43 research outputs found
Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction
- Author
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Background: Current clinical therapy of non-small cell lung cancer depends on histo-pathological classification. This approach poorly predicts clinical outcome for individual patients. Gene expression profiling holds promise to improve clinical stratification, thus paving the way for individualized therapy. Methodology and Principal Findings: A genome-wide gene expression analysis was performed on a cohort of 91 patients. We used 91 tumor- and 65 adjacent normal lung tissue samples. We defined sets of predictor genes (probe sets) with the expression profiles. The power of predictor genes was evaluated using an independent cohort of 96 non-small cell lung cancer- and 6 normal lung samples. We identified a tumor signature of 5 genes that aggregates the 156 tumor and normal samples into the expected groups. We also identified a histology signature of 75 genes, which classifies the samples in the major histological subtypes of non-small cell lung cancer. Correlation analysis identified 17 genes which showed the best association with post-surgery survival time. This signature was used for stratification of all patients in two risk groups. Kaplan-Meier survival curves show that the two groups display a significant difference in post-surgery survival time (p = 5.6E-6). The performance of the signatures was validated using a patient cohort of similar size (Duke University, n = 96). Compared to previously published prognostic signatures for NSCLC, the 17 gene signature performed well on these two cohorts
Highly contractile 3D tissue engineered skeletal muscles from human iPSCs reveal similarities with primary myoblast-derived tissues
- Author
- Publication venue
- Publication date
- 10/10/2023
- Field of study
Skeletal muscle research is transitioning toward 3D tissue engineered in vitro models reproducing muscle's native architecture and supporting measurement of functionality. Human induced pluripotent stem cells (hiPSCs) offer high yields of cells for differentiation. It has been difficult to differentiate high-quality, pure 3D muscle tissues from hiPSCs that show contractile properties comparable to primary myoblast-derived tissues. Here, we present a transgene-free method for the generation of purified, expandable myogenic progenitors (MPs) from hiPSCs grown under feeder-free conditions. We defined a protocol with optimal hydrogel and medium conditions that allowed production of highly contractile 3D tissue engineered skeletal muscles with forces similar to primary myoblast-derived tissues. Gene expression and proteomic analysis between hiPSC-derived and primary myoblast-derived 3D tissues revealed a similar expression profile of proteins involved in myogenic differentiation and sarcomere function. The protocol should be generally applicable for the study of personalized human skeletal muscle tissue in health and disease.</p
Gene expression-based classification of non-small cell lung carcinomas and survival prediction
- Author
- Publication venue
- Publication date
- 14/09/2010
- Field of study
Background: Current clinical therapy of non-small cell lung cancer depends on histo-pathological classification. This approach poorly predicts clinical outcome for individual patients. Gene expression profiling holds promise to improve clinical stratification, thus paving the way for individualized therapy. Methodology and Principal Findings:A genome-wide gene expression analysis was performed on a cohort of 91 patients. We used 91 tumor- and 65 adjacent normal lung tissue samples. We defined sets of predictor genes (probe sets) with the expression profiles. The power of predictor genes was evaluated using an independent cohort of 96 non-small cell lung cancer- and 6 normal lung samples. We identified a tumor signature of 5 genes that aggregates the 156 tumor and normal samples into the expected groups. We also identified a histology signature of 75 genes, which classifies the samples in the major histological subtypes of non-small cell lung cancer. Correlation analysis identified 17 genes which showed the best association with post-surgery survival time. This signature was used for stratification of all patients in two risk groups. Kaplan-Meier survival curves show that the two groups display a significant difference in post-surgery survival time (p = 5.6E-6). The performance of the signatures was validated using a patient cohort of similar size (Duke University, n = 96). Compared to previously published prognostic signatures for NSCLC, the 17 gene signature performed well on these two cohorts. Conclusions:The gene signatures identified are promising tools for histo-pathological classification of non-small cell lung cancer, and may improve the prediction of clinical outcome
Human and animal fertility studies in cystinosis reveal signs of obstructive azoospermia, an altered blood-testis barrier and a subtherapeutic effect of cysteamine in testis
- Author
- Publication venue
- 'Wiley'
- Publication date
- 01/11/2021
- Field of study
Cystinosis is an inherited metabolic disorder caused by autosomal recessive mutations in the CTNS gene leading to lysosomal cystine accumulation. The disease primarily affects the kidneys followed by extra-renal organ involvement later in life. Azoospermia is one of the unclarified complications which are not improved by cysteamine, which is the only available disease-modifying treatment. We aimed at unraveling the origin of azoospermia in cysteamine-treated cystinosis by confirming or excluding an obstructive factor, and investigating the effect of cysteamine on fertility in the Ctnsâ/â mouse model compared with wild type. Azoospermia was present in the vast majority of infantile type cystinosis patients. While spermatogenesis was intact, an enlarged caput epididymis and reduced levels of seminal markers for obstruction neutral α-glucosidase (NAG) and extracellular matrix protein 1 (ECM1) pointed towards an epididymal obstruction. Histopathological examination in human and mouse testis revealed a disturbed blood-testis barrier characterized by an altered zonula occludens-1 (ZO-1) protein expression. Animal studies ruled out a negative effect of cysteamine on fertility, but showed that cystine accumulation in the testis is irresponsive to regular cysteamine treatment. We conclude that the azoospermia in infantile cystinosis is due to an obstruction related to epididymal dysfunction, irrespective of the severity of an evolving primary hypogonadism. Regular cysteamine treatment does not affect fertility but has subtherapeutic effects on cystine accumulation in testis
Generation of genetically matched hiPSC lines from two mosaic facioscapulohumeral dystrophy type 1 patients
- Author
- Brands T. (Tom)
- Buijsen R.A.M. (Ronald)
- Den Hamer B. (Bianca)
- Eussen H.J.F.M.M. (Bert)
- Freund C. (Christian)
- Greef J.C. (Jessica) de
- Klein A. (Annelies) de
- Lemmers R.J.L.F. (Richard)
- Maarel S.M. (Silvre) van der
- Roon-Mom W.M.C. (Willeke) van
- Tawil R. (Rabi)
- Tok M. (Merve)
- Vliet P.J. (Patrick) van der
- Wal E. (Erik) van der
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Facioscapulohumeral dystrophy type 1 (FSHD1) is caused by contraction of the D4Z4 repeat array on chromosome 4q resulting in sporadic misexpression of the transcription factor DUX4 in skeletal muscle tissue. In ~4% of families, de novo D4Z4 contractions occur after fertilization resulting in somatic mosaicism with control and FSHD1 cell populations present within the same patient. Reprogramming of mosaic fibroblasts from two FSHD1 patients into human induced pluripotent stem cells (hiPSCs) generated genetically matched control and FSHD1 hiPSC lines. All hiPSC lines contained a normal karyotype, expressed pluripotency genes and differentiated into cells from the three germ layers
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
- Author
- Abdukahil Sheryl Ann
- Abdukahil Sheryl,
- Abe Ryuzo
- Abel Laurent
- Abreu Julia Rodriguez
- Abreu Julia,
- Absil Lara
- Acker Andrew
- Adachi Shingo
- Adam Elisabeth
- AdriĂŁo Diana
- Ainscough Kate
- Akimoto Takako
- Al Qasim Eman
- Al-Dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alex Beatrice
- Alexandre KĂ©vin
- Alfoudri Huda
- Alidjnou Kazali Enagnon
- Alidjnou Kazali,
- Aliudin Jeffrey
- Allavena Clotilde
- Allou Nathalie
- Alves JoĂŁo
- Alves Rita
- Amaral Maria
- Ammerlaan Heidi
- Ampaw Phoebe
- Andini Roberto
- Andrejak Claire
- Angheben Andrea
- ANGOULVANT François
- Ansart SĂ©verine
- Antonelli Massimo
- Arabi Yaseen
- Aragao Irene
- Arcadipane Antonio
- Arenz Lukas
- Arlet Jean-BenoĂźt
- Arnold-Day Christel
- Arora Lovkesh
- Artaud-Macari Elise
- Asensio Angel
- Assie Jean Baptiste
- Assie Jean,
- Atique Anika
- Auchabie Johann
- Aumaitre Hugues
- Azemar LaurĂšne
- Azoulay CĂ©cile
- Bach Benjamin
- Bachelet Delphine
- Baillie J. Kenneth,
- Bak Erica
- Bakakos Agamemnon
- Banisadr Firouzé
- Barbalho Renata
- Barclay Wendy,
- Barnikel Michaela
- Barrelet Audrey
- Barrigoto Cleide
- Basmaci Romain
- Bassi Gianluigi Li
- Bassi Gianluigi,
- Bedossa Alexandra
- Behilill Sylvie
- Bekken Gry Kloumann
- Bekken Gry,
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beluze Marine
- Benech Nicolas
- Benkerrou Dehbia
- Bennett Suzanne
- Bento LuĂs
- Berdal Jan-Erik
- Bergeaud Delphine
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bhavsar Krishna
- Bissuel François
- Biston Patrick
- Bitker Laurent
- Blanco-Schweizer Pablo
- Blot Mathieu
- Boccia Filomena
- Bogaert Debby
- Bompart François
- Booth Gareth
- Borges Diogo
- Borie Raphaël
- Bos Jeannet
- Bosse Hans Martin
- Bosse Hans,
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller KĂ©vin
- Bouillet Laurence
- Bouisse Camille
- Boureau Anne-Sophie
- Bouscambert Maude
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brickell Kathy
- Brozzi Nicolas
- Buchtele Nina
- Buesaquillo Christian
- Bugaeva Polina
- Buisson Marielle
- Burhan Erlina
- Bustos Ingrid,
- Butnaru Denis
- Cabie André
- Cabral Susana
- Caceres Eder
- Callahan Mia
- Calligy Kate
- Calvache Jose Andres
- Calvache Jose,
- Campana Valentine
- Campbell Paul
- CamÔes João
- Canepa Cecilia
- Cantero Mireia
- Caraux-Paz Pauline
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carney Gayle
- Carpenter Chloe
- Carret Marie-Christine
- Carrier François Martin
- Carrier François,
- Carson Gail
- Casanova Maire-Laure
- CascĂŁo Mariana
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- CastrillĂłn Henry
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cavalin Roberta
- Cavalli Giulio Giovanni
- Cavalli Giulio,
- Cavayas Alexandros
- Ceccato Adrian
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chas Julie
- Chassin Camille
- Chen Anjellica
- Chen Yih-Sharng
- Cheng Matthew Pellan
- Cheng Matthew,
- Cheret Antoine
- Chiarabini Thibault
- Chica Julian
- Chirouze Catherine
- Chiumello Davide
- Cho Hwa Jin
- Cho Hwa,
- Cho Sung Min
- Cho Sung,
- Choez Xavier SĂĄnchez
- Choez Xavier,
- Choileain Orna Ni
- Choileain Orna,
- Cholley Bernard
- Cidade Jose Pedro
- Cidade Jose,
- Citarella Barbara Wanjiru
- Citarella Barbara,
- Ciullo Anna
- Clarke Jennifer
- Clohisey Sara
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Colombo Sebastiano,
- Combs Pamela
- Connelly J.,
- Connor Marie
- Conrad Anne
- Contreras SofĂa
- Cooke Graham,
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cormican Sarah
- Cornelis Sabine
- Corpuz Arianne Joy
- Corpuz Arianne,
- Corvaisier Grégory
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Claudina
- Csete Marc
- Cucino Alberto
- Cullen Caroline
- Cummings Matthew
- Curley Gerard
- Curlier Elodie
- Curto Elena Gallego
- Curto Elena,
- Custodio Paula
- CĂĄrcel Sheila
- Da Silva Filipe Ana
- Da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew,
- Dalton Heidi
- Dalton Jo
- Daneman Nick
- Dankwa Emmanuelle,
- Dantas Jorge
- De AraĂșjo Mariz Carolline
- De Brito Carlos Alexandre Antunes
- De Brito Carlos,
- De Castro Nathalie
- De Mendoza Diego
- De Oliveira França Rafael Freitas
- De Oliveira França Rafael,
- De Rosa Rosanna
- De Silva Thushan
- De Vries Peter
- Dean David
- Debray Marie-Pierre
- Dechert William
- Deconninck Lauren
- Decours Romain
- Delacroix Isabelle
- Delavigne Karen
- Deligiannis Ionna
- Dellâamore Andrea
- Delobel Pierre
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Desai Mehul
- Descamps Diane
- Desvallée Mathilde
- Devouge Eglantine Ferrand
- Devouge Eglantine,
- Dewayanti Santi Rahayu
- Dewayanti Santi,
- Diallo Alpha
- Diamantis Sylvain
- Dias André
- Diaz Juan Jose Diaz
- Diaz Juan,
- DIAZ Rodrigo
- Didier KĂ©vin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet JĂ©rĂŽme
- Dinot Vincent
- Diouf Alphonsine
- Dishon Yael
- Djossou FĂ©lix
- Docherty Annemarie,
- Dominguez Carmen Infante
- Dominguez Carmen,
- Dong Andy
- Donnelly Christl,
- Donnelly Maria
- Donohue Chloe
- Dorival CĂ©line
- Douglas James Joshua
- Douglas James,
- Douma Renee
- Dournon Nathalie
- Downer Triona
- Downing Mark
- Drake Tom
- Dubee Vincent
- DUBOS François
- Ducancelle Alexandra
- Dudman Susanne
- Dunning Jake
- Duranti Silvia
- Durham Lucian
- Dussol Bertrand
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Dyrhol-Riise Anne,
- Dâaragon FrĂ©dĂ©rick
- DâOrleans Charles Crepy
- Dâorleans Charles,
- DâOrtenzio Eric
- Eid Charbel Maroun
- Eid Charbel,
- Eira Carla
- Elapavaluru Subbarao
- Elharrar Brigitte
- Elkheir Natalie
- Ellerbroek Jacobien
- Ellis Rachael
- Eloy Philippine
- Elshazly Tarek
- Enderle Isabelle
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Esperatti Mariano
- Esperou HĂ©lĂšne
- Esposito-Farese Marina
- EstevĂŁo JoĂŁo
- Etienne Manuel
- Ettalhaoui Nadia
- Everding Anna Greti
- Everding Anna,
- Evers Mirjam
- Fabre Isabelle
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron,
- Faria Pedro
- Farshait Nataly
- Fatoni Arie Zainul
- Fatoni Arie,
- Faure Karine
- Fayed Mohamed
- Feely Niamh
- Fernandes Jorge
- Fernandes MarĂlia
- Fernandes Susana
- Ferraz MĂĄrio
- Ferreira Benigno
- Ferrer-Roca Ricard
- FerrĂŁo Joana
- Figueiredo-Mello Claudia
- Flateau Clara
- Fletcher Tom
- Florio Letizia Lucia
- Florio Letizia,
- Foley Claire
- Fomin Victor
- Fonseca Claudio Duarte
- Fonseca Claudio,
- Fonseca Tatiana
- Fontela Patricia
- Forsyth Simon
- Foti Giuseppe
- Fourn Erwan
- Fowler Rob
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John
- Freire Marcela Vieira
- Freire Marcela,
- Friedrich Caren
- Fry Stéphane
- Fuentes Nora
- Fukuda Masahiro
- Gaborieau Valérie
- Gachet BenoĂźt
- Gaci Rostane
- Gagliardi Massimo
- Gagnard Jean-Charles
- Gagneux-Brunon Amandine
- GaiĂŁo SĂ©rgio
- Gallagher Phil
- Gamble Carrol
- Garan Arthur
- Garcia Rebekha
- Garcia-Gallo Esteban
- GarcĂa Ruth NoemĂ Jorge
- GarcĂa Ruth,
- Garot Denis
- Garrait Valérie
- Gault Nathalie
- Gavin Aisling
- Gaymard Alexandre
- Gebauer Johannes
- Germano Nuno
- Ghosn Jade
- Giani Marco
- Giaquinto Carlo
- Gibson Jess
- Gigante Tristan
- Gilg Morgane
- Giordano Guillermo
- Girvan Michelle
- Gissot Valérie
- Giwangkancana Gezy
- Glikman Daniel
- Glybochko Petr
- Gnall Eric
- Goco Geraldine
- Goehringer François
- Goepel Siri
- Goffard Jean-Christophe
- Golob Jonathan
- Gorenne Isabelle
- Goujard CĂ©cile
- Goulenok Tiphaine
- Grable Margarite
- Grandin Edward Wilson
- Grandin Edward,
- Granier Pascal
- Grasselli Giacomo
- Green Christopher,
- Greenhalf William
- Greffe SegolĂšne
- Grieco Domenico Luca
- Grieco Domenico,
- Griffee Matthew
- Griffiths Fiona
- Grigoras Ioana
- Groenendijk Albert
- Gruner Heidi
- Gu Yusing
- Guedj Jérémie
- Guellec Dewi
- Guerguerian Anne-Marie
- Guerreiro Daniela
- Guery Romain
- Guillaumot Anne
- Guilleminault Laurent
- Guimard Thomas
- GĂłmez-Junyent Joan
- Haber Daniel
- Hakak Sheeba
- Hall Matthew
- Halpin Sophie
- Hamer Ansley
- Hamidfar Rebecca
- Hammond Terese
- Hardwick Hayley
- Harley Kristen
- Harrison Ewen,
- Harrison Janet
- Hays Leanne
- Heerman Jan
- Heggelund Lars
- Hendry Ross
- Hennessy Martina
- Henriquez-Trujillo Aquiles
- Hentzien Maxime
- Hernandez-Montfort Jaime
- Herreros Jose Miguel Cisneros
- Herreros Jose,
- Hidayah Astarini
- Higgins Dawn
- Higgins Eibhilin
- Hinton Samuel
- HipĂłlito-Reis Ana
- Hiraiwa Hiroaki
- Hiscox Julian,
- Ho Antonia Ying Wai
- Ho Antonia,
- Hoctin Alexandre
- Hoffmann Isabelle
- Hoiting Oscar
- Holt Rebecca
- Holten Aleksander Rygh
- Holten Aleksander,
- Holter Jan Cato
- Holter Jan,
- Horby Peter
- Horcajada Juan Pablo
- Horcajada Juan,
- Hoshino Koji
- Hoshino Kota
- Hough Catherine,
- Hssain Ali Ait
- Hssain Ali,
- Hsu Jimmy Ming-Yang
- Hulot Jean-SĂ©bastien
- Humaid Felwa Bin
- Humaid Felwa,
- Ijaz Samreen
- Illes Hajnal-Gabriela
- InĂĄcio Hugo
- Iosifidis Elias
- Irvine Lacey
- Isgett Sarah
- Isidoro Tiago
- Isnard Margaux
- Itai Junji
- Ivulich Daniel
- Jaafoura Salma
- Jabot Julien
- Jackson Clare
- Jamieson Nina
- Jaureguiberry Stéphane
- Javidfar Jeffrey
- Jean-BenoĂźt Zabbe
- Jego Florence
- Jenum Synne
- Jimenez Juan Fernado Masa
- Jimenez Juan,
- Johal Simreen Kaur
- Johal Simreen,
- Joseph CĂ©dric
- Joseph Mark
- Jouvet Philippe
- Jung Hanna
- Kafif Ouifiya
- Kaguelidou Florentia
- Kali Sabina
- Kalomoiri Smaragdi
- Kandamby Darshana Hewa
- Kandamby Darshana,
- Kandel Chris
- Kant Ravi
- Kartsonaki Christiana
- Kasugai Daisuke
- Katz Kevin
- Keating Sean
- Kelly Andrea
- Kelly Sadie
- Kennedy Lisa
- Kennon Kalynn
- Kerroumi Younes
- Kestelyn Evelyne
- Khalid Imrana
- Khalil Antoine
- Khan Coralie
- Khan Irfan
- Kho Michelle,
- Khoo Saye
- Kida Yuri
- Kiiza Peter
- Kildal Anders Benjamin
- Kildal Anders,
- Kimmoun Antoine
- Kindgen-Milles Detlef
- Kitamura Nobuya
- Klenerman Paul
- Knight Stephen
- Kobbe Robin
- Korten Volkan
- Kosgei Caroline
- Krawczyk Karolina
- KUMAR Deepali
- Kurtzman Ethan
- Kutsogiannis Demetrios
- Kyriakoulis Konstantinos
- LACHATRE Marie
- Lacoste Marie
- Laffey John,
- Lagrange Marie
- Laine Fabrice
- Lambert Marc
- Lamontagne François
- Langelot-Richard Marie
- Lantang Eka Yudha
- Lantang Eka,
- Lanza Marina
- Laouénan Cédric
- Laribi Samira
- Lariviere Delphine
- Launay Odile
- Lavie-Badie Yoan
- Law Andrew
- Le Bihan Clément
- Le Bris Cyril
- Le Coustumier Eve
- Le Falher Georges
- Le Gac Sylvie
- Le Hingrat Quentin
- Le Maréchal Marion
- Le Mestre Soizic
- Le Moing Vincent
- Le Nagard Hervé
- Le Turnier Paul
- Le Van Tan
- Le Minh
- Leal Ema
- Lee James
- Lee Su Hwan
- Lee Su,
- Lee Todd
- Leeming Gary
- Lefebvre Bénédicte
- Lefebvre Laurent
- Lefevre Benjamin
- Lellouche François
- Lemaignen Adrien
- Lemee VĂ©ronique
- Lemmink Gretchen
- Leone Michela
- Lepiller Quentin
- Lescure François-Xavier
- Lesens Olivier
- Lesouhaitier Mathieu
- Levy Bruno
- Levy Yves
- Levy-Marchal Claire
- LeĂłn Rafael
- Liang Janet
- Lim Wei Shen
- Lim Wei,
- Lina Bruno
- Lind Andreas
- Lingas Guillaume
- Lion-Daolio Sylvie
- Liu Keibun
- Loforte Antonio
- Lolong Navy
- Lopes Diogo
- Lopez-Colon Dalia
- Lordemann Anja Grosse
- Lordemann Anja,
- Loubet Paul
- Lucet Jean Christophe
- Lucet Jean,
- Luna Carlos,
- Lungu Olguta
- Luong Liem
- Luton Dominique
- Lyons Ruth
- LâHer Erwan
- Maasikas Olavi
- Macdonald Sarah
- Machado MoĂŻse
- Macheda Gabrielle
- Madhok Jai
- Mahieu Rafael
- Mahy Sophie
- Maier Lars Siegfrid
- Maier Lars,
- Maillet MylĂšne
- Maitre Thomas
- Malaque Ana
- Maldonado Hugo Miranda
- Maldonado Hugo,
- Malfertheiner Maximilian
- Malik Nadia
- Maltez Fernando
- Malvy Denis
- MAMBERT Marina
- Manda Victoria
- Mandei Jose,
- Mangoni Emanuele Durante
- Mangoni Emanuele,
- Manning Edmund
- Manuel Aldric
- Marino FlĂĄvio
- Marques Ana
- Marquis Catherine
- Marsh Brian
- Marsh Laura
- Marshall John
- Martelli Celina Turchi
- Martelli Celina,
- Martin Dori-Ann
- Martin Emily
- Martin-Blondel Guillaume
- Martin-Loeches Ignacio
- Martin-Quiros Alejandro
- Martinot Martin
- Martins Ana
- Martins JoĂŁo
- Martucci Gennaro
- Marwali Eva Miranda
- Marwali Eva,
- Maslove David
- Mason Sabina
- Matan Moshe
- Mathieu Daniel
- Mattei Mathieu
- Matulevics Romans
- Maulin Laurence
- Mc Evoy Natalie
- Mccarthy Aine
- Mccloskey Colin
- Mcconnochie Rachael
- Mcdermott Sherry
- McDonald Sarah
- Mcelwee Samuel
- Mcevoy Natalie
- McGeer Allison
- Mcguinness Niki
- Mclean Kenneth,
- Mcnicholas Bairbre
- Meaney Edel
- Mear-Passard CĂ©cile
- Mechlin Maggie
- Mele Ferruccio
- Menon Kusum
- Mentré France
- Mentzer Alexander,
- Mercier Noémie
- Merckx Antoine
- Mergler Blake
- Merson Laura
- Mesquita AntĂłnio
- Meybeck AgnĂšs
- Meynert Alison,
- Meyssonnier Vanina
- Meziane Amina
- Mezidi Medhi
- Michelanglei CĂ©line
- MihnovitĆĄ Vladislav
- Mohammed Nassima Si
- Mohammed Nassima,
- Moin Asma
- Molina David
- Molinos Elena
- Mone Mary
- Monteiro Agostinho
- Montes Claudia
- Montrucchio Giorgia
- Moore Sarah
- Moore Shona,
- Morales-Cely Lina
- Morlaes Louis Gerbaud
- Morlaes Louis,
- Moro Lucia
- Motos Ana
- Mouquet Hugo
- Moyet Julien
- Mullaert Jimmy
- Munblit Daniel
- Murphy Derek
- Murris MarlĂšne
- Myrodia Dimitra Melia
- Myrodia Dimitra,
- MĂŒller Fredrik
- MĂŒller Karl Erik
- MĂŒller Karl,
- Neant NadĂšge
- Neb Holger
- Nekliudov Nikita,
- Neto Raul
- Neumann Emily
- Neves Bernardo
- Ng Pauline Yeung
- Ng Pauline,
- Ng Wing Yiu
- Ng Wing,
- Nichol Alistair
- Nonas Stephanie
- Noret Marion
- Norman Lisa
- Notari Alessandra
- Noursadeghi Mahdad
- Nowicka Karolina
- Nseir Saad
- Nunez Jose,
- Nuñez Maria Angelica Rivera
- Nuñez Maria,
- Nyamankolly Elsa
- NâGuyen Yohan
- Occhipinti Giovanna
- Ogston Tawnya
- Ogura Takayuki
- Oh Tak-Hyuk
- Ohshimo Shinichiro
- Oinam Budha Charan Singh
- Oinam Budha,
- Oliveira Ana Pinho
- Oliveira Ana,
- Oliveira JoĂŁo
- Olliaro Piero
- Ong David,
- Oosthuyzen Wilna
- Openshaw Peter,
- Orozco-Chamorro Claudia Milena
- Orozco-Chamorro Claudia,
- Orquera Andrés
- Osatnik Javier
- Ouamara Nadia
- Ouissa Rachida
- Owyang Clark
- Oziol Eric
- Oâdonnell Max
- Oâhearn Katie
- Oâneil Conar
- Pagadoy MaĂŻder
- Pages Justine
- Palacios Mario
- Palmarini Massimo
- Panarello Giovanna
- Panda Prasan Kumar
- Panda Prasan,
- Panigada Mauro
- Pansu Nathalie
- Papadopoulos Aurélie
- Parra Briseida
- Pasquier Jérémie
- Patauner Fabian
- PatrĂŁo LuĂs
- Paul Christelle
- Paul Mical
- Paulos Jorge
- Paxton William,
- Payen Jean-François
- Pearse India
- Peek Giles,
- Peelman Florent
- Peiffer-Smadja Nathan
- Peigne Vincent
- Pejkovska Mare
- Peltan Ithan,
- Pereira Rui
- Perez Daniel
- Perpoint Thomas
- Perrot Clara Mouton
- Perrot Clara,
- Pesenti Antonio
- PetrouĆĄovĂĄ Lenka
- Petrov-Sanchez Ventzislava
- Peytavin Gilles
- Pharand Scott
- Piagnerelli Michael
- Picard Walter
- Picone Olivier
- Piel-Julian Marie
- Pierobon Carola
- Pimentel Carlos
- Piroth Lionel
- Pius Riinu
- Piva Simone
- Plantier Laurent
- Plotkin Daniel
- Poissy Julien
- Pokorska-Spiewak Maria
- Poli Sergio
- Pollakis Georgios
- Popielska Jolanta
- Postma Douwe,
- Povoa Pedro
- Powis Jeff
- Prapa Sofia
- Prebensen Christian
- Preiser Jean-Charles
- Prestre Vincent
- Price Nicholas
- Prinssen Anton
- Pritchard Mark,
- Proença LĂșcia
- Purcell Gregory
- Puéchal Oriane
- PĂłvoas Diana
- Quesada Luisa
- Quist-Paulsen Else
- Quraishi Mohammed
- Rabaud Christian
- Rafiq Marie
- Ragazzo Gabrielle
- Rainieri Fernando
- Ramakrishnan Nagarajan
- Ramanathan Kollengode
- Rammaert Blandine
- Rapp Christophe
- Rasmin Menaldi
- Rau Cornelius
- Rebaudet Stanislas
- Redl Sarah
- Reeve Brenda
- Rego Caroline Martins
- Rego Caroline,
- Reid Liadain
- Reis Renato
- Remppis Jonathan
- Remy Martine
- Renk Hanna
- Resende Liliana
- Resseguier Anne-Sophie
- Revest Matthieu
- Rewa Oleksa
- Reyes Luis Felipe
- Reyes Luis,
- Ribeiro Ana Freitas
- Ribeiro Ana,
- Richardson David
- Richardson Denise
- Richier Laurent
- Riera Jordi
- Rincon Diego Fernando Bautista
- Rincon Diego,
- Rios Ana LĂșcia
- Rios Ana,
- Rishu Asgar
- Rispal Patrick
- Risso Karine
- Rizer Nicholas
- Roberto André
- Roberts Stephanie
- Robertson David,
- Robineau Olivier
- Roche-Campo Ferran
- Rodari Paola
- Rodeia SimĂŁo
- Roilides Emmanuel
- Rojek Amanda
- Romaru Juliette
- Roncon-Albuquerque Roberto
- Roriz MĂ©lanie
- Rosa-Calatrava Manuel
- Rose Michael
- Rosenberger Dorothea
- Rossanese Andrea
- Rossignol Bénédicte
- Rossignol Patrick
- Roy Carine
- Roze BenoĂźt
- Russell Clark,
- Ryckaert Steffi
- RĂ€tsep Indrek
- Rössler Bernhard
- Saba Isabela
- Sadat Musharaf
- Saidani Nadia
- Salazar Leonardo
- Sales Gabriele
- Sallaberry Stéphane
- Salvator HĂ©lĂšne
- Sanchez Juan Macias
- Sanchez Juan,
- Sanchez Olivier
- Sanchez-Miralles Angel
- Sancho-Shimizu Vanessa
- Sandhu Gyan
- Sandulescu Oana
- Sanharawi Mohammed El
- Sanharawi Mohammed,
- Sant Ceila Maria
- Sant Ceila,
- Santos Marlene
- Santos Marta Leal
- Santos Marta,
- Santos-Olmo Rosario Maria Torres
- Santos-Olmo Rosario,
- Sarfo-Mensah Shirley
- Sarton Benjamine
- Saviciute Egle
- Savvidou Parthena
- Scarsbrook Joshua
- Schermer Tjard
- Scherpereel Arnaud
- Schneider Marion
- Schroll Stephan
- Schwameis Michael
- Scott Janet,
- Scott-Brown James
- Sedillot Nicholas
- Seitz Tamara
- Semaille Caroline
- Semple Malcolm,
- Senneville Eric
- Sequeira Filipa
- Sequeira TĂąnia
- Shadowitz Ellen
- Shamsah Mohammad
- Sharma Pratima
- Shaw Catherine,
- Shaw Victoria
- Shiban Nisreen
- Shime Nobuaki
- Shimizu Hiroaki
- Shimizu Keiki
- Shrapnel Sally
- Shum Hoi Ping
- Shum Hoi,
- Sigfrid Louise
- Silva Catarina
- Silva Maria Joao
- Silva Maria,
- Sin Wai Ching
- Sin Wai,
- Skogen Vegard
- Smith Sue
- Smood Benjamin
- Smyth Michelle
- Snacken Morgane
- So Dominic
- Solis Monserrat
- Solomon Joshua
- Solomon Tom
- Somers Emily
- Sommet AgnĂšs
- Song Myung Jin
- Song Myung,
- Song Rima
- Song Tae
- Sonntagbauer Michael
- Sotomayor Ruth Jimbo
- Sotomayor Ruth,
- Soum Edouard
- Sousa Marta
- Souza-Dantas Vicente
- Sperry Alexandra
- Sriskandan Shiranee
- Staudinger Thomas
- Stecher Stephanie-Susanne
- Stienstra Ymkje
- Stiksrud Birgitte
- Streinu-Cercel Adrian
- Streinu-Cercel Anca
- Strudwick Samantha
- Stuart Ami
- Stuart David
- Suen Jacky,
- Sultana Asfia
- Summers Charlotte
- Svistunov Magdalena SurovcovĂĄ Andrey A.
- Svistunov Magdalena,
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Tabrizi Shirin
- Tagherset Lysa
- Talarek Ewa
- Taleb Sara
- Talsma Jelmer
- Tamlihat Younes Ait
- Tamlihat Younes,
- Tanaka Hiroyuki
- Tanaka Taku
- Taniguchi Hayato
- Tardivon Coralie
- Tattevin Pierre
- Taufik M. Azhari,
- Tedder Richard,
- Teixeira JoĂŁo
- Tellier Marie-Capucine
- Terpstra Pleun
- Terrier Olivier
- Terzi Nicolas
- Tessier-Grenier Hubert
- Thibault V.
- Thiberville Simon-Djamel
- Thill BenoĂźt
- Thompson A.,
- Thompson Shaun
- Thomson David
- Thomson Emma,
- Thuy Duong Bich
- Thuy Duong,
- Thwaites Ryan,
- Timashev Peter,
- Timsit Jean-François
- Toki Maria
- Tonby Kristian
- Torres Antoni
- Torres Margarida
- Trieu Huynh Trung
- Trieu Huynh,
- Trioux Théo
- Tromeur CĂ©cile
- Trontzas Ioannis
- Troost Jonathan
- Trouillon Tiffany
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turtle Lance,
- Tutillo Diego Rolando Morocho
- Tutillo Diego,
- Twardowski Pawel
- Téoulé François
- Uchiyama Makoto
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uva Maria,
- Val-Flores LuĂs
- Van De Velde Stijn
- Van Den Berge Marcel
- Van Der Feltz Machteld
- Van Der Vekens Nicky
- Van Der Voort Peter
- Van Der Werf Sylvie
- Van Dyk Marlice
- Van Gulik Laura
- Van Hattem Jarne
- Van Lelyveld Steven
- Van Netten Carolien
- Van Vinh Chau Nguyen
- Vanel Noémie
- Vanoverschelde Henk
- Vasconcelos Malte Kohns
- Vasconcelos Malte,
- Vauchy Charline
- Vecham Pavan Kumar
- Vecham Pavan,
- Veislinger Aurélie
- Velazco Jorge
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vidal José,
- Vieira CĂ©sar
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Vijayaraghavan Bharath,
- Villanueva Joy Ann
- Villanueva Joy,
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Visseaux Benoit
- Visser Hannah
- Vuorinen Aapeli
- Vuotto Fanny
- Wang Chih-Hsien
- Wei Jia
- Weil Katharina
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wiedemann Aurélie
- Wille Keith
- Wils Evert-Jan
- Xynogalas Ioannis
- Yacoub Sophie
- Yamazaki Masaki
- Yazdanpanah Yazdan
- Yelnik CĂ©cile
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Young Paul
- Yuliarto Saptadi
- Zabbe Marion
- Zacharowski Kai
- Zahran Maram
- Zambon Maria
- Zanella Alberto
- Zawadka Konrad
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60â109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
âTypicalâ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (â€â18 years: 69, 48, 23; 85%), older adults (â„â70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each Pâ<â0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men
ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew Dav
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnal Vanessa
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Auerbach Benjamin
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bacci Cesare
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Bansil Hardeep Si
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro GuimarĂŁes da Costa JoĂŁo
- Barreiro Fernando
- Barros do Vale Maria Alin
- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder S
- Beacham James Bake
- Beattie Michael Da
- Beau Tristan
- Beauchemin Pierre-Hug
- Beccherle Roberto
- Bechtle Philip
- Beck Hans Peter
- Becker Kathrin
- Becker Maurice
- Becker Sebastian
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bee Christophe
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
- Belanger-Champagne Camille
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Garcia Jorge-Arma
- Benjamin Douglas
- Bensinger James
- Bentvelsen Stan
- Beresford Lydia
- Beretta Matteo
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
- Berghaus Frank
- Beringer JĂŒrg
- Bernard Clare
- Bernard Nathan Rog
- Bernius Catrin
- Bernlochner Florian Ur
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertolucci Federico
- Bertsche Carolyn
- Bertsche David
- Besana Maria Ilar
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin Flo
- Besson Nathalie
- Betancourt Christophe
- Bethke Siegfried
- Bevan Adrian Joh
- Bhimji Wahid
- Bianchi Riccardo-M
- Bianchini Louis
- Bianco Michele
- Biebel Otmar
- Biedermann Dustin
- Bieniek Stephen Pa
- Biglietti Michela
- Bilbao De Mendizabal Javier
- Bilokon Halina
- Bindi Marcello
- Binet Sebastien
- Bingul Ahmet
- Bini Cesare
- Biondi Silvia
- Black Curtis
- Black James
- Black Kevin
- Blackburn Daniel
- Blair Robert
- Blanchard Jean-Bapti
- Blanco Jacobo Eze
- Blazek Tomas
- Bloch Ingo
- Blocker Craig
- Blum Walter
- Blumenschein Ulrike
- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona Ser
- Bocci Andrea
- Bock Christophe
- Boehler Michael
- Bogaerts Joannes An
- Bogavac Danijela
- Bogdanchikov Alexander
- Bohm Christian
- Boisvert Veronique
- Bold Tomasz
- Boldea Venera
- Boldyrev Alexey
- Bomben Marco
- Bona Marcella
- Boonekamp Maarten
- Borisov Anatoly
- Borissov Guennadi
- Borroni Sara
- Bortfeldt Jonathan
- Bortolotto Valerio
- Bos Kors
- Boscherini Davide
- Bosman Martine
- Boudreau Joseph
- Bouffard Julian
- Bouhova-Thacker Evelina Va
- Boumediene Djamel Edd
- Bourdarios Claire
- Bousson Nicolas
- Boveia Antonio
- Boyd James
- Boyko Igor
- Bozic Ivan
- Bracinik Juraj
- Brandt Andrew
- Brandt Gerhard
- Brandt Oleg
- Bratzler Uwe
- Brau Benjamin
- Brau James
- Braun Helmut
- Brazzale Simone Fed
- Breaden Madden William Dm
- Brendlinger Kurt
- Brennan Amelia Jea
- Brenner Lydia
- Brenner Richard
- Bressler Shikma
- Bristow Kieran
- Bristow Timothy Mi
- Britton Dave
- Britzger Daniel
- Brochu Frederic
- Brock Ian
- Brock Raymond
- Bronner Johanna
- Brooijmans Gustaaf
- Brooks Timothy
- Brooks William
- Brosamer Jacquelyn
- Brost Elizabeth
- Brown Jonathan
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruneliere Renaud
- Bruni Alessia
- Bruni Graziano
- Bruschi Marco
- Bruscino Nello
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
- Buchholz Peter
- Buckley Andrew
- Buda Stelian Io
- Budagov Ioulian
- Buehrer Felix
- Bugge Lars
- Bugge Magnar Kop
- Bulekov Oleg
- Bullock Daniel
- Burckhart Helfried
- Burdin Sergey
- Burghgrave Blake
- Burke Stephen
- Burmeister Ingo
- Busato Emmanuel
- Bussey Peter
- Butler John
- Butt Aatif Imti
- Buttar Craig
- Butterworth Jonathan
- Butti Pierfrance
- Buttinger William
- Buzatu Adrian
- Buzykaev Aleksey
- BĂŒscher Daniel
- BĂŒscher Volker
- Cabrera UrbĂĄn Susana
- Caforio Davide
- Cairo Valentina
- Cakir Orhan
- Calace Noemi
- Calafiura Paolo
- Calandri Alessandro
- Calderini Giovanni
- Calfayan Philippe
- Caloba Luiz
- Calvet David
- Calvet Samuel
- Camacho Toro Reina
- Camarda Stefano
- Camarri Paolo
- Cameron David
- Caminal Armadans Roger
- Campana Simone
- Campanelli Mario
- Campoverde Angel
- Canale Vincenzo
- Canepa Anadi
- Cano Bret Marc
- Cantero Josu
- Cantrill Robert
- Cao Tingting
- Capeans Garrido Maria Del
- Caprini Irinel
- Caprini Mihai
- Capua Marcella
- Caputo Regina
- Cardarelli Roberto
- Cardillo Fabio
- Carli Tancredi
- Carlino Gianpaolo
- Carminati Leonardo
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German D
- Carter Janet
- Carvalho JoĂŁo
- Casadei Diego
- Casado Maria Pila
- Casolino Mirkoanton
- Castaneda-Miranda Elizabeth
- Castelli Angelanton
- Castillo Gimenez Victoria
- Castro Nuno Filip
- Catastini Pierluigi
- Catinaccio Andrea
- Catmore James
- Cattai Ariella
- Caudron Julien
- Cavaliere Viviana
- Cavalli Donatella
- Cavalli-Sforza Matteo
- Cavasinni Vincenzo
- Ceradini Filippo
- Cerio Benjamin
- Cerny Karel
- Cerri Alessandro
- Cerrito Lucio
- Cerutti Fabio
- Cerv Matevz
- Cervelli Alberto
- Cetin Serkant Al
- Chafaq Aziz
- Chakraborty Dhiman
- Chalupkova Ina
- Chang Philip
- Chapman John Derek
- Charlton Dave
- Chau Chav Chhiv
- Chavez Barajas Carlos Alb
- Cheatham Susan
- Chegwidden Andrew
- Chekanov Sergei
- Chekulaev Sergey
- Chelkov Gueorgui
- Chelstowska Magda Anna
- Chen Chunhui
- Chen Hucheng
- Chen Karen
- Chen Liming
- Chen Shenjian
- Chen Xin
- Chen Ye
- Cheng Hok Chuen
- Cheng Yangyang
- Cheplakov Alexander
- Cheremushkina Evgenia
- Cherkaoui El Moursli Rajaa
- Chernyatin Valeriy
- Cheu Elliott
- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Childers John Taylo
- Chiodini Gabriele
- Chisholm Andrew
- Chislett Rebecca Th
- Chitan Adrian
- Chizhov Mihail
- Choi Kyungeon
- Chouridou Sofia
- Chow Bonnie Kar
- Christodoulou Valentinos
- Chromek-Burckhart Doris
- Chudoba Jiri
- Chuinard Annabelle
- Chwastowski Janusz
- Chytka Ladislav
- Ciapetti Guido
- Ciftci Abbas Kena
- Cinca Diane
- Cindro Vladimir
- Cioara Irina Anto
- Ciocio Alessandra
- Citron Zvi Hirsh
- Ciubancan Mihai
- Clark Allan G
- Clark Brian Lee
- Clark Philip Jam
- Clarke Robert
- Cleland Bill
- Clement Christophe
- Coadou Yann
- Cobal Marina
- Coccaro Andrea
- Cochran James H
- Coffey Laurel
- Cogan Joshua God
- Colasurdo Luca
- Cole Brian
- Cole Stephen
- Colijn Auke-Piete
- Collot Johann
- Colombo Tommaso
- Compostella Gabriele
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon Henr
- Connelly Ian
- Consonni Sofia Mari
- Consorti Valerio
- Constantinescu Serban
- Conta Claudio
- Conti Geraldine
- Conventi Francesco
- Cooke Mark
- Cooper Ben
- Cooper-Sarkar Amanda
- Cornelissen Thijs
- Corradi Massimo
- Corriveau Francois
- Corso-Radu Alina
- Cortes-Gonzalez Arely
- Cortiana Giorgio
- Costa Giuseppe
- Costa MarĂa Jos
- Costanzo Davide
- Cottin Giovanna
- Cowan Glen
- Cox Brian
- Cranmer Kyle
- Cree Graham
- Crescioli Francesco
- Cribbs Wayne Alle
- Crispin Ortuzar Mireia
- Cristinziani Markus
- Croft Vince
- Crosetti Giovanni
- Crépé-Renaudin Sabine
- Cuhadar Donszelmann Tulay
- Cummings Jane
- Curatolo Maria
- Cuthbert Cameron
- Czirr Hendrik
- Czodrowski Patrick
- CÎté David
- D'Auria Saverio
- D'Onofrio Monica
- Da Cunha Sargedas De Sousa Mario Jose
- Da Via Cinzia
- Dabrowski Wladyslaw
- Dafinca Alexandru
- Dai Tiesheng
- Dale Orjan
- Dallaire Frederick
- Dallapiccola Carlo
- Dam Mogens
- Dandoy Jeffrey Ro
- Dang Nguyen Phu
- Daniells Andrew Chr
- Danninger Matthias
- Dano Hoffmann Maria
- Dao Valerio
- Darbo Giovanni
- Darmora Smita
- Dassoulas James
- Dattagupta Aparajita
- Davey Will
- David Claire
- Davidek Tomas
- Davies Eleanor
- Davies Merlin
- Davison Peter
- Davygora Yuriy
- Dawe Edmund
- Dawson Ian
- Daya-Ishmukhametova Rozmin
- de Asmundis Riccardo
- De Benedetti Abraham
- De Castro Stefano
- De Cecco Sandro
- De Groot Nicolo
- de Jong Paul
- De la Torre Hector
- De Lorenzi Francesco
- De Nooij Lucie
- De Pedis Daniele
- De Salvo Alessandro
- De Sanctis Umberto
- De Santo Antonella
- De Vivie De Regie Jean-Bapti
- De Kaushik
- Dearnaley William Ja
- Debbe Ramiro
- Debenedetti Chiara
- Dedovich Dmitri
- Deigaard Ingrid
- Del Peso Jose
- Del Prete Tarcisio
- Delgove David
- Deliot Frederic
- Delitzsch Chris Male
- Deliyergiyev Maksym
- Dell'Acqua Andrea
- Dell'Asta Lidia
- Dell'Orso Mauro
- Della Pietra Massimo
- della Volpe Domenico
- Delmastro Marco
- Delsart Pierre-Ant
- Deluca Carolina
- DeMarco David
- Demers Sarah
- Demichev Mikhail
- Demilly Aurelien
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- Edson William
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- Eifert Till
- Eigen Gerald
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- Hernåndez Jiménez Yesenia
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- Karastathis Nikolaos
- Kareem Mohammad J
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- Keoshkerian Houry
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- Weingarten Jens
- Weiser Christian
- Weits Hartger
- Wells Phillippa
- Wenaus Torre
- Wengler Thorsten
- Wenig Siegfried
- Wermes Norbert
- Werner Matthias
- Werner Per
- Wessels Martin
- Wetter Jeffrey
- Whalen Kathleen
- Wharton Andrew Mar
- White Andrew
- White Martin
- White Ryan
- White Sebastian
- Whiteson Daniel
- Wickens Fred
- Wiedenmann Werner
- Wielers Monika
- Wienemann Peter
- Wiglesworth Craig
- Wiik-Fuchs Liv Antje
- Wildauer Andreas
- Wilkens Henric Geo
- Williams Hugh
- Williams Sarah
- Willis Christophe
- Willocq Stephane
- Wilson Alan
- Wilson John
- Wingerter-Seez Isabelle
- Winklmeier Frank
- Winter Benedict T
- Wittgen Matthias
- Wittkowski Josephine
- Wollstadt Simon Jako
- Wolter Marcin Wla
- Wolters Helmut
- Wosiek Barbara
- Wotschack Jorg
- Woudstra Martin
- Wozniak Krzysztof
- Wu Mengqing
- Wu Miles
- Wu Sau Lan
- Wu Xin
- Wu Yusheng
- Wyatt Terry Rich
- Wynne Benjamin
- Xella Stefania
- Xu Da
- Xu Lailin
- Yabsley Bruce
- Yacoob Sahal
- Yakabe Ryota
- Yamada Miho
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yao Weiming
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Ă kesson Torsten Pa
- Ă sman Barbro
- ĆœeniĆĄ Tibor
- ĆœivkoviÄ Lidija
- Îlvarez Piqueras DamiĂĄn
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 29/10/2015
- Field of study
Measurement of inclusive jet charged-particle fragmentation functions in Pb plus Pb collisions at root S-NN=2.76 TeV with the ATLAS detector
- Author
- \u17deni\u161 T.
- \uc5kesson T. P. A.
- \uc5sman B.
- Aad G.
- Abbott B.
- Abdallah J.
- Abdel Khalek S.
- Abdinov O.
- Aben R.
- Abi B.
- Abolins M.
- Abouzeid O. S.
- Abramowicz H.
- Abreu H.
- Abreu R.
- Abulaiti Y.
- Acharya B. S.
- Adamczyk L.
- Adams D. L.
- Adelman J.
- Adomeit S.
- Adye T.
- Agatonovic Jovin T.
- Aguilar Saavedra J. A.
- Agustoni M.
- Ahlen S. P.
- Ahmadov F.
- Aielli G.
- Akerstedt H.
- Akimoto G.
- Akimov A. V.
- Alberghi G. L.
- Albert J.
- Albrand S.
- Alconada Verzini M. J.
- Aleksa M.
- Aleksandrov I. N.
- Alexa C.
- Alexander G.
- Alexandre G.
- Alexopoulos T.
- Alhroob M.
- Alimonti G.
- Alio L.
- Alison J.
- Allbrooke B. M. M.
- Allison L. J.
- Allport P. P.
- Almond J.
- Aloisio A.
- Alonso A.
- Alonso F.
- Alpigiani C.
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- Amelung C.
- Amidei D.
- Amor Dos Santos S. P.
- Amorim A.
- Amoroso S.
- Amram N.
- Amundsen G.
- Anastopoulos C.
- Ancu L. S.
- Andari N.
- Andeen T.
- Anders C. F.
- Anders G.
- Anderson K. J.
- Andreazza A.
- Andrei V.
- Anduaga X. S.
- Angelidakis S.
- Angelozzi I.
- Anger P.
- Angerami A.
- Anghinolfi F.
- Anisenkov A. V.
- Anjos N.
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- Chalupkova I.
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- Cheplakov A.
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- Chernyatin V.
- Cheu E.
- Chevalier L.
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- Publication date
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- Field of study
© 2014 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/license/by/3.0/). Funded by SCOAP3
DUX4 induces a transcriptome more characteristic of a less-differentiated cell state and inhibits myogenesis
- Author
- Publication venue
- 'The Company of Biologists'
- Publication date
- 01/10/2016
- Field of study
Neurological Motor Disorder
Expression Profiling-Based Subtyping Identifies Novel Non-small Cell Lung Cancer Subgroups and Implicates Putative Resistance to Pemetrexed Therapy
- Author
- Anbazhagan
- Bepler
- Bertino
- Bhattacharjee
- Bianca den Hamer
- Bild
- Borczuk
- Ceppi
- Ceppi
- Ciuleanu
- Esteban
- Fan
- Finnegan
- Frank Grosveld
- Garber
- Giovannetti
- Golub
- Gronberg
- Gustafsson
- Hanauske
- Hanauske
- Henk C. Hoogsteden
- Inamura
- Jackman
- Joachim Aerts
- Joost Hegmans
- Jun Hou
- Koscielny
- Li
- Longo-Sorbello
- Margaretha Lambers
- Michael A. den Bakker
- Monica
- Moreira
- Parker
- Perou
- Raponi
- Righi
- Rosell
- Scagliotti
- Scagliotti
- Scagliotti
- Shukuya
- Sjaak Philipsen
- Subramanian
- Sun
- Takeuchi
- Tibshirani
- Travis
- Tubbs
- Tusher
- Wigle
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- Field of study