The measurement of rotary shaft seal film thickness.

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Relativistic theory of tidal Love numbers

In Newtonian gravitational theory, a tidal Love number relates the mass multipole moment created by tidal forces on a spherical body to the applied tidal field. The Love number is dimensionless, and it encodes information about the body's internal structure. We present a relativistic theory of Love numbers, which applies to compact bodies with strong internal gravities; the theory extends and completes a recent work by Flanagan and Hinderer, which revealed that the tidal Love number of a neutron star can be measured by Earth-based gravitational-wave detectors. We consider a spherical body deformed by an external tidal field, and provide precise and meaningful definitions for electric-type and magnetic-type Love numbers; and these are computed for polytropic equations of state. The theory applies to black holes as well, and we find that the relativistic Love numbers of a nonrotating black hole are all zero.Comment: 25 pages, 8 figures, many tables; final version to be published in Physical Review

Defensive landscape architecture in modern public spaces

By 2030, we should have universal access to safe, inclusive, and accessible green and public places, especially for women and children, the elderly, and people with disabilities, according to the Sustainable Development Goals. However, the increasing privatisation of land and gentrification of the urban landscape is putting a limit on the amount of public space available for people to express themselves and use the city as they desire. This paper investigates and reviews the literature on defensive architecture, as well as its historical foundations, definitions, implementation, and reason for existence. The findings provide a clear reflection on the growing awareness of extreme defensive landscape architecture typologies such as spikes and other aggressive measures. Finally, the paper offers worldwide best-practice examples and recommendations for ensuring inclusion and safety in public spaces. We argue that in order to design sustainable public spaces, a holistic approach that considers both intangible values and social inclusion is required

Tidal torque induced by orbital decay in compact object binaries

As we observe in the moon-earth system, tidal interactions in binary systems can lead to angular momentum exchange. The presence of viscosity is generally regarded as the condition for such transfer to happen. In this paper, we show how the orbital evolution can cause a persistent torque between the binary components, even for inviscid bodies. This preferentially occurs at the final stage of coalescence of compact binaries, when the orbit shrinks successively by gravitational waves and plunging on a timescale shorter than the viscous timescale. The total orbital energy transferred to the secondary by this torque is ~0.01 of its binding energy. We further show that this persistent torque induces a differentially rotating quadrupole perturbation. Specializing to the case of a secondary neutron star, we find that this non equilibrium state has an associated free energy of 10^47-10^48 erg, just prior to coalescence. This energy is likely stored in internal fluid motions, with a sizable amount of differential rotation. By tapping this free energy reservoir, a preexisting weak magnetic field could be amplified up to a strength of ~10^15 Gauss. Such a dynamically driven tidal torque can thus recycle an old neutron star into a highly magnetized neutron star, with possible observational consequences at merger.Comment: 14 pages, 8 figures, new sections added, accepted on Sept.19, published on MNRA

Relativistic tidal properties of neutron stars

We study the various linear responses of neutron stars to external relativistic tidal fields. We focus on three different tidal responses, associated to three different tidal coefficients: (i) a gravito-electric-type coefficient G\mu_\ell=[length]^{2\ell+1} measuring the \ell^{th}-order mass multipolar moment GM_{a_1... a_\ell} induced in a star by an external \ell^{th}-order gravito-electric tidal field G_{a_1... a_\ell}; (ii) a gravito-magnetic-type coefficient G\sigma_\ell=[length]^{2\ell+1} measuring the \ell^{th} spin multipole moment G S_{a_1... a_\ell} induced in a star by an external \ell^{th}-order gravito-magnetic tidal field H_{a_1... a_\ell}; and (iii) a dimensionless ``shape'' Love number h_\ell measuring the distortion of the shape of the surface of a star by an external \ell^{th}-order gravito-electric tidal field. All the dimensionless tidal coefficients G\mu_\ell/R^{2\ell+1}, G\sigma_\l/R^{2\ell+1} and h_\ell (where R is the radius of the star) are found to have a strong sensitivity to the value of the star's ``compactness'' c\equiv GM/(c_0^2 R) (where we indicate by c_0 the speed of light). In particular, G\mu_\l/R^{2\l+1}\sim k_\ell is found to strongly decrease, as c increases, down to a zero value as c is formally extended to the ``black-hole (BH) limit'' c^{BH}=1/2. The shape Love number h_\ell is also found to significantly decrease as c increases, though it does not vanish in the formal limit c\to c^{BH}. The formal vanishing of \mu_\ell and \sigma_\ell as c\to c^{BH} is a consequence of the no-hair properties of black holes; this suggests, but in no way proves, that the effective action describing the gravitational interactions of black holes may not need to be augmented by nonminimal worldline couplings.Comment: 21 pages, 10 figures. Matches the published versio

Evidence for D1 Dopamine Receptor Activation by a Paracrine Signal of Dopamine in Tick Salivary Glands

Ticks that feed on vertebrate hosts use their salivary secretion, which contains various bioactive components, to manipulate the host's responses. The mechanisms controlling the tick salivary gland in this dynamic process are not well understood. We identified the tick D1 receptor activated by dopamine, a potent inducer of the salivary secretion of ticks. Temporal and spatial expression patterns examined by immunohistochemistry and reverse transcription polymerase chain reaction suggest that the dopamine produced in the basal cells of salivary gland acini is secreted into the lumen and activates the D1 receptors on the luminal surface of the cells lining the acini. Therefore, we propose a paracrine function of dopamine that is mediated by the D1 receptor in the salivary gland at an early phase of feeding. The molecular and pharmacological characterization of the D1 receptor in this study provides the foundation for understanding the functions of dopamine in the blood-feeding of ticks

Spin and quadrupole contributions to the motion of astrophysical binaries

Compact objects in general relativity approximately move along geodesics of spacetime. It is shown that the corrections to geodesic motion due to spin (dipole), quadrupole, and higher multipoles can be modeled by an extension of the point mass action. The quadrupole contributions are discussed in detail for astrophysical objects like neutron stars or black holes. Implications for binaries are analyzed for a small mass ratio situation. There quadrupole effects can encode information about the internal structure of the compact object, e.g., in principle they allow a distinction between black holes and neutron stars, and also different equations of state for the latter. Furthermore, a connection between the relativistic oscillation modes of the object and a dynamical quadrupole evolution is established.Comment: 43 pages. Proceedings of the 524. WE-Heraeus-Seminar "Equations of Motion in Relativistic Gravity". v2: fixed reference. v3: corrected typos in eqs. (1), (57), (85

Shiga Toxin Binding to Glycolipids and Glycans

Background: Immunologically distinct forms of Shiga toxin (Stx1 and Stx2) display different potencies and disease outcomes, likely due to differences in host cell binding. The glycolipid globotriaosylceramide (Gb3) has been reported to be the receptor for both toxins. While there is considerable data to suggest that Gb3 can bind Stx1, binding of Stx2 to Gb3 is variable. Methodology: We used isothermal titration calorimetry (ITC) and enzyme-linked immunosorbent assay (ELISA) to examine binding of Stx1 and Stx2 to various glycans, glycosphingolipids, and glycosphingolipid mixtures in the presence or absence of membrane components, phosphatidylcholine, and cholesterol. We have also assessed the ability of glycolipids mixtures to neutralize Stx-mediated inhibition of protein synthesis in Vero kidney cells. Results: By ITC, Stx1 bound both Pk (the trisaccharide on Gb3) and P (the tetrasaccharide on globotetraosylceramide, Gb4), while Stx2 did not bind to either glycan. Binding to neutral glycolipids individually and in combination was assessed by ELISA. Stx1 bound to glycolipids Gb3 and Gb4, and Gb3 mixed with other neural glycolipids, while Stx2 only bound to Gb3 mixtures. In the presence of phosphatidylcholine and cholesterol, both Stx1 and Stx2 bound well to Gb3 or Gb4 alone or mixed with other neutral glycolipids. Pre-incubation with Gb3 in the presence of phosphatidylcholine and cholesterol neutralized Stx1, but not Stx2 toxicity to Vero cells

Risk to human health related to the presence of perfluoroalkyl substances in food

Acknowledgements: The Panel wishes to thank the following for their support provided to this scientific output as Hearing experts: Klaus Abraham, Esben Budtz-Jørgensen, Tony Fletcher, Philippe Grandjean, Hans Mielke and Hans Rumke and EFSA staff members: Davide Arcella, Marco Binaglia, Petra Gergelova, Elena Rovesti and Marijke Schutte. The Panel wishes to acknowledge all European competent institutions, Member State bodies and other organisations that provided data for this scientific output. The Panel would also like to thank the following authors and co-authors for providing additional information in relation to their respective studies: Berit Granum, Margie M Peden-Adams, Thomas Webster.Peer reviewedPublisher PD