Multiple glass transitions in vapor-deposited orientational glasses of the most fragile plastic crystal Freon 113

We investigate by fast-scanning nanocalorimetry the formation of Freon 113 films from the vapor phase at deposition temperatures ranging from 50 to 120 K, that is, spanning above and below the transition temperature of the glassy crystal to the plastic crystal (Tgc = 72 K). Analysis of the heat capacity curves indicates that vapor deposition at T < Tgc of the highly fragile Freon 113 yields structural and orientational glasses in the as-deposited state depending on the temperature range of deposition. Interestingly, growing above Tgc produces plastic crystals with a conformational ratio C1/Cs that changes with Tdep above and below 110–120 K, the temperature at which previous works have identified the arrest of the transformations between the C1 and Cs conformers.Peer ReviewedPostprint (author's final draft

The emergence, impact, and evolution of human metapneumovirus variants from 2014 to 2021 in Spain

Epidemiology; Human metapneumovirus; Whole-genome sequencingEpidemiologia; Metapneumovirus humà; Seqüenciació del genoma completEpidemiología; Metapneumovirus humano; Secuenciación del genoma completoBackground Human metapneumovirus (HMPV) is an important aetiologic agent of respiratory tract infection (RTI). This study aimed to describe the prevalence, genetic diversity, and evolutionary dynamics of HMPV. Methods Laboratory-confirmed HMPV were characterised based on partial-coding G gene sequences with MEGA.v6.0. WGS was performed with Illumina, and evolutionary analyses with Datamonkey and Nextstrain. Results HMPV prevalence was 2.5%, peaking in February-April and with an alternation in the predominance of HMPV-A and –B until the emergence of SARS-CoV-2, not circulating until summer and autumn-winter 2021, with a higher prevalence and with the almost only circulation of A2c111dup. G and SH proteins were the most variable, and 70% of F protein was under negative selection. Mutation rate of HMPV genome was 6.95 × 10-4 substitutions/site/year. Conclusion HMPV showed a significant morbidity until the emergence of SARS-CoV-2 pandemic in 2020, not circulating again until summer and autumn 2021, with a higher prevalence and with almost the only circulation of A2c111dup, probably due to a more efficient immune evasion mechanism. The F protein showed a very conserved nature, supporting the need for steric shielding. The tMRCA showed a recent emergence of the A2c variants carrying duplications, supporting the importance of virological surveillance.This study was supported by the European Regional Development Fund (ERDF) "A way to achieve Europe", Spanish Network for Research in Infectious Diseases [REIPI RD16/0016/0003], and supported by the Health Research Fund, Spanish Ministry of Economy and Competitiveness [Grant FIS PI18/00685]

Responses of coastal osmotrophic planktonic communities to simulated events of turbulence and nutrient load throughout a year

A year-long series of monthly experiments with laboratory enclosures were conducted with water from Blanes Bay (NW Mediterranean) to analyse the change in the short-time response of the osmotrophic planktonic community to simulated turbulence and nutrient input events. Both experimental factors triggered a relative increase of biomass in the enclosures, in terms of chlorophyll a, bacteria and particulate organic matter. Ratios of particulate organic nitrogen to phosphorus became lower in the water than in the sediment, although turbulence partially smoothed out this difference. Initial physico-chemical conditions significantly influenced the short-time responses to experimental forcing. The response to turbulence, in terms of chlorophyll a, was maximum in spring. The response to nutrient enrichment was found to be seasonal, and was correlated with photoperiod and temperature, and also in situ nitrate and silicate concentrations and Secchi depth, which are proxies of recent inputs of nutrients resulting from episodes of resuspension and river discharge. This study shows robust qualitative regularities in the response of the osmotrophic planktonic community to episodes of turbulence and nutrient enrichment, with quantitative variability throughout the year, depending mostly on the recent record of hydrodynamic forcing

Famílies botàniques de plantes medicinals

Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia, Assignatura: Botànica Farmacèutica, Curs: 2013-2014, Coordinadors: Joan Simon, Cèsar Blanché i Maria Bosch.Els materials que aquí es presenten són els recull de 175 treballs d’una família botànica d’interès medicinal realitzats de manera individual. Els treballs han estat realitzat per la totalitat dels estudiants dels grups M-2 i M-3 de l’assignatura Botànica Farmacèutica durant els mesos d’abril i maig del curs 2013-14. Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pel professor de l’assignatura i revisats i finalment co-avaluats entre els propis estudiants. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica

Bones pràctiques en atenció compartida: recomanacions per a una gestió òptima dels PIIC

Bones pràctiques; Presa decisions; Plans d’intervenció individualitzats i compartitsBuenas prácticas; Toma de decisiones; Planes de intervención individualizados i compartidosGood practices; Decision making; Individualized and shared intervention plansAquest document és un instrument per a professionals de l'atenció sanitària per posar al dia els criteris de bon ús dels PIIC respecte a la revisió que es va publicar l’abril de 2015

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Search for stop and higgsino production using diphoton Higgs boson decays

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top-quark (stop) and the Higgs boson (higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-quark jets. In 19.7 inverse femtobarns of proton-proton collision data at sqrt(s) = 8 TeV, recorded in the CMS experiment, no evidence of a signal is found and lower limits at the 95% confidence level are set, excluding the stop mass below 360 to 410 GeV, depending on the higgsino mass

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI