Complex Systems Science: Dreams of Universality, Reality of Interdisciplinarity

Using a large database (~ 215 000 records) of relevant articles, we empirically study the "complex systems" field and its claims to find universal principles applying to systems in general. The study of references shared by the papers allows us to obtain a global point of view on the structure of this highly interdisciplinary field. We show that its overall coherence does not arise from a universal theory but instead from computational techniques and fruitful adaptations of the idea of self-organization to specific systems. We also find that communication between different disciplines goes through specific "trading zones", ie sub-communities that create an interface around specific tools (a DNA microchip) or concepts (a network).Comment: Journal of the American Society for Information Science and Technology (2012) 10.1002/asi.2264

Characterization of selected waste tanks from the active LLLW system

From September 1989 through January of 1990, there was a major effort to sample and analyze the Active Liquid-Low Level Waste (LLLW) tanks at ORNL which include the Melton Valley Storage Tanks (MVST) and the Bethel Valley Evaporator Service Tanks (BVEST). The purpose of this report is to summarize additional analytical data collected from some of the active waste tanks from November 1993 through February 1996. The analytical data for this report was collected for several unrelated projects which had different data requirements. The overall analyte list was similar for these projects and the level of quality assurance was the same for all work reported. the new data includes isotopic ratios for uranium and plutonium and an evaluation of the denature ratios to address criticality concerns. Also, radionuclides not previously measured in these waste tanks, including 99Tc and 237Np, are provided in this report

Stochastic resonance in pattern recognition by a holographic neuron model

The recognition rate of holographic neural synapses, performing a pattern recognition task, is significantly higher when applied to natural, rather than artificial, images. This shortcoming of artificial images can be largely compensated for, if noise is added to the input pattern. The effect is the result of a trade-off between optimal representation of the stimulus (for which noise is favorable) and keeping as much as possible of the stimulus-specific information (for which noise is detrimental). The observed mechanism may play a prominent role for simple biological sensors

CYP-13A12 of the nematode Caenorhabditis elegans is a PUFA-epoxygenase involved in behavioural response to reoxygenation

A specific behavioural response of Caenorhabditis elegans, the rapid increase of locomotion in response to anoxia/reoxygenation called the O2-ON response, has been used to model key aspects of ischaemia/reperfusion injury. A genetic suppressor screen demonstrated a direct causal role of CYP (cytochrome P450)-13A12 in this response and suggested that CYP-eicosanoids, which in mammals influence the contractility of cardiomyocytes and vascular smooth muscle cells, might function in C. elegans as specific regulators of the body muscle cell activity. In the present study we show that co-expression of CYP-13A12 with the NADPH-CYP-reductase EMB-8 in insect cells resulted in the reconstitution of an active microsomal mono-oxygenase system that metabolized EPA (eicosapentaenoic acid) and also AA (arachidonic acid) to specific sets of regioisomeric epoxy and hydroxy derivatives. The main products included 17,18-EEQ (17,18-epoxyeicosatetraenoic acid) from EPA and 14,15-EET (14,15-epoxyeicosatrienoic acid) from AA. Locomotion assays showed that the defective O2-ON response of C20-PUFA (polyunsaturated fatty acid)-deficient, Δ-12 and Δ-6 fatty acid desaturase mutants (fat-2 and fat-3 respectively) can be restored by feeding the nematodes AA or EPA, but not ETYA (eicosatetraynoic acid), a non-metabolizable AA analogue. Short-term incubation with 17,18-EEQ was sufficient to rescue the impaired locomotion of the fat-3 strain. The endogenous level of free 17,18-EEQ declined during anoxia and was rapidly restored in response to reoxygenation. On the basis of these results, we suggest that CYP-dependent eicosanoids such as 17,18-EEQ function as signalling molecules in the regulation of the O2-ON response in C. elegans. Remarkably, the exogenously administered 17,18-EEQ increased the locomotion activity under normoxic conditions and was effective not only with C20-PUFA-deficient mutants, but to a lesser extent also with wild-type worms

Metastable Random Field Ising model with exchange enhancement: a simple model for Exchange Bias

We present a simple model that allows hysteresis loops with exchange bias to be reproduced. The model is a modification of the T=0 random field Ising model driven by an external field and with synchronous local relaxation dynamics. The main novelty of the model is that a certain fraction f of the exchange constants between neighbouring spins is enhanced to a very large value J_E. The model allows the dependence of the exchange bias and other properties of the hysteresis loops to be analyzed as a function of the parameters of the model: the fraction f of enhanced bonds, the amount of the enhancement J_E and the amount of disorder which is controlled by the width sigma of the Gaussian distribution of the random fields.Comment: 8 pages, 11 figure

Comment on "Resolving the 180-deg Ambiguity in Solar Vector Magnetic Field Data: Evaluating the Effects of Noise, Spatial Resolution, and Method Assumptions"

In a recent paper, Leka at al. (Solar Phys. 260, 83, 2009)constructed a synthetic vector magnetogram representing a three-dimensional magnetic structure defined only within a fraction of an arcsec in height. They rebinned the magnetogram to simulate conditions of limited spatial resolution and then compared the results of various azimuth disambiguation methods on the resampled data. Methods relying on the physical calculation of potential and/or non-potential magnetic fields failed in nearly the same, extended parts of the field of view and Leka et al. (2009) attributed these failures to the limited spatial resolution. This study shows that the failure of these methods is not due to the limited spatial resolution but due to the narrowly defined test data. Such narrow magnetic structures are not realistic in the real Sun. Physics-based disambiguation methods, adapted for solar magnetic fields extending to infinity, are not designed to handle such data; hence, they could only fail this test. I demonstrate how an appropriate limited-resolution disambiguation test can be performed by constructing a synthetic vector magnetogram very similar to that of Leka et al. (2009) but representing a structure defined in the semi-infinite space above the solar photosphere. For this magnetogram I find that even a simple potential-field disambiguation method manages to resolve the ambiguity very successfully, regardless of limited spatial resolution. Therefore, despite the conclusions of Leka et al. (2009), a proper limited-spatial-resolution test of azimuth disambiguation methods is yet to be performed in order to identify the best ideas and algorithms.Comment: Solar Physics, in press (19 pp., 5 figures, 2 tables

Enterotypes of the human gut mycobiome

BACKGROUND: The fungal component of the human gut microbiome, also known as the mycobiome, plays a vital role in intestinal ecology and human health. However, the overall structure of the gut mycobiome as well as the inter-individual variations in fungal composition remains largely unknown. In this study, we collected a total of 3363 fungal sequencing samples from 16 cohorts across three continents, including 572 newly profiled samples from China. RESULTS: We identify and characterize four mycobiome enterotypes using ITS profiling of 3363 samples from 16 cohorts. These enterotypes exhibit stability across populations and geographical locations and significant correlation with bacterial enterotypes. Particularly, we notice that fungal enterotypes have a strong age preference, where the enterotype dominated by Candida (i.e., Can_type enterotype) is enriched in the elderly population and confers an increased risk of multiple diseases associated with a compromised intestinal barrier. In addition, bidirectional mediation analysis reveals that the fungi-contributed aerobic respiration pathway associated with the Can_type enterotype might mediate the association between the compromised intestinal barrier and aging. CONCLUSIONS: We show that the human gut mycobiome has stable compositional patterns across individuals and significantly correlates with multiple host factors, such as diseases and host age. Video Abstract

Dynamical stability of infinite homogeneous self-gravitating systems: application of the Nyquist method

We complete classical investigations concerning the dynamical stability of an infinite homogeneous gaseous medium described by the Euler-Poisson system or an infinite homogeneous stellar system described by the Vlasov-Poisson system (Jeans problem). To determine the stability of an infinite homogeneous stellar system with respect to a perturbation of wavenumber k, we apply the Nyquist method. We first consider the case of single-humped distributions and show that, for infinite homogeneous systems, the onset of instability is the same in a stellar system and in the corresponding barotropic gas, contrary to the case of inhomogeneous systems. We show that this result is true for any symmetric single-humped velocity distribution, not only for the Maxwellian. If we specialize on isothermal and polytropic distributions, analytical expressions for the growth rate, damping rate and pulsation period of the perturbation can be given. Then, we consider the Vlasov stability of symmetric and asymmetric double-humped distributions (two-stream stellar systems) and determine the stability diagrams depending on the degree of asymmetry. We compare these results with the Euler stability of two self-gravitating gaseous streams. Finally, we determine the corresponding stability diagrams in the case of plasmas and compare the results with self-gravitating systems

Exact results on decoherence and entanglement in a system of N driven atoms and a dissipative cavity mode

We solve the dynamics of an open quantum system where N strongly driven two-level atoms are equally coupled on resonance to a dissipative cavity mode. Analytical results are derived on decoherence, entanglement, purity, atomic correlations and cavity field mean photon number. We predict decoherence-free subspaces for the whole system and the N-qubit subsystem, the monitoring of quantum coherence and purity decay by atomic populations measurements, the conditional generation of atomic multi-partite entangled states and of cavity cat-like states. We show that the dynamics of atoms prepared in states invariant under permutation of any two components remains restricted within the subspace spanned by the completely symmetric Dicke states. We discuss examples and applications in the cases N=3,4.Comment: 7 pages, 4 figures, accepted in EPJ

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results