377 research outputs found
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
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- Abulaiti Y
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- Achkar B
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- Stevenson TJ
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- Sumida T
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- Suster CJE
- Sutton MR
- Suzuki S
- Svatos M
- Swiatlowski M
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- Swirski T
- Sydorenko A
- Sykora I
- Sykora M
- Sykora T
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- Taenzer J
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- Taylor AJ
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- Teuscher RJ
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- Theveneaux-Pelzer T
- Thiele F
- Thomas DW
- Thomas JO
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- Thompson PD
- Thomsen LA
- Thomson E
- Thorpe EJ
- Tikhomirov VO
- Tikhonov YA
- Timoshenko S
- Tipton P
- Tisserant S
- Tobon CAM
- Todome K
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- Tsirigotis A
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- Tsukerman II
- Tsulaia V
- Tsuno S
- Tsybychev D
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- Tudorache A
- Tudorache V
- Tulbure TT
- Tuna AN
- Turchikhin S
- Turgeman D
- Turner RJ
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- Urban J
- Urquijo P
- Usai G
- Uysal Z
- Vacek V
- Vachon B
- Vadla KOH
- Vaidya A
- Valderanis C
- Vale MAB
- Valente M
- Valentinetti S
- Valero A
- Valery L
- Vallance RA
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- Van Vulpen I
- Vanadia M
- Vandelli W
- Vandenbroucke M
- Vandewall ER
- Vaniachine A
- Vannicola D
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- Varnes EW
- Varni C
- Varol T
- Varouchas D
- Varvell KE
- Vasile ME
- Vasquez GA
- Vazeille F
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- Vazquez CJB
- Vazquez JGP
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- Veloce LM
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- Verducci M
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- Vermeulen JC
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- Vetterli MC
- Viaux Maira N
- Vickey T
- Viehhauser GHA
- Vigani L
- Villa M
- Vilucchi E
- Vincter MG
- Virdee GS
- Vishwakarma A
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- Vokac P
- von Buddenbrock SE
- Von Toerne E
- Vorobel V
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- Vos M
- Vossebeld JH
- Vozak M
- Vranjes N
- Vrba V
- Vreeswijk M
- Vuillermet R
- Vukotic I
- Wagner P
- Wagner W
- Wagner-Kuhr J
- Wahdan S
- Wahlberg H
- Walbrecht VM
- Walder J
- Walker R
- Walker SD
- Walkowiak W
- Wallangen V
- Wang AM
- Wang AZ
- Wang C
- Wang F
- Wang H
- Wang J
- Wang P
- Wang Q
- Wang R
- Wang R-J
- Wang SM
- Wang W
- Wang WT
- Wang WX
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- Wang Z
- Wanotayaroj C
- Warburton A
- Ward CP
- Wardrope DR
- Warrack N
- Washbrook A
- Watson AT
- Watson MF
- Watts G
- Waugh BM
- Webb AF
- Webb S
- Weber C
- Weber MS
- Weber SA
- Weber SM
- Weidberg AR
- Weingarten J
- Weirich M
- Weiser C
- Wells PS
- Wenaus T
- Wengler T
- Wenig S
- Wermes N
- Werner MD
- Wessels M
- Weston TD
- Whalen K
- Whallon NL
- Wharton AM
- White A
- White AS
- White MJ
- Whiteson D
- Whitmore BW
- Wiedenmann W
- Wiel C
- Wielers M
- Wieseotte N
- Wiglesworth C
- Wiik-Fuchs LAM
- Wilkens HG
- Wilkins LJ
- Williams HH
- Williams S
- Willis C
- Willocq S
- Wingerter-Seez I
- Winkels E
- Winklmeier F
- Winston OJ
- Winter BT
- Wittgen M
- Wobisch M
- Wolf A
- Wolf TMH
- Wolff R
- Wolker R
- Wollrath J
- Wolter MW
- Wolters H
- Wong VWS
- Woods NL
- Worm SD
- Wosiek BK
- Wozniak KW
- Wraight K
- Wu SL
- Wu X
- Wu Y
- Wyatt TR
- Wynne BM
- Xella S
- Xi Z
- Xia L
- Xiao X
- Xiotidis I
- Xu D
- Xu H
- Xu L
- Xu T
- Xu W
- Xu Z
- Yabsley B
- Yacoob S
- Yajima K
- Yallup DP
- Yamaguchi N
- Yamaguchi Y
- Yamamoto A
- Yamatani M
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang HJ
- Yang HT
- Yang S
- Yang T
- Yang X
- Yang Y
- Yao W-M
- Yap YC
- Yasu Y
- Yatsenko E
- Ye H
- Ye J
- Ye S
- Yeletskikh I
- Yexley MR
- Yigitbasi E
- Yildiz HD
- Yorita K
- Yoshihara K
- Young C
- Young CJS
- Yu J
- Yuan R
- Yue X
- Zaazoua M
- Zabinski B
- Zacharis G
- Zaffaroni E
- Zahreddine J
- Zaitsev AM
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zanzi D
- Zaripovas DR
- Zeissner S
- Zeitnitz C
- Zemaityte G
- Zeng JC
- Zenin O
- Zenis T
- Zerwas D
- Zgubic M
- Zhang B
- Zhang DF
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang M
- Zhang R
- Zhang S
- Zhang X
- Zhang Y
- Zhang Z
- Zhao P
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
- Zhou MS
- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine N
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Pathways between Primary Production and Fisheries Yields of Large Marine Ecosystems
- Author
- A Morel
- AF Michaels
- AG Hirst
- B Hansen
- BA Megrey
- BT Hargrave
- Burton V. Shank
- C Stock
- CA Stock
- Charles Stock
- Cynthia H. Pilskaln
- D Pauly
- D Pauly
- D Roemmich
- D Simberloff
- DH Cushing
- DJ Agnew
- DM Ware
- DM Ware
- E Chassot
- E Chassot
- E Houde
- E Jeppesen
- E Marquis
- EA Laws
- ED Houde
- EE Werner
- EK Pikitch
- HU Sverdrup
- J Campbell
- J Gavis
- JA Downing
- Jason S. Link
- JE Bissinger
- JE Cloern
- JH Ryther
- JM Melack
- JM Rose
- JP Dunne
- JS Collie
- JS Link
- JS Link
- Julie M. Rose
- K Sherman
- Kenneth F. Drinkwater
- Kevin D. Friedland
- KM Brander
- Konstantinos I. Stergiou
- KT Frank
- L Conti
- L Legendre
- LP Garrison
- MAM Friedrichs
- ME Carr
- ME Huntley
- Michael J. Fogarty
- MJ Behrenfeld
- R Jones
- R Margalef
- R Watson
- R Wehrens
- RA Armstrong
- RA Myers
- RL Iverson
- RO Ramseier
- Robert T. Leaf
- RR Sokal
- RT Oglesby
- RW Eppley
- RW Eppley
- RW Reynolds
- S Gaichas
- S Libralato
- S Sathyendranath
- ST Ross
- SW Nixon
- T Kiorboe
- TD O'Brien
- VS Saba
- X Irigoien
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
The shift in marine resource management from a compartmentalized approach of dealing with resources on a species basis to an approach based on management of spatially defined ecosystems requires an accurate accounting of energy flow. The flow of energy from primary production through the food web will ultimately limit upper trophic-level fishery yields. In this work, we examine the relationship between yield and several metrics including net primary production, chlorophyll concentration, particle-export ratio, and the ratio of secondary to primary production. We also evaluate the relationship between yield and two additional rate measures that describe the export of energy from the pelagic food web, particle export flux and mesozooplankton productivity. We found primary production is a poor predictor of global fishery yields for a sample of 52 large marine ecosystems. However, chlorophyll concentration, particle-export ratio, and the ratio of secondary to primary production were positively associated with yields. The latter two measures provide greater mechanistic insight into factors controlling fishery production than chlorophyll concentration alone. Particle export flux and mesozooplankton productivity were also significantly related to yield on a global basis. Collectively, our analyses suggest that factors related to the export of energy from pelagic food webs are critical to defining patterns of fishery yields. Such trophic patterns are associated with temperature and latitude and hence greater yields are associated with colder, high latitude ecosystems
Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial.
- Author
- A Sarah Walker
- Abid Hussain
- Abiola Alli
- Abraham Gihawi
- Achyut Guleri
- Achyut Guleri
- Adam Jeans
- Adam Lewszuk
- Adam Mohamoodally
- Adam Wolstencroft
- Adele Marshall
- Adetunji Adedayo
- Adrian Lyons
- Agnieszka Skotnicka
- Ahalya Malachira
- Aiden Plant
- Alaric Colville
- Alex Chrdle
- Alex Peel
- Alex Szubert
- Alexander Szubert
- Ali Vaughn
- Alisha Beddoe
- Alison Eyre
- Alison Fair
- Alison Porges
- Alison Potter
- Alison Stolton
- Amanda Fife
- Amanda Moran
- Amandip Sahota
- Amita Patel
- Amy Driffill
- Amy Janvier
- Amy Murray
- Ana de Veciana
- Andrea Boyce
- Andree Evans
- Andrew Conbeer
- Andrew Flatt
- Andrew Potter
- Andrew Rosser
- Angela Cape
- Angela Dunne
- Angela Houston
- Angela King
- Angela McCadden
- Angela Parkin
- Ann Sarah Walker
- Anna L Goodman
- Anna McSkeane
- Anna Reyes
- Anna Sweeney
- Anne Anderson
- Anne Clarke
- Anthony Donnelly
- Antonia Scobie
- Antonio Querol-Rubiera
- Aodhan Breathnach
- Asha Mathews
- Atul Kotecha
- Avril Masdin
- Ayodele Ajayi
- Bala Subramanian
- Belinda Romans
- Ben Marks
- Benjamin Jeffs
- Bernadette Cook
- Bernadette Young
- Bernadette Young
- Bev Warner
- Bijal Patel
- Boingotlo Masake
- Brooke Jackson
- Cariad Evan
- Carlene Rowson
- Carlos Díaz-Montaña
- Carmen Cantell
- Carol Brooks
- Carole McPherson
- Caroline Andrews
- Caroline Bedford
- Caroline Renton
- Carolyn Hemsley
- Carrie Ridley
- Catherine Aldridge
- Charley Higham
- Charlote Armer
- Charlotte Eglinton
- Charlotte Gibbs
- Charlotte Russell
- Cherrelle de Souza
- Cheryl Bailey
- Chi Kai Tam
- Chi Kai Tam
- Chiara Borg
- Chris Brewer
- Chris Smalley
- Christop Lohan
- Christopher Sim
- Claire Keatley
- Claire Williams
- Clare Hamson
- Clare Hutchison
- Clare James
- Clare Tarbotton
- Clive Graham
- Clive Graham
- Colin Brown
- Colin Walker
- Cordelia Watson
- Cressida Auckland
- Cressida Auckland
- Cristina Suarez
- Dai Griffiths
- Dakshika Jeyaratnam
- Dakshika Jeyaratnam
- Damien Mack
- Damilola Otiko
- Daniel Greaves
- Daniela Shackcloth
- Dave Osborne
- David A Price
- David Ashley Price
- David Chadwick
- David Harvey
- David Harvey
- Debbie Johnson
- Deborah Gilliam
- Deepa Nayar
- Denise Ward
- Denise Ward
- Diane Swift
- Dominika Wlazly
- Donna Palmer
- Duncan Wyncoll
- Ed Moran
- Edmund Ong
- Efisia Sais
- Elaine Strachan
- Elen Witness
- Elian Liu
- Elizabeth Foote
- Elizabeth Woodford
- Ella Foncel
- Ellen Adams
- Emily Hetherington
- Emma Folland
- Emma Foreman
- Emma Lawrence
- Emma Moore
- Emmanuel Nsutebu
- Emmanuel Nsutebu
- Faith Okhuoya
- Fiona Walters
- Fleur Hudson
- Fleur Hudson
- Fozia Ahmad
- Gagan Kaler
- Gavin Barlow
- Gavin Barlow
- Gaynor Notcheva
- Gayti Islam
- Gemma Pill
- Geoffrey Howell
- Georgina Shaw
- Giordana Sorrentino
- Gonzalez-Ruiz Armando
- Graham FitzGerald
- Gus Cardoso
- Guy E Thwaites
- Guy Thwaites
- Hannah Allsop
- Hannah Crowther
- Hannah Gott
- Helen Chesterfield
- Helen Fairlamb
- Helen Preedy
- Helen Reynolds
- Helen Vassallo
- Helen Webb
- Helen Wilson
- Helen Winslow
- Helen Wooldridge
- Helena Bond
- Helena White
- Hesther Wilson
- Hezron Greaves
- Hilary Pateman
- Holly Burton
- Ilias Mariolis
- Ines De Abreu
- Ingrid Emmerson
- Isobel Ramsay
- Jack Briggs
- Jackie Westcott
- James Calderwood
- James Fellows
- James Meiring
- James Millard
- James Price
- Jane Cunningham
- Jane Minton
- Jane Minton
- Jane Thompson
- Janet Andrews
- Janet Cairns
- Janet Cairns
- Janet Middle
- Janine Gradwell
- Jason Biswas
- Jason Howard
- Jason Wong
- Jennifer Fitzpatrick
- Jennifer Fitzpatrick
- Jennifer Harrison
- Jess Mandiza
- Jill Deane
- Jill Lyons
- Jim Anson
- Jo Studham
- Joanna Allen
- Joanna Flanagan
- Joanne Gordon
- Joanne Malkin
- Joanne Thorpe
- Joanne Williams
- Joby Cole
- John Humphries
- John Paul
- John Sloss
- John Widdrington
- John Williams
- John Williams
- Jonathan D Edgeworth
- Jonathan D Edgeworth
- Jonathan Folb
- Jonathan Wilson
- Jordan Ewing
- Joseph Lewis
- Josephine Marange
- Judith Chapman
- Judith Platt
- Judy Sercombe
- Julia Greig
- Julia Greig
- Julia Halpin
- Julian Sutton
- Julian Sutton
- Julie Frudd
- Julie Mitchell
- Julie Sorrell
- Karen Bisnauthsing
- Karen Brookes
- Karen Martin
- Kate Ellis
- Kate Maitland
- Kate Maloney
- Kate Ripalda
- Katherine Cullen
- Katherine Curley
- Katherine Pagett
- Kathryn Birchall
- Kathryn Louise Taylor
- Kathryn Potts
- Katie Wilkins
- Katy Marden
- Katy Moore
- Keith Yip
- Kelly Attack
- Kevin Cole
- Kim Cox
- Kim Ryalls
- Kirandip Mandar
- Kirsty Baillie
- Kirsty Gladas
- Kristian Warnes
- Kristine Criste
- Laura Behar
- Laura Butland
- Laura Latter
- Laura Makey
- Laura O'Neil
- Laura Ortiz-Ruiz de Gordoa
- Laura Shewan
- Laura Watson
- Leanne Carwithen
- Leanne Galloway-Browne
- Leila Bahadur
- Lemonia Ftika
- Lenka Strakova
- Leon Peto
- Leona Trainor
- Leona Yabsley
- Lesley Rigden
- Leslie Masters
- Lewis Jones
- Li-An Brown
- Lillian Tsang
- Linda March
- Lindsey Masters
- Lisa Burgess
- Lisa Hurley
- Lizzie Roberts
- Lois Mlemba
- Louise Barrett
- Louise Robinson
- Louise Wright
- Luis Cotter
- Luke Anson
- Luke Bedford
- Lydia Rylance-Knight
- Lynne Smart
- Lynne Whitehead
- Lynsey Goodwin
- Lynsey Stephenson
- M Estee Török
- M Estée Török
- Maggie Cole
- Maggie Kalita
- Manish Pareek
- Manju Joy
- Manuel Fenech
- Maria Edwards
- Maria Hayes
- Maria Nadolski
- Marie-Claire Hoyle
- Marie-Claire West
- Marina Morgan
- Mark Bolton
- Mark Wallis
- Martin J Llewelyn
- Martin Llewelyn
- Martin Wiselka
- Martin Wiselka
- Martyn Cain
- Mary Wands
- Matthew Scarborough
- Matthew Scarborough
- Maxine Hough
- Mazhar Alam
- Mel Baxter
- Melanie Ekani
- Melanie Harrison
- Melanie Hutchings
- Melinda Munang
- Melody Smith
- Michael Ankcorn
- Michelle A Graver
- Michelle Wood
- Mike Marner
- Miranda Kean
- Mirriam Sangombe
- Muge Cevik
- Musa Kamfose
- N Claire Gordon
- Nadine Abberley
- Natalia Waddington
- Naval Vyse
- Neil Jenkins
- Neil Jenkins
- Neil Stone
- Nicholas Beeching
- Nicola Claire Gordon
- Nicola Ridley
- Nicola Smith
- Nicolas Cortes
- Nisa Khan
- Noah Yogo
- Orla Brady
- Pankaj Lal
- Pankaj Lal
- Paul Chadwick
- Paul Jones
- Paul McWhinney
- Paul McWhinney
- Paul R Chadwick
- Paul Roberts
- Paula Harlow
- Paula Sharratt
- Pauline Lambert
- Pavithra Natarajan
- Peter Flegg
- Peter Moss
- Peter Wilson
- Peter Wilson
- Polly Tarrant
- Rachel Abrahams
- Rachel Austin-Hutchison
- Rachel Bousfield
- Rachel Vincent
- Rahul Kurup
- Rajesh Jarghese
- Rakhee Chahuan
- Rasha Said
- Rashmi Sharma
- Rebecca B Saunderson
- Rebecca Palmer
- Rebecca Tagney
- Rebecca Warren
- Reni Jacob
- Richard Bellamy
- Richard Cunningham
- Richard Nendick
- Rob Porter
- Rob Wosley
- Robert Porter
- Robert Reed
- Robert Tilley
- Robert Tilley
- Roderick Balancio-Tolentino
- Rosie Fok
- Rosie Fok
- Ruth Millett
- Ruth Moroney
- Saadia Rahman
- Saba Qaiser
- Sally Batham
- Samantha Crossman
- Sani Aliyu
- Sanuki Perera
- Sara Taiyari
- Sarah A Wyllie
- Sarah Birchall
- Sarah Dyas
- Sarah Glover
- Sarah Meisner
- Sarah Meisner
- Sarah Moll
- Sarah Rippon
- Sarah Stevenson
- Sarah Thornthwaite
- Sarah Wyllie
- Scott Prentice
- Sebastien Martin
- Senait Haile
- Sephora Shaw
- Sergio Muñoz-Villaverde
- Sharon Sheehan
- Shirley Cooper
- Shirley Todd
- Shona Hughes
- Simon Matthews
- Simon Warren
- Sophie Collier
- Sophie Whiteley
- Stacey Donaldson
- Stacey Valentine
- Stephen Booth
- Stephen Coleman
- Stephen K Glass
- Stephen Mepham
- Stephen Morris-Jones
- Sue Kimachia
- Sue Williams
- Suryabrata Banerjee
- Susan Hopkins
- Susan Hopkins
- Susan Lord
- Suzanne Price
- Tamara Mitchell
- Tamika Chapter
- Tat Yam
- Tenessa Sargent
- Teresa Pettifer
- Theodore Gouliouris
- Tim Kemp
- Tim Planche
- Tim Planche
- Tina Burdett
- Tiphanie Clarke
- Tracey Dobson
- Tracey Mynes
- Tracey Platt
- Tracy Matheson-Smith
- Tristan Clark
- Una Poultney
- Veena Raviprakash
- Veenu Kollipara
- Vicki Lowthorpe
- Vicky Chu
- Victoria Dean
- Vusumuzi Shabangu
- Weronika Szypura
- Yvonne Jackson
- Zaheer Islam
- Zoe Martin
- Zoe Prime
- Zoe Swann
- Publication venue
- Lancet
- Publication date
- 14/12/2017
- Field of study
BACKGROUND: Staphylococcus aureus bacteraemia is a common cause of severe community-acquired and hospital-acquired infection worldwide. We tested the hypothesis that adjunctive rifampicin would reduce bacteriologically confirmed treatment failure or disease recurrence, or death, by enhancing early S aureus killing, sterilising infected foci and blood faster, and reducing risks of dissemination and metastatic infection. METHODS: In this multicentre, randomised, double-blind, placebo-controlled trial, adults (≥18 years) with S aureus bacteraemia who had received ≤96 h of active antibiotic therapy were recruited from 29 UK hospitals. Patients were randomly assigned (1:1) via a computer-generated sequential randomisation list to receive 2 weeks of adjunctive rifampicin (600 mg or 900 mg per day according to weight, oral or intravenous) versus identical placebo, together with standard antibiotic therapy. Randomisation was stratified by centre. Patients, investigators, and those caring for the patients were masked to group allocation. The primary outcome was time to bacteriologically confirmed treatment failure or disease recurrence, or death (all-cause), from randomisation to 12 weeks, adjudicated by an independent review committee masked to the treatment. Analysis was intention to treat. This trial was registered, number ISRCTN37666216, and is closed to new participants. FINDINGS: Between Dec 10, 2012, and Oct 25, 2016, 758 eligible participants were randomly assigned: 370 to rifampicin and 388 to placebo. 485 (64%) participants had community-acquired S aureus infections, and 132 (17%) had nosocomial S aureus infections. 47 (6%) had meticillin-resistant infections. 301 (40%) participants had an initial deep infection focus. Standard antibiotics were given for 29 (IQR 18-45) days; 619 (82%) participants received flucloxacillin. By week 12, 62 (17%) of participants who received rifampicin versus 71 (18%) who received placebo experienced treatment failure or disease recurrence, or died (absolute risk difference -1·4%, 95% CI -7·0 to 4·3; hazard ratio 0·96, 0·68-1·35, p=0·81). From randomisation to 12 weeks, no evidence of differences in serious (p=0·17) or grade 3-4 (p=0·36) adverse events were observed; however, 63 (17%) participants in the rifampicin group versus 39 (10%) in the placebo group had antibiotic or trial drug-modifying adverse events (p=0·004), and 24 (6%) versus six (2%) had drug interactions (p=0·0005). INTERPRETATION: Adjunctive rifampicin provided no overall benefit over standard antibiotic therapy in adults with S aureus bacteraemia. FUNDING: UK National Institute for Health Research Health Technology Assessment
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- Author
- A Abbate
- A Abhyankar
- A Adams
- A Agafina
- A Akyea-Djamson
- A Alan
- A Alfieri
- A Alfrey
- A Alvarisqueta
- A Amos
- A Anadiotis
- A Anneveldt
- A Antolick
- A Arthur
- A Aslam
- Abaci F
- Abdullakutty J
- Abhaichand R
- Abib E Jr
- Aboufakher R
- Abrantes J
- Abreu M
- Abulencia K
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- Acampora M
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- Acevedo B
- Acevedo L
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- Adams M
- Adjic Nc
- Affaki Gs
- Agarwal Dk
- Aggarwal Rk
- Agosta Gf
- Aguilar M
- Aguilar M
- Ahire N
- Ahmad I
- Ahmed Sh
- Ahn Y
- Aish B
- Aiub F
- Aiub J
- Ajax K
- Ajioka M
- Akai Y
- Akatova E
- Akrap B
- Al Joundi T
- Al-Khalili F
- Albisu J
- Alcalde Jm
- Alcide P
- Alfonso T
- Allen J
- Alllison Dc
- Almaliky T
- Amerena J
- Andersen K
- Andor M
- Angelova I
- Angiolillo D
- Anita S
- Anker Sd
- Antalik L
- Antonicelli R
- Aparicio Cv
- Apel T
- Apostolovic S
- Ara M
- Aragorn L
- Arango Jl
- Araujo Fonseca M
- Ardissino D
- Arenas Leon Jl
- Arevalo S
- Argiolas G
- Arif I
- Armas E
- Aron G
- Arora S
- Asafu-Adjaye N
- Ashcom T
- Ashford M
- Ashino K
- Asim Oktay Ao
- Assarsson E
- Ata B
- Ather N
- Atieh M
- Aull L
- Avalos V
- Avdonina N
- Awasthi Ak
- Axthelm C
- Ayala M
- Ayasse D
- Ayasse M
- Azizad M
- Azize Gm
- B Becker
- Baar M
- Babu R
- Backer T
- Badea C
- Baden M
- Baehl S
- Baek C
- Baeumer A
- Bagi Es
- Bai A
- Bailey K
- Bailey S
- Bair S
- Baker A
- Baker C
- Bakhai A
- Bakker H
- Baksi A
- Baldin Mg
- Bali Hk
- Ballantyne C
- Ballmajo M
- Balode A
- Balukova E
- Bang Sa
- Banker D
- Banker K
- Baquero A
- Barbarash Ol
- Barbato E
- Barbosa E
- Barnett S
- Baron S
- Barreto M
- Barroso A
- Barroso W
- Bartkowiak A
- Bartosh L
- Bartuseviciene S
- Bashir K
- Baszak J
- Bata Ir
- Bayram E
- Beall K
- Beaudry M
- Beauregard La
- Beckett L
- Belejchak P
- Belle Isle J
- Belohlavek J
- Bendelow T
- Bender D
- Benedetti G
- Benjamin S
- Benton J
- Berdoff R
- Berger V
- Bergeron P
- Bergholtz T
- Bergler-Klein J
- Berk M
- Berli Ma
- Bernstein M
- Berra Fc
- Berti S
- Berulfsen A
- Bevilacqua Mt
- Bhadade S
- Bilazarian S
- Bilodeau N
- Binder A
- Binns Y
- Birdane A
- Bisne V
- Bitzer V
- Blagdon M
- Blahey M
- Blankenberg S
- Blazsek Z
- Bloch S
- Blom Kb
- Bluemel J
- Blumberg C
- Blumenthal R
- Bocanera M
- Bodanese L
- Boffetti P
- Bohra P
- Bohula E
- Boivin Mc
- Bolduc H
- Boley K
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- Bolsmann C
- Boman K
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- Borrayo Na
- Boström På
- Botelho R
- Botta C
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- Boulanger K
- Bourgeois S
- Bouvy C
- Bowen L
- Boyarkin M
- Bradley A
- Brady L
- Bramlet D
- Brath H
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- Brickman T
- Briggs S
- Briké C
- Brodmann M
- Brons S
- Brousalis L
- Brouwer M
- Brown C
- Brown N
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- Buchannan C
- Budaj A
- Budassi N
- Budkova J
- Bugan V
- Buhlman S
- Bulashova O
- Bunschoten P
- Burke W
- Burley T
- Burova N
- Burris H
- Burton C
- Burton J
- Burton M
- Burtt D
- Busak L
- Busic N
- Byars W
- Bøen Rh
- C Clavier-Firmin
- C Conradie
- C Contzen
- C Cotes
- C Covert
- C Cuneo
- Caballero-Valiente B
- Cabau Jr
- Calabrese A
- Campanale Eg
- Candusso R
- Cantor W
- CANTOS Trial Group. Krum H
- Capova L
- Carabajal T
- Carr K
- Carrillo J
- Caruso G
- Casala J
- Caso P
- Casoinic F
- Castillo J
- Castillo T
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- Cerda L
- Cermak O
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- Chaggar S
- Chambers J
- Chamblee T
- Chang K
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- Chang Wh
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- Chattin W
- Chauhan D
- Chauhan H
- Chaussé I
- Chavada J
- Chaverra I
- Chaware G
- Chee L
- Chella S
- Chen Cp
- Chen J
- Chen Mh
- Chen Y
- Chen Yc
- Chen Zc
- Cheng Jj
- Cheng S
- Cheng Sm
- Cherlin R
- Cheung D
- Chhabra A
- Chintala P
- Chiodi L
- Choi Aj
- Chou S
- Chouinard G
- Christensen L
- Christenson S
- Chung A
- Churina S
- Cifkova R
- Ciglenecki N
- Cioffi A
- Cislowski D
- Cleveland T
- Clocotan M
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- Colfer H
- Colhoun H
- Collier D
- Collins R
- Coloma G
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- Colvin T
- Coman S
- Commerford P
- Commerford P
- Conrado Y
- Cools F
- Cornel Jh
- Corona V
- Coronel J
- Cosgrove N
- Cosgrove S
- Cosmi F
- Costa Amorim R
- Coufalova Z
- Covell W
- Cox B
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- Craig W
- Crandall L
- Crawford G
- Crea F
- Crepps K
- Crocamo A
- Cromer M
- Cruz H
- Cruz H
- Cruz M
- Csala L
- Cucher F
- Cuentas I
- Cuervo A
- Curiac D
- Cymerman K
- Cyprian R
- Czerski T
- D'Amours Dg
- D Dash
- D Dattani
- D Denham
- D Desai
- D Desalle
- D Digangi
- D Dunn
- Da Costa F
- Da Silva A
- Da Silva D Jr
- Da Silva O Jr
- Dahlen G
- Dalseg Am
- Damron M
- Danik J
- Davalos C
- Dave B
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- Dawood Sy
- Dayer M
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- De Caterina R
- De Jong C
- De Knijf K
- De Krumbach L
- De Los Milagros Had M
- De Los Rios M
- De Rosa S
- De Vos A
- De Wolf L
- Dean J
- Debnam S
- Decsi K
- Decsi Kl
- Dedek V
- Dedkova S
- Defosse C
- Degennaro N
- Dehning M
- Dela Llana A
- Delfonso F
- Delforge M
- Delgadillo T
- Dellasa M
- Dellborg M
- Dellorso M
- Demidova M
- Den Hartog F
- Denecke C
- Dengler T
- Dermitzakis A
- Deslongchamps F
- Dessalvi Cc
- Destro M
- Dettmer M
- Devasia T
- Deweerdt N
- Dhanak R
- Dhawan M
- Di Biase M
- Diago M
- Diaz M
- Dicken T
- Dickstein K
- Diederich C
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- Diehl R
- Diller P
- Dimattia M
- Dimitrov G
- Diodati J
- Dobariya H
- Dobilas V
- Dodds G
- Doesborg L
- Doggett J
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- Dommerholt R
- Donahue K
- Donath M
- Donaubauer T
- Dong X
- Dormidontova G
- Dorogova I
- Dos Santos A
- Dos Santos F
- Dos Santos P
- Doughty A
- Doughty L
- Dovgalevskiy Y
- Dovgolis S
- Dragutksy B
- Dreese M
- Drost I
- Drouin K
- Duchesne L
- Duckert A
- Duda N
- Dudarev M
- Dudhatra N
- Duff J
- Duhan S
- Dunhurst F
- Dussan Ma
- Dutka C
- Dwenger E
- Dzupina A
- Dékány Jn
- E Eleuteri
- E Englmann
- Earl J
- East C
- Eaton C
- Eaves W
- Ebeling K
- Ebrahim I
- Eccleston D
- Echeverria L
- Eder F
- Edgerton L
- Edillo C
- Edwards J
- Edwards T
- Eichinger G
- Einhorn D
- Eki Y
- El Hachem M
- El Hafi S
- Ellenbroek D
- Ellis M
- Emil B
- Endo T
- Engelen W
- Erhard M
- Erickson B
- Ervin W
- Eskridge L
- Espinosa V
- Everett Bm
- F Fedele
- F Fonseca
- F Fucci
- Facello A
- Facello M
- Faghih M
- Fail P
- Falcon D
- Fang C
- Fang Cy
- Farias E
- Fattal P
- Fawson A
- Feitosa G
- Felario Junior Ga
- Felix L
- Feng Y
- Feng Z
- Ferdinand K
- Ferkl R
- Fernandez Aa
- Ferrari V
- Ferrario M
- Ferraz R
- Ferreira Dos Santos T
- Ferreira-Jardim A
- Fien E
- Filardi Pp
- Filho P
- Fintel D
- Firek C
- Fischer Sm
- Fisher J
- Fitilev S
- Fitz-Patrick D
- Fitzpatrick L
- Flaksa I
- Flather M
- Flezar M
- Fliesser-Goerzer E
- Flores E
- Flores E
- Flores Gs
- Flores H
- Floro T
- Foerster A
- Folkeringa Rj
- Fonseca A
- Fontaine S
- Forgon T
- Forgosh L
- Forker A
- Forster T
- Foster M
- Foucauld J
- Fowler V
- Fox B
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- Francoeur L
- Frandsen B
- Frandsen B
- Frankenstein L
- Fratczak M
- Freitas E
- French J
- Frivold G
- Fruchter G
- Fu G
- Fucak E
- Fuchs R
- Fucili A
- Fukuike C
- Fullerton D
- Fulop P
- Fulop T
- Fulwani M
- Furch G
- Furuseth B
- G Gacioch
- G Gosselin
- Gabito A
- Gabor M
- Gabriel J
- Gabrielli D
- Gaeb-Strasas B
- Gamba C
- Ganau A
- Gapon L
- Garas S
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- Garcia Pinna J
- Garcia Rinaldi R
- Garcia F
- Garcia N
- Garcia-Fragoso V
- Garcia-Portela M
- Garner K
- Gazizianova V
- Gelb R
- Genest J
- Genova D
- George F
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- Goette A
- Goff R
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- Gohel P
- Goldberg N
- Gomez Sanchez J
- Gonsorcik J
- Gonzales D
- Gonzales V
- Gonzalez E
- Gordeev I
- Gorges R
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- Gotcheva N
- Goudev A
- Gould R
- Govindaraj D
- Goyal B
- Goyal S
- Grabeau R
- Grable M
- Graham J
- Graham Ja
- Graif J
- Gralow J
- Gravellone M
- Gravenhorst-Muenter U
- Green E
- Greener R
- Greenway F
- Grieshaber V
- Griffin S
- Grigaraviciene I
- Grigorova V
- Gros C
- Grosse A
- Grover A
- Grundtvig M
- Gudipati Rvc
- Guerrero A
- Guillinta P
- Gundala Ak
- Gupta A
- Gupta A
- Gupta M
- Gupta V
- Gutmann J
- Guzman I
- Guzman P
- Gwyn M
- Gyorgyova E
- H Haldane
- H Hansen
- H Haught
- H Hill
- Haase F
- Haege R
- Haenel T
- Hage F
- Hageman T
- Hagemann D
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- Hagiwara Y
- Haidar A
- Haider K
- Hakas J
- Haldis T
- Hall C
- Hall L
- Hall S
- Halliwell Tc
- Halpern S
- Hamer Bjb
- Hamud-Socoro A
- Han B
- Han S
- Hanak P
- Hanefeld M
- Hangyal T
- Hansson A
- Hanustiakova A
- Hao Y
- Hardas S
- Hardee L
- Harrell W
- Harrington A
- Harris B
- Hartleib M
- Hartwell J
- Hasan F
- Hasbani E
- Hasegawa K
- Hattler B
- Haughton G
- Haynes E
- Haywood A
- He Y
- He Z
- Heaney L
- Hecht J
- Heeren G
- Hegedus V
- Heider J
- Heisters J
- Henley L
- Hennig D
- Henriksson A
- Hermans K
- Hernandez E
- Hernandez I
- Hernandez M
- Hernández N
- Herrman Jp
- Herzog W
- Hess E
- Hettwer Magedanz E
- Hickey L
- Hiden C
- Hielscher S
- Higuchi T
- Higuchi Y
- Hilkert R
- Hilton T
- Himpel-Boenninghoff A
- Hinderaker P
- Hioki M
- Hirayama A
- Hiroma J
- Ho Cj
- Hodnett P
- Hoffman M
- Hofsoey K
- Hogan C
- Hollanders G
- Holmes Z
- Holoubek D
- Holscher A
- Hominal M
- Homza M
- Hong T
- Hong T
- Hoogslag Pam
- Horackova K
- Horak A
- Hornig M
- Horvat P
- Hosokawa S
- Hotchkiss D
- Houra M
- Hristova K
- Hsieh Ic
- Huang A
- Huang P
- Huang Ph
- Humbert J
- Hurtig U
- Hutchens E
- Huynh T
- Hwang Jj
- Hwang Jj
- Hyun K
- Härstedt N
- Høivik Ho
- I Ilic
- I Ivanov
- Iachini K
- Iannopollo G
- Ibarra J
- Ibarra M
- Ibañez J
- Iby M
- Ichisawa M
- Igbokidi O
- Iijima T
- Ilahi T
- Ilic S
- Ilsley M
- Imbrognio M
- Imre Bs
- Inada T
- Inagaki M
- Indolfi C
- Infusino F
- Invitti C
- Ipp E
- Isaza D
- Istratoaie O
- Istvan Kp
- Iteld B
- Ito K
- Ivan P
- Iveta H
- Izmozherova N
- J Jiang
- J Johnson
- J Johnston
- J Jose
- Jacques G
- Jafri A
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- Jagtap P
- Jaguszewska G
- Jain A
- Jansen M
- Jardula M
- Jayasinghe R
- Jefferson D
- Jenkins R
- Jensen Ed
- Jeric M
- Jerzewski A
- Jeserich M
- Jia Z
- Jiang T
- Jiang X
- Jimenez D
- Jirvankar P
- Johansen Bb
- Johansen E
- Johansson K
- Johnson E
- Jones S
- Jonsson Je
- Joosten C
- Joshi U
- Julien Ve
- Julião K
- Jure D
- Jure H
- Jutrisa N
- K Kaigawa
- K Katahira
- K Kiroglu
- K Kordic
- K Kostov
- Kabakchieva Vm
- Kaczmarek N
- Kafarakis P
- Kaiserova L
- Kajihara S
- Kala P
- Kaldara E
- Kalina A
- Kalkman C
- Kam J
- Kamensky G
- Kamiya H
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- Kan G
- Kaneno Y
- Kanitz S
- Kapp I
- Kara Yd
- Karakai H
- Karel I
- Karpuram M
- Karsai Xz
- Kastelein Jjp
- Kataoka M
- Katona A
- Katova T
- Kaur H
- Kawahara M
- Kawai M
- Kawasaki T
- Kawka-Urbanek T
- Kazanskay E
- Ke Y
- Keba E
- Keenan S
- Kelehan S
- Kellnerova I
- Kelly R
- Kelt T
- Kendall T
- Kereiakes D
- Khan A
- Khan M
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- Khan S
- Khariouzov A
- Khirmanov V
- Khromtsova O
- Kick J
- Kiefer R
- Kietselaer B
- Kim B
- Kim Ks
- Kim M
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- King A
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- Kirkland S
- Kiss Rg
- Kissel S
- Kitchens D
- Klamm M
- Klein C
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- Klemsdal To
- Kleve R
- Klugherz B
- Knight J
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- Koba M
- Kobalava Z
- Kodem Dr
- Koeitti P
- Koenig W
- Kojima E
- Kok M
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- Koleckar P
- Kolikova V
- Kolleroy C
- Kolokathis F
- Komati S
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- Kopaczewski J
- Kopczyńska M
- Korban E
- Koren M
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- Kose V
- Kosmacheva E
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- Kotek L
- Kouz Sm
- Kovacic D
- Kovacs A
- Kozak M
- Kozlova S
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- Kreckova M
- Kreutter F
- Krupciakova B
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- Kulibaba E
- Kulkarni L
- Kullal P
- Kultursay H
- Kumar Ks
- Kumbla M
- Kuntzsch A
- Kuo Jy
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- Kuruma T
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- Kuzin A
- Kyo E
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- L Lim
- L Link
- L Liu
- Laane E
- Labovitz R
- Lachance P
- Lai Wt
- Lail J
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- Liberato Nl
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- M Malek
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- M Mandati
- M Mandviwala
- M Marsters
- M Mays
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- M Mikus
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- Zielinski M
- Zieve F
- Zineldine A.
- Zirlik A
- Zucchetti C
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
- A Abbott
- A Abou-Raya
- A Aljandali
- A Ambesi-Impiombato
- A Aydin
- A Balcerczyk
- A Besarab
- A Brzezinski
- A Campbell
- A Carrillo-Vico
- A Cavalli
- A Chattopadhyay
- A Chattopadhyay
- A Cherubini
- A Dey
- A Doms
- A Donovan
- A Donovan
- A Dávalos
- A Gaeta
- A Garny
- A Gnjec
- A Gomes
- A Gopalakrishnan
- A Hald
- A Henney
- A Hirayama
- A Hoffmann
- A Huber
- A Hugman
- A Iannetti
- A Ide-Ektessabi
- A Jacobs
- A Jeyabalan
- A Kahvejian
- A Karrar
- A Kasztler
- A Kibel
- A Kocyigit
- A Kotha
- A Kumral
- A Lass
- A Lecube
- A Lewén
- A Lotery
- A Maggio
- A Malek
- A Malik
- A Mantovani
- A Matsuzawa
- A Mitra
- A Monge
- A Murakami
- A Murakami
- A Murakami
- A Murakami
- A Mutti
- A Nijnik
- A Nunomura
- A Nunomura
- A Patt
- A Persson
- A Pietrangelo
- A Piga
- A Pirat
- A Post
- A Pradhan
- A Protti
- A Rattner
- A Ravati
- A Rehman
- A Reynolds
- A Richmond
- A Roetto
- A Roetto
- A Rostom
- A Rumbold
- A Russo
- A Rötig
- A Saltelli
- A Saltelli
- A Sandek
- A Sassano
- A Scalbert
- A Scalbert
- A Scalbert
- A Sica
- A Smahi
- A Sola
- A Stintzi
- A Szewczyk
- A Taguchi
- A Tedgui
- A Terman
- A Terman
- A Terman
- A Undas
- A Virdis
- A Wagner
- A Wagner
- A Wagner
- A Wagner
- A Wojas-Pelc
- A Wong
- A Xu
- A Yoritaka
- A Yoshimura
- A-L Barabási
- AA Andreadis
- AA Borisy
- AA Farooqui
- AA Qutub
- AA Qutub
- AA Vlessis
- AB Nathens
- AB Parsons
- AB Parsons
- AB Thompson
- AB Thomson
- AC Bayne
- AC Bharti
- AC Cave
- AC Mello Filho
- AD d'Hardemare
- AD de Silva
- Ad hoc committee on systemic lupus erythematosus response criteria for fatigue
- ADL van der
- AE Aust
- AE Baue
- AE Finefrock
- AE Heazell
- AE Heazell
- AE Kartikasari
- AEC Ihekwaba
- AEC Ihekwaba
- AF Tramontano
- AH Berg
- AH Koeppen
- AH Koeppen
- AH Tong
- AI Bush
- AI Bush
- AI Bush
- AI Bush
- AI Faden
- AJ Ghio
- AJ Ghio
- AJ Ghio
- AJ Hulbert
- AJ Kowaltowski
- AJ Lusis
- AJ Matthews
- AJ Reyes
- AJ van Oostrom
- AJ Watson
- AJ White
- AJ Williams
- AK Junk
- AL Beal
- AL Hemdahl
- AL Hopkins
- AL Hopkins
- AL Lagan
- AL Mark
- AL Sirén
- AL Sirén
- AL Sirén
- AL Takeda
- AM Abeles
- AM Borzychowski
- AM Choi
- AM Dolga
- AM Elneihoum
- AM Elneihoum
- AM Feist
- AM Harvey
- AM Jenkinson
- AM Lin
- AM Samuni
- AM Snyder
- AN Crowson
- AN Tabah
- AP Bolger
- AP Breen
- AP Liappis
- AR Kallianpur
- AR Kallianpur
- AR Martin
- AR Ness
- AR Rechner
- AR Rumbold
- AS Baldwin Jr
- AS Binbrek
- AS Kaprelyants
- AS Wierzbicki
- AT McKie
- AV Lebedev
- AV Perkins
- AV Rao
- AW Maresso
- AY Andreyev
- AY Sun
- B Chakravarti
- B Chance
- B Cronin
- B de Valk
- B De Vries
- B Desoize
- B Drayer
- B Faller
- B Goodell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Halliwell
- B Huppertz
- B Jayawardhana
- B Kwak
- B Lachili
- B Lipinski
- B Mackenzie
- B Marshall
- B Mignotte
- B Oldenburg
- B Poeggeler
- B Pradines
- B Pradines
- B Regland
- B Russell
- B Schiessl
- B Shipley
- B Skibska
- B Sturm
- B Thorand
- B Wang
- B Wolff
- B Wolozin
- B Wolozin
- B Xu
- B Zhang
- B Zhou
- BA Maddux
- BA Molitoris
- BB Aggarwal
- BB Aggarwal
- BB Aggarwal
- BB Aggarwal
- BB Sizoo
- BB Song
- BB Song
- BC Daniels
- BC Jones
- BD LaMarca
- BH Havsteen
- BI Giasson
- BI Hoffman
- BJ Marshall
- BK Kennedy
- BK Rinehart
- BK Wagner
- BL Halvorsen
- BL Zhao
- BM Babior
- BN Ames
- BP Leung
- BP Oberg
- BP Yu
- BR Kwak
- BR Otto
- BS Chen
- BS van Asbeck
- BT Mossman
- BV Naidu
- BY Tung
- BØ Palsson
- C Arnaud
- C Beaumont
- C Behl
- C Biondi
- C Bolin
- C Bozzini
- C Breymann
- C Brooksbank
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- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
Erratum: Measurement of angular and momentum distributions of charged particles within and around jets in Pb + Pb and pp collisions at √sNN = 5.02 TeV with the ATLAS detector [Phys. Rev. C 100 , 064901 (2019)]
- Author
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- Berry T
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- Bertella C
- Bertram Ia
- Bessidskaia Bylund O
- Besson N
- Bethani A
- Bethke S
- Betti A
- Bevan Aj
- Beyer J
- Bhattacharya Ds
- Bhattarai P
- Bi R
- Bianchi Rm
- Biebel O
- Biedermann D
- Bielski R
- Bierwagen K
- Biesuz Nv
- Biglietti M
- Billoud Trv
- Bindi M
- Bingul A
- Bini C
- Biondi S
- Birman M
- Bisanz T
- Biswal Jp
- Biswas D
- Bitadze A
- Bittrich C
- Bjorke K
- Black Km
- Blazek T
- Bloch I
- Blocker C
- Blue A
- Blumenschein U
- Bobbink Gj
- Bobrovnikov Vs
- Bocchetta Ss
- Bocci A
- Boerner D
- Bogavac D
- Bogdanchikov Ag
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Boldyrev As
- Bolz Ae
- Bomben M
- Bona M
- Bonilla Js
- Boonekamp M
- Booth Cd
- Borecka-Bielska Hm
- Borisov A
- Borissov G
- Bortfeldt J
- Bortoletto D
- Boscherini D
- Bosman M
- Bossio Sola Jd
- Bouaouda K
- Boudreau J
- Bouhova-Thacker Ev
- Boumediene D
- Boutle Sk
- Boveia A
- Boyd J
- Boye D
- Boyko Ir
- Bozson Aj
- Bracinik J
- Brahimi N
- Brandt G
- Brandt O
- Braren F
- Brau B
- Brau Je
- Breaden Madden Wd
- Brendlinger K
- Brenner L
- Brenner R
- Bressler S
- Brickwedde B
- Briglin Dl
- Britton D
- Britzger D
- Brock I
- Brock R
- Brooijmans G
- Brooks Wk
- Brost E
- Broughton Jh
- Bruckman De Renstrom Pa
- Bruncko D
- Bruni A
- Bruni G
- Bruni Ls
- Bruno S
- Brunt Bh
- Bruschi M
- Bruscino N
- Bryant P
- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley Ag
- Budagov Ia
- Bugge Mk
- Buhrer F
- Bulekov O
- Burch Tj
- Burdin S
- Burgard Cd
- Burger Am
- Burghgrave B
- Burr Jtp
- Burton Cd
- Burzynski Jc
- Buscher V
- Buschmann E
- Bussey Pj
- Butler Jm
- Buttar Cm
- Butterworth Jm
- Butti P
- Buttinger W
- Buxo Vazquez Cj
- Buzatu A
- Buzykaev Ar
- Cabras G
- Cabrera Urban S
- Caforio D
- Cai H
- Cairo Vmm
- Cakir O
- Calace N
- Calafiura P
- Calandri A
- Calderini G
- Calfayan P
- Callea G
- Caloba Lp
- Calvente Lopez S
- Calvet D
- Calvet S
- Calvet Tp
- Calvetti M
- Camacho Toro R
- Camarda S
- Camarero Munoz D
- Camarri P
- Cameron D
- Caminal Armadans R
- Camincher C
- Campana S
- Campanelli M
- Camplani A
- Campoverde A
- Canale V
- Canesse A
- Cano Bret M
- Cantero J
- Cao T
- Cao Y
- Capeans Garrido Mdm
- Capua M
- Cardarelli R
- Cardillo F
- Carducci G
- Carli I
- Carli T
- Carlino G
- Carlson Bt
- Carminati L
- Carney Rmd
- Caron S
- Carquin E
- Carra S
- Carter Jws
- Casado Mp
- Casha Af
- Casper Dw
- Castelijn R
- Castillo Gimenez V
- Castillo Fl
- Castro Nf
- Catinaccio A
- Catmore Jr
- Cattai A
- Caudron J
- Cavaliere V
- Cavallaro E
- Cavalli-Sforza M
- Cavasinni V
- Celebi E
- Ceradini F
- Cerda Alberich L
- Cerny K
- Cerqueira As
- Cerri A
- Cerrito L
- Cerutti F
- Cervelli A
- Cetin Sa
- Chadi Z
- Chakraborty D
- Chan Sk
- Chan Ws
- Chan Wy
- Chapman Jd
- Chargeishvili B
- Charlton Dg
- Charman Tp
- Chau Cc
- Che S
- Chekanov S
- Chekulaev Sv
- Chelkov Ga
- Chelstowska Ma
- Chen B
- Chen C
- Chen Ch
- Chen H
- Chen J
- Chen J
- Chen S
- Chen Sj
- Chen X
- Chen Y
- Chen Y-
- Cheng Hc
- Cheng Hj
- Cheplakov A
- Cheremushkina E
- Cherkaoui El Moursli R
- Cheu E
- Cheung K
- Chevalerias Tja
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiodini G
- Chisholm As
- Chitan A
- Chiu I
- Chiu Yh
- Chizhov Mv
- Choi K
- Chomont Ar
- Chouridou S
- Chow Ys
- Chu Mc
- Chu X
- Chudoba J
- Chuinard Aj
- Chwastowski Jj
- Chytka L
- Cieri D
- Ciesla Km
- Cinca D
- Cindro V
- Cioara Ia
- Ciocio A
- Cirotto F
- Citron Zh
- Citterio M
- Ciubotaru Da
- Ciungu Bm
- Clark A
- Clark Mr
- Clark Pj
- Clement C
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Cohen H
- Coimbra Aec
- Colasurdo L
- Cole B
- Colijn Ap
- Collot J
- Conde Muino P
- Coniavitis E
- Connell Sh
- Connelly Ia
- Constantinescu S
- Conventi F
- Cooper-Sarkar Am
- Cormier F
- Cormier Kjr
- Corpe Ld
- Corradi M
- Corrigan Ee
- Corriveau F
- Cortes-Gonzalez A
- Costa Mj
- Costanza F
- Costanzo D
- Cowan G
- Cowley Jw
- Crane J
- Cranmer K
- Crawley Sj
- Creager Ra
- Crepe-Renaudin S
- Crescioli F
- Cristinziani M
- Croft V
- Crosetti G
- Cueto A
- Cuhadar Donszelmann T
- Cukierman Ar
- Cunningham Wr
- Czekierda S
- Czodrowski P
- D'Amen G
- D'Amico V
- D'Auria S
- D'Eramo L
- D'Onofrio A
- D'Onofrio M
- Da Cunha Sargedas De Sousa Mj
- Da Fonseca Pinto Jv
- Da Via C
- Dabrowski W
- Dado T
- Dahbi S
- Dai T
- Dallapiccola C
- Dam M
- Damp J
- Dandoy Jr
- Daneri Mf
- Dang Np
- Dann Ns
- Danninger M
- Dao V
- Darbo G
- Dartsi O
- Dattagupta A
- Daubney T
- Davey W
- David C
- Davidek T
- Davis Dr
- Dawson I
- De Asmundis R
- De Beurs M
- De Castro S
- De Cecco S
- De Groot N
- De Jong P
- De La Torre H
- De Maria A
- De Pedis D
- De Salvo A
- De Sanctis U
- De Santis M
- De Santo A
- De Vasconcelos Corga K
- De Vivie De Regie Jb
- De K
- Debenedetti C
- Dedovich Dv
- Deiana Am
- Del Gaudio M
- Del Peso J
- Delabat Diaz Y
- Delgove D
- Deliot F
- Delitzsch Cm
- Dell'Acqua A
- Dell'Asta L
- Della Pietra M
- Della Volpe D
- Delmastro M
- Delporte C
- Delsart Pa
- Demarco Da
- Demers S
- Demichev M
- Demontigny G
- Denisov Sp
- Denysiuk D
- Derendarz D
- Derkaoui Je
- Derue F
- Dervan P
- Desch K
- Deterre C
- Dette K
- Deutsch C
- Devesa Mr
- Deviveiros Po
- Dewhurst A
- Di Bello Fa
- Di Ciaccio A
- Di Ciaccio L
- Di Clemente Wk
- Di Donato C
- Di Girolamo A
- Di Gregorio G
- Di Micco B
- Di Nardo R
- Di Petrillo Kf
- Di Sipio R
- Di Valentino D
- Diaconu C
- Dias Do Vale T
- Dias Fa
- Diaz Ma
- Dickinson J
- Diehl Eb
- Dietrich J
- Diez Cornell S
- Dimitrievska A
- Ding W
- Dingfelder J
- Dittus F
- Djama F
- Djobava T
- Djuvsland Ji
- Do Vale Mab
- Dobre M
- Dodsworth D
- Doglioni C
- Dolejsi J
- Dolezal Z
- Donadelli M
- Dong B
- Donini J
- Dopke J
- Doria A
- Dova Mt
- Doyle At
- Drechsler E
- Dreyer E
- Dreyer T
- Drobac As
- Du D
- Duan Y
- Dubinin F
- Dubovsky M
- Dubreuil A
- Duchovni E
- Duckeck G
- Ducourthial A
- Ducu Oa
- Duda D
- Dudarev A
- Dudder Ac
- Duffield Em
- Duflot L
- Duhrssen M
- Dulsen C
- Dumancic M
- Dumitriu Ae
- Duncan Ak
- Dunford M
- Duperrin A
- Duran Yildiz H
- Duren M
- Durglishvili A
- Duschinger D
- Dutta B
- Duvnjak D
- Dyckes Gi
- Dyndal M
- Dysch S
- Dziedzic Bs
- Ecker Km
- Edgar Rc
- Eggleston Mg
- Eifert T
- Eigen G
- Einsweiler K
- Ekelof T
- El Jarrari H
- El Kacimi M
- El Kosseifi R
- Ellajosyula V
- Ellert M
- Ellinghaus F
- Elliot Aa
- Ellis N
- Elmsheuser J
- Elsing M
- Emeliyanov D
- Emerman A
- Enari Y
- Epland Mb
- Erdmann J
- Ereditato A
- Errenst M
- Escalier M
- Escobar C
- Estrada Pastor O
- Etzion E
- Evans H
- Ezhilov A
- Fabbri F
- Fabbri L
- Fabiani V
- Facini G
- Faisca Rodrigues Pereira Rm
- Fakhrutdinov Rm
- Falciano S
- Falke Pj
- Falke S
- Faltova J
- Fang Y
- Fang Y
- Fanourakis G
- Fanti M
- Faraj M
- Farbin A
- Farilla A
- Farina Em
- Farooque T
- Farrell S
- Farrington Sm
- Farthouat P
- Fassi F
- Fassnacht P
- Fassouliotis D
- Faucci Giannelli M
- Fawcett Wj
- Fayard L
- Fedin Ol
- Fedorko W
- Feickert M
- Feligioni L
- Fell A
- Feng C
- Feng Ej
- Feng M
- Fenton Mj
- Fenyuk Ab
- Ferrando J
- Ferrante A
- Ferrari A
- Ferrari P
- Ferrari R
- Ferreira De Lima De
- Ferrer A
- Ferrere D
- Ferretti C
- Fiedler F
- Filipcic A
- Filthaut F
- Finelli Kd
- Fiolhais Mcn
- Fiorini L
- Fischer F
- Fisher Wc
- Fleck I
- Fleischmann P
- Fletcher Rrm
- Flick T
- Flierl Bm
- Flores Castillo Lr
- Flores L
- Follega Fm
- Fomin N
- Foo Jh
- Forcolin Gt
- Formica A
- Forster Fa
- Forti Ac
- Foster Ag
- Foti Mg
- Fournier D
- Fox H
- Francavilla P
- Francescato S
- Franchini M
- Franchino S
- Francis D
- Franconi L
- Franklin M
- Fray An
- Freeman Pm
- Freund B
- Freund Ws
- Freundlich Em
- Frizzell Dc
- Froidevaux D
- Frost Ja
- Fukunaga C
- Fullana Torregrosa E
- Fumagalli E
- Fusayasu T
- Fuster J
- Gabrielli A
- Gabrielli A
- Gach Gp
- Gadatsch S
- Gadow P
- Gagliardi G
- Gagnon Lg
- Galea C
- Galhardo B
- Gallardo Ge
- Gallas Ej
- Gallop Bj
- Galster G
- Gamboa Goni R
- Gan Kk
- Ganguly S
- Gao J
- Gao Y
- Gao Ys
- Garcia Navarro Je
- Garcia Pascual Ja
- Garcia C
- Garcia-Argos C
- Garcia-Sciveres M
- Gardner Rw
- Garelli N
- Gargiulo S
- Garonne V
- Gaudiello A
- Gaudio G
- Gavrilenko Il
- Gavrilyuk A
- Gay C
- Gaycken G
- Gazis En
- Geanta Aa
- Gee Cm
- Gee Cnp
- Geisen J
- Geisen M
- Geisler Mp
- Gemme C
- Genest Mh
- Geng C
- Gentile S
- George S
- Geralis T
- Gerlach Lo
- Gessinger-Befurt P
- Gessner G
- Ghasemi Bostanabad M
- Ghasemi S
- Ghosh A
- Ghosh A
- Giacobbe B
- Giagu S
- Giangiacomi N
- Giannetti P
- Giannini A
- Giannini G
- Gibson Sm
- Gignac M
- Gillberg D
- Gilles G
- Gingrich Dm
- Giordani Mp
- Giorgi Fm
- Giraud Pf
- Giugliarelli G
- Giugni D
- Giuli F
- Gkaitatzis S
- Gkialas I
- Gkougkousis El
- Gkountoumis P
- Gladilin Lk
- Glasman C
- Glatzer J
- Glaysher Pcf
- Glazov A
- Gledhill Gr
- Goblirsch-Kolb M
- Godin D
- Goldfarb S
- Golling T
- Golubkov D
- Gomes A
- Goncalo R
- Goncalves Gama R
- Gonella G
- Gonella L
- Gongadze A
- Gonnella F
- Gonski Jl
- Gonzalez De La Hoz S
- Gonzalez-Sevilla S
- Gonzalvo Rodriguez Gr
- Goossens L
- Gorbounov Pa
- Gordon Ha
- Gorini B
- Gorini E
- Gorisek A
- Goshaw At
- Gostkin Mi
- Gottardo Ca
- Gouighri M
- Goujdami D
- Goussiou Ag
- Govender N
- Goy C
- Gozani E
- Grabowska-Bold I
- Graham Ec
- Gramling J
- Gramstad E
- Grancagnolo S
- Grandi M
- Gratchev V
- Gravila Pm
- Gravili Fg
- Gray C
- Gray Hm
- Grefe C
- Gregersen K
- Gregor Im
- Grenier P
- Grevtsov K
- Grieco C
- Grieser Na
- Griffiths J
- Grillo Aa
- Grimm K
- Grinstein S
- Grivaz J-
- Groh S
- Gross E
- Grosse-Knetter J
- Grout Zj
- Grud C
- Grummer A
- Guan L
- Guan W
- Guenther J
- Guerguichon A
- Guerrero Rojas Jgr
- Guescini F
- Guest D
- Gugel R
- Guillemin T
- Guindon S
- Gul U
- Guo J
- Guo W
- Guo Y
- Guo Z
- Gupta R
- Gurbuz S
- Gustavino G
- Guth M
- Gutierrez P
- Gutschow C
- Guyot C
- Gwenlan C
- Gwilliam Cb
- Haas A
- Haber C
- Hadavand Hk
- Haddad N
- Hadef A
- Hagebock S
- Haleem M
- Haley J
- Halladjian G
- Hallewell Gd
- Hamacher K
- Hamal P
- Hamano K
- Hamdaoui H
- Hamity Gn
- Han K
- Han L
- Han S
- Han Yf
- Hanagaki K
- Hance M
- Handl Dm
- Haney B
- Hankache R
- Hansen E
- Hansen Jb
- Hansen Jd
- Hansen Mc
- Hansen Ph
- Hanson Ec
- Hara K
- Harenberg T
- Harkusha S
- Harrison Pf
- Hartmann Nm
- Hasegawa Y
- Hasib A
- Hassani S
- Haug S
- Hauser R
- Havener Lb
- Havranek M
- Hawkes Cm
- Hawkings Rj
- Hayden D
- Hayes C
- Hayes Rl
- Hays Cp
- Hays Jm
- Hayward Hs
- Haywood Sj
- He F
- Heath Mp
- Hedberg V
- Heelan L
- Heer S
- Heidegger Kk
- Heidorn Wd
- Heilman J
- Heim S
- Heim T
- Heinemann B
- Heinrich Jj
- Heinrich L
- Heinz C
- Hejbal J
- Helary L
- Held A
- Hellesund S
- Helling Cm
- Hellman S
- Helsens C
- Henderson Rcw
- Heng Y
- Henkelmann S
- Henriques Correia Am
- Herbert Gh
- Herde H
- Herget V
- Hernandez Jimenez Y
- Herr H
- Herrmann Mg
- Herrmann T
- Herten G
- Hertenberger R
- Hervas L
- Herwig Tc
- Hesketh Gg
- Hessey Np
- Higashida A
- Higashino S
- Higon-Rodriguez E
- Hildebrand K
- Hill E
- Hill Jc
- Hill Kk
- Hiller Kh
- Hillier Sj
- Hils M
- Hinchliffe I
- Hinterkeuser F
- Hirose M
- Hirose S
- Hirschbuehl D
- Hiti B
- Hladik O
- Hlaluku Dr
- Hoad X
- Hobbs J
- Hod N
- Hodgkinson Mc
- Hoecker A
- Hoenig F
- Hohn D
- Hohov D
- Holmes Tr
- Holzbock M
- Hommels Lbah
- Honda S
- Hong Tm
- Honig Jc
- Honle A
- Hooberman Bh
- Hopkins Wh
- Horii Y
- Horn P
- Horyn La
- Hou S
- Hoummada A
- Howarth J
- Hoya J
- Hrabovsky M
- Hrdinka J
- Hristova I
- Hrivnac J
- Hryn'Ova T
- Hrynevich A
- Hsu Pj
- Hsu S-
- Hu Q
- Hu S
- Hu Yf
- Huang Dp
- Huang Y
- Huang Y
- Hubacek Z
- Hubaut F
- Huebner M
- Huegging F
- Huffman Tb
- Huhtinen M
- Hunter Rfh
- Huo P
- Hupe Am
- Huseynov N
- Huston J
- Huth J
- Hyneman R
- Hyrych S
- Iacobucci G
- Iakovidis G
- Ibragimov I
- Iconomidou-Fayard L
- Idrissi Z
- Iengo P
- Ignazzi R
- Igonkina O
- Iguchi R
- Iizawa T
- Ikegami Y
- Ikeno M
- Iliadis D
- Ilic N
- Iltzsche F
- Introzzi G
- Iodice M
- Iordanidou K
- Ippolito V
- Isacson Mf
- Ishino M
- Islam W
- Issever C
- Istin S
- Ito F
- Iturbe Ponce Jm
- Iuppa R
- Ivina A
- Iwasaki H
- Izen Jm
- Izzo V
- Jacka P
- Jackson P
- Jacobs Rm
- Jaeger Bp
- Jain V
- Jakel G
- Jakobi Kb
- Jakobs K
- Jakobsen S
- Jakoubek T
- Jamieson J
- Janas Kw
- Jansky R
- Janssen J
- Janus M
- Janus Pa
- Jarlskog G
- Javadov N
- Javurek T
- Javurkova M
- Jeanneau F
- Jeanty L
- Jejelava J
- Jelinskas A
- Jenni P
- Jeong J
- Jeong N
- Jezequel S
- Ji H
- Jia J
- Jiang H
- Jiang Y
- Jiang Z
- Jiggins S
- Jimenez Morales Fa
- Jimenez Pena J
- Jin S
- Jinaru A
- Jinnouchi O
- Jivan H
- Johansson P
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- Jones Rwl
- Jones S
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- Jones Tj
- Jongmanns J
- Jorge Pm
- Jovicevic J
- Ju X
- Junggeburth Jj
- Juste Rozas A
- Kaczmarska A
- Kado M
- Kagan H
- Kagan M
- Kahra C
- Kaji T
- Kajomovitz E
- Kalderon Cw
- Kaluza A
- Kamenshchikov A
- Kaneda M
- Kanjir L
- Kano Y
- Kantserov Va
- Kanzaki J
- Kaplan Ls
- Kar D
- Karava K
- Kareem Mj
- Karpov Sn
- Karpova Zm
- Kartvelishvili V
- Karyukhin An
- Kashif L
- Kass Rd
- Kastanas A
- Kato C
- Katzy J
- Kawade K
- Kawagoe K
- Kawaguchi T
- Kawamoto T
- Kawamura G
- Kay Ef
- Kazanin Vf
- Keeler R
- Kehoe R
- Keller Js
- Kellermann E
- Kelsey D
- Kempster Jj
- Kendrick J
- Kepka O
- Kersevan Bp
- Kersten S
- Ketabchi Haghighat S
- Khader M
- Khalil-Zada F
- Khandoga M
- Khanov A
- Kharlamov Ag
- Kharlamova T
- Khoda Ee
- Khodinov A
- Khoo Tj
- Khramov E
- Khubua J
- Kido S
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- Kilby Cr
- Kim Yk
- Kimura N
- Kind Om
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- Kirchmeier D
- Kirk J
- Kiryunin Ae
- Kishimoto T
- Kisliuk Dp
- Kitali V
- Kivernyk O
- Klapdor-Kleingrothaus T
- Klassen M
- Klein M
- Klein Mh
- Klein U
- Kleinknecht K
- Klimek P
- Klimentov A
- Klingl T
- Klioutchnikova T
- Klitzner Ff
- Kluit P
- Kluth S
- Kneringer E
- Knoops Ebfg
- Knue A
- Kobayashi D
- Kobayashi T
- Kobel M
- Kocian M
- Kodys P
- Koenig Pt
- Koffas T
- Kohler Nm
- Koi T
- Kolb M
- Koletsou I
- Komarek T
- Kondo T
- Kondrashova N
- Koneke K
- Konig Ac
- Kono T
- Konoplich R
- Konstantinides V
- Konstantinidis N
- Konya B
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- Koperny S
- Korcyl K
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- Koren G
- Korn A
- Korolkov I
- Korolkova Ev
- Korotkova N
- Kortner O
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- Kosek T
- Kostyukhin Vv
- Kotsokechagia A
- Kotwal A
- Koulouris A
- Kourkoumeli-Charalampidi A
- Kourkoumelis C
- Kourlitis E
- Kouskoura V
- Kowalewska Ab
- Kowalewski R
- Kozakai C
- Kozanecki W
- Kozhin As
- Kramarenko Va
- Kramberger G
- Krasnopevtsev D
- Krasny Mw
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- Krauss D
- Kremer Ja
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- Kubota T
- Kuchinskaia O
- Kuday S
- Kuechler Jt
- Kuehn S
- Kugel A
- Kuhl T
- Kukhtin V
- Kukla R
- Kulchitsky Y
- Kuleshov S
- Kulinich Yp
- Kuna M
- Kunigo T
- Kupco A
- Kupfer T
- Kuprash O
- Kurashige H
- Kurchaninov Ll
- Kurochkin Ya
- Kurova A
- Kurth Mg
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- La Rotonda L
- La Ruffa F
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- Liberti B
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- Turchikhin S
- Turgeman D
- Turk Cakir I
- Turner Rj
- Turra Rt
- Tuts Pm
- Tzamarias S
- Tzovara E
- Ucchielli G
- Uchida K
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- Ughetto M
- Ukegawa F
- Unal G
- Undrus A
- Unel G
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- Unno Y
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- Vermeulen Jc
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- Vorobel V
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- Wieseotte N
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- Wong Vws
- Woods Nl
- Worm Sd
- Wosiek Bk
- Wozniak Kw
- Wraight K
- Wu Sl
- Wu X
- Wu Y
- Wyatt Tr
- Wynne Bm
- Xella S
- Xi Z
- Xia L
- Xiao X
- Xiotidis I
- Xu D
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- Yabsley B
- Yacoob S
- Yajima K
- Yallup Dp
- Yamaguchi D
- Yamaguchi Y
- Yamamoto A
- Yamatani M
- Yamazaki T
- Yamazaki Y
- Yan Z
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- Yao W-
- Yap Yc
- Yasu Y
- Yatsenko E
- Ye J
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- Yexley Mr
- Yigitbasi E
- Yorita K
- Yoshihara K
- Young C
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- Yu J
- Yuan R
- Yue X
- Yuen Spy
- Zaazoua M
- Zabinski B
- Zacharis G
- Zaffaroni E
- Zahreddine J
- Zaitsev Am
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zanzi D
- Zaripovas Dr
- Zeissner Sv
- Zeitnitz C
- Zemaityte G
- Zeng Jc
- Zenin O
- Zenis T
- Zerwas D
- Zgubic M
- Zhang B
- Zhang Df
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang L
- Zhang M
- Zhang R
- Zhang X
- Zhang Y
- Zhang Z
- Zhang Z
- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
- Zhou Ms
- Zhou N
- Zhou Y
- Zhu C
- Zhu Cg
- Zhu H
- Zhu Hl
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine Ni
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas Tg
- Zou R
- Zwalinski L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2020
- Field of study
Measurement of the tt¯tt¯ production cross section in pp collisions at √s=13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abed Abud A
- Abeling K
- Abhayasinghe DK
- Abidi SH
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Achkar B
- Adam Bourdarios C
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adiguzel A
- Adorni S
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- Alberghi GL
- Albert J
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- Andrei V
- Angelidakis S
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antipov E
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- Antrim DJA
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- Aparisi Pozo JA
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- Aranzabal N
- Araujo Ferraz V
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- de Jong P
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- Denisov SP
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- Zakharchuk N
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- Zeißner SV
- Zemaityte G
- Zeng JC
- Zenin O
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- Zerwas D
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- Zhemchugov A
- Zheng Z
- Zhong D
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- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Ziolkowski M
- Zoccoli A
- Zoch K
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 16/11/2021
- Field of study
A measurement of four-top-quark production using proton-proton collision data at a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider corresponding to an integrated luminosity of 139 fb−1 is presented. Events are selected if they contain a single lepton (electron or muon) or an opposite-sign lepton pair, in association with multiple jets. The events are categorised according to the number of jets and how likely these are to contain b-hadrons. A multivariate technique is then used to discriminate between signal and background events. The measured four-top-quark production cross section is found to be 26+17−15 fb, with a corresponding observed (expected) significance of 1.9 (1.0) standard deviations over the background-only hypothesis. The result is combined with the previous measurement performed by the ATLAS Collaboration in the multilepton final state. The combined four-top-quark production cross section is measured to be 24+7−6 fb, with a corresponding observed (expected) signal significance of 4.7 (2.6) standard deviations over the background-only predictions. It is consistent within 2.0 standard deviations with the Standard Model expectation of 12.0 ± 2.4 fb
Performance of the upgraded PreProcessor of the ATLAS Level-1 Calorimeter Trigger
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- Xu D
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- Yabsley B
- Yacoob S
- Yajima K
- Yallup DP
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- Yildiz H Duran
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- Yoshihara K
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- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
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- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen H Meyer
- Zwalinski L
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2020
- Field of study
The PreProcessor of the ATLAS Level-1 Calorimeter Trigger prepares the analogue trigger signals sent from the ATLAS calorimeters by digitising, synchronising, and calibrating them to reconstruct transverse energy deposits, which are then used in further processing to identify event features. During the first long shutdown of the LHC from 2013 to 2014, the central components of the PreProcessor, the Multichip Modules, were replaced by upgraded versions that feature modern ADC and FPGA technology to ensure optimal performance in the high pile-up environment of LHC Run 2. This paper describes the features of the newMultichip Modules along with the improvements to the signal processing achieved.ANPCyTYerPhI, ArmeniaAustralian Research CouncilBMWFW, AustriaAustrian Science Fund (FWF)Azerbaijan National Academy of Sciences (ANAS)SSTC, BelarusNational Council for Scientific and Technological Development (CNPq)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)Natural Sciences and Engineering Research Council of CanadaCanada Foundation for InnovationNational Natural Science Foundation of China (NSFC)Departamento Administrativo de Ciencia, Tecnología e Innovación ColcienciasMinistry of Education, Youth & Sports - Czech Republic
Czech Republic GovernmentCzech Republic GovernmentDNRF, DenmarkDanish Natural Science Research CouncilCentre National de la Recherche Scientifique (CNRS)CEA-DRF/IRFU, FranceFederal Ministry of Education & Research (BMBF)Max Planck SocietyGreek Ministry of Development-GSRTRGC and Hong Kong SAR, ChinaIsrael Science FoundationBenoziyo Center, IsraelIstituto Nazionale di Fisica Nucleare (INFN)Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT)
Japan Society for the Promotion of ScienceCNRST, MoroccoRCN, NorwayPortuguese Foundation for Science and TechnologyMNE/IFA, RomaniaMES of RussiaMESTD, SerbiaMSSR, SlovakiaSlovenian Research Agency - SloveniaMIZS, SloveniaSpanish GovernmentSRC, SwedenWallenberg Foundation, SwedenSNSF Geneva, SwitzerlandMinistry of Science and Technology, TaiwanMinistry of Energy & Natural Resources - TurkeyScience & Technology Facilities Council (STFC)United States Department of Energy (DOE)National Science Foundation (NSF)BCKDF, CanadaCANARIE, CanadaCRC, CanadaEuropean Research Council (ERC)European Union (EU)French National Research Agency (ANR)German Research Foundation (DFG)Alexander von Humboldt FoundationGreek NSRF, GreeceBSF-NSF, IsraelGerman-Israeli Foundation for Scientific Research and DevelopmentLa Caixa Banking Foundation, SpainCERCA Programme Generalitat de Catalunya, SpainPROMETEO, SpainGenT Programmes Generalitat Valenciana, SpainGoran Gustafssons Stiftelse, SwedenRoyal Society of LondonLeverhulme TrustNRC, CanadaCERNANID, ChileChinese Academy of SciencesMinistry of Science and Technology, ChinaSRNSFG, GeorgiaHGF, GermanyNetherlands Organization for Scientific Research (NWO)
Netherlands GovernmentMinistry of Science and Higher Education, PolandNCN, PolandNRCKI, Russia FederationJINRDST/NRF, South AfricaSERI, Geneva, SwitzerlandCantons of Bern and Geneva, SwitzerlandCompute Canada, CanadaHorizon 2020Marie Sklodowska-Curie ActionsEuropean Cooperation in Science and Technology (COST)EU-ESF, Greec
Measurements of W+W−+ ≥ 1 jet production cross-sections in pp collisions at s = 13 TeV with the ATLAS detector
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- Zhemchugov A
- Zheng Z
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- Zinonos Z
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/06/2021
- Field of study
Fiducial and differential cross-section measurements of W+W− production in
association with at least one hadronic jet are presented. These measurements are sensitive
to the properties of electroweak-boson self-interactions and provide a test of perturbative
quantum chromodynamics and the electroweak theory. The analysis is performed using
proton-proton collision data collected at p
s = 13TeV with the ATLAS experiment, corresponding
to an integrated luminosity of 139 fb−1. Events are selected with exactly one oppositely
charged electron-muon pair and at least one hadronic jet with a transverse momentum
of pT > 30 GeV and a pseudorapidity of |�| < 4.5. After subtracting the background
contributions and correcting for detector effects, the jet-inclusive W+W−+ � 1 jet fiducial
cross-section and W+W−+ jets differential cross-sections with respect to several kinematic
variables are measured. These measurements include leptonic quantities, such as the lepton
transverse momenta and the transverse mass of the W+W− system, as well as jet-related
observables such as the leading jet transverse momentum and the jet multiplicity. Limits on
anomalous triple-gauge-boson couplings are obtained in a phase space where interference
between the Standard Model amplitude and the anomalous amplitude is enhanced
Dijet Resonance Search with Weak Supervision Using root S=13 TeV pp Collisions in the ATLAS Detector
- Author
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- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou H
- Zhou M
- Zhou MS
- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine N
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- AMER PHYSICAL SOC
- Publication date
- 25/09/2020
- Field of study
This Letter describes a search for narrowly resonant new physics using a machine-learning anomaly
detection procedure that does not rely on signal simulations for developing the analysis selection. Weakly
supervised learning is used to train classifiers directly on data to enhance potential signals. The targeted
topology is dijet events and the features used for machine learning are the masses of the two jets. The
resulting analysis is essentially a three-dimensional search A → BC, for mA ∼ OðTeVÞ, mB; mC ∼
Oð100 GeVÞ and B, C are reconstructed as large-radius jets, without paying a penalty associated with
a large trials factor in the scan of the masses of the two jets. The full run 2 ffiffi
s p ¼ 13 TeV pp collision
dataset of 139 fb−1 recorded by the ATLAS detector at the Large Hadron Collider is used for the search.
There is no significant evidence of a localized excess in the dijet invariant mass spectrum between 1.8 and
8.2 TeV. Cross-section limits for narrow-width A, B, and C particles vary with mA, mB, and mC. For
example, when mA ¼ 3 TeV and mB ≳ 200 GeV, a production cross section between 1 and 5 fb is
excluded at 95% confidence level, depending on mC. For certain masses, these limits are up to 10 times
more sensitive than those obtained by the inclusive dijet search. These results are complementary to the
dedicated searches for the case that B and C are standard model boson
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