107 research outputs found
The Topographic Signature of Ecosystem Climate Sensitivity in the Western United States
- Author
- Publication venue
- ScholarWorks at University of Montana
- Publication date
- 01/12/2019
- Field of study
It has been suggested that hillslope topography can produce hydrologic refugia, sites where ecosystem productivity is relatively insensitive to climate variation. However, the ecological impacts and spatial distribution of these sites are poorly resolved across gradients in climate. We quantified the response of ecosystem net primary productivity to changes in the annual climatic water balance for 30 years using pixel‐specific linear regression (30‐m resolution) across the western United States. The standardized slopes of these models represent ecosystem climate sensitivity and provide a means to identify drought‐resistant ecosystems. Productive and resistant ecosystems were most frequent in convergent hillslope positions, especially in semiarid climates. Ecosystems in divergent positions were moderately resistant to climate variability, but less productive relative to convergent positions. This topographic effect was significantly dampened in hygric and xeric climates. In aggregate, spatial patterns of ecosystem sensitivity can be implemented for regional planning to maximize conservation in landscapes more resistant to perturbations
The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe
- Author
- Adams Corey
- Adams David
- Akiri Tarek
- Alion Tyler
- Anderson Kris
- Andreopoulos Costas
- Andrews Mike
- Anghel Ioana
- Anjos João Carlos Costa dos
- Antonello Maddalena
- Arrieta-Diaz Enrique
- Artuso Marina
- Asaadi Jonathan
- Bai Xinhua
- Baibussinov Bagdat
- Baird Michael
- Balantekin Baha
- Baller Bruce
- Baptista Brian
- Barker D'Ann
- Barker Gary
- Barletta William A.
- Barr Giles
- Bartoszek Larry
- Bashyal Amit
- Bass Matt
- Bellini Vincenzo
- Benetti Pietro Angelo
- Berger Bruce E.
- Bergevin Marc
- Berman Eileen
- Berns Hans-Gerd
- Bernstein Adam
- Bernstein Robert
- Bhandari Babu
- Bhatnagar Vipin
- Bhuyan Bipul
- Bian Jianming
- Bishai Mary
- Blake Andrew
- Blaszczyk Flor
- Blaufuss Erik
- Bleakley Bruce
- Blucher Edward
- Blusk Steve
- Bocean Virgil
- Boffelli F.
- Boissevain Jan
- Bolton Timothy
- Bonesini Maurizio
- Boyd Steve
- Brandt Andrew
- Breedon Richard
- Bromberg Carl
- Brown Ralph
- Brunetti Giullia
- Buchanan Norman
- Bugg Bill
- Busenitz Jerome
- Calligarich E.
- Camilleri Leslie
- Carminati Giada
- Carr Rachel
- Castromonte Cesar
- Cavanna Flavio
- Centro Sandro
- Chen Alex
- Chen Hucheng
- Chen Kai
- Cherdack Daniel
- Chi Cheng-Yi
- Childress Sam
- Choudhary Brajesh Chandra
- Christodoulou Georgios
- Christofferson Cabot-Ann
- Church Eric
- Cline David
- Coan Thomas
- Cocco Alfredo
- Coelho Joao
- Coleman Stephen
- Conrad Janet M.
- Convery Mark
- Corey Robert
- Corwin Luke
- Cranshaw Jack
- Cronin-Hennessy Daniel
- Curioni A.
- da Motta Helio
- Davenne Tristan
- Davies Gavin S.
- Dazeley Steven
- de Geronimo Gianluigi
- de Gouvea Andre
- de Jong Jeffrey K.
- De Kaushik
- Demuth David
- Densham Chris
- Diwan Milind
- Djurcic Zelimir
- Dolfini R.
- Dolph Jeffrey
- Drake Gary
- Dye Stephen
- Dyuang Hongue
- Edmunds Daniel
- Elliott Steven
- Elnimr Muhammad
- Eno Sarah
- Enomoto Sanshiro
- Escobar Carlos O.
- Evans Justin
- Falcone A.
- Falk Lisa
- Farbin Amir
- Farnese Christian
- Fava Angela
- Felde John
- Fernandes S.
- Ferroni Fernando
- Feyzi Farshid
- Fields Laura
- Finch Alex
- Fitton Mike
- Fleming Bonnie
- Fowler Jack
- Fox Walt
- Friedland Alex
- Fuess Stu
- Fujikawa Brian
- Gallagher Hugh
- Gandhi Raj
- Garvey Gerald
- Gehman Victor M.
- Gibin Daniele
- Gill Ronald
- Gomes Ricardo A.
- Goodman Maury C.
- Goon Jason
- Graf Nicholas
- Graham Mathew
- Gran Rik
- Grant Christopher
- Grant Nick
- Greenlee Herbert
- Greenler Leland
- Grullon Sean
- Guardincerri Elena
- Guarino Victor
- Guarnaccia Evan
- Guedes Germano
- Guenette Roxanne
- Guglielmi Alberto
- Guzzo Marcelo M.
- Habig Alec T.
- Hackenburg Robert W.
- Hadavand Haleh
- Hahn Alan
- Haigh Martin
- Haines Todd
- Handler Thomas
- Hans Sunej
- Hartnell Jeff
- Harton John
- Hatcher Robert
- Hatzikoutelis Athans
- Hays Steven
- Hazen Eric
- Headley Mike
- Heavey Anne
- Heeger Karsten
- Heise Jaret
- Hellauer Robert
- Hewes Jeremy
- Himmel Alexander
- Hogan Matthew
- Holanda Pedro
- Holin Anna
- Horton-Smith Glenn
- Howell Joe
- Hurh Patrick
- Huston Joey
- Hylen James
- Imlay Richard
- Insler Jonathan
- Introzzi G.
- Isvan Zeynep
- Jackson Chris
- Jacobsen John
- Jaffe David E.
- James Cat
- Jen Chun-Min
- Johnson Marvin
- Johnson Randy
- Johnson Robert
- Johnson Scott
- Johnston William
- Johnstone John
- Jones Ben J. P.
- Jostlein H.
- Junk Thomas
- Kadel Richard
- Kaess Karl
- Karagiorgi Georgia
- Kaspar Jarek
- Katori Teppei
- Kayser Boris
- Kearns Edward
- Keener Paul
- Kemp Ernesto
- Kettell Steve H.
- Kirby Mike
- Klein Joshua
- Koizumi Gordon
- Kopp Sacha
- Kormos Laura
- Kropp William
- Kudryavtsev Vitaly A.
- Kumar Ashok
- Kumar Jason
- Kutter Thomas
- La Zia Franco
- Lande Kenneth
- Lane Charles
- Lang Karol
- Lanni Francesco
- Lanza Richard
- Latorre Tony
- LBNE Collaboration
- Learned John
- Lee David
- Lee Kevin
- Li Qizhong
- Li Shaorui
- Li Yichen
- Li Zepeng
- Libo Jiang
- Linden Steve
- Ling Jiajie
- Link Jonathan
- Littenberg Laurence
- Liu Hu
- Liu Qiuguang
- Liu Tiankuan
- Losecco John
- Louis William
- Lundberg Byron
- Lundin Tracy
- Lundy Jay
- Machado Ana Amelia
- Maesano Cara
- Magill Steve
- Mahler George
- Malon David
- Malys Stephen
- Mammoliti Francesco
- Mandal Samit Kumar
- Mann Anthony
- Mantsch Paul
- Marchionni Alberto
- Marciano William
- Mariani Camillo
- Maricic Jelena
- Marino Alysia
- Marshak Marvin
- Marshall John
- Matsuno Shiegenobu
- Mauger Christopher
- Mavrokoridis Konstantinos
- Mayer Nate
- McCauley Neil
- McCluskey Elaine
- McDonald Kirk
- McFarland Kevin
- McKee David
- McKeown Robert
- McTaggart Robert
- Mehdiyev Rashid
- Mei Dongming
- Menegolli A.
- Meng Guang
- Meng Yixiong
- Mertins David
- Messier Mark
- Metcalf William
- Milincic Radovan
- Miller William
- Mills Geoff
- Mishra Sanjib R.
- Mokhov Nikolai
- Montanari Claudio
- Montanari David
- Moore Craig
- Morfin Jorge
- Morgan Ben
- Morse William
- Moss Zander
- Moura Célio A.
- Mufson Stuart
- Muller David
- Musser Jim
- Naples Donna
- Napolitano Jim
- Newcomer Mitch
- Nichol Ryan
- Nicholls Tim
- Niner Evan
- Norris Barry
- Nowak Jaroslaw
- O'Keeffe Helen
- Oliveira Roberto
- Olson Travis
- Page Brian
- Pakvasa Sandip
- Palamara Ornella
- Paley Jon
- Paolone Vittorio
- Papadimitriou Vaia
- Park Seongtae
- Parsa Zohreh
- Partyka Kinga
- Paulos Bob
- Pavlovic Zarko
- Peeters Simon
- Perch Andy
- Perkin Jon D.
- Petti Roberto
- Petukhov Andre
- Pietropaolo Francesco
- Plunkett Robert
- Polly Chris
- Pordes Stephen
- Potekhin Maxim
- Potenza Renato
- Prakash Arati
- Prokofiev Oleg
- Qian Xin
- Raaf Jennifer L.
- Radeka Veljko
- Rakhno Igor
- Ramachers Yorck
- Rameika Regina
- Ramsey John
- Rappoldi A.
- Raselli G. L.
- Ratoff Peter
- Ravindra Shreyas
- Rebel Brian
- Reichenbacher Juergen
- Reitzner Dianne
- Rescia Sergio
- Richardson Martin
- Rielage Kieth
- Riesselmann Kurt
- Robinson Matt
- Rochester Leon
- Ronquest Michael
- Rosen Marc
- Rossella M.
- Rubbia Carlo
- Rucinski Russ
- Sahijpal Sandeep
- Sahoo Himansu
- Sala Paola
- Salmiera Delia
- Samios Nicholas
- Sanchez Mayly
- Scaramelli Alberto
- Schellman Heidi
- Schmitt Richard
- Schmitz David
- Schneps Jack
- Scholberg Kate
- Segreto Ettore
- Seibert Stanley
- Sexton-Kennedy Liz
- Shaevitz Mike
- Shanahan Peter
- Sharma Rahul
- Shaw Terri
- Simos Nikolaos
- Singh Venktesh
- Sinnis Gus
- Sippach William
- Skwarnicki Tomasz
- Smy Michael
- Sobel Henry
- Soderberg Mitch
- Sondericker John
- Sondheim Walter
- Sousa Alexandre
- Spooner Neil J. C.
- Stancari Michelle
- Stancu Ion
- Stefan Dorota
- Stefanik Andy
- Stewart James
- Stone Sheldon
- Strait James
- Strait Matthew
- Striganov Sergei
- Sullivan Gregory
- Sun Yujing
- Suter Louise
- Svenson Andrew
- Svoboda Robert
- Szczerbinska Barbara
- Szelc Andrzej
- Szydagis Matthew
- Söldner-Rembold Stefan
- Talaga Richard
- Tamsett Matthew
- Tariq Salman
- Tayloe Rex
- Taylor Charles
- Taylor David
- Teymourian Artin
- Themann Harry
- Thiesse Matthew
- Thomas Jenny
- Thompson Lee F.
- Thomson Mark
- Thorn Craig
- Thorpe Matt
- Tian Xinchun
- Tiedt Doug
- Toki Walter
- Tolich Nikolai
- Torti M.
- Toups Matt
- Touramanis Christos
- Tripathi Mani
- Tropin Igor
- Tsai Yun-Tse
- Tull Craig
- Tzanov Martin
- Urheim Jon
- Usman Shawn
- Vagins Mark
- Valdiviesso Gustavo
- Van Berg Rick
- Van de Water Richard
- Van Gemmeren Peter
- Varanini Filippo
- Varner Gary
- Vaziri Kamran
- Velev Gueorgui
- Ventura Sandro
- Vignoli Chiara
- Viren Brett
- Wahl Dan
- Waldron Abby
- Walter Christopher W.
- Wang Hanguo
- Wang Wei
- Warburton Karl
- Warner David
- Wasserman Ryan
- Watson Blake
- Weber Alfons
- Wei Wenzhao
- Wells Douglas
- Wetstein Matthew
- White Andy
- White Hywel
- Whitehead Lisa
- Whittington Denver
- Willhite Joshua
- Wilson Robert J.
- Winslow Lindley
- Wood Kevin
- Worcester Elizabeth
- Worcester Matthew
- Xin Tian
- Yarritu Kevin
- Ye Jingbo
- Yeh Minfang
- Yu Bo
- Yu Jae
- Yuan Tianlu
- Zani A.
- Zeller Geralyn P.
- Zhang Chao
- Zhang Chao
- Zimmerman Eric D.
- Zwaska Robert
- Publication venue
- Publication date
- 28/07/2013
- Field of study
The preponderance of matter over antimatter in the early Universe, the
dynamics of the supernova bursts that produced the heavy elements necessary for
life and whether protons eventually decay --- these mysteries at the forefront
of particle physics and astrophysics are key to understanding the early
evolution of our Universe, its current state and its eventual fate. The
Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed
plan for a world-class experiment dedicated to addressing these questions. LBNE
is conceived around three central components: (1) a new, high-intensity
neutrino source generated from a megawatt-class proton accelerator at Fermi
National Accelerator Laboratory, (2) a near neutrino detector just downstream
of the source, and (3) a massive liquid argon time-projection chamber deployed
as a far detector deep underground at the Sanford Underground Research
Facility. This facility, located at the site of the former Homestake Mine in
Lead, South Dakota, is approximately 1,300 km from the neutrino source at
Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino
charge-parity symmetry violation and mass ordering effects. This ambitious yet
cost-effective design incorporates scalability and flexibility and can
accommodate a variety of upgrades and contributions. With its exceptional
combination of experimental configuration, technical capabilities, and
potential for transformative discoveries, LBNE promises to be a vital facility
for the field of particle physics worldwide, providing physicists from around
the globe with opportunities to collaborate in a twenty to thirty year program
of exciting science. In this document we provide a comprehensive overview of
LBNE's scientific objectives, its place in the landscape of neutrino physics
worldwide, the technologies it will incorporate and the capabilities it will
possess.Comment: Major update of previous version. This is the reference document for
LBNE science program and current status. Chapters 1, 3, and 9 provide a
comprehensive overview of LBNE's scientific objectives, its place in the
landscape of neutrino physics worldwide, the technologies it will incorporate
and the capabilities it will possess. 288 pages, 116 figure
The COVID-19 pandemic: a letter to G20 leaders
- Author
- Ahearn Bertie
- Ahmed Masood
- Alphandéry Edmond
- Altwaijri HE Dr Abdulaziz Altwaijri
- Amato Giuliano
- Amersi Mohamed
- Arbour Louise
- Aria Óscar
- Aziz Shaukat
- Bajnai Gordon
- Balkenende Jan Peter
- Banda HE Joyce
- Barak Ehud
- Barletta Nicolás Ardito
- Barroso José Manuel
- Basu Kaushik
- Bazira Dr Deus
- Belka Marek
- Berggruen Nicolas
- Berglöf Erik
- Berisha Sali
- Besley Timothy
- Bildt Carl
- Birkavs Valdis
- Blair Tony
- Bolger James Brendan
- Bolton Patrick
- Bondevik Kjell Magne
- Brahimi Lakhdar
- Brown Gordon
- Brundtland Gro Harlem
- Bruton John
- Calderón Felipe
- Calderón Rafael Ángel
- Cardoso Fernando Henrique
- Chinchilla Laura
- Chissano HE Joaquim
- Clark Helen
- Constantinescu Emil
- Cousin Ertharin
- Cristiani Alfredo
- Cvetković Mirko
- Cárdenas Mauricio
- Davies Gavyn
- De Croo Herman
- de Gaulle Nathalie
- de Klerk Frederik Willem
- Derviş Kemal
- di Mauro Beatrice Weder
- Dreifuss Ruth
- Dybul Dr Mark
- Dzau Dr Victor J.
- Dzurinda Mikuláš
- Evans Gareth
- Farrar Professor Sir Jeremy
- Fischer Jan
- Fischer Joschka
- Frattini Franco
- Gaburici Chiril
- Galal Ahmed
- Gaviria César
- Gonzalez Felipe
- Graham Dr Hamish
- Grenfell Bryan
- Gurib-Fakim Ameenah
- Guriev Sergei
- Gusenbauer Alfred
- Gutiérrez Lucio
- Halonen Tarja
- Hausmann Ricardo
- Holmes Edward C.
- Holmström Bengt
- Hurtado Osvaldo
- Ibrahim Mo
- İhsanoğlu Ekmeleddin
- Ilves Toomas Hendrik
- Itzik Dalia
- Ivanić Mladen
- Ivanov Gjorge
- Jilani Hina
- Jomaa Mehdi
- Josipović Ivo
- Karlsson Mats
- Kende-Robb Caroline
- Key John
- Ki-Moon Ban
- Kikwete HE Jakaya
- Kosor Jadranka
- Kufuor HE John
- Kumaratunga Chandrika
- Köhler Horst
- Lacalle Herrera Luis Alberto
- Lagos Ricardo
- Lagumdzija Zlatko
- Lamy Pascal
- Lee Hong-Koo
- Leonard Mark
- Leterme Yves
- Letta Enrico
- Lin Professor Justin Yifu
- Livni Tzipi
- Lucinschi Petru
- Lustig Nora
- Machel Graça
- Macri Mauricio
- Mahuad Jamil
- Major Sir John
- Mara Moussa
- Margvelashvili Giorgi
- Martin Paul
- Martinelli Ricardo
- Mbeki HE Thabo
- Medgyessy Péter
- Meidani Rexhep
- Mesić Stjepan
- Mkapa HE Benjamin
- Monti Mario
- Moussa Amre
- Muscat Joseph
- Nakagawa Dawn
- Natsios Andrew
- Nishani Bujar
- Noboa Gustavo
- O'Neill Lord Jim
- Obasanjo Chief Olusegun
- Okonjo-Iweala Dr Ngozi
- Otorbayev Djoomart
- Otunbayeva Roza
- Pagrotsky Leif
- Palacio Ana
- Palmer Sir Geoffrey
- Papandreou George
- Pastrana Andrés
- Patterson P. J.
- Pissarides Christopher
- Prodi Romano
- Pronk Jan
- Quiroga Jorge
- Raad al Hussein Zeid
- Radičová Iveta
- Ramos Horta Jose
- Ribas Reig Òscar
- Robinson Mary
- Rodrik Dani
- Rodríguez Miguel Ángel
- Roman Petre
- Rudd Kevin
- Sampaio Jorge
- Sanguinetti Julio Maria
- Santos Juan Manuel
- Satyarthi Kailash
- Schüssel Wolfgang
- Serageldin Ismail
- Sexton Professor John
- Shipley Dame Jenny
- Singh Ahluwalia Montek
- Sirleaf HE Ellen Johnson
- Solana Javier
- Soros George
- Spence Michael
- Sridhar Devi
- Stern Nicholas
- Stiglitz Joseph
- Stoyanov Petar
- Straujuma Laimdota
- Sturzenegger Federico
- Suchocka Hanna
- Summers Lawrence
- Tadić Boris
- Thinley Jigme
- Thorning-Schmidt Helle
- Tkeshelashvili Eka
- Trichet Jean-Claude
- Türk Danilo
- Uteem Cassam
- Velasco Andres
- Verhofstadt Guy
- von Thadden Ernst-Ludwig
- Wantchekon Leonard
- Wei Shang-Jin
- Williams Dr Rowan
- Wolfensohn James
- Yeo George
- Yousafzai Malala
- Yushchenko Kateryna
- Yushchenko Viktor
- Zapatero José Luis Rodríguez
- Zatlers Valdis
- Zedillo Ernesto
- Zhu Min
- Çetin Hikmet
- Đelić Božidar
- Publication venue
- Publication date
- 01/01/2020
- Field of study
The Science Performance of JWST as Characterized in Commissioning
- Author
- Abell Jim
- Abney Faith
- Abul-Huda Yasin
- Acton D. Scott
- Adams Evan
- Adler David
- Aguilar Jonathan
- Ahmed Nasif
- Alarcon Rafael Ramos
- Albert Loïc
- Alberts Stacey
- Aldridge David
- Allen Marsha
- Altenburg Martin
- Alvarez Jose Lorenzo
- Andersen Greg
- Anderson Harry
- Anderson Sara
- Argyriou Ioannis
- Armstrong Amber
- Arribas Santiago
- Artigau Etienne
- Arvai Amanda
- Atkinson Charles
- Bacon Gregory
- Bair Thomas
- Banks Kimberly
- Barrientes Jaclyn
- Barringer Bruce
- Bartosik Peter
- Bast William
- Baudoz Pierre
- Beatty Thomas
- Bechtold Katie
- Beck Tracy
- Bergeron Eddie
- Bergkoetter Matthew
- Bhatawdekar Rachana
- Birkmann Stephan
- Blazek Ronald
- Blome Claire
- Boccaletti Anthony
- Boeker Torsten
- Boia John
- Bonaventura Nina
- Bond Nicholas
- Bosley Kari
- Boucarut Ray
- Bourque Matthew
- Bouwman Jeroen
- Bower Gary
- Bowers Charles
- Boyer Martha
- Bradley Larry
- Brady Greg
- Braun Hannah
- Breda David
- Bresnahan Pamela
- Bright Stacey
- Britt Christopher
- Bromenschenkel Asa
- Brooks Brian
- Brooks Keira
- Brown Bob
- Brown Matthew
- Brown Patricia
- Bunker Andy
- Burger Matthew
- Bushouse Howard
- Cale Steven
- Cameron Alex
- Cameron Peter
- Canipe Alicia
- Caplinger James
- Caputo Francis
- Cara Mihai
- Carey Larkin
- Carniani Stefano
- Carrasquilla Maria
- Carruthers Margaret
- Case Michael
- Catherine Riggs
- Chance Don
- Chapman George
- Charlot Stéphane
- Charlow Brian
- Chayer Pierre
- Chen Bin
- Cherinka Brian
- Chichester Sarah
- Chilton Zack
- Chonis Taylor
- Clampin Mark
- Clark Charles
- Clark Kerry
- Coe Dan
- Coleman Benee
- Colon Knicole
- Comber Brian
- Comeau Tom
- Connolly Dennis
- Cooper James
- Cooper Rachel
- Coppock Eric
- Correnti Matteo
- Cossou Christophe
- Coulais Alain
- Coyle Laura
- Cracraft Misty
- Curti Mirko
- Cuturic Steven
- Davis Katherine
- Davis Michael
- de Oliveira Catarina Alves
- Dean Bruce
- Del Pino Bruno Rodriguez
- DeLisa Amy
- deMeester Wim
- Dencheva Nadezhda
- Dencheva Nadia
- DePasquale Joseph
- Deschenes Jeremy
- Detre Örs Hunor
- Diaz Rosa
- Dicken Dan
- DiFelice Audrey
- Dillman Matthew
- Dixon William
- Doggett Jesse
- Donaldson Tom
- Douglas Rob
- Doyon René
- DuPrie Kimberly
- Dupuis Jean
- Durning John
- Easmin Nilufar
- Eck Weston
- Edeani Chinwe
- Egami Eiichi
- Ehrenwinkler Ralf
- Eisenhamer Jonathan
- Eisenhower Michael
- Elie Michelle
- Elliott James
- Elliott Kyle
- Ellis Tracy
- Engesser Michael
- Espinoza Nestor
- Etienne Odessa
- Etxaluze Mireya
- Falini Patrick
- Feeney Matthew
- Feinberg Lee
- Ferruit Pierre
- Ferry Malcolm
- Filippazzo Joseph
- Fincham Brian
- Fix Mees
- Flagey Nicolas
- Florian Michael
- Flynn Jim
- Fontanella Erin
- Ford Terrance
- Forshay Peter
- Fox Ori
- Franz David
- Friedman Scott
- Fu Henry
- Fullerton Alexander
- Galkin Sergey
- Galyer Anthony
- Gardner Jonathan
- Gardner Lisa
- Garland Dennis
- Garrett Bruce
- Gasman Danny
- Gaspar Andras
- Gaudreau Daniel
- Gauthier Peter
- Geers Vincent
- Geithner Paul
- Gennaro Mario
- Giardino Giovanna
- Girard Julien
- Giuliano Mark
- Glasse Alistair
- Glassmire Kirk
- Glauser Adrian
- Glazer Stuart
- Godfrey John
- Golimowski David
- Gollnitz David
- Gong Fan
- Gonzaga Shireen
- Gordon Karl
- Gordon Michael
- Goudfrooij Paul
- Greene Thomas
- Greenhouse Matthew
- Grimaldi Stefano
- Groebner Andrew
- Grundy Timothy
- Guillard Pierre
- Gutman Irvin
- Ha Kong Q.
- Haderlein Peter
- Hagedorn Andria
- Hainline Kevin
- Haley Craig
- Hami Maryam
- Hamilton Forrest
- Hammel Heidi
- Hansen Carl
- Harkins Tom
- Harr Michael
- Hart Jessica
- Hart Quyen
- Hartig George
- Hashimoto Ryan
- Haskins Sujee
- Hathaway William
- Havey Keith
- Hayden Brian
- Hecht Karen
- Heller-Boyer Chris
- Henriques Caroline
- Henry Alaina
- Hermann Karl
- Hernandez Scarlin
- Hesman Brigette
- Hicks Brian
- Hilbert Bryan
- Hines Dean
- Hoffman Melissa
- Holfeltz Sherie
- Holler Bryan J.
- Hoppa Jennifer
- Hott Kyle
- Howard Joseph
- Howard Rick
- Hunter Alexander
- Hunter David
- Hurst Brendan
- Husemann Bernd
- Hustak Leah
- Ignat Luminita Ilinca
- Illingworth Garth
- Irish Sandra
- Jackson Wallace
- Jahromi Amir
- Jakobsen Peter
- James Bryan
- James LeAndrea
- Januszewski William
- Jenkins Ann
- Jirdeh Hussein
- Johnson Phillip
- Johnson Timothy
- Jones Danny
- Jones Olivia
- Jones Ron
- Jones Vicki
- Jordan Ian
- Jordan Margaret
- Jurczyk Sarah
- Jurling Alden
- Kaleida Catherine
- Kalmanson Phillip
- Kammerer Jens
- Kang Huijo
- Kao Shaw-Hong
- Karakla Diane
- Kavanagh Patrick
- Kelly Doug
- Kendrew Sarah
- Kennedy Herbert
- Kenny Deborah
- Keski-kuha Ritva
- Keyes Charles
- Kidwell Richard
- Kimble Randy
- Kinzel Wayne
- Kirk Jeff
- Kirkpatrick Mark
- Kirshenblat Danielle
- Klaassen Pamela
- Knapp Bryan
- Knight J. Scott
- Knollenberg Perry
- Koehler Robert
- Koekemoer Anton
- Kovacs Aiden
- Kulp Trey
- Kumari Nimisha
- Kyprianou Mark
- La Massa Stephanie
- Labador Aurora
- Lagage Pierre-Olivier
- Lajoie Charles-Phillipe
- Lallo Matt
- Lallo Matthew
- Lam May
- Lamb Tracy
- Lambros Scott
- Lampenfield Richard
- Langston James
- Larson Kirsten
- Law David
- Lawrence Jon
- Lee David
- Leisenring Jarron
- Lepo Kelly
- Leveille Michael
- Levenson Nancy
- Levine Marie
- Levy Zena
- Lewis Dan
- Lewis Hannah
- Libralato Mattia
- Lightsey Paul
- Link Miranda
- Liu Lily
- Lo Amy
- Lockwood Alexandra
- Logue Ryan
- Long Chris
- Long Douglas
- Loomis Charles
- Lopez-Caniego Marcos
- Love-Pruitt Jennifer
- Lucy Adrian
- Luetzgendorf Nora
- Maghami Peiman
- Maiolino Roberto
- Major Melissa
- Malla Sunita
- Malumuth Eliot
- Manjavacas Elena
- Mannfolk Crystal
- Marin Macarena Garcia
- Marquez Javier Alvarez
- Marrione Amanda
- Marston Anthony
- Martel André
- Maschmann Marc
- Masci Gregory
- Masciarelli Michaela
- Maszkiewicz Michael
- Mather John
- McElwain Michael
- McKenzie Kenny
- McLean Brian
- McMaster Matthew
- Melbourne Katie
- Meléndez Marcio
- Menzel Michael
- Merz Kaiya
- Meyett Michele
- Meza Luis
- Milam Stefanie
- Miskey Cherie
- Misselt Karl
- Moller Christopher
- Morrison Jane
- Morse Ernie
- Moseley Harvey
- Mosier Gary
- Mountain Matt
- Mueckay Julio
- Mueller Michael
- Mullally Susan
- Murphy Jess
- Murray Claire
- Murray Katherine
- Mustelier David
- Muzerolle James
- Mycroft Matthew
- Myers Richard
- Myrick Kaila
- Nanavati Shashvat
- Nance Elizabeth
- Nayak Omnarayani
- Naylor Bret
- Neff Susan
- Neira Irma Quispe
- Nelan Edmund
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- Nikolov Nikolay
- Noriega-Crespo Alberto
- O'Shaughnessy Brian
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- Olmsted Joseph
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- Osborne Shannon
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- Pacifici Camilla
- Pagan Alyssa
- Page James
- Park Sang
- Parrish Keith
- Patapis Polychronis
- Paul Lee
- Pauly Tyler
- Pavlovsky Cheryl
- Pedder Andrew
- Peek Matthew
- Pena-Guerrero Maria
- Pennanen Konstantin
- Perez Yesenia
- Perna Michele
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- Pietraszkiewicz Martin
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- Pirzkal Norbert
- Pitman Joseph
- Piwowar Aidan
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- Player Danielle
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- Pontoppidan Klaus
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- Roth Marc
- Rothwell Braden
- Rowlands Neil
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- Royle Patricia
- Rui Chunlei
- Rumler Peter
- Runnels Joel
- Russ Melissa
- Rustamkulov Zafar
- Ryden Grant
- Ryer Holly
- Sabata Modhumita
- Sabatke Derek
- Sabbi Elena
- Samuelson Bridget
- Sapp Benjamin
- Sappington Bradley
- Sargent B.
- Sauer Arne
- Scheithauer Silvia
- Schlawin Everett
- Schlitz Joseph
- Schmitz Tyler
- Schneider Analyn
- Schreiber Jürgen
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- Shivaei Irene
- Sienkiewicz Matthew
- Sing David
- Sirianni Marco
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- Skipper Joy
- Sloan Gregory
- Slocum Christine
- Slowinski Steven
- Smith Corbett
- Smith Denise
- Smith Eric
- Smith Erin
- Snyder Gregory
- Soh Warren
- Sohn Tony
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- Spencer Richard
- Stallcup Scott
- Stansberry John
- Stark Christopher
- Starr Carl
- Starr Elysia
- Stewart Alphonso
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- Straughn Amber
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- Stys Jeff
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- Taylor Rolanda
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- Telfer Randal
- Temim Tea
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- Thomson Shaun
- Tikkanen Tuomo
- Tippet William
- Todd Connor
- Toolan Sharon
- Tran Hien
- Trejo Edwin
- Truong Justin
- Tsukamoto Chris
- Tustain Samuel
- Tyra Harrison
- Ubeda Leonardo
- Underwood Kelli
- Uzzo Michael
- Valenti Jeff
- Van Campen Julie
- Vandal Thomas
- Vandenbussche Bart
- Vila Begoña
- Volk Kevin
- Wahlgren Glenn
- Waldman Mark
- Walker Chanda
- Wander Michel
- Warfield Christine
- Warner Gerald
- Wasiak Matthew
- Watkins Mitchell
- Weaver Andrew
- Weilert Mark
- Weiser Nick
- Weiss Ben
- Weissman Sarah
- Welty Alan
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- Wheatley Elizabeth
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- Whitehouse Paul
- Whiteleather Jennifer
- Whitman William
- Williams Christina
- Willmer Christopher
- Willott Chris
- Willoughby Scott
- Wilson Andrew
- Wirth Gregory
- Wislowski Emily
- Wolf Erin
- Wolfe David
- Wolff Schuyler
- Workman Bill
- Wright Gillian
- Wright Ray
- Wu Carl
- Wu Rai
- Wymer Kristen
- Yates Kayla
- Yeager Christopher
- Yeates Jared
- Yerger Ethan
- Yoon Jinmi
- Young Alice
- Yu Susan
- Zak Dean
- Zeidler Peter
- Zhou Julia
- Zielinski Thomas
- Zincke Cristian
- Zonak Stephanie
- Publication venue
- 'IOP Publishing'
- Publication date
- 10/04/2023
- Field of study
This paper characterizes the actual science performance of the James Webb
Space Telescope (JWST), as determined from the six month commissioning period.
We summarize the performance of the spacecraft, telescope, science instruments,
and ground system, with an emphasis on differences from pre-launch
expectations. Commissioning has made clear that JWST is fully capable of
achieving the discoveries for which it was built. Moreover, almost across the
board, the science performance of JWST is better than expected; in most cases,
JWST will go deeper faster than expected. The telescope and instrument suite
have demonstrated the sensitivity, stability, image quality, and spectral range
that are necessary to transform our understanding of the cosmos through
observations spanning from near-earth asteroids to the most distant galaxies.Comment: 5th version as accepted to PASP; 31 pages, 18 figures;
https://iopscience.iop.org/article/10.1088/1538-3873/acb29
The James Webb Space Telescope Mission
- Author
- Abbott Randy
- Abell James S.
- Abernathy Mark
- Abney Faith E.
- Abraham John G.
- Abraham Roberto
- Abul-Huda Yasin M.
- Acton Scott
- Adams Cynthia K.
- Adams Evan
- Adler David S.
- Adriaensen Maarten
- Aguilar Jonathan Albert
- Ahmed Mansoor
- Ahmed Nasif S.
- Ahmed Tanjira
- Alarcon Rafael Ramos
- Albat Rüdeger
- Albert Loïc
- Alberts Stacey
- Aldridge David
- Allen Mary Marsha
- Allen Shaune S.
- Altenburg Martin
- Altunc Serhat
- Alvarez Jose Lorenzo
- Ambrose Leslie L.
- Anandakrishnan Satya M.
- Andersen Gregory C.
- Anderson Harry James
- Anderson Jay
- Anderson Kristen
- Anderson Sara M.
- Aprea Julio
- Archer Benita J.
- Arenberg Jonathan W.
- Argyriou Ioannis
- Arribas Santiago
- Artigau Étienne
- Arvai Amanda Rose
- Atcheson Paul
- Atkinson Charles B.
- Averbukh Jesse
- Aymergen Cagatay
- Bacinski John J.
- Baggett Wayne E.
- Bagnasco Giorgio
- Baker Lynn L.
- Balzano Vicki Ann
- Banks Kimberly A.
- Baran David A.
- Barker Elizabeth A.
- Barrett Larry K.
- Barringer Bruce O.
- Barto Allison
- Bast William
- Baudoz Pierre
- Baum Stefi
- Beatty Thomas G.
- Beaulieu Mathilde
- Bechtold Kathryn
- Beck Tracy
- Beddard Megan M.
- Beichman Charles
- Bellagama Larry
- Bely Pierre
- Berger Timothy W.
- Bergeron Louis E.
- Bertch Maria D.
- Beskow Charlotte
- Betz Laura E.
- Biagetti Carl P.
- Birkmann Stephan
- Bjorklund Kurt F.
- Blackwood James D.
- Blazek Ronald Paul
- Blossfeld Stephen
- Bluth Marcel
- Boccaletti Anthony
- Boegner Jr. Martin E.
- Bohlin Ralph C.
- Boia John Joseph
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- Sahu Kailash C.
- Saif Babak N.
- Salvignol Jean-Christophe
- Samara-Ratna Piyal
- Samuelson Bridget S.
- Sanders Felicia A.
- Santos Tony Dos
- Sappington Bradley
- Sargent B. A.
- Sauer Arne
- Savadkin Bruce J.
- Sawicki Marcin
- Schappell Tina M.
- Scheffer Caroline
- Scheithauer Silvia
- Scherer Ron
- Schiff Conrad
- Schlawin Everett
- Schmeitzky Olivier
- Schmitz Tyler S.
- Schmude Donald J.
- Schneider Analyn
- Schreiber Jürgen
- Schroeven-Deceuninck Hilde
- Schultz John J.
- Schwab Ryan
- Schwartz Curtis H.
- Scoccimarro Dario
- Scott John F.
- Scott Michelle B.
- Seaton Bonita L.
- Seely Bruce S.
- Seery Bernard
- Seidleck Mark
- Sembach Kenneth
- Shanahan Clare Elizabeth
- Shaughnessy Bryan
- Shaw Richard A.
- Shay Christopher Michael
- Sheehan Even
- Sheth Kartik
- Shih Hsin-Yi
- Shivaei Irene
- Siegel Noah
- Sienkiewicz Matthew G.
- Simmons Debra D.
- Simon Bernard P.
- Sirianni Marco
- Sivaramakrishnan Anand
- Slade Jeffrey E.
- Sloan G. C.
- Slocum Christine E.
- Slowinski Steven E.
- Smith Corbett T.
- Smith Eric P.
- Smith Erin C.
- Smith Koby
- Smith Robert
- Smith Stephanie J.
- Smolik John L.
- Soderblom David R.
- Sohn Sangmo Tony
- Sokol Jeff
- Sonneborn George
- Sontag Christopher D.
- Sooy Peter R.
- Soummer Remi
- Southwood Dana M.
- Spain Kay
- Sparmo Joseph
- Speer David T.
- Spencer Richard
- Sprofera Joseph D.
- Stallcup Scott S.
- Stanley Marcia K.
- Stansberry John A.
- Stark Christopher C.
- Starr Carl W.
- Stassi Diane Y.
- Steck Jane A.
- Steeley Christine D.
- Stephens Matthew A.
- Stephenson Ralph J.
- Stewart Alphonso C.
- Stiavelli Massimo
- Stockman Jr. Hervey
- Strada Paolo
- Straughn Amber N.
- Streetman Scott
- Strickland David Kendal
- Strobele Jingping F.
- Stuhlinger Martin
- Stys Jeffrey Edward
- Such Miguel
- Sukhatme Kalyani
- Sullivan Joseph F.
- Sullivan Pamela C.
- Sumner Sandra M.
- Sun Fengwu
- Sunnquist Benjamin Dale
- Swade Daryl Allen
- Swam Michael S.
- Swenton Diane F.
- Swoish Robby A.
- Tamas Laszlo
- Tao Andrew
- Taylor David K.
- Taylor Joanna M.
- Teague Kelly K.
- Telfer Randal C.
- Temim Tea
- Texter Scott C.
- Thatte Deepashri G.
- Thompson Christopher Lee
- Thompson Linda M.
- Thomson Shaun R.
- Thronson Harley
- Tierney C. M.
- Tikkanen Tuomo
- Tinnin Lee
- Tippet William Thomas
- Todd Connor William
- Tran Hien D.
- Trauger John
- Trejo Edwin Gregorio
- Truong Justin Hoang Vinh
- Tsukamoto Christine L.
- Tufail Yasir
- Tumlinson Jason
- Tustain Samuel
- Tyra Harrison
- Ubeda Leonardo
- Underwood Kelli
- Uzzo Michael A.
- Vaclavik Steven
- Valenduc Frida
- Valenti Jeff A.
- Van Campen Julie
- van de Wetering Inge
- Van Der Marel Roeland P.
- van Dishoeck Ewine F.
- van Haarlem Remy
- Van Tea Mason
- Vandenbussche Bart
- Vanterpool Dona D.
- Vernoy Michael R.
- Volk Kevin
- Voorzaat Piet
- Voyton Mark F.
- Vydra Ekaterina
- Waddy Darryl J.
- Waelkens Christoffel
- Wahlgren Glenn Michael
- Walker Jr. Frederick E.
- Wander Michel
- Warfield Christine K.
- Warner Gerald
- Wasiak Francis C.
- Wasiak Matthew F.
- Wehner James
- Weiler Kevin R.
- Weilert Mark
- Weiss Stanley B.
- Wells Martyn
- Welty Alan D.
- Wheate Lauren
- Wheeler Thomas P.
- White Christy L.
- Whitehouse Paul
- Whiteleather Jennifer Margaret
- Whitman William Russell
- Williams Christina C.
- Willmer Christopher N. A.
- Willott Chris J.
- Willoughby Scott P.
- Wilson Andrew
- Wilson Debra
- Wilson Donna V.
- Windhorst Rogier
- Wislowski Emily Christine
- Wolfe David J.
- Wolfe Michael A.
- Wolff Schuyler
- Wondel Amancio
- Woo Cindy
- Woods Robert T.
- Worden Elaine
- Workman William
- Wright Gillian S.
- Wu Carl
- Wu Chi-Rai
- Wun Dakin D.
- Wymer Kristen B.
- Yadetie Thomas
- Yan Isabelle C.
- Yang Keith C.
- Yates Kayla L.
- Yeager Christopher R.
- Yerger Ethan John
- Young Erick T.
- Young Gary
- Yu Gene
- Yu Susan
- Zak Dean S.
- Zeidler Peter
- Zepp Robert
- Zhou Julia
- Zincke Christian A.
- Zonak Stephanie
- Zondag Elisabeth
- Álvarez-Márquez Javier
- Östlin Göran
- Publication venue
- Publication date
- 10/04/2023
- Field of study
Twenty-six years ago a small committee report, building on earlier studies,
expounded a compelling and poetic vision for the future of astronomy, calling
for an infrared-optimized space telescope with an aperture of at least 4m.
With the support of their governments in the US, Europe, and Canada, 20,000
people realized that vision as the 6.5m James Webb Space Telescope. A
generation of astronomers will celebrate their accomplishments for the life of
the mission, potentially as long as 20 years, and beyond. This report and the
scientific discoveries that follow are extended thank-you notes to the 20,000
team members. The telescope is working perfectly, with much better image
quality than expected. In this and accompanying papers, we give a brief
history, describe the observatory, outline its objectives and current observing
program, and discuss the inventions and people who made it possible. We cite
detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space
Telescope Overview, 29 pages, 4 figure
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
- Author
- Abbasi Z
- Abdul-Hamid M Akhlil
- Abel Paul D
- Abrams Paul H
- Adab Fawzi A
- Adamson Andrew
- Adeyoju A
- Adolfson Jan
- Afzal Naveed
- Ahiaku Ernest K N
- Ahmed Munir
- Al Sudani Mohammed L
- Al-Samarraie Amir S M
- Al-Samerraie [Unknown]
- Al-Singary Waleed
- Al-Sudani [Unknown]
- Alcock Christopher
- Alexander Kimberly
- Ali Zulfiqar
- Almond David J
- Alonzi Roberto
- Aly Markus
- Amin Al Olama Ali
- Anderson John
- Andrews Henry
- Andrews Steven
- Anjum Iqbal
- Anson Ken
- Anyamene Nicola A
- Apakama Ike
- Aparcia F
- Archbold J A A
- Arndt Volker
- Ash D
- Ashford Richard F U
- Auvinen Anssi
- Azzabi A
- Badenoch David
- Bahl Amit
- Bailey Karen
- Bailey M J
- Ball Andrew J
- Banerjee G
- Barber Jim
- Barber N
- Baria [Unknown]
- Barnes Douglas G
- Barros-Silva Joao
- Barwell Julian
- Bashir J
- Basu Pradip
- Bates Christopher A
- Batra Jyotsna
- Bax N A
- Baxter-Smith D
- Bdesha Amar
- Beacock Christopher J M
- Beaney Ronald P
- Beard Ralph
- Beatty John D
- Beck Rupert
- Beese Gail
- Beesley Sharon
- Bell C Richard W
- Bellringer James
- Benlloch Garcia Sara
- Benson Richard
- Beresford [Unknown]
- Bevis Christopher R A
- Bhana Rajanee
- Bhanot S
- Bhatnagar A
- Bhatt R I
- Birch Brian
- Birtle Alison
- Bishop M
- Biyani C Shekhar
- Blacklock A R E
- Blades Rosemary
- Bliss Peter
- Bloomfield David J
- Boddy S
- Bollina Prasad
- Bonnington Sue
- Booth C M
- Bose Pradeep
- Bott Michael C
- Bottomley David
- Boucher Nigel R
- Bowen J
- Bower Mark
- Bowsher W G
- Boyd P J R
- Bradshaw Lynne
- Bramble F James
- Brenner Hermann
- Brewster Simon F
- Briggs Tim
- Brock Cathryn
- Brock Sue
- Bromage Stephen
- Broms Michael
- Brough Richard
- Brown Andrew A
- Brown Paul
- Brown Paul M
- Brown Richard
- Brown Stephen
- Browning Tony J
- Bryan N
- Burgess Neil A
- Burns-Cox Nicholas
- Butterbach Katja
- Butterworth Paul C
- Cahill D
- Callaghan P S
- Calleary John
- Calleja M
- Calman Frances
- Camilleri Philip
- Campbell Alister
- Cannon Andrea
- Cannon-Albright Lisa
- Carnell Dawn M
- Carr T W
- Carter Adam C
- Carter Charles J M
- Carter Simon
- Castle Bruce M
- Catto James
- Cavalli-Bjoerkman Carin
- Chadwick David
- Chahal Rohit
- Chakraborti P
- Chappell [Unknown]
- Charig C
- Chetiyawardana Anula D
- Chilton Christopher
- Chinegwundoh F I
- Chong Irene
- Choudhury Ananya
- Chow Wai-Man
- Christmas Timothy J
- Christova Svetlana
- Churn Mark J
- Cieza-Borrella Clara
- Clarke Noel W
- Clavijo-Eisele Jorge
- Clements Judith A
- Coe M
- Coetzee Gerhard A
- Cohen N P
- Coker C
- Cole David J
- Cole O
- Cole Trevor
- Collins Angus
- Collins Gerald
- Collinson Matthew
- Conn I
- Connell C
- Conti David V
- Cook Audrey
- Cook Margaret
- Cooke Peter
- Cooksey Graeme
- Coombs L
- Cooper Debbie
- Copland Robert F
- Cornaby Andrew J
- Cornford P A
- Corolis [Unknown]
- Corr John
- Costello C B
- Coull Mrs N
- Cowan Richard
- Cox Angela
- Cox Robert
- Coyle C
- Crew Jeremy
- Crisp John C
- Cross W
- Cruger Dorthe
- Crundwell Malcolm
- Cummings [Unknown]
- Cybulski Cezary
- Dadaev Tokhir
- Dahar Nazeer
- Daniel Francis N
- Darrad J
- Daruwala Pallon
- Das Gautam
- Datta Shibendra
- Davidson S
- Davies Joseph
- Davis Michael
- Davison Owen W
- Dawkins Guy
- Dawson Chris
- De Bolla Alan R
- Dearnaley David
- Desai Ken M
- Deutsch George P
- Dick John
- Dickinson Andrew J
- Dickson Jeanette
- Dikov Tihomir
- Dinneen Michael
- Dixit Sanjay
- Dobbs H Jane
- Doble A
- Doble Andrew
- Dodds David
- Doherty Alan
- Donaldson P
- Donovan Jenny L
- Dooldeniya M
- Douglas S Fiona
- Down Liz
- Drake [Unknown]
- Duchesne Gill M
- Duffy Peter
- Dunn Michael
- Dunsmuir W D
- Durkan Garrett
- Durrani Sajid K
- Easton Douglas
- Eaton Alan C
- Eccles Diane
- Eckert Allison
- Eddy B
- Eden C D
- Edwards J
- Eeles Rosalind A
- El-Modir A
- Elkabir Jeremy
- Elliott Emma
- Elliott P Tony
- Ellis B W
- Ellis R
- Elves Andrew W S
- Elwell Christine
- Emberton Mark
- Emmerson Louise
- England Roland C D
- Errington R D
- Evans D Gareth
- Falconer Alison
- Fawcett Derek
- Featherston C
- Featherstone Carolyn J
- Feggetter Jeremy
- Ferguson C
- Fermont D
- Ferro Michael
- Fisher Cyril
- Fitzgerald Liesel
- Fitzgerlad Liesel M
- Fletcher Matthew
- Folkes A
- Ford Trevor F
- Foster Paul W
- Franks Kevin N
- Freedman Mathew
- Frim Olivera
- Gale Joanna
- Gallegos Christopher
- Gelister James S
- George Anne
- Ghana [Unknown]
- Gibbs Stephanie
- Gilbert Hugh
- Giles Graham G
- Gillatt David
- Glaholm John
- Glass Jonathan M
- Glenister James
- Goode Thomas D
- Gordon E M
- Govindasami Koveela
- Gower Richard L
- Graham John
- Green Damian
- Greenland Jonathan
- Grieve Robert
- Griffiths Thomas R L
- Gronberg Henrik
- Gujral Sandy
- Gupta Nishi
- Gurun Riza Murat
- Gustafsson Sven
- Guy Michelle
- Guy Peter J
- Haiman Christopher A
- Haldar Neil
- Halder N
- Haley James
- Hamdy F C
- Hamdy Freddie
- Hamilton C
- Hammonds John
- Hampson S J
- Hanbury Damien C
- Hardman P D John
- Harland Stephen J
- Harney John M
- Harper Peter
- Harris D
- Harris Sarah
- Harrison G S M
- Harriss D R
- Harvey-Hills N
- Hawkyard Simon
- Hazel Steve
- Hazelett Dennis J
- Heath Catherine M
- Heathcote Peter
- Hehir Michael
- Hellawell Giles O
- Henderson Brian E
- Hendry David
- Henley Mike
- Henrique Rui
- Henry Ann
- Herbert Pippa
- Herkommer Kathleen
- Hetherington John
- Hickish Tamas
- Hicks James A
- Hilman Serena
- Hindley Richard
- Hindmarsh John R
- Hines John
- Hingorani M
- Ho Edwin T S
- Hodgson Shirley
- Hoffman U
- Holden David
- Holding Peter
- Hollingdale A
- Hollins Graham W
- Holmes Simon A V
- Holt Sarah
- Hopper John L
- Horan Gail
- Horwich Alan
- Hoskin Peter
- Howell Graham P
- Howson Joanne
- Hrouda D
- Huddart Robert
- Hudson Liz
- Hughes Michael
- Hughes Owen
- Hughes Rob
- Humber Caroline
- Iacovou John W
- Ibrahim A
- Inglis John A
- Irving Stuart
- Irwin C
- Iversen Peter
- Izatt Louise
- Izegbu Victor
- Jameel Basharat
- James Michael J
- James N
- James R Lester
- Javle Pradip
- Jenkins P
- Jhavar Sameer
- Johansson Jan-Erik
- Jones Chris R
- Jones David A
- Jones Gareth
- Jones Mandy
- Joseph J
- Joss Shelagh
- Jugurnauth-Little Sara
- Kachakova Darina
- Kaisary Amir
- Kaliski Alexandre L
- Kaneva Radka
- Kapur G
- Karim O
- Karlsson Ami
- Karp Stephen J
- Kedda Mary-Anne
- Keeley F X
- Kelkar Anand R
- Kelleher J P
- Kelly John
- Kenwrick Sue
- Kerr Kris
- Key Tim J
- Khan F
- Khaw Kay-Tee
- Khoo Vincent
- Kibel Adam S
- Kierzek Andrzej
- Kimber Rachel M
- Kinder R
- Kirby Roger S
- Kirk David
- Kirkbride Peter
- Kirollos Magdi M
- Klarskov Peter
- Kluzniak Wojciech
- Kockelbergh Roger
- Koenig Philip C W C
- Kooiman Gordon G
- Koreich O
- Kote-Jarai Zsofia
- Koupparis Anthony
- Kourah Mohamed
- Kraus Sigurd
- Kujala Paula
- Kujawa Magda L
- Kulkarni Ravi
- Kumar M
- Kumar Rajeev
- Kunkler Ian H
- Kynaston H
- Kynaston Howard
- Lachlan Katherine L
- Laing Robert
- Lalloo Fiona
- Lancashire M
- Lane Athene
- Langley Stephen E M
- Laniado Marc
- Larner T R
- Lau Maurice W
- Lawrence W T
- Lawson Anne
- Le Roux Pieter J
- Leader Mary
- Lee A
- Lee J O
- Lee L
- Lemburger R John
- Lennon Teresa
- Leone Priscilla
- Leongamornlert Daniel
- Lester Jason
- Leung Hing
- Lewis D Christopher
- Lewis J
- Li Qiuyan
- Lim Hui-Yi
- Lin Hui-Yi
- Liston Thomas
- Livni Naomi
- Livsey Jacqueline
- Lloyd S
- Locke Imogen
- Lodge Richard
- Logue John
- Longmuir Mark
- Lophatananon Artitaya
- Lophatonanon Artitaya
- Lubinski Jan
- Lucas Malcolm G
- Luedeke Manuel
- Luscombe C J
- Lydon Anna
- Lynch Michael
- Lynn Naing N K
- Lyons Norma
- MacDermott James P A
- Macdonagh Ruaraidh P
- Macdonald [Unknown]
- Madaan Sanjeev
- Madhava Kudingila R
- Maeaettaenen Liisa
- Maguire Joseph
- Maher E R
- Mahmood Rana
- Maia Sofia
- Maier Christiane
- Mair Graeme H M
- Malone Greg
- Malone Peter R
- Mangar Stephen A
- Mantle Mark
- Mark I
- Marsden Gemma
- Mason M D
- Mason Malcolm
- Mason Robert
- Matanhelia [Unknown]
- Matenhelia Shyam
- Matthews Philip N
- McAleese J
- McBride Donna
- Mcdonnell Shannon K
- McDonnell Shannon K
- McFarlane Jonathan
- McGrath [Unknown]
- McIlhenny Craig
- McInerney Paul
- McIntosh Gregor
- McKinna F
- McLaren Duncan
- McLarty Esther
- McMenemin Rhona
- McNeill Alan
- McNicholas T A
- Meddings Robert N
- Mee A David
- Melcher Lucinda
- Memon [Unknown]
- Menzes Pravin
- Michael Agnieszka
- Miller Marek
- Mills Robert
- Mitchell S
- Mitev Vanio
- Mithal Natasha
- Mitkova Atanaska
- Mitra Anita
- Mobb Gillian E
- Moffat Leslie E F
- Mokete [Unknown]
- Money-Kyrle Julian
- Montgomery Bruce
- Moody Hilary
- Moody Martin P
- Morgan Angela
- Morley Roland
- Morris Sean B
- Morrison Patrick
- Mort Diana
- Mostafid Amir H
- Motiwala Hanif
- Mufti Gulzar
- Muir Gordon
- Muir Kenneth
- Mumtaz Faiz
- Murphy Michael
- Murray Alexandra
- Murray Keith W
- Murrell Shirley
- Murtola Teemu
- Muthukumar D
- Naerger Harry
- Namasivayam Siva
- Nargund Vinod
- Nawrocki [Unknown]
- Neal David E
- Neilson Donald
- Nethersell A
- Newby Jacqueline C
- Newman Hugh
- Newton R
- Nielsen Sune F
- Nordestgaard Børge G
- O'Boyle P J
- O'Brien J
- O'Brien Tim S
- O'Donnell H
- O'Donoghue E
- O'Donoghue Neil
- O'Reilly P
- O'Rourke J S
- O'Sullivan Joe
- O'Sullivan Patricia
- Oakley Neil
- Ogden Chris
- Ohja Hemant
- Oliver Tim
- Omara Tracy
- Ong Eng K
- Osborn David
- Ostler Peter
- Owen J
- Palfrey Edward
- Panades Miguel
- Panakis Niki
- Pancharatnam M
- Pandha Hardev
- Pantelides Michalakis L
- Panwar U
- Parikh Omi
- Park Hyun
- Park Jong Y
- Parker Chris
- Parker Christopher H
- Parys Bohdan T
- Pascoe Sarah
- Pashayan Nora
- Patel Anup
- Paterson Joan
- Pathack S
- Pati Jhumur
- Patterson Helen
- Pattu [Unknown]
- Paul A
- Paul Alan
- Paulo Paula
- Payne Heather
- Peake David
- Pedersen John
- Pedley I
- Pengelly A
- Peracha Amjad M
- Perry Matthew
- Persad Raj
- Peters John
- Pharoah Paul
- Philp N H
- Philp T
- Pickering Lisa M
- Pigott Katharine
- Pinto Pedro
- Plail R
- Plowman P Nicholas
- Pocock Richard D
- Pope A J
- Popert Rick
- Popov Elenko
- Porter Tim
- Potter John M
- Pow-Sang Julio
- Powell Christopher
- Powell Philip
- Powles Thomas B
- Prasad Krishna
- Prasad Seshadri Sri
- Prejbisz J W
- Prescott Stephen
- Protheroe Andrew
- Qureshi Khaver N
- Raby Nigel
- Radlein Selina
- Ragavan Narasimhan
- Raju Palaniappa G S
- Ramachandra Prakash B
- Raman R
- Rane Abhay
- Rankin Julia
- Rao Y
- Ratan Hari L
- Ravi Ramachandran
- Ravishankar K
- Read [Unknown]
- Reddy Paul J
- Rimington Peter R
- Rinckleb Antje
- Rincon Maria
- Riska Shaun
- Ritchie Peter A
- Roberts J Trevor
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- Robinson Angus
- Robinson Anne C
- Robinson Lee Q
- Rochester Mark A
- Roder Andreas
- Rogers P B
- Rosario Derek
- Rosenbaum Tomas P
- Rothwell Neil
- Rowbotham Carl
- Rowe [Unknown]
- Rowley Kathryn
- Ruddy Deborah
- Rundle John
- Russell John M
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- Sabharwal A
- Saggar Anand K
- Samanci Ali
- Sangar Vijay K
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- Saunders Edward J
- Saunders Pamela
- Sawyer Emma J
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- Schleutker Johanna
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- Scoble John E
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- Sellers Thomas
- Sells Henry
- Sethia Krishna K
- Severi Gianluca
- Shackley David C
- Shaffer [Unknown]
- Shah Nihil
- Shakespeare D
- Shanley Sue
- Sharma Neerah K
- Sheehan Denise J
- Sherwin Elizabeth
- Shum Poh Lin
- Side Lucy
- Sidek Norma
- Signorello Lisa B
- Sikora Karol
- Simcock R
- Sinclair Andrew M
- Singh Pravin
- Siva M
- Slavov Chavdar
- Smith James
- Smith Michael F
- Sokal Michael
- Sole Graham M
- Southey Melissa C
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- Spurdle Amanda
- Sreenivasan Thiagarajan
- Srihari Narayanan N
- Srinivasan [Unknown]
- Sriram Rajagopalan
- Staffurth John N
- Stanford Janet L
- Stattin Paer
- Stegmaier Christa
- Stephens Sarah
- Stewart D
- Stockdale Andrew
- Stott Mark A
- Stower M J
- Strachan John R
- Stuart Nicholas S A
- Sugden Elaine
- Summerton Duncan
- Sundar Santhanam
- Sundaram S K
- Suresh Gokarakonda
- Susnerwala Shabbir
- Swami Kuchibhotla S
- Symons Stephanie J
- Syndikus Isabel
- Taari Kimmo
- Tahir Saad
- Tammela Teuvo L
- Tammela Teuvo L J
- Tanquay J
- Taylor J W
- Taylor John W
- Teixeira Manuel R
- Terry T
- Thibodeau Stephen N
- Thomas Robert J
- Thomas Stephen A
- Thompson Alan
- Thompson Pauline
- Thomson Alastair H
- Thurston A
- Tidball Sarah
- Tillmans Lori
- Tilsley Owen
- Tindall Stuart F
- Tipples K
- Tong [Unknown]
- Toussi Hamid
- Toy Elizabeth W
- Travis Ruth C
- Trembath Richard C
- Tulloch David N
- Turner Kevin J
- Turner Megan
- Tweedle James
- Tymrakiewicz Malgorzata
- Tyrell C J
- Umez-Eronini N
- Urwin Graeme H
- Vale Justin A
- Van As [Unknown]
- Van As Nicholas
- Vasanthan Subramaniam
- Vesey Sean
- Vilarino-Varela Maria
- Violet John
- Virdi Jaspal
- Viñuela Ana
- Vlahova Aleksandrina
- Vogel Walther
- Wade Robert
- Wahlfors Tiina
- Waite Katherine
- Walker E M
- Walker Roger
- Wallace David M A
- Wallinder Hans
- Wang Liang
- Watkin Nicholas A
- Watson M E
- Waxman J H
- Waymont Brian
- Weaver Andrew
- Webb Ralph J
- Wedderburn Andrew
- Weischer Maren
- Wells Paula
- Wemyss-Holden G D
- Weston P M T
- Wheatley Duncan
- Whelan P
- Whillis D
- Whitmore Ian
- Wiklund Fredrik
- Wilde Adam D
- Wiles Vicki
- Wilkins Marie
- Wilkinson Rosemary
- Williams John H
- Williams Simon
- Willis Michael
- Wills Michael I
- Wilson J R
- Wilson Richard
- Winkler Mathias H
- Wise Marcus
- Wokozorczyk Dominika
- Wokołorczyk Dominika
- Wood Glenn
- Woodhams Simon
- Woodhouse C
- Woodward Cathryn
- Woolf [Unknown]
- Woolfenden K A
- Worlding Jane
- Wright Mark
- Wu Huihai
- WYLIE [Unknown]
- Wylie James P
- Wynne Chris
- Yeadon Trina
- Zachariah Babu
- Zang Angelika
- Zarkar A
- Zheng Wei
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2015
- Field of study
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector
- Author
- Aaboud Morad
- Aad Georges
- Abbott Brad
- Abdinov Ovsat
- Abeloos Baptiste
- Abidi Syed
- AbouZeid Ossama
- Abraham Nicola
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby
- Adachi Shunsuke
- Adamczyk Leszek
- Adelman Jahred
- Adersberger Michael
- Adye Tim
- Affolder Tony
- Afik Yoav
- Agatonovic-Jovin Tatjana
- Agheorghiesei Catalin
- Aguilar-Saavedra Juan
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
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- Akerstedt Henrik
- Akilli Ece
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- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
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- Ali Babar
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- Alvarez Gonzalez Barbara
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- Amelung Christoph
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- Ancu Lucian
- Andari Nansi
- Andeen Timothy
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- Andrei George
- Angelidakis Stylianos
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- Anisenkov Alexey
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- Caminal Armadans Roger
- Camincher Clement
- Campana Simone
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- Campoverde Angel
- Canale Vincenzo
- Cano Bret Marc
- Cantero Josu
- Cao Tingting
- Capeans Garrido Maria
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- Capua Marcella
- Carbone Ryne
- Cardarelli Roberto
- Cardillo Fabio
- Carli Ina
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- Carlino Gianpaolo
- Carlson Benjamin
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- Carney Rebecca
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German
- Carrá Sonia
- Casadei Diego
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- Casper David
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- Cheremushkina Evgeniya
- Cherkaoui El Moursli Rajaa
- Cheu Elliott
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- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Chiodini Gabriele
- Chisholm Andrew
- Chitan Adrian
- Chiu Yu
- Chizhov Mihail
- Choi Kyungeon
- Chomont Arthur
- Chouridou Sofia
- Chow Yun
- Christodoulou Valentinos
- Chu Ming
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- Chytka Ladislav
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- Cochran James
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- Cole Brian
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- Collot Johann
- Colombo Tommaso
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon
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- Conti Geraldine
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- Cooke Mark
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- Cortes-Gonzalez Arely
- Costa Giuseppe
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- Costanzo Davide
- Cottin Giovanna
- Cowan Glen
- Cox Brian
- Cranmer Kyle
- Crawley Samuel
- Creager Rachael
- Cree Graham
- Crescioli Francesco
- Cribbs Wayne
- Cristinziani Markus
- Croft Vince
- Crosetti Giovanni
- Crépé-Renaudin Sabine
- Cueto Ana
- Cuhadar Donszelmann Tulay
- Cukierman Aviv
- Cummings Jane
- Curatolo Maria
- Czekierda Sabina
- Czodrowski Patrick
- Cúth Jakub
- D'amen Gabriele
- D'Auria Saverio
- D'Eramo Louis
- D'Onofrio Monica
- Da Cunha Sargedas De Sousa Mario
- Da Via Cinzia
- Dabrowski Wladyslaw
- Dado Tomas
- Dai Tiesheng
- Dale Orjan
- Dallaire Frederick
- Dallapiccola Carlo
- Dam Mogens
- Dandoy Jeffrey
- Daneri Maria
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- Daniells Andrew
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- de Asmundis Riccardo
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- Yamane Fumiya
- Yamatani Masahiro
- Yamazaki Tomohiro
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
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- Yang Yi
- Yang Zongchang
- Yao Weiming
- Yap Yee
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yigitbasi Efe
- Yildirim Eda
- Yorita Kohei
- Yoshihara Keisuke
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- Young Christopher
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- Yuen Stephanie
- Yusuff Imran
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- Zaidan Remi
- Zaitsev Alexander
- Zakharchuk Nataliia
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanzi Daniele
- Zeitnitz Christian
- Zemaityte Gabija
- Zemla Andrzej
- Zeng Jian
- Zeng Qi
- Zenin Oleg
- Zerwas Dirk
- Zhang Dengfeng
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Liqing
- Zhang Matt
- Zhang Peng
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Yu
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhou Bing
- Zhou Chen
- Zhou Li
- Zhou Maosen
- Zhou Mingliang
- Zhou Ning
- Zhou You
- Zhu Cheng
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- Zou Rui
- zur Nedden Martin
- Zwalinski Lukasz
- Åkesson Torsten
- Šfiligoj Tina
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
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- Bentley Andrew
- Bentley Dan
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- Bercovitz John
- Berghoff Amy
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- Beugelsdijk Tony J.
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- Brady Nicola
- Brandriff Brigitte F.
- Brannon Wade
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- Bridgers Michael
- Brimhall Angela K.
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- Brook Jonathan
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- Brottier Philippe
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- Brown Jacqui
- Brown Margaret
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- Brown Michael
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- Bryant Jackie
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- Buckingham Judith M.
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- Buczek Donald
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- Burgin Matt
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- Burrell Kevin L.
- Burrill Wayne
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- Burton John
- Butcher Phil
- Butler Adam
- Butler Jon
- Butler Paul
- Caenepeel Sean
- Cahill Patrick
- Cai Tianjing
- Cai Zhen
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- Callen David F.
- Camarata Jody
- Camire David
- Camm Nick
- Campbell Christopher
- Campbell Connie S.
- Campbell Evelyn W.
- Campbell Mary I.
- Campbell Mary L.
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- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M.
- Abd-Allah Foad
- Abdulkader Rizwan Suliankatchi
- Abdulle Abdishakur M.
- Abebo Teshome Abuka
- Abera Semaw Ferede
- Aboyans Victor
- Abu-Raddad Laith J.
- Ackerman Ilana N.
- Adedeji Isaac A.
- Adedji
- Adetokunboh Olatunji
- Afshin Ashkan
- Aggarwal Rakesh
- Agrawal Anurag
- Agrawal Sutapa
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Aiyar Sneha
- Akinyemiju Tomi F.
- Akseer Nadia
- Al Lami Faris Hasan
- Al-Aly Ziyad
- Al-Maskari Fatma
- Al-Raddadi Rajaa
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Tahiya
- Alasfoor Deena
- Alene Kefyalew Addis
- Ali Raghib
- Alizadeh-Navaei Reza
- Alkaabi Juma M.
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine
- Almazroa Mohammad Abdulaziz
- Alsharif Ubai
- Alsowaidi Shirina
- Althouse Benjamin M.
- Altirkawi Khalid A.
- Alvis-Guzman Nelson
- Amare Azmeraw T.
- Amini Erfan
- Ammar Walid
- Amoako Yaw Ampem
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Arora Megha
- Artaman Al
- Arthur Avokpaho Euripide Frinel G.
- Aryal Krishna Kumar
- Asgedom Solomon W.
- Atey Tesfay Mehari
- Atnafu Niguse Tadele
- Avila-Burgos Leticia
- Awasthi Ashish
- Awasthi Shally
- Azarpazhooh Mahmoud Reza
- Azzopardi Peter
- Babalola Tesleem Kayode
- Bacha Umar
- Badawi Alaa
- Balakrishnan Kalpana
- Bannick Marlena S.
- Barac Aleksandra
- Barker-Collo Suzanne L.
- Barquera Simon
- Barrero Lope H.
- Basu Sanjay
- Battista Robert
- Battle Katherine E.
- Baune Bernhard T.
- Bazargan-Hejazi Shahrzad
- Beardsley Justin
- Bedi Neeraj
- Bekele Bayu Begashaw
- Bell Michelle L.
- Bennett Derrick A.
- Bennett James R.
- Bensenor Isabela M.
- Benson Jennifer
- Berhane Adugnaw
- Berhe Derbew Fikadu
- Bernabé Eduardo
- Betsu Balem Demtsu
- Beuran Mircea
- Beyene Addisu Shunu
- Bhansali Anil
- Bhatt Samir
- Bhutta Zulfqar A.
- Biadgilign Sibhatu
- Bicer Burcu Kucuk
- Bienhof Kelly
- Bikbov Boris
- Birungi Charles
- Biryukov Stan
- Bisanzio Donal
- Bizuayehu Habtamu Mellie
- Blyth Fiona M.
- Boneya Dube Jara
- Bose Dipan
- Bou-Orm Ibrahim R.
- Bourne Rupert R. A.
- Brainin Michael
- Brayne Carol E. G.
- Brazinova Alexandra
- Breitborde Nicholas J. K.
- Briant Paul S.
- Britton Gabrielle
- Brugha Traolach S.
- Bryane
- Buchbinder Rachelle
- Bulto Lemma Negesa Bulto
- Bumgarner Blair
- Butt Zahid A.
- Bärnighausen Till
- Béjot Yannick
- Cahuana-Hurtado Lucero
- Cameron Ewan
- Campos-Nonato Ismael Ricardo
- Carabin Hélène
- Carpenter David O.
- Carrero Juan Jesus
- Carter Austin
- Carvalho Felix
- Casey Daniel
- Castañeda-Orjuela Carlos A.
- Castle Chris D.
- Catalá-López Ferrán
- Chang Jung-Chen
- Charlson Fiona J.
- Chaturvedi Pankaj
- Chen Honglei
- Chibalabala Mirriam
- Chibueze Chioma Ezinne
- Chisumpa Vesper Hichilombwe
- Chitheer Abdulaal A.
- Chowdhury Rajiv
- Christopher Devasahayam Jesudas
- Ciobanu Liliana G.
- Cirillo Massimo
- Colombara Danny
- Cooper Cyrus
- Cooper Leslie Trumbull
- Cortesi Paolo Angelo
- Cortinovis Monica
- Criqui Michael H.
- Cromwell Elizabeth A.
- Cross Marita
- Crump John A.
- Cárdenas Rosario
- Dadi Abel Fekadu
- Dalal Koustuv
- Damasceno Albertino
- Dandona Lalit
- Dandona Rakhi
- Das Jarlais Don C.
- Das Neves José
- Davitoiu Dragos V.
- Davletov Kairat
- De Courten Barbora
- De Leo Diego
- De Steur Hans
- Defo Barthelemy Kuate
- Degenhardt Louisa
- Deiparine Selina
- Dellavalle Robert P.
- Deribe Kebede
- Deribew Amare
- Dey Subhojit
- Dharmaratne Samath D.
- Dhillon Preet K.
- Dicker Daniel
- Djalalinia Shirin
- Do Huyen Phuc
- Dokova Klara
- Doku David Teye
- Dorsey E. Ray
- Dos Santos Kadine Priscila Bender
- Driscoll Tim R.
- Dubey Manisha
- Duncan Bruce Bartholow
- Ebel Beth E.
- Echko Michelle
- El-Khatib Ziad Ziad
- Enayati Ahmadali
- Endries Aman Yesuf
- Ermakov Sergey Petrovich
- Erskine Holly E.
- Eshetie Setegn
- Eshrati Babak
- Esteghamati Alireza
- Estep Kara
- Fanuel Fanuel Belayneh Bekele
- Farag Tamer
- Farinha Carla Sofa E Sa
- Faro André
- Farzadfar Farshad
- Fazeli Mir Sohail
- Feigin Valery L.
- Feigl Andrea B.
- Fereshtehnejad Seyed-Mohammad
- Fernandes João C.
- Ferrari Alize J.
- Feyissa Tesfaye Regassa
- Filip Irina
- Fischer Florian
- Fitzmaurice Christina
- Flaxman Abraham D.
- Foigt Nataliya
- Foreman Kyle J.
- Franklin Richard C.
- Frostad Joseph J.
- Fullman Nancy
- Furtado Joao M.
- Futran Neal D.
- Fürst Thomas
- Gakidou Emmanuela
- Garcia-Basteiro Alberto L.
- Gebre Teshome
- Gebregergs Gebremedhin Berhe
- Gebrehiwot Tsegaye Tewelde
- Geleijnse Johanna M.
- Geleto Ayele
- Gemechu Bikila Lencha
- Gesesew Hailay Abrha
- Gething Peter W.
- Ghajar Alireza
- Gibney Katherine B.
- Gillum Richard F.
- Ginawi Ibrahim Abdelmageem Mohamed
- Gishu Melkamu Dedefo
- Giussani Giorgia
- Godwin William W.
- Goel Kashish
- Goenka Shifalika
- Goldberg Ellen M.
- Gona Philimon N.
- Goodridge Amador
- Gopalani Sameer Vali
- Gosselin Richard A.
- Gotay Carolyn C.
- Goto Atsushi
- Goulart Alessandra Carvalho
- Graetz Nicholas
- Gugnani Harish Chander
- Gupta Prakash C.
- Gupta Rahul
- Gupta Rajeev
- Gupta Tanush
- Gupta Vipin
- Gutiérrez Reyna A.
- Hachinski Vladimir
- Hafezi-Nejad Nima
- Hailu Alemayehu Desalegne
- Hailu Gessessew Bugssa
- Hamadeh Randah Ribhi
- Hamidi Samer
- Hammami Mouhanad
- Handal Alexis J.
- Hankey Graeme J.
- Hao Yuantao
- Harb Hilda L.
- Hareri Habtamu Abera
- Haro Josep Maria
- Harun Kimani M.
- Harvey James
- Hassanvand Mohammad Sadegh
- Havmoeller Rasmus
- Hay Roderick J.
- Hay Simon I.
- Hedayati Mohammad T.
- Hendrie Delia
- Henry Nathaniel J.
- Heredia-Pi Ileana Beatriz
- Heydarpour Pouria
- Hoek Hans W.
- Hofman Howard J.
- Horino Masako
- Horita Nobuyuki
- Hosgood H. Dean
- Hostiuc Sorin
- Hotez Peter J.
- Hoy Damian G.
- Htet Aung Soe
- Hu Guoqing
- Huang John J.
- Huynh Chantal
- Iburg Kim Moesgaard
- Igumbor Ehimario Uche
- Ikeda Chad
- Irvine Caleb Mackay Salpeter
- Jacobsen Kathryn H.
- Jahanmehr Nader
- Jakovljevic Mihajlo B.
- James Peter
- Jassal Simerjot K.
- Javanbakht Mehdi
- Jayaraman Sudha P.
- Jeemon Panniyammakal
- Jensen Paul N.
- Jha Vivekanand
- Jiang Guohong
- John Denny
- Johnson Catherine O.
- Johnson Sarah Charlotte
- Jonas Jost B.
- Jürisson Mikk
- Kabir Zubair
- Kadel Rajendra
- Kahsay Amaha
- Kamal Ritul
- Kar Chittaranjan
- Karam Nadim E.
- Karch André
- Karema Corine Kakizi
- Karimi Seyed M.
- Karimkhani Chante
- Kasaeian Amir
- Kassa Getachew Mullu
- Kassaw Nigussie Assefa
- Kassebaum Nicholas J.
- Kastor Anshul
- Katikireddi Srinivasa Vittal
- Kaul Anil
- Kawakami Norito
- Keiyoro Peter Njenga
- Kemmer Laura
- Kengne Andre Pascal
- Keren Andre
- Kesavachandran Chandrasekharan Nair
- Khader Yousef Saleh
- Khalil Ibrahim A.
- Khan Ejaz Ahmad
- Khang Young-Ho
- Khoja Abdullah T.
- Khosravi Ardeshir
- Khubchandani Jagdish
- Kiadaliri Aliasghar Ahmad
- Kieling Christian
- Kim Daniel
- Kim Yun Jin
- Kimokoti Ruth W.
- Kinfu Yohannes
- Kisa Adnan
- Kissimova-Skarbek Katarzyna A.
- Kissoon Niranjan
- Kivimaki Mika
- Knudsen Ann Kristin
- Kokubo Yoshihiro
- Kolte Dhaval
- Kopec Jacek A.
- Kosen Soewarta
- Kotsakis Georgios A.
- Koul Parvaiz A.
- Koyanagi Ai
- Kravchenko Michael
- Krohn Kristopher J.
- Kumar G. Anil
- Kumar Pushpendra
- Kyu Hmwe H.
- Lager Anton Carl Jonas
- Lal Dharmesh Kumar
- Lalloo Ratilal
- Lallukka Tea
- Lambert Nkurunziza
- Lan Qing
- Lansingh Van C.
- Larsson Anders
- Leasher Janet L.
- Lee Paul H.
- Leigh James
- Leshargie Cheru Tesema
- Leung Janni
- Leung Ricky
- Levi Miriam
- Li Yichong
- Li Yongmei
- Liang Xiaofeng
- Liben Misgan Legesse
- Lim Stephen S.
- Linn Shai
- Liu Angela
- Liu Patrick Y.
- Liu Shiwei
- Liu Yang
- Lodha Rakesh
- Logroscino Giancarlo
- Looker Katharine J.
- Lopez Alan D.
- Lorkowski Stefan
- Lotufo Paulo A.
- Lozano Rafael
- Lucas Timothy C. D.
- Lunevicius Raimundas
- Lyons Ronan A.
- Macarayan Erlyn Rachelle King
- Maddison Emilie R.
- Magdy Abd El Razek Hassan
- Magdy Abd El Razek Mohammed
- Magis-Rodriguez Carlos
- Mahdavi Mahdi
- Majdan Marek
- Majdzadeh Reza
- Majeed Azeem
- Malekzadeh Reza
- Malhotra Rajesh
- Malta Deborah Carvalho
- Mamun Abdullah A.
- Manguerra Helena
- Manhertz Treh
- Mantovani Lorenzo G.
- Mapoma Chabila C.
- March Lyn M.
- Marczak Laurie B.
- Martinez-Raga Jose
- Martins Paulo Henrique Viegas
- Martins-Melo Francisco Rogerlândio
- Martopullo Ira
- Mathur Manu Raj
- Mazidi Mohsen
- McAlinden Colm
- McGaughey Madeline
- McGrath John J.
- McKee Martin
- Mehata Suresh
- Meier Toni
- Meles Kidanu Gebremariam
- Memiah Peter
- Memish Ziad A.
- Mendoza Walter
- Mengesha Melkamu Merid
- Mengistie Mubarek Abera
- Mengistu Desalegn Tadese
- Mensah George A.
- Meretoja Atte
- Meretoja Tuomo J.
- Mezgebe Haftay Berhane
- Micha Renata
- Millear Anoushka
- Miller Ted R.
- Minnig Shawn
- Mirarefn Mojde
- Mirrakhimov Erkin M.
- Misganaw Awoke
- Mishra Shiva Raj
- Mitchell Philip B.
- Mohammad Karzan Abdulmuhsin
- Mohammadi Alireza
- Mohammed Kedir Endris
- Mohammed Muktar Sano Kedir
- Mohammed Shafu
- Mohan Murali B. V.
- Mokdad Ali H.
- Mollenkopf Sarah K.
- Monasta Lorenzo
- Montañez Hernandez Julio Cesar
- Montico Marcella
- Moradi-Lakeh Maziar
- Moraga Paula
- Morawska Lidia
- Mori Rintaro
- Morrison Shane D.
- Moses Mark
- Mountjoy-Venning Clif
- Mruts Kalayu Birhane
- Mudoch Michele E.
- Mueller Ulrich O.
- Muller Kate
- Murdoch
- Murray Christopher J. L.
- Murthy Gudlavalleti Venkata Satyanarayana
- Murthy Srinivas
- Musa Kamarul Imran
- März Winfried
- Nachega Jean B.
- Nagel Gabriele
- Naghavi Mohsen
- Naheed Aliya
- Naidoo Kovin S.
- Nangia Vinay
- Nasher Jamal T.
- Natarajan Gopalakrishnan
- Negasa Dumessa Edessa
- Negoi Ionut
- Negoi Ruxandra Irina
- Newton Charles R.
- Ngunjiri Josephine Wanjiku
- Nguyen Cuong Tat
- Nguyen Grant
- Nguyen Minh
- Nguyen Quyen Le
- Nguyen Trang Huyen
- Nichols Emma
- Ningrum Dina Nur Anggraini
- Nong Vuong Minh
- Norheim Ole F.
- Norrving Bo
- Noubiap Jean Jacques N.
- Nyandwi Alypio
- O'Donnell Martin J.
- Obermeyer Carla Makhlouf
- Ogbo Felix Akpojene
- Oh In-Hwan
- Okoro Anselm
- Oladimeji Olanrewaju
- Olagunju Andrew Toyin
- Olagunju Tinuke Oluwasefunmi
- Olsen Helen E.
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Ong Kanyin
- Opio John Nelson
- Oren Eyal
- Ortiz Alberto
- Osborne Richard H.
- Osgood-Zimmerman Aaron
- Osman Majdi
- Ota Erika
- Owolabi Mayowa O.
- Pa Mahesh
- Pacella Rosana E.
- Panda Basant Kumar
- Pandian Jeyaraj D.
- Papachristou Christina
- Park Eun-Kee
- Parry Charles D.
- Parsaeian Mahboubeh
- Patil Snehal T.
- Patten Scott B.
- Patton George C.
- Paudel Deepak
- Paulson Katherine
- Pearce Neil
- Pereira David M.
- Perez Krystle Marie
- Perico Norberto
- Pesudovs Konrad
- Peterson Carrie Beth
- Petri William Arthur
- Petzold Max
- Phillips Michael Robert
- Phipps Geofrey
- Pigott David M.
- Pillay Julian David
- Pinho Christine
- Piradov Michael A.
- Plass Dietrich
- Pletcher Martin A.
- Popova Svetlana
- Poulton Richie G.
- Pourmalek Farshad
- Prabhakaran Dorairaj
- Prasad Narayan
- Purcell Carrie
- Purwar Manorama
- Qorbani Mostafa
- Quintanilla Beatriz Paulina Ayala
- Rabiee Rynaz H. S.
- Radfar Amir
- Rafay Anwar
- Rahimi Kazem
- Rahimi-Movaghar Afarin
- Rahimi-Movaghar Vafa
- Rahman Mahfuzar
- Rahman Mohammad Hifz Ur
- Rahman Muhammad Aziz
- Rai Rajesh Kumar
- Rajsic Sasa
- Ram Usha
- Ranabhat Chhabi Lal
- Rangaswamy Thara
- Rankin Zane
- Rao Paturi Vishnupriya
- Rao Puja C.
- Rawaf Salman
- Ray Sarah E.
- Reiner Robert C.
- Reinig Nikolas
- Reitsma Marissa
- Remuzzi Giuseppe
- Renzaho Andre M. N.
- Resnikof Serge
- Rezaei Satar
- Ribeiro Antonio L.
- Rivas Jacqueline Castillo
- Roba Hirbo Shore
- Robinson Stephen R.
- Rojas-Rueda David
- Rokni Mohammad Bagher
- Ronfani Luca
- Roshandel Gholamreza
- Roth Gregory A.
- Rothenbacher Dietrich
- Roy Ambuj
- Rubagotti Enrico
- Ruhago George Mugambage
- Saadat Soheil
- Safdarian Mahdi
- Safri Saeid
- Sagar Rajesh
- Sahathevan Ramesh
- Sahraian Mohammad Ali
- Salama Joseph
- Saleh Muhammad Muhammad
- Salomon Joshua A.
- Salvi Sundeep Santosh
- Samy Abdallah M.
- Sanabria Juan Ramon
- Sanchez-Niño Maria Dolores
- Santomauro Damian
- Santos Itamar S.
- Santos João Vasco
- Santric Milicevic Milena M.
- Sartorius Benn
- Satpathy Maheswar
- Sawhney Monika
- Saxena Sonia
- Schelonka Kathryn
- Schmidt Maria Inês
- Schneider Ione J. C.
- Schutte Aletta E.
- Schwebel David C.
- Schwendicke Falk
- Schöttker Ben
- Seedat Soraya
- Sepanlou Sadaf G.
- Servan-Mori Edson E.
- Shaheen Amira
- Shaikh Masood Ali
- Shamsipour Mansour
- Shariful Islam Sheikh Mohammed
- Sharma Jayendra
- Sharma Rajesh
- She Jun
- Shi Peilin
- Shibuya Kenji
- Shields Chloe
- Shiferaw Mekonnen Sisay
- Shigematsu Mika
- Shiri Rahman
- Shirkoohi Reza
- Shirude Shreya
- Shishani Kawkab
- Shoman Haitham
- Siabani Soraya
- Sibai Abla Mehio
- Sigfusdottir Inga Dora
- Silberberg Donald H.
- Silva Diego Augusto Santos
- Silva João Pedro
- Silveira Dayane Gabriele Alves
- Singh Jasvinder A.
- Singh Narinder Pal
- Singh Om Prakash
- Singh Virendra
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Skirbekk Vegard
- Slepak Erica Leigh
- Smith David L.
- Smith Mari
- Sobaih Badr H. A.
- Sobngwi Eugene
- Soljak Michael
- Sorensen Reed J. D.
- Sousa Tatiane Cristina Moraes
- Sposato Luciano A.
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Stanaway Jefrey D.
- Stathopoulou Vasiliki
- Steel Nicholas
- Stein Dan J.
- Steiner Caitlyn
- Steinke Sabine
- Stokes Mark Andrew
- Stovner Lars Jacob
- Strub Bryan
- Subart Michelle
- Sufyan Muawiyyah Babale
- Sunguya Bruno F.
- Sur Patrick J.
- Swaminathan Soumya
- Sykes Bryan L.
- Sylte Dillon
- Szoeke Cassandra E. I.
- Tabarés-Seisdedos Rafael
- Tadakamadla Santosh Kumar
- Tafere Getachew Redae
- Takala Jukka S.
- Tandon Nikhil
- Tanne David
- Tarekegn Yihunie L.
- Tavakkoli Mohammad
- Taveira Nuno
- Taylor Hugh R.
- Tegegne Teketo Kassaw
- Tehrani-Banihashemi Arash
- Tekelab Tesfalidet
- Temam Shifa Girma
- Terkawi Abdullah Sulieman
- Tesfaye Dawit Jember
- Tesssema Belay
- Thakur
- Thamsuwan Ornwipa
- Theadom Alice M.
- Theis Andrew M.
- Thomas Katie E.
- Thomas Nihal
- Thompson Robert
- Thrift Amanda G.
- Tobe-Gai Ruoyan
- Tobollik Myriam
- Tonelli Marcello
- Topor-Madry Roman
- Tortajada Miguel
- Touvier Mathilde
- Traebert Jeferson
- Tran Bach Xuan
- Troeger Christopher
- Truelsen Thomas
- Tsoi Derrick
- Tuzcu Emin Murat
- Tymeson Hayley
- Tyrovolas Stefanos
- Ukwaja Kingsley Nnanna
- Undurraga Eduardo A.
- Uneke Chigozie Jesse
- Updike Rachel
- Uthman Olalekan A.
- Uzochukwu Benjamin S. Chudi
- Van Boven Job F. M.
- Varughese Santosh
- Vasankari Tommi
- Veerman Lennert J.
- Venkatesh
- Venketasubramanian Narayanaswamy
- Vidavalur Ramesh
- Vijayakumar Lakshmi
- Violante Francesco S.
- Vishnu Abhishek
- Vladimirov Sergey K.
- Vlassov Vasiliy Victorovich
- Vollset Stein Emil
- Vos Theo
- Wadilo Fiseha
- Wakayo Tolassa
- Wallin Mitchell T.
- Wang Yuan-Pang
- Weichenthal Scott
- Weiderpass Elisabete
- Weintraub Robert G.
- Weiss Daniel J.
- Werdecker Andrea
- Westerman Ronny
- Whiteford Harvey A.
- Wijeratne Tissa
- Williams Hywel C.
- Wiysonge Charles Shey
- Woldeyes Belete Getahun
- Wolfe Charles D. A.
- Woodbrook Rachel
- Woolf Anthony D.
- Workicho Abdulhalik
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yaghoubi Mohsen
- Yakob Bereket
- Yan Lijing L.
- Yano Yuichiro
- Ye Pengpeng
- Yihdego Mahari Gidey
- Yimam Hassen Hamid
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Yu Chuanhua
- Zaidi Zoubida
- Zaki Maysaa El Sayed
- Zegeye Elias Asfaw
- Zenebe Zerihun Menlkalew
- Zhang Xueying
- Zheng Yingfeng
- Zhou Maigeng
- Zipkin Ben
- Zodpey Sanjay
- Zoeckler Leo
- Zuhlke Liesl Joanna
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2017
- Field of study
BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI).
METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate.
FINDINGS: The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9-78·6) for females and 72·0 years (68·8-75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0-49·5]) and for males was in Lesotho (41·5 years [39·0-44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97-6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74-6·27) for males and 6·49 years (6·08-6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61-1·93) for males and 1·96 years (1·69-2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (-2·3% [-5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16·1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally.
INTERPRETATION: At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support.
FUNDING: Bill & Melinda Gates Foundation
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants
- Author
- Abbas Dehghan
- Abdonas Tamosiunas
- Abdullatif S Husseini
- Abhijit Sen
- Abla M Sibai
- Adela Chirita-Emandi
- Adolfo Rubinstein
- Afshin Ostovar
- Ahmad Ali Noorbala
- Ahmad Ali Zainuddin
- Ahmad Faudzi Yusoff
- Aicha Soumare
- Aida Pilav
- Akihiro Yoshihara
- Akram Pourshams
- Ala'a Alkerwi
- Alain Morejon
- Albert Hofman
- Albertino Damasceno
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- Youchan Shin
- Young-Ho Khang
- Young-Ho Khang
- Yousef Saleh Khader
- Yufang Bi
- Yuki Fujita
- Yumi Cho
- Yuna He
- Yvonne T van der Schouw
- Zbigniew Gaciong
- Zbigniew Kulaga
- Zhengming Chen
- Zhengming Chen
- Ziad A Abdeen
- Publication venue
- ZU Scholars
- Publication date
- 01/01/2018
- Field of study
© The Author(s) 2018. Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20-29 years to 70-79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probittransformed) prevalence of raised blood pressure and age-group- and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure. Results: In 2005-16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the highincome Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association. Conclusions: Change in mean blood pressure is the main driver of the worldwide change in the prevalence of raised blood pressure, but change in the high-blood-pressure tail of the distribution has also contributed to the change in prevalence, especially in older age groups
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