Effect of rest time on heart rate, perceived exertion, and strength

Finding a proper work/rest schedule is considered an important factor for improved efficiency, safety, and a higher rate of productivity in the workplace. The purpose of this study was to determine the optimum rest period for lifting tasks using heart rate, perceived exertion, and physical strength. First, the maximum acceptable weight of the box to be lifted was determined for each one of 10 participants using a psychophysical approach. Then on separate days, participants were required to repetitively lift the box from knuckle height to shoulder height for 20 minutes. They were then allowed to rest 5, 10, 15, or 20 minutes. After each rest period, the participants repeated the same lifting task. Before and after each lifting task, measurements for heart rate, perceived exertion (Borg scale), static arm strength, and hand strength were recorded. The relationship between four dependent variables (heart rate, Borg scale value, static arm strength, hand (grip) strength) and two independent variables of the experiment (resting time/phase effect), and the interactions effect was examined by the experimenter, through conducting a statistical analysis (Two-Way Repeated-Measures ANOVA) and pairwise comparison test (Post Hoc test). In addition the trend lines for all dependent variables were investigated as an additional analysis. The recovery percentages of heart rate, along with the statistically significant results of perceived exertion, indicate that 15 minutes of rest is the optimum rest period. The hand strength graph suggests that at least 10 minutes is needed for recovery. The trend for static arm strength did not show any particular correlation or pattern. The overall findings of this study suggest that workers should be provided with 15 minutes of rest to recover from a 20 minute repetitive lifting task

Oxidative Stress and Parkinson's Disease: New Hopes in Treatment with Herbal Antioxidants

Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology. However, exposure to environmental toxins, head trauma, inflammation, and free radicals are potential reasons. Recently, the role of oxidative stress in neurological abnormalities, including PD, has been particularly addressed. Antioxidant remedies, particularly herbal antioxidants, have revealed new perspectives of research and therapy as possible preventive and therapeutic approaches for PD. In this paper, we reviewed the recently published papers on the effects of herbal medicines on PD alongside the pathogenesis of PD with regard to oxidative stress

Normal Exophthalmometry Values in Iranian Population: A Meta-analysis: A complete translation from Farsi

This article is based on a study first reported in Farsi in the Bina Journal of Ophthalmology, titled بررسی مقادیر طبیعی اگزوفتالمومتري در جمعیت ایرانی: مطالعه مرور نظامند و متاآنالیز, Volume 24, Issue 2 (Winter 2019) 2019/05/28. Original URL: https://binajournal.org/article-1-985-fa.pdf There are limited studies on the normal values of eye protrusion in Iran. Systematic efforts to provide acceptable normal exophthalmometry values for Iranian population are required for a proper approach to orbital diseases. English and Farsi language publications in PubMed, the ISI Web of Knowledge database, Iranian SID, and Iran Medex were searched using the following keywords: “proptosis”, “eye protrusion”, “exophthalmous”, “Hertel exophthalmometer” and “Iran”. Four articles from 1995 to 2010 were found and included in the meta-analysis. Statistical analysis was performed using the Metan command within Stata 15.0 software. It included 3,696 subjects in whom the average eye protrusion was 16.5 mm (95% CI: 15.1–17.8) in men and 16.2 mm (95% CI: 14.6–17.7) in women (P = 0.5). Mean left and right eye protrusion were 16.3 (95% CI: 14.7–18.1) and 16.4 mm (95% CI: 14.8–17.7), (P = 0.3), respectively. While Iranian teenagers (13–19 years old) showed a mean value of 17.1 mm (95% CI: 15.0–19.1), older age group (≥20 years) showed a lower mean eye protrusion of 16.3 mm (95% CI: 14.8–17.7). Considering the two standard deviations, the highest normal value of eye protrusion in Iranian population is 20.1 mm. In conclusion, Iranian normal eye protrusion values were higher than Asians and lower than Caucasians

Return Volatility and Asymmetric News of Computer Industry stocks in Tehran Stock Exchange (TEX)

According to leverage and volatility feedback effects there are relationships between the return and the risk of stocks in the stock markets. Using daily and weekly data of Computer industry index in Tehran stock Exchange (TEX), this study investigates both leverage and volatility feedback effects applying GARCH family models and Full Information Maximum Likelihood (FIML) estimation method, during 01/2007- 10/2013 period. According to GARCH-M model estimations the first hypothesis of the research (Return volatility of computer industry in TEX affects the return significantly) cannot be rejected for daily data during 02/2010 to 10/2013 (the 2nd period) which both return and return volatility were much more volatile rather than 01/2007 - 02/2010 (the 1st period), but this hypothesis can be rejected for daily data in the 1st period and weekly data in both periods. According to EGARCH and TGARCH estimations the second main hypothesis of the research (a negative return makes return volatility of computer industry in TEX more volatile) cannot be rejected for both daily and weekly data in the 1st period, but can be rejected for both data during the 2nd period

Identification of medicinal plants effective on sinusitis native to Shiraz province in Iran

Sinusitis is one of the most infectious diseases that affect holes around the nose such as frontal ethmoid sinuses, maxillary and sphenoid. Symptoms usually include nasal congestion and obstruction, feeling of pressure or fullness in the face, anterior or posterior nasal causing discharge, headaches, fever, swelling and erythema in forehead or cheek and cough. The symptoms might be edema and mucosal congestion, nasal drainage, posterior nasal discharge, nasal septum deviation and polyps. The medicinal plants identified for instance are Amygdalus scoparia Spach, Echinophora platyloba DC., Haplophyllum perforatum L, Lavandula stoechas L, Borago officinalis, Matricaria recutita, Descurainia Sophia (L.) Schr and Haplophyllum perforatum L to treat sinusitis in Shiraz. Many of these plants have antioxidant activity and contain bioactive compounds such as flavonoids, flavonoids, polyphenols, anthocyanins, tannins and many other pharmaceutical bioactive ingredients that have effects on sinusitis. This paper aims to review the recently published papers in this topic

Medication use in uncontrolled pediatric asthma:Results from the SysPharmPediA study

Background: Uncontrolled pediatric asthma has a large impact on patients and their caregivers. More insight into determinants of uncontrolled asthma is needed. We aim to compare treatment regimens, inhaler techniques, medication adherence and other characteristics of children with controlled and uncontrolled asthma in the: Systems Pharmacology approach to uncontrolled Paediatric Asthma (SysPharmPediA) study. Material and methods: 145 children with moderate to severe doctor-diagnosed asthma (91 uncontrolled and 54 controlled) aged 6–17 years were enrolled in this multicountry, (Germany, Slovenia, Spain, and the Netherlands) observational, case-control study. The definition of uncontrolled asthma was based on asthma symptoms and/or exacerbations in the past year. Patient-reported adherence and clinician-reported medication use were assessed, as well as lung function and inhalation technique. A logistic regression model was fitted to assess determinants of uncontrolled pediatric asthma. Results: Children in higher asthma treatment steps had a higher risk of uncontrolled asthma (OR (95%CI): 3.30 (1.56–7.19)). The risk of uncontrolled asthma was associated with a larger change in FEV1% predicted post and pre-salbutamol (OR (95%CI): 1.08 (1.02–1.15)). Adherence and inhaler techniques were not associated with risk of uncontrolled asthma in this population. Conclusion: This study showed that children with uncontrolled moderate-to-severe asthma were treated in higher treatment steps compared to their controlled peers, but still showed a higher reversibility response to salbutamol. Self-reported adherence and inhaler technique scores did not differ between controlled and uncontrolled asthmatic children. Other determinants, such as environmental factors and differences in biological profiles, may influence the risk of uncontrolled asthma in this moderate to severe asthmatic population

The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

Abstract: Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible three-dimensional molecular and cellular atlas of the human body, in health and under various disease conditions

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Financial Development, International Trade and Economic Growth: Empirical Evidence from Pakistan

The study utilizes the Autoregressive-distributed lag (ARDL) approach for cointegration and Granger causality test, to explore the long run equilibrium relationship and the possible direction of causality between international trade, financial development and economic growth for the Pakistan economy. Imports plus exports of goods and services is used as a proxy for international trade, while broad money (M2) and gross domestic product (GDP) are used as the proxies for financial development and economic growth, respectively. Result explores a long run relationship between the variables. In case of Pakistan, economy supply leading hypothesis is accepted. Moreover, unidirectional causality is observed from international trade to economic growth and from financial development to international trade