533 research outputs found

    Towards the Continuum Limit of the Overlap Quark Propagator in Landau Gauge

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    The properties of the momentum space quark propagator in Landau gauge are examined for the overlap quark action in quenched lattice QCD. Numerical calculations were done on two lattices with different lattice spacing aa and similar physical volumes to explore the quark propagator in the continuum limit. We have calculated the nonperturbative wavefunction renormalization function Z(p)Z(p) and the nonperturbative mass function M(p)M(p) for a variety of bare quark masses and perform a simple linear extrapolation to the chiral limit. We find the behaviour of Z(p)Z(p) and M(p)M(p) in the chiral limit are in good agreement between the two lattices.Comment: 3 pages, 2 figures, talk, Lattice2002(Chiral Fermion

    Nonperturbative renormalisation of composite operators with overlap quarks

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    We compute non-perturbatively the renormalisation constants of composite operators on a 163×3216^3 \times 32 lattice with lattice spacing aa = 0.093 fm for the overlap fermion action by using the regularisation independent (RI) scheme. The quenched gauge configurations are generated by tadpole improved plaquette plus rectangle action. We test the perturbative continuum relation ZA=ZVZ_A = Z_V and ZS=ZP Z_S=Z_P and find that they agree well above μ\mu = 1.6 GeV. We also perform a Renormalisation Group analysis at the next-to-next-to-leading order and convert the renormalisation constants to the MSˉ\bar{MS} scheme.Comment: Talk given at LHP2003, Cairns, Australi

    Flavour constraints on scenarios with two or three heavy squark generations

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    We re-assess constraints from flavour-changing neutral currents in the kaon system on supersymmetric scenarios with a light gluino, two heavy generations of squarks and a lighter third generation. We compute for the first time limits in scenarios with three heavy squark families, taking into account QCD corrections at the next-to-leading order. We compare our limits with those in the case of two heavy families. We use the mass insertion approximation and consider contributions from gluino exchange to constrain the mixing between the first and second squark generation. While it is not possible to perform a general analysis, we assess the relevance of each kind of flavour- and CP-violating parameters. We also provide ready to use magic numbers for the computation of the Wilson coefficients at 2 GeV for these scenarios.Comment: 23 pages, 14 figures; v3: matches published version (contains improvements in the presentation and clarifications

    Safety Outcomes and Near-Adult Height Gain of Growth Hormone-Treated Children with SHOX Deficiency: Data from an Observational Study and a Clinical Trial

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    Background/Aims: To assess auxological and safety data for growth hormone (GH)-Treated children with SHOX deficiency. Methods: Data were examined for GH-Treated SHOX-deficient children (n = 521) from the observational Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS). For patients with near-Adult height information, GeNeSIS results (n = 90) were compared with a clinical trial (n = 28) of SHOX-deficient patients. Near-Adult height was expressed as standard deviation score (SDS) for chronological age, potentially increasing the observed effect of treatment. Results: Most SHOX-deficient patients in GeNeSIS had diagnoses of Leri-Weill syndrome (n = 292) or non-syndromic short stature (n = 228). For GeNeSIS patients with near-Adult height data, mean age at GH treatment start was 11.0 years, treatment duration 4.4 years, and height SDS gain 0.83 (95% confidence interval 0.49-1.17). Respective ages, GH treatment durations and height SDS gains for GeNeSIS patients prepubertal at baseline (n = 42) were 9.2 years, 6.0 years and 1.19 (0.76-1.62), and for the clinical trial cohort they were 9.2 years, 6.0 years and 1.25 (0.92-1.58). No new GH-related safety concerns were identified. Conclusion: Patients with SHOX deficiency who had started GH treatment before puberty in routine clinical practice had a similar height gain to that of patients in the clinical trial on which approval for the indication was based, with no new safety concerns

    Topology, Entropy and Witten Index of Dilaton Black Holes

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    We have found that for extreme dilaton black holes an inner boundary must be introduced in addition to the outer boundary to give an integer value to the Euler number. The resulting manifolds have (if one identifies imaginary time) topology S1×R×S2S^1 \times R \times S^2 and Euler number χ=0\chi = 0 in contrast to the non-extreme case with χ=2\chi=2. The entropy of extreme U(1)U(1) dilaton black holes is already known to be zero. We include a review of some recent ideas due to Hawking on the Reissner-Nordstr\"om case. By regarding all extreme black holes as having an inner boundary, we conclude that the entropy of {\sl all} extreme black holes, including [U(1)]2[U(1)]^2 black holes, vanishes. We discuss the relevance of this to the vanishing of quantum corrections and the idea that the functional integral for extreme holes gives a Witten Index. We have studied also the topology of ``moduli space'' of multi black holes. The quantum mechanics on black hole moduli spaces is expected to be supersymmetric despite the fact that they are not HyperK\"ahler since the corresponding geometry has torsion unlike the BPS monopole case. Finally, we describe the possibility of extreme black hole fission for states with an energy gap. The energy released, as a proportion of the initial rest mass, during the decay of an electro-magnetic black hole is 300 times greater than that released by the fission of an 235U{}^{235} U nucleus.Comment: 51 pages, 4 figures, LaTeX. Considerably extended version. New sections include discussion of the Witten index, topology of the moduli space, black hole sigma model, and black hole fission with huge energy releas

    Stellar structure and compact objects before 1940: Towards relativistic astrophysics

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    Since the mid-1920s, different strands of research used stars as "physics laboratories" for investigating the nature of matter under extreme densities and pressures, impossible to realize on Earth. To trace this process this paper is following the evolution of the concept of a dense core in stars, which was important both for an understanding of stellar evolution and as a testing ground for the fast-evolving field of nuclear physics. In spite of the divide between physicists and astrophysicists, some key actors working in the cross-fertilized soil of overlapping but different scientific cultures formulated models and tentative theories that gradually evolved into more realistic and structured astrophysical objects. These investigations culminated in the first contact with general relativity in 1939, when J. Robert Oppenheimer and his students George Volkoff and Hartland Snyder systematically applied the theory to the dense core of a collapsing neutron star. This pioneering application of Einstein's theory to an astrophysical compact object can be regarded as a milestone in the path eventually leading to the emergence of relativistic astrophysics in the early 1960s.Comment: 83 pages, 4 figures, submitted to the European Physical Journal

    Subclinical Thyroid Dysfunction and Fracture Risk: A Meta-analysis

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    IMPORTANCE Associations between subclinical thyroid dysfunction and fractures are unclear and clinical trials are lacking. OBJECTIVE To assess the association of subclinical thyroid dysfunction with hip, nonspine, spine, or any fractures. DATA SOURCES AND STUDY SELECTION The databases of MEDLINE and EMBASE (inception to March 26, 2015) were searched without language restrictions for prospective cohort studies with thyroid function data and subsequent fractures. DATA EXTRACTION Individual participant data were obtained from 13 prospective cohorts in the United States, Europe, Australia, and Japan. Levels of thyroid function were defined as euthyroidism (thyroid-stimulating hormone [TSH], 0.45-4.49 mIU/L), subclinical hyperthyroidism (TSH <0.45 mIU/L), and subclinical hypothyroidism (TSH ≥4.50-19.99 mIU/L) with normal thyroxine concentrations. MAIN OUTCOME AND MEASURES The primary outcome was hip fracture. Any fractures, nonspine fractures, and clinical spine fractures were secondary outcomes. RESULTS Among 70,298 participants, 4092 (5.8%) had subclinical hypothyroidism and 2219 (3.2%) had subclinical hyperthyroidism. During 762,401 person-years of follow-up, hip fracture occurred in 2975 participants (4.6%; 12 studies), any fracture in 2528 participants (9.0%; 8 studies), nonspine fracture in 2018 participants (8.4%; 8 studies), and spine fracture in 296 participants (1.3%; 6 studies). In age- and sex-adjusted analyses, the hazard ratio (HR) for subclinical hyperthyroidism vs euthyroidism was 1.36 for hip fracture (95% CI, 1.13-1.64; 146 events in 2082 participants vs 2534 in 56,471); for any fracture, HR was 1.28 (95% CI, 1.06-1.53; 121 events in 888 participants vs 2203 in 25,901); for nonspine fracture, HR was 1.16 (95% CI, 0.95-1.41; 107 events in 946 participants vs 1745 in 21,722); and for spine fracture, HR was 1.51 (95% CI, 0.93-2.45; 17 events in 732 participants vs 255 in 20,328). Lower TSH was associated with higher fracture rates: for TSH of less than 0.10 mIU/L, HR was 1.61 for hip fracture (95% CI, 1.21-2.15; 47 events in 510 participants); for any fracture, HR was 1.98 (95% CI, 1.41-2.78; 44 events in 212 participants); for nonspine fracture, HR was 1.61 (95% CI, 0.96-2.71; 32 events in 185 participants); and for spine fracture, HR was 3.57 (95% CI, 1.88-6.78; 8 events in 162 participants). Risks were similar after adjustment for other fracture risk factors. Endogenous subclinical hyperthyroidism (excluding thyroid medication users) was associated with HRs of 1.52 (95% CI, 1.19-1.93) for hip fracture, 1.42 (95% CI, 1.16-1.74) for any fracture, and 1.74 (95% CI, 1.01-2.99) for spine fracture. No association was found between subclinical hypothyroidism and fracture risk. CONCLUSIONS AND RELEVANCE Subclinical hyperthyroidism was associated with an increased risk of hip and other fractures, particularly among those with TSH levels of less than 0.10 mIU/L and those with endogenous subclinical hyperthyroidism. Further study is needed to determine whether treating subclinical hyperthyroidism can prevent fractures

    Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

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    A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results
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