INFLUENCE OF FREQUENCY OF FERMENTED MILK PRODUCTS CONSUMPTION IN PERSONS WITH HYPERINSULINEMIA AND ELEVATED BODY MASS ON THE DEGREE OF INSULIN RESISTANCE

Fermented dairy products with a low percentage of fat play a role in modulating the function of β-cells of the pancreas and increased sensitivity to insulin. The purpose of this research is to verify the influence of the type and quantity, of consumed fermented milk products (yogurt and kefir), on the degree of insulin resistance, through Homeostatic Model Assessment for Insulin Resistance (HOMA-IR). The research was conducted on 175 people, from whom 103 women and 73 men, aged 25 to 75 years, with hyperinsulinemia and have increased body mass. Respondents were interviewed with a survey questionnaire that refers to the frequency, quantity, and type of consumed fermented milk products with different percentages of fats. From the obtained results, 56 (32%) have a habit of daily consumption, and the most frequently used daily amount is 250 mL in 127 (74.70%) participants. Statistical significance (p=0.015) was determined between the frequency of consumption and HOMA-IR in the age group between 41 and 55 years. The participants of this age group who have a higher value of the index tend to consume fermented milk products more often, which leads to the conclusion that the consumption of the fermented milk products can have an impact on HOMA-IR in this age group. The statistical analysis of the results obtained for the age groups: 25 to 40 years, and 56 to 75 years showed that there is no significant difference between the frequency of fermented dairy products consumption and HOMA-IR index of the subjects in the groups

A global experiment on motivating social distancing during the COVID-19 pandemic

Finding communication strategies that effectively motivate social distancing continues to be a global public health priority during the COVID-19 pandemic. This cross-country, preregistered experiment (n = 25,718 from 89 countries) tested hypotheses concerning generalizable positive and negative outcomes of social distancing messages that promoted personal agency and reflective choices (i.e., an autonomy-supportive message) or were restrictive and shaming (i.e., a controlling message) compared with no message at all. Results partially supported experimental hypotheses in that the controlling message increased controlled motivation (a poorly internalized form of motivation relying on shame, guilt, and fear of social consequences) relative to no message. On the other hand, the autonomy-supportive message lowered feelings of defiance compared with the controlling message, but the controlling message did not differ from receiving no message at all. Unexpectedly, messages did not influence autonomous motivation (a highly internalized form of motivation relying on one’s core values) or behavioral intentions. Results supported hypothesized associations between people’s existing autonomous and controlled motivations and self-reported behavioral intentions to engage in social distancing. Controlled motivation was associated with more defiance and less long-term behavioral intention to engage in social distancing, whereas autonomous motivation was associated with less defiance and more short- and long-term intentions to social distance. Overall, this work highlights the potential harm of using shaming and pressuring language in public health communication, with implications for the current and future global health challenges

A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.

The COVID-19 pandemic has increased negative emotions and decreased positive emotions globally. Left unchecked, these emotional changes might have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we tested the effectiveness of reappraisal, an emotion-regulation strategy that modifies how one thinks about a situation. Participants from 87 countries and regions (n = 21,644) were randomly assigned to one of two brief reappraisal interventions (reconstrual or repurposing) or one of two control conditions (active or passive). Results revealed that both reappraisal interventions (vesus both control conditions) consistently reduced negative emotions and increased positive emotions across different measures. Reconstrual and repurposing interventions had similar effects. Importantly, planned exploratory analyses indicated that reappraisal interventions did not reduce intentions to practice preventive health behaviours. The findings demonstrate the viability of creating scalable, low-cost interventions for use around the world

Immature Ovarian Teratoma

We present our experience of diagnosing immature ovarian teratoma with 2D and 3D vaginal ultrasound. A 29-year-old female patient with no symptoms was examined for routine gynecology examination before the start of an in vitro fertilization program. The patient had two previous surgeries both for ovarian cystectomy and histopathology finding of mature cystic ovarian teratoma. Left oophorectomy was performed for complex ovarian mass that demonstrated immature ovarian teratoma on final pathology. The neoplasm was well-differentiating (low-grade), according to two-tiered (low- and high-grade) system, and in IA stage, according to the Union for International Cancer Control (UICC) and American Joint Committee on Cancer (AJCC). The oncologist's council proposed that no treatment is needed. Keywords: 2D/3D ultrasonography, Immature teratoma, Ovarian teratoma. Donald School Journal of Ultrasound in Obstetrics and Gynecology (2020): 10.5005/jp-journals-10009-167

Novel method of treating ovarian infertility: is Platelet-Rich Plasma a new promising therapy in the future?

Introduction. In today's modern society, the treatment of patients with poor ovarian reserve presents a medical challenge of increased clinical importance. The use of platelet-rich plasma (PRP) is a new hope that improves pregnancy chances. Increased use of the PRP in a number of in vitro centers around the world as well as publication of the first experience in in vitro fertilization entailed the need for this systematic review. Methods. PubMed, Cochrane and Ovid Medline were searched between 2000 and 2019 under the following strategy: [ and and ]. Fourteen original articles published in medical scientific journals were analyzed in this study. The evidence level and quality assessment were made based on the most up-to-date, reliable, scientific evidence as well as from the number of additional relevant citations. Results. Taking the current available proof and evidence into consideration, we can conclude that the PRP method improves the ovarian function and increases the chances of clinical pregnancy. In addition, we assume that, over time, the PRP method objectively improves the ovarian reserves. Recent studies support the theory of increasing the number of preantral follicles, followed by appropriate growth and reduction of follicular atresia. Conclusion. The improvement of the quantity and quality of oocytes with the intra-ovarian application of PRP potentially suggests a new concept of ovarian aging, where the ovarian microenvironment plays a crucial role

Different Timing of Adjuvant Low Dose hCG and GnRH Agonist Trigger Protocol, in OHSS High-Risk Patient with Peak E2 Level <4000 pg/mL

Objective: The aim of the study is to compare the live birth rates between 1,500 I.U. of Human chorionic gonadotropin at the time of Gonadotropin-releasing hormone agonist trigger day or 35-36 h later on the oocyte pick-up day, without affecting the risk of significant ovarian hyperstimulation syndrome development in high-risk patients with peak E2 level <4,000 pg/m

Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice

Pregnant women are at high risk for severe influenzadisease outcomes, yet insights into the underlyingmechanisms are limited. Here, we present models ofH1N1 infection in syngenic and allogenic pregnantmice; infection in the latter mirrors the severe courseof 2009 pandemic influenza in pregnant women. Wefound that the anti-viral immune response in the pregnanthost was significantly restricted as compared tothe non-pregnant host. This included a reduced type Iinterferon response as well as impaired migration ofCD8+ T cells into the lung. The multi-faceted failureto mount an anti-viral response in allogenic pregnantmice resulted in a less stringent selective environmentthat promoted the emergence of 2009 H1N1 virusvariants that specifically counteract type I interferonresponse and mediate increased viral pathogenicity.These insights underscore the importance of influenzavaccination compliance in pregnant womenand may open novel therapeutic avenues.Fil: Engels, Géraldine. University Medical Center Hamburg-Eppendorf; Alemania. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Hierweger, Alexandra Maximiliane. University Medical Center Hamburg-Eppendorf; AlemaniaFil: Hoffmann, Julia. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Thieme, René. University Medical Center Hamburg-Eppendorf; AlemaniaFil: Thiele, Swantje. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Bertram, Stephanie. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Dreier, Carola. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Resa-Infante, Patricia. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Jacobsen, Henning. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Thiele, Kristin. University Medical Center Hamburg-Eppendorf; AlemaniaFil: Alawi, Malik. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Indenbirken, Daniela. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Grundhoff, Adam. Leibniz Institut Für Experimentelle Virologie; AlemaniaFil: Siebels, Svenja. University Medical Center Hamburg-Eppendorf; AlemaniaFil: Fischer, Nicole. University Medical Center Hamburg-Eppendorf; AlemaniaFil: Stojanovska, Violeta. University of Groningen; Países BajosFil: Muzzio, Damián Oscar. University of Greifswald; AlemaniaFil: Jensen, Cristian Federico. University of Greifswald; Alemania. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Karimi, Khalil. University Medical Center Hamburg-Eppendorf; AlemaniaFil: Mittrücker, Hans-Willi. University Medical Center Hamburg-Eppendorf; AlemaniaFil: Arck, Petra Clara. University Medical Center Hamburg-Eppendorf; AlemaniaFil: Gabriel, Gülsah. Leibniz Institut Für Experimentelle Virologie; Alemani

Author Correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.

Correction to: Nature Human Behaviour https://doi.org/10.1038/s41562-021-01173-x, published online 2 August 2021. In the version of this article initially published, the following authors were omitted from the author list and the Author contributionssection for “investigation” and “writing and editing”: Nandor Hajdu (Institute of Psychology, ELTE Eötvös Loránd University, Budapest,Hungary), Jordane Boudesseul (Facultad de Psicología, Instituto de Investigación Científica, Universidad de Lima, Lima, Perú), RafałMuda (Faculty of Economics, Maria Curie-Sklodowska University, Lublin, Poland) and Sandersan Onie (Black Dog Institute, UNSWSydney, Sydney, Australia & Emotional Health for All Foundation, Jakarta, Indonesia). In addition, Saeideh FatahModares’ name wasoriginally misspelled as Saiedeh FatahModarres in the author list. Further, affiliations have been corrected for Maria Terskova (NationalResearch University Higher School of Economics, Moscow, Russia), Susana Ruiz Fernandez (FOM University of Applied Sciences,Essen; Leibniz-Institut fur Wissensmedien, Tubingen, and LEAD Research Network, Eberhard Karls University, Tubingen, Germany),Hendrik Godbersen (FOM University of Applied Sciences, Essen, Germany), Gulnaz Anjum (Department of Psychology, Simon FraserUniversity, Burnaby, Canada, and Department of Economics & Social Sciences, Institute of Business Administration, Karachi, Pakistan)

Author correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

Correction to: Nature Human Behaviour https://doi.org/10.1038/s41562-021-01173-x, published online 2 August 2021. In the version of this article initially published, the following authors were omitted from the author list and the Author contributionssection for “investigation” and “writing and editing”: Nandor Hajdu (Institute of Psychology, ELTE Eötvös Loránd University, Budapest,Hungary), Jordane Boudesseul (Facultad de Psicología, Instituto de Investigación Científica, Universidad de Lima, Lima, Perú), RafałMuda (Faculty of Economics, Maria Curie-Sklodowska University, Lublin, Poland) and Sandersan Onie (Black Dog Institute, UNSWSydney, Sydney, Australia & Emotional Health for All Foundation, Jakarta, Indonesia). In addition, Saeideh FatahModares’ name wasoriginally misspelled as Saiedeh FatahModarres in the author list. Further, affiliations have been corrected for Maria Terskova (NationalResearch University Higher School of Economics, Moscow, Russia), Susana Ruiz Fernandez (FOM University of Applied Sciences,Essen; Leibniz-Institut fur Wissensmedien, Tubingen, and LEAD Research Network, Eberhard Karls University, Tubingen, Germany),Hendrik Godbersen (FOM University of Applied Sciences, Essen, Germany), Gulnaz Anjum (Department of Psychology, Simon FraserUniversity, Burnaby, Canada, and Department of Economics & Social Sciences, Institute of Business Administration, Karachi, Pakistan)

In COVID-19 Health Messaging, Loss Framing Increases Anxiety with Little-to-No Concomitant Benefits: Experimental Evidence from 84 Countries.

The COVID-19 pandemic (and its aftermath) highlights a critical need to communicate health information effectively to the global public. Given that subtle differences in information framing can have meaningful effects on behavior, behavioral science research highlights a pressing question: Is it more effective to frame COVID-19 health messages in terms of potential losses (e.g., "If you do not practice these steps, you can endanger yourself and others") or potential gains (e.g., "If you practice these steps, you can protect yourself and others")? Collecting data in 48 languages from 15,929 participants in 84 countries, we experimentally tested the effects of message framing on COVID-19-related judgments, intentions, and feelings. Loss- (vs. gain-) framed messages increased self-reported anxiety among participants cross-nationally with little-to-no impact on policy attitudes, behavioral intentions, or information seeking relevant to pandemic risks. These results were consistent across 84 countries, three variations of the message framing wording, and 560 data processing and analytic choices. Thus, results provide an empirical answer to a global communication question and highlight the emotional toll of loss-framed messages. Critically, this work demonstrates the importance of considering unintended affective consequences when evaluating nudge-style interventions