A transformação digital nas Forças Armadas Portuguesas

A Transformação Digital (TD) é uma mudança complexa e radical, um processo disruptivo que altera profundamente a forma como as organizações competem, interagem e criam valor. A OTAN, em junho de 2023, planeia aprovar a estratégia de TD a implementar até 2030. A União Europeia e a Administração Pública Portuguesa também estão empenhadas no digital. Estarão as Forças Armadas Portuguesas alinhadas com esta transformação? Qual a situação da sua TD? Para desenvolver esta investigação adotou-se uma metodologia assente num processo de raciocínio dedutivo, recorrendo a uma estratégia mista qualitativa e quantitativa, baseada no estudo de caso. A investigação começou por identificar os Digital Leaders da Aliança (Canadá, França, Noruega, Reino de Espanha, EUA, Finlândia e Reino Unido), os princípios orientadores para a TD e um modelo orientador para a mudança. Depois averiguou-se a situação das Forças Armadas Portuguesas, verificando-se que têm orientações para a inovação e para a transição digital, mas estão num patamar de maturidade digital inicial (digitalmente conscientes). O trabalho termina com a apresentação de contributos para a TD das Forças Armadas Portuguesas. Uma transformação que deverá ser impulsionada pela inovação e por novos modelos organizacionais, alimentados por uma força de trabalho digital ágil, adaptável e tecnologicamente eficiente.Digital Transformation (DT) is a complex and disruptive process that profoundly changes the way companies and organizations compete, interact, and create value. In June 2023, NATO will approve an implementation strategy to be deployed until 2030. The European Union and the Portuguese Public Administration are also committed to digital. Are the Portuguese Armed Forces aligned with such transformation? What is the status of their DT? To develop this research, the adopted methodology was based on a deductive reasoning process, using a mixed qualitative and quantitative strategy, based on the case study method. The research began by identifying the Alliance Digital Leaders (Canada, France, Norway, King of Spain, USA., Finland, and UK), the guiding principles for DT and a guiding model for change. Then, the situation of the Portuguese Armed Forces was investigated, verifying that they have guidelines for innovation and digital transition, but are at an early stage in what digital maturity concerns (digitally aware). The work ends with the presentation of contributions for an action plan regarding a DT for Portuguese Armed Forces, which should be driven by innovation and new business and operational models, powered by an agile, adaptable, and technologically efficient digital workforce.N/

Influência do género, da família e dos serviços de psicologia e orientação na tomada de decisão de carreira

Neste estudo analisa-se a infl uência do género, da família e dos Serviços de Orientação Vocacional na decisão de carreira. Participaram deste estudo 1930 alunos do 10º ao 12º anos, de escolas portuguesas, respondendo ao Questionário de Difi culdades de Tomada de Decisão e a outro de recolha de dados escolares e familiares. Mais de metade apresenta indecisão vocacional. Os resultados indicam uma infl uência positiva da família na tomada de decisão, e da Orientação Vocacional na prontidão da decisão. Os rapazes consideram a orientação vocacional mais útil, apresentam maior confi ança mas menos prontidão na decisão, recorrem menos aos pais, familiares e amigos, sendo mais infl uenciáveis. As raparigas apresentam-se mais inseguras e menos informadas. A partir dos resultados, apresentam-se recomendações para as práticas de orientação vocacional

Dissolvable Carboxymethylcellulose Microneedles for Noninvasive and Rapid Administration of Diclofenac Sodium

The aim of this study is to prepare dissolvable biopolymeric microneedle (MN) patches composed solely of sodium carboxymethylcellulose (CMC), a water-soluble cellulose derivative with good film-forming ability, by micromolding technology for the transdermal delivery of diclofenac sodium salt (DCF). The MNs with ≈456 µm in height displayed adequate morphology, thermal stability up to 200 °C, and the required mechanical strength for skin insertion (>0.15 N needle−1). Experiments in ex vivo abdominal human skin demonstrate the insertion capability of the CMC_DCF MNs up to 401 µm in depth. The dissolution of the patches in saline buffer results in a maximum cumulative release of 98% of diclofenac after 40 min, and insertion in a skin simulant reveals that all MNs completely dissolve within 10 min. Moreover, the MN patches are noncytotoxic toward human keratinocytes. These results suggest that the MN patches produced with CMC are promising biopolymeric systems for the rapid administration of DCF in a minimally invasive manner.publishe

Pullulan microneedle patches for the efficient transdermal administration of insulin envisioning diabetes treatment

The present study reports the fabrication of dissolvable microneedle (MN) patches using pullulan (PL), a water-soluble polysaccharide with excellent film-forming ability, for the transdermal administration of insulin, envisioning the non-invasive treatment of diabetes. PL MNs patches were successfully prepared by micromoulding and revealed good thermal stability (Tdmax = 294 °C) and mechanical properties (>0.15 N needle-1), penetrating skin up to 381 μm depth, as revealed by in vitro skin tests. After application into human abdominal skin in vitro, the MNs dissolved within 2 h releasing up to 87% of insulin. When stored at 4, 20 and 40 °C for 4 weeks, insulin was able to retain its secondary structure, as shown by circular dichroism spectropolarimetry. The prepared PL MNs were non-cytotoxic towards human keratinocytes, being suitable for skin application. These findings suggest that PL MNs have potential to deliver insulin transdermally, thus avoiding its subcutaneous administration.publishe

Search for diboson resonances in hadronic final states in 139 fb −1 of pp collisions at s = 13 TeV with the ATLAS detector

Abstract: Narrow resonances decaying into W W, W Z or ZZ boson pairs are searched for in 139 fb−1 of proton-proton collision data at a centre-of-mass energy of s = 13 TeV recorded with the ATLAS detector at the Large Hadron Collider from 2015 to 2018. The diboson system is reconstructed using pairs of high transverse momentum, large-radius jets. These jets are built from a combination of calorimeter- and tracker-inputs compatible with the hadronic decay of a boosted W or Z boson, using jet mass and substructure properties. The search is performed for diboson resonances with masses greater than 1.3 TeV. No significant deviations from the background expectations are observed. Exclusion limits at the 95% confidence level are set on the production cross-section times branching ratio into dibosons for resonances in a range of theories beyond the Standard Model, with the highest excluded mass of a new gauge boson at 3.8 TeV in the context of mass-degenerate resonances that couple predominantly to gauge bosons

Measurement of the azimuthal anisotropy of charged-particle production in Xe+Xe collisions at sNN =5.44 TeV with the ATLAS detector

This paper describes the measurements of flow harmonics v2-v6 in 3μb-1 of Xe+Xe collisions at sNN=5.44 TeV performed using the ATLAS detector at the Large Hadron Collider (LHC). Measurements of the centrality, multiplicity, and pT dependence of the vn obtained using two-particle correlations and the scalar product technique are presented. The measurements are also performed using a template-fit procedure, which was developed to remove nonflow correlations in small collision systems. This nonflow removal is shown to have a significant influence on the measured vn at high pT, especially in peripheral events. Comparisons of the measured vn with measurements in Pb+Pb collisions and p+Pb collisions at sNN=5.02 TeV are also presented. The vn values in Xe+Xe collisions are observed to be larger than those in Pb+Pb collisions for n=2, 3, and 4 in the most central events. However, with decreasing centrality or increasing harmonic order n, the vn values in Xe+Xe collisions become smaller than those in Pb+Pb collisions. The vn in Xe+Xe and Pb+Pb collisions are also compared as a function of the mean number of participating nucleons, (Npart), and the measured charged-particle multiplicity in the detector. The v3 values in Xe+Xe and Pb+Pb collisions are observed to be similar at the same (Npart) or multiplicity, but the other harmonics are significantly different. The ratios of the measured vn in Xe+Xe and Pb+Pb collisions, as a function of centrality, are also compared to theoretical calculations

Measurement of hadronic event shapes in high-p T multijet final states at √s = 13 TeV with the ATLAS detector

A measurement of event-shape variables in proton-proton collisions at large momentum transfer is presented using data collected at s = 13 TeV with the ATLAS detector at the Large Hadron Collider. Six event-shape variables calculated using hadronic jets are studied in inclusive multijet events using data corresponding to an integrated luminosity of 139 fb−1. Measurements are performed in bins of jet multiplicity and in different ranges of the scalar sum of the transverse momenta of the two leading jets, reaching scales beyond 2 TeV. These measurements are compared with predictions from Monte Carlo event generators containing leading-order or next-to-leading order matrix elements matched to parton showers simulated to leading-logarithm accuracy. At low jet multiplicities, shape discrepancies between the measurements and the Monte Carlo predictions are observed. At high jet multiplicities, the shapes are better described but discrepancies in the normalisation are observed. [Figure not available: see fulltext.

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake