with COPD + HF had different characteristics than those with COPD or HF, such as a higher prevalence of previous hospitalizations, comorbidities (especially chronic kidney disease), higher respiratory rate at admission and number of prescribed drugs. Patients with COPD + HF (hazard ratio HR 1.74, 95% confidence intervals CI 1.16-2.61) and patients with dementia (HR 1.75, 95% CI 1.06-2.90) had a higher risk of death at one year. The Kaplan-Meier curves showed a higher mortality risk in the group of patients with COPD + HF for all causes (p = 0.010), respiratory causes (p = 0.006), cardiovascular causes (p = 0.046) and respiratory plus cardiovascular causes (p = 0.009). Conclusion: In this real-life cohort of hospitalized elderly patients, the coexistence of COPD and HF significantly worsened prognosis at one year. This finding may help to better define the care needs of this population
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy
- Author
- A Kaldun Nossuli
- Aamir Jamal
- Adalbert Schiller
- Adam Cheifetz
- Adarsh Daswani
- Adeera Levin
- Adline Ghazi
- Adrian Guinsburg
- Adriana Cif
- Adriana Gabriela Onaca
- Adriana Ilavska
- Adriana Villarino
- Agarwal R.
- Agnieszka Starzec
- Ahmed Arif
- Ahmed Awad
- Aiping Yin
- Akimichi Asano
- Alan Jackson
- Alan McMahon
- Alan Perlman
- Alberto Di Carlo
- Alberto Esquenazi
- Alejandra Oviedo
- Alejandro Valdes Depeda
- Aleksandra Kendereski
- Alex Valenzuela
- Alexander Dreval
- Alexander Gonzalez
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- Souhila Ounadjela
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- Srikanth Bellary
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- Steven Fishbane
- Stuart Handelsman
- Suely Keiko Kohara
- Sun Kim
- Sun-Hee Park
- Sunil Sheth
- Susumu Kashine
- Svetlana Goykhman
- Svitlana D Bilyk
- Swee Win Lam
- Sylvia Rosas
- Sylvia Shaw
- Szilard Vasas
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- Sérgio Yamada
- Tadashi Iitsuka
- Takamoto Kodera
- Takashi Wada
- Takayuki Watanabe
- Tamara Malek Marin
- Tamas Oroszlan
- Tara Chang
- Tareq Nassar
- Tarissa Beatrice Zanata Petry
- Tatiana Koroleva
- Tatiana Morugova
- Tatiana Raskina
- Tatyana Zykova
- Te-Lin Hsia
- Terue Sakakibara
- Tetiana Zlova
- Tetsuji Niiya
- Tetyana Pertseva
- Tiago Schuch
- Timothy Hall
- Tom Christensen
- Tom Greene
- Tomas Drasnar
- Tomas Smith Casabella
- Tonatiu Diaz Escalante
- Toshihiko Yanase
- Toshio Kawada
- Vadym Vizir
- Vanassa Ratnasingam
- Venessa Tsang
- Venkata Behara
- Vera Klokocnikova
- Vera Krane
- Veronica Anghel
- Veselka Genadieva
- Vesna Popovic-Radinovic
- Viacheslav Marasaev
- Victor Commendatore
- Victor Saavedra Gajardo
- Vijayaraman Arutchelvam
- Viktor Margaritov
- Viktor Zaviriukha
- Viktoria Andreeva
- Vimladhevi Govender
- Vincent Pichette
- Vincent Woo
- Vira Tseluyko
- Virginia Esther Visco
- Vivek Sood
- Vivekan Jha
- Vladimir Dobronravov
- Vladimir Khirmanov
- Vladimir Tesar
- Vlado Perkovic
- Volker Burst
- Volodymyr Botsyurko
- Walter Guillermo Douthat
- Walter Pharr
- Wasim Hanif
- Wataru Yumita
- Wayne H-H Sheu
- Wayne Turner
- Wei Yen Kong
- Weihong Song
- Weiping Lu
- Wendy Lane
- Wenge Li
- Wheeler D. C.
- Wladmir Saporito
- Xuemei Li
- Xueqing Yu
- Yamil Canaan
- Yan Ren
- Yannick Le Meur
- Yaozhong Kong
- Yasuro Kumeda
- Yasushi Wakida
- Yavin Y.
- Yeong Hoon Kim
- Yevgeniya Svyshchenko
- Young Min Cho
- Yulia Samoylova
- Yung-Chuan Lu
- Yuriy Mostovoy
- Yuriy Shwartz
- Yvette Ethel Yap
- Zaynab Abejuela
- Zdravko Kamenov
- Zeid Khitan
- Zhang H.
- Zinman B.
- Zishan Ali
- Zuzana Ochodnicka
- Ângela Regina Nazario Sabbag
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2019
- Field of study
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
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- de Trocóniz Jorge F
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- Hatakeyama Kenichi
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- Heath Helen F
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- Hoehle Felix
- Hoepfner Kerstin
- Hoffmann Malte
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- Hohlmann Marcus
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- Holzner André
- Hong Byung-Sik
- Hoorani Hafeez R
- Horisberger Roland
- Hortiangtham Apichart
- Horvath Dezso
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- Juodagalvis Andrius
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- Yang Yong
- Yang Yu Chul
- Yates Brent
- Yazgan Efe
- Yelton John
- Yetkin Elif Asli
- Yetkin Taylan
- Yi Kai
- Yilmaz Yetkin
- Yohay Rachel
- Yonamine Ryo
- Yoo Hwi Dong
- Yoo Jaehyeok
- You Can
- Yu Geum Bong
- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabel James
- Zabi Alexandre
- Zaganidis Nicolas
- Zagoździńska Agnieszka
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenoni Florian
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhao Jingzhou
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zientek Margaret
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Sunan Kalijaga State Islamic University
- Publication date
- 01/01/2012
- Field of study
Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis
Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Abu Zeid Shimaa
- Ackert Andrew
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Jordon Rowe
- Adams Mark Raymond
- Adams Todd
- Adiguzel Aytul
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahmed Ijaz
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alimena Juliette
- Alunni Solestizi Luisa
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Anderson Ian
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Anelli Christopher
- Antonelli Louis
- Antropov Iurii
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asilar Ece
- Asin Ivan
- Askew Andrew
- Assran Yasser
- Ata Metin
- Ata Metin
- Attikis Alexandros
- Aubin Alexandre
- Auffray Etiennette
- Autermann Christian Tobias
- Autermann Christian Tobias
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M.
- Baber Mark
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- Wickramage Nadeesha
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- Xu Zijun
- Yagil Avraham
- Yalvac Metin
- Yang Mingming
- Yang Yong
- Yates Brent
- Yazgan Efe
- Yelton John
- Yetkin Elif Asli
- Yetkin Taylan
- Yi Kai
- Yilmaz Yetkin
- Yohay Rachel
- Yonamine Ryo
- Yoo Hwi Dong
- Yoo Jaehyeok
- You Can
- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabel James
- Zabi Alexandre
- Zaganidis Nicolas
- Zagozdzinska Agnieszka
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenoni Florian
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Jinzhong
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukov Valery
- Zhukova Victoria
- Zolkapli Zukhaimira
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV
An embedding technique to determine ττ backgrounds in proton-proton collision data
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Abercrombie Daniel
- Acharya Himal
- Ackert Andrew
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agaras Merve Nazlim
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad, 1
- Ahmad Muhammad, 2
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Al-bataineh Ayman
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Allen Brandon
- Almond John
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antonelli Louis
- Antropov Iurii
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arndt Till
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asghar Muhammad Irfan
- Asilar Ece
- Askew Andrew
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avila Carlos
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Bagliesi Giuseppe
- Bahinipati Seema
- Baidali Sergei
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Ball Austin
- Ball Fionn
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Barnyakov Alexander
- Baron Owen
- Barone Luciano
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- Bartek Rachel
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- Beghin Diego
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- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Beirão Da Cruz E Silva Cristóvão
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Belyaev Alexander
- Belyaev Andrey
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- Brivio Francesco
- Brochero Cifuentes Javier Andres
- Brom Jean-Marie
- Brommer S.
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- de Barbaro Pawel
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- De Lentdecker Gilles
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- De Palma Mauro
- De Roeck Albert
- de Trocóniz Jorge F
- De Wit Adinda
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- Yetkin Elif Asli
- Yohay Rachel
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- Yuan Li
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabi Alexandre
- Zaganidis Nicolas
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
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- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zeinali Maryam
- Zenaiev Oleksandr
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Aobo
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Zhicai
- Zhao Jingzhou
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Zientek Margaret
- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2019
- Field of study
An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).Peer reviewe
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