Structural and functional protein network analyses predict novel signaling functions for rhodopsin

Proteomic analyses, literature mining, and structural data were combined to generate an extensive signaling network linked to the visual G protein-coupled receptor rhodopsin. Network analysis suggests novel signaling routes to cytoskeleton dynamics and vesicular trafficking

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Determination of the strong coupling constant αs from transverse energy–energy correlations in multijet events at s√=8 TeV using the ATLAS detector

Measurements of transverse energy–energy correlations and their associated asymmetries in multi-jet events using the ATLAS detector at the LHC are presented. The data used correspond to s√=8 TeV proton–proton collisions with an integrated luminosity of 20.2 fb−1 . The results are presented in bins of the scalar sum of the transverse momenta of the two leading jets, unfolded to the particle level and compared to the predictions from Monte Carlo simulations. A comparison with next-to-leading-order perturbative QCD is also performed, showing excellent agreement within the uncertainties. From this comparison, the value of the strong coupling constant is extracted for different energy regimes, thus testing the running of αs(μ) predicted in QCD up to scales over 1 TeV . A global fit to the transverse energy–energy correlation distributions yields αs(mZ)=0.1162±0.0011(exp.) +0.0084−0.0070(theo.) , while a global fit to the asymmetry distributions yields a value of αs(mZ)=0.1196±0.0013(exp.) +0.0075−0.0045(theo.)

SINN-PROJEKTANT. O ZARZĄDZANIU SENSEM KULTUROWYM

W niniejszym artykule postaram się ukazać kulturę jako formę kompensacji dla współczesnego społeczeństwa. Zakładam, że zgadzamy się co do tego, iż nasze społeczeństwo jest skomplikowane w stopniu wymykający się spod kontroli, nasze technologie przytłaczają nas, a ludzkie normy nie dostarczają nam już orientacji w świecie. Kultura oferuje przeciwwagę dla tych skrajnych wymogów. Obiecuje ucieczkę od złożoności i oferuje nam symbole jedności

É preciso teologia para pensar o fim da História?

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Onde encontrar a diferença entre uma obra de arte e uma mercadoria?

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"In einer Welt der Simulation wird das Reale zur Obsession". Im Gespräch mit Norbert Bolz

Norbert Bolz, Jahrgang 1953, studierte Philosophie, Germanistik und Religionswissenschaft, promovierte zur Ästhetik Theodor Adornos und war Assistent des Berliner Religionsphilosophen Jacob Taubes. Habilitiert wurde er mit einer Arbeit zum philosophischen Extremismus der Weimarer Zeit, die unter dem Titel "Auszug aus der entzauberten Welt" erschien. Die Veröffentlichung des viel diskutierten Essays "Theorie der neuen Medien" (1990) markiert die Hinwendung zu anderen Themen und den Abschied von der traditionellen Philosophie: Norbert Bolz, der seit 1992 am Institut für Kunst- und Designwissenschaften in Essen lehrt, gehört heute zu den bekanntesten Medien- und Kommunikationstheoretikern im deutschsprachigen Raum. (...