1,482 research outputs found

    Short high fat diet triggers reversible and region specific effects in DCX+ hippocampal immature neurons of adolescent male mice

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    Adolescence represents a crucial period for maturation of brain structures involved in cognition. Early in life unhealthy dietary patterns are associated with inferior cognitive outcomes at later ages; conversely, healthy diet is associated with better cognitive results. In this study we analyzed the effects of a short period of hypercaloric diet on newborn hippocampal doublecortin+ (DCX) immature neurons in adolescent mice. Male mice received high fat diet (HFD) or control low fat diet (LFD) from the 5th week of age for 1 or 2 weeks, or 1 week HFD followed by 1 week LFD. After diet supply, mice were either perfused for immunohistochemical (IHC) analysis or their hippocampi were dissected for biochemical assays. Detailed morphometric analysis was performed in DCX+ cells that displayed features of immature neurons. We report that 1 week-HFD was sufficient to dramatically reduce dendritic tree complexity of DCX+ cells. This effect occurred specifically in dorsal and not ventral hippocampus and correlated with reduced BDNF expression levels in dorsal hippocampus. Both structural and biochemical changes were reversed by a return to LFD. Altogether these studies increase our current knowledge on potential consequences of hypercaloric diet on brain and in particular on dorsal hippocampal neuroplasticity

    Sistemas de produção identificados na Comunidade Tradicional de Antonio Maria Coelho, Corumbá, MS.

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    A comunidade de Antonio Maria Coelho é um povoado tradicional do município de Corumbá, MS sobre a qual se tem poucas informações sócioeconomicas e sobre o perfil produtivo das famílias. A pesquisa teve como objetivo fazer a caracterização socioeconômica e identificar os sistemas de produção predominantes na localidade, com propósito de levantar demandas para geração, adaptação e apropriação de tecnologias desenvolvidas pela Embrapa Pantanal. Os dados foram coletados no período de março de 2006 a março de 2007 através de entrevistas semi-estruturadas, observações e outras técnicas de Diagnóstico Rápido Participativo. Os resultados indicaram como principal sistema de produção o pomar, seguido pela lavoura, basicamente de subsistência, sendo a mão de obra familiar.bitstream/CPAP-2010/57166/1/BP88.pd

    Sistemas de produção identificados na Comunidade Tradicional de Antonio Maria Coelho, Corumbá, MS.

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    A comunidade de Antonio Maria Coelho é um povoado tradicional do município de Corumbá, MS sobre a qual se tem poucas informações sócioeconomicas e sobre o perfil produtivo das famílias. A pesquisa teve como objetivo fazer a caracterização socioeconômica e identificar os sistemas de produção predominantes na localidade, com propósito de levantar demandas para geração, adaptação e apropriação de tecnologias desenvolvidas pela Embrapa Pantanal. Os dados foram coletados no período de março de 2006 a março de 2007 através de entrevistas semi-estruturadas, observações e outras técnicas de Diagnóstico Rápido Participativo. Os resultados indicaram como principal sistema de produção o pomar, seguido pela lavoura, basicamente de subsistência, sendo a mão de obra familiar.bitstream/CPATC-2010/21113/1/BP88.pd

    Bioma Pantanal: da complexidade do ecossistema à conservação, restauração e bioeconomia.

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    O Pantanal é um bioma amplamente conhecido por ser a maior planície inundável do mundo, mais do que isso é um mosaico contendo áreas inundáveis e não inundáveis, floresta decidual, savana (cerrado), florestas ripárias, pastagens, áreas temporárias, áreas permanentemente aquáticas e com formações monodominantes características. É um reservatório de biodiversidade com organismos adaptados aos ciclos de seca, cheia e fogo, requerendo atenção especial para sua conservação e restauração, ainda mais com os desmatamentos e incêndios catastróficos que recentemente ocorreram. Essa região também possui populações indígenas e tradicionais, que detêm inclusive conhecimentos ancestrais sobre a biodiversidade da região e precisam ser incluídas nos planejamentos para a conservação e restauração desse bioma

    Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC

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    The uncertainty on the calorimeter energy response to jets of particles is derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the calorimeter response to single isolated charged hadrons is measured and compared to the Monte Carlo simulation using proton-proton collisions at centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009 and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter response to specific types of particles (positively and negatively charged pions, protons, and anti-protons) is measured and compared to the Monte Carlo predictions. Finally, the jet energy scale uncertainty is determined by propagating the response uncertainty for single charged and neutral particles to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3% for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table, submitted to European Physical Journal

    Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

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    This paper presents measurements of the W+μ+νW^+ \rightarrow \mu^+\nu and WμνW^- \rightarrow \mu^-\nu cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13

    Measurement of the flavour composition of dijet events in pp collisions at root s=7 TeV with the ATLAS detector

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    This paper describes a measurement of the flavour composition of dijet events produced in pp collisions at √s=7 TeV using the ATLAS detector. The measurement uses the full 2010 data sample, corresponding to an integrated luminosity of 39 pb−1. Six possible combinations of light, charm and bottom jets are identified in the dijet events, where the jet flavour is defined by the presence of bottom, charm or solely light flavour hadrons in the jet. Kinematic variables, based on the properties of displaced decay vertices and optimised for jet flavour identification, are used in a multidimensional template fit to measure the fractions of these dijet flavour states as functions of the leading jet transverse momentum in the range 40 GeV to 500 GeV and jet rapidity |y|<2.1. The fit results agree with the predictions of leading- and next-to-leading-order calculations, with the exception of the dijet fraction composed of bottom and light flavour jets, which is underestimated by all models at large transverse jet momenta. The ability to identify jets containing two b-hadrons, originating from e.g. gluon splitting, is demonstrated. The difference between bottom jet production rates in leading and subleading jets is consistent with the next-to-leading-order predictions

    Measurement of χ c1 and χ c2 production with s√ = 7 TeV pp collisions at ATLAS

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    The prompt and non-prompt production cross-sections for the χ c1 and χ c2 charmonium states are measured in pp collisions at s√ = 7 TeV with the ATLAS detector at the LHC using 4.5 fb−1 of integrated luminosity. The χ c states are reconstructed through the radiative decay χ c → J/ψγ (with J/ψ → μ + μ −) where photons are reconstructed from γ → e + e − conversions. The production rate of the χ c2 state relative to the χ c1 state is measured for prompt and non-prompt χ c as a function of J/ψ transverse momentum. The prompt χ c cross-sections are combined with existing measurements of prompt J/ψ production to derive the fraction of prompt J/ψ produced in feed-down from χ c decays. The fractions of χ c1 and χ c2 produced in b-hadron decays are also measured
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