Die ersten Tage im Studium der Wirtschaftsinformatik

Was erwartet mich an der Hochschule? Werde ich den Anforderungen gerecht werden können? Wie ist das in einer Vorlesung? Wie sind die Professoren? Wer studiert außer mir das Fach? Diese und weitere Fragen beschäftigen jeden Studienanfänger. Der Schritt von der Schule oder aus der beruflichen Tätigkeit hin zum Studium ist sehr groß. Wie können wir unseren neuen Studenten am schnellsten alle notwendigen Informationen zukommen lassen? Wie können wir unseren Studienanfängern vermitteln, dass das Studieren miteinander effektiver und effizienter und damit erfolgreich ist? Wie können wir ihnen das erfolgreiche Studieren gleich von Anfang an "beibringen"? Dies sind Fragen, auf die wir Hochschullehrer in jedem Jahr aufs Neue Antworten suchen. --

Metaphase FISH on a Chip: Miniaturized Microfluidic Device for Fluorescence in situ Hybridization

Fluorescence in situ Hybridization (FISH) is a major cytogenetic technique for clinical genetic diagnosis of both inherited and acquired chromosomal abnormalities. Although FISH techniques have evolved and are often used together with other cytogenetic methods like CGH, PRINS and PNA-FISH, the process continues to be a manual, labour intensive, expensive and time consuming technique, often taking over 3 5 days, even in dedicated labs. We have developed a novel microFISH device to perform metaphase FISH on a chip which overcomes many shortcomings of the current laboratory protocols. This work also introduces a novel splashing device for preparing metaphase spreads on a microscope glass slide, followed by a rapid adhesive tape-based bonding protocol leading to rapid fabrication of the microFISH device. The microFISH device allows for an optimized metaphase FISH protocol on a chip with over a 20-fold reduction in the reagent volume. This is the first demonstration of metaphase FISH on a microfluidic device and offers a possibility of automation and significant cost reduction of many routine diagnostic tests of genetic anomalies

Structural sustainability appraisal in BIM

The provision of Application Programming Interface (API) in BIM-enable tools can contribute to facilitating BIM-related research. APIs are useful links for running plug-ins and external programmes but they are yet to be fully exploited in expanding the BIM scope. The modelling of n-Dimensional (nD) building performance measures can potentially benefit from BIM extension through API implementations. Sustainability is one such measure associated with buildings. For the structural engineer, recent design criteria have put great emphasis on the sustainability credentials as part of the traditional criteria of structural integrity, constructability and cost. This paper examines the utilization of API in BIM extension and presents a demonstration of an API application to embed sustainability issues into the appraisal process of structural conceptual design options in BIM. It concludes that API implementations are useful in expanding the BIM scope. Also, the approach including process modelling, algorithms and object-based instantiations demonstrated in the API implementation can be applicable to other nD building performance measures as may be relevant to the various professional platforms in the construction domain

Porous Bead-Based Diagnostic Platforms: Bridging the Gaps in Healthcare

Advances in lab-on-a-chip systems have strong potential for multiplexed detection of a wide range of analytes with reduced sample and reagent volume; lower costs and shorter analysis times. The completion of high-fidelity multiplexed and multiclass assays remains a challenge for the medical microdevice field; as it struggles to achieve and expand upon at the point-of-care the quality of results that are achieved now routinely in remote laboratory settings. This review article serves to explore for the first time the key intersection of multiplexed bead-based detection systems with integrated microfluidic structures alongside porous capture elements together with biomarker validation studies. These strategically important elements are evaluated here in the context of platform generation as suitable for near-patient testing. Essential issues related to the scalability of these modular sensor ensembles are explored as are attempts to move such multiplexed and multiclass platforms into large-scale clinical trials. Recent efforts in these bead sensors have shown advantages over planar microarrays in terms of their capacity to generate multiplexed test results with shorter analysis times. Through high surface-to-volume ratios and encoding capabilities; porous bead-based ensembles; when combined with microfluidic elements; allow for high-throughput testing for enzymatic assays; general chemistries; protein; antibody and oligonucleotide applications

Microfluidic Systems for Pathogen Sensing: A Review

Rapid pathogen sensing remains a pressing issue today since conventional identification methodsare tedious, cost intensive and time consuming, typically requiring from 48 to 72 h. In turn, chip based technologies, such as microarrays and microfluidic biochips, offer real alternatives capable of filling this technological gap. In particular microfluidic biochips make the development of fast, sensitive and portable diagnostic tools possible, thus promising rapid and accurate detection of a variety of pathogens. This paper will provide a broad overview of the novel achievements in the field of pathogen sensing by focusing on methods and devices that compliment microfluidics

Miniaturised devices for dry powder handling in drug formulation

EThOS - Electronic Theses Online ServiceGBUnited Kingdo