11 research outputs found
Ausgewogene Life-Balance durch erfolgreiches Zielmanagement
- Author
- Publication venue
- Universitätsbibliothek Bielefeld
- Publication date
- 01/01/2013
- Field of study
Chong CS. Ausgewogene Life-Balance durch erfolgreiches Zielmanagement. Bielefeld: Universitätsbibliothek Bielefeld; 2013.Im ersten Teil dieser Arbeit wurde ein umfangreiches Zielmodell des Subjektiven Wohlbefindens (SWB) formuliert, welches eine Erweiterung des telenomischen Modells des SWB von Brunstein und Maier (2002) darstellt. Dabei wurden bisherige Forschungsergebnisse berücksichtigt und neue theoretische Annahmen integriert. Das neue Modell umfasste neben bereits bekannten Faktoren (Zielbindung, Realisierbarkeit, Zieleffektivität) auch Zielkonflikte und Persönlichkeitseigenschaften. Weiterhin stellte die Arbeitszufriedenheit eine zentrale abhängige Variable dar, deren Auswirkungen auf die Unternehmensbindung und Kündigungsabsicht überprüft wurden. Eine Online-Studie, an der insgesamt 267 Personen teilnahmen, lieferte die Datenbasis für eine umfangreiche Modellprüfung. Der Großteil der Modellannahmen konnte mithilfe eines Strukturgleichungsmodells empirisch belegt werden. Die Ergebnisse wurden vor allem in Hinblick auf die unterschiedliche Wichtigkeit eines Ziels interpretiert.
Ausgehend von zwei Interventionsprogrammen zur Steigerung der Zielerreichung und des SWBs (Dargel, 2005; Spaniol, 2007) wurde im zweiten Teil dieser Arbeit eine Trainingsweiterentwicklung vorgenommen. Dabei handelte es sich um ein achtstündiges interaktives Workshop-Konzept, welches speziell auf den Kontext der multiplen Zielverfolgung zugeschnitten war, indem es Ziele aus vier unterschiedlichen Lebensbereichen (Arbeit & Leistung, Familie & Kontakte, Körper & Gesundheit, Sinn & Kultur) zum Gegenstand der Analysen machte. Das Training bestand aus fünf Modulen, welche ausgehend von einer ausführlichen Definition der vier Ziele sowie einer intensiven Reflexion dieser über deren Vergleich und Priorisierung bis hin zur schrittweisen Planung jedes einzelnen Ziels die Zieleffektivität der Teilnehmer erhöhen sollte. Im Rahmen einer quasiexperimentellen Studie wurde eine Trainingsgruppe (N=23) mit einer untrainierten Kontrollgruppe (N=23) verglichen. Die Befunde legten nahe, dass das Zielerreichungstraining das Bewusstsein für den Umgang mit Zielen gefördert und ein effektiveres Zielstrebungsverhalten unterstützt hat
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A.
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O.
- Ademuyiwa Adesoji O.
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O.
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W.
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A.
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
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- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F.
- Amandito Radhian
- Amandito Radhian
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- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
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- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
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- Andreotti Dario
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- Ang Yun Lin
- Angelieri Daniele
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- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
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- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
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- Aruldas Neerav
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Ashour Ahmad
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- Assal Abdelrahman
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- Ata Ahmed
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- Augestad Knut Magne
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- Awadallah Salwa
- Ayandipo Omobolaji
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- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G.
- Azzie Georges
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- Chu Kathryn
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- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Corral Moreno Sara
- Correa Juan Camilo
- Corro-Diaz Samantha
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- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Craus-Miguel Andrea
- Cullen Fraser
- Curletti Gianluca
- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S.
- Dabboor Majd
- Dabbour Kareem
- Dagoe Enoch
- Dahy Ahmed
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- Dakubo Jonathan
- Dalli Jeffrey
- Dally Charles
- Dambrauskas Zilvinas
- Daniyan Muhammad
- Danys Donatas
- Dao Weihei
- Dar Wasim
- Dardenne Sabrina
- Darwish Abdelrhman K. Z.
- Dasari Mohini
- Dashnyam Enkhbat
- Dassah Victor
- Datta Uttaran
- Davies Rachel
- Davor Anthony
- Dawood Khaled
- Dayie Makafui
- De Boni Davide
- De Franciscis Silvia
- De Luca Emilia
- De Marco Paolino
- Deal Rebecca
- Deane Chelsea
- Debrah Sam
- Dedekind Britta
- Dedey Florence
- Del Basso Celeste
- del Pilar Paucar Arazzelly
- Delforge Xavier
- Dell Angela
- Denakpo Max
- Denewar Adel
- Depalma Norma
- Der Yishan
- Deutschmann Peter
- Dhillon Dharminder
- Di Martino Natale
- Di Saverio Salomone
- Diaconescu Bogdan
- Diaz Vico Tamara
- Diaz Zorrilla Carmina
- Diaz-Jover Paula
- Dick Lachlan
- Dijan Emilio
- Dimech Thea
- Din Farhat
- Dindyal Shiva
- Dione Parreno-Sacdalan Marie
- Dissanayake Tharindra
- Djivoh Fernande
- Domini Edgar
- Donnelly Philippa
- Dorani Radin Mohd Nurrahman Radin
- Dorisme Asnel
- Dossou Francis
- Dousset Bertrand
- Dragatas Deividas
- Drake Thomas M.
- Drake Thomas M.
- Drungilas Mantas
- du Plooy Flip
- Du Toit Frederick
- Duane Therese
- Duinhouwer Lucia
- Dulskas Audrius
- Ebidy Mai
- Ebidy Mai Mohamed
- Eid Mostafa Mahmoud
- El Dahab Ali Abo
- El Gendy Noran Halim
- El Halawany Mohamed
- El Jamassi Alaa
- El Kashash Ahmed
- El Sayed Islam Magdy
- El-Dien Khalid Salah
- El-Din Reham Alaa
- El-Din Shahinaz Alaa
- El-Gizawy Esraa
- El-Sagheer Nada
- El-Sawy Aya
- El-Sehily Ahmed
- El-Taher Esraa
- Elashry Rehab
- Elazab Alaa
- Elbanby Esraa Samir
- Elbe Peter
- Elbisomy Khaled Hesham
- Eldafrawy Mahmoud
- Eldeeb Ahmed Zaki
- Eldeen Esraa Alm
- Eldin Mostafa Ahmed Bahaa
- Elebute Olumide
- Elfarargy Arwa
- Elfeki Hossam
- Elfiky Mahmoud
- Elfouly Nesma
- Elfouly Yasmin
- Elgendy Alyaa Halim
- Elgheriany Mohammed
- Elhadad Alaa
- Elhadary Nourhan Medhat
- Elhadry Shady
- Elhalawany Esraa
- Elhamouly Sara
- Elhelbawy Mohamed Salah
- Elhendawy Abdelaziz
- Elhoseny Ghada
- Elhusseiny Ahmed Abd Elmoen
- Elkholy Shimaa Said
- Ellison Quinn
- Elmashala Amjad
- Elmasry Maha
- Elmihy Sohaila
- Elnagar Ahmedglal
- Elnajjar Mahmoud A.
- Elrazek Aly Abd
- Elsabbagh Nourhan
- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
- Elzahed Nada
- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
- English William
- Esam Abeer
- Escalante Salas Marilia Del Carmen
- Espin-Basany Eloy
- Espinoza Fernando
- Essam A. A.
- Essam Ahmed
- Essam Mahitab
- Essoun Samuel
- Esteban Enrique
- Estee Mahnuma Mahfuz
- Etchill Eric
- Etienne Sara
- Etwire Victor
- Evajelista Cicilia Viany
- Evans David
- Evans Elizabeth
- Ezzat Eslam
- Ezzat Tarek
- Faboya Omolara
- Fahim Marwan
- Fairfield Cameron
- Falaschi Federica
- Falco Nicolo
- Falzon Malcolm
- Farag Ahmed
- Farag Sameh
- Farahat Mahitab Morsy
- Fares Mohamed
- Farhan-Alanie Muhamed M. H.
- Farhangmehr Neda
- Farouk Sara Amr Mohamed
- Farrugia Alexia
- Farrugia Alexia
- Faruq Amreen
- Fathy Aya Mohamed
- Fatuga Adedeji
- Faturoti Olubukola
- Favero Alessandro
- Feidantsis Thomas
- Fergany Alaa
- Fergusson Stuart J.
- Fergusson Stuart J.
- Fermani Claudio Gabriel
- Fernandes Cristina
- Fernandez Carmen
- Fernandez-Vega Laura
- Ferousis Christoforos
- Ferrero Esther
- Filatau Aliaksandr
- Firdouse Mohammed
- Firdouse Mohammed
- Firwana Aya
- Fitsum Agazi
- Fitzgerald J. Edward
- Fitzgerald J. Edward
- Florez Farfan Erick Samuel
- Foco Maurizio
- Fok Chi Ying Jacquelyn
- Fontana Tommaso
- Foo Chi Chung
- Forlin Louise
- Fouad Dina
- Fourcade Laurent
- Francisco Roxas Manuel
- Franco Helena
- Francois Poddevin
- Francone Elisa
- Frey Daniel
- Fuentes-Rivera Lorena
- Gaafar Shireen
- Gaarder Tina
- Gad Ahmed
- Gad Mariam O.
- Gadelkarim Mohamed
- Gado Ammar
- Gaizauskas Vytautas
- Gala Tanzeela
- Gala Tanzeela
- Galiqi Gezim
- Galleano Raffaele
- Gallo Gaetano
- Gamal Dina
- Gamal Esraa
- Gamal Heba
- Gamal Shimaa
- Gamil Doaa
- Gan Cheewei
- Gan Yiing Yee
- Gani Mohammed Akil
- Garcia Bernardo Carmen
- Garcia Septiem Javier
- Garcia-Florez Luis
- Gash Katherine
- Gash Katherine
- Gastaldi Pauline
- Gaujoux Sebastien
- Gavagna Laura
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- Gemenetzis Georgios
- Germanos Stylianos
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- Geuoshy Abdelrahman
- Ghaben Ahed
- Ghanem Ahmed
- Ghanem Sara
- Ghannam Mohammad
- Ghoneim Omar
- Giardino Francesco Ruben
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- Gonzales Montejo Maria Soledad
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- Grella Maria Giovanna
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- Grobler D. C.
- Grosos Celine
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- Guner Ali
- Gupta Ashish
- Guzman Duenas Carolina
- Gyamfi Frank Enoch
- Gyedu Adam
- Habeeb Olufemi
- Haddad Nadeem
- Hafez Mohamed
- Hafez Sarah
- Haffreingue Aurore
- Hagan Richmond
- Haines Morgan
- Hajeh Haidar
- Halhouli Oday
- Halhouli Oday
- Halicioglu Ilkay
- Hall Elisabeth
- Haloho Andreass
- Hamarshi Aseel
- Hamasaki Hamaguchi Jose Luis
- Hamdan Ayah
- Hamdan Marwa
- Hamed Mohamed Fouad
- Hamill Daniel
- Hammad Aya
- Hampton Mark Ian
- Hamsho Ward
- Hanoun Sakhaa
- Hantour Usama
- Hany Ethar
- Haque Muhtarima
- Har Prisca A. L.
- Haraux Elodie
- Harrison Ewen M.
- Harrison Ewen M.
- Harrison Ewen M.
- Hartford Leila
- Harvey Neil
- Hasan Ahmad
- Hasan Doaa
- Hasanah Afifatun
- Hasanain Doaa
- Hascoet Juliette
- Hashad Eman
- Hashim Abdullah
- Haslegrave Aidan
- Hassaan Amr
- Hassaan Ayat
- Hassan Ahmed Tarek Abdelbaset
- Hassan Ihab
- Hassan Osama Mokhtar Mohamed
- Hassanain Mazen
- Hassanein Adel B.
- Heard Rachel
- Hegazy Eman Magdy
- Helene Francois-Coridon
- Helguero-Santin Luis M.
- Hemmila Mark
- Heng Hian Ee
- Henric Nicolas
- Henry Fitjerald
- Henshall David Ewart
- Herebat Azher
- Herikstad Ragnar
- Herrera Cruz Danilo
- Herrera Matta Juan Jaime
- Herrod Philip
- Hervieux Erik
- Hesham Omar
- Hilal Karim
- Hjertberg Maria
- Hmila Sophian
- Ho Adrienne
- Hodonou Fred
- Holte Silje
- Homeida Anmar
- Hossameldin Amr
- Hrora Abdelmalek
- Hunter Kristina
- Husseiny Reem
- Iacono Calogero
- Iannone Immacolata
- Ibraheem Aya AbdelFatah
- Ibrahem Ahmad Aboelkassem
- Ibrahim Ahmed Mohamed
- Ibrahim Amal
- Ibrahim Arij
- Ibrahim Arwa
- Ibrahim Eman
- Ibrahim Eman Mohamed
- Ibrahim Khaled
- Ibrahim Mohamed
- Idress Tasneem
- Idris Faisal
- Iftekhar Farhana
- Iftikhar Zainab
- Ignatavicius Povilas
- Ihediwa George
- Imoro Osman
- Ingabire J. C. Allen
- Ingabire J. C. Allen
- Ioannidis Orestis
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- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- Elsevier
- Publication date
- 01/06/2003
- Field of study
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Andress Cedar
- Andriola Valeria
- Ang Yun Lin
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Ansaloni Luca
- Ansaloni Luca
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aquilino Fabrizio
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Arcudi Claudio
- Armellini Andrea
- Arnaud Alexis
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
- Arthur Tom
- Aruldas Neerav
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Ashour Ahmad
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Attia Attia
- Augestad Knut Magne
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awadallah Salwa
- Ayandipo Omobolaji
- Aydin Mehmet Can
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badicel Maria
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin Mohamed
- Bahar Suraya
- Baillie Katie
- Baki Bahadir Emre
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Balducci Genoveffa
- Ballouhey Quentin
- Balmaceda Ruben
- Balmaceda Ruben
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamford Rebecca
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandi Ashwath
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baquero Suarez Alibeth Andres
- Baraka Heba
- Barendegere Venerand
- Barkolias Christos
- Barmayehvar Behrad
- Barnabas Gandau Naa
- Barrios Emmanuel
- Basilico Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Stefano MM
- Bayram Sefa
- Beamon Mieshia
- Bedada Alemayehu Ginbo
- BediakoBowan Antoinette
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleno Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bhangu Aneel
- Bhangu Aneel
- Bhangu Anna
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Bin Adnan Ahmad
- Bin Hasnan Muhammad
- Bin Ismail Mohamad Jeffrey
- Birindelli Arianna
- Bisset Carly
- Bjorklund Ida
- Blacker Sarah
- Blackwell James
- Blanco Ruth
- Blanco-Colino Ruth
- Blencowe Natalie
- Bliksoen Marte
- Bluelle Rafael
- Bocchetti Tommaso
- Bode Chris
- Bodur Selim
- Boggon Adam
- Bonavia Karl
- Bonavina Luigi
- Bond-Smith Giles
- Bondin John
- Bondurri Andrea
- Boni Silvia
- Bonney William
- Borda-Luque Giuliano
- Borg Elaine
- Borg Elaine
- Bortolasi Luca
- Bottini Corrado
- Bougard Heather
- Boukhal Khaoula
- Bowabsak Alaa
- Bowling Kirk
- Bradulskis Saulius
- Bratu Matei
- Bratu Matei Razvan
- Breaud Jean
- Breistrand Michaela
- Breslin Ryan
- Brincat Svetlana Doris
- Broch Aline
- Brunoni Beatrice
- Bsisu Isam
- Bucci Luigi
- Buisson Philippe
- Bunting David
- Burger Sule
- Burmistrovas Andrius
- Bustangi Nasir
- Bustangi Nasir
- Butt Muhammad Talha
- Cakaloglu Haluk Cem
- Caliman Celeste
- Callan Rory
- Camilleri Georgette Marie
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canta Calua Alexander
- Capito Carmen
- Carabott Kurt
- Carmela Lapitan Marie
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
- Cassar Kristina
- Catani Marco
- Cautiero Roberto
- Caydiid Hanaan
- Cecilia Tolg
- Celik Saban
- Cengiz Turgut Bora
- Cengiz Yucel
- Cengiz Yucel
- Cevik Muazzez
- Chabok Abbas
- Chai Chu-Ann
- Chai Feng Yih
- Chan Luke
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Kar Yan
- Chen Tzu-Ling
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chibuye Chali
- Chiesa Deborah
- Chilton Gareth
- Chin Pui Xin
- Chin Ye Ru
- Chiu Seehui
- Choi Philip
- Chong Choon Seng
- Chong Hoong-Yin
- Choudhry Asad
- Chow Crystal Yern Nee
- Chowdhury Debkumar
- Chu Kathryn
- Chung Kuet Jun
- Chungui Bravo Jorge Armando
- Ciccioli Eleonora
- Ciubotaru Cezar
- Claire Raquillet
- Clarissa Audrey
- Clegg-Lampety Joe-Nat
- Clegg-Lamptey Joe-Nat
- Clerico Giuseppe
- Coccolini Federico
- Coccolini Federico
- Cocorullo Gianfranco
- Cohen Fraser
- Cole Simon
- Coletta Diego
- Coletti Massimo
- Collaborative GlobalSurg
- Cona Camilla
- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C
- Connor Katie
- Contreras Elisa
- Coompson Christian Lari
- Corbellini Carlo
- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Corral Moreno Sara
- Correa Juan Camilo
- Corro-Diaz Samantha
- Costa Cecilia
- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Craus-Miguel Andrea
- Cullen Fraser
- Curletti Gianluca
- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S
- Dabboor Majd
- Dabbour Kareem
- Dagoe Enoch
- Dahy Ahmed
- Dainius Edvinas
- Dakubo Jonathan
- Dalli Jeffrey
- Dally Charles
- Dambrauskas Zilvinas
- Daniyan Muhammad
- Danys Donatas
- Dao Weihei
- Dar Wasim
- Dardenne Sabrina
- Darwish Abdelrhman KZ
- Dasari Mohini
- Dashnyam Enkhbat
- Dassah Victor
- Datta Uttaran
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- Davor Anthony
- Dawood Khaled
- Dayie Makafui
- De Boni Davide
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- De Luca Emilia
- De Marco Paolino
- Deal Rebecca
- Deane Chelsea
- Debrah Sam
- Dedekind Britta
- Dedey Florence
- Del Basso Celeste
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- Delforge Xavier
- Dell Angela
- Denakpo Max
- Denewar Adel
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- Der Yishan
- Deutschmann Peter
- Dhillon Dharminder
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- Di Saverio Salomone
- Diaconescu Bogdan
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- Diaz Zorrilla Carmina
- Diaz-Jover Paula
- Dick Lachlan
- Dijan Emilio
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- Din Farhat
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- Dissanayake Tharindra
- Djivoh Fernande
- Domini Edgar
- Donnelly Philippa
- Dorani Radin Mohd Nurrahman Radin
- Dorisme Asnel
- Dossou Francis
- Dousset Bertrand
- Dragatas Deividas
- Drake Thomas M
- Drake Thomas M
- Drungilas Mantas
- du Plooy Flip
- Du Toit Frederick
- Duane Therese
- Duinhouwer Lucia
- Dulskas Audrius
- Ebidy Mai
- Ebidy Mai Mohamed
- Eid Mostafa Mahmoud
- El Dahab Ali Abo
- El Gendy Noran Halim
- El Halawany Mohamed
- El Jamassi Alaa
- El Kashash Ahmed
- El Sayed Islam Magdy
- El-Dien Khalid Salah
- El-Din Reham Alaa
- El-Din Shahinaz Alaa
- El-Gizawy Esraa
- El-Sagheer Nada
- El-Sawy Aya
- El-Sehily Ahmed
- El-Taher Esraa
- Elashry Rehab
- Elazab Alaa
- Elbanby Esraa Samir
- Elbe Peter
- Elbisomy Khaled Hesham
- Eldafrawy Mahmoud
- Eldeeb Ahmed Zaki
- Eldeen Esraa Alm
- Eldin Mostafa Ahmed Bahaa
- Elebute Olumide
- Elfarargy Arwa
- Elfeki Hossam
- Elfiky Mahmoud
- Elfouly Nesma
- Elfouly Yasmin
- Elgendy Alyaa Halim
- Elgheriany Mohammed
- Elhadad Alaa
- Elhadary Nourhan Medhat
- Elhadry Shady
- Elhalawany Esraa
- Elhamouly Sara
- Elhelbawy Mohamed Salah
- Elhendawy Abdelaziz
- Elhoseny Ghada
- Elhusseiny Ahmed Abd Elmoen
- Elkholy Shimaa Said
- Ellison Quinn
- Elmashala Amjad
- Elmasry Maha
- Elmihy Sohaila
- Elnagar Ahmedglal
- Elnajjar Mahmoud A
- Elrazek Aly Abd
- Elsabbagh Nourhan
- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
- Elzahed Nada
- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
- English William
- Esam Abeer
- Escalante Salas Marilia Del Carmen
- Espin-Basany Eloy
- Espinoza Fernando
- Essam AA
- Essam Ahmed
- Essam Mahitab
- Essoun Samuel
- Esteban Enrique
- Estee Mahnuma Mahfuz
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- Etienne Sara
- Etwire Victor
- Evajelista Cicilia Viany
- Evans David
- Evans Elizabeth
- Ezzat Eslam
- Ezzat Tarek
- Faboya Omolara
- Fahim Marwan
- Fairfield Cameron
- Falaschi Federica
- Falco Nicolo
- Falzon Malcolm
- Farag Ahmed
- Farag Sameh
- Farahat Mahitab Morsy
- Fares Mohamed
- Farhan-Alanie Muhamed MH
- Farhangmehr Neda
- Farouk Sara Amr Mohamed
- Farrugia Alexia
- Farrugia Alexia
- Faruq Amreen
- Fathy Aya Mohamed
- Fatuga Adedeji
- Faturoti Olubukola
- Favero Alessandro
- Feidantsis Thomas
- Fergany Alaa
- Fergusson Stuart J
- Fergusson Stuart J
- Fermani Claudio Gabriel
- Fernandes Cristina
- Fernandez Carmen
- Fernandez-Vega Laura
- Ferousis Christoforos
- Ferrero Esther
- Filatau Aliaksandr
- Firdouse Mohammed
- Firdouse Mohammed
- Firwana Aya
- Fitsum Agazi
- Fitzgerald J Edward
- Fitzgerald J Edward
- Florez Farfan Erick Samuel
- Foco Maurizio
- Fok Chi Ying Jacquelyn
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- Foo Chi Chung
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- Fouad Dina
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- Francisco Roxas Manuel
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- Francois Poddevin
- Francone Elisa
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- Fuentes-Rivera Lorena
- Gaafar Shireen
- Gaarder Tina
- Gad Ahmed
- Gad Mariam O
- Gadelkarim Mohamed
- Gado Ammar
- Gaizauskas Vytautas
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- Gala Tanzeela
- Galiqi Gezim
- Galleano Raffaele
- Gallo Gaetano
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- Hamsho Ward
- Hanoun Sakhaa
- Hantour Usama
- Hany Ethar
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- Har Prisca AL
- Haraux Elodie
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- Harrison Ewen M
- Harrison Ewen M
- Hartford Leila
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- Van Straten Stephanie
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- Vartanoglu Talar
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
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- Velasquez Ricardo
- Venclauskas Linas
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- Venskutonis Donatas
- Venskutonis Donatas
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- Vergara Mejia Angelica Genoveva
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- Vida Lucian Corneliu
- Vilcinskas Mantas
- Villalobos Santiago
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- Wael Noha
- Wakefield Rebecca
- Waledziak Maciej
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- Walker Nathan
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- Walsh Michael
- Waqar Muhammad
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- Werder Gabriela
- Whitaker John
- White Rebecca
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Widmer Lukas Werner
- Wijayarathna LS
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Wilson Michael
- Wimalge PMSN
- Wogensen Fredrik
- Wolf Bernhard
- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world.
Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231.
Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001).
Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
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- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
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- Amin Amita G.
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- Homsi Deana K.
- Homsi Farah J.
- Honan Tracy
- Hood Leroy
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- Huang Wei
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- Hyde David
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- Idlebird Devincent G.
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- Imo Kelvin C.
- Inacio Nicole
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- Ishibashi Akiko
- Ishikawa Sabine K.
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- Jaeger Sara
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- Kettleborough Ross
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- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
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- Ludeman Thom
- Lui Annie
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
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- McMurray Kimberly L.
- McNinch Jenny
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- Meidi Patrick
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- Nakato Eriko
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- Nandkeshwar Richard
- Nankervis Colin E.
- Naranjo Cleo M.
- Nash William
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- Nazareth Lynne V.
- Neal Dearl D.
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- Nwokenkwo Stanley
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- O\u27Donovan Daniel
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- Okumura Reina
- Okwuonu Geoffrey O.
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- Olarnpunsagoon Alisa
- Olivas Jason
- Oliver Hayley
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- Olson Maynard V.
- Omotosho Bamidele
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- Ow David
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- Patel Dina
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- Patel Ritesh
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- Paul Shelia
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- Pennacchio Len A.
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- Percy Chantel
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- Perez Lesette M.
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- Pourrajabi Nima M.
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- Ridler Kerry
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- Sasaki Takashi
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- Saurin William
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- Saxman Eric
- Scarpelli Claude
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- Scherer Steven Edward
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- Sonnhammer Erik
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- Stege Justin T.
- Steingruber Helen
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- Zhang Xianglin
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- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Surgical site infection after gastrointestinal surgery in children : an international, multicentre, prospective cohort study
- Author
- A A Essam
- A B Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman Kz Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled AbdRabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B Hassanein
- Adel Denewer
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji O Ademuyiwa
- Adewale Adeniyi
- Adewale O Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd El-Sameea
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Alkhatib
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed Mohamed Ibrahim
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Said Badr
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M Kandil
- Ahmedglal Elnagar
- Ahmet Murat Pektaş
- Aia Mehdi
- Aida Suarez
- Aidan Haslegrave
- Ainhoa Costas-Chavarri
- Aized Raza Shahbaz
- Akin Olaolorun
- Akinlabi Ajao
- Al Faifi Jubran
- Ala Shamasneh
- Alaa Al-Buhaisi
- Alaa Bowabsak
- Alaa El Jamassi
- Alaa Elazab
- Alaa Elhadad
- Alaa Fergany
- Alaa Shaheen
- Alaba Adesina
- Alberto Miyar de León
- Alberto Realis Luc
- Alejandro Matheu
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alex Makupe
- Alex Reece-Smith
- Alexander Canta Calua
- Alexander Smedley
- Alexandra Gerosa
- Alexia Farrugia
- Alexis Arnaud
- Alexis Pierre Arnaud
- Alfio Alessandro Russo
- Alfredo Gulielmi
- Ali Ababneh
- Ali Abo El Dahab
- Ali Adam
- Ali Guner
- Ali Khan Niazi
- Ali Mussad
- Aliaksandr Filatau
- Aliang Latif
- Alibeth Andres Baquero Suarez
- Alice Murray
- Alina Robledo-Rabanal
- Aline Broch
- Alissa Gübeli
- Alistair Rocke
- Aliyu Ndajiwo
- Alphonse Zeta Mutabazi
- Alvaro Enrique Mendoza Beleño
- Alvin Ee Zhiun Cheah
- Aly Abd-Elrazek
- Aly Sanad
- Alyaa Halim Elgendy
- Amal Ibrahim
- Amany Eldosouky Mohammed
- Amar Kourdouli
- Amgad Al Meligy
- Amina Abdelhamid
- Aminah Hanum Haji Abdul Majid
- Aminu Mohammad
- Amir Ait Kaci
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- Amira Hassan Bekhet
- Amira Reda
- Amjad Abu Qumbos
- Amjad Elmashala
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- Amna Mamdouh Mohamed
- Amna Mohamed
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- Amr Hassaan
- Amr Hossameldin
- Amreen Faruq
- Amro Aglan
- Ana Lucia Contreras-Vergara
- Ana Maria Sandoval Barrantes
- Anahita Mansuri
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- Anass Majbar
- Anastasios Stefanopoulos
- Anders Thorell
- Andre L Mihaljevic
- Andre Navarro
- Andrea Armellini
- Andrea Belli
- Andrea Bondurri
- Andrea Craus-Miguel
- Andrea Natili
- Andrea Ruzzenente
- Andrea Simioni
- Andreass Haloho
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- Andrew Kirby
- Andrey Litvin
- Andrius Burmistrovas
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- Ankur Bhatnagar
- Anmar Homeida
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- Annalisa Lo Conte
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- Anwar Atiyeh
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- Rezaul Karim
- Ricardo Velasquez
- Richard Lilford
- Richard Opoku-Agyeman
- Richard Spence
- Richmond Hagan
- Riinu Ots
- Roaa Khan
- Robert Jaich
- Robert Karlo
- Robert Parker
- Robert Tyler
- Roberta Tutino
- Robertas Baltrunas
- Roberto Cautiero
- Roberto Klappenbach
- Roberto Peltrini
- Roberto Schiavone
- Robin Johnston
- Robinson Mas
- Roel Matos-Puig
- Rofida Elsemelawy
- Roger Schmid
- Rokas Rackauskas
- Rokayah Julaihi
- Roland Osuoji
- Romualdas Riauka
- Rory Callan
- Rosario Sacco
- Rose Khreishi
- Roy Quek
- Ruben Balmaceda
- Ruben Santiago Restrepo Giraldo
- Rubén Balmaceda
- Rudy Gunawan
- Rula Zaa'treh
- Ruta Mazelyte
- Ruth Blanco
- Ruth Blanco-Colino
- Ruth Scicluna
- Ryan Breslin
- Ryan Choon Kiat Tan
- Saban Celik
- Sabbir Karim
- Sabine Irtan
- Sabrina Asturias
- Sabrina Dardenne
- Sabry Mohy Eldeen Mahmoud
- Safia Ali
- Saged Elsherbiney
- Sahar Jaber
- Saiba Abdul-Latif
- Said Alyacoubi
- Sakhaa Hanoun
- Saleh Alqahtani
- Salma Magdy
- Salma Mansour
- Salomone Di Saverio
- Salwa Awadallah
- Salwa Khallaf
- Sam Debrah
- Sam Seisay
- Sam Shillito
- Samaa Mahmoud Al Attar
- Samah Afana
- Samantha Corro-Diaz
- Samar Abdelhady
- Samar Adel Ismail
- Samar Soliman
- Sameer Kushwaha
- Sameh Emile
- Sameh Farag
- Samson Olori
- Samuel Essoun
- Samuel Osei-Nketiah
- Samuel S Y Sii
- Sandip Kumar
- Sandra Ahlqvist
- Sandra Sanz
- Sandrine Kwizera
- Sandro Pasquali
- Sani Ali Samuel
- Sanjay Patel
- Sanju Sobnach
- Santiago Villalobos
- Sara Ahmed
- Sara Al-Saqqa
- Sara Amr Mohamed Farouk
- Sara Arafa
- Sara Corral Moreno
- Sara Elhamouly
- Sara Etienne
- Sara Ghanem
- Sara Mahmoud Abdel-Kader
- Sara Mamdouh Matter
- Sara Mohammed
- Sara W Al-Saqqa
- Sarah Benammi
- Sarah Blacker
- Sarah Hafez
- Sarah Rayne
- Sarah Sahel
- Saraibrahim Ahmed
- Saulius Bradulskis
- Saulius Mikalauskas
- Savino Occhionorelli
- Savva Pronin
- Sawsan Adel Awad
- Sayeda Nazmum Nahar
- Sayeeda Aktar Tori
- Scott D'Amours
- Sean Mizzi
- Sebastian King
- Sebastian Shu
- Sebastian Sierra
- Sebastien Gaujoux
- Sebestian Shu
- Seehui Chiu
- Sefa Bayram
- Selim Bodur
- Serena Manfreda
- Serge Kapenda Tshisola
- Sergio Ribaldi
- Servet Rustu Karahan
- Servio Tulio Torres Rodriguez
- Shadid Al Amin
- Shadid Alamin
- Shady Elhadry
- Shady Mahmoud
- Shahadatul Shaharuddin
- Shahinaz Alaa El-Din
- Shahinaz Alaael-Dein
- Shahrukh Mirza
- Shalon Guevara Torres
- Shamsudeen Aliyu
- Sharad Karandikar
- Shareef Mahdi
- Sharon Koh
- Shaun Oram
- Shayanthan Nanthakumaran
- Shaza Rabie Mohamed
- Sherif Tariq
- Shimaa Gamal
- Shimaa Said Elkholy
- Shireen Gaafar
- Shiva Dindyal
- Shivanchan Rajmohan
- Shivun Khosla
- Shpetim Ymeri
- Shu Ning Kong
- Shuang Yi Teo
- Shujing Jane Lim
- Shyang Yee Lim
- Sibongile Ruth Ndlovu
- Silje Holte
- Silke Mahanty
- Silvia Basilicò
- Silvia Boni
- Silvia De Franciscis
- Simon Cole
- Simon Paterson-Brown
- Simon Stock
- Simona Kasputyte
- Simone Conci
- Simone Sandler
- Simone Targa
- Sinem Yolcu
- Sir Young Yam
- Siti Mohd Desa Asilah
- Siti Nur Alia Kamarulzamil
- Sivesh K Kamarajah
- Sobhana Iftekhar Tani
- Soha Abushamleh
- Sohaila Elmihy
- Sondos Turkustani
- Sophian Hmila
- Spb Thalgaspitiya
- Stavros Parasyris
- Stefan Zammit
- Stefano Berti
- Stefano Giuliani
- Stefano Mm Basso
- Sten Saar
- Stephanie Hiu-Wai Kwok
- Stephanie Van Straten
- Stephen Kache
- Stephen Knight
- Stephen O'Neill
- Stephen Tabiri
- Steponas Petrikenas
- Stuart J Fergusson
- Styliani Parpoudi
- Stylianos Germanos
- Suhhuey Yap
- Sukrit Suresh
- Sule Burger
- Suleiman Baba
- Sunil Kumar
- Suraj Kadiwar
- Suraya Bahar
- Susan Aviles
- Susan McGarvie
- Susan Wndy Mathew
- Suzanne Kershaw
- Svetlana Doris Brincat
- Swapnil Roy
- Syed Abdul Wahhab Eusoffee Wan Ali
- Syed Asaat Ul Razi
- Sylvia Kamya
- Sylvie Mochet
- Syrine Rekhis
- T Ariani Widiastini
- Taha Yusufali
- Taher Al-Taher
- Taiwo Lawal
- Talar Vartanoglu
- Tamara Diaz Vico
- Tanzeela Gala
- Tara Grima
- Tarek Ezzat
- Tariq Alhammali
- Tasneem Idress
- Tasnia Hamid Kanta
- Tatsiana Shachykava
- Tebian Hassanein Ahmed Ali
- Tewodros Worku
- Thamer Nouh
- Thandinkosi Madiba
- Tharindra Dissanayake
- Thays Brunelli Pugliesi
- Thea Dimech
- Thelma Tembo
- Theodore Pezas
- Theodosios Theodosopoulos
- Therese Duane
- Thierry Alihonou
- Thomas Feidantsis
- Thomas Kidd
- Thomas M Drake
- Thomas Mann
- Thomas Olagboyega Olajide
- Thomas Pinkney
- Thomas Prudhomme
- Thomas Tetens Moe
- Tien Seng Bryan Lee
- Tina Gaarder
- Tobias Schuetz
- Todisoa Emmanuella Christina Tolotra
- Tolg Cecilia
- Tom Abbott
- Tom Arthur
- Tomas Abaliksta
- Tomas Jankus
- Tomas Poskus
- Tomas Poškus
- Tomas Urbonas
- Tommaso Bocchetti
- Tommaso Campagnaro
- Tommaso Fontana
- Toqa Khafagy
- Torhild Veen
- Tsz-Yan Katie Chan
- Tuan Nur'Azmah Tuan Mat
- Tunde Sholadoye
- Turgut Bora Cengiz
- Twc Mak
- Tyler Rouse
- Tzu-Ling Chen
- Uday Muddebihal
- Umar Muktar
- Umberto Tedeschi
- Umme Salma
- Usama Hantour
- Uttaran Datta
- Vahit Mutlu
- Valdemaras Jotautas
- Valeria Andriola
- Vanessa Msosa
- Vania Guglielmo
- Vania Silvestri
- Vasileios Kalles
- Vasiliki Soulou
- Vassilis Kalles
- Vedatcan Işler
- Veeranna Shatkar
- Venerand Barendegere
- Veronica Lazzari
- Vicky Jennings
- Victor Dassah
- Victor Etwire
- Victor Kong
- Victor Nwinee
- Vijaid Upadhyaya
- Viktorija Nevieraite
- Ville Sallinen
- Vincas Jonas Banaitis
- Virginia Jiménez Carneros
- Virginia Ramos Pérez
- Viviana Sollazzo
- Vladimir Khokha
- Volkan Ozben
- Vu Thanh Hien Le
- Vytautas Gaižauskas
- Vytautas Lipnickas
- Wadah Ali
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
- Waleed Thabet
- Walter Ruiz Panez
- Wan Nurul 'Ain Wan Mohd Nasir
- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Weihei Dao
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wiktor Rutkowski
- William Appeadu-Mensah
- William Bonney
- William English
- Willy Alcca Ticona
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda
- Ysabel Esthefany Alejos Bermúdez
- Yucel Cengiz
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ömer Faruk Toto
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Introduction Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings. Methods A multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI). Results Of 1159 children across 181 hospitals in 51 countries, 523 (45 center dot 1%) children were from high HDI, 397 (34 center dot 2%) from middle HDI and 239 (20 center dot 6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12 center dot 8% (51/397) in middle HDI and 24 center dot 7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI. Conclusion The odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.Peer reviewe
Braincharts for the human lifespan
- Author
- Adamson Chris
- Adler Sophie
- Alexopoulos George S
- Anagnostou Evdokia
- Anderson Kevin M
- Areces-Gonzalez Ariosky
- Astle Duncan E
- Auyeung Bonnie
- Ayub Muhammad
- Bae Jong Bin
- Ball Gareth
- Baron-Cohen Simon
- Beare Richard
- Bedford Saashi A
- Benegal Vivek
- Bethlehem Richard AI
- Beyer Frauke
- Biase Maria A Di
- Binette Alexa Pichet
- Blangero John
- Boardman James P
- Borzage Matthew
- Bosch-Bayard Jorge F
- Bourke Niall
- Cabez Manuel Blesa
- Calhoun Vince D
- Chakravarty Mallar M
- Chen Christina
- Chertavian Casey
- Chetelat Gael
- Chong Yap S
- Cole James H
- Corvin Aiden
- Courchesne Eric
- Crivello Fabrice
- Cropley Vanessa L
- Crosbie Jennifer
- Crossley Nicolas
- Delarue Marion
- Desrivieres Sylvane
- Devenyi Gabriel
- Dolan Ray
- Donald Kirsten A
- Donohoe Gary
- Dunlop Katharine
- Edwards Anthony D
- Elison Jed T
- Ellis Cameron T
- Elman Jeremy A
- Eyler Lisa
- Fair Damien A
- Fletcher Paul C
- Fonagy Peter
- Franz Carol E
- Galan-Garcia Lidice
- Gholipour Ali
- Giedd Jay
- Gilmore John H
- Glahn David C
- Goodyer Ian
- Grant PE
- Groenewold Nynke A
- Gunning Faith M
- Gur Raquel E
- Gur Ruben C
- Hammill Christopher F
- Hansson Oskar
- Hedden Trey
- Heinz Andreas
- Henson Richard
- Heuer Katja
- Hoare Jacqueline
- Holla Bharath
- Holmes Avram J
- Holt Rosie
- Huang Hao
- Im Kiho
- Ipser Jonathan
- Jack Clifford R
- Jackowski Andrea P
- Jia Tianye
- Johnson Keith A
- Jones David T
- Jones Peter B
- Kahn Rene
- Karlsson Hasse
- Karlsson Linnea
- Kawashima Ryuta
- Kelley Elizabeth A
- Kern Silke
- Kim KW
- Kitzbichler Manfred G
- Kremen William S
- Lalonde Francois
- Landeau Brigitte
- Lee Subin
- Lerch Jason
- Lewis John D
- Li Jiao
- Liao Wei
- Linares Deirel P
- Liston Conor
- Lombardo Michael V
- Lv Jinglei
- Lynch Charles
- Mallard Travis T
- Marcelis Machteld
- Markello Ross D
- Mazoyer Bernard
- McGuire Philip
- Meaney Michael J
- Mechelli Andrea
- Medic Nenad
- Misic Bratislav
- Morgan Sarah E
- Mothersill David
- Nigg Joel
- Ong Marcus QW
- Ortinau Cynthia
- Ossenkoppele Rik
- Ouyang Minhui
- Palaniyappan Lena
- Paly Leo
- Pan Pedro M
- Pantelis Christos
- Park Min Tae M
- Paus Tomas
- Pausova Zdenka
- Pierce Karen
- Qian Xing
- Qiu Anqi
- Qiu Jiang
- Raznahan Armin
- Rittman Timothy
- Rollins Caitlin K
- Romero-Garcia Rafael
- Ronan Lisa
- Rosenberg Monica D
- Rowitch David H
- Salum Giovanni A
- Satterthwaite Theodore D
- Schaare Lina
- Schachar Russell J
- Scholl Michael
- Schultz Aaron P
- Schumann Gunter
- Seidlitz Jakob
- Sharp David
- Vogel Jacob W
- White Simon R
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Over the past 25 years, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, there are no reference standards against which to anchor measures of individual differences in brain morphology, in contrast to growth charts for traits such as height and weight. Here, we built an interactive online resource (www.brainchart.io) to quantify individual differences in brain structure from any current or future magnetic resonance imaging (MRI) study, against models of expected age-related trends. With the goal of basing these on the largest and most inclusive dataset, we aggregated MRI data spanning 115 days post-conception through 100 postnatal years, totaling 122,123 scans from 100,071 individuals in over 100 studies across 6 continents. When quantified as centile scores relative to the reference models, individual differences show high validity with non-MRI brain growth estimates and high stability across longitudinal assessment. Centile scores helped identify previously unreported brain developmental milestones and demonstrated increased genetic heritability compared to non-centiled MRI phenotypes. Crucially for the study of brain disorders, centile scores provide a standardised and interpretable measure of deviation that reveals new patterns of neuroanatomical differences across neurological and psychiatric disorders emerging during development and ageing. In sum, brain charts for the human lifespan are an essential first step towards robust, standardised quantification of individual variation and for characterizing deviation from age-related trends. Our global collaborative study
A longitudinal resource for population neuroscience of school-age children and adolescents in China
- Author
- Adamson Chris
- Adler Sophie
- Alexander-Bloch Aaron F.
- Anagnostou Evdokia
- Anderson Kevin M.
- Areces-Gonzalez Ariosky
- Astle Duncan E.
- Auyeung Bonnie
- Ayub Muhammad
- Ball Gareth
- Bao Min
- Baron-Cohen Simon
- Beare Richard
- Bedford Saashi A.
- Benegal Vivek
- Bethlehem Richard A. I.
- Beyer Frauke
- Bin Bae Jong
- Binette Alexa Pichet
- Blangero John
- Boardman James P.
- Borzage Matthew
- Bosch-Bayard Jorge F.
- Bourke Niall
- Bullmore Edward T.
- Cabez Manuel Blesa
- Calhoun Vince D.
- Cao Li-Zhi
- Castellanos F. Xavier
- Chakravarty Mallar M.
- Chang Da
- Chen Antao
- Chen Christina
- Chen Jing
- Chen Li-Zhen
- Chen Xu
- Chertavian Casey
- Chetelat Gael
- Chong Yap S.
- Corvin Aiden
- Costantino Manuela
- Courchesne Eric
- Crivello Fabrice
- Cropley Vanessa L.
- Crosbie Jennifer
- Crossley Nicolas
- Delarue Marion
- Delorme Richard
- Desrivieres Sylvane
- Devenyi Gabriel
- Di Biase Maria A.
- Ding Jinfeng
- Dolan Ray
- Donald Kirsten A.
- Dong Hao-Ming
- Dong Xue
- Donohoe Gary
- Du Yi
- Dunlop Katharine
- Edwards Anthony D.
- Elison Jed T.
- Ellis Cameron T.
- Elman Jeremy A.
- Eyler Lisa
- Fair Damien A.
- Fan Xue-Ru
- Feng Chen
- Feng Tingyong
- Fletcher Paul C.
- Fonagy Peter
- Franz Carol E.
- Fu Xiaolan
- Galan-Garcia Lidice
- Ge Li-Kun
- Gholipour Ali
- Giedd Jay
- Gilmore John H.
- Glahn David C.
- Gong Zhu-Qing
- Goodyer Ian M.
- Grant P. E.
- Groenewold Nynke A.
- Gunning Faith M.
- Gur Raquel E.
- Gur Ruben C.
- Hammill Christopher F.
- Hansson Oskar
- He Ye
- Hedden Trey
- Heinz Andreas
- Henson Richard N.
- Heuer Katja
- Hoare Jacqueline
- Holla Bharath
- Holmes Avram J.
- Hong Bao
- Hou Xiao-Hui
- Hou Xiaohui
- Hu Xiaomeng
- Huang Hao
- Huang Wenjun
- Im Kiho
- Ipser Jonathan
- Jack Clifford R., Jr.
- Jackowski Andrea P.
- Jia Tianye
- Jiang Chao
- Jiang Lili
- Jones David T.
- Jones Peter B.
- Kahn Rene S.
- Karlsson Hasse
- Karlsson Linnea
- Kawashima Ryuta
- Ke Li
- Kelley Elizabeth A.
- Kern Silke
- Kim Ki-Woong
- Kitzbichler Manfred G.
- Kremen William S.
- Lalonde Francois
- Landeau Brigitte
- Lerch Jason
- Lewis John D.
- Li Hui-Jie
- Li Jiao
- Li Li
- Li Qi
- Li Su
- Liao Wei
- Liston Conor
- Liu Xun
- Lombardo Michael V.
- Lv Jinglei
- Mallard Travis T.
- Marcelis Machteld
- Mathias Samuel R.
- Mazoyer Bernard
- McGuire Philip
- Meaney Michael J.
- Mechelli Andrea
- Milham Michael Peter
- Misic Bratislav
- Mo Fan
- Morgan Sarah E.
- Mothersill David
- Nie Jing-Jing
- Ortinau Cynthia
- Ossenkoppele Rik
- Ouyang Minhui
- Palaniyappan Lena
- Paly Leo
- Pan Pedro M.
- Pantelis Christos
- Park Min Tae M.
- Paus Tomas
- Pausova Zdenka
- Paz-Linares Deirel
- Pierce Karen
- Qian Xing
- Qiu Anqi
- Qiu Jiang
- Raznahan Armin
- Rittman Timothy
- Rodrigue Amanda
- Rollins Caitlin K.
- Romero-Garcia Rafael
- Ronan Lisa
- Rong Meng-Jie
- Rosenberg Monica D.
- Rowitch David H.
- Salum Giovanni A.
- Satterthwaite Theodore D.
- Schaare H. Lina
- Schachar Russell J.
- Scholl Michael
- Schultz Aaron P.
- Seidlitz Jakob
- Sharp David
- Shinohara Russell T.
- Skoog Ingmar
- Smyser Christopher D.
- Sperling Reisa A.
- Stein Dan J.
- Stolicyn Aleks
- Su Xue-Quan
- Suckling John
- Sui Dan-Yang
- Sullivan Gemma
- Thyreau Benjamin
- Toro Roberto
- Traut Nicolas
- Tsvetanov Kamen A.
- Turk-Browne Nicholas B.
- Tuulari Jetro J.
- Tzourio Christophe
- Vachon-Presseau Etienne
- Valdes-Sosa Mitchell J.
- Valdes-Sosa Pedro A.
- Valk Sofie L.
- van Amelsvoort Therese
- Vandekar Simon N.
- Vasung Lana
- Vertes Petra E.
- Victoria Lindsay W.
- Villeneuve Sylvia
- Villringer Arno
- Vogel Jacob W.
- Wagstyl Konrad
- Wang Fei
- Wang Ping
- Wang Yin-Shan
- Warfield Simon K.
- Warrier Varun
- Wei Gao-Xia
- Westman Eric
- Westwater Margaret L.
- Whalley Heather C.
- White Simon R.
- Witte A. Veronica
- Wu Yiyang
- Xia Haishuo
- Xu Ting
- Yan Chao-Gan
- Yan Zhi-Xiong
- Yang Ning
- Yang Xiaohong
- Yeo B. T. Thomas
- Yun Hyuk Jin
- Zalesky Andrew
- Zang Yu-Feng
- Zar Heather J.
- Zettergren Anna
- Zhang Jia-Xin
- Zhang Lei
- Zhang Qing
- Zhang Wenfang
- Zhang Yi-Wen
- Zhang Zhe
- Zhao Ke
- Zhou Juan H.
- Zhou Quan
- Zhou Yuan
- Zhu Liqi
- Zhu Xing-Ting
- Zhuo Yan
- Ziauddeen Hisham
- Zugman Andre
- Zuo Xi-Nian
- Zuo Zhentao
- Publication venue
- NATURE PORTFOLIO
- Publication date
- 21/08/2023
- Field of study
During the past decade, cognitive neuroscience has been calling for population diversity to address the challenge of validity and generalizability, ushering in a new era of population neuroscience. The developing Chinese Color Nest Project (devCCNP, 2013-2022), the first ten-year stage of the lifespan CCNP (2013-2032), is a two-stages project focusing on brain-mind development. The project aims to create and share a large-scale, longitudinal and multimodal dataset of typically developing children and adolescents (ages 6.0-17.9 at enrolment) in the Chinese population. The devCCNP houses not only phenotypes measured by demographic, biophysical, psychological and behavioural, cognitive, affective, and ocular-tracking assessments but also neurotypes measured with magnetic resonance imaging (MRI) of brain morphometry, resting-state function, naturalistic viewing function and diffusion structure. This Data Descriptor introduces the first data release of devCCNP including a total of 864 visits from 479 participants. Herein, we provided details of the experimental design, sampling strategies, and technical validation of the devCCNP resource. We demonstrate and discuss the potential of a multicohort longitudinal design to depict normative brain growth curves from the perspective of developmental population neuroscience. The devCCNP resource is shared as part of the "Chinese Data-sharing Warehouse for In-vivo Imaging Brain" in the Chinese Color Nest Project (CCNP) - Lifespan Brain-Mind Development Data Community (https://ccnp.scidb.cn) at the Science Data Bank
Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries
- Author
- A.A. Essam
- A.B. Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman K.Z. Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled Abdrabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B. Hassanein
- Adel Denewar
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adesoji O. Ademuyiwa
- Adewale Adeniyi
- Adewale O. Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Abd Elsameea
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Al-Khatib
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M. Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed mohamed Ibrahim
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Saidbadr
- Ahmed Shahine
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- Wai Him Lam
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- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Weihei Dao
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wiktor Rutkowski
- William Appeadu-Mensah
- William Bonney
- William English
- Willy Alcca Ticona
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yakubu Momohsani Adinoyi
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda
- Ysabel Esthefany Alejos Bermúdez
- Yucel Cengiz
- Yucel Cengiz
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ömer Faruk Toto
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/09/2023
- Field of study
Background: This study assessed the potential cost-effectiveness of high (80–100%) vs low (21–35%) fraction of inspired oxygen (FiO2) at preventing surgical site infections (SSIs) after abdominal surgery in Nigeria, India, and South Africa. Methods: Decision-analytic models were constructed using best available evidence sourced from unbundled data of an ongoing pilot trial assessing the effectiveness of high FiO2, published literature, and a cost survey in Nigeria, India, and South Africa. Effectiveness was measured as percentage of SSIs at 30 days after surgery, a healthcare perspective was adopted, and costs were reported in US dollars ().Results:HighFiO2maybecost−effective(cheaperandeffective).InNigeria,theaveragecostforhighFiO2was216 compared with 222forlowFiO2leadingtoa −6 (95% confidence interval [CI]: −13to −1) difference in costs. In India, the average cost for high FiO2 was 184comparedwith195 for low FiO2 leading to a −11(9515 to −6)differenceincosts.InSouthAfrica,theaveragecostforhighFiO2was1164 compared with 1257forlowFiO2leadingtoa −93 (95% CI: −132to −65) difference in costs. The high FiO2 arm had few SSIs, 7.33% compared with 8.38% for low FiO2, leading to a −1.05 (95% CI: −1.14 to −0.90) percentage point reduction in SSIs. Conclusion: High FiO2 could be cost-effective at preventing SSIs in the three countries but further data from large clinical trials are required to confirm this
Empagliflozin in Patients with Chronic Kidney Disease
- Author
- Aamir Navivala
- Abdulwahab Arbi
- Abegail Hernandez Pena
- Abraham Hanburry
- Adedolapo Adeleke
- Adeera Levin
- Adil Hazara
- Adline Ghazi
- Agnes Masengu
- Ahmad Tuffaha
- Ahmed Awad
- Ahmed Ghanem
- Ai Fukasawa
- Aik Kheng Lee
- Aiko Terakawa
- Aiko Tomita
- Aiko Yamada
- Ailsa Geddes
- Airi Sato
- Akane Katanosaka
- Akane Yamamoto
- Akihiro Fujimoto
- Akihiro Katayama
- Akihito Tanaka
- Akiko Fujita
- Akiko Hashimoto
- Akiko Ishiguro
- Akiko Omata
- Akimasa Asai
- Akinwande Akinfolarin
- Akio Kanazawa
- Akiyo Nishiyama
- Akiyo Tanabe
- Alastair Rankin
- Alastair Woodman
- Albert Hing
- Albert Power
- Alberto Rosati
- Aldo P Maggioni
- Aldo Peixoto
- Aleksandra Murawska
- Alessandro D'Amelio
- Alex Aguilera
- Alex Baxter
- Alex Howson
- Alexa Wonnacott
- Alexander Hadley
- Alexander Hodakowski
- Alexander Paliege
- Alexis Africano
- Alexis Stevenson
- Alfio Giuffrida
- Alfred K Cheung
- Alia Hasan
- Alia Zubaidah Bahtar
- Alice Aitken
- Alice Guerini
- Aliseiya Garza
- Alison Cowley
- Alison Jenkins
- Alison Timadjer
- Allen Young
- Allison Leslie
- Amalia Caamano
- Amanda Aliu
- Amanda Axler
- Amanda Davis
- Amanda Scott
- Amanda Tyler
- Amar Ali
- Amber Avery
- Amber Hurst
- Amelia Te
- Ami Inamori
- Amin Oomatia
- Amir Kazory
- Amret Hawfield
- Amritanshu Pandey
- Amy Hudson
- Amy Hunter
- Amy Mottl
- Ana Moncada
- Anand Srivastava
- Anastassiya Reisler
- Anca Gherman
- Andre Valleteau
- Andrea Lorimer
- Andrea Schwab
- Andrea Webster
- Andrea Wilson
- Andreas Schneider
- Andrew Breach
- Andrew Connor
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- Shunsuke Goto
- Shweta Bansal
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- Sibylle J Hauske
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- Simona Barberi
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- Sina Rolfsmeier
- Sion Roy
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- Siti Nabilah Mohamad Zaini
- Smeeta Sinha
- Smita Gunda
- Sodai Kubota
- Sofia Dayi
- Sonja Grotjahn
- Sonoka Yamamoto
- Soo Kun Lim
- Soon Yi Sor
- Sorcha Mulligan
- Sri Yarlagadda
- Sridhar Ramanaidu
- Srinivasan Beddhu
- Stacey-Ann Villaruel
- Stacie Hitchcock
- Stacy Gillham
- Staplin Natalie
- Stefan Degenhardt
- Stefan Haack
- Stefan Hantel
- Stefanie Jones
- Stefanie Kuhn
- Stephan Matthias
- Stephanie Bolton
- Stephanie Estcourt
- Stephanie Evans
- Stephanie Martinez
- Stephanie Rosenberg
- Stephanie Watson
- Stephanie Whittaker
- Stephany Topping
- Stephen Aronoff
- Steubl Dominik
- Steven Nagelberg
- Stevens Will
- Stewart Moffat
- Subash Somalanka
- Subha Clarke
- Subrata Debnath
- Sucharit Joshi
- Sue Ann Lee
- Sue Hewins
- SueAnn Squyres
- Sui Phin Kon
- Sunil Bhandari
- Sunita Bavanandan
- Suresh Ramadoss
- Suria Junus
- Susan Haskett
- Susan Hurley
- Susan McLaughlin
- Susannah Pajak
- Susanne Bodine
- Susanne Brenner
- Susumu Nakatani
- Suzannah Dorey
- Sybille Merscher
- Tabbatha Duck
- Tabinda Dugal
- Tadahiro Tomita
- Taeko Uchida
- Tai Meng Chen
- Takahiro Ishikawa
- Takahiro Kato
- Takahiro Matsunaga
- Takahiro Yamano
- Takako Kuramae
- Takako Ozawa
- Takanori Hyo
- Takashi Funayama
- Takashi Kadowaki
- Takashi Kobayashi
- Takashi Udagawa
- Takatoshi Otani
- Takayuki Katsuno
- Takehiko Wada
- Takehiro Sugiyama
- Takeshi Kurose
- Takeshi Miyatsuka
- Takeshi Ogihara
- Takuji Ishimoto
- Takuma Kojo
- Takuya Haraguchi
- Takuya Yokoyama
- Tamaki Sasaki
- Tamara Isakova
- Tammi Glider
- Tammy Ross
- Tanaji Dasgupta
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- Tanvi Talsania
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- Tatsuhito Himeno
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- Tejas Patel
- Teresa Kozlowski
- Teresa McKinley
- Terri Chant
- Tetsuya Hosooka
- Tetsuya Shigehara
- Thahir Abdul-Samad
- The EMPA-KIDNEY Collaborative Group: Colin Baigent
- Theresa McCarthy
- Thiemo Pfab
- Thisun Saram
- Thomas Arnold
- Thomas Jones
- Thomas Phillips
- Thomas Pickett
- Thomas Sitter
- Thomas Walters
- Thomas Weinreich
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- Tina Harding
- Tina Ramsey
- Ting Meng
- Tingting Kan
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- Toluleyi Sobande
- Tomoe Sato
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- Tomohito Gohda
- Tomohito Izumi
- Tomoka Nakamura
- Tomoki Kosugi
- Tomoko Hisatake
- Tomoko Morisaki
- Tomoko Takahashi
- Tomoko Takai
- Tomonori Hasegawa
- Tomoya Mita
- Torsten Schramm
- Toru Ikeda
- Toshiki Kano
- Toshimasa Yamauchi
- Toshiya Yamamoto
- Toshiyuki Komiya
- Toyoyoshi Uchida
- Tracey Cummins
- Tracy Fuller
- Tracy Spinola
- Trevor Greene
- Tricia Young
- Tristan Daniels
- Tsukasa Iwakura
- Tuttle Katherine R
- Tze Jian Ng
- Ulla Ludwig
- Ulrike Giebeln-Hudnell
- Ulrike Schmidt
- Urs Benck
- Ursula Hohenstatt
- Usah Lilavivat
- Vahid Mahabadi
- Vanessa Rivers
- Verlaine Stewart-Ray
- Veronica Poma
- Veronica Yousif
- Vesta Lai
- Vicki Adell
- Vicki Brindle
- Vicki Dodds
- Vicki Donley
- Vickie Jones
- Victoria Carnall
- Victoria Gonce
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- Vinay Varad
- Vittorio Ortalda
- Vivian Yiu
- Vladimir Cejka
- Volker Schettler
- Volker Vielhauer
- Wael Eid
- Wagdy Basily
- Wakako Isari
- Wallendszus Karl
- Waltraud Kmietschak
- Wan Ahmad Faizal Alaidin Razali
- Wan Hazlina Wan Mohamad
- Wanner Christoph
- Waqar Ayub
- Waseem Karsan
- Wasim Deeb
- Wasim Hanif
- Wataru Ogawa
- Wei Wang
- Wei Wei
- Weijing Bian
- Weiping Hou
- Weixin Kong
- Wen Jiun Liu
- Wen Liu
- Wendy Arriaga
- Wiebke Kaluza-Schilling
- Will Stevens
- William Durham
- William G Herrington
- William G Herrington
- William Hodge
- William Petchey
- Wolf-Adam Seeger
- Wolfgang Seeger
- Wuhanbilige Hundei
- Xavier Rossello
- Xia Song
- Xiangcheng Xiao
- Xiaojing Jiao
- Xiaojue Li
- Xiaoliang Wang
- Xinzhou Zhang
- Xiumei Hu
- Xuejiao Liu
- Xueying Wang
- Yan Li
- Yanmei Xu
- Yanping Wang
- YanRu Qiao
- Yanwu Yu
- Yanyun Xie
- Yao Weng
- Yao Yao
- Yasemin Kavak
- Yasuhiko Furukawa
- Yasuhiko Ito
- Yasuhiko Kanaguchi
- Yasuhiro Suzuki
- Yasushi Iwaita
- Ye Mun Low
- Yee Yan Lee
- Yew Fong Liew
- Yi Loon Tye
- Yik Hong Wong
- Yik Shen Lim
- Ying Hu
- Ying Jiang
- Ying Kuan
- Ying Lu
- Yinghua Chen
- Yohei Ejima
- Yoko Inukai
- Yolanda Miller
- Yong Chieh Chan
- Yonghong Bu
- Yoshiaki Morishita
- Yoshie Shibata
- Yoshifumi Tamura
- Yoshihiko Yamasaki
- Yoshihisa Wada
- Yoshikazu Tamori
- Yoshiki Suzuki
- Yoshimitsu Yamasaki
- Yoshinari Yasuda
- Yoshinori Osaki
- Yoshiro Kato
- Yoshiyuki Hamamoto
- Yosuke Hirakawa
- Yosuke Nakagawa
- Youcef Mostefai
- Young Lee-Barkey
- Yu An
- Yu Chen
- Yu Chen Ong
- Yu Yamanouchi
- Yuana Mohd Yusoff
- Yuichiro Munakata
- Yuji Oe
- Yuka Sato
- Yuka Ueda
- Yukari Miura
- Yuki Fujita
- Yuki Fukao
- Yuki Omori
- Yukihiro Shimizu
- Yukihiro Yamaji
- Yukiko Nakayama
- Yukiko Toyonaga
- Yukiko Wakita
- Yuko Katsuda
- Yuko Makita
- Yuko Okada
- Yuko Orimo
- Yumi Osawa
- Yushi Hirota
- Yusuke Suzuki
- Yutaka Kamimura
- Yuya Nishida
- Yvette Webley
- Yvonne Ehrl
- Yvonne Jackson
- Zabrina Lozon
- Zaid Azhari
- Zaiha Harun
- Zainab Sheriff
- Zanaida Cooper
- Zay Htet
- Zhang Duan Tham
- Zhi-Hong Liu
- Zhirui Zhao
- Zhu Doreen
- Zhuo Tang
- Zohreh Forghani
- Zuber Patel
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2023
- Field of study
Background The effects of empagliflozin in patients with chronic kidney disease who are at risk for disease progression are not well understood. The EMPA-KIDNEY trial was designed to assess the effects of treatment with empagliflozin in a broad range of such patients. Methods We enrolled patients with chronic kidney disease who had an estimated glomerular filtration rate (eGFR) of at least 20 but less than 45 ml per minute per 1.73 m(2) of body-surface area, or who had an eGFR of at least 45 but less than 90 ml per minute per 1.73 m(2) with a urinary albumin-to-creatinine ratio (with albumin measured in milligrams and creatinine measured in grams) of at least 200. Patients were randomly assigned to receive empagliflozin (10 mg once daily) or matching placebo. The primary outcome was a composite of progression of kidney disease (defined as end-stage kidney disease, a sustained decrease in eGFR to < 10 ml per minute per 1.73 m(2), a sustained decrease in eGFR of & GE;40% from baseline, or death from renal causes) or death from cardiovascular causes. Results A total of 6609 patients underwent randomization. During a median of 2.0 years of follow-up, progression of kidney disease or death from cardiovascular causes occurred in 432 of 3304 patients (13.1%) in the empagliflozin group and in 558 of 3305 patients (16.9%) in the placebo group (hazard ratio, 0.72; 95% confidence interval [CI], 0.64 to 0.82; P < 0.001). Results were consistent among patients with or without diabetes and across subgroups defined according to eGFR ranges. The rate of hospitalization from any cause was lower in the empagliflozin group than in the placebo group (hazard ratio, 0.86; 95% CI, 0.78 to 0.95; P=0.003), but there were no significant between-group differences with respect to the composite outcome of hospitalization for heart failure or death from cardiovascular causes (which occurred in 4.0% in the empagliflozin group and 4.6% in the placebo group) or death from any cause (in 4.5% and 5.1%, respectively). The rates of serious adverse events were similar in the two groups. Conclusions Among a wide range of patients with chronic kidney disease who were at risk for disease progression, empagliflozin therapy led to a lower risk of progression of kidney disease or death from cardiovascular causes than placebo
Use of Telemedicine for Post-discharge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review with Meta-analysis
- Author
- A B Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman Kz Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled Abdrabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B Hassanein
- Adel Denewar
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji Ademuyiwa
- Adesoji Ademuyiwa
- Adesoji O Ademuyiwa
- Adesoji O Ademuyiwa
- Adewale Adeniyi
- Adewale Adisa
- Adewale O Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Abd Elsameea
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Al-Khatib
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Saidbadr
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M Kandil
- Ahmedglal Elnagar
- Ahmet Murat Pektaş
- Aia Mehdi
- Aida Suarez
- Aidan Haslegrave
- Ainhoa Costas-Chavarri
- Aized Raza Shahbaz
- Akin Olaolorun
- Akinlabi Ajao
- Al Faifi Jubran
- Ala Shamasneh
- Alaa Al-Buhaisi
- Alaa Bowabsak
- Alaa El Jamassi
- Alaa Elazab
- Alaa Elhadad
- Alaa Fergany
- Alaa Shaheen
- Alaba Adesina
- Alberto Miyar de León
- Alberto Peón
- Alberto Realis Luc
- Alejandro Matheu
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alex Makupe
- Alex Reece-Smith
- Alexander Canta Calua
- Alexander Smedley
- Alexandra Gerosa
- Alexia Farrugia
- Alexia Farrugia
- Alexis Arnaud
- Alexis Pierre Arnaud
- Alfio Alessandro Russo
- Alfredo Gulielmi
- Ali Ababneh
- Ali Abo El Dahab
- Ali Adam
- Ali Guner
- Ali Khan Niazi
- Ali Mussad
- Aliaksandr Filatau
- Aliang Latif
- Alibeth Andres Baquero Suarez
- Alice Murray
- Alina Robledo-Rabanal
- Aline Broch
- Alisha Bhatt
- Alissa Gübeli
- Alistair Rocke
- Aliyu Ndajiwo
- Aliyu Ndajiwo
- Alphonse Zeta Mutabazi
- Alphonse Zeta Mutabazi
- Alvaro Enrique Mendoza Beleño
- Alvin Ee Zhiun Cheah
- Aly Abd Elrazek
- Aly Sanad
- Alyaa Halim Elgendy
- Amal Ibrahim
- Amany Eldosouky Mohammed
- Amar Kourdouli
- Amar Kourdouli
- Amgad Al Meligy
- Amina Abdelhamid
- Aminah Hanum Haji Abdul Majid
- Aminu Mohammad Samson Olori
- Amir Ait Kaci
- Amira Elsawy
- Amira Hassan Bekhet
- Amira Reda
- Amjad Abu Qumbos
- Amjad Elmashala
- Ammar Gado
- Amna Mamdouh Mohamed
- Amna Mohamed
- Amr Ahmed Saleh
- Amr Hassaan
- Amr Hossameldin
- Amreen Faruq
- Amro Aglan
- Ana Lucia Contreras-Vergara
- Ana Maria Sandoval Barrantes
- Anahita Mansuri
- Anan Rady Abdelazeam
- Anass Majbar
- Anastasios Stefanopoulos
- Anders Thorell
- Andre L Mihaljevic
- Andre Navarro
- Andrea Armellini
- Andrea Belli
- Andrea Bondurri
- Andrea Craus-Miguel
- Andrea Natili
- Andrea Ruzzenente
- Andrea Simioni
- Andreass Haloho
- Andrejus Subocius
- Andrew Kirby
- Andrey Litvin
- Andrius Burmistrovas
- Aneel Bhangu
- Aneel Bhangu
- Aneel Bhangu
- Angel David Pérez Rojas
- Angela Dell
- Angela Mazzella
- Angelica Genoveva Vergara Mejia
- Angeline Charles
- Angelo Antoniozzi
- Angelo Benevento
- Angelos Tselos
- Anil Kaul
- Anil Semiz
- Anita Slade
- Ankur Bhatnagar
- Anmar Homeida
- Anna Jeffery
- Anna Jeffery
- Anna Lasek
- Anna Maffioli
- Anna Rinaldi
- Anna Verbeek
- Annalisa Lo Conte
- Annamaria Bigaran
- Annisa Dewi Fitriana Mukin
- Antanas Gulbinas
- Antanas Zadoroznas
- Anthonius Santoso Rulie
- Anthony Ajiboye
- Anthony Avoka
- Anthony Chuk-Him Lai
- Anthony Davor
- Anthony Sander
- Antoinette Bediako-Bowan
- Antonella La Brocca
- Antonio Nocito
- Antonio Picardo
- Antonio Ramos de la Medina
- Antonio Ramos-De la Medina
- Antonio Ramos-De la Medina
- Antonio Ramos-De la Medina
- Antonio Taddei
- Anwar Atiyeh
- Anyomih Theophilus Teddy Kojo
- Anyomih Theophilus Teddy Kojo
- April Camilla Roslani
- Aram Abdelhaq
- Arazzelly Del Pilar Paucar
- Arcangelo Picciariello
- Arestis Sokratous
- Arezo Kanani
- Ari Leppäniemi
- Ariadne L'Heveder
- Arianna Birindelli
- Arij Ibrahim
- Arjun Paramasivan
- Arlindawati Suyadi
- Armando José Román Velásquez
- Arnav Agarwal
- Arnav Agarwal
- Aroub Alkaaki
- Arturas Vaicius
- Arvin Khamajeet
- Arvo Reinsoo
- Arwa Abouzaid
- Arwa Elfarargy
- Arwa Ibrahim
- Arwa Mohamed
- Asad Choudhry
- Asaf Kedar
- Asdaq Ahmed
- Aseel Alnusairat
- Aseel Hamarshi
- Aseel Musleh
- Ashish Gupta
- Ashish Minocha
- Ashraf Maghrabi
- Ashrafun Nessa
- Ashrarur Rahman Mitul
- Ashwath Bandi
- Asmaa Rezq
- Asmaa Salah
- Asnel Dorismé
- Aspasia Papailia
- Astrid Leusink
- Ataa Ahmed
- Athanasia Bamicha
- Athar Abbas
- Athirah Zulkifli
- Athula Tennakoon
- Attia Attia
- Audrey Clarissa
- Audrius Dulskas
- Audrius Parseliunas
- Augusto Zani
- Augusto Zani
- Aurel Mironescu
- Aurel Mironescu
- Aurel Sandu Mironescu
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- Aya AbdelFatah Ibraheem
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- Aya El-Sawy
- Aya Firwana
- Aya Hammad
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- Aya Yehia Ata
- Ayah Hamdan
- Ayat Hassaan
- Ayman And Taher
- Ayman Salman
- Ayman Shwky
- Azher Herebat
- Azmina Verjee
- Babajide Adenekan
- Babatunde Odeyemi
- Badr Eldin Adel
- Badreldin Adel Tawfik
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- Bahar Busra Ozkan
- Bakeer Mohamed
- Basant Kumar
- Basant Kumar
- Basant Kumar
- Bashir Bello
- Basma Mahmoud
- Basmah Alhassan
- Bassant Mowafy
- Beatrice Brunoni
- Behrad Barmayehvar
- Belen Sanchez
- Benoît Parmentier
- Berk Baris Ozmen
- Berna Buse Kobal
- Bernard Limoges
- Bernhard Wolf
- Bertrand Dousset
- Besmir Grizhja
- Bettina Lieske
- Bettina Lieske
- Betty Maillot
- Bogdan Diaconescu
- Britta Dedekind
- Bruce Biccard
- Bruno Noukpozounkou
- Bryar Kadir
- Busra Murutoglu
- Bárbara Málaga
- Calogero Iacono
- Calvin Eng
- Cameron Fairfield
- Camila Sanchez Samaniego
- Camilla Cona
- Can Adıyaman
- Carla Soldevila-Verdeguer
- Carlo Corbellini
- Carlos Nsengiyumva
- Carlos Paz Galvez
- Carly Bisset
- Carmen Capito
- Carmen Fernández
- Carmen García Bernardo
- Carmina Diaz Zorrilla
- Carolina Guzmán Dueñas
- Caroluce K Musyoka
- Catherine A Shaw
- Catrin Jones
- Catrin Morgan
- Cecile Muller
- Cecilia Costa
- Cedar Andress
- Celeste Caliman
- Celeste Del Basso
- Cesar Miranda
- Cesar Razuri
- Cezar Ciubotaru
- Chali Chibuye
- Challine Alexandre
- Charlene Tan
- Charles Dally
- Chaymae Benyaiche
- Cheewei Gan
- Chelise Currow
- Chelsea Deane
- Chetan Khatri
- Chi Chung Foo
- Chi Ying Jacquelyn Fok
- Chia Kong
- Chimwemwe Kwatiwani
- Chingwan Yip
- Chloe Roy
- Choon Seng Chong
- Chouikh Taieb
- Choy Ling Tan
- Chris Bode
- Christel Leanne Almanon
- Christian Lari Coompson
- Christina Panteli
- Christine Mizzi
- Christoforos Ferousis
- Christopher Owen
- Christopher Smith
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- Christos Anthoulakis
- Christos Barkolias
- Chu-Ann Chai
- Chui Yee Wong
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- Ciskje Zarb
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- Clare Skerritt
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- Colombani Jean-Francois
- Cornelius Mukuzunga
- Corrado Bottini
- Cristina Fernandes
- Cristina Pineño-Flores
- Crystal Yern Nee Chow
- Céline Grosos
- D C Grobler
- Damir Ljuhar
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- Demi Gray
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- Dennis Oswald
- Dharminder Dhillon
- Dhruva Ghosh
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- Rofida Elsemelawy
- Roger Schmid
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- Tubasiime Ronald
- Tunde Sholadoye
- Turgut Bora Cengiz
- Twc Mak
- Tyler Rouse
- Tzu-Ling Chen
- Uday Muddebihal
- Umar Muktar
- Umberto Tedeschi
- Umme Salma
- Usama Hantour
- Uttaran Datta
- Vahit Mutlu
- Valdemaras Jotautas
- Valeria Andriola
- Vanessa Msosa
- Vanessa Msosa
- Vania Guglielmo
- Vania Silvestri
- Vasileios Kalles
- Vasileios Kalles
- Vasiliki Soulou
- Vassilis Kalles
- Vedatcan Işler
- Veeranna Shatkar
- Venerand Barendegere
- Veronica Lazzari
- Vicky Jennings
- Victor Dassah
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- Victor Kong
- Victor Nwinee
- Victoria Adeyeye
- Vijaid Upadhyaya
- Viktorija Nevieraite
- Ville Sallinen
- Vincas Jonas Banaitis
- Virginia Jiménez Carneros
- Virginia Ramos Pérez
- Viviana Sollazzo
- Vladimir Khokha
- Volkan Ozben
- Vu Thanh Hien Le
- Vytautas Gaižauskas
- Vytautas Lipnickas
- Wadah Ali
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
- Waleed Thabet
- Walter Ruiz Panez
- Wan Nurul 'Ain Wan Mohd Nasir
- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Weihei Dao
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wiktor Rutkowski
- William Appeadu-Mensah
- William Bonney
- William English
- Willy Alcca Ticona
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong Kuhaendran Gunaseelan
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda Tasneem Idress
- Ysabel Esthefany Alejos Bermúdez
- Yucel Cengiz
- Yucel Cengiz Dmitri Raptis
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ömer Faruk Toto
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2022
- Field of study
Objective: This study aimed to determine whether remote wound reviews using telemedicine can be safely upscaled, and if standardised assessment tools are needed. Summary background data: Surgical site infection is the most common complication of surgery worldwide, and frequently occurs after hospital discharge. Evidence to support implementation of telemedicine during postoperative recovery will be an essential component of pandemic recovery. Methods: The primary outcome of this study was surgical site infection reported up to 30-days after surgery (SSI), comparing rates reported using telemedicine (telephone and/or video assessment) to those with in-person review. The first part of this study analysed primary data from an international cohort study of adult patients undergoing abdominal surgery who were discharged from hospital before 30-days after surgery. The second part combined this data with the results of a systematic review to perform a meta-analysis of all available data conducted in accordance with PRIMSA guidelines (PROSPERO:192596). Results: The cohort study included 15,358 patients from 66 countries (8069 high, 4448 middle, 1744 low income). Of these, 6907 (45.0%) were followed up using telemedicine. The SSI rate reported using telemedicine was slightly lower than with in-person follow-up (13.4% vs. 11.1%, P<0.001), which persisted after risk adjustment in a mixed-effects model (adjusted odds ratio: 0.73, 95% confidence interval 0.63-0.84, P<0.001). This association was consistent across sensitivity and subgroup analyses, including a propensity-score matched model. In nine eligible non-randomised studies identified, a pooled mean of 64% of patients underwent telemedicine follow-up. Upon meta-analysis, the SSI rate reported was lower with telemedicine (odds ratio: 0.67, 0.47-0.94) than in-person (reference) follow-up (I2=0.45, P=0.12), although there a high risk of bias in included studies. Conclusions: Use of telemedicine to assess the surgical wound post-discharge is feasible, but risks underreporting of SSI. Standardised tools for remote assessment of SSI must be evaluated and adopted as telemedicine is upscaled globally