Studies on Schistosomiasis. 9. Pathology of the bovine urinary tract

Pathological findings in the urinary tract of 40 head of cattle, experimentally or naturally infested with Schistosoma mattheei, are presented. Lesions of the ureter found in 57,5% of the cases consisted of linear granulomata with associated haemorrhages or granular patches. The segmental hydro-ureter caused by disruption of the muscular tunic by a granular patch type of lesion was a prominent finding. Bilharzial bladder lesions observed in 75% of the animals were of 4 distinct types: granulomatous foci 1-2 mm in diameter, granular patches, polypoid patches and polyps. In all cases with bladder lesions the fundus was affected; neck and trigonal lesions tended to occur in the more severely affected bladders. The Hoeppli phenomenon was more common than in other species and was associated with the subacute stage of lesion. Urinary bladders with ovum granulomata: throughout the lamina had more severe microscopic lesions than those with ovum granulomata in the submucosa only. The stage of development of the bladder lesion was related directly to the length of infestation of the animal. There was an inverse ratio between the percentage of live ova in the bladders and increased chronicity of the lesions. Since the effects of reinfestation on the pathology were quantitative, a larger percentage of the reinfested animals had bladder and ureteric lesions, which tended to be more severe and, in the bladder, more chronic than in singly infested animals. A significant rank correlation was observed between the W-D index (relating the worm burdens and the duration of infestation) and the severity of macroscopic and microscopic bladder lesions (P< 0,001). The duration of infestation and the W-D index were significantly greater in animals with bladder lesions than in those without (P< 0,000 1) and no lesions of the bladders and ureters were found in animals infested less than 185 days, indicating an extended prepatent period in bovine urinary schistosomiasis. On the other hand, there were no significant differences between the worm burdens of animals with or without bladder lesions, suggesting that the first lesions appear between 70 and 185 days after infestation, regardless of the number of worms present. Possible migration routes to the urinary tract are discussed. The bilharzial granulomata observed in the renal pelvis of 20% of the animals is the first reported incidence of bilharzial lesions of the renal pelvis. The incidence of renal parenchymal lesions in infested animals was more than double that in uninfested controls.The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

Vitamin A deficiency in the captive African lion cub, Panthera leo (Linnaeus, 1758)

Dietary, breeding and clinical histories and pathological findings are presented from 2 confirmed and 5 presumed cases of vitamin A deficiency in immature African lions. Five of the 7 animals were born in the wild while 2 were born in captivity. All animals were fed lean red meat sprinkled with a vitamin/mineral supplement. Salient clinical signs were incoordination, "star gazing", blindness and intermittent convulsions. Pathological lesions seen in 4 animals included severe thickening of the cranial bones, with consequent marked compression of the brain and partial herniation of the cerebellum. Vascular damage in the cerebellum and ensuing haemorrhages, resulting in acute increases of an already high intracranial pressure, were thought to be the cause of some of the clinical signs, particularly convulsions rather than direct pressure-necrosis and atrophy of nervous tissueThe articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acroabt XI was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

Studies on schistosomiasis. 6. A field outbreak of bilharzia in cattle

An outbreak of bilharzia (Schistosoma mattheei) infestation involving about 100 oxen on the farm Otthilie near Tolwe in northern Transvaal is described. Infestation of the cattle appears to have occurred per os from a single drinking trough. The cattle showed clinical signs and pathological lesions of both the reinfestation and the acute syndromes. The worm burdens were the highest recorded hitherto in naturally infested cattle. Severe macroscopic clay pipe stem periportal fibrosis, granulomata of the ureters and severe grey pigmentation of the lungs, are described for the first time in naturally infested cattle. There was more marked liver pigmentation than had been encountered previously in this host. A striking feature in every case was conspicuous congestion and enlargement of the ileo-cecal valve, which was dark red in colour. Treatment of affected animals with injectable trichlorphon controlled the outbreak without causing mass embolism and liver infarcts. At least 11 treatments at a dosage level of 10-12 mg/kg per treatment at 3-5 day intervals are necessary. Faecal examinations for eggs or miracidia cannot be used to assess the worm burden or the clinical state of the animal. Moreover, it is suggested that this disease may be confused with other conditions and this probably accounts for the rarity of reports of outbreaks in ruminants.The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

Global Search for New Physics with 2.0/fb at CDF

Data collected in Run II of the Fermilab Tevatron are searched for indications of new electroweak-scale physics. Rather than focusing on particular new physics scenarios, CDF data are analyzed for discrepancies with the standard model prediction. A model-independent approach (Vista) considers gross features of the data, and is sensitive to new large cross-section physics. Further sensitivity to new physics is provided by two additional algorithms: a Bump Hunter searches invariant mass distributions for "bumps" that could indicate resonant production of new particles; and the Sleuth procedure scans for data excesses at large summed transverse momentum. This combined global search for new physics in 2.0/fb of ppbar collisions at sqrt(s)=1.96 TeV reveals no indication of physics beyond the standard model.Comment: 8 pages, 7 figures. Final version which appeared in Physical Review D Rapid Communication

Observation of Orbitally Excited B_s Mesons

We report the first observation of two narrow resonances consistent with states of orbitally excited (L=1) B_s mesons using 1 fb^{-1} of ppbar collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. We use two-body decays into K^- and B^+ mesons reconstructed as B^+ \to J/\psi K^+, J/\psi \to \mu^+ \mu^- or B^+ \to \bar{D}^0 \pi^+, \bar{D}^0 \to K^+ \pi^-. We deduce the masses of the two states to be m(B_{s1}) = 5829.4 +- 0.7 MeV/c^2 and m(B_{s2}^*) = 5839.7 +- 0.7 MeV/c^2.Comment: Version accepted and published by Phys. Rev. Let

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters

Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio

Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS

The chi_b(nP) quarkonium states are produced in proton-proton collisions at the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS detector. Using a data sample corresponding to an integrated luminosity of 4.4 fb^-1, these states are reconstructed through their radiative decays to Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes. This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table, corrected author list, matches final version in Physical Review Letter

Measurement of the inclusive isolated prompt photon cross-section in pp collisions at sqrt(s)= 7 TeV using 35 pb-1 of ATLAS data

A measurement of the differential cross-section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy sqrt(s) = 7 TeV is presented. The measurement covers the pseudorapidity ranges |eta|<1.37 and 1.52<=|eta|<2.37 in the transverse energy range 45<=E_T<400GeV. The results are based on an integrated luminosity of 35 pb-1, collected with the ATLAS detector at the LHC. The yields of the signal photons are measured using a data-driven technique, based on the observed distribution of the hadronic energy in a narrow cone around the photon candidate and the photon selection criteria. The results are compared with next-to-leading order perturbative QCD calculations and found to be in good agreement over four orders of magnitude in cross-section.Comment: 7 pages plus author list (18 pages total), 2 figures, 4 tables, final version published in Physics Letters

Reducing heterotic M-theory to five dimensional supergravity on a manifold with boundary

This paper constructs the reduction of heterotic $M$-theory in eleven dimensions to a supergravity model on a manifold with boundary in five dimensions using a Calabi-Yau three-fold. New results are presented for the boundary terms in the action and for the boundary conditions on the bulk fields. Some general features of dualisation on a manifold with boundary are used to explain the origin of some topological terms in the action. The effect of gaugino condensation on the fermion boundary conditions leads to a `twist' in the chirality of the gravitino which can provide an uplifting mechanism in the vacuum energy to cancel the cosmological constant after moduli stabilisation.Comment: 16 pages, RevTe