83 research outputs found
Coexistence of HBsAg/Anti-HBs and HBeAg/Anti-HBe in Sudanese Patients with Chronic Hepatitis B Virus Infection: A Cross-Sectional Study
- Author
- Publication venue
- International Medical Research and Development Corporation
- Publication date
- 01/12/2023
- Field of study
Background: Seroconversion of hepatitis B surface antigen (HBsAg) to hepatitis B surface antibody (anti-HBs) is a recognized goal of HBV therapy. This dynamic transition responsible for the coexistence of HBsAg and anti-HBs is rarely detected in clinical cases. However, with vaccination and the use of various antiviral drugs, as well as the development of new medical technologies, recognizing the coexistence of HBsAg and anti-HBs has become more common. In addition, mutations in viral genomes, immune status, and human genetic factors may also contribute to such coexistence. The current study was designed to determine the prevalence of the coexistence of HBsAg and anti-HBs and HBeAg and anti-HBe in CHB patients in Sudan.
Methods and Results: This was a descriptive cross-sectional study conducted in Khartoum state from November 2018 to January 2019. The study included 70 HBV-infected patients who were positive for HBsAg for more than six months. Blood samples were tested for HBsAg/Anti-HBs and HBeAg/Anti-HBe using Commercial ELISA Kits (Foresight, United Kingdom) and (PRECHEK, USA). Demographic data were collected using a structured questionnaire, and any antiviral agent and laboratory results were also recorded for each participant. The current study showed that one case (1.4%) was reactive for the coexistence of HBsAg/HBsAb and two cases (2.8%) for the coexistence of HBeAg/HBeAb. There was no statistical difference between the coexistence of HBsAg/HBsAb and HBeAg/HBeAb with age, gender, residence, and treatment status.
Conclusion: Our study indicates that the frequencies of the coexistence of HBsAg/HBsAb and HBeAg/HBeAb among Sudanese patients with chronic HBV infection were low compared to previous studies in a different population
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
- Author
- A M. P.
- Abbas J.
- Abbasi N.
- Abbastabar H.
- Abreu L. G.
- Abu-Gharbieh E.
- Achappa B.
- Adabi M.
- Adal T. G.
- Adegbosin A. E.
- Adekanmbi V.
- Adetokunboh O. O.
- Agudelo-Botero M.
- Ahinkorah B. O.
- Ahmadi K.
- Ahmed M. B.
- Alhassan R. K.
- Alipour V.
- Almasi-Hashiani A.
- Alvis-Guzman N.
- Amin H. I. M.
- Ancuceanu R.
- Andrei T.
- Anvari D.
- Aqeel M.
- Arabloo J.
- Aremu O.
- Arnedo C. A. M.
- Asaad M.
- Atnafu D. D.
- Atreya A.
- Azari S.
- B D. B.
- Baig A. A.
- Banach M.
- Bante S. A.
- Barboza M. A.
- Basu S.
- Baumann M.
- Bedi N.
- Bensenor I. M.
- Beyene F. -H. Y.
- Bezabih Y. M.
- Bhagavathula A. S.
- Bhardwaj N.
- Bhardwaj P.
- Bhattacharyya K.
- Bhutta Z. A.
- Bijani A.
- Birlik S. M.
- Bitew Z. W.
- Bohlouli S.
- Boloor A.
- Brunoni A. R.
- Butt Z. A.
- Cardenas R.
- Carvalho F.
- Casta-neda-orjuela C. A.
- Castaldelli-Maia J. M.
- Charan J.
- Chatterjee S.
- Chattu S. K.
- Chattu V. K.
- Chowdhury M. A. K.
- Christopher D. J.
- Chu D. -T.
- Cook A. J.
- Cork M. A.
- Cormier N. M.
- Croneberger A. J.
- Dahlawi S. M. A.
- Daoud F.
- Davila-Cervantes C. A.
- De la Hoz F. P.
- Defo B. K.
- Demeke F. M.
- Denova-Gutierrez E.
- Deribe K.
- Deuba K.
- Dharmaratne S. D.
- Dhungana G. P.
- Diaz D.
- Djalalinia S.
- Duraes A. R.
- Dwyer-Lindgren L.
- Eagan A. W.
- Earl L.
- Effiong A.
- El-Jaafary S. I.
- Elayedath R.
- Faraon E. J. A.
- Faro A.
- Fattahi N.
- Fauk N. K.
- Fernandes E.
- Filip I.
- Fischer F.
- Foigt N. A.
- Foroutan M.
- Fukumoto T.
- Gad M. M.
- Gebremariam T. B. B.
- Gebremed-Hin K. B.
- Gebremeskel G. G.
- Gesesew H. A.
- Ghadiri K.
- Ghashghaee A.
- Gilani S. A.
- Golechha M.
- Gori U.
- Goulart A. C.
- Goulart B. N. G.
- Gugnani H. C.
- Guimaraes M. D. C.
- Guimaraes R. A.
- Guo Y. -I.
- Gupta R.
- Haeuser E.
- Haider M. R.
- Haile T. G.
- Haj-Mirzaian A.
- Haj-Mirzaian A.
- Hanif A.
- Hargono A.
- Hariyani N.
- Hassanipour S.
- Hassankhani H.
- Hay S. I.
- Hayat K.
- Henry N. J.
- Herteliu C.
- Ho H. C.
- Holla R.
- Hosseinzadeh M.
- Househ M.
- Hwang B. -F.
- Ibeneme C. U.
- Ibitoye S. E.
- Ile-Sanmi O. S.
- Ilic I. M.
- Ilic M. D.
- Iqbal U.
- Jahagir-Dar D.
- Jain V.
- Jakovljevic M.
- Jha R. P.
- Johnson K. B.
- Joseph N.
- Joukar F.
- Kalankesh L. R.
- Kalhor R. -L.
- Kanchan T.
- Karch A.
- Karimi S. E.
- Karyani A. K.
- Kassahun G.
- Kayode G. A.
- Keramati M.
- Khalid N.
- Khan E. A.
- Khan G.
- Khan M. N. N.
- Khaneghah A. M. -S.
- Khatab K.
- Kianipour N.
- Kim Y. J.
- Kisa A.
- Kisa S.
- Kosen S.
- Koyanagi A.
- Krishan K.
- Kuchenbecker R. S.
- Kulkarni V.
- Kumar M.
- Kumar N.
- Kurmi O. P.
- Kusuma D.
- Lal D. K.
- Landires I.
- Lasrado S.
- Laxminarayana S. L. K.
- Lee P. H.
- Legrand K. E.
- Letourneau I. D.
- Li B.
- Li S.
- Liu X.
- Machado D. B.
- Madi D.
- Magis-Rodriguez C.
- Malta D. C.
- Mansournia M. A.
- Manzar M. D.
- Martins-Melo F. R.
- Masoumi S. Z.
- Matin B. K.
- Mayala B. K.
- Medina-Solis C. E.
- Memish Z. A.
- Mendoza W.
- Menezes R. G.
- Mestrovic T.
- Mezerji N. M. G.
- Mirica A.
- Moazen B.
- Mohammad Y.
- Mohammadian-Hafshejani A.
- Mohammadpourhodki R.
- Mohammed S.
- Mokdad A. H.
- Moni M. A.
- Moradi M.
- Moradi Y.
- Moradzadeh R.
- Moraga P.
- Mustafa G.
- Mwanri L.
- Nagaraja R.
- Nagarajan A. J.
- Naim-Zada M. D.
- Nascimento B. R.
- Naveed D. M.
- Nayak V. C.
- Nazari J.
- Negash H.
- Negoi I.
- Nepal S.
- Nguefack-Tsague G.
- Nguyen C. T.
- Nguyen H. L. T.
- Nikbakhsh R.
- Noubiap J. J.
- Nunez-Samudio V.
- Oancea B.
- Ogbo F. A.
- Olagunju A. T.
- Otstav-Nov N.
- Padubidri J. R.
- Pandi-Perumal S. R.
- Pardo-Montano A. M.
- Patel U. K.
- Pawar S.
- Peprah E. K.
- Pereira A.
- Perkins S.
- Pescarini J. M.
- Pokhrel K. N.
- Postma M. J.
- Pot-Too F. H.
- Prada S. I.
- Preotescu L.
- Pribadi D. R. A.
- Quintanilla B. P. A.
- Radfar A.
- Rahim F.
- Rahman M. H. U.
- Rahmani A. M.
- Ramezanzadeh K.
- Ramirez D. F. B.
- Rana J.
- Ranabhat C. L.
- Rao S. J.
- Rathi P.
- Rawaf D. L.
- Rawaf S.
- Rawassizadeh R.
- Renjith V.
- Rezaei N.
- Rezapour A.
- Ribeiro A. I.
- Roever L.
- Rubagotti E.
- Rumisha S. F.
- Rwegerera G. M.
- Sagar R.
- Sajadi S. M.
- Salem M. R.
- Samy A. M.
- Sarmiento-Suarez R.
- Sathian B.
- Schaeffer L. E.
- Schneider I. J. C.
- Seidu A. -A.
- Serfes A. L.
- Sha F.
- Shaikh M. A.
- Sharafi K. -M.
- Sheikh A.
- Shibuya K.
- Shin J. I.
- Silva D. A. S.
- Singh J. A.
- Skryabin V. Y.
- Skryabina A. A.
- Sligar A.
- Soheili A.
- Steuben K. M.
- Sufiyan M. B.
- Tadesse E. G.
- Tantawi M. E.
- Tesema A. K. T.
- Tesfay F. H.
- Thapar R.
- Thompson R. L.
- Tovani-Palone M. R.
- Tran B. X.
- Tsegaye G. W.
- Umeokonkwo C. D.
- Unnikrish-Nan B.
- Vasseghian Y.
- Vecchia C. L.
- Violante F. S.
- Vo B.
- Vu G. T.
- Waheed Y.
- Wang Y.
- Wang Y. -P.
- Ward P.
- Watson S.
- Weaver N. D.
- Welay F. T.
- Westerman R.
- Wickramasinghe N. D.
- Yang M.
- Yaya S.
- Yip P.
- Yonemoto N.
- Yu C.
- Yuce D.
- Yusefzadeh H.
- Zaki M. E. S.
- Zamanian M.
- Zastroz-Hin M. S.
- Zhang Y.
- Zhang Z. -J.
- Ziapour A.
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background: Human immunodeficiency virus (HIV) remains a public health priority in Latin America. While the burden of HIV is historically concentrated in urban areas and high-risk groups, subnational estimates that cover multiple countries and years are missing. This paucity is partially due to incomplete vital registration (VR) systems and statistical challenges related to estimating mortality rates in areas with low numbers of HIV deaths. In this analysis, we address this gap and provide novel estimates of the HIV mortality rate and the number of HIV deaths by age group, sex, and municipality in Brazil, Colombia, Costa Rica, Ecuador, Guatemala, and Mexico. Methods: We performed an ecological study using VR data ranging from 2000 to 2017, dependent on individual country data availability. We modeled HIV mortality using a Bayesian spatially explicit mixed-effects regression model that incorporates prior information on VR completeness. We calibrated our results to the Global Burden of Disease Study 2017. Results: All countries displayed over a 40-fold difference in HIV mortality between municipalities with the highest and lowest age-standardized HIV mortality rate in the last year of study for men, and over a 20-fold difference for women. Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. In all six countries included in this analysis, 50% or more HIV deaths were concentrated in fewer than 10% of municipalities in the latest year of study. In addition, national age patterns reflected shifts in mortality to older age groups—the median age group among decedents ranged from 30 to 45 years of age at the municipality level in Brazil, Colombia, and Mexico in 2017. Conclusions: Our subnational estimates of HIV mortality revealed significant spatial variation and diverging local trends in HIV mortality over time and by age. This analysis provides a framework for incorporating data and uncertainty from incomplete VR systems and can help guide more geographically precise public health intervention to support HIV-related care and reduce HIV-related deaths
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
- Author
- A Castañeda-Orjuela C.
- A Dávila-Cervantes C.
- A Guimarães R.
- A Marrugo Arnedo C.
- A S Silva D.
- Abbas J.
- Abbasi N.
- Abbastabar H.
- Abreu L.G.
- Abu-Gharbieh E.
- Achappa B.
- Adabi M.
- Adal T.G.
- Adegbosin A.E.
- Adekanmbi V.
- Adetokunboh O.O.
- Agudelo-Botero M.
- Ahinkorah B.O.
- Ahmadi K.
- Ahmed M.B.
- Ahsanul Kabir Chowdhury M.
- Alhassan R.K.
- Alipour V.
- Almasi-Hashiani A.
- Alvis-Guzman N.
- Ancuceanu R.
- Andrei T.
- Anvari D.
- Aqeel M.
- Arabloo J.
- Aremu O.
- Asaad M.
- Atnafu D.D.
- Atreya A.
- Azari S.
- B B Gebremariam T.
- B B D.
- Baig A.A.
- Banach M.
- Bante S.A.
- Barboza M.A.
- Basu S.
- Baumann M.
- Bedi N.
- Bensenor I.M.
- Beyene F.Y.
- Bezabih Y.M.
- Bhagavathula A.S.
- Bhardwaj N.
- Bhardwaj P.
- Bhattacharyya K.
- Bhutta Z.A.
- Bijani A.
- Birlik S.M.
- Bitew Z.W.
- Bohlouli S.
- Boloor A.
- Brunoni A.R.
- Butt Z.A.
- Carvalho F.
- Charan J.
- Chatterjee S.
- Chattu S.K.
- Chattu V.K.
- Christopher D.J.
- Chu D.-T.
- Cook A.J.
- Cork M.A.
- Cormier N.M.
- Croneberger A.J.
- Cárdenas R.
- D C Guimaraes M.
- Daoud F.
- Defo B.K.
- Demeke F.M.
- Denova-Gutiérrez E.
- Deribe K.
- Deuba K.
- Dharmaratne S.D.
- Dhungana G.P.
- Diaz D.
- Djalalinia S.
- Duraes A.R.
- Dwyer-Lindgren L.
- E Medina-SolÃs C.
- Eagan A.W.
- Earl L.
- Effiong A.
- El Sayed Zaki M.
- Elayedath R.
- F Bejarano Ramirez D.
- Faro A.
- Fattahi N.
- Fauk N.K.
- Fernandes E.
- Filip I.
- Fischer F.
- Foigt N.A.
- Foroutan M.
- Fukumoto T.
- Gad M.M.
- Gebremedhin K.B.
- Gebremeskel G.G.
- Gesesew H.A.
- Ghadiri K.
- Ghashghaee A.
- Gilani S.A.
- Golechha M.
- Gori U.
- Goulart A.C.
- Goulart B.N.G.
- Gugnani H.C.
- Guo Y.
- Gupta R.
- Haeuser E.
- Haider M.R.
- Haile T.G.
- Haj-Mirzaian A.
- Haj-Mirzaian A.
- Hanif A.
- Hargono A.
- Hariyani N.
- Hassanipour S.
- Hassankhani H.
- Hay S.I.
- Hayat K.
- Henry N.J.
- Herteliu C.
- Hifz Ur Rahman M.
- Ho H.C.
- Holla R.
- Hosseinzadeh M.
- Househ M.
- Hwang B.-F.
- I El-Jaafary S.
- I M. Amin H.
- Ibeneme C.U.
- Ibitoye S.E.
- Ilesanmi O.S.
- Ilic I.M.
- Ilic M.D.
- Iqbal U.
- J C Schneider I.
- Jahagirdar D.
- Jain V.
- Jakovljevic M.
- Jha R.P.
- Johnson K.B.
- Jose A Faraon E.
- Joseph N.
- Joukar F.
- K T Tesema A.
- Kalankesh L.R.
- Kalhor R.
- Kanchan T.
- Karch A.
- Karimi S.E.
- Karyani A.K.
- Kassahun G.
- Kayode G.A.
- Keramati M.
- Khalid N.
- Khan E.A.
- Khan G.
- Khaneghah A.M.
- Khatab K.
- Kianipour N.
- Kim Y.J.
- Kisa A.
- Kisa S.
- Kosen S.
- Koyanagi A.
- Krishan K.
- Kuchenbecker R.S.
- Kulkarni V.
- Kumar M.
- Kumar N.
- Kurmi O.P.
- Kusuma D.
- L T Nguyen H.
- Lakshmi Koulmane Laxminarayana S.
- Lal D.K.
- Landires I.
- Lasrado S.
- Lee P.H.
- LeGrand K.E.
- Letourneau I.D.
- Li B.
- Li S.
- Liu X.
- M A Dahlawi S.
- M Pardo-Montaño A.
- Machado D.B.
- Madi D.
- Magis-Rodriguez C.
- Malta D.C.
- Mansournia M.A.
- Manzar M.D.
- Masoumi S.Z.
- Matin B.K.
- Mauricio Castaldelli-Maia J.
- Mayala B.K.
- Memish Z.A.
- Mendoza W.
- Menezes R.G.
- Mestrovic T.
- Mirica A.
- Moazen B.
- Mohammad Gholi Mezerji N.
- Mohammad Y.
- Mohammadian-Hafshejani A.
- Mohammadpourhodki R.
- Mohammed S.
- Mokdad A.H.
- Moni M.A.
- Moradi M.
- Moradi Y.
- Moradzadeh R.
- Moraga P.
- Mustafa G.
- Mwanri L.
- Nagaraja R.
- Nagarajan A.J.
- Naimzada M.D.
- Nascimento B.R.
- Naveed D.M.
- Nayak V.C.
- Nazari J.
- Negash H.
- Negoi I.
- Nepal S.
- Nguefack-Tsague G.
- Nguyen C.T.
- Nikbakhsh R.
- Noubiap J.J.
- Nunez-Samudio V.
- Nuruzzaman N Khan M.
- Oancea B.
- of Disease HIV Collaborators Local Burden
- Ogbo F.A.
- Olagunju A.T.
- Otstavnov N.
- P A M.
- P De la Hoz F.
- Padubidri J.R.
- Patel U.K.
- Paulina Ayala Quintanilla B.
- Pawar S.
- Peprah E.K.
- Pereira A.
- Perkins S.
- Pescarini J.M.
- Pokhrel K.N.
- Postma M.J.
- Pottoo F.H.
- Prada S.I.
- Preotescu L.
- R A Pribadi D.
- R Martins-Melo F.
- R Pandi-Perumal S.
- R Tovani-Palone M.
- Radfar A.
- Rahim F.
- Rahmani A.M.
- Ramezanzadeh K.
- Rana J.
- Ranabhat C.L.
- Rao S.J.
- Rathi P.
- Rawaf D.L.
- Rawaf S.
- Rawassizadeh R.
- Renjith V.
- Rezaei N.
- Rezapour A.
- Ribeiro A.I.
- Roever L.
- Rubagotti E.
- Rumisha S.F.
- Rwegerera G.M.
- Sagar R.
- Sajadi S.M.
- Salem M.R.
- Samy A.M.
- Sarmiento-Suárez R.
- Sathian B.
- Schaeffer L.E.
- Seidu A.-A.
- Serfes A.L.
- Sha F.
- Shaikh M.A.
- Sharafi K.
- Sheikh A.
- Shibuya K.
- Shin J.I.
- Singh J.A.
- Skryabin V.Y.
- Skryabina A.A.
- Sligar A.
- Soheili A.
- Steuben K.M.
- Sufiyan M.B.
- Tadesse E.G.
- Tantawi M.E.
- Tesfay F.H.
- Thapar R.
- Thompson R.L.
- Tran B.X.
- Tsegaye G.W.
- Umeokonkwo C.D.
- Unnikrishnan B.
- Vasseghian Y.
- Vecchia C.L.
- Violante F.S.
- Vo B.
- Vu G.T.
- Waheed Y.
- Wang Y.
- Wang Y.-P.
- Ward P.
- Watson S.
- Weaver N.D.
- Welay F.T.
- Westerman R.
- Wickramasinghe N.D.
- Yang M.
- Yaya S.
- Yip P.
- Yonemoto N.
- Yu C.
- Yuce D.
- Yusefzadeh H.
- Zamanian M.
- Zastrozhin M.S.
- Zhang Y.
- Zhang Z.-J.
- Ziapour A.
- Publication venue
- Publication date
- 27/11/2020
- Field of study
BackgroundHuman immunodeficiency virus (HIV) remains a public health priority in Latin America. While the burden of HIV is historically concentrated in urban areas and high-risk groups, subnational estimates that cover multiple countries and years are missing. This paucity is partially due to incomplete vital registration (VR) systems and statistical challenges related to estimating mortality rates in areas with low numbers of HIV deaths. In this analysis, we address this gap and provide novel estimates of the HIV mortality rate and the number of HIV deaths by age group, sex, and municipality in Brazil, Colombia, Costa Rica, Ecuador, Guatemala, and Mexico.MethodsWe performed an ecological study using VR data ranging from 2000 to 2017, dependent on individual country data availability. We modeled HIV mortality using a Bayesian spatially explicit mixed-effects regression model that incorporates prior information on VR completeness. We calibrated our results to the Global Burden of Disease Study 2017.ResultsAll countries displayed over a 40-fold difference in HIV mortality between municipalities with the highest and lowest age-standardized HIV mortality rate in the last year of study for men, and over a 20-fold difference for women. Despite decreases in national HIV mortality in all countries-apart from Ecuador-across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. In all six countries included in this analysis, 50% or more HIV deaths were concentrated in fewer than 10% of municipalities in the latest year of study. In addition, national age patterns reflected shifts in mortality to older age groups-the median age group among decedents ranged from 30 to 45years of age at the municipality level in Brazil, Colombia, and Mexico in 2017.ConclusionsOur subnational estimates of HIV mortality revealed significant spatial variation and diverging local trends in HIV mortality over time and by age. This analysis provides a framework for incorporating data and uncertainty from incomplete VR systems and can help guide more geographically precise public health intervention to support HIV-related care and reduce HIV-related deaths.Peer reviewe
Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.
- Author
- Aawsaj Y.
- Abad Gurumeta A.
- Abad-Motos A.
- Abate E.
- Abatini C.
- Abbadessa F.
- Abbas A. M.
- Abbassi-Ghadi N.
- Abbott D.
- Abbott T.
- Abd Elazeem H. A. S.
- Abdalla M.
- Abdallah M.
- Abdel Al S.
- Abdel Jalil R.
- Abdeldayem H.
- Abdelkader Salama I.
- Abdelkarem M. M.
- Abdelkarim M.
- Abdelmajeed A.
- Abdelrahman A.
- Abdelrahman S.
- Abdelsamed A.
- Abdou M.
- Abdulkareem A.
- Abdulwahed E.
- Abdur-Rahman L.
- Abel M. K.
- Abellan M.
- Aboelkassem Ibrahim A.
- Abosamak N. E.
- Abou Chaar M. K.
- Abou-Khalil J.
- Abouassi A.
- Aboulkassem H.
- Abreu Da Silva A.
- Abu J.
- Abu Za'nouneh F. J.
- Abu-Nayla I.
- Abubakar A.
- Acebes Garcia F.
- Achalandabaso Boira M.
- Acher A.
- Acrich E.
- Adamina M.
- Adamoli L.
- Addae-Boateng E.
- Aderombi A.
- Adeyeye A.
- Adiamah A.
- Adishesh M.
- Agapov M.
- Aggarwal A.
- Aghayeva A.
- Agilinko J.
- Agnes A.
- Agostini C.
- Agoston P.
- Agrawal A.
- Agresta F.
- Aguado H.
- Aguilar Gonzalez M.
- Aguzzoli L.
- Ahad S.
- Ahmadi N.
- Ahmeidat A.
- Ahn J. H.
- Aiken T.
- Aime A.
- Ajlan A.
- Akalin M.
- Akaydin E.
- Akeel N.
- Akgor U.
- Akhtar M. A.
- Akhter Rahman M. M.
- Akilli H.
- Akin E.
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- Publication venue
- J Clin Oncol
- Publication date
- 01/01/2020
- Field of study
PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks
Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study
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- Aawsaj Y.
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- Publication venue
- 'American Society of Clinical Oncology (ASCO)'
- Publication date
- 01/01/2021
- Field of study
PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks
The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Aali A
- Ab Khan M
- Abbas Q
- Abbasi B
- Abbasi-Kangevari M
- Abbasi-Kangevari Z
- Abbastabar H
- Abd-Elsalam S
- Abdelmasseh M
- Abdelwahab AA
- Abdoli G
- Abdulkader RS
- Abdulkadir HA
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- Abedi A
- Abegaz KH
- Abidi H
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- Abolhassani H
- Absalan A
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- Adnani QES
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- Khan AAK
- Khan EA
- Khan G
- Khan MN
- Khanali J
- Khaneghah AM
- Khatab K
- Khatatbeh MM
- Khatib MN
- Khayamzadeh M
- Khezeli M
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- Kim MS
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- Kisa A
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- Klugar M
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- Kolahi A-A
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- Sofi-Mahmudi A
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- Soodejani MT
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- Sotoudeh H
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- Sur D
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- Ullah I
- Ullah S
- Unnikrishnan B
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- Vaziri S
- Velazquez DZ
- Veroux M
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- Violante FS
- Vladimirov SK
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- Woldemariam M
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- Yeshaw Y
- Yismaw Y
- Yonemoto N
- Younis MZ
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- Zangiabadian M
- Zare F
- Zare I
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- Zhang D
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- Zodpey S
- Zoladl M
- Publication venue
- Publication date
- 20/08/2022
- Field of study
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alam N
- Alam S
- Alam T
- Alanezi FM
- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
- Alhabib KF
- Alhassan RK
- Ali M
- Ali S
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Alvis-Zakzuk NJ
- Amare AT
- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
- Amiri F
- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
- Anderlini D
- Anderson JA
- Andrei CL
- Andrei T
- Androudi S
- Angus C
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- Ansari F
- Ansari I
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- Antonazzo IC
- Antonio CAT
- Antony CM
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- Avokpaho EFGA
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- Aynalem YA
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- Banik PC
- Bannick MS
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- Barnighausen TW
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- Bhageerathy R
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- Bijani A
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- Bilano V
- Bin Sayeed MS
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- Biondi A
- Birihane BM
- Bisanzio D
- Bisignano C
- Biswas RK
- Bitew H
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- Bockarie MJ
- Bohlouli S
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- Boloor A
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- Borges G
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- Breitborde NJK
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- Brenner H
- Breusov AV
- Briant PS
- Briggs AM
- Briko AN
- Briko NI
- Britton GB
- Brugha T
- Bryazka D
- Buchbinder R
- Bumgarner BR
- Burkart K
- Burnett RT
- Busse R
- Butt ZA
- Caetano dos Santos FL
- Cahill LE
- Cahuana-Hurtado L
- Cai T
- Callender CSKH
- Camera LA
- Campos-Nonato IR
- Cao J
- Car J
- Car LT
- Cardenas R
- Carreras G
- Carrero JJ
- Carvalho F
- Castaldelli-Maia JM
- Castaneda-Orjuela CA
- Castelpietra G
- Castle CD
- Castro E
- Castro F
- Catala-Lopez F
- Causey K
- Cederroth CR
- Cercy KM
- Cerin E
- Chalek J
- Chandan JS
- Chang AR
- Chang AY
- Chang J-C
- Chang K-L
- Charan J
- Charlson FJ
- Chattu VK
- Chaturvedi S
- Cherbuin N
- Chimed-Ochir O
- Chin KL
- Chirinos-Caceres JL
- Cho DY
- Choi J-YJ
- Christensen H
- Chu D-T
- Chung MT
- Chung S-C
- Cicuttini FM
- Ciobanu LG
- Cirillo M
- Cislaghi B
- Classen TKD
- Cohen AJ
- Collins EL
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- Compton K
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- Cortesi PA
- Costa VM
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- Cowden RG
- Cowie BC
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- Cross DH
- Cross M
- Crowe CS
- Cruz JA
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- Cunningham M
- D'Amico E
- da Silva DD
- Dahlawi SMA
- Dai H
- Dai H
- Damasceno AAM
- Damiani G
- Dandona L
- Dandona R
- Daneshpajouhnejad P
- Dangel WJ
- Danielsson A-K
- Dargan PI
- Darshan BB
- Darwesh AM
- Daryani A
- Das Gupta R
- Das Neves J
- Das JK
- Dash AP
- Davey G
- Davila-Cervantes CA
- Davis AC
- Davitoiu DV
- Davletov K
- De Leo D
- De Neve J-W
- Dean FE
- DeCleene NK
- Deen A
- Defo BK
- Degenhardt L
- DeLang M
- Dellavalle RP
- Demeke FM
- Demoz GT
- Demsie DG
- Denova-Gutierrez E
- Dereje ND
- Deribe K
- Dervenis N
- Desai R
- Desalew A
- Dessie GA
- Deuba K
- Dharmaratne SD
- Dhungana GP
- Dianatinasab M
- Diaz D
- Dichgans M
- Didarloo A
- Dingels ZV
- Dippenaar IN
- Dirac MA
- Djalalinia S
- Do HT
- Dokova K
- Doku DT
- Dolecek C
- Dolgert AJ
- Dorostkar F
- Doshi CP
- Doshi PP
- Doshmangir L
- Douiri A
- Doxey MC
- Doyle KE
- Driscoll TR
- Dubljanin E
- Dunachie SJ
- Duncan BB
- Duraes AR
- Eagan AW
- Ebrahimi H
- Edvardsson D
- Effiong A
- Ehrlich JR
- El Nahas N
- El Sayed I
- El Tantawi M
- El-Jaafary SI
- Elbarazi I
- Elgendy IY
- Elhabashy HR
- Elsharkawy A
- Elyazar IRF
- Emamian MH
- Emmons-Bell S
- Erskine HE
- Eshrati B
- Eskandari K
- Eskandarieh S
- Esmaeilnejad S
- Esmaeilzadeh F
- Esteghamati A
- Esteghamati S
- Estep K
- Etemadi A
- Etisso AE
- Ezekannagha O
- Fanzo J
- Farag T
- Farahmand M
- Faraj A
- Faraon EJA
- Fareed M
- Faridnia R
- Farinha CSES
- Farioli A
- Faris PS
- Faro A
- Faruque M
- Farzadfar F
- Fattahi N
- Fazaeli AA
- Fazlzadeh M
- Feigin VL
- Feldman R
- Fereshtehnejad S-M
- Fernandes E
- Ferrara G
- Ferrara P
- Ferrari AJ
- Ferreira ML
- Feyissa GT
- Filip I
- Fischer F
- Fisher JL
- Fitzgerald R
- Flohr C
- Flor LS
- Foigt NA
- Folayan MO
- Fomenkov AA
- Force LM
- Fornari C
- Forooshani ZSD
- Foroutan M
- Fox JT
- Francis JM
- Frank TD
- Franklin RC
- Freitas M
- Fu W
- Fukumoto T
- Fukutaki K
- Fuller JE
- Fullman N
- Furtado JM
- Gad MM
- Gaidhane AM
- Gakidou E
- Galles NC
- Gallus S
- Gamkrelidze A
- Garcia-Basteiro AL
- Gardner WM
- Geberemariyam BS
- Gebrehiwot AM
- Gebremedhin KB
- Gebremeskel GG
- Gebremeskel LG
- Gebresillassie BM
- Gebreslassie AAAA
- Gela JD
- Geramo YCD
- Geremew A
- Gesesew HA
- Gething PW
- Gezae KE
- Ghadimi M
- Ghadiri K
- Ghaffarifar F
- Ghafourifard M
- Ghajar A
- Ghamari F
- Ghashghaee A
- Ghiasvand H
- Ghith N
- Gholamian A
- Ghosh R
- Giampaoli S
- Gilani SA
- Gill PS
- Gill TK
- Gillum RF
- Ginawi IA
- Ginindza TG
- Gitimoghaddam M
- Giussani G
- Glagn M
- Glushkova EV
- Gnedovskaya EV
- Godinho MA
- Goharinezhad S
- Golechha M
- Goli S
- Gomez RS
- Gona PN
- Gopalani SV
- Goren E
- Gorini G
- Gorman TM
- Gottlich HC
- Goudarzi H
- Goudarzian AH
- Goulart AC
- Goulart BNG
- Grada A
- Greaves F
- Grivna M
- Grosso G
- Gubari MIM
- Gudi N
- Gugnani HC
- Guimaraes ALS
- Guimaraes RA
- Guled RA
- Gultie T
- Guo G
- Guo Y
- Gupta R
- Gupta R
- Gupta T
- Haagsma JA
- Hachinski V
- Haddock B
- Hafezi-Nejad N
- Hafiz A
- Hagins H
- Haile LM
- Haile TG
- Haj-Mirzaian A
- Haj-Mirzaian A
- Hall BJ
- Halvaei I
- Hamadeh RR
- Hameed S
- Hamidi S
- Hamilton EB
- Hammer MS
- Han C
- Han H
- Handiso DW
- Hanif A
- Hankey GJ
- Hanson SW
- Haririan H
- Haro JM
- Harvey JD
- Hasaballah AI
- Hasan MM
- Hasanpoor E
- Hasanzadeh A
- Hashemian M
- Hashi A
- Hassan A
- Hassan S
- Hassanipour S
- Hassankhani H
- Havmoeller RJ
- Hawariat FGW
- Hay RJ
- Hay SI
- Hayat K
- Hayoon AG
- Heibati B
- Heidari B
- Heidari G
- Heidari-Soureshjani R
- Hendrie D
- Henny K
- Henok A
- Henrikson HJ
- Henry NJ
- Herbert ME
- Herrera AMM
- Herteliu C
- Heydarpour F
- Hird TR
- Ho HC
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- Umeokonkwo CD
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- Venketasubramanian N
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- Wickramasinghe ND
- Wiens KE
- Wijeratne T
- Wilner LB
- Wilson S
- Wiysonge CS
- Wojtyniak B
- Woldu G
- Wolfe CDA
- Wondmeneh TG
- Wondmieneh AB
- Wool EE
- Wozniak SS
- Wu A-M
- Wu C
- Wu J
- Wunrow HY
- Xie Y
- Xu G
- Xu R
- Yadgir S
- Yamada T
- Yamagishi K
- Yaminfirooz M
- Yano Y
- Yaya S
- Yazdi-Feyzabadi V
- Yearwood JA
- Yeheyis TY
- Yeshitila YG
- Yilgwan CS
- Yilma MT
- Yip P
- Yonemoto N
- Yoon S-J
- York HW
- Younis MZ
- Younker TP
- Yousefi B
- Yousefi Z
- Yousefifard M
- Yousefinezhadi T
- Yousuf AY
- Yu C
- Yu Y
- Yuan C-W
- Yuce D
- Yusefzadeh H
- Zadey S
- Zahabi SS
- Zaidi SS
- Zaki L
- Zaki MES
- Zakzuk J
- Zamani M
- Zamanian M
- Zandian H
- Zangeneh A
- Zarafshan H
- Zastrozhin MS
- Zewdie KA
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhao JT
- Zhao X-JG
- Zhao Y
- Zheleva B
- Zheng P
- Zhou M
- Zhu C
- Ziapour A
- Zimsen SRM
- Zlavog BS
- Zodpey S
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/10/2020
- Field of study
Five insights from the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alam N
- Alam S
- Alam T
- Alanezi FM
- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
- Alhabib KF
- Alhassan RK
- Ali M
- Ali S
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Alvis-Zakzuk NJ
- Amare AT
- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
- Amiri F
- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
- Anderlini D
- Anderson JA
- Andrei CL
- Andrei T
- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonazzo IC
- Antonio CAT
- Antony CM
- Antriyandarti E
- Anvari D
- Anwer R
- Appiah SCY
- Arab-Zozani M
- Arabloo J
- Aravkin AY
- Arba AAK
- Aremu O
- Ariani F
- Aripov T
- Armoon B
- Arnlov J
- Arowosegbe OO
- Aryal KK
- Arzani A
- Asaad M
- Asadi-Aliabadi M
- Asadi-Pooya AA
- Asgari S
- Asghari B
- Ashbaugh C
- Assmus M
- Atafar Z
- Athari SS
- Atnafu DD
- Atout MMW
- Atre SR
- Atteraya MS
- Ausloos F
- Ausloos M
- Avila-Burgos L
- Avokpaho EFGA
- Ayano G
- Ayanore MA
- Aynalem GL
- Aynalem YA
- Ayza MA
- Azari S
- Azarian G
- Azene ZN
- Azhar G
- Azzopardi PS
- Babaee E
- Badawi A
- Badiye AD
- Bagherzadeh M
- Bagli E
- Bahrami MA
- Baig AA
- Bairwa M
- Bakhshaei MH
- Bakhtiari A
- Bakkannavar SM
- Balachandran A
- Balakrishnan S
- Balalla S
- Balassyano S
- Baldasseroni A
- Bali AO
- Ball K
- Ballew SH
- Balzi D
- Banach M
- Bandpei MAM
- Banerjee SK
- Banik PC
- Bannick MS
- Bante AB
- Bante SA
- Baraki AG
- Barboza MA
- Barker-Collo SL
- Barnighausen TW
- Barrero LH
- Barthelemy CM
- Barua L
- Barzegar A
- Basaleem H
- Bassat Q
- Basu S
- Baune BT
- Bayati M
- Baye BA
- Bazmandegan G
- Becker JS
- Bedi N
- Beghi E
- Behzadifar M
- Bejot Y
- Bekuma TTT
- Bell ML
- Bello AK
- Ben L
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- Publication venue
- Publication date
- 01/01/2020
- Field of study
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Peer reviewe
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019 : a comprehensive demographic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati Cristiana
- Abbas Kaja M.
- Abbasi Mohammad
- Abbasi-Kangevari Mohsen
- Abbasifard Mitra
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdelalim Ahmed
- Abdollahi Mohammad
- Abdollahpour Ibrahim
- Abedi Aidin
- Abedi Parisa
- Abegaz Kedir H.
- Abolhassani Hassan
- Abosetugn Akine E.
- Aboyans Victor
- Abrams Elissa M.
- Abreu Lucas G.
- Abrigo Michael R. M.
- Abu Haimed Abdulaziz K.
- Abu-Gharbieh Eman
- Abu-Raddad Laith J.
- Abualhasan Ahmed
- Abushouk Abdelrahman I.
- Acebedo Alyssa
- Ackerman Ilana N.
- Adabi Maryam
- Adair Tim
- Adamu Abdu A.
- Adebayo Oladimeji M.
- Adedeji Isaac A.
- Adekanmbi Victor
- Adelson Jaimie D.
- Adeoye Abiodun M.
- Adetokunboh Olatunji O.
- Adham Davoud
- Advani Shailesh M.
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- Afshari Mahdi
- Afshin Ashkan
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- Aghaali Mohammad
- Aghamir Seyed M.
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- Ahmadi Alireza
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- Nnaji Chukwudi A.
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- Nsoesie Elaine
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- Pourjafar Hadi
- Pourmalek Farshad
- Pourmirza Kalhori Reza
- Pourshams Akram
- Poznanska Anna
- Prada Sergio I.
- Prakash Sanjay
- Prakash V.
- Prasad Narayan
- Preotescu Liliana
- Pribadi Dimas R.
- Pupillo Elisabetta
- Quazi Syed Zahiruddin
- Rabiee Mohammad
- Rabiee Navid
- Radfar Amir
- Rafiee Ata
- Rafiei Alireza
- Raggi Alberto
- Rahim Fakher
- Rahimi-Movaghar Afarin
- Rahman Mohammad H.
- Rahman Muhammad A.
- Rajabpour-Sanati Ali
- Rajati Fatemeh
- Rakovac Ivo
- Ram Pradhum
- Ramezanzadeh Kiana
- Rana Saleem M.
- Ranabhat Chhabi L.
- Ranta Annemarei
- Rao Puja C.
- Rao Sowmya J.
- Rasella Davide
- Rashedi Vahid
- Rastogi Prateek
- Rath Goura K.
- Rathi Priya
- Rawaf David L.
- Rawaf Salman
- Rawal Lal
- Rawassizadeh Reza
- Rawat Ramu
- Razo Christian
- Redford Sofia B.
- Regassa Lemma D.
- Reiner Robert C.
- Reinig Nickolas
- Reitsma Marissa B.
- Remuzzi Giuseppe
- Renjith Vishnu
- Renzaho Andre M. N. (R17978)
- Ärnlöv Johan
- Øverland Simon
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019.
Methods: 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10–14 and 50–54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. Uncertainty was propagated throughout the demographic estimation process, including fertility, mortality, and population, with 1000 draw-level estimates produced for each metric. Findings: The global TFR decreased from 2·72 (95% uncertainty interval [UI] 2·66–2·79) in 2000 to 2·31 (2·17–2·46) in 2019. Global annual livebirths increased from 134·5 million (131·5–137·8) in 2000 to a peak of 139·6 million (133·0–146·9) in 2016. Global livebirths then declined to 135·3 million (127·2–144·1) in 2019. Of the 204 countries and territories included in this study, in 2019, 102 had a TFR lower than 2·1, which is considered a good approximation of replacement-level fertility. All countries in sub-Saharan Africa had TFRs above replacement level in 2019 and accounted for 27·1% (95% UI 26·4–27·8) of global livebirths. Global life expectancy at birth increased from 67·2 years (95% UI 66·8–67·6) in 2000 to 73·5 years (72·8–74·3) in 2019. The total number of deaths increased from 50·7 million (49·5–51·9) in 2000 to 56·5 million (53·7–59·2) in 2019. Under-5 deaths declined from 9·6 million (9·1–10·3) in 2000 to 5·0 million (4·3–6·0) in 2019. Global population increased by 25·7%, from 6·2 billion (6·0–6·3) in 2000 to 7·7 billion (7·5–8·0) in 2019. In 2019, 34 countries had negative natural rates of increase; in 17 of these, the population declined because immigration was not sufficient to counteract the negative rate of decline. Globally, HALE increased from 58·6 years (56·1–60·8) in 2000 to 63·5 years (60·8–66·1) in 2019. HALE increased in 202 of 204 countries and territories between 2000 and 2019
The global, regional, and national burden of adult lip, oral, and pharyngeal cancer in 204 countries and territories:A systematic analysis for the Global Burden of Disease Study 2019
- Author
- Ababneh Emad
- Abd-Elsalam Sherief
- Abdoun Meriem
- Abidi Hassan
- Abu-Gharbieh Eman
- Abubaker Ali Hiwa
- Acheson Alistair R.
- Adane Tigist Demssew
- Addo Isaac Yeboah
- Ahmad Aqeel
- Ahmad Sajjad
- Ahmed Rashid Tarik
- Akonde Maxwell
- Al Hamad Hanadi
- Al-Maweri Sadeq Ali
- Alahdab Fares
- Alam Tahiya
- Alimohamadi Yousef
- Alipour Vahid
- Alsharif Ubai
- Ansari-Moghaddam Alireza
- Antunes Jose Leopoldo Ferreira
- Anwar Sumadi Lukman
- Anyasodor Anayochukwu Edward
- Arabloo Jalal
- Aravkin Aleksandr Y.
- Aruleba Raphael Taiwo
- Asaad Malke
- Ashraf Tahira
- Athari Seyyed Shamsadin
- Attia Sameh
- Azadnajafabad Sina
- Azangou-Khyavy Mohammadreza
- Badar Muhammad
- Baghcheghi Nayereh
- Banach Maciej
- Bardhan Mainak
- Barqawi Hiba Jawdat
- Bashir Nasir Z.
- Bashiri Azadeh
- Benzian Habib
- Bernabe Eduardo
- Bhagat Devidas S.
- Bhojaraja Vijayalakshmi S.
- Bjørge Tone
- Bouaoud Souad
- Braithwaite Dejana
- Briko Nikolay Ivanovich
- Calina Daniela
- Carreras Giulia
- Chakraborty Promit Ananyo
- Chandan S.N.
- Chattu Vijay Kumar
- Chaurasia Akhilanand
- Chen Meng Xuan
- Cho William C. S.
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Chung Eunice
- Compton Kelly
- Cruz-Martins Natália
- Da Cunha Amanda Ramos
- Dadras Omid
- Dai Xiaochen
- Dandona Lalit
- Dandona Rakhi
- Daneshpajouhnejad Parnaz
- Darvishi Cheshmeh Soltani Reza
- Darwesh Aso Mohammad
- Dean Frances E.
- Debela Sisay Abebe
- Derbew Molla Meseret
- Dessalegn Fikadu Nugusu
- Dianati-Nasab Mostafa
- Digesa Lankamo Ena
- Dixit Abhinav
- Dixit Shilpi Gupta
- Djalalinia Shirin
- Drangsholt Mark Thomas
- El Sayed Iman
- El Tantawi Maha
- Enyew Daniel Berhanie
- Erku Daniel Asfaw
- Ezzeddini Rana
- Fagbamigbe Adeniyi Francis
- Falzone Luca
- Fetensa Getahun
- Force Lisa M.
- Fu Weijia
- Fukumoto Takeshi
- Gaewkhiew Piyada
- Gallus Silvano
- Gebrehiwot Mesfin
- Ghashghaee Ahmad
- Gill Paramjit Singh
- Golechha Mahaveer
- Goleij Pouya
- Gomez Ricardo Santiago
- Gorini Giuseppe
- Guimaraes
- Gupta Bhawna
- Gupta Sapna
- Gupta Veer Bala
- Gupta Vivek Kumar
- Haj-Mirzaian Arvin
- Halboub Esam S.
- Halwani Rabih
- Hanif Asif
- Hariyani Ninuk
- Harorani Mehdi
- Hasani Hamidreza
- Hassan Abbas M.
- Hassanipour Soheil
- Hassen Mohammed Bheser
- Hay Simon I.
- Hayat Khezar
- Henrikson Hannah Jacqueline
- Herrera-Serna Brenda Yuliana
- Holla Ramesh
- Horita Nobuyuki
- Hosseinzadeh Mehdi
- Hugo Fernando N.
- Hussain Salman
- Ilesanmi Olayinka Stephen
- Ilic Irena M.
- Ilic Milena D.
- Isola Gaetano
- Jaiswal Abhishek
- Jani Chinmay T.
- Javaheri Tahereh
- Jayarajah Umesh
- Jayaram Shubha
- Joseph Nitin
- Kadashetti Vidya
- Kandaswamy Eswar
- Karanth Shama D.
- Karaye Ibraheem M.
- Kauppila Joonas H.
- Kaur Harkiran
- Kerr Alexander R.
- Keykhaei Mohammad
- Khader Yousef Saleh
- Khajuria Himanshu
- Khanali Javad
- Khatib Mahalaqua Nazli
- Khayat Kashani Hamid Reza
- Khazeei Tabari Mohammad Amin
- Kim Min Seo
- Kocarnik Jonathan M.
- Kompani Farzad
- Koohestani Hamid Reza
- Kumar G. Anil
- Kurmi Om P.
- La Vecchia Carlo
- Lal Dharmesh Kumar
- Landires Iván
- Lasrado Savita
- Ledda Caterina
- Lee Yo Han
- Libra Massimo
- Lim Stephen S.
- Listl Stefan
- Lopukhov Platon D.
- Lu Dan
- Mafi Ahmad R.
- Mahumud Rashidul Alam
- Malik Ahmad Azam
- Manjula S.
- Mathur Manu Raj
- Maulud Sazan Qadir
- Meena Jitendra Kumar
- Mehrabi Nasab Entezar
- Mestrovic Tomislav
- Mirfakhraie Reza
- Misganaw Awoke
- Mishra Rashmi
- Misra Sanjeev
- Mithra Prasanna
- Mohammad Yousef
- Mohammadi Esmaeil
- Mohammadi Mokhtar
- Mokdad Ali H.
- Moni Mohammad Ali
- Moraga Paula
- Morrison Shane Douglas
- Mozaffari Hamid Reza
- Mubarik Sumaira
- Murray Christopher J. L.
- Nair Tapas Sadasivan
- Narasimha Swamy Sreenivas
- Narayana Aparna Ichalangod
- Nassereldine Hasan
- Natto Zuhair S.
- Nayak Biswa Prakash
- Negru Serban Mircea
- Nggada Haruna Asura
- Nouraei Hasti
- Nuñez-Samudio Virginia
- Oancea Bogdan
- Olagunju
- Omar Bali Ahmed
- Padron-Monedero Alicia
- Padubidri Jagadish Rao
- Pandey Anamika
- Pardhan Shahina
- Patel Jay
- Pennini Alyssa
- Pezzani Raffaele
- Piracha Zahra Zahid
- Rabiee Navid
- Radhakrishnan Raghu Anekal
- Radhakrishnan Venkatraman
- Rahmani Amir Masoud
- Rahmanian Vahid
- Rao Chythra R.
- Rao Sowmya J.
- Rath Goura Kishor
- Rawaf David Laith
- Rawaf Salman
- Rawassizadeh Reza
- Razeghinia Mohammad Sadegh
- re Luiz Sena
- rew T.
- Rezaei Nazila
- Rezaei Negar
- Rezaei Nima
- Rezapour Aziz
- Riad Abanoub
- Roberts Thomas J.
- Romero-RRodríguez Esperanza
- Roshandel Gholamreza
- Saddik Basema
- Saeb Mohammad Reza
- Saeed Umar
- Safaei Mohsen
- Sahebazzamani Maryam
- Sahebkar Amirhossein
- Salek Farrokhi Amir
- Samy Abdallah M.
- Santric-Milicevic Milena M.
- Sathian Brijesh
- Satpathy Maheswar
- Senthilkumaran Subramanian
- Seylani Allen
- Shafaat Omid
- Shahsavari Hamid R.
- Shamsoddin Erfan
- Sharew Mequannent Melaku
- Sharifi-Rad Javad
- Shetty Jeevan K.
- Shivakumar K.M.
- Shobeiri Parnian
- Shorofi Seyed Afshin
- Shrestha Sunil
- Siddappa Malleshappa Sudeep K.
- Singh Garima
- Singh Jasvinder A.
- Singh Paramdeep
- Sinha Dhirendra Narain
- Solomon Yonatan
- Suleman Muhammad
- Suliankatchi Abdulkader Rizwan
- Taheri Abkenar Yasaman
- Talaat Iman M.
- Tan Ker-Kan
- Tbakhi Abdelghani
- Thiyagarajan Arulmani
- Tiyuri Amir
- Tovani-Palone Marcos Roberto
- Unnikrishnan Bhaskaran
- Vo Bay
- Volovat Simona Ruxandra
- Wallace Lindsey E.
- Wang Cong
- Westerman Ronny
- Wickramasinghe Nuwan Darshana
- Xiao Hong
- Xu Rixing
- Yu Chuanhua
- Yuce Deniz
- Yunusa Ismaeel
- Zadnik Vesna
- Zare Iman
- Zhang Zhi-Jiang
- Zoladl Mohammad
- Šekerija Mario
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Importance Lip, oral, and pharyngeal cancers are important contributors to cancer burden worldwide, and a comprehensive evaluation of their burden globally, regionally, and nationally is crucial for effective policy planning.Objective To analyze the total and risk-attributable burden of lip and oral cavity cancer (LOC) and other pharyngeal cancer (OPC) for 204 countries and territories and by Socio-demographic Index (SDI) using 2019 Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study estimates.Evidence Review The incidence, mortality, and disability-adjusted life years (DALYs) due to LOC and OPC from 1990 to 2019 were estimated using GBD 2019 methods. The GBD 2019 comparative risk assessment framework was used to estimate the proportion of deaths and DALYs for LOC and OPC attributable to smoking, tobacco, and alcohol consumption in 2019.Findings In 2019, 370 000 (95% uncertainty interval [UI], 338 000-401 000) cases and 199 000 (95% UI, 181 000-217 000) deaths for LOC and 167 000 (95% UI, 153 000-180 000) cases and 114 000 (95% UI, 103 000-126 000) deaths for OPC were estimated to occur globally, contributing 5.5 million (95% UI, 5.0-6.0 million) and 3.2 million (95% UI, 2.9-3.6 million) DALYs, respectively. From 1990 to 2019, low-middle and low SDI regions consistently showed the highest age-standardized mortality rates due to LOC and OPC, while the high SDI strata exhibited age-standardized incidence rates decreasing for LOC and increasing for OPC. Globally in 2019, smoking had the greatest contribution to risk-attributable OPC deaths for both sexes (55.8% [95% UI, 49.2%-62.0%] of all OPC deaths in male individuals and 17.4% [95% UI, 13.8%-21.2%] of all OPC deaths in female individuals). Smoking and alcohol both contributed to substantial LOC deaths globally among male individuals (42.3% [95% UI, 35.2%-48.6%] and 40.2% [95% UI, 33.3%-46.8%] of all risk-attributable cancer deaths, respectively), while chewing tobacco contributed to the greatest attributable LOC deaths among female individuals (27.6% [95% UI, 21.5%-33.8%]), driven by high risk-attributable burden in South and Southeast Asia.Conclusions and Relevance In this systematic analysis, disparities in LOC and OPC burden existed across the SDI spectrum, and a considerable percentage of burden was attributable to tobacco and alcohol use. These estimates can contribute to an understanding of the distribution and disparities in LOC and OPC burden globally and support cancer control planning efforts
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