2,121 research outputs found
On quadratic stability of systems with structured uncertainty
This note considers the problem of stability robustness with respect to a class of nonlinear time-varying perturbations which are bounded in a component-wise rather than aggregated manner. A family of robustness bounds is parameterized in terms of a nonsingular symmetric matrix. It is shown that the problem of computing the largest robustness bound over the set of nonsingular symmetric matrices can be approximated by a smooth minimization problem over a compact set. A convergent algorithm for computing an optimal robustness bound is proposed in the form of a gradient flow.published_or_final_versio
An approximate approach to H 2 optimal model reduction
This paper deals with the problem of computing an H 2 optimal reduced-order model for a given stable multivariable linear system. By way of orthogonal projection, the problem is formulated as that of minimizing the H 2 model-reduction cost over the Stiefel manifold so that the stability constraint on reduced-order models is automatically satisfied and thus totally avoided in the new problem formulation. The closed form expression for the gradient of the cost over the manifold is derived, from which a gradient flow results as an ordinary differential equation (ODE). A number of nice properties about such a flow are established. Furthermore, two explicit iterative convergent algorithms are developed from the flow; one has a constant step-size and the other has a varying step-size and is much more efficient. Both of them inherit the properties that the iterates remain on the manifold starting from any orthogonal initial point and that the model reduction cost is decreasing to minima along the iterates. A procedure for closing the gap between the original and modified problem is proposed. In the symmetric case, the two problems are shown to be equivalent. Numerical examples are presented to illustrate the effectiveness of the proposed algorithms as well as convergence.published_or_final_versio
On the nonlinearly structured stability radius problem
This paper considers the problem of finding a perturbation matrix with the least spectral norm such that a matrix-valued function becomes singular, where the dependence of the function on the perturbation is allowed to be nonlinear. It is proved that such a problem can be approximated by a smooth unconstrained minimization problem with compact sublevel sets. A computational procedure proposed based on this result is demonstrated to be effective in both linear and nonlinear cases.published_or_final_versio
A Semi-analytical Model for Remote Sensing Retrieval of Suspended Sediment Concentration in the Gulf of Bohai, China
published_or_final_versio
Trends of prescribing adherence of antiplatelet agents in Hong Kong patients with acute coronary syndrome: a 10-year retrospective observational cohort study
ObjectivesThe objective of this study is to examine the temporal trend of antiplatelet prescribing pattern during index hospitalisation discharge in Hong Kong (HK) acute coronary syndrome (ACS) population.DesignThe study is a retrospective observational cohort study.SettingThe study retrieved data from electronic health record from Hospital Authority (HA), HK.ParticipantsThe study included patients aged 18 years old or above, who were admitted to seven institutions under HA with diagnosis of ACS during 2008–2017.Primary and secondary outcome measuresThe primary outcome was the frequency of antiplatelet therapy prescription at the point of index hospitalisation discharge each year during 2008–2017. Association between demographics, baseline comorbidities, procedures and antiplatelet prescription were examined as secondary outcome using multivariate logistic regression model, with commonly used antiplatelet groups selected for comparison.ResultsAmong the included 14 716 patients, 5888 (40.0%) discharged with aspirin alone, 6888 (46.8%) discharged with dual antiplatelet therapy (DAPT) with clopidogrel, and 973 (6.6%) discharged with DAPT with prasugrel/ticagrelor. Prescribing rate of aspirin alone decreased substantially from 56.8% in 2008 to 27.5% in 2017. Utilisation of DAPT with clopidogrel increased from 33.7% in 2008 to 52.7% in 2017. Use of DAPT with prasugrel/ticagrelor increased from 0.3% in 2010 to 15.3% in 2017. Compared with those prescribed with DAPT with clopidogrel, male patients (adjusted OR (aOR) 1.34, 95% CI 1.09 to 1.65), patients with non-ST-elevation myocardial infarction (aOR 2.50, 1.98 to 3.16) or ST-elevation myocardial infarction (aOR 3.26, 2.59 to 4.09), use of glycoprotein IIb/IIIa (aOR 3.03, 2.48 to 3.68) or undergoing percutaneous coronary intervention (aOR 3.85, 3.24 to 4.58) or coronary artery bypass graft (aOR 6.52, 4.63 to 9.18) during index hospitalisation, concurrent use of histamine-2 receptor antagonists (aOR 1.35, 1.10 to 1.65) or proton pump inhibitors (aOR 3.57, 2.93 to 4.36) during index hospitalisation discharge were more likely to be prescribed with DAPT with prasugrel/ticagrelor. Patients with older age (aOR 0.97, 0.96 to 0.97), diabetes (aOR 0.68, 0.52 to 0.88), chronic kidney disease (aOR 0.43, 0.22 to 0.85) or concurrent use of oral anticoagulant (aOR 0.16, 0.07 to 0.42) were more likely to received DAPT with clopidogrel.ConclusionsUse of DAPT with prasugrel/ticagrelor was suboptimal yet improving during 2008–2017 in HK patients with ACS. Considering DAPT, predictors for clopidogrel prescription, compared with prasugrel/ticagrelor, were consistent with identified risk factors of bleeding
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Self-Cleaning Glass of Photocatalytic Anatase TiO2@Carbon Nanotubes Thin Film by Polymer-Assisted Approach
Due to the good photocatalytic activity, the TiO2@CNTs thin film is highly desirable to apply to the self-cleaning glass for green intelligent building. Here, the TiO2@CNTs thin film has been successfully achieved by polymer-assisted approach of an aqueous chemical solution method. The polymer, polyethylenimine, aims to combine the Ti4+ with CNTs for film formation of TiO2@CNTs. The resultant thin film was uniform, highly transparent, and super-hydrophilic. Owing to fast electron transport and effectively hindering electron-hole recombination, the TiO2@CNTs thin film has nearly twofold photocatalytic performance than pure TiO2. The TiO2@CNTs thin films show a good application for self-cleaning glasses
Higher fungal diversity is correlated with lower CO2 emissions from dead wood in a natural forest
Wood decomposition releases almost as much CO2 to the atmosphere as does fossil-fuel combustion, so the factors regulating wood decomposition can affect global carbon cycling. We used metabarcoding to estimate the fungal species diversities of naturally colonized decomposing wood in subtropical China and, for the first time, compared them to concurrent measures of CO2 emissions. Wood hosting more diverse fungal communities emitted less CO2, with Shannon diversity explaining 26 to 44% of emissions variation. Community analysis supports a ‘pure diversity’ effect of fungi on decomposition rates and thus suggests that interference competition is an underlying mechanism. Our findings extend the results of published experiments using low-diversity, laboratory-inoculated wood to a high-diversity, natural system. We hypothesize that high levels of saprotrophic fungal biodiversity could be providing globally important ecosystem services by maintaining dead-wood habitats and by slowing the atmospheric contribution of CO2 from the world’s stock of decomposing wood. However, large-scale surveys and controlled experimental tests in natural settings will be needed to test this hypothesis
One-step hydrothermal synthesis of graphene decorated V2O5 nanobelts for enhanced electrochemical energy storage
Graphene-decorated V2O5 nanobelts (GVNBs) were synthesized via a low-temperature hydrothermal method in a single step. V2O5 nanobelts (VNBs) were formed in the presence of graphene oxide, a mild oxidant, which also enhanced the conductivity of GVNBs. From the electron energy loss spectroscopy analysis, the reduced graphene oxide (rGO) are inserted into the layered crystal structure of V2O5 nanobelts, which further confirmed the enhanced conductivity of the nanobelts. The electrochemical energy-storage capacity of GVNBs was investigated for supercapacitor applications. The specific capacitance of GVNBs was evaluated using cyclic voltammetry (CV) and charge/discharge (CD) studies. The GVNBs having V2O5-rich composite, namely, V(3)G(1) (VO/GO = 3:1), showed superior specific capacitance in comparison to the other composites (V(1)G(1) and V(1)G(3)) and the pure materials. Moreover, the V(3)G(1) composite showed excellent cyclic stability and the capacitance retention of about 82% was observed even after 5000 cycles.open
Effects of early feeding on growth velocity and overweight/obesity in a cohort of HIV unexposed South African infants and children
BACKGROUND: South Africa has the highest prevalence of overweight/obesity in Sub-Saharan Africa. Assessing the
effect of modifiable factors such as early infant feeding on growth velocity and overweight/obesity is therefore important.
This paper aimed to assess the effect of infant feeding in the transitional period (12 weeks) on 12–24 week growth
velocity amongst HIV unexposed children using WHO growth velocity standards and on the age and sex adjusted body
mass index (BMI) Z-score distribution at 2 years.
METHODS: Data were from 3 sites in South Africa participating in the PROMISE-EBF trial. We calculated growth velocity
Z-scores using the WHO growth standards and assessed feeding practices using 24-hour and 7-day recall data. We used
quantile regression to study the associations between 12 week infant feeding and 12–24 week weight velocity (WVZ) with
BMI-for-age Z-score at 2 years. We included the internal sample quantiles (70th and 90th centiles) that approximated the
reference cut-offs of +2 (corresponding to overweight) and +3 (corresponding to obesity) of the 2 year BMI-for-age Z-scores.
RESULTS: At the 2-year visit, 641 children were analysed (median age 22 months, IQR: 17–26 months). Thirty
percent were overweight while 8.7% were obese. Children not breastfed at 12 weeks had higher 12–24 week mean WVZ
and were more overweight and obese at 2 years. In the quantile regression, children not breastfed at 12 weeks had a 0.37
(95% CI 0.07, 0.66) increment in BMI-for-age Z-score at the 50th sample quantile compared to breast-fed children. This difference
in BMI-for-age Z-score increased to 0.46 (95% CI 0.18, 0.74) at the 70th quantile and 0.68 (95% CI 0.41, 0.94) at the 90th
quantile . The 12–24 week WVZ had a uniform independent
effect across the same quantiles.
CONCLUSIONS: This study demonstrates that the first 6 months of life is a critical period in the development of childhood
overweight and obesity. Interventions targeted at modifiable factors such as early infant feeding practices may reduce the
risks of rapid weight gain and subsequent childhood overweight/obesity.Scopu
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