Implementación de un programa piloto de servicios farmacéuticos en una población rural de Veracruz (México) con alta prevalencia de enfermedades crónico-degenerativas

Objetivo: Implementar un programa piloto de servicios farmacéuticos de carácter comunitario en una población rural de la zona centro de Veracruz (México) con una alta prevalencia de enfermedades crónico-degenerativas. Material y métodos: Consistió en dos fases: 1) identificación y caracterización de la población, y 2) implementación del programa piloto de los servicios farmacéuticos. El análisis estadístico se realizó con paquete estadístico STATA (versión 9.0). Resultados: Se le ofreció el servicio a una población de 904 personas, de las que 897 participaron; de estas últimas, 436 presentaron valores alterados de las patologías incluidas en el estudio. Para evaluar el efecto de la intervención farmacéutica sobre la efectividad de los tratamientos farmacológicos, se observó que en el grupo con hipertrigliceridemia, hipercolesterolemia y diabetes mellitus tipo 2 se produjo una disminución estadísticamente significativa de las concentraciones séricas de triglicéridos, colesterol y glucosa (p <0,001), respectivamente. De igual manera, se observó una reducción de la presión arterial diastólica y sistólica (p <0,001) después de la intervención. La evaluación clínica de los pacientes al final del tratamiento que incluyó servicios farmacéuticos fue en sentido favorable, ya que el 82,56% de la población de estudio refirió valores controlados dentro de las patologías de estudio y valores estadísticamente significativos (p <0,001). Los resultados negativos asociados a la medicación identificados fueron del tipo inefectividad cuantitativa, y se detectaron 14 reacciones adversas a medicamentos tipo A. Conclusiones: La atención farmacéutica es una estrategia idónea para actuar en el complejo proceso de generación y protección de la salud en comunidades vulnerables, como son las rurales con poblaciones con enfermedades crónico-degenerativas

Implementación de un programa piloto de servicios farmacéuticos en una población rural de Veracruz (México) con alta prevalencia de enfermedades crónico-degenerativas

Objetivo: Implementar un programa piloto de servicios farmacéuticos de carácter comunitario en una población rural de la zona centro de Veracruz (México) con una alta prevalencia de enfermedades crónico-degenerativas. Material y métodos: Consistió en dos fases: 1) identificación y caracterización de la población, y 2) implementación del programa piloto de los servicios farmacéuticos. El análisis estadístico se realizó con paquete estadístico STATA (versión 9.0). Resultados: Se le ofreció el servicio a una población de 904 personas, de las que 897 participaron; de estas últimas, 436 presentaron valores alterados de las patologías incluidas en el estudio. Para evaluar el efecto de la intervención farmacéutica sobre la efectividad de los tratamientos farmacológicos, se observó que en el grupo con hipertrigliceridemia, hipercolesterolemia y diabetes mellitus tipo 2 se produjo una disminución estadísticamente significativa de las concentraciones séricas de triglicéridos, colesterol y glucosa (p <0,001), respectivamente. De igual manera, se observó una reducción de la presión arterial diastólica y sistólica (p <0,001) después de la intervención. La evaluación clínica de los pacientes al final del tratamiento que incluyó servicios farmacéuticos fue en sentido favorable, ya que el 82,56% de la población de estudio refirió valores controlados dentro de las patologías de estudio y valores estadísticamente significativos (p <0,001). Los resultados negativos asociados a la medicación identificados fueron del tipo inefectividad cuantitativa, y se detectaron 14 reacciones adversas a medicamentos tipo A. Conclusiones: La atención farmacéutica es una estrategia idónea para actuar en el complejo proceso de generación y protección de la salud en comunidades vulnerables, como son las rurales con poblaciones con enfermedades crónico-degenerativas

Gauge and Scheme Dependence of Mixing Matrix Renormalization

We revisit the issue of mixing matrix renormalization in theories that include Dirac or Majorana fermions. We show how a gauge-variant on-shell renormalized mixing matrix can be related to a manifestly gauge-independent one within a generalized ${\bar {\rm MS}}$ scheme of renormalization. This scheme-dependent relation is a consequence of the fact that in any scheme of renormalization, the gauge-dependent part of the mixing-matrix counterterm is ultra-violet safe and has a pure dispersive form. Employing the unitarity properties of the theory, we can successfully utilize the afore-mentioned scheme-dependent relation to preserve basic global or local symmetries of the bare Lagrangian through the entire process of renormalization. As an immediate application of our study, we derive the gauge-independent renormalization-group equations of mixing matrices in a minimal extension of the Standard Model with isosinglet neutrinos.Comment: 31 pages, LaTeX, uses axodraw.st

Search for a W' boson decaying to a bottom quark and a top quark in pp collisions at sqrt(s) = 7 TeV

Results are presented from a search for a W' boson using a dataset corresponding to 5.0 inverse femtobarns of integrated luminosity collected during 2011 by the CMS experiment at the LHC in pp collisions at sqrt(s)=7 TeV. The W' boson is modeled as a heavy W boson, but different scenarios for the couplings to fermions are considered, involving both left-handed and right-handed chiral projections of the fermions, as well as an arbitrary mixture of the two. The search is performed in the decay channel W' to t b, leading to a final state signature with a single lepton (e, mu), missing transverse energy, and jets, at least one of which is tagged as a b-jet. A W' boson that couples to fermions with the same coupling constant as the W, but to the right-handed rather than left-handed chiral projections, is excluded for masses below 1.85 TeV at the 95% confidence level. For the first time using LHC data, constraints on the W' gauge coupling for a set of left- and right-handed coupling combinations have been placed. These results represent a significant improvement over previously published limits.Comment: Submitted to Physics Letters B. Replaced with version publishe

Search for the standard model Higgs boson decaying into two photons in pp collisions at sqrt(s)=7 TeV

A search for a Higgs boson decaying into two photons is described. The analysis is performed using a dataset recorded by the CMS experiment at the LHC from pp collisions at a centre-of-mass energy of 7 TeV, which corresponds to an integrated luminosity of 4.8 inverse femtobarns. Limits are set on the cross section of the standard model Higgs boson decaying to two photons. The expected exclusion limit at 95% confidence level is between 1.4 and 2.4 times the standard model cross section in the mass range between 110 and 150 GeV. The analysis of the data excludes, at 95% confidence level, the standard model Higgs boson decaying into two photons in the mass range 128 to 132 GeV. The largest excess of events above the expected standard model background is observed for a Higgs boson mass hypothesis of 124 GeV with a local significance of 3.1 sigma. The global significance of observing an excess with a local significance greater than 3.1 sigma anywhere in the search range 110-150 GeV is estimated to be 1.8 sigma. More data are required to ascertain the origin of this excess.Comment: Submitted to Physics Letters

Measurement of the Lambda(b) cross section and the anti-Lambda(b) to Lambda(b) ratio with Lambda(b) to J/Psi Lambda decays in pp collisions at sqrt(s) = 7 TeV

The Lambda(b) differential production cross section and the cross section ratio anti-Lambda(b)/Lambda(b) are measured as functions of transverse momentum pt(Lambda(b)) and rapidity abs(y(Lambda(b))) in pp collisions at sqrt(s) = 7 TeV using data collected by the CMS experiment at the LHC. The measurements are based on Lambda(b) decays reconstructed in the exclusive final state J/Psi Lambda, with the subsequent decays J/Psi to an opposite-sign muon pair and Lambda to proton pion, using a data sample corresponding to an integrated luminosity of 1.9 inverse femtobarns. The product of the cross section times the branching ratio for Lambda(b) to J/Psi Lambda versus pt(Lambda(b)) falls faster than that of b mesons. The measured value of the cross section times the branching ratio for pt(Lambda(b)) > 10 GeV and abs(y(Lambda(b))) < 2.0 is 1.06 +/- 0.06 +/- 0.12 nb, and the integrated cross section ratio for anti-Lambda(b)/Lambda(b) is 1.02 +/- 0.07 +/- 0.09, where the uncertainties are statistical and systematic, respectively.Comment: Submitted to Physics Letters

Search for new physics in events with opposite-sign leptons, jets, and missing transverse energy in pp collisions at sqrt(s) = 7 TeV

A search is presented for physics beyond the standard model (BSM) in final states with a pair of opposite-sign isolated leptons accompanied by jets and missing transverse energy. The search uses LHC data recorded at a center-of-mass energy sqrt(s) = 7 TeV with the CMS detector, corresponding to an integrated luminosity of approximately 5 inverse femtobarns. Two complementary search strategies are employed. The first probes models with a specific dilepton production mechanism that leads to a characteristic kinematic edge in the dilepton mass distribution. The second strategy probes models of dilepton production with heavy, colored objects that decay to final states including invisible particles, leading to very large hadronic activity and missing transverse energy. No evidence for an event yield in excess of the standard model expectations is found. Upper limits on the BSM contributions to the signal regions are deduced from the results, which are used to exclude a region of the parameter space of the constrained minimal supersymmetric extension of the standard model. Additional information related to detector efficiencies and response is provided to allow testing specific models of BSM physics not considered in this paper.Comment: Replaced with published version. Added journal reference and DO

Measurement of isolated photon production in pp and PbPb collisions at sqrt(sNN) = 2.76 TeV

Isolated photon production is measured in proton-proton and lead-lead collisions at nucleon-nucleon centre-of-mass energies of 2.76 TeV in the pseudorapidity range |eta|<1.44 and transverse energies ET between 20 and 80 GeV with the CMS detector at the LHC. The measured ET spectra are found to be in good agreement with next-to-leading-order perturbative QCD predictions. The ratio of PbPb to pp isolated photon ET-differential yields, scaled by the number of incoherent nucleon-nucleon collisions, is consistent with unity for all PbPb reaction centralities.Comment: Submitted to Physics Letters

Measurement of the mass difference between top quark and antiquark in pp collisions at root s=8 TeV

Peer reviewe

Measurements of the t(t)Overbar charge asymmetry using the dilepton decay channel in pp collisions at root s=7 TeV

The tt¯ charge asymmetry in proton-proton collisions at s&#8730; = 7 TeV is measured using the dilepton decay channel (ee, e &#956; , or &#956;&#956; ). The data correspond to a total integrated luminosity of 5.0 fb &#8722;1 , collected by the CMS experiment at the LHC. The tt and lepton charge asymmetries, defined as the differences in absolute values of the rapidities between the reconstructed top quarks and antiquarks and of the pseudorapidities between the positive and negative leptons, respectively, are measured to be A C = &#8722;0 . 010 ± 0 . 017 (stat . ) ± 0 . 008 (syst . ) and AlepC = 0 . 009 ± 0 . 010 (stat . ) ± 0 . 006 (syst . ). The lepton charge asymmetry is also measured as a function of the invariant mass, rapidity, and transverse momentum of the tt¯ system. All measurements are consistent with the expectations of the standard model