Mejorar la salud, una cuestión ciudadana

This paper deals with the main resources of health improvement in a community from a suburban area in Zaragoza, Spain. The sample is a probabilistic form made in different points: areas, streets and houses. The local hospital wanted to know the real health situation of its population, so it designed some questions in a global health survey. We asked the people how their health could be improved. In order to systematize the answers, it was used a mixture of qualitative and quantitative research strategies. The most frequent answer was related to lifestyle (sport, tobacco, coffee, personal cares). It is presented a discussion on the results and the importance of prevention and community participation on the Primary Attention Health System

Functional alterations involved in increased bleeding in hereditary hemorrhagic telangiectasia mouse models

16p.-7 fig.Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal-dominant genetic disorder involving defects in two predominant genes known as endoglin (ENG; HHT-1) and activin receptor-like kinase 1 (ACVRL1/ALK1; HHT-2). It is characterized by mucocutaneous telangiectases that, due to their fragility, frequently break causing recurrent epistaxis and gastrointestinal bleeding. Because of the severity of hemorrhages, the study of the hemostasis involved in these vascular ruptures is critical to find therapies for this disease. Our results demonstrate that HHT patients with high bleeding, as determined by a high Epistaxis Severity Score (ESS), do not have prolonged clotting times or alterations in clotting factors. Considering that coagulation is only one of the processes involved in hemostasis, the main objective of this study was to investigate the overall mechanisms of hemostasis in HHT-1 (Eng+/−) and HHT-2 (Alk1+/−) mouse models, which do not show HHT vascular phenotypes in the meaning of spontaneous bleeding. In Eng+/− mice, the results of in vivo and in vitro assays suggest deficient platelet-endothelium interactions that impair a robust and stable thrombus formation. Consequently, the thrombus could be torn off and dragged by the mechanical force exerted by the bloodstream, leading to the reappearance of hemorrhages. In Alk1+/− mice, an overactivation of the fibrinolysis system was observed. These results support the idea that endoglin and Alk1 haploinsufficiency leads to a common phenotype of impaired hemostasis, but through different mechanisms. This contribution opens new therapeutic approaches to HHT patients' epistaxis.This work was supported by the Junta de Castilla y León (BIO/SA70/14, GRS2135/A/2020, and GRS2314/A/2021), Fundación Mutua Madrileña (FMM AP172142019), the Instituto de Salud Carlos III (PI16/00460 and PI19/01630, co-funded by FEDER), and Consejo Superior de Investigaciones Científicas (CSIC; 201920E022 to CB). CO-I was supported by a contract from the Ministerio de Economía y Competitividad of Spain. CE-T was a fellow from the Fundación Miguel Casado San José.Peer reviewe

Evaluating the Impact of Nature-Based Solutions: A Handbook for Practitioners

The Handbook aims to provide decision-makers with a comprehensive NBS impact assessment framework, and a robust set of indicators and methodologies to assess impacts of nature-based solutions across 12 societal challenge areas: Climate Resilience; Water Management; Natural and Climate Hazards; Green Space Management; Biodiversity; Air Quality; Place Regeneration; Knowledge and Social Capacity Building for Sustainable Urban Transformation; Participatory Planning and Governance; Social Justice and Social Cohesion; Health and Well-being; New Economic Opportunities and Green Jobs. Indicators have been developed collaboratively by representatives of 17 individual EU-funded NBS projects and collaborating institutions such as the EEA and JRC, as part of the European Taskforce for NBS Impact Assessment, with the four-fold objective of: serving as a reference for relevant EU policies and activities; orient urban practitioners in developing robust impact evaluation frameworks for nature-based solutions at different scales; expand upon the pioneering work of the EKLIPSE framework by providing a comprehensive set of indicators and methodologies; and build the European evidence base regarding NBS impacts. They reflect the state of the art in current scientific research on impacts of nature-based solutions and valid and standardized methods of assessment, as well as the state of play in urban implementation of evaluation frameworks

Mejorar la salud, una cuestión ciudadana

Se profundiza en las principales fuentes de mejora de la salud percibida por una zona básica de salud, del barrio de Casablanca, Zaragoza, España. La muestra se obtuvo mediante un muestreo probabilístico polietápico dentro de las actuaciones propias de una encuesta de salud. La pregunta que se realizó de manera abierta fue: ¿cómo puede mejorar su salud?, para su interpretación se utilizaron técnicas cualitativas y cuantitativas. Destacaron aquellas intervenciones que hacían referencia a los estilos de vida y cierta externalidad en cuanto a la responsabilidad de estas mejoras

Mejorar la salud, una cuestión ciudadana

This paper deals with the main resources of health improvement in a community from a suburban area in Zaragoza, Spain. The sample is a probabilistic form made in different points: areas, streets and houses. The local hospital wanted to know the real health situation of its population, so it designed some questions in a global health survey. We asked the people how their health could be improved. In order to systematize the answers, it was used a mixture of qualitative and quantitative research strategies. The most frequent answer was related to lifestyle (sport, tobacco, coffee, personal cares). It is presented a discussion on the results and the importance of prevention and community participation on the Primary Attention Health System

Mejorar la salud, una cuestión ciudadana

This paper deals with the main resources of health improvement in a community from a suburban area in Zaragoza, Spain. The sample is a probabilistic from made in different points: areas, streets and houses. The local hospital wanted to know the real health situation of its population, so it designed some questions in a global health survey. We asked the people how their health could be improved.   In other to systematize the answers, it was used a mixture of qualitative and quantitative research strategies.  The most frequent answers was related to lifestyle (sport, tobacco, coffee, personal cares), it is presented a discussion on the results and the importance of prevention and community participation on the Primary Attention Health System.