176 research outputs found
One-step generation of high-quality squeezed and EPR states in cavity QED
We show how to generate bilinear (quadratic) Hamiltonians in cavity quantum
electrodynamics (QED) through the interaction of a single driven three-level
atom with two (one) cavity modes. With this scheme it is possible to generate
one-mode mesoscopic squeezed superpositions, two-mode entanglements, and
two-mode squeezed vacuum states (such the original EPR state), without the need
for Ramsey zones and external parametric amplification. The degree of squeezing
achieved is up to 99% with currently feasible experimental parameters and the
errors due to dissipative mechanisms become practically negligible
Leading-particle suppression in high energy nucleus-nucleus collisions
Parton energy loss effects in heavy-ion collisions are studied with the Monte
Carlo program PQM (Parton Quenching Model) constructed using the BDMPS
quenching weights and a realistic collision geometry. The merit of the approach
is that it contains only one free parameter that is tuned to the high-pt
nuclear modification factor measured in central Au-Au collisions at sqrt{s_NN}
= 200 GeV. Once tuned, the model is coherently applied to all the high-pt
observables at 200 GeV: the centrality evolution of the nuclear modification
factor, the suppression of the away-side jet-like correlations, and the
azimuthal anisotropies for these observables. Predictions for the
leading-particle suppression at nucleon-nucleon centre-of-mass energies of 62.4
and 5500 GeV are calculated. The limits of the eikonal approximation in the
BDMPS approach, when applied to finite-energy partons, are discussed.Comment: 28 pages, 14 figures, final version, accepted by Eur. Phys. J.
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
© 2019, The Author(s), under exclusive licence to Springer Nature America, Inc. To define the cell populations that drive joint inflammation in rheumatoid arthritis (RA), we applied single-cell RNA sequencing (scRNA-seq), mass cytometry, bulk RNA sequencing (RNA-seq) and flow cytometry to T cells, B cells, monocytes, and fibroblasts from 51 samples of synovial tissue from patients with RA or osteoarthritis (OA). Utilizing an integrated strategy based on canonical correlation analysis of 5,265 scRNA-seq profiles, we identified 18 unique cell populations. Combining mass cytometry and transcriptomics revealed cell states expanded in RA synovia: THY1(CD90) + HLA-DRA hi sublining fibroblasts, IL1B + pro-inflammatory monocytes, ITGAX + TBX21 + autoimmune-associated B cells and PDCD1 + peripheral helper T (T PH ) cells and follicular helper T (T FH ) cells. We defined distinct subsets of CD8 + T cells characterized by GZMK + , GZMB + , and GNLY + phenotypes. We mapped inflammatory mediators to their source cell populations; for example, we attributed IL6 expression to THY1 + HLA-DRA hi fibroblasts and IL1B production to pro-inflammatory monocytes. These populations are potentially key mediators of RA pathogenesis
International Journal of Chemical and Physical Sciences Binary Phase Diagramand Thin Film Coatings of Bimetallic Oxides using Bis(N-isopropylsalicylaldimine)M(II) M = Co, Ni and Zn as a Single Source Precursor for Thermal Chemical Vapor Deposition Binary
Abstract The metal Schiff base complexes of bis(N-isopropylsalicylaldimine)coblt(II), bis(N-isopropylsalicylaldimine)nickel(II) and bis (N-isopropylsalicylaldimine
Perineal Assessment and Repair Longitudinal Study (PEARLS): a matched-pair cluster randomized trial.
Perineal trauma during childbirth affects millions of women worldwide every year. The aim of the Perineal Assessment and Repair Longitudinal Study (PEARLS) was to improve maternal clinical outcomes following childbirth through an enhanced cascaded multiprofessional training program to support implementation of evidence-based perineal management
Elliptic flow of charged particles in Pb-Pb collisions at 2.76 TeV
We report the first measurement of charged particle elliptic flow in Pb-Pb
collisions at 2.76 TeV with the ALICE detector at the CERN Large Hadron
Collider. The measurement is performed in the central pseudorapidity region
(||<0.8) and transverse momentum range 0.2< < 5.0 GeV/. The
elliptic flow signal v, measured using the 4-particle correlation method,
averaged over transverse momentum and pseudorapidity is 0.087 0.002
(stat) 0.004 (syst) in the 40-50% centrality class. The differential
elliptic flow v reaches a maximum of 0.2 near = 3
GeV/. Compared to RHIC Au-Au collisions at 200 GeV, the elliptic flow
increases by about 30%. Some hydrodynamic model predictions which include
viscous corrections are in agreement with the observed increase.Comment: 10 pages, 4 captioned figures, published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/389
Measurement of D+- and D0 production in deep inelastic scattering using a lifetime tag at HERA
The production of D-+/-- and D-0-mesons has been measured with the ZEUS detector at HERA using an integrated luminosity of 133.6 pb(-1). The measurements cover the kinematic range 5 < Q(2) < 1000 GeV2, 0.02 < y < 0.7, 1.5 < p(T)(D) < 15 GeV and |eta(D)| < 1.6. Combinatorial background to the D-meson signals is reduced by using the ZEUS microvertex detector to reconstruct displaced secondary vertices. Production cross sections are compared with the predictions of next-to-leading-order QCD, which is found to describe the data well. Measurements are extrapolated to the full kinematic phase space in order to obtain the open-charm contribution, F-2(c (c) over bar), to the proton structure function, F-2
Planck Intermediate Results II: Comparison of Sunyaev–Zeldovich measurements from Planck and from the Arcminute Microkelvin Imager for 11 galaxy clusters
A comparison is presented of Sunyaev–Zeldovich measurements for 11 galaxy clusters as obtained by Planck and by the ground-based interferom- eter, the Arcminute Microkelvin Imager. Assuming a universal spherically-symmetric Generalised Navarro, Frenk & White (GNFW) model for the cluster gas pressure profile, we jointly constrain the integrated Compton-Y parameter (Y500) and the scale radius (θ500) of each cluster. Our resulting constraints in the Y500 − θ500 2D parameter space derived from the two instruments overlap significantly for eight of the clusters, although, overall, there is a tendency for AMI to find the Sunyaev–Zeldovich signal to be smaller in angular size and fainter than Planck. Significant discrepancies exist for the three remaining clusters in the sample, namely A1413, A1914, and the newly-discovered Planck cluster PLCKESZ G139.59+24.18. The robustness of the analysis of both the Planck and AMI data is demonstrated through the use of detailed simulations, which also discount confusion from residual point (radio) sources and from diffuse astrophysical foregrounds as possible explanations for the discrepancies found. For a subset of our cluster sample, we have investigated the dependence of our results on the assumed pressure profile by repeating the analysis adopting the best-fitting GNFW profile shape which best matches X-ray observations. Adopting the best-fitting profile shape from the X-ray data does not, in general, resolve the discrepancies found in this subset of five clusters. Though based on a small sample, our results suggest that the adopted GNFW model may not be sufficiently flexible to describe clusters universally
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