328 research outputs found
Development of a quick and reliable molecular detection system for Sclerotinia stem rot of canola in western Canada
Non-Peer ReviewedSclerotinia stem rot is an important, yield-limiting disease of canola caused by the necrotrophic fungus Sclerotinia sclerotiorum. The development of stem rot is highly dependent on environmental conditions and inoculum levels, and as a result disease occurrence and severity are sporadic in nature. In western Canada, stem rot is primarily controlled through the routine application of fungicides, which are often applied with no indication of disease risk. In order to reduce non-economical application of fungicides, a reliable forecasting system is needed. Since the infection of canola petals in an important step in the stem rot disease cycle, a quantitative (q)PCR-based system that can give an estimate of petal infestation rates could form the basis of a reliable forecasting system to help guide fungicide spray decisions. A primer and TaqMan probe have been developed based on the sequence of a novel protein that is specific to S. sclerotiorum. This primer-probe system, when used in a TaqMan qPCR assay, can quantify S. sclerotiorum DNA with a high level of sensitivity and specificity. The development of an internal amplification control will further increase the reliability of the assay by accounting for false negatives. This assay shows great potential for use as the basis of a stem rot forecasting system for canola in western Canada
Phase transitions in higher derivative gravity and gauge theory: R-charged black holes
This is a continuation of our earlier work where we constructed a
phenomenologically motivated effective action of the boundary gauge theory at
finite temperature and finite gauge coupling on . In this
paper, we argue that this effective action qualitatively reproduces the gauge
theory representing various bulk phases of R-charged black hole with
Gauss-Bonnet correction. We analyze the system both in canonical and grand
canonical ensemble.Comment: 36 pages, 16 figures; v2: typos corrected, references adde
Hagedorn divergences and tachyon potential
We consider the critical behavior for a string theory near the Hagedorn
temperature. We use the factorization of the worldsheet to isolate the Hagedorn
divergences at all genera. We show that the Hagedorn divergences can be
resummed by introducing double scaling limits, which smooth the divergences.
The double scaling limits also allow one to extract the effective potential for
the thermal scalar. For a string theory in an asymptotic anti-de Sitter (AdS)
spacetime, the AdS/CFT correspondence implies that the critical Hagedorn
behavior and the relation with the effective potential should also arise from
the boundary Yang-Mills theory. We show that this is indeed the case. In
particular we find that the free energy of a Yang-Mills theory contains
``vortex'' contributions at finite temperature. Yang-Mills Feynman diagrams
with vortices can be identified with contributions from boundaries of moduli
space on the string theory side.Comment: 36 pages, 13 figures, uses harvma
Does Solar Physics Provide Constraints to Weakly Interacting Massive Particles?
We investigate whether present data on helioseismology and solar neutrino
fluxes may constrain WIMP--matter interactions in the range of WIMP parameters
under current exploration in WIMP searches. We find that, for a WIMP mass of 30
GeV, once the effect of the presence of WIMPs in the Sun's interior is
maximized, the squared isothermal sound speed is modified, with respect to the
standard solar model, by at most 0.4% at the Sun's center. The maximal effect
on the Boron-8 solar neutrino flux is a reduction of 4.5%. Larger masses lead
to smaller effects. These results imply that present sensitivities in the
measurements of solar properties, though greatly improved in recent years, do
not provide information or constraints on WIMP properties of relevance for dark
matter. Furthermore, we show that, when current bounds from direct WIMP
searches are taken into account, the effect induced by WIMPs with dominant
coherent interactions are drastically reduced as compared to the values quoted
above. The case of neutralinos in the minimal supersymmetric standard model is
also discussed.Comment: 31 pages, 2 tables and 9 figures, typeset with ReVTeX4. The paper may
also be found at http://www.to.infn.it/~fornengo/papers/helio.ps.gz or
through http://www.to.infn.it/astropart/index.htm
Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at TeV
The elliptic, , triangular, , and quadrangular, , azimuthal
anisotropic flow coefficients are measured for unidentified charged particles,
pions and (anti-)protons in Pb-Pb collisions at TeV
with the ALICE detector at the Large Hadron Collider. Results obtained with the
event plane and four-particle cumulant methods are reported for the
pseudo-rapidity range at different collision centralities and as a
function of transverse momentum, , out to GeV/.
The observed non-zero elliptic and triangular flow depends only weakly on
transverse momentum for GeV/. The small dependence
of the difference between elliptic flow results obtained from the event plane
and four-particle cumulant methods suggests a common origin of flow
fluctuations up to GeV/. The magnitude of the (anti-)proton
elliptic and triangular flow is larger than that of pions out to at least
GeV/ indicating that the particle type dependence persists out
to high .Comment: 16 pages, 5 captioned figures, authors from page 11, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186
Centrality dependence of charged particle production at large transverse momentum in Pb-Pb collisions at TeV
The inclusive transverse momentum () distributions of primary
charged particles are measured in the pseudo-rapidity range as a
function of event centrality in Pb-Pb collisions at
TeV with ALICE at the LHC. The data are presented in the range
GeV/ for nine centrality intervals from 70-80% to 0-5%.
The Pb-Pb spectra are presented in terms of the nuclear modification factor
using a pp reference spectrum measured at the same collision
energy. We observe that the suppression of high- particles strongly
depends on event centrality. In central collisions (0-5%) the yield is most
suppressed with at -7 GeV/. Above
GeV/, there is a significant rise in the nuclear modification
factor, which reaches for GeV/. In
peripheral collisions (70-80%), the suppression is weaker with almost independently of . The measured nuclear
modification factors are compared to other measurements and model calculations.Comment: 17 pages, 4 captioned figures, 2 tables, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/284
Measurement of charm production at central rapidity in proton-proton collisions at TeV
The -differential production cross sections of the prompt (B
feed-down subtracted) charmed mesons D, D, and D in the rapidity
range , and for transverse momentum GeV/, were
measured in proton-proton collisions at TeV with the ALICE
detector at the Large Hadron Collider. The analysis exploited the hadronic
decays DK, DK, DD, and their charge conjugates, and was performed on a
nb event sample collected in 2011 with a
minimum-bias trigger. The total charm production cross section at TeV and at 7 TeV was evaluated by extrapolating to the full phase space
the -differential production cross sections at TeV
and our previous measurements at TeV. The results were compared
to existing measurements and to perturbative-QCD calculations. The fraction of
cdbar D mesons produced in a vector state was also determined.Comment: 20 pages, 5 captioned figures, 4 tables, authors from page 15,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/307
Particle-yield modification in jet-like azimuthal di-hadron correlations in Pb-Pb collisions at = 2.76 TeV
The yield of charged particles associated with high- trigger
particles ( GeV/) is measured with the ALICE detector in
Pb-Pb collisions at = 2.76 TeV relative to proton-proton
collisions at the same energy. The conditional per-trigger yields are extracted
from the narrow jet-like correlation peaks in azimuthal di-hadron correlations.
In the 5% most central collisions, we observe that the yield of associated
charged particles with transverse momenta GeV/ on the
away-side drops to about 60% of that observed in pp collisions, while on the
near-side a moderate enhancement of 20-30% is found.Comment: 15 pages, 2 captioned figures, 1 table, authors from page 10,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/350
Effect of cross-linked biodegradable polymers on sustained release of sodium diclofenac-loaded microspheres
Tracking development assistance for health and for COVID-19 : a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050
Background The rapid spread of COVID-19 renewed the focus on how health systems across the globe are financed, especially during public health emergencies. Development assistance is an important source of health financing in many low-income countries, yet little is known about how much of this funding was disbursed for COVID-19. We aimed to put development assistance for health for COVID-19 in the context of broader trends in global health financing, and to estimate total health spending from 1995 to 2050 and development assistance for COVID-19 in 2020. Methods We estimated domestic health spending and development assistance for health to generate total health-sector spending estimates for 204 countries and territories. We leveraged data from the WHO Global Health Expenditure Database to produce estimates of domestic health spending. To generate estimates for development assistance for health, we relied on project-level disbursement data from the major international development agencies' online databases and annual financial statements and reports for information on income sources. To adjust our estimates for 2020 to include disbursements related to COVID-19, we extracted project data on commitments and disbursements from a broader set of databases (because not all of the data sources used to estimate the historical series extend to 2020), including the UN Office of Humanitarian Assistance Financial Tracking Service and the International Aid Transparency Initiative. We reported all the historic and future spending estimates in inflation-adjusted 2020 US per capita, purchasing-power parity-adjusted US8. 8 trillion (95% uncertainty interval [UI] 8.7-8.8) or 40.4 billion (0.5%, 95% UI 0.5-0.5) was development assistance for health provided to low-income and middle-income countries, which made up 24.6% (UI 24.0-25.1) of total spending in low-income countries. We estimate that 13.7 billion was targeted toward the COVID-19 health response. 1.4 billion was repurposed from existing health projects. 2.4 billion (17.9%) was for supply chain and logistics. Only 1519 (1448-1591) per person in 2050, although spending across countries is expected to remain varied. Interpretation Global health spending is expected to continue to grow, but remain unequally distributed between countries. We estimate that development organisations substantially increased the amount of development assistance for health provided in 2020. Continued efforts are needed to raise sufficient resources to mitigate the pandemic for the most vulnerable, and to help curtail the pandemic for all. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe
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