Kreuzungszucht beim Milchrind - ökonomische Bewertung

Das Projekt gibt einen Literaturüberblick zu Rassenkreuzungen beim Milchrind, wertet eine Befragung sächsischer Betriebe, die Kreuzungsverfahren anwenden, aus und beschreibt die Methodik eines im Rahmen des Projektes angepassten ökonomischen Kalkulationsschemas. Anhand beispielhafter Berechnungen nach dem Prinzip der Leistungs- und Kostenrechnung lassen sich für die Rassenkreuzungen Holstein-Friesian mit Fleckvieh, Braunvieh und skandinavischem Rotvieh vergleichende ökonomische Kalkulationen, auch im Vergleich zu den Ausgangsrassen, durchführen. Das Kalkulationsmodell ermöglicht eine Vielzahl von Variantenrechnungen. Es steht als Excel-Anwendung auf Anfrage allen interessierten Praktikern zu Verfügung

Патентная система как метод налогового регулирования малого бизнеса

В современной рыночной экономике малый бизнес играет важную роль. Но существование малого бизнеса практически невозможно без активной поддержки со стороны государства, которая должна заключаться в разработке различных программ содействия малому бизнесу, в том числе формирование льготной налоговой политики, направленной на стимулирование его развития. В настоящей работе дана характеристика новой патентной системы налогообложения, введенной в действие с 2013 г., проанализированы ее основные отличия от действующих специальных налоговых режимов. Сделан вывод о том, что новая патентная система как метод налогового регулирования малого бизнеса требует существенной доработки

Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study

This study was supported by grants from the German Heart Foundation (Deutsche Stiftung für Herzforschung) and from the Else Kröner-Fresenius-Stiftung, Germany

From the paddock to the stream : unravelling the nitrogen flowpaths in a New Zealand dairying catchment

The Toenepi catchment (15 km2) is dominated by dairying, and ranges in elevation from 40 to 130m above sea level (ASL). Most of the catchment is flat land, with some rolling and steep land occurring on the boundaries. Annual rainfall is 1132 mm and mean annual temperature is 13.3°C. Well-drained Allophanic soils dominate in the catchment in close association with granular soils of moderate permeability. Poorly drained Gley soils occur in the lowest areas adjacent to the stream and require artificial drainage. The average stocking rate is 3.0 cows ha–1, which graze all year. The catchment export of total nitrogen through the stream had been calculated in an earlier project as 35 kg ha–1 yr–1. The median total nitrogen concentration in the stream was 3 mg L–1 (1995/97). To better understand nitrogen flowpaths, we initially installed groundwater monitoring transects in seven subcatchments, which reflected the major site and landuse conditions. Monthly sampling indicated that the concentrations of inorganic nitrogen in the shallow groundwater were generally well below the concentrations measured in the stream. This result would not support the hypothesis that the majority of the nitrate in the stream is derived from groundwater. Monitoring of the nitrogen concentrations in drains indicated that artificial drainage may be a major conduit for nitrogen into the stream. Artificial drains bypass the deeper subsoil and riparian zones where denitrification is likely to occur. A mathematical groundwater discharge model is used to quantify the proportion of streamflow that can be explained by groundwater discharge in contrast to near-surface flowpaths (surface runoff, artificial drainage). Understanding the pathways through which nitrogen enters Toenepi Stream is considered a prerequisite for the development of the most effective and efficient measures to reduce the N contamination of the stream

Macrophages inhibit Coxiella burnetii by the ACOD1 ‐itaconate pathway for containment of Q fever

Infection with the intracellular bacterium Coxiella (C.) burnetii can cause chronic Q fever with severe complications and limited treatment options. Here, we identify the enzyme cis-aconitate decarboxylase 1 (ACOD1 or IRG1) and its product itaconate as protective host immune pathway in Q fever. Infection of mice with C. burnetii induced expression of several anti-microbial candidate genes, including Acod1. In macrophages, Acod1 was essential for restricting C. burnetii replication, while other antimicrobial pathways were dispensable. Intratracheal or intraperitoneal infection of Acod1-/- mice caused increased C. burnetii burden, weight loss and stronger inflammatory gene expression. Exogenously added itaconate restored pathogen control in Acod1-/- mouse macrophages and blocked replication in human macrophages. In axenic cultures, itaconate directly inhibited growth of C. burnetii. Finally, treatment of infected Acod1-/- mice with itaconate efficiently reduced the tissue pathogen load. Thus, ACOD1-derived itaconate is a key factor in the macrophage-mediated defense against C. burnetii and may be exploited for novel therapeutic approaches in chronic Q fever

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Search for narrow resonances in dilepton mass spectra in proton-proton collisions at root s=13 TeV and combination with 8 TeV data

Peer reviewe

Search for top squark pair production in pp collisions at root s=13 TeV using single lepton events

Peer reviewe

Search for supersymmetry in events with photons and missing transverse energy in pp collisions at 13 TeV

Peer reviewe