15 research outputs found
Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy.
- Author
- Anum Diana
- Attie Alan D
- Cao Yang
- Carroll Luke
- Chella Krishnan Karthickeyan
- Churchill Gary
- El Hachem Elie-Julien
- Gerdes Gyuricza Isabela
- James David E
- Kaczor-Urbanowicz Karolina Elżbieta
- Keller Mark P
- Lee Chi Fung
- Light Christine
- Lusis Aldons J
- Pan Calvin
- Parker Benjamin
- Patel Sanjeet G
- Pellegrini Matteo
- Rosenthal Nadia
- Seldin Marcus M
- Shravah Varun
- Vegas Alexis Diaz
- Publication venue
- The Mouseion at the JAXlibrary
- Publication date
- 01/06/2023
- Field of study
Mitochondria play an important role in both normal heart function and disease etiology. We report analysis of common genetic variations contributing to mitochondrial and heart functions using an integrative proteomics approach in a panel of inbred mouse strains called the Hybrid Mouse Diversity Panel (HMDP). We performed a whole heart proteome study in the HMDP (72 strains, n=2-3 mice) and retrieved 848 mitochondrial proteins (quantified in ≥50 strains). High- resolution association mapping on their relative abundance levels revealed three trans-acting genetic loci on chromosomes (chr) 7, 13 and 17 that regulate distinct classes of mitochondrial proteins as well as cardiac hypertrophy. DAVID enrichment analyses of genes regulated by each of the loci revealed that the chr13 locus was highly enriched for complex-I proteins (24 proteins, P=2.2E-61), the chr17 locus for mitochondrial ribonucleoprotein complex (17 proteins, P=3.1E-25) and the chr7 locus for ubiquinone biosynthesis (3 proteins, P=6.9E-05). Follow-up high resolution regional mapping identified NDUFS4, LRPPRC and COQ7 as the candidate genes for chr13, chr17 and chr7 loci, respectively, and both experimental and statistical analyses supported their causal roles. Furthermore, a large cohort of Diversity Outbred mice was used to corroborate Lrpprc gene as a driver of mitochondrial DNA (mtDNA)-encoded gene regulation, and to show that the chr17 locus is specific to heart. Variations in all three loci were associated with heart mass in at least one of two independent heart stress models, namely, isoproterenol-induced heart failure and diet-induced obesity. These findings suggest that common variations in certain mitochondrial proteins can act in trans to influence tissue-specific mitochondrial functions and contribute to heart hypertrophy, eluci- dating mechanisms that may underlie genetic susceptibility to heart failure in human populations
A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.
- Author
- Aberson Christopher
- Aczel Balazs
- Adamkovic Matus
- Adamus Sylwia
- Adetula Adeyemi
- Adetula Gabriel Agboola
- Adiguzel Arca
- Adoric Vera Cubela
- Afhami Reza
- Agadullina Elena
- Agesin Bamikole Bamikole
- Ahlgren Lina
- Ahmed Afroja
- Ahn El Rim
- Akgoz Aysegul
- Akkas Handan
- Alaei Ravin
- Albayrak-Aydemir Nihan
- Allred Tara Bulut
- Almeida Inês
- Alper Sinan
- Alvarez Daniela Serrato
- Alves Sara
- Andreychik Michael
- Anjum Gulnaz
- Ankushev Vladislav
- Anne Michele
- Antazo Benedict
- Antfolk Jan
- Anton-Boicuk Lisa
- Antoniadi Maria
- Anvari Farid
- Arinze Azuka Ikechukwu
- Arinze Nwadiogo
- Arinze Nwadiogo Chisom
- Ariyabuddhiphongs Kris
- Armstrong Marie
- Arnal Jack
- Arriaga Patrícia
- Artner Richard
- Aruta John Jamir Benzon
- Arvanitis Alexios
- Ashworth Logan
- Ask Karl
- Askelund Adrian Dahl
- Atari Mohammad
- Azab Habiba
- Azevedo Flavio
- Azouaghe Soufian
- Babincak Peter
- Badidi Touhami
- Bai Hui
- Baklanova Ekaterina
- Balas Benjamin
- Balci Busra Bahar
- Ballada Christine Joy
- Ballantyne Tonia
- Balt Nina
- Baník Gabriel
- Barba-Sánchez Alan
- Barbosa Sergio
- Barzykowski Krystian
- Basabe Nekane
- Baskin Ernest
- Basnight-Brown Dana
- Batres Carlota
- Bavolar Jozef
- Beaudry Jennifer
- Becker Maja
- Behzadnia Behzad
- Beitner Julia
- Belaus Anabel
- Belhaj Abdelkarim
- Bennett-Day Brooke
- Berkessel Jana
- Bernardo Márcia
- Beshears Julie
- Betlehem Ruben
- Bhushan Braj
- Bialek Michal
- Bialobrzeska Olga
- Białek Michał
- Bijlstra Gijsbert
- Blake Khandis
- Blaut Agata
- Bloxsom Nicholas
- Bobowik Magdalena
- Bogatyreva Natalia
- Bokkour Ahmed
- Bonick Judson
- Borras-Guevara Martha Lucia
- Bosch Jasmijn
- Bosma Minke Jasmijn
- Boucher Leanne
- Boudesseul Jordane
- Bozdoc Andreea Ioana
- Bradford Maria
- Bran Alexandre
- Brandt Mark
- Bravo Olalla Niño
- Brohmer Hilmar
- Buchanan Erin
- Bundt Carsten
- Burak Elif Gizem Demirag
- Burin Debora
- Butt Muhammad Mussaffa
- Bylinina Lisa
- Caballero Amparo
- Cai Sun Jun
- Calin-Jageman Robert
- Calvillo Dustin
- Campos Olatz
- Capizzi Mariagrazia
- Carpentier Joelle
- Carrera Pilar
- Carvalho Lilian
- Ceary Chris
- Cellini Nicola
- Chandel Priyanka
- Chartier Christopher
- Charyate Abdelilah
- Chatard Armand
- Chen Sau-Chin
- Chen Zhang
- Chevallier Coralie
- Chittham Phakkanun
- Chiu Faith
- Choi Eunsoo
- Chopik William
- Chou Weilun
- Christopherson Cody
- Chuan-Peng Hu
- Coelho Gabriel Lins de Holanda
- Coetzee Vinet
- Cohen Noga
- Coles Nicholas
- Collins W. Matthew
- Colloff Melissa
- Cook Corey
- Corral-Frías Nadia
- Correa Pablo Sebastián
- Correia Rita
- Crawford Matthew
- Cruz Vásquez Julio
- Cubillas Carmelo
- Cyrus-Lai Wilson
- Czamanski-Cohen Johanna
- Czarnek Gabriela
- Cárcamo Rodrigo
- Daches Shimrit
- Dalgar Ilker
- Damnjanović Kaja
- Daniels Judith
- Danvers Alexander
- Davis William
- Day Chris
- De La Rosa-Gómez Anabel
- de Lima Tiago Jessé Souza
- de Souza Luana Elayne Cunha
- DeBruine Lisa
- del Carmen Espinoza Maria
- Delgado Lady Grey Javela
- Desai Kermeka
- Dixson Barnaby
- Dixson Barnaby James Wyld
- Djamai Ikhlas
- Djordjevic Jasna Milosevic
- Dodaj Arta
- Domurat Artur
- Dorison Charles
- Doğan Uğur
- Drexler Shira Meir
- Du Hongfei
- Du Xinkai
- Dubrov Dmitrii
- Dujols Olivier
- Dumont Kitty
- Dunham Yarrow
- Dunleavy Daniel
- Dursun Pinar
- Ebersole Charles
- Ebert Tobias
- El Arabi Kanza Ait
- Elouafa Jamal
- Escobar María Josefina
- Espinoza Barría Mauricio
- Esteban-Serna Celia
- Estrada-Mejia Catalina
- Etabari Zahra
- Eudave Luis
- Evans Kortnee
- Evans Thomas
- Eşkisu Mustafa
- FatahModarres Saiedeh
- Fedotov Maksim
- Feinberg David
- Feldman Gilad
- Fernandez Ana Maria
- Ferreira Ana
- Ferreira Diogo
- Ferreira Paulo
- Filip Katarzyna
- Findor Andrej
- Flake Jessica
- Floerke Victoria
- Flowe Heather
- Forbes Paul
- Foroni Francesco
- Forscher Patrick
- Freeman Jonathan
- Friedemann Maja
- Frizzo Thomas
- Frohlich Brooke
- Frías-Armenta Martha
- Galindo-Caballero Oscar
- Garcia Adolfo
- Garcia Elkin Oswaldo Luis
- Gardiner Gwendolyn
- Gawryluk Katarzyna
- Geiger Sandra
- Geniole Shawn
- Gialitaki Zoi
- Gilboa-Schechtman Eva
- Gilead Michael
- Gill Tripat
- Giolla Erik Mac
- Gjoneska Biljana
- Godbersen Hendrik
- Gogan Taylor
- Goldenberg Amit
- Golik Karolina
- González-Santoyo Isaac
- Gordon-Finlayson Alasdair
- Gourdon-Kanhukamwe Amélie
- Grano Caterina
- Gračanin Asmir
- Greenburgh Anna
- Grigoryev Dmitry
- Grinberg Maurice
- Gross James
- Groyecka-Bernard Agata
- Grzech Karolina
- Götz Friedrich
- Gülgöz Sami
- Habib Sumaiya
- Hahn Amanda
- Hajdu Nandor
- Hanel Paul
- Haque Shamsul
- Hareli Shlomo
- Hartanto Andree
- Harutyunyan Mikayel
- Hatami Javad
- Hedgebeth Mattie
- Hehman Eric
- Hofer Gabriela
- Holford Dawn Liu
- Hostler Thomas
- House Thea
- Hoyer Karlijn
- Hricova Monika
- Hristova Evgeniya
- Hruška Matej
- Hsu Rafael
- Hsu Tsuyueh
- Hu Chuan-Peng
- Hubena Barbora
- Ibanez Agustin
- Idzikowska Katarzyna
- Ihaya Keiko
- IJzerman Hans
- Inzlicht Michael
- Irrazabal Natalia
- Isager Peder Mortvedt
- Ishii Tatsunori
- Ishkhanyan Byurakn
- Ito Kenichi
- Ivanov Aleksandr
- Ivory James
- Iyer Aishwarya
- Izquierdo Sara Morales
- Jackson Emily
- Jaeger Bastian
- Janak Allison
- Jang Chaning
- Janjić Kristina
- Janssen Steve
- Jaremka Lisa
- Jarukasemthawee Somboon
- Jaworska Katarzyna
- Jernsäther Teodor
- Jiang Zhongqing
- Jimenez-Leal William
- Johannes Niklas
- Jones Benedict
- Jones Marc
- Jose Paul
- Joy-Gaba Jennifer
- Jurković Anita Penić
- Jzerman Hans
- Kadreva Veselina Hristova
- Kaliska Lada
- Kamburidis Julia
- Kaminski Gwenaël
- Kappes Heather
- Kapucu Aycan
- Karaarslan Cemre
- Karaaslan Aslan
- Karababa Alper
- Karashiali Christiana
- Kardum Igor
- Karekla Maria
- Karsten Julie
- Kassianos Angelos
- Kačmár Pavol
- Khaoudi Ahmed
- Khosla Meetu
- Kielińska Julita
- Kirgizova Komila
- Klein Richard
- Klevjer Kristoffer
- Kocalar Halil Emre
- Kocsel Natália
- Kocsor Ferenc
- Koehn Monica
- Kohlová Markéta Braun
- Kolen Anouk
- Konova Irina
- Koptjevskaja-Tamm Maria
- Korbmacher Max
- Kossowska Małgorzata
- Kovic Vanja
- Kowal Marta
- Kozma Luca
- Kołodziej Sabina
- Krafnick Anthony
- Kraus Sue
- Kremer Inbal
- Križanić Valerija
- Krupić Dajana
- Krupić Dino
- Kruse Elliott
- Kujur Pratibha
- Kung Chun-Chia
- Kung Franki
- Kunisato Yoshihiko
- Kunst Jonas
- Kurfali Merve
- Kurfalı Murathan
- Kushnir Elizaveta
- Kuzminska Anna
- Kácha Ondřej
- Kökönyei Gyöngyi
- Körner Anita
- Lamm Claus
- Landry Anais Thibault
- Law Wilbert
- Lazarevic Ljiljana
- Lee Ai-Suan
- Lee Jeong Min
- Lee Kean Mun
- Legate Nicole
- Lekkou Eleimonitria
- Leongómez Juan David
- Leonis Trinity
- Lerner Jennifer
- Levitan Carmel
- Levy Neil
- Lewis David
- Lewis Neil
- Lewis Savannah
- Li Manyu
- Li Ranran
- Li Yansong
- Lima Tiago
- Lin Hause
- Lin Yijun
- Lindemans Jan
- Lins Samuel
- Liu Qing-Lan
- Liuzza Marco Tullio
- Lu Jackson
- Lucas Marc
- Lutz Johannes
- Macapagal Paulo Manuel
- Maeura Nao
- Majeed Nadyanna
- Maldonado Mónica Alarcón
- Malik Sadia
- Mallik Peter
- Manavalan Mathi
- Manley Harry
- Manunta Efisio
- Marcu Gabriela
- Marcu Gabriela Mariana
- Marinova Evelina
- Markiewicz Łukasz
- Marko Dafne
- Marszalek Magdalena
- Martinez-Zelaya Gonzalo
- Martins Diogo
- Martončik Marcel
- Massoni Sébastien
- Mateo Nino Jose
- Maturan Princess Lovella G.
- Mburu Georgina
- McCarthy Randy
- Mefoh Philip
- Menon Madhavi
- Mensink Michael
- Mentser Sari
- Messerschmidt Johanna
- Metin-Orta Irem
- Michalak Nicholas
- Micheli Leticia
- Miller Jeremy
- Mioni Giovanna
- Miranda Jacob
- Misiak Michal
- Mokady Aviv
- Mola Débora
- Monajem Arash
- Monteiro Renan
- Moon Karis
- Moreau David
- Morey Richard
- Morvinski Coby
- Mosannenzadeh Farnaz
- Moshontz Hannah
- Muchembled Fany
- Mues Chiel
- Muminov Abdumalik
- Musser Erica
- Muñoz-Reyes Jose Antonio
- Nadif Khaoula
- Nakayama Masataka
- Nauman Rafia
- Ndukaihe Izuchukwu
- Nedelcheva-Datsova Mina
- Neyroud Lison
- Ng Wee Qin
- Nielsen Tonje
- Nilsonne Gustav
- Nock Nora
- Noone Chris
- Norton James
- Novak Sarah
- Nussinson Ravit
- Ogbonnaya Chisom Esther
- Oh Dong Won
- Okan Ceylan
- Oldmeadow Julian
- Oliveira Raquel
- Olofsson Jonas
- Olsen Jerome
- Ong Chew Wei
- Oosterlinck Marlies
- Orjiakor Charles
- Ortiz Manuel
- Ortiz María Victoria
- Ostermann Thomas
- Ouherrou Nihal
- Owsley Nicholas
- Ozery Daphna Hausman
- Očovaj Sanja Batić
- O’Mara Kunz Erin
- Pande Babita
- Pantazi Myrto
- Papachristopoulos Konstantinos
- Papadatou-Pastou Marietta
- Parashar Neha
- Parganiha Arti
- Paris Bastien
- Paruzel-Czachura Mariola
- Parveen Noorshama
- Parzuchowski Michal
- Pati Atanu Kumar
- Pavlacic Jeffrey
- Peltola Henna-Riikka
- Perillo Jennifer
- Peters Kim
- Pfuhl Gerit
- Philipp Michael
- Pich Olivia
- Pilecka Natalia
- Pineda Lina Maria Sanabria
- Pinto Isabel
- Pit Ilse
- Pizarro José
- Polo Pablo
- Pourafshari Razieh
- Pradhan Sraddha
- Primbs Maximilian
- Pronizius Ekaterina
- Protzko John
- Prusova Irina
- Przybylski Andrew
- Putz Ádám
- Páez Darío
- Pálfi Bence
- Pérez Laura Calderón
- Pöntinen Sara
- Qi Yue
- Quirin Markus
- Rachev Nikolay
- Radtke Theda
- Rahal Rima-Maria
- Rana Kafeel
- Razza Timothy
- Reeck Crystal
- Reggev Niv
- Reips Ulf-Dietrich
- Ren Dongning
- Rentfrow Peter
- Reyna Cecilia
- Ribeiro Gianni
- Ribeiro Matheus Fernando Felix
- Ribeiro Rafael
- Ricaurte Danilo Zambrano
- Richard Karley
- Ritchie Kay
- Ritchie Stuart
- Roczniewska Marta
- Rojas-Berscia Luis Miguel
- Romanova Marina
- Ropovik Ivan
- Rosa Anna Dalla
- Ross Robert
- Ruiz-Dodobara Fernando
- Ruiz-Fernández Susana
- Rule Nicholas
- Röer Jan Philipp
- Sacakli Asli
- Samojlenko Lara
- Sampaio Waldir
- Santos Anabela Caetano
- Santos Diana
- Sarda Elisa
- Saribay S. Adil
- Sarieva Irena
- Sarıoğuz Eylül
- Sato Wataru
- Saunders Blair
- Sawicki Przemysław
- Say Nicolas
- Schei Vidar
- Schild Christoph
- Schmid Irina
- Schmidt Kathleen
- Schmidt Nadya-Daniela
- Schorch Sebastian
- Schrover Elke
- Schrötter Jana
- Schubert Thomas
- Schwerdtfeger Andreas
- Schönefeld Victoria
- Schütz Astrid
- Searston Rachel
- Seehuus Martin
- Sesar Kristina
- Shani Yaniv
- Shankland Rebecca
- Sharifian MohammadHasan
- Sharman Leah
- Shiramazu Victor
- Sikka Pilleriin
- Silan Miguel
- Silva Jaime
- Simchon Almog
- Simonovic Nicolle
- Singer Gage
- Singh Margaret
- Sinkolova Sladjana
- Sirota Miroslav
- Sleegers Willem
- Sloane Guyan
- Solas Sara Álvarez
- Solorzano Claudio Singh
- Song Xin
- Sorokowska Agnieszka
- Sorokowski Piotr
- Soto Jose
- Sousa Daniela
- Sparacio Alessandro
- Stadel Marie
- Stanke Franziska
- Steffens Niklas
- Stephen Ian
- Stern Julia
- Sternglanz R. Weylin
- Stevens Laura
- Stewart Suzanne L.K.
- Stieger Stefan
- Stojanovska Dragana
- Stojanovska Marija
- Stolier Ryan
- Storage Daniel
- Stoyanova Alina
- Studzinska Anna
- Su-May Terri Tan
- Suavansri Panita
- Suchow Jordan
- Sullivan Gavin Brent
- Sunami Naoyuki
- Suter Lilian
- Sutherland Clare
- Sverdrup Therese
- Szabelska Anna
- Szala Anna
- Szaszi Barnabas
- Szecsi Peter
- Szwed Paulina
- Sánchez Oscar
- Taber Jennifer
- Taephant Nattasuda
- Tajchman Zuzanna
- Tamnes Christian
- Tan Chrystalle
- Tan Kok Wei
- Tatachari Srinivasan
- Tcherkassof Anna
- Tejada Rivera María del Carmen M. C.
- Terskova Maria
- Theodoropoulou Andriana
- Thirkettle Martin
- Thomas Andrew
- Thommesen Katrine Krabbe
- Thorstenson Christopher
- Tiantian Dong
- Tidwell Natasha
- Todsen Anna Louise
- Topor Marta
- Tops Mattie
- Toro Mónica
- Torres Adriana Olaya
- Torunsky Nathan
- Tran Ulrich
- Travaglino Giovanni
- Tressoldi Patrizio
- Tullett Alexa
- Turiegano Enrique
- Tümer Murat
- Uchida Yukiko
- Uittenhove Kim
- Urban Jan
- Urooj Anum
- Urry Heather
- Uttley Jim
- Uusberg Andero
- Vadillo Miguel
- Vaidis David
- Valderrama Eugenio
- Valentova Jaroslava
- Valentova Jaroslava Varella
- Vally Zahir
- van de Ven Niels
- Van der Linden Nicolas
- Van Doren Natalia
- van Schie Kevin
- van Steenkiste I.
- van Zyl Casper
- Vanman Eric
- Vanpaemel Wolf
- Varella Marco
- Vargas-Nieto Juan Camilo
- Vasilev Martin
- Vatakis Argiro
- Vaughn Leigh Ann
- Vazire Simine
- Vdovic Milica
- Vega Diego
- Verbruggen Frederick
- Vergauwe Evie
- Verharen Jeroen
- Verschuere Bruno
- Vezirian Kevin
- Vianello Michelangelo
- Vieira Luc
- Vilar Roosevelt
- Vilares Iris
- Villar Sergio
- Vilsmeier Johannes
- Vingerhoets Ad
- Vintr Jáchym
- Volz Leonhard
- von Bastian Claudia
- Voracek Martin
- Vranka Marek
- Vuoskoski Jonna
- Vásquez-Amézquita Milena
- Wagemans Fieke
- Walczak Radoslaw
- Wang Chunhui
- Wang Hsiao-Hsin
- Wang Ke
- Warmelink Lara
- Weinstein Netta
- Weissgerber Sophia
- Westerlund Minja
- Westgate Erin
- White David
- Whitt Cassie
- Wichman Aaron
- Wielgus Magdalena
- Willis Megan
- Wilson John
- Wilson John Paul
- Wissink Joeri
- Wlodarczyk Anna
- Wolf Daniel
- Wolfe Kelly
- Wu Qi
- Wu Yang
- Xiao Qinyu
- Xie Sally
- Yamada Yuki
- Yan Wen-Jing
- Yang Xin
- Yao Elvin
- Yeung Siu Kit
- Yu Karen
- Zabel Chelsea
- Zakharov Ilya
- Zdybek Przemysław
- Zettler Ingo
- Zheng Michelle Xue
- Ziano Ignazio
- Zickfeld Janis
- Zorjan Saša
- Zrimsek Miha
- Zsido Andras
- Álvarez-Solas Sara
- Çoksan Sami
- Çolak Tuğba Seda
- Özdoğru Asil
- Özdoğru Asil Ali
- Čadek Martin
- Ścigała Karolina
- Śmieja Magdalena
- Šakan Dušana
- Šebeňa René
- Štrukelj Eva
- Žuro Barbara
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
The COVID-19 pandemic has increased negative emotions and decreased positive emotions globally. Left unchecked, these emotional changes might have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we tested the effectiveness of reappraisal, an emotion-regulation strategy that modifies how one thinks about a situation. Participants from 87 countries and regions (n = 21,644) were randomly assigned to one of two brief reappraisal interventions (reconstrual or repurposing) or one of two control conditions (active or passive). Results revealed that both reappraisal interventions (vesus both control conditions) consistently reduced negative emotions and increased positive emotions across different measures. Reconstrual and repurposing interventions had similar effects. Importantly, planned exploratory analyses indicated that reappraisal interventions did not reduce intentions to practice preventive health behaviours. The findings demonstrate the viability of creating scalable, low-cost interventions for use around the world
Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Abate Yohannes Habtegiorgis
- Abbas Jaffar
- Abbasi Madineh Akram
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd-Rabu Rami
- Abdelmasseh Michael
- Abdollahi Mohammad
- Abdollahi Mozhan
- Abdollahifar Mohammad-Amin
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abedi Aidin
- Abedi Vida
- Abeldaño Zuñiga Roberto Ariel
- Abidi Hassan
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Aboyans Victor
- Abrha Woldu Aberhe
- Abu-Gharbieh Eman
- Abualhasan Ahmed
- Aburuz Salahdein
- Adamu Lawan Hassan
- Addo Isaac Yeboah
- Adebayo Oladimeji M
- Adekanmbi Victor
- Adekiya Tayo Alex
- Adikusuma Wirawan
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afework Tsion
- Afolabi Aanuoluwapo Adeyimika
- Afraz Ali
- Afzal Saira
- Aghamiri Shahin
- Agodi Antonella
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Sajjad
- Ahmadzade Amir Mahmoud
- Ahmed Ali
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Jivan Qasim
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Ajumobi Olufemi
- Akade Seyed Esma'il
- Akbari Morteza
- Akbarialiabad Hossein
- Akhlaghi Shiva
- Akinosoglou Karolina
- Akinyemi Rufus Olusola
- Akonde Maxwell
- Al Hasan Syed Mahfuz
- AL-Ahdal Tareq Mohammed Ali
- Al-amer Rasmieh Mustafa
- Al-Gheethi Adel Ali Saeed
- Al-Omari Basem
- Al-Shahi Salman Rustam
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Alahdab Fares
- Albashtawy Mohammed
- AlBataineh Mohammad T
- Aldawsari Khalifah A
- Alemi Hediyeh
- Alemi Sharifullah
- Algammal Abdelazeem M
- Alhalaiqa Fadwa Alhalaiqa Naji
- Alhassan Robert Kaba
- Ali Abid
- Ali Endale Alemayehu
- Ali Liaqat
- Ali Mohammed Usman
- Ali Musa Mohammed
- Ali Rafat
- Ali Shahid
- Ali Syed Shujait Shujait
- Ali Zahid
- Alif Sheikh Mohammad
- Alimohamadi Yousef
- Aliyi Ahmednur Adem
- Aljofan Mohamad
- Aljunid Syed Mohamed
- Alladi Suvarna
- Almazan Joseph Uy
- Almustanyir Sami
- Alqahtani Jaber S
- Alqasmi Ibrahim
- Alqutaibi Ahmed Yaseen
- Altaany Zaid
- Altirkawi Khalid A
- Alvis-Guzman Nelson
- Aly Hany
- Aly Safwat
- Alzoubi Karem H
- Amani Reza
- Amindarolzarbi Alireza
- Amiri Sohrab
- Amirzade-Iranaq Mohammad Hosein
- Amu Hubert
- Amugsi Dickson A
- Amusa Ganiyu Adeniyi
- Amzat Jimoh
- Ancuceanu Robert
- Anderlini Deanna
- Anderson David B
- Andrei Catalina Liliana
- Androudi Sofia
- Angappan Dhanalakshmi
- Angesom Teklit W
- Anil Abhishek
- Ansari-Moghaddam Alireza
- Anwer Razique
- Arafat Mosab
- Aravkin Aleksandr Y
- Areda Demelash
- Ariffin Hany
- Arifin Hidayat
- Arkew Mesay
- Arooj Mahwish
- Artamonov Anton A
- Artanti Kurnia Dwi
- Aruleba Raphael Taiwo
- Asadi-Pooya Ali A
- Asena Tilahun Ferede
- Asghari-Jafarabadi Mohammad
- Ashraf Muhammad
- Ashraf Tahira
- Atalell Kendalem Asmare
- Athari Seyyed Shamsadin
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- Shams-Beyranvand Mehran
- Shamsi Mohammad Anas
- Shanawaz Mohd
- Sharath Medha
- Sharfaei Sadaf
- Sharifan Amin
- Sharma Manoj
- Sharma Rajesh
- Shashamo Bereket Beyene
- Shayan Maryam
- Sheikhi Rahim Ali
- Shekhar Shashank
- Shen Jiabin
- Shenoy Suchitra M
- Shetty Pavanchand H
- Shiferaw Desalegn Shiferaw
- Shigematsu Mika
- Shiri Rahman
- Shittu Aminu
- Shivakumar K M
- Shokri Fereshteh
- Shool Sina
- Shorofi Seyed Afshin
- Shrestha Sunil
- Siankam Tankwanchi Akhenaten Benjamin
- Siddig Emmanuel Edwar
- Sigfusdottir Inga Dora
- Silva João Pedro
- Silva Luís Manuel Lopes Rodrigues
- Sinaei Ehsan
- Singh Balbir Bagicha
- Singh Garima
- Singh Paramdeep
- Singh Surjit
- Sirota Sarah Brooke
- Sivakumar Shravan
- Sohag Abdullah Al Mamun
- Solanki Ranjan
- Soleimani Hamidreza
- Solikhah Solikhah
- Solomon Yerukneh
- Solomon Yonatan
- Song Suhang
- Song Yimeng
- Sotoudeh Houman
- Spartalis Michael
- Stark Benjamin A
- Starnes Joseph R
- Starodubova Antonina V
- Stein Dan J
- Steiner Timothy J
- Steinmetz Jaimie D
- Stovner Lars Jacob
- Suleman Muhammad
- Suliankatchi Abdulkader Rizwan
- Sultana Abida
- Sun Jing
- Sunkersing David
- Sunny Angel
- Susianti Hani
- Swain Chandan Kumar
- Szeto Mindy D
- Tabarés-Seisdedos Rafael
- Tabatabaei Seyyed Mohammad
- Tabatabai Shima
- Tabish Mohammad
- Taheri Majid
- Tahvildari Azin
- Tajbakhsh Ardeshir
- Tampa Mircea
- Tamuzi Jacques JL Lukenze
- Tan Ker-Kan
- Tang Haosu
- Tareke Minale
- Tarigan Ingan Ukur
- Tat Nathan Y
- Tat Vivian Y
- Tavakoli Oliaee Razieh
- Tavangar Seyed Mohammad
- Tavasol Arian
- Tefera Yibekal Manaye
- Tehrani-Banihashemi Arash
- Temesgen Worku Animaw
- Temsah Mohamad-Hani
- Teramoto Masayuki
- Tesfaye Amensisa Hailu
- Tesfaye Edosa Geta
- Tesler Riki
- Thakali Ocean
- Thangaraju Pugazhenthan
- Thapa Rajshree
- Thapar Rekha
- Thomas Nikhil Kenny
- Thrift Amanda G
- Ticoalu Jansje Henny Vera
- Tillawi Tala
- Toghroli Razie
- Tonelli Marcello
- Tovani-Palone Marcos Roberto
- Traini Eugenio
- Tran Nghia Minh
- Tran Ngoc-Ha
- Tran Phu Van
- Tromans Samuel Joseph
- Truelsen Thomas Clement
- Truyen Thien Tan Tri Tai
- Tsatsakis Aristidis
- Tsegay Guesh Mebrahtom
- Tsermpini Evangelia Eirini
- Tualeka Abdul Rohim
- Tufa Derara Girma
- Ubah Chukwudi S
- Udoakang Aniefiok John
- Ulhaq Inam
- Umair Muhammad
- Umakanthan Srikanth
- Umapathi Krishna Kishore
- Unim Brigid
- Unnikrishnan Bhaskaran
- Vaithinathan Asokan Govindaraj
- Vakilian Alireza
- Valadan Tahbaz Sahel
- Valizadeh Rohollah
- Van den Eynde Jef
- Vart Priya
- Varthya Shoban Babu
- Vasankari Tommi Juhani
- Vaziri Siavash
- Vellingiri Balachandar
- Venketasubramanian Narayanaswamy
- Verras Georgios-Ioannis
- Vervoort Dominique
- Villafañe Jorge Hugo
- Villani Leonardo
- Vinueza Veloz Andres Fernando
- Viskadourou Maria
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Volovat Simona Ruxandra
- Vos Theo
- Vu Loc Tri
- Vujcic Isidora S
- Wagaye Birhanu
- Waheed Yasir
- Wahood Waseem
- Walde Mandaras Tariku
- Wang Fang
- Wang Shu
- Wang Yanzhong
- Wang Yuan-Pang
- Waqas Muhammad
- Waris Abdul
- Weerakoon Kosala Gayan
- Weintraub Robert G
- Weldemariam Abrha Hailay
- Westerman Ronny
- Whisnant Joanna L
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Willekens Barbara
- Wilner Lauren B
- Winkler Andrea Sylvia
- Wolfe Charles D A
- Wu Ai-Min
- Wulf Hanson Sarah
- Xu Suowen
- Xu Xiaoyue
- Yadollahpour Ali
- Yaghoubi Sajad
- Yahya Galal
- Yamagishi Kazumasa
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Yehualashet Sisay Shewasinad
- Yeshaneh Alex
- Yesiltepe Metin
- Yi Siyan
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- You Yuyi
- Younis Mustafa Z
- Yu Chuanhua
- Yusuf Hadiza
- Zadey Siddhesh
- Zahedi Mohammad
- Zakham Fathiah
- Zaki Nazar
- Zali Alireza
- Zamagni Giulia
- Zand Ramin
- Zandieh Ghazal G Z
- Zangiabadian Moein
- Zarghami Amin
- Zastrozhin Mikhail Sergeevich
- Zeariya Mohammed G M
- Zegeye Zelalem Banjaw
- Zeukeng Francis
- Zhai Chunxia
- Zhang Chen
- Zhang Haijun
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhao Yang
- Zheng Peng
- Zhou Hengxing
- Zhu Bin
- Zhumagaliuly Abzal
- Zielińska Magdalena
- Zikarg Yossef Teshome
- Zoladl Mohammad
- Ärnlöv Johan
- Publication venue
- Elsevier
- Publication date
- 01/04/2024
- Field of study
BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed
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Sex-specific metabolic functions of adipose Lipocalin-2.
- Author
- Publication venue
- eScholarship, University of California
- Publication date
- 01/12/2019
- Field of study
OBJECTIVE:Lipocalin-2 (LCN2) is a secreted protein involved in innate immunity and has also been associated with several cardiometabolic traits in both mouse and human studies. However, the causal relationship of LCN2 to these traits is unclear, and most studies have examined only males. METHODS:Using adeno-associated viral vectors we expressed LCN2 in either adipose or liver in a tissue specific manner on the background of a whole-body Lcn2 knockout or wildtype mice. Metabolic phenotypes including body weight, body composition, plasma and liver lipids, glucose homeostasis, insulin resistance, mitochondrial phenotyping, and metabolic cage studies were monitored. RESULTS:We studied the genetics of LCN2 expression and associated clinical traits in both males and females in a panel of 100 inbred strains of mice (HMDP). The natural variation in Lcn2 expression across the HMDP exhibits high heritability, and genetic mapping suggests that it is regulated in part by Lipin1 gene variation. The correlation analyses revealed striking tissue dependent sex differences in obesity, insulin resistance, hepatic steatosis, and dyslipidemia. To understand the causal relationships, we examined the effects of expression of LCN2 selectively in liver or adipose. On a Lcn2-null background, LCN2 expression in white adipose promoted metabolic disturbances in females but not males. It acted in an autocrine/paracrine manner, resulting in mitochondrial dysfunction and an upregulation of inflammatory and fibrotic genes. On the other hand, on a null background, expression of LCN2 in liver had no discernible impact on the traits examined despite increasing the levels of circulating LCN2 more than adipose LCN2 expression. The mechanisms underlying the sex-specific action of LCN2 are unclear, but our results indicate that adipose LCN2 negatively regulates its receptor, LRP2 (or megalin), and its repressor, ERα, in a female-specific manner and that the effects of LCN2 on metabolic traits are mediated in part by LRP2. CONCLUSIONS:Following up on our population-based studies, we demonstrate that LCN2 acts in a highly sex- and tissue-specific manner in mice. Our results have important implications for human studies, emphasizing the importance of sex and the tissue source of LCN2
Recommended from our members
Sex-specific metabolic functions of adipose Lipocalin-2.
- Author
- Publication venue
- eScholarship, University of California
- Publication date
- 01/12/2019
- Field of study
OBJECTIVE:Lipocalin-2 (LCN2) is a secreted protein involved in innate immunity and has also been associated with several cardiometabolic traits in both mouse and human studies. However, the causal relationship of LCN2 to these traits is unclear, and most studies have examined only males. METHODS:Using adeno-associated viral vectors we expressed LCN2 in either adipose or liver in a tissue specific manner on the background of a whole-body Lcn2 knockout or wildtype mice. Metabolic phenotypes including body weight, body composition, plasma and liver lipids, glucose homeostasis, insulin resistance, mitochondrial phenotyping, and metabolic cage studies were monitored. RESULTS:We studied the genetics of LCN2 expression and associated clinical traits in both males and females in a panel of 100 inbred strains of mice (HMDP). The natural variation in Lcn2 expression across the HMDP exhibits high heritability, and genetic mapping suggests that it is regulated in part by Lipin1 gene variation. The correlation analyses revealed striking tissue dependent sex differences in obesity, insulin resistance, hepatic steatosis, and dyslipidemia. To understand the causal relationships, we examined the effects of expression of LCN2 selectively in liver or adipose. On a Lcn2-null background, LCN2 expression in white adipose promoted metabolic disturbances in females but not males. It acted in an autocrine/paracrine manner, resulting in mitochondrial dysfunction and an upregulation of inflammatory and fibrotic genes. On the other hand, on a null background, expression of LCN2 in liver had no discernible impact on the traits examined despite increasing the levels of circulating LCN2 more than adipose LCN2 expression. The mechanisms underlying the sex-specific action of LCN2 are unclear, but our results indicate that adipose LCN2 negatively regulates its receptor, LRP2 (or megalin), and its repressor, ERα, in a female-specific manner and that the effects of LCN2 on metabolic traits are mediated in part by LRP2. CONCLUSIONS:Following up on our population-based studies, we demonstrate that LCN2 acts in a highly sex- and tissue-specific manner in mice. Our results have important implications for human studies, emphasizing the importance of sex and the tissue source of LCN2
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Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy.
- Author
- Anum Diana
- Attie Alan D
- Cao Yang
- Carroll Luke
- Chella Krishnan Karthickeyan
- Churchill Gary A
- El Hachem Elie-Julien
- Gerdes Gyuricza Isabela
- James David E
- Kaczor-Urbanowicz Karolina Elżbieta
- Keller Mark P
- Lee Chi Fung
- Light Christine
- Lusis Aldons J
- Pan Calvin
- Parker Benjamin
- Patel Sanjeet G
- Pellegrini Matteo
- Rosenthal Nadia A
- Seldin Marcus M
- Shravah Varun
- Vegas Alexis Diaz
- Publication venue
- eScholarship, University of California
- Publication date
- 01/06/2023
- Field of study
Mitochondria play an important role in both normal heart function and disease etiology. We report analysis of common genetic variations contributing to mitochondrial and heart functions using an integrative proteomics approach in a panel of inbred mouse strains called the Hybrid Mouse Diversity Panel (HMDP). We performed a whole heart proteome study in the HMDP (72 strains, n=2-3 mice) and retrieved 848 mitochondrial proteins (quantified in ≥50 strains). High-resolution association mapping on their relative abundance levels revealed three trans-acting genetic loci on chromosomes (chr) 7, 13 and 17 that regulate distinct classes of mitochondrial proteins as well as cardiac hypertrophy. DAVID enrichment analyses of genes regulated by each of the loci revealed that the chr13 locus was highly enriched for complex-I proteins (24 proteins, P=2.2E-61), the chr17 locus for mitochondrial ribonucleoprotein complex (17 proteins, P=3.1E-25) and the chr7 locus for ubiquinone biosynthesis (3 proteins, P=6.9E-05). Follow-up high resolution regional mapping identified NDUFS4, LRPPRC and COQ7 as the candidate genes for chr13, chr17 and chr7 loci, respectively, and both experimental and statistical analyses supported their causal roles. Furthermore, a large cohort of Diversity Outbred mice was used to corroborate Lrpprc gene as a driver of mitochondrial DNA (mtDNA)-encoded gene regulation, and to show that the chr17 locus is specific to heart. Variations in all three loci were associated with heart mass in at least one of two independent heart stress models, namely, isoproterenol-induced heart failure and diet-induced obesity. These findings suggest that common variations in certain mitochondrial proteins can act in trans to influence tissue-specific mitochondrial functions and contribute to heart hypertrophy, elucidating mechanisms that may underlie genetic susceptibility to heart failure in human populations
Risk of COVID-19 after natural infection or vaccinationResearch in context
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- A. Lina Rosengren
- Abram Burgher
- Adam B. Brosz
- Adam Rosen
- Adam Schwartz
- Adriana Sordo Duran
- Adrienna Marquez
- Adrienne E. Shapiro
- Aeiress Duhart
- Afsoon Roberts
- Albert Liu
- Alejandro Hoberman
- Alejandro Quintín Barrat Hernández
- Alex Greninger
- Alexander Clark
- Alfredo Gilberto Guerreros Benavides
- Alice McGarry
- Alicia Arrazcaeta
- Alisha Lutat
- Alison Bondell
- Alison Pellecchia
- Allie Oplinger
- Allison Green
- Allison O'Brien
- Alpa Patel
- Alyssa-Kay Peay
- Amanda Horn
- Amanda Lilienthal
- Amanda Occhino
- Amanda Philyaw
- Amaran Moodley
- Amber Grant
- Amber Stanford
- Amesika Nyaku
- Amie Shannon
- Amina Z. Haggag
- Amit Paliwal
- Amy Caldwell
- Amy Chamberlain
- Amy Dye
- Amy Falk
- Amy Kelley
- Amy Medina
- Amy Potts
- Amy Salzl
- Amy Sherman
- Amy Starr
- Amy Thompson
- Andrea Berry
- Andrea Clement
- Andrea Wendrow
- Andrea Zimmer
- Andres Bran
- Andres Camacho-Gonzalez
- Andrew Lauria
- Andrew McConnell
- Andrew McWilliams
- Anelgine C. Yoon
- Angela Lee
- Angela R. Branche
- Angelica Kottkamp
- Angella Webb
- Ann M. Milliken
- Ann R. Falsey
- Anna S. Lok
- Anna Wald
- Anne Marit de Groot
- Anne-Marie Rick
- Annette R. Bennett
- Annie Ciambruschini
- Annie Luetkemeyer
- Anthony Kim
- Anum Abbas
- Anyela Lara
- April Pixler
- Ariana C. Stanton
- Arthur L. Zemanek
- Asha Inniss
- Ashley Kennedy
- Ashley Perez
- Ashley Warden
- Asif Noor
- Atoya Adams
- Aurelio Cruz-Valdez
- Austin Chan
- Austin Swanson
- Ayanna Walters
- Ayoade Avworo
- Bailey Jordan
- Barbara Corral
- Barbara Rizzardi
- Barbara Rizzardi
- Barbara S. Taylor
- Barry S. Zingman
- Barton G. Williams
- Beatriz Grinsztejn
- Becky Martinez
- Ben Ladner
- Benjamin Eckhardt
- Benjamin J. Luft
- Bernard Grunstra
- Beth Safirstein
- Bethanie Wilkinson
- Beverly E. Sha
- Beverly Ewing
- Bindu Balani
- Blanca Gomez
- Bo Shopsin
- Boerries Brandenburg
- Brandie Taylor
- Brandon J. Essink
- Brandy Ball
- Breanz Watkins
- Brenda Dorcely
- Brendan Levy
- Brett Gray
- Brett Leav
- Brian D.W. Chow
- Brit Sovic
- Brittany Feijoo
- Brittany Stewart
- Bruce C. Gebhardt
- Bruce G. Rankin
- Bruce McClenathan
- Bruno Valenti
- Bryan Gordon
- C. Mary Healy
- Caitlin J. Guiney
- Caitlin Moran
- Candace Smith
- Candice Montros
- Carina A. Rodriguez
- Carl Fichtenbaum
- Carl P. Griffin
- Carlos A. Fierro
- Carlos del Rio
- Carlos Lopez
- Carlos Malvestutto
- Carmel B. Dyer
- Carmen A. Paez
- Carmen Amador
- Carmen D. Zorrilla
- Carmen Medina
- Carol Ann Linebarger
- Carol Kauffman
- Carol L. Mitchell
- Carolene Stephenson
- Caroline Greene
- Carolyn Scatamacchia
- Carolyn Tran
- Carrie Johnston
- Carrie Sopher
- Catherine A. Bunce
- Catherine Mary Healy
- Catherine Q. Gular
- Cathy Laflan
- Cecilia McKeown-Bragas
- Celia Gonzalez
- Celia Maxwell
- Charles Harper
- Charles M. Fogarty
- Charlotte-Paige Rolle
- Charnell Cromer
- Chelsea Miles
- Chelsie Nutsch
- Chelsie Nutsch
- Chen S. Tan
- Chenchen Yu
- Cheryl Nuss
- Cheryl Young
- Chimeremma Nnadi
- Chinar Desai
- Christian Tomaszewski
- Christina A. Rostad
- Christina Bacher
- Christina Kennelly
- Christine Akamine
- Christine B. Turley
- Christine Hull
- Christine Wilson
- Christopher Carpenter
- Christopher Dedon
- Christopher Galloway
- Christopher Matich
- Christy Schmeck
- Christy Sweet
- Clarence B. Creech II
- Clarisse Baudelaire
- Claudia De La Matta Rodriguez
- Claudia Espinosa
- Claudio Nuñez Lagos
- Clint C. Guillory
- Clint Wilson
- Codi M. Anthony
- Colleen F. Kelley
- Colleen Jacobsen
- Connie Moya
- Cora Sonnier
- Corey G. Anderson
- Corey M. Chen
- Cornell Calinescu
- Corrina Pavetto
- Cortney Burch
- Cory J. Huffine
- Craig Dietz
- Cristina Cicogna
- Crystal Rowell
- Cynthia Becher Strout
- Cynthia Brown
- Cynthia Bueno
- Cynthia L. Gay
- Cynthia L. Monaco
- Cynthia Montano-Pereira
- Cyrus Hoseyni
- Dakotah C. Lane
- Dalia Tovar
- Daniel Duncanson
- Daniel Hoft
- Daniel Kaul
- Daniel S. Graciaa
- Daniel T. Lawler
- Daniela Pineda Méndez
- Danielle Raley
- Danny Sugimoto
- Danyel Johnson
- Darlene Bartilucci
- David B. Musante
- David Beckmann
- David Browder
- David Dellaero
- David Fitz-Patrick
- David Halpert
- David I. Bernstein
- David J. Diemert
- David J. Ensz
- David Kline
- David L. Fried
- David Metzger
- David Pampe
- David Pitrak
- David R. Andes
- David Rosenberg
- David Tatelbaum
- David Wohl
- Dawn Furey
- Dawn Robison
- Dean Follmann
- Dean M. Boswell
- Deanna Cooper
- Debora Dunbar
- Deborah A. Theodore
- Deborah Murray
- Debra B. Schroeck
- Delia Bullock
- Denis Tarakjian
- Denise Casey
- Denise Roadman
- Denise Sample
- Denisse Alejandra González Estrada
- Derek Lewis
- Derek M. Smith
- Destiny S. Heinzig-Cartwright
- Diana Badillo
- Diana F. Florescu
- Diana Vegas
- Dianca Sierra
- Diane H. Johnson
- Dilek Ince
- Dima Dandachi
- Dirk Heerwegh
- Dolores Rijos
- Donald M. Brandon
- Donald Quinn
- Donna Percy
- Doris Franco-Vitteri
- Douglas S. Denham
- E. Javier Pretell Alva
- Edgar Garcia
- Edith Swann
- Eduardo Gabriel Vázquez Saldaña
- Edward C. Jones-López
- Edward E. Walsh
- Edward Ellerbeck
- Edward M. Tavel Jr.
- Elham Ghadishah
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- Elwaleed Elnagar
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- Fan Yang
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- Jeremy Ackermann
- Jeremy Brown
- Jerome Custers
- Jerome G. Naifeh
- Jesse L. Clark
- Jessica E. Justman
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- Jewel J. White
- Jill Blumenthal
- Jill Kessler
- Jill York
- Jim Callis
- Joan Rothenberg
- Joanne L. Billings
- Jocelyn Zuleica Olmos Vega
- Jodi Meck
- Joel Solis
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- John A. Kirby
- John J. Treanor
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- John W. McGettigan Jr.
- John Witbeck
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- Jonlyn McGettigan
- Jordan Coslet
- Jordan L. Whatley
- Jorge A. Benitez
- Jorge A. Chacón
- Jorge Caso
- Jorge F. Méndez Galván
- Jose A. Bazan
- Jose C. Mancilla
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- Uriel R. Felsen
- Valentine M. Ebuh
- Valeria D. Cantos
- Valerie K. Arnold
- Vanessa Abad
- Vanessa Raabe
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- Veronica Garcia-Fragoso
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- Victoria Engler
- Victoria Mosteller
- Victoria R. Anderson
- Vida Veronica Ruiz Herrera
- Vincent Huynh
- Vincent Mirkil
- Vivek Rajasekhar
- Viviana Gonzalez
- Vladimir Berthaud
- Walter Patton
- Wanda Ramon
- Waseem Chughtai
- Wayne L. Harper
- Wayne Woo
- Wendell Lewis
- Wendell Lewis III
- Wendy A. Keitel
- Wesley Campbell
- Wesley Van Ever
- Westly Keating
- Whitney West
- Will Hernandez
- William B. Davis
- William B. Smith
- William H. Jones
- William Jennings
- William Kirby
- William P. Silver
- William R. Hartman
- William S. Davis Jr.
- William Schnitz
- William Seger
- Winniberg Stephany Alvarez León
- Winston Cavert
- Xiaomi Tong
- Yaa D. Oppong
- Yi H. Wu
- Ying Huang
- Yogesh K. Paliwal
- Youyi Fong
- Yunda Huang
- Yunda Huang
- Yvonne Davis
- Zachary Bittner
- Zainab Rizvi
- Zindy Yazmín Zárate Hinojosa
- Zudi-Mwak Takizala
- Publication venue
- Elsevier
- Publication date
- 01/10/2023
- Field of study
Summary: Background: While vaccines have established utility against COVID-19, phase 3 efficacy studies have generally not comprehensively evaluated protection provided by previous infection or hybrid immunity (previous infection plus vaccination). Individual patient data from US government-supported harmonized vaccine trials provide an unprecedented sample population to address this issue. We characterized the protective efficacy of previous SARS-CoV-2 infection and hybrid immunity against COVID-19 early in the pandemic over three-to six-month follow-up and compared with vaccine-associated protection. Methods: In this post-hoc cross-protocol analysis of the Moderna, AstraZeneca, Janssen, and Novavax COVID-19 vaccine clinical trials, we allocated participants into four groups based on previous-infection status at enrolment and treatment: no previous infection/placebo; previous infection/placebo; no previous infection/vaccine; and previous infection/vaccine. The main outcome was RT-PCR-confirmed COVID-19 >7–15 days (per original protocols) after final study injection. We calculated crude and adjusted efficacy measures. Findings: Previous infection/placebo participants had a 92% decreased risk of future COVID-19 compared to no previous infection/placebo participants (overall hazard ratio [HR] ratio: 0.08; 95% CI: 0.05–0.13). Among single-dose Janssen participants, hybrid immunity conferred greater protection than vaccine alone (HR: 0.03; 95% CI: 0.01–0.10). Too few infections were observed to draw statistical inferences comparing hybrid immunity to vaccine alone for other trials. Vaccination, previous infection, and hybrid immunity all provided near-complete protection against severe disease. Interpretation: Previous infection, any hybrid immunity, and two-dose vaccination all provided substantial protection against symptomatic and severe COVID-19 through the early Delta period. Thus, as a surrogate for natural infection, vaccination remains the safest approach to protection. Funding: National Institutes of Health
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Risk of COVID-19 after natural infection or vaccinationResearch in context
- Author
- Abad Vanessa
- Abate Getahun
- Abbas Anum
- Ackerman Jamie
- Ackerman Ronald
- Ackermann Jeremy
- Adams Atoya
- Adams Mark S.
- Adams Michael R.
- Adelglass Jeffrey
- Afework Sarah
- Ahmad Nina
- Akamine Christine
- Ake Julie A.
- Al-Ibrahim Mohamed S.
- Albert Gary
- Alcaide Maria L.
- Alderson Nathan
- Aleman Lily
- Alemán José O.
- Allaw Mohammed
- Alva E. Javier Pretell
- Alvarado Hilario
- Amador Carmen
- Andersen James
- Anderson Corey G.
- Anderson Evan J.
- Anderson Victoria R.
- Andes David R.
- Andrasik Michele P.
- Andree Stephanie
- Andrews Jeb
- Andriesen Jessica G.
- Andriulis Victoria
- Ansel Jessica L.
- Anthony Codi M.
- Antwi Mohammed
- Arduino Roberto C.
- Aristy Florida
- Arnold Valerie K.
- Arrazcaeta Alicia
- Atmar Robert L.
- Avworo Ayoade
- Bacher Christina
- Baden Lindsey R.
- Badillo Diana
- Bainbridge Emma
- Baka Michele
- Baker Sherrie
- Balani Bindu
- Ball Brandy
- Bances Karla Beatriz Tafur
- Baron Mira
- Barranco-Santana Elizabeth
- Bartilucci Darlene
- Bashour Jennifer
- Batteiger Teresa A.
- Baudelaire Clarisse
- Bazan Jose A.
- Becerra Maria G.
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- Belhorn Linda R.
- Benavides Alfredo Gilberto Guerreros
- Beninati Genevieve
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- Bennett Annette R.
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- Beresnev Tatiana
- Berman Megan
- Bermudez Maria I.
- Bernard Marcia
- Bernstein David I.
- Berry Andrea
- Berry Jennifer
- Berthaud Vladimir
- Bialobok Kristin
- Billings Joanne L.
- Bittner Zachary
- Blevins Jeanne
- Blumenthal Jill
- Boas Rebecca
- Bocchini Joseph
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- Boscia Joseph
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- Villegas Marysol
- Vingerhoets Johan
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- Vrbicky Keith W.
- Wahlin Tami
- Wakefield Paul H.
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- Walker James
- Walker Shannon
- Walsh Edward E.
- Walsh Mary C.
- Walsh Stephen R.
- Walsh Stephen R.
- Walter Emmanuel B.
- Walters Ayanna
- Wang Tina
- Warden Ashley
- Waters Michael
- Watkins Breanz
- Webb Angella
- Webster Hala
- Weidler Jessica L.
- Weiss Thomas
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- Wendell Lewis III
- Wendrow Andrea
- Werne Melody
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- Whatley Jordan L.
- Whitaker Jennifer A.
- White Jewel J.
- White Julie
- White Toni
- Wijewardane Priyantha N.
- Wilkin Timothy
- Wilkinson Bethanie
- William S. Davis Jr
- Williams Barton G.
- Williams Hayes
- Williams Samantha
- Wilson Christine
- Wilson Clint
- Wilson Greg
- Wilson Natasha
- Winbigler Jennifer
- Winkle Peter J.
- Winokur Patricia L.
- Witbeck John
- Wohl David
- Woo Wayne
- Woodside Leana
- Wortman Glenn
- Wu Yi H.
- Wylie Paul E.
- Yang Fan
- Yang Kinara S.
- Yoon Anelgine C.
- York Jill
- Young Cheryl
- Yu Chenchen
- Yusin Joseph
- Zapata Luz
- Zash Rebecca
- Zegarra Eneyda Giuvanela Llerena
- Zemanek Arthur L.
- Zenlea Kate
- Zepeda Karla
- Zervos Marcus J.
- Zhai Nan
- Zhang Kevin
- Zhou James
- Zimmer Andrea
- Zingman Barry S.
- Zorrilla Carmen D.
- Áñez Germán
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/10/2023
- Field of study
Background: While vaccines have established utility against COVID-19, phase 3 efficacy studies have generally not comprehensively evaluated protection provided by previous infection or hybrid immunity (previous infection plus vaccination). Individual patient data from US government-supported harmonized vaccine trials provide an unprecedented sample population to address this issue. We characterized the protective efficacy of previous SARS-CoV-2 infection and hybrid immunity against COVID-19 early in the pandemic over three-to six-month follow-up and compared with vaccine-associated protection. Methods: In this post-hoc cross-protocol analysis of the Moderna, AstraZeneca, Janssen, and Novavax COVID-19 vaccine clinical trials, we allocated participants into four groups based on previous-infection status at enrolment and treatment: no previous infection/placebo; previous infection/placebo; no previous infection/vaccine; and previous infection/vaccine. The main outcome was RT-PCR-confirmed COVID-19 >7–15 days (per original protocols) after final study injection. We calculated crude and adjusted efficacy measures. Findings: Previous infection/placebo participants had a 92% decreased risk of future COVID-19 compared to no previous infection/placebo participants (overall hazard ratio [HR] ratio: 0.08; 95% CI: 0.05–0.13). Among single-dose Janssen participants, hybrid immunity conferred greater protection than vaccine alone (HR: 0.03; 95% CI: 0.01–0.10). Too few infections were observed to draw statistical inferences comparing hybrid immunity to vaccine alone for other trials. Vaccination, previous infection, and hybrid immunity all provided near-complete protection against severe disease. Interpretation: Previous infection, any hybrid immunity, and two-dose vaccination all provided substantial protection against symptomatic and severe COVID-19 through the early Delta period. Thus, as a surrogate for natural infection, vaccination remains the safest approach to protection. Funding: National Institutes of Health
Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Abate Yohannes Habtegiorgis
- Abbas Jaffar
- Abbasi Madineh Akram
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd-Rabu Rami
- Abdelmasseh Michael
- Abdollahi Mohammad
- Abdollahi Mozhan
- Abdollahifar Mohammad-Amin
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abedi Aidin
- Abedi Vida
- Abeldaño Zuñiga Roberto Ariel
- Abidi Hassan
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Aboyans Victor
- Abrha Woldu Aberhe
- Abu-Gharbieh Eman
- Abualhasan Ahmed
- Aburuz Salahdein
- Adamu Lawan Hassan
- Addo Isaac Yeboah
- Adebayo Oladimeji
- Adekanmbi Victor
- Adekiya Tayo Alex
- Adikusuma Wirawan
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afework Tsion
- Afolabi Aanuoluwapo Adeyimika
- Afraz Ali
- Afzal Saira
- Aghamiri Shahin
- Agodi Antonella
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Sajjad
- Ahmadzade Amir Mahmoud
- Ahmed Ali
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Jivan Qasim
- Ahmed Luai
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Ajumobi Olufemi
- Akade Seyed Esma'Il
- Akbari Morteza
- Akbarialiabad Hossein
- Akhlaghi Shiva
- Akinosoglou Karolina
- Akinyemi Rufus Olusola
- Akonde Maxwell
- Al Hasan Syed Mahfuz
- Al-Ahdal Tareq Mohammed Ali
- Al-Amer Rasmieh Mustafa
- Al-Gheethi Adel Ali Saeed
- Al-Omari Basem
- Al-Shahi Salman Rustam
- Al-Tawfiq Jaffar
- Al-Worafi Yaser Mohammed
- Alahdab Fares
- Albashtawy Mohammed
- Albataineh Mohammad
- Aldawsari Khalifah
- Alemi Hediyeh
- Alemi Sharifullah
- Algammal Abdelazeem
- Alhalaiqa Fadwa Alhalaiqa Naji
- Alhassan Robert Kaba
- Ali Abid
- Ali Endale Alemayehu
- Ali Liaqat
- Ali Mohammed Usman
- Ali Musa Mohammed
- Ali Rafat
- Ali Shahid
- Ali Syed Shujait Shujait
- Ali Zahid
- Alif Sheikh Mohammad
- Alimohamadi Yousef
- Aliyi Ahmednur Adem
- Aljofan Mohamad
- Aljunid Syed Mohamed
- Alladi Suvarna
- Almazan Joseph Uy
- Almustanyir Sami
- Alqahtani Jaber
- Alqasmi Ibrahim
- Alqutaibi Ahmed Yaseen
- Altaany Zaid
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Aly Hany
- Aly Safwat
- Alzoubi Karem
- Amani Reza
- Amindarolzarbi Alireza
- Amiri Sohrab
- Amirzade-Iranaq Mohammad Hosein
- Amu Hubert
- Amugsi Dickson
- Amusa Ganiyu Adeniyi
- Amzat Jimoh
- Ancuceanu Robert
- Anderlini Deanna
- Anderson David
- Andrei Catalina Liliana
- Androudi Sofia
- Angappan Dhanalakshmi
- Angesom Teklit
- Anil Abhishek
- Ansari-Moghaddam Alireza
- Anwer Razique
- Arafat Mosab
- Aravkin Aleksandr
- Areda Demelash
- Ariffin Hany
- Arifin Hidayat
- Arkew Mesay
- Arooj Mahwish
- Artamonov Anton
- Artanti Kurnia Dwi
- Aruleba Raphael Taiwo
- Asadi-Pooya Ali
- Asena Tilahun Ferede
- Asghari-Jafarabadi Mohammad
- Ashraf Muhammad
- Ashraf Tahira
- Atalell Kendalem Asmare
- Athari Seyyed Shamsadin
- Atinafu Bantalem Tilaye Tilaye
- Atorkey Prince
- Atout Maha Moh'D Wahbi
- Atreya Alok
- Aujayeb Avinash
- Avan Abolfazl
- Ayala Quintanilla Beatriz Paulina
- Ayatollahi Haleh
- Ayinde Olatunde
- Ayyoubzadeh Seyed Mohammad
- Azadnajafabad Sina
- Azizi Zahra
- Azizian Khalil
- Azzam Ahmed
- Babaei Mahsa
- Badar Muhammad
- Badiye Ashish
- Baghdadi Soroush
- Bagherieh Sara
- Bai Ruhai
- Baig Atif Amin
- Balakrishnan Senthilkumar
- Balalla Shivanthi
- Baltatu Ovidiu Constantin
- Banach Maciej
- Bandyopadhyay Soham
- Banerjee Indrajit
- Baran Mehmet Firat
- Barboza Miguel
- Barchitta Martina
- Bardhan Mainak
- Barker-Collo Suzanne Lyn
- Barrow Amadou
- Bashash Davood
- Bashiri Hamideh
- Bashiru Hameed Akande
- Basiru Afisu
- Basso João Diogo
- Basu Sanjay
- Batiha Abdul-Monim Mohammad
- Batra Kavita
- Baune Bernhard
- Bedi Neeraj
- Begde Ahmet
- Begum Tahmina
- Behnam Babak
- Behnoush Amir Hossein
- Beiranvand Maryam
- Bekele Alehegn
- Belete Melaku Ashagrie
- Belgaumi Uzma Iqbal
- Bemanalizadeh Maryam
- Bender Rose
- Benfor Bright
- Bennett Derrick
- Bensenor Isabela
- Berice Betyna
- Bettencourt Paulo
- Beyene Kebede
- Bhadra Abhishek
- Bhagat Devidas
- Bhangdia Kayleigh
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhargava Ashish
- Bhaskar Sonu
- Bhat Ajay Nagesh
- Bhat Vivek
- Bhatti Gurjit Kaur
- Bhatti Jasvinder Singh
- Bhatti Rajbir
- Bijani Ali
- Bikbov Boris
- Bilalaga Mariah Malak
- Biswas Atanu
- Bitaraf Saeid
- Bitra Veera
- Bjørge Tone
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Boloor Archith
- Braithwaite Dejana
- Brayne Carol
- Brenner Hermann
- Briko Andrey
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- Tran Ngoc-Ha
- Tran Phu Van
- Tromans Samuel Joseph
- Truelsen Thomas Clement
- Truyen Thien Tan Tri Tai
- Tsatsakis Aristidis
- Tsegay Guesh Mebrahtom
- Tsermpini Evangelia Eirini
- Tualeka Abdul Rohim
- Tufa Derara Girma
- Ubah Chukwudi
- Udoakang Aniefiok John
- Ulhaq Inam
- Umair Muhammad
- Umakanthan Srikanth
- Umapathi Krishna Kishore
- Unim Brigid
- Unnikrishnan Bhaskaran
- Vaithinathan Asokan Govindaraj
- Vakilian Alireza
- Valadan Tahbaz Sahel
- Valizadeh Rohollah
- van den Eynde Jef
- Vart Priya
- Varthya Shoban Babu
- Vasankari Tommi Juhani
- Vaziri Siavash
- Vellingiri Balachandar
- Venketasubramanian Narayanaswamy
- Verras Georgios-Ioannis
- Vervoort Dominique
- Villafañe Jorge Hugo
- Villani Leonardo
- Vinueza Veloz Andres Fernando
- Viskadourou Maria
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Volovat Simona Ruxandra
- Vos Theo
- Vu Loc Tri
- Vujcic Isidora
- Wagaye Birhanu
- Waheed Yasir
- Wahood Waseem
- Walde Mandaras Tariku
- Wang Fang
- Wang Shu
- Wang Yanzhong
- Wang Yuan-Pang
- Waqas Muhammad
- Waris Abdul
- Weerakoon Kosala Gayan
- Weintraub Robert
- Weldemariam Abrha Hailay
- Westerman Ronny
- Whisnant Joanna
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Willekens Barbara
- Wilner Lauren
- Winkler Andrea Sylvia
- Wolfe Charles
- Wu Ai-Min
- Wulf Hanson Sarah
- Xu Suowen
- Xu Xiaoyue
- Yadollahpour Ali
- Yaghoubi Sajad
- Yahya Galal
- Yamagishi Kazumasa
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Yehualashet Sisay Shewasinad
- Yeshaneh Alex
- Yesiltepe Metin
- Yi Siyan
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- You Yuyi
- Younis Mustafa
- Yu Chuanhua
- Yusuf Hadiza
- Zadey Siddhesh
- Zahedi Mohammad
- Zakham Fathiah
- Zaki Nazar
- Zali Alireza
- Zamagni Giulia
- Zand Ramin
- Zandieh Ghazal
- Zangiabadian Moein
- Zarghami Amin
- Zastrozhin Mikhail Sergeevich
- Zeariya Mohammed
- Zegeye Zelalem Banjaw
- Zeukeng Francis
- Zhai Chunxia
- Zhang Chen
- Zhang Haijun
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhao Yang
- Zheng Peng
- Zhou Hengxing
- Zhu Bin
- Zhumagaliuly Abzal
- Zielińska Magdalena
- Zikarg Yossef Teshome
- Zoladl Mohammad
- Ärnlöv Johan
- Publication venue
- Elsevier
- Publication date
- 01/04/2024
- Field of study
International audienc
Search for Scalar Diphoton Resonances in the Mass Range 65−600 GeV with the ATLAS Detector in pp Collision Data at s = 8 TeV
- Author
- Aad Georges
- Abbott Brad
- Abdallah Jalal
- Abdel Khalek Samah
- Abdinov Ovsat
- Aben Rosemarie
- Abi Babak
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Samir
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Agatonovic-Jovin Tatjana
- Aguilar-Saavedra Juan Antonio
- Agustoni Marco
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimoto Ginga
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Josefina
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexandre Gauthier
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Allbrooke Benedict
- Allison Lee John
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew David
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazia
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Patricia
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Stefan
- Andari Nansi
- Andeen Timothy
- Anders Christoph Falk
- Anders Gabriel
- Anderson Kelby
- Andreazza Attilio
- Andrei George Victor
- Anduaga Xabier
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonaki Ariadni
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Apolle Rudi
- Arabidze Giorgi
- Aracena Ignacio
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco Anuar
- Arguin Jean-Francois
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron James
- Arnaez Olivier
- Arnal Vanessa
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- ATLAS Collaboration
- Atlay Naim Bora
- Auerbach Benjamin
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Azuelos Georges
- Azuma Yuya
- Baak Max
- Baas Alessandra
- Bachacou Henri
- Bachas Konstantinos
- Backes Moritz
- Backhaus Malte
- Backus Mayes John
- Badescu Elisabeta
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Keith
- Balek Petr
- Balli Fabrice
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Bansil Hardeep Singh
- Barak Liron
- Barberio Elisabetta Luigia
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Louise
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Bartoldus Rainer
- Barton Adam Edward
- Bartos Pavol
- Bartsch Valeria
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batley Richard
- Battaglia Marco
- Battistin Michele
- Bauer Florian
- Bawa Harinder Singh
- Beattie Michael David
- Beau Tristan
- Beauchemin Pierre-Hugues
- Bechtle Philip
- Beck Hans Peter
- Becker Anne Kathrin
- Becker Sebastian
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bedikian Sourpouhi
- Bednyakov Vadim
- Bee Christopher
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Katharina
- Belanger-Champagne Camille
- Bell Paul
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimiliano
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Garcia Jorge-Armando
- Benjamin Douglas
- Bensinger James
- Bentvelsen Stan
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
- Berghaus Frank
- Beringer Jürg
- Bernard Clare
- Bernat Pauline
- Bernius Catrin
- Bernlochner Florian Urs
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertolucci Federico
- Bertsche Carolyn
- Bertsche David
- Besana Maria Ilaria
- Besjes Geert-Jan
- Bessidskaia Olga
- Bessner Martin Florian
- Besson Nathalie
- Betancourt Christopher
- Bethke Siegfried
- Bhimji Wahid
- Bianchi Riccardo-Maria
- Bianchini Louis
- Bianco Michele
- Biebel Otmar
- Bieniek Stephen Paul
- Bierwagen Katharina
- Biesiada Jed
- Biglietti Michela
- Bilbao De Mendizabal Javier
- Bilokon Halina
- Bindi Marcello
- Binet Sebastien
- Bingul Ahmet
- Bini Cesare
- Black Curtis
- Black James
- Black Kevin
- Blackburn Daniel
- Blair Robert
- Blanchard Jean-Baptiste
- Blazek Tomas
- Bloch Ingo
- Blocker Craig
- Blumenschein Ulrike
- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona Serena
- Bocci Andrea
- Bock Christopher
- Boddy Christopher Richard
- Boehler Michael
- Boek Thorsten Tobias
- Bogdanchikov Alexander
- Bohm Christian
- Boisvert Veronique
- Bold Tomasz
- Boldyrev Alexey
- Bomben Marco
- Bona Marcella
- Boonekamp Maarten
- Borisov Anatoly
- Borissov Guennadi
- Borri Marcello
- Borroni Sara
- Bortfeldt Jonathan
- Bortolotto Valerio
- Boscherini Davide
- Bosman Martine
- Boterenbrood Hendrik
- Boudreau Joseph
- Bouffard Julian
- Bouhova-Thacker Evelina Vassileva
- Boumediene Djamel Eddine
- Bourdarios Claire
- Bousson Nicolas
- Boutouil Sara
- Boveia Antonio
- Boyd James
- Boyko Igor
- Bozic Ivan
- Bracinik Juraj
- Brandt Andrew
- Brandt Gerhard
- Brandt Oleg
- Bratzler Uwe
- Brau Benjamin
- Brau James
- Brazzale Simone Federico
- Brelier Bertrand
- Brendlinger Kurt
- Brennan Amelia Jean
- Brenner Richard
- Bressler Shikma
- Bristow Kieran
- Bristow Timothy Michael
- Britton Dave
- Brochu Frederic
- Brock Ian
- Brock Raymond
- Bronner Johanna
- Brooijmans Gustaaf
- Brooks Timothy
- Brooks William
- Brosamer Jacquelyn
- Brost Elizabeth
- Brown Jonathan
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruneliere Renaud
- Brunet Sylvie
- Bruni Alessia
- Bruni Graziano
- Bruschi Marco
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
- Bucci Francesca
- Buchholz Peter
- Buckley Andrew
- Buda Stelian Ioan
- Budagov Ioulian
- Buehrer Felix
- Bugge Lars
- Bugge Magnar Kopangen
- Bulekov Oleg
- Bundock Aaron Colin
- Burdin Sergey
- Burghgrave Blake
- Burke Stephen
- Burmeister Ingo
- Busato Emmanuel
- Bussey Peter
- Buszello Claus-Peter
- Butler Bart
- Butler John
- Butt Aatif Imtiaz
- Buttar Craig
- Butterworth Jonathan
- Butti Pierfrancesco
- Buttinger William
- Buzatu Adrian
- Byszewski Marcin
- Büscher Daniel
- Büscher Volker
- Cabrera Urbán Susana
- Caforio Davide
- Cakir Orhan
- Calafiura Paolo
- Calandri Alessandro
- Calderini Giovanni
- Calfayan Philippe
- Calkins Robert
- Caloba Luiz
- Calvet David
- Calvet Samuel
- Camacho Toro Reina
- Camarda Stefano
- Cameron David
- Caminada Lea Michaela
- Caminal Armadans Roger
- Campana Simone
- Campanelli Mario
- Campoverde Angel
- Canale Vincenzo
- Canepa Anadi
- Cano Bret Marc
- Cantero Josu
- Cantrill Robert
- Cao Tingting
- Capeans Garrido Maria Del Mar
- Caprini Irinel
- Caprini Mihai
- Capua Marcella
- Caputo Regina
- Cardarelli Roberto
- Carli Tancredi
- Carlino Gianpaolo
- Carminati Leonardo
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German D
- Carter Janet
- Casadei Diego
- Casado Maria Pilar
- Casolino Mirkoantonio
- Castaneda-Miranda Elizabeth
- Castelli Angelantonio
- Castillo Gimenez Victoria
- Castro Nuno Filipe
- Catastini Pierluigi
- Catinaccio Andrea
- Catmore James
- Cattai Ariella
- Cattani Giordano
- Caudron Julien
- Cavaliere Viviana
- Cavalli Donatella
- Cavalli-Sforza Matteo
- Cavasinni Vincenzo
- Ceradini Filippo
- Cerio Benjamin
- Cerny Karel
- Cerqueira Augusto Santiago
- Cerri Alessandro
- Cerrito Lucio
- Cerutti Fabio
- Cerv Matevz
- Cervelli Alberto
- Cetin Serkant Ali
- Chafaq Aziz
- Chakraborty Dhiman
- Chalupkova Ina
- Chang Philip
- Chapleau Bertrand
- Chapman John Derek
- Charfeddine Driss
- Charlton Dave
- Chau Chav Chhiv
- Chavez Barajas Carlos Alberto
- Cheatham Susan
- Chegwidden Andrew
- Chekanov Sergei
- Chekulaev Sergey
- Chelkov Gueorgui
- Chelstowska Magda Anna
- Chen Chunhui
- Chen Hucheng
- Chen Karen
- Chen Liming
- Chen Shenjian
- Chen Xin
- Chen Ye
- Cheng Hok Chuen
- Cheng Yangyang
- Cheplakov Alexander
- Cherkaoui El Moursli Rajaa
- Cheu Elliott
- Chevalier Laurent
- Chiarella Vitaliano
- Chiefari Giovanni
- Childers John Taylor
- Chilingarov Alexandre
- Chiodini Gabriele
- Chisholm Andrew
- Chislett Rebecca Thalatta
- Chitan Adrian
- Chizhov Mihail
- Chouridou Sofia
- Chow Bonnie Kar Bo
- Chudoba Jiri
- Chwastowski Janusz
- Chytka Ladislav
- Ciftci Abbas Kenan
- Ciftci Rena
- Cinca Diane
- Cindro Vladimir
- Ciocio Alessandra
- Citron Zvi Hirsh
- Ciubancan Mihai
- Clark Allan G
- Clark Philip James
- Clarke Robert
- Clemens Jean-Claude
- Clement Christophe
- Coadou Yann
- Cobal Marina
- Coccaro Andrea
- Cochran James H
- Coffey Laurel
- Cogan Joshua Godfrey
- Cole Brian
- Cole Stephen
- Colijn Auke-Pieter
- Collot Johann
- Colombo Tommaso
- Compostella Gabriele
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon Henry
- Connelly Ian
- Consonni Sofia Maria
- Consorti Valerio
- Constantinescu Serban
- Conti Geraldine
- Conventi Francesco
- Cooke Mark
- Cooper Ben
- Cooper-Sarkar Amanda
- Cooper-Smith Neil
- Copic Katherine
- Cornelissen Thijs
- Corradi Massimo
- Corriveau Francois
- Cortes-Gonzalez Arely
- Cortiana Giorgio
- Costa Giuseppe
- Costa María José
- Costanzo Davide
- Cottin Giovanna
- Cowan Glen
- Cox Brian
- Cranmer Kyle
- Cree Graham
- Crescioli Francesco
- Cribbs Wayne Allen
- Crispin Ortuzar Mireia
- Cristinziani Markus
- Croft Vince
- Crosetti Giovanni
- Crépé-Renaudin Sabine
- Cuciuc Constantin-Mihai
- Cuhadar Donszelmann Tulay
- Cummings Jane
- Curatolo Maria
- Cuthbert Cameron
- Czirr Hendrik
- Czodrowski Patrick
- Côté David
- D'Auria Saverio
- D'Onofrio Monica
- Da Cunha Sargedas De Sousa Mario Jose
- Da Via Cinzia
- Dabrowski Wladyslaw
- Dafinca Alexandru
- Dai Tiesheng
- Dale Orjan
- Dallaire Frederick
- Dallapiccola Carlo
- Dam Mogens
- Daniells Andrew Christopher
- Dano Hoffmann Maria
- Dao Valerio
- Darbo Giovanni
- Darmora Smita
- Dassoulas James
- Dattagupta Aparajita
- Davey Will
- David Claire
- Davidek Tomas
- Davies Eleanor
- Davies Merlin
- Davignon Olivier
- Davison Adam
- Davison Peter
- Davygora Yuriy
- Dawe Edmund
- Dawson Ian
- Daya-Ishmukhametova Rozmin
- de Asmundis Riccardo
- De Castro Stefano
- De Cecco Sandro
- De Groot Nicolo
- de Jong Paul
- De la Torre Hector
- De Lorenzi Francesco
- De Nooij Lucie
- De Pedis Daniele
- De Salvo Alessandro
- De Sanctis Umberto
- De Santo Antonella
- De Vivie De Regie Jean-Baptiste
- De Kaushik
- Dearnaley William James
- Debbe Ramiro
- Debenedetti Chiara
- Dechenaux Benjamin
- Dedovich Dmitri
- Deigaard Ingrid
- Del Peso Jose
- Deliot Frederic
- Delitzsch Chris Malena
- Deliyergiyev Maksym
- Dell'Acqua Andrea
- Dell'Asta Lidia
- Dell'Orso Mauro
- Della Pietra Massimo
- della Volpe Domenico
- Delmastro Marco
- Delsart Pierre-Antoine
- Deluca Carolina
- Demers Sarah
- Demichev Mikhail
- Demilly Aurelien
- Denisov Sergey
- Derendarz Dominik
- Derkaoui Jamal Eddine
- Derue Frederic
- Dervan Paul
- Desch Klaus Kurt
- Deterre Cecile
- Deviveiros Pier-Olivier
- Dewhurst Alastair
- Dhaliwal Saminder
- Di Ciaccio Anna
- Di Ciaccio Lucia
- Di Domenico Antonio
- Di Donato Camilla
- Di Girolamo Alessandro
- Di Girolamo Beniamino
- Di Mattia Alessandro
- Di Micco Biagio
- Di Nardo Roberto
- Di Simone Andrea
- Di Sipio Riccardo
- Di Valentino David
- Dias Flavia
- Diaz Marco Aurelio
- Diehl Edward
- Dietrich Janet
- Dietzsch Thorsten
- Diglio Sara
- Dimitrievska Aleksandra
- Dingfelder Jochen
- Dita Petre
- Dita Sanda
- Dittus Fridolin
- Djama Fares
- Djobava Tamar
- do Vale Maria Aline Barros
- Dobos Daniel
- Doglioni Caterina
- Doherty Tom
- Dohmae Takeshi
- Dolejsi Jiri
- Dolezal Zdenek
- Donadelli Marisilvia
- Donati Simone
- Dondero Paolo
- Donini Julien
- Dopke Jens
- Doria Alessandra
- Dova Maria-Teresa
- Doyle Tony
- Dris Manolis
- Dubbert Jörg
- Dube Sourabh
- Dubreuil Emmanuelle
- Duchovni Ehud
- Duckeck Guenter
- Ducu Otilia Anamaria
- Duda Dominik
- Dudarev Alexey
- Dudziak Fanny
- Duflot Laurent
- Duguid Liam
- Dunford Monica
- Duran Yildiz Hatice
- Durglishvili Archil
- Dwuznik Michal
- Dyndal Mateusz
- Dührssen Michael
- Düren Michael
- Ebke Johannes
- Edson William
- Edwards Nicholas Charles
- Ehrenfeld Wolfgang
- Eifert Till
- Eigen Gerald
- Einsweiler Kevin
- Ekelof Tord
- El Kacimi Mohamed
- Ellert Mattias
- Elles Sabine
- Ellinghaus Frank
- Ellis Nicolas
- Elmsheuser Johannes
- Elsing Markus
- Emeliyanov Dmitry
- Enari Yuji
- Endner Oliver Chris
- Endo Masaki
- Erdmann Johannes
- Ereditato Antonio
- Ernis Gunar
- Ernst Jesse
- Ernst Michael
- Ernwein Jean
- Errede Deborah
- Errede Steven
- Ertel Eugen
- Escalier Marc
- Esch Hendrik
- Escobar Carlos
- Esposito Bellisario
- Etienvre Anne-Isabelle
- Etzion Erez
- Evans Hal
- Ezhilov Alexey
- Fabbri Laura
- Facini Gabriel
- Fakhrutdinov Rinat
- Falciano Speranza
- Falla Rebecca Jane
- Faltova Jana
- Fang Yaquan
- Fanti Marcello
- Farbin Amir
- Farilla Addolorata
- Farooque Trisha
- Farrell Steven
- Farrington Sinead
- Farthouat Philippe
- Fassi Farida
- Fassnacht Patrick
- Fassouliotis Dimitrios
- Favareto Andrea
- Fayard Louis
- Federic Pavol
- Fedin Oleg
- Fedorko Wojciech
- Feigl Simon
- Feligioni Lorenzo
- Feng Cunfeng
- Feng Eric
- Feng Haolu
- Fenyuk Alexander
- Fernandez Perez Sonia
- Ferrag Samir
- Ferrando James
- Ferrari Arnaud
- Ferrari Pamela
- Ferrari Roberto
- Ferreira de Lima Danilo Enoque
- Ferrer Antonio
- Ferrere Didier
- Ferretti Claudio
- Ferretto Parodi Andrea
- Fiascaris Maria
- Fiedler Frank
- Filipuzzi Marco
- Filipčič Andrej
- Filthaut Frank
- Fincke-Keeler Margret
- Finelli Kevin Daniel
- Fiolhais Miguel
- Fiorini Luca
- Firan Ana
- Fischer Adam
- Fischer Julia
- Fisher Wade Cameron
- Fitzgerald Eric Andrew
- Flechl Martin
- Fleck Ivor
- Fleischmann Philipp
- Fleischmann Sebastian
- Fletcher Gareth Thomas
- Fletcher Gregory
- Flick Tobias
- Floderus Anders
- Flores Castillo Luis
- Flowerdew Michael
- Formica Andrea
- Forti Alessandra
- Fortin Dominique
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- Fracchia Silvia
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- Franchino Silvia
- Francis David
- Franconi Laura
- Franklin Melissa
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- Friedrich Conrad
- Friedrich Felix
- Froidevaux Daniel
- Frost James
- Fukunaga Chikara
- Fullana Torregrosa Esteban
- Fulsom Bryan Gregory
- Fuster Juan
- Gabaldon Carolina
- Gabizon Ofir
- Gabrielli Alessandro
- Gabrielli Andrea
- Gadatsch Stefan
- Gadomski Szymon
- Gagliardi Guido
- Gagnon Pauline
- Galea Cristina
- Galhardo Bruno
- Gallas Elizabeth
- Gallop Bruce
- Gallus Petr
- Galster Gorm Aske Gram Krohn
- Gan KK
- Gao Jun
- Gao Yongsheng
- Garay Walls Francisca
- Garberson Ford
- Garcia-Sciveres Maurice
- García Navarro José Enrique
- García Carmen
- Gardner Robert
- Garelli Nicoletta
- Garonne Vincent
- Gatti Claudio
- Gaudio Gabriella
- Gaur Bakul
- Gauthier Lea
- Gavrilenko Igor
- Gay Colin
- Gaycken Goetz
- Gazis Evangelos
- Ge Peng
- Gecse Zoltan
- Gee Norman
- Geerts Daniël Alphonsus Adrianus
- Geich-Gimbel Christoph
- Gemme Claudia
- Gemmell Alistair
- Genest Marie-Hélène
- Gentile Simonetta
- George Matthias
- George Simon
- Gerbaudo Davide
- Gershon Avi
- Ghodbane Nabil
- Giacobbe Benedetto
- Giagu Stefano
- Giangiobbe Vincent
- Giannetti Paola
- Gianotti Fabiola
- Gibson Stephen
- Gillam Thomas
- Gillberg Dag
- Gilles Geoffrey
- Gingrich Douglas
- Giokaris Nikos
- Giordani MarioPaolo
- Giordano Raffaele
- Giorgi Filippo Maria
- Giorgi Francesco Michelangelo
- Giraud Pierre-Francois
- Giugni Danilo
- Giuliani Claudia
- Giulini Maddalena
- Gjelsten Børge Kile
- Gkaitatzis Stamatios
- Gkialas Ioannis
- Gkougkousis Evangelos Leonidas
- Gladilin Leonid
- Glasman Claudia
- Glatzer Julian
- Glaysher Paul
- Glazov Alexandre
- Glonti George
- Goblirsch-Kolb Maximilian
- Goddard Jack Robert
- Godlewski Jan
- Goeringer Christian
- Goldfarb Steven
- Golling Tobias
- Golubkov Dmitry
- Gomes Agostinho
- Gomez Fajardo Luz Stella
- Goncalves Pinto Firmino Da Costa Joao
- Gonella Laura
- Gonzalez Parra Garoe
- Gonzalez-Sevilla Sergio
- González de la Hoz Santiago
- Gonçalo Ricardo
- Goossens Luc
- Gorbounov Petr Andreevich
- Gordon Howard
- Gorelov Igor
- Gorini Benedetto
- Gorini Edoardo
- Gorišek Andrej
- Gornicki Edward
- Goshaw Alfred
- Gostkin Mikhail Ivanovitch
- Gouighri Mohamed
- Goujdami Driss
- Goulette Marc Phillippe
- Goussiou Anna
- Goy Corinne
- Grabas Herve Marie Xavier
- Graber Lars
- Grabowska-Bold Iwona
- Grafström Per
- Grahn Karl-Johan
- Gramling Johanna
- Gramstad Eirik
- Grancagnolo Sergio
- Grassi Valerio
- Gratchev Vadim
- Gray Heather
- Graziani Enrico
- Grebenyuk Oleg
- Greenwood Zeno Dixon
- Gregersen Kristian
- Gregor Ingrid-Maria
- Grenier Philippe
- Griffiths Justin
- Grillo Alexander
- Grimm Kathryn
- Grinstein Sebastian
- Gris Philippe Luc Yves
- Grishkevich Yaroslav
- Grivaz Jean-Francois
- Grohs Johannes Philipp
- Grohsjean Alexander
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- Yamaguchi Hiroshi
- Yamaguchi Yohei
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- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
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- Yang Yi
- Yanush Serguei
- Yao Liwen
- Yao Weiming
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henry
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yilmaz Metin
- Yoosoofmiya Reza
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christopher John
- Youssef Saul
- Yu David Ren-Hwa
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zaman Aungshuman
- Zambito Stefano
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zevi della Porta Giovanni
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Lei
- Zhou Ning
- Zhu Cheng Guang
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Robert
- Zimmermann Simone
- Zimmermann Stephanie
- Zinonos Zinonas
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zutshi Vishnu
- Zwalinski Lukasz
- Åkesson Torsten Paul Ake
- Åsman Barbro
- Ženiš Tibor
- Publication venue
- Publication date
- 01/01/2014
- Field of study
A search for scalar particles decaying via narrow resonances into two photons in the mass range 65–600 GeV is performed using 20.3fb−1 of s=8TeV pp collision data collected with the ATLAS detector at the Large Hadron Collider. The recently discovered Higgs boson is treated as a background. No significant evidence for an additional signal is observed. The results are presented as limits at the 95% confidence level on the production cross section of a scalar boson times branching ratio into two photons, in a fiducial volume where the reconstruction efficiency is approximately independent of the event topology. The upper limits set extend over a considerably wider mass range than previous searches