1,476 research outputs found

    Simulação de Organizações Internacionais para alunos do ensino médio (SIEM)

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    Anais do 35º Seminário de Extensão Universitária da Região Sul - Área temática: EducaçãoO SiEM pretende oferecer aos alunos de ensino médio de Santa Catarina a oportunidade de debater assuntos conflituosos da agenda internacional, através de simulações das organizações internacionais. Assim, busca-se estimular no jovem estudante a capacidade de compreensão dos acontecimentos internacionais, a cultura da tolerância e a ampliação de sua consciência social. O projeto vem sendo desenvolvido com êxito e sucesso desde 2011 e já está em sua 7 a ediçã

    Analyzing public hearings in environmental licensing: who are and what say the participants about sugarcane mill projects

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    Public hearings are the primary mechanism for public participation in Brazilian environmental licensing. Created to inform and listen to the public, the hearings are criticized for their low influence on decision-making, resulting, among other reasons, from its late occurrence in the licensing process. Seeking to explore the theme in a sector where public participation is not usually researched, this paper presents an analysis of 25 public hearings about the process of environmental licensing of sugarcane mills in the state of São Paulo, Brazil. Most of the 62 participants are citizens, followed by representatives of local governments and representatives of civil society organizations. Regarding the characteristics of speeches, 50.9% were statements/comments, 15.2% highlighted positive aspects of the project/company, 11.2% were questions, 9.4% highlighted negative aspects, 5.4% were suggestions; 6.5% were for endorsing the project, and 1.4% for opposing. As for themes, employment and income generation and the company’s reputation are the most frequent, highlighted mainly for its positive aspects. These themes differ from those discussed in the literature as relevant for sugarcane expansion impact, showing a marked difference between citizens’ and scientists’ perspectives about its social and environmental consequences.Audiências públicas são o principal mecanismo para participação em processos de licenciamento ambiental no Brasil. Criadas para informar e ouvir o público, as audiências são criticadas por sua baixa capacidade de influenciar decisões, atribuída, entre outros fatores, à realização tardia no processo de licenciamento. Buscando explorar essa temática em um setor no qual a participação pública é pouco estudada, foi realizada análise documental de 25 audiências públicas de processos de licenciamento ambiental para implantação ou ampliação de usinas de cana-de-açúcar em São Paulo. A maioria dos 62 participantes que fizeram uso da palavra são cidadãos, seguidos de representantes do Poder Executivo e de representantes de entidades da sociedade civil. Quanto às características das falas, 50,9% foram afirmações/comentários, 15,2% ressaltaram aspectos positivos do projeto/empresa, 11,2% apresentaram questionamentos, 9,4% destacaram aspectos negativos, 5,4% apresentaram sugestões, 6,5% foram de endosso ao projeto e 1,4% de oposição. Quanto aos temas abordados, geração de emprego e renda e a reputação da empresa são os mais frequentes, destacados majoritariamente em seus aspectos positivos. Estes temas diferem daqueles destacados na literatura como relevantes para discutir os impactos da expansão da cana-de-açúcar, mostrando a diferença entre a apreciação popular e a técnico-científica dos impactos socioambientais

    Ten important questions/issues for ethnobotanical research

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    Unidad de excelencia María de Maeztu MdM-2015-0552For at least 30 years researchers have called for a deeper reflection on the paths we desire for ethnobotanical research. Although the discipline of ethnobotany is growing, as measured by the number of publications in the area, there is still work to be done regarding the homogeneity of theoretical and methodological approaches and the implications of ethnobotanical research findings for society as a whole. In this article we present 10 questions/issues that we believe can guide the research and actions of ethnobotanists for the coming years

    Ten important questions/issues for ethnobotanical research

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    For at least 30 years researchers have called for a deeper reflection on the paths we desire for ethnobotanical research. Although the discipline of ethnobotany is growing, as measured by the number of publications in the area, there is still work to be done regarding the homogeneity of theoretical and methodological approaches and the implications of ethnobotanical research findings for society as a whole. In this article we present 10 questions/issues that we believe can guide the research and actions of ethnobotanists for the coming years.Laboratorio de Etnobotánica y Botánica Aplicad

    Clinical correlates and prognostic impact of neurologic disorders in Takotsubo syndrome

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    © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Cardiac alterations are frequently observed after acute neurological disorders. Takotsubo syndrome (TTS) represents an acute heart failure syndrome and is increasingly recognized as part of the spectrum of cardiac complications observed after neurological disorders. A systematic investigation of TTS patients with neurological disorders has not been conducted yet. The aim of the study was to expand insights regarding neurological disease entities triggering TTS and to investigate the clinical profile and outcomes of TTS patients after primary neurological disorders. The International Takotsubo Registry is an observational multicenter collaborative effort of 45 centers in 14 countries (ClinicalTrials.gov, identifier NCT01947621). All patients in the registry fulfilled International Takotsubo Diagnostic Criteria. For the present study, patients were included if complete information on acute neurological disorders were available. 2402 patients in whom complete information on acute neurological status were available were analyzed. In 161 patients (6.7%) an acute neurological disorder was identified as the preceding triggering factor. The most common neurological disorders were seizures, intracranial hemorrhage, and ischemic stroke. Time from neurological symptoms to TTS diagnosis was ≤ 2 days in 87.3% of cases. TTS patients with neurological disorders were younger, had a lower female predominance, fewer cardiac symptoms, lower left ventricular ejection fraction, and higher levels of cardiac biomarkers. TTS patients with neurological disorders had a 3.2-fold increased odds of in-hospital mortality compared to TTS patients without neurological disorders. In this large-scale study, 1 out of 15 TTS patients had an acute neurological condition as the underlying triggering factor. Our data emphasize that a wide spectrum of neurological diseases ranging from benign to life-threatening encompass TTS. The high rates of adverse events highlight the need for clinical awareness.The International Takotsubo Registry was supported by the Biss Davies Charitable Trust. Dr. Scheitz has been supported by the Corona Foundation. Dr. Templin has been supported by the H.H. Sheikh Khalifa bin Hamad Al-Thani Research Programme and the Swiss Heart Foundation.info:eu-repo/semantics/publishedVersio

    Pervasive gaps in Amazonian ecological research

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    Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

    Pervasive gaps in Amazonian ecological research

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    Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial

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    Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

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    Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

    Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

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    Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio
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