Wrong Way Vehicle Detection in Single and Double Lane

Wrong-way driving is one of the primary causes of traffic jams and accidents globally. It is possible to identify vehicles going the wrong direction, which lessens accidents and traffic congestion. Surveillance footage has become an important source of data due to the accessibility of less priced cameras and the expanding use of real-time traffic management systems. In this paper, we propose a technique for automatically identifying automobiles moving against traffic. Our system uses the You Only Look Once (CNN) algorithm to recognize and track vehicles from video inputs and the centroid tracking method to determine each vehicle's orientation inside a given region of interest (ROI) in order to identify vehicles traveling in the wrong direction. It functions in three steps. The Deep sort tracking method is particularly good in detecting and tracking objects, and the centroid tracking technique can effectively monitor the direction of travel. Experiments with a variety of traffic films show that the suggested method can detect and identify wrong-way moving vehicles in a variety of lighting and weather scenarios. The interface of the system is quite simple and easy to use

Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions.

Colorectal cancer (CRC) accounts for ~9% of all cancers in the Veteran population, a fact which has focused a great deal of the attention of the VA\u27s research and development efforts. A field-based meeting of CRC experts was convened to discuss both challenges and opportunities in precision medicine for CRC. This group, designated as the VA Colorectal Cancer Cell-genomics Consortium (VA4C), discussed advances in CRC biology, biomarkers, and imaging for early detection and prevention. There was also a discussion of precision treatment involving fluorescence-guided surgery, targeted chemotherapies and immunotherapies, and personalized cancer treatment approaches. The overarching goal was to identify modalities that might ultimately lead to personalized cancer diagnosis and treatment. This review summarizes the findings of this VA field-based meeting, in which much of the current knowledge on CRC prescreening and treatment was discussed. It was concluded that there is a need and an opportunity to identify new targets for both the prevention of CRC and the development of effective therapies for advanced disease. Also, developing methods integrating genomic testing with tumoroid-based clinical drug response might lead to more accurate diagnosis and prognostication and more effective personalized treatment of CRC

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic

Peasants' Choices? Indian Agriculture and the Limits of Commercialization in Nineteenth-Century Bihar

The article attempts to distinguish and locate choices in agricultural production, with special reference to Bihar, India, during the nineteenth century. On the one hand, it considers closely managed and extensively irrigated areas, long involved in trade under the overall control of 'landlords', and, on the other hand, the expanding production of opium, and also of indigo and sugar (so-called 'forced' commercialization), identifying common features and continuities of production and marketing. Particular the importance of advance payments and local intermediaries is stressed. Thus, in contrast with the more usual evolutionary models, based on unitary categories and modes, the essay illustrates ecological, customary, collective, and local political constraints upon agricultural decisions; and this leads to the identification in turn of their different kinds and levels

Compositions and methods for modulating myeloid derived suppressor cells

Provided are methods and compositions for modulating the differentiation of a myeloid derived suppressor cell (MDSC). In particular, described herein are miR-142 polynucleotides and miR-223 polynucleotides that can be used to modulate differentiation of MDSCs. Increased differentiation of a MDSC population, or cells within an MDSC population, can be achieved by increasing the miR-142 and/or miR-223 polynucleotides in a MDSC

An approach to reduce the blindness burden in sub-Saharan Africa : special focus on childhood blindness

CITATION: Marmamula, S. et al. 2020. An approach to reduce the blindness burden in sub-Saharan Africa : special focus on childhood blindness, in Macnab, A., Daar, A. & Pauw, C. 2020. Health in transition : translating developmental origins of health and disease science to improve future health in Africa. Stellenbosch: SUN PReSS, doi:10.18820/9781928357759/13.The original publication is available at https://africansunmedia.store.it.si/zaSub-Saharan Africa is afflicted with high levels of blindness burden, affecting the quality of life and productivity of its people. While cataracts account for over 40 per cent of blindness, uncorrected refractive error leading to vision loss is over 50 per cent. The number of ophthalmologists and optometrists in the region, who can restore vision by surgery, and provide corrective eyeglasses for uncorrected refractive error, respectively, is woefully inadequate. However, most of these countries have primary health care centres. Workers in these centres have played remarkably successful roles in working with professionals in helping to reduce the burden of blindness due to onchocerciasis and trachoma.Publisher's versio