157 research outputs found
Disease Severity in Patients Infected with Leishmania mexicana Relates to IL-1β
- Author
- A Nemetz
- A Olivo-Díaz
- A Weber
- AB Guimarães-Costa
- AJ Frodsham
- AM Duque
- B Woolf
- C Pirmez
- CA Dinarello
- Claudia Rangel-Escareño
- DR Faria
- E Garza González
- E Vairaktaris
- E Voronov
- Edith A. Fernández-Figueroa
- FL van den Veerdonk
- G Carrada
- Georgina Carrada-Figueroa
- GI Matos
- I Becker
- Ingeborg Becker
- J Hernández-Ruíz
- J Ji
- J Zabaleta
- JM Kang
- K Brajao
- K Kautz
- K Ley
- Karol Carrillo-Sánchez
- KS Lopez
- LS Miller
- M Whyte
- MA Hidalgo
- MI Villaseñor
- MJ Teixeira
- NC Peters
- Norma Salaiza-Suazo
- PD Sasieni
- RC Read
- Rodrigo Correa-Oliveira
- S Benko
- S Sriskandan
- Santiago March-Mifsut
- SE Kamali
- SS Erbek
- T Laskay
- U Meyer-Hoffert
- V Boaventura
- V Pétrilli
- Valeria Espinosa-Mateos
- Publication venue
- Public Library of Science
- Publication date
- 22/05/2012
- Field of study
Leishmania mexicana can cause both localized (LCL) and diffuse (DCL) cutaneous leishmaniasis, yet little is known about factors regulating disease severity in these patients. We analyzed if the disease was associated with single nucleotide polymorphisms (SNPs) in IL-1β (−511), CXCL8 (−251) and/or the inhibitor IL-1RA (+2018) in 58 Mexican mestizo patients with LCL, 6 with DCL and 123 control cases. Additionally, we analyzed the in vitro production of IL-1β by monocytes, the expression of this cytokine in sera of these patients, as well as the tissue distribution of IL-1β and the number of parasites in lesions of LCL and DCL patients. Our results show a significant difference in the distribution of IL-1β (−511 C/T) genotypes between patients and controls (heterozygous OR), with respect to the reference group CC, which was estimated with a value of 3.23, 95% CI = (1.2, 8.7) and p-value = 0.0167), indicating that IL-1β (−511 C/T) represents a variable influencing the risk to develop the disease in patients infected with Leishmania mexicana. Additionally, an increased in vitro production of IL-1β by monocytes and an increased serum expression of the cytokine correlated with the severity of the disease, since it was significantly higher in DCL patients heavily infected with Leishmania mexicana. The distribution of IL-1β in lesions also varied according to the number of parasites harbored in the tissues: in heavily infected LCL patients and in all DCL patients, the cytokine was scattered diffusely throughout the lesion. In contrast, in LCL patients with lower numbers of parasites in the lesions, IL-1β was confined to the cells. These data suggest that IL-1β possibly is a key player determining the severity of the disease in DCL patients. The analysis of polymorphisms in CXCL8 and IL-1RA showed no differences between patients with different disease severities or between patients and controls
Natural History of MYH7-Related Dilated Cardiomyopathy
- Author
- Acereda TP
- Alvarez-Rubio J
- Antoniutti G
- Baas A
- Barriales-Villa R
- Bermejo J
- Bermúdez-Jiménez FJ
- Bilinska Z
- Billon C
- Bjerre JV
- Brunner HG
- Cabrera-Romero E
- Caimi-Martinez F
- Calvo M
- Campuzano O
- Cannie D
- Cesar S
- Chmielewski P
- Cobo-Marcos M
- Corada BA
- Coto E
- Cremer-Luengos D
- de Frutos F
- Domínguez F
- Dooijes D
- Díaz-Expósito A
- Díez-Aja López SL
- Díez-López C
- Elliot PM
- Escobar-Lopez L
- Espinosa MA
- Fatkin D
- Favilli S
- Fernández de Bobadilla ÁC
- Fernández AI
- Fuentes-Cañamero ME
- Gallego-Delgado M
- Garcia-Pavia P
- García-Granja PE
- García-Pinilla JM
- García-Álvarez A
- García-Álvarez MI
- Gaztañaga-Arantzamendi L
- Gimeno-Blanes JR
- Girolami F
- González-López E
- Gutiérrez RF
- Gutiérrez-García L
- Gómez C
- Gómez J
- Haas J
- Hansen FG
- Heymans SRB
- Jansen M
- Jiménez-Jáimez J
- Jiménez-Rubio C
- Johnson R
- Krebsova A
- Kubanek M
- Limeres J
- Lopes LR
- Lopez-Sainz A
- Lorca R
- López Ledesma B
- López-Díaz J
- Macías R
- Meder B
- Mogensen J
- Méndez I
- Navarro-Peñalver M
- Negreira-Caamaño M
- Ochoa JP
- Onaindia-Gandarias JJ
- Palomino-Doza J
- Payá VC
- Perez-Perez AJ
- Peña-Peña ML
- Piqueras-Flores J
- Ploski R
- Pérez-Cabeza AI
- Rasmussen TB
- Rekondo-Olaetxea J
- Restrepo-Córdoba MA
- Ripoll-Vera T
- Robles-Mezcua A
- Roche Fortea I
- Rodríguez Reguero JJ
- Rodríguez-Palomares JF
- Rodríguez-Sánchez I
- Ruiz-Guerrero L
- Sabater-Molina M
- Sarquella-Brugada G
- Syrris P
- Truszkowska G
- Verdonschot JAJ
- Vilches S
- Villacorta E
- Wahbi K
- Zamarreño-Golvano E
- Zorio E
- Publication venue
- 'Elsevier BV'
- Publication date
- 11/10/2022
- Field of study
BACKGROUND: Variants in myosin heavy chain 7 (MYH7) are responsible for disease in 1% to 5% of patients with dilated cardiomyopathy (DCM); however, the clinical characteristics and natural history of MYH7-related DCM are poorly described. OBJECTIVE: We sought to determine the phenotype and prognosis of MYH7-related DCM. We also evaluated the influence of variant location on phenotypic expression. METHODS: We studied clinical data from 147 individuals with DCM-causing MYH7 variants (47.6% female; 35.6 ± 19.2 years) recruited from 29 international centers. RESULTS: At initial evaluation, 106 (72.1%) patients had DCM (left ventricular ejection fraction: 34.5% ± 11.7%). Median follow-up was 4.5 years (IQR: 1.7-8.0 years), and 23.7% of carriers who were initially phenotype-negative developed DCM. Phenotypic expression by 40 and 60 years was 46% and 88%, respectively, with 18 patients (16%) first diagnosed at <18 years of age. Thirty-six percent of patients with DCM met imaging criteria for LV noncompaction. During follow-up, 28% showed left ventricular reverse remodeling. Incidence of adverse cardiac events among patients with DCM at 5 years was 11.6%, with 5 (4.6%) deaths caused by end-stage heart failure (ESHF) and 5 patients (4.6%) requiring heart transplantation. The major ventricular arrhythmia rate was low (1.0% and 2.1% at 5 years in patients with DCM and in those with LVEF of ≤35%, respectively). ESHF and major ventricular arrhythmia were significantly lower compared with LMNA-related DCM and similar to DCM caused by TTN truncating variants. CONCLUSIONS: MYH7-related DCM is characterized by early age of onset, high phenotypic expression, low left ventricular reverse remodeling, and frequent progression to ESHF. Heart failure complications predominate over ventricular arrhythmias, which are rare
Identification of sixteen novel candidate genes for late onset Parkinson’s disease
- Author
- Acampora D
- Adarmes-Gómez AD
- Aguilar M
- Aitkulova A
- Akhmetzhanov V
- Alcalay RN
- Alvarez I
- Alvarez V
- Bandres-Ciga S
- Barrero FJ
- Bernal-Bernal I
- Billingsley K
- Blauwendraat C
- Blazquez M
- Bonilla-Toribio M
- Botía JA
- Boungiorno MT
- Bras J
- Brice A
- Brockmann K
- Bubb V
- Buiza-Rueda D
- Carrillo F
- Carrión-Claro M
- Cerdan D
- Chelban V
- Ciullo M
- Clarimón J
- Clarke C
- Compta Y
- Cookson MR
- Corvol J-C
- Craig DW
- Danjou F
- de Munain Arregui AL
- Di Giovannantonio LG
- Diez-Fairen M
- Dols-Icardo O
- Duarte J
- Duran R
- D’Esposito M
- Errazquin FP
- Escamilla-Sevilla F
- Escott-Price V
- Esposito T
- Ezquerra M
- Faghri F
- Feliz C
- Fernández M
- Fernández-Santiago R
- Finkbeiner S
- Foltynie T
- Gambardella S
- Gan-Or Z
- Garcia C
- García-Ruiz P
- Gasser T
- Gialluisi A
- Gianfrancesco F
- Gibbs JR
- Gonzalez-Aramburu I
- González MM
- Guelfi S
- Guerreiro R
- Gómez-Garre P
- Hardy J
- Hassin-Baer S
- Heredia MJG
- Hernandez DG
- Heutink P
- Hoenicka J
- Holmans P
- Houlden H
- Iacoviello L
- Infante J
- Iwaki H
- Jesús S
- Jimenez-Escrig A
- Kaishybayeva G
- Kaiyrzhanov R
- Kaiyrzhanov R
- Karimova A
- Kia DA
- Kinghorn KJ
- Koks S
- Krohn L
- Krohn L
- Kulisevsky J
- Labrador-Espinosa MA
- Leonard HL
- Lesage S
- Lewis P
- Lombardi A
- Lopez-Sendon JL
- Lovering R
- Lubbe S
- Lungu C
- Macias D
- Majamaa K
- Manzoni C
- Marinus J
- Marti MJ
- Martinez M
- Martínez-Castrillo JC
- Marín J
- Mata M
- Mencacci NE
- Middlehurst B
- Mir P
- Modugno N
- Mok KY
- Morris HR
- Morrison KE
- Muñoz E
- Méndez-del-Barrio C
- Mínguez A
- Nalls MA
- Narendra D
- Noyce AJ
- Nutile T
- Ojo OO
- Okubadejo NU
- Pagola AG
- Pagonabarraga J
- Pastor P
- Periñán-Tocino T
- Pietracupa S
- Pihlstrom L
- Plun-Favreau H
- Quinn J
- Reccia MG
- Reed X
- Rezola EM
- Rizig M
- Rizzu P
- Robak L
- Rodriguez AS
- Rouleau GA
- Ruggiero D
- Ruiz-Martínez J
- Ruz C
- Ryten M
- R’Bibo L
- Sadykova D
- Scala S
- Scholz SW
- Schreglmann S
- Schulte C
- Sharma M
- Shashkin C
- Shulman JM
- Sierra M
- Siitonen A
- Simeone A
- Simón-Sánchez J
- Singleton AB
- Suarez-Sanmartin E
- Taba P
- Tabernero C
- Tan M
- Tartari JP
- Tejera-Parrado C
- Toft M
- Tolosa E
- Torres IM
- Trabzuni D
- Valldeoriola F
- van Hilten JJ
- Van Keuren-Jensen K
- Vargas-González L
- Vela L
- Vives F
- Williams N
- Wood NW
- Yarza JAB
- Zharkynbekova N
- Zharmukhanov Z
- Zholdybayeva E
- Zimprich A
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 21/06/2021
- Field of study
Background
Parkinson’s disease (PD) is a neurodegenerative movement disorder affecting 1–5% of the general population for which neither effective cure nor early diagnostic tools are available that could tackle the pathology in the early phase. Here we report a multi-stage procedure to identify candidate genes likely involved in the etiopathogenesis of PD.
Methods
The study includes a discovery stage based on the analysis of whole exome data from 26 dominant late onset PD families, a validation analysis performed on 1542 independent PD patients and 706 controls from different cohorts and the assessment of polygenic variants load in the Italian cohort (394 unrelated patients and 203 controls).
Results
Family-based approach identified 28 disrupting variants in 26 candidate genes for PD including PARK2, PINK1, DJ-1(PARK7), LRRK2, HTRA2, FBXO7, EIF4G1, DNAJC6, DNAJC13, SNCAIP, AIMP2, CHMP1A, GIPC1, HMOX2, HSPA8, IMMT, KIF21B, KIF24, MAN2C1, RHOT2, SLC25A39, SPTBN1, TMEM175, TOMM22, TVP23A and ZSCAN21. Sixteen of them have not been associated to PD before, were expressed in mesencephalon and were involved in pathways potentially deregulated in PD. Mutation analysis in independent cohorts disclosed a significant excess of highly deleterious variants in cases (p = 0.0001), supporting their role in PD.
Moreover, we demonstrated that the co-inheritance of multiple rare variants (≥ 2) in the 26 genes may predict PD occurrence in about 20% of patients, both familial and sporadic cases, with high specificity (> 93%; p = 4.4 × 10− 5). Moreover, our data highlight the fact that the genetic landmarks of late onset PD does not systematically differ between sporadic and familial forms, especially in the case of small nuclear families and underline the importance of rare variants in the genetics of sporadic PD.
Furthermore, patients carrying multiple rare variants showed higher risk of manifesting dyskinesia induced by levodopa treatment.
Conclusions
Besides confirming the extreme genetic heterogeneity of PD, these data provide novel insights into the genetic of the disease and may be relevant for its prediction, diagnosis and treatment
QCD and strongly coupled gauge theories : challenges and perspectives
- Author
- A Accardi
- A Accardi
- A Accardi
- A Adams
- A Afanasev
- A Alexandru
- A Alexandru
- A Alexandru
- A Ali
- A Ali
- A Ali
- A Amato
- A Andronic
- A Andronic
- A Anisimov
- A Antognini
- A Antognini
- A Arvanitaki
- A Azatov
- A Banfi
- A Banfi
- A Barranco
- A Bazavov
- A Bazavov
- A Bazavov
- A Bazavov
- A Beraudo
- A Browman
- A Buzzatti
- A Bzdak
- A Bzdak
- A Calle-Cordon
- A Celis
- A Cheng
- A Chodos
- A Crivellin
- A Cucchieri
- A Czarnecki
- A Czarnecki
- A Denner
- A Deuzeman
- A Deuzeman
- A Deuzeman
- A Dobado
- A Donnachie
- A Donos
- A DotΘ
- A Drukier
- A Dumitru
- A Dumitru
- A Dumitru
- A Esposito
- A Forster
- A Francis
- A Freitas
- A Gal
- A Gouvea de
- A Gray
- A Grimbach
- A Gynther
- A Hameren van
- A Hameren van
- A Hasenfratz
- A Hoang
- A Hoang
- A H÷cker
- A Idilbi
- A Idilbi
- A Khodjamirian
- A Kisiel
- A Knecht
- A Knecht
- A Kovner
- A Kryjevski
- A Kulesza
- A Kurkela
- A Kurkela
- A Kurkela
- A Lenz
- A Li
- A Maas
- A Maas
- A Majumder
- A Majumder
- A Majumder
- A Menon
- A Mocsy
- A Mocsy
- A Morsch
- A Nyffeler
- A Orgogozo
- A Orgogozo
- A Ortiz
- A Patella
- A Paul
- A Pich
- A Pich
- A Pich
- A Pich
- A Pich
- A Pichlmaier
- A Pineda
- A Pineda
- A Pineda
- A Pineda
- A Pineda
- A Pineda
- A Pineda
- A Ramos
- A Ramos
- A Roeck De
- A Rothkopf
- A Salvio
- A Schmitt
- A Schmitt
- A Schmitt
- A Schmitt
- A Schmitt
- A Schmitt
- A Schwenk
- A Serebrov
- A Sibirtsev
- A Sternbeck
- A Thiel
- A Toia
- A Vairo
- A Vairo
- A Vuorinen
- A. Kalweit
- A. Mischke
- A. Pich
- A. S. Kronfeld
- A. Schmitt
- A. Vairo
- A. Vuorinen
- AA Andrianov
- AA Andrianov
- AA Khan
- AA Penin
- AA Penin
- AA Penin
- AA Petrov
- AB Balantekin
- AB Balantekin
- AB Larionov
- AB Zamolodchikov
- AC Aguilar
- AC Cordon
- AD Martin
- AD Martin
- AD Martin
- AE Bondar
- AE Nelson
- AE Snyder
- AH Mueller
- AH Mueller
- AJ Baltz
- AJ Buras
- AJ Buras
- AJ Buras
- AJ Buras
- AJ Buras
- AJ Buras
- AJ Buras
- AK Leibovich
- AL Fitzpatrick
- AL Fitzpatrick
- AM Bernstein
- AM Clogston
- AM Polyakov
- AM Polyakov
- AM Polyakov
- AM Poskanzer
- AP Bakulev
- AP Bakulev
- AP Bakulev
- AP Bakulev
- AP Serebrov
- AP Szczepaniak
- AR Zhitnitsky
- AS Arapoglu
- AS Gorsky
- AS Kronfeld
- AS Kronfeld
- AS Kronfeld
- AS Kronfeld
- AS Schwarz
- AT Davies
- AT Yue
- AV Anisovich
- AV Anisovich
- AV Anisovich
- AV Anisovich
- AV Anisovich
- AV Anisovich
- AV Belitsky
- AV Belitsky
- AV Belitsky
- AV Belitsky
- AV Efremov
- AV Kovalenko
- AV Kovalenko
- AV Manohar
- AV Manohar
- AV Manohar
- AV Manohar
- AV Radyushkin
- AV Radyushkin
- AV Radyushkin
- AV Radyushkin
- AV Smirnov
- AW Steiner
- AX El-Khadra
- AY Alekseev
- B Adeva
- B Adeva
- B Alver
- B Ananthanarayan
- B Batell
- B Bellazzini
- B Berdnikov
- B Bhattacharya
- B Bhattacharya
- B Blossier
- B Blossier
- B Dehnadi
- B Frois
- B Gong
- B Gong
- B Gong
- B Gong
- B Gong
- B Gong
- B Grzadkowski
- B Haskell
- B Haskell
- B Holdom
- B Holdom
- B Kubis
- B Lucini
- B Melić
- B Moussallam
- B Müller
- B Müller
- B MΣrkisch
- B Page
- B Pendleton
- B Pire
- B Plaster
- B Povh
- B Schenke
- B Schrempp
- B Sheikholeslami
- B Wu
- B. Ketzer
- BA Brown
- BA Burrington
- BA Dobrescu
- BA Kniehl
- BA Kniehl
- BA Thacker
- BB Back
- BB Brandt
- BC Regan
- BC Rislow
- BE Lautrup
- BG Zakharov
- BG Zakharov
- BJ Menadue
- BJ Owen
- BM Roberts
- BO Lange
- BR Holstein
- BS Chandrasekhar
- BU Musch
- C Alexandrou
- C Alexandrou
- C Alexandrou
- C Alexandrou
- C Alexandrou
- C Alexandrou
- C Alexandrou
- C Amsler
- C Anastasiou
- C Anzai
- C Aubin
- C Aubin
- C Aubin
- C Aubin
- C Aubin
- C Bernard
- C Bourrely
- C Csaki
- C Csaki
- C DeTar
- C Ditsche
- C Donato Di
- C Fernández-Ramírez
- C Fernández-Ramírez
- C Fernández-Ramírez
- C Fuchs
- C Gale
- C Gattringer
- C Gattringer
- C Gattringer
- C Gerschel
- C Hartnack
- C Jayalath
- C Lourenτo
- C Manuel
- C McNeile
- C McNeile
- C McNeile
- C Meng
- C Michael
- C Michael
- C Morningstar
- C Nunez
- C Pelissier
- C Rappold
- C Ratti
- C Shen
- C Shen
- C-H Chang
- C-M Chang
- C-Y Chen
- C. A. Salgado
- CA Baker
- CA Baker
- CA Meyer
- CA Salgado
- CB Lang
- CB Lang
- CB Lang
- CB Paranavitane
- CE Carlson
- CE Carlson
- CE Carlson
- CE Wolfe
- CG Boyd
- CG Callan
- CG Parthey
- CJ Bomhof
- CJ Morningstar
- CL Korpa
- CL Schat
- CM Arnesen
- CM Maekawa
- CP Herzog
- CP Herzog
- CR Allton
- CS Fischer
- CS Fischer
- CT Hill
- CT Sachrajda
- CTH Davies
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bernard
- D Arean
- D Babusci
- D Bailin
- D Bak
- D Bandurin
- D Banerjee
- D Becirevic
- D Becirevic
- D Becirevic
- D Bernecker
- D Besak
- D Binosi
- D Binosi
- D Blaschke
- D Blaschke
- D Blaschke
- D Bodeker
- D Bodeker
- D Bodeker
- D Boer
- D Boito
- D Diakonov
- D Diakonov
- D Diakonov
- D Dubbers
- D Dubbers
- D Dudal
- D Elander
- D Espriu
- D Florian de
- D Florian de
- D Florian de
- D Forde
- D Gaiotto
- D Gotta
- D Grumiller
- D Guadagnoli
- D Jido
- D Kang
- D Kharzeev
- D Kharzeev
- D Kharzeev
- D Mateos
- D Melconian
- D Mohler
- D Molnar
- D Müller
- D Ng
- D Page
- D Pirjol
- D Pirjol
- D Pirjol
- D Ruic
- D Sahoo
- D Steineder
- D Steineder
- D Teaney
- D Tong
- D Zwanziger
- D Zwanziger
- D-Y Chen
- D. Keane
- DA Demir
- DB Kaplan
- DB Kaplan
- DB Kaplan
- DB Kaplan
- DB Kaplan
- DB Leinweber
- DB Leinweber
- DC McGlinchey
- DE Kharzeev
- DE Kharzeev
- DE Kharzeev
- DE Morrissey
- DG Yakovlev
- DJ Dean
- DJ Salvat
- DJ Schwarz
- DM Alde
- DM Alde
- DM Asner
- DS Armstrong
- DT Son
- DT Son
- DT Son
- DT Son
- DT Son
- DT Son
- DV Amelin
- DV Shirkov
- DW Sivers
- E Applebaum
- E Botta
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Braaten
- E Conde
- E Dalgic
- E Eichten
- E Eichten
- E Epelbaum
- E Epelbaum
- E Ferreiro
- E Flowers
- E Franco
- E Frodermann
- E Golowich
- E Gregory
- E Gámiz
- E Iancu
- E Kiritsis
- E Kiritsis
- E Klempt
- E Kuflik
- E Laenen
- E Leader
- E Massot
- E Megias
- E Mereghetti
- E Perez
- E Poppitz
- E Rafael de
- E Schnedermann
- E Sezgin
- E Shintani
- E Shintani
- E Shintani
- E Shintani
- E Shuster
- E Witten
- E Witten
- E Witten
- E Witten
- E-M Ilgenfritz
- E. Kiritsis
- E. Pallante
- EB Gregory
- EC Poggio
- ED Skillman
- EE Jenkins
- EE Jenkins
- EE Kolomeitsev
- EG Ferreiro
- EJ Eichten
- EL Berger
- ER Berger
- ES Fraga
- F Antinori
- F Arleo
- F Arleo
- F Arleo
- F Arleo
- F Becattini
- F Berruto
- F Bezrukov
- F Bruckmann
- F Burger
- F Cachazo
- F Caravaglios
- F Cascioli
- F D'Eramo
- F D'Eramo
- F Diberder Le
- F Diberder Le
- F Dominguez
- F Englert
- F Feng
- F Gelis
- F Haas
- F Hautmann
- F Iocco
- F Jegerlehner
- F Jegerlehner
- F Jegerlehner
- F Karsch
- F Karsch
- F Karsch
- F Karsch
- F Lenz
- F Niecknig
- F Osterfeld
- F Preis
- F Preis
- F Steiner
- F Wilczek
- F-K Guo
- F-K Guo
- F-K Guo
- F-K Guo
- F. J. Llanes-Estrada
- FA Berends
- FA Dolan
- FA Dolan
- FE Close
- FE Wietfeldt
- FE Wietfeldt
- FJ Tackmann
- FJM Farley
- FL Shapiro
- FV Gubarev
- G Aarts
- G Aarts
- G Aarts
- G Aarts
- G Agakishiev
- G Altarelli
- G Amoros
- G Bali
- G Bell
- G Bell
- G Bellini
- G Bevilacqua
- G Bevilacqua
- G Bhanot
- G Bozzi
- G Buchalla
- G Buchalla
- G Burdman
- G Burdman
- G Cacciapaglia
- G Cacciapaglia
- G Colangelo
- G Colangelo
- G Colangelo
- G Corcella
- G Cullen
- G Cullen
- G D'Ambrosio
- G D'Ambrosio
- G Degrassi
- G Ecker
- G Ecker
- G Eichmann
- G Eichmann
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- Y-Q Ma
- Y-Q Ma
- Y-Q Ma
- Y-T Chien
- Y-Y Bu
- Y-Y Keum
- YA Karpenko
- YA Simonov
- YL Dokshitzer
- YL Dokshitzer
- YM Antipov
- YM Antipov
- YV Kovchegov
- YV Kovchegov
- YV Kovchegov
- YV Stadnick
- YY Keum
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- Z Fodor
- Z Fu
- Z Fu
- Z Komargodski
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- Z Ligeti
- Z Ligeti
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- Z-B Kang
- Z-B Kang
- Z-G He
- Z-G He
- Z-H Li
- Z-W Lin
- Z-W Lin
- Z. Fodor
- Publication venue
- Publication date
- 01/01/2014
- Field of study
We highlight the progress, current status, and open challenges of QCD-driven physics, in theory and in experiment. We discuss how the strong interaction is intimately connected to a broad sweep of physical problems, in settings ranging from astrophysics and cosmology to strongly coupled, complex systems in particle and condensed-matter physics, as well as to searches for physics beyond the Standard Model. We also discuss how success in describing the strong interaction impacts other fields, and, in turn, how such subjects can impact studies of the strong interaction. In the course of the work we offer a perspective on the many research streams which flow into and out of QCD, as well as a vision for future developments.Peer reviewe
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
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- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
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- Herruzo-Aviles A
- Heunks LM
- Hewitt H
- Heyne T
- Hickey S
- Hidalgo C
- Hikasa Y
- Hillier SD
- Himmel Y
- Himpe D
- Hinojosa-Perez R
- Hirata A
- Hirayama T
- Hirohata S
- Hodgson LE
- Hodgson LE
- Hofmeijer J
- Hollands S
- Hom H
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- Hopkins PA
- Hoppu S
- Hoppu S
- Horkan CM
- Horstmann C
- Horton A
- Horvat A
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- Houzé S
- Houzé S
- Howes D
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- Hrachovina M
- Hraiech S
- Hravnak M
- Hu HC
- Hua Y
- Hualde JB
- Hualde JB
- Hualde JB
- Hualde JB
- Hualde JB
- Hualde JB
- Huang CH
- Huang WC
- Huang WC
- Huang WC
- Huang WC
- Hubbard A
- Huber W
- Huddart S
- Hull AM
- Hung CY
- Hung WT
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- Huot B
- Husheer SL
- Hutchings S
- Hutchison R
- Hwang GS
- Hwang GS
- Ibañes PG
- Ibsen M
- Idei M
- Idei M
- Idone FA
- Iesu E
- Iesu E
- Iglesias-Santiago A
- Ignacio ML
- Iida A
- Iijima H
- Ilan R
- Ilyina V
- Imanaka H
- Inaloo S
- Ince C
- Iotti GA
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- IPREA Study Group
- Irazabal JM
- Irazabal JM
- Ishimatsu S
- Itenov TS
- Iwamoto M
- Izawa M
- Izdes S
- Jaber S
- Jacky A
- Jacobs FM
- Jacques T
- Jaffal K
- Jamali S
- Jang BH
- Janotka M
- Janotka M
- Janotka M
- Jansen D
- Jansen N
- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
- Jardim JJ
- Jardim M
- Jareño A
- Javadpour S
- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
- Jensen AE
- Jensen JU
- Jeon YD
- Jeon YD
- Jeong IY
- Jeong IY
- Jeong WY
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- Jian Z
- Jiao LR
- Jibaja M
- Jimenez-Herrera MF
- Jiménez GJ
- Jo YH
- Joachim J
- Jochmans S
- John G
- Jonas M
- Jonas M
- Jonas M
- Jones C
- Joshi R
- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
- Judickas S
- Juez A
- Juliarena A
- Jun IG
- Jun IG
- Jung K
- Jung KW
- Junior JM
- Kaczirek K
- Kaese S
- Kalani N
- Kalenka A
- Kalfon P
- Kamali E
- Kaminsky GE
- Kaneko M
- Kang M
- Kang M
- Kang PL
- Kang PL
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- Kang Y
- Kao KC
- Kappler F
- Kara A
- Karachi F
- Karanjia N
- Karbing DS
- Karsten E
- Kasdan H
- Kashiya S
- Kashyap R
- Katabami K
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- Katabami K
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- Katira BH
- Kavanagh BP
- Kawamura N
- Kawano S
- Kay FU
- Kayaaslan B
- Kayambu G
- Kazutoshi F
- Ke MW
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- Keep J
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- Kellner F
- Kelly JM
- Kenardy J
- Keough E
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- Kerr C
- Kezyte G
- Khadjibaev A
- Khaliq W
- Khine H
- Kim DJ
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- Kim KS
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- Kim MH
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- Kim W
- Kimmoun A
- King HS
- Kinnear J
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- Kirakli C
- Kirca H
- Kirman M
- Kirwan CJ
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- Klaus DA
- Kleinpell R
- Kluge S
- Knafelj R
- Knight LD
- Ko JI
- Ko SB
- Kobayashi A
- Koco E
- Kodate A
- Kodate A
- Kodate A
- Kokkini S
- Kolnikova I
- Komuro T
- Kondili E
- Kongpolprom N
- Kooner G
- Kostalas M
- Kosuk ME
- Kotsopoulos A
- Kou PS
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- Kovacikova L
- Kox M
- Kraegpoeth A
- Krenn CG
- Krishna B
- Kristof J
- Kruger A
- Kruger A
- Krüger A
- Ku NS
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- Kubik M
- Kubota K
- Kuebler WM
- Kulaga EV
- Kulkarni AP
- Kumari BK
- Kumbamu A
- Kunze-Szikszay N
- Kurmukov IA
- Kurth T
- Kurtz P
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- Kwon HM
- Kwon HM
- Kwon WY
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- Kye YC
- Kyle UG
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- Labaune MA
- Labra C
- Lacerda P
- Laerkner E
- Lafaurie M
- Lafuente E
- Lagonidis D
- Lagos R
- Lahmer T
- Lai CC
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- Latini R
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- Latini R
- Latorre J
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- Laureys S
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- Legrand M
- Legrand M
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- Leitao AL
- Leite RT
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- Leone M
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- Lerma FA
- Lesmes SP
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- Li SH
- Liao X
- Lichtenstein D
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- Limuti R
- Lin KC
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- Lin WC
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- Lischinsky A
- Lissonde F
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- Litchfield K
- Liu CP
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- Liu D
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- Llorente B
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- Lobato MS
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- Loizou C
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- Longhi L
- Lopes JA
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- Lopez-Gude MJ
- Lorini L
- Lortat-Jacob B
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- Lotay R
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- Louf-Durier A
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- Louis B
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- Lukaszewicz AC
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- MacKay A
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- Macrì M
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- Maekawa K
- Maekawa K
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- Magnoni S
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- Maistry N
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- Mengelle C
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- Mezidi M
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- Okayama Research Investigation Organizing Network (ORION)investigators
- Olaechea P
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- Stamm J
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- Street H
- Stretti F
- Struijs A
- Stubbs C
- Stubbs C
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- WIND study group
- WIND study group
- WIND study group
- Winder-Rhodes S
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- Zýková I
- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Search for Dark Matter and Supersymmetry with a Compressed Mass Spectrum in the Vector Boson Fusion Topology in Proton-Proton Collisions at root s=8 TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Abu Zeid S
- Ackert A
- Acosta D
- Acosta JG
- Adair A
- Adam W
- Adams JR
- Adams MR
- Adams T
- Adiguzel A
- Adzic P
- Agapitos A
- Aggleton R
- Agram J-L
- Ahmad A
- Ahmad M
- Ahmad M
- Ahmed I
- Ahuja S
- Akchurin N
- Akgun B
- Al-bataineh A
- Albergo S
- Albrow M
- Alcaraz Maestre J
- Aldaya Martin M
- Alderweireldt S
- Aldá Júnior WL
- Aleksandrov A
- Alexander J
- Alimena J
- Almond J
- Alunni Solestizi L
- Alverson G
- Alves FL
- Alves GA
- Alyari M
- Amapane N
- Amsler C
- Anagnostou G
- Anderson D
- Anderson I
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- Andreev V
- Andreev Yu
- Andrews MB
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- Antropov I
- Antunovic Z
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- Apollinari G
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- Bagliesi G
- Bahinipati S
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- Bakhshiansohi H
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- Bartók M
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- Publication venue
- Publication date
- 01/01/2016
- Field of study
Peer reviewe
Observation of a New Excited Beauty Strange Baryon Decaying to Ξb- π+π-
- Author
- Aarrestad TK
- Aarup Petersen H
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
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- Yi K
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- Yohay R
- Yoo HD
- Yoo J
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- Yu PR
- Yu SS
- Yuan L
- Yuan S
- Yumiceva F
- Yusli MN
- Zabi A
- Zacharopoulou A
- Zahid S
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zecchinelli AG
- Zeinali M
- Zeuner WD
- Zghiche A
- Zhang F
- Zhang H
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- Zhao J
- Zhizhin I
- Zhokin A
- Zhu DH
- Zhu RY
- Ziemons T
- Zientek M
- Zlebcik R
- Zoi I
- Zolkapli Z
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- Zorbilmez C
- Zotto P
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- Zuolo D
- Zygala L
- Álvarez Fernández A
- Özçelik Ö
- Publication venue
- American Physical Society
- Publication date
- 01/01/2021
- Field of study
The Ξb-π+π- invariant mass spectrum is investigated with an event sample of proton-proton collisions at s=13 TeV, collected by the CMS experiment at the LHC in 2016-2018 and corresponding to an integrated luminosity of 140 fb-1. The ground state Ξb- is reconstructed via its decays to J/ψΞ- and J/ψΛK-. A narrow resonance, labeled Ξb(6100)-, is observed at a Ξb-π+π- invariant mass of 6100.3±0.2(stat)±0.1(syst)±0.6(Ξb-) MeV, where the last uncertainty reflects the precision of the Ξb- baryon mass. The upper limit on the Ξb(6100)- natural width is determined to be 1.9 MeV at 95% confidence level. The low Ξb(6100)- signal yield observed in data does not allow a measurement of the quantum numbers of the new state. However, following analogies with the established excited Ξc baryon states, the new Ξb(6100)- resonance and its decay sequence are consistent with the orbitally excited Ξb- baryon, with spin and parity quantum numbers JP=3/2-
Measurement of the inclusive and differential Higgs boson production cross sections in the decay mode to a pair of τ Leptons in pp collisions at sqrt[s]=13 TeV
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- Tully C
- Tumasyan A
- Tuo S
- Tuominen E
- Tuominiemi J
- Turini N
- Turkcapar S
- Tuuva T
- Tuve C
- Tytgat M
- Tyurin N
- Tziaferi E
- Uchida K
- Ujvari B
- Ulmer KA
- Ulrich R
- Uniyal R
- Uplegger L
- Urda Gómez L
- Uribe Estrada C
- Usai E
- Uvarov L
- Uzunian A
- Vaandering EW
- Vagnerini A
- Vai I
- Valencia Palomo L
- Valsecchi D
- Valuev V
- Van De Klundert M
- Van Der Linden J
- Van Doninck W
- Van Hove P
- Van Mechelen P
- Van Mulders P
- Van Onsem GP
- Van Putte S
- Van Remortel N
- Vanden Bemden M
- Vander Donckt M
- Vander Velde C
- Vanlaer P
- Varela J
- Varelas N
- Vargas Hernandez AM
- Vartak A
- Vats D
- Vazquez Valencia F
- Vazzoler F
- Veckalns V
- Veelken C
- Velasco M
- Velkovska J
- Vellidis K
- Venditti R
- Venturi A
- Verdini PG
- Veres GI
- Vermassen B
- Verwilligen P
- Veszpremi V
- Vetens W
- Viazlo O
- Vico Villalba C
- Vigilante L
- Viinikainen J
- Vila I
- Vilela Pereira A
- Viliani L
- Virdee T
- Virdi AK
- Viret S
- Vischia P
- Vit M
- Vitulo P
- Vizan Garcia JM
- Vlasov E
- Vlimant JR
- Vojinovic M
- Volkov A
- Volkov S
- Volobouev I
- Von Cube RF
- Vorobyev A
- Vourliotis E
- Voutilainen M
- Voytishin N
- Vámi TÁ
- Wadud MA
- Wagner SR
- Walkingshaw Pass K
- Wallny R
- Walsh R
- Waltenberger W
- Walter D
- Wamorkar T
- Wan Abdullah WAT
- Wanczyk J
- Wang B
- Wang C
- Wang D
- Wang F
- Wang H
- Wang J
- Wang J
- Wang J
- Wang L
- Wang Q
- Wang Q
- Wang S
- Wang X
- Wang Y
- Wang Z
- Wang Z
- Waqas M
- Wardle N
- Warner Z
- Wassmer M
- Watson IJ
- Wayne M
- Webb SN
- Weber HA
- Weber M
- Wei K
- Wen Y
- Wertz S
- West C
- Wezenbeek L
- Whitbeck A
- White R
- White S
- Wichmann K
- Wickramage N
- Wickramarathna DDC
- Wiedenbeck S
- Wieland S
- Wiens L
- Wightman A
- Williams A
- Williams J
- Williams T
- Willmott C
- Wilson G
- Wilson J
- Wimpenny S
- Winer BL
- Winterbottom D
- Wisecarver A
- Wissing C
- Wittich P
- Wolf R
- Wolfe E
- Wong K
- Wong WY
- Wood D
- Wozniak KA
- Wozniewski S
- Wright D
- Wu HY
- Wu Z
- Wuchterl S
- Wulz C-E
- Wunsch S
- Wyslouch B
- Würthwein F
- Xiang Y
- Xiao J
- Xiao M
- Xiao R
- Xie S
- Xie W
- Yagil A
- Yalvac M
- Yan F
- Yan X
- Yang S
- Yang S
- Yang UK
- Yang YC
- Yao Y
- Yarar H
- Yates BR
- Yazgan E
- Ye Z
- Yetkin EA
- Yi K
- Yigitbasi E
- Yohay R
- Yoo HD
- Yoo J
- Yoon I
- You Z
- Yu D
- Yu GB
- Yu I
- Yu PR
- Yu SS
- Yuan L
- Yuan S
- Yuldashev BS
- Yumiceva F
- Yusli MN
- Zabi A
- Zacharopoulou A
- Zahid S
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zecchinelli AG
- Zeinali M
- Zeuner WD
- Zghiche A
- Zhang F
- Zhang H
- Zhang J
- Zhang L
- Zhang W
- Zhang Y
- Zhang Y
- Zhang Z
- Zhao J
- Zhizhin I
- Zhokin A
- Zhu DH
- Zhu RY
- Ziemons T
- Zoi I
- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
- Zotto P
- Zotz A
- Zou D
- Zou R
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Álvarez Fernández A
- Özçelik Ö
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
Measurements of the inclusive and differential fiducial cross sections of the Higgs boson are presented, using the τ lepton decay channel. The differential cross sections are measured as functions of the Higgs boson transverse momentum, jet multiplicity, and transverse momentum of the leading jet in the event, if any. The analysis is performed using proton-proton collision data collected with the CMS detector at the LHC at a center-of-mass energy of 13 TeV and corresponding to an integrated luminosity of 138 fb^{-1}. These are the first differential measurements of the Higgs boson cross section in the final state of two τ leptons. In final states with a large jet multiplicity or with a Lorentz-boosted Higgs boson, these measurements constitute a significant improvement over measurements performed in other final states
The evaluation of a remote support program on quality of life and evolution of disease in COPD patients with frequent exacerbations
- Author
- AJ Mackay
- Alonso Fernández-Nistal
- Antonia Fuster
- Aurelio Arnedillo
- Bernardino Alcazar
- CA Camargo
- CR Wetering van
- E Monninkhof
- F Andersson
- G Moullec
- GC Donaldson
- H Karapolat
- IG Tsiligianni
- J Bourbeau
- J Bourbeau
- J Garcia-Aymerich
- J Vestbo
- JA Wedzicha
- JJ Soler-Cataluña
- Joan B. Soriano
- Jose Miguel Rodríguez González-Moro
- JR Curtis
- JR Hurst
- JY Tan
- KL Rice
- KR Chapman
- M Blanco-Aparicio
- M Carone
- M Mehring
- M Miravitlles
- M Voll-Aanerud
- María José Espinosa de los Monteros
- MD Eisner
- MW Rich
- O Hermiz
- OE Eva
- Patricia García Sidro
- PG Gibson
- Pilar de Lucas
- PW Jones
- R Garrod
- R Güell
- S Stock
- SD Lee
- SG Adams
- SJC Taylor
- T Bodenheimer
- T Hajiro
- T Molen van der
- T Wilkinson
- TA Seemungal
- TA Seemungal
- TMA Wilkinson
- XM Yang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Why do microorganisms produce rhamnolipids?
- Author
- A Darzins
- A Oberbremer
- A Zgoła-Grześkowiak
- AJ Wolfe
- AK Koch
- AL Goodman
- AM Abdel-Mawgoud
- AR Johnsen
- AR Johnsen
- BR Boles
- BR Boles
- CA Boulton
- CB Whitchurch
- CN Mulligan
- CN Mulligan
- CO Obuekwe
- CO Obuekwe
- D Dubeau
- DC Bergmans
- DF Falatko
- DG Allison
- DJ Hassett
- DK Jain
- E Déziel
- E Déziel
- E Déziel
- E Haba
- E Kaczorek
- F Fernández-Luqueño
- FA Volkering
- G O’Toole
- G Soberón-Cháves
- G Soberón-Chávez
- G Zeng
- GA O’Toole
- GM Fraser
- H Górna
- HD Kulasekara
- HP Hahn
- I Ventre
- J Mata-Sandoval
- J Tremblay
- JA Girón
- JA Shapiro
- JD Desai
- JH Merritt
- JL Parra
- JS Webb
- JW Costerton
- JW Hickman
- JW Hickman
- K Czaczyk
- K Heurlier
- K Myszka
- K Myszka
- K Sauer
- K Taguchi
- Katarzyna Czaczyk
- KM Thormann
- KS Ishimoto
- KT Hisatsuka
- L Chrzanowski
- L Chrzanowski
- L Chrzanowski
- L Chrzanowski
- L Chrzanowski
- L Chrzanowski
- L Chrzanowski
- L Chrzanowski
- L Friedman
- L Guerra-Santos
- L Guerra-Santos
- LA Morici
- M Bouchez
- M Bouchez-Naïtali
- M Espinosa-Urgel
- M Espinosa-Urgel
- M Gennip Van
- M Goldflam
- M Hausner
- M Hobbs
- M Humphries
- M Matsufuji
- M Nitschke
- M Owsianiak
- M Owsianiak
- M Sharma
- M Whiteley
- MA Manresa
- ME Davey
- ME Davey
- ME Singer
- MR Parsek
- MR Parsek
- N Verstraeten
- NA Roberts
- NC Caiazza
- P Stoodley
- P Stoodley
- P Vatsa
- PS Meadows
- PS Stewart
- Q Wang
- R Beal
- R Glick
- R Rahim
- RA Al-Tahhan
- RC Prince
- RK Hommel
- RM Maier
- RM Miller
- RS Makkar
- S Arino
- S Arino
- S Lang
- S Wilhelm
- SJ Pamp
- SK Kim
- SL Kuchma
- SL Kuchma
- SM Hunt
- SR Schooling
- T Köhler
- TR Neu
- U Jenal
- UA Ochsner
- UA Ochsner
- W Finnerty
- WH Noordman
- Y Irie
- Y Lequette
- Y Zhang
- Y Zhang
- Y Zhang
- Z Dai
- Z Wang
- Łukasz Chrzanowski
- Łukasz Ławniczak
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
- …