316 research outputs found
Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients.
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Interrogating colorectal cancer metastasis to liver: a search for clinically viable compounds and mechanistic insights in colorectal cancer Patient Derived Organoids
- Author
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Approximately 20-50% of patients presenting with localized colorectal cancer progress to stage IV metastatic disease (mCRC) following initial treatment and this is a major prognostic determinant. Here, we have interrogated a heterogeneous set of primary colorectal cancer (CRC), liver CRC metastases and adjacent liver tissue to identify molecular determinants of the colon to liver spreading. Screening Food and Drug Administration (FDA) approved drugs for their ability to interfere with an identified colon to liver metastasis signature may help filling an unmet therapeutic need
Direct photon production with effective field theory
- Author
- A Ferroglia
- A Ferroglia
- A Hornig
- A Idilbi
- A Idilbi
- A Vogt
- AD Martin
- AV Manohar
- C Lee
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bauer
- CW Bauer
- D Appell
- DE Kaplan
- E Gardi
- E Laenen
- F Fazio De
- G Sterman
- J-y Chiu
- J-y Chiu
- J-y Chiu
- LE Gordon
- M Beneke
- M Beneke
- M Czakon
- Matthew D. Schwartz
- MD Schwartz
- N Kidonakis
- N Kidonakis
- P Aurenche
- P Aurenche
- P-y Chen
- PB Arnold
- RJ Hill
- S Catani
- S Catani
- S Catani
- S Catani
- S Catani
- S Catani
- S Catani
- S Fleming
- S Fleming
- S Fleming
- S Fleming
- S Moch
- SM Aybat
- SM Aybat
- T Aaltonen
- T Becher
- T Becher
- T Becher
- T Becher
- T Becher
- T Becher
- T Becher
- T Becher
- T Ritbergen van
- Thomas Becher
- V Ahrens
- V Ahrens
- VM Abazov
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2010
- Field of study
The production of hard photons in hadronic collisions is studied using
Soft-Collinear Effective Theory (SCET). This is the first application of SCET
to a physical, observable cross section involving energetic partons in more
than two directions. A factorization formula is derived which involves a
non-trivial interplay of the angular dependence in the hard and soft functions,
both quark and gluon jet functions, and multiple partonic channels. The
relevant hard, jet and soft functions are computed to one loop and their
anomalous dimensions are determined to three loops. The final resummed
inclusive direct photon distribution is valid to next-to-next-to-leading
logarithmic order (NNLL), one order beyond previous work. The result is
improved by including non-logarithmic terms and photon isolation cuts through
matching, and compared to Tevatron data and to fixed order results at the
Tevatron and the LHC. The resummed cross section has a significantly smaller
theoretical uncertainty than the next-to-leading fixed-order result,
particularly at high transverse momentum.Comment: 42 pages, 9 figures; v2: references added, minor changes; v3: typos;
v4: typos, corrections in (16), (47), (72
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
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- Ammosov VV
- Amorim A
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- Amram N
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- Anders G
- Anderson KJ
- Andreazza A
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- Anh TV
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- Zhemchugov A
- Zheng S
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
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- Zhemchugov A
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Search for R-parity-violating supersymmetry in events with four or more leptons in sqrt(s) =7 TeV pp collisions with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Khalek SA
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Acharya BS
- Adamczyk L
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- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Agustoni M
- Aharrouche M
- Ahlen SP
- Ahles F
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- Akesson TPA
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- Akimov AV
- Alam MS
- Alam MA
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BMM
- Allport PP
- Allwood-Spiers SE
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- Yanush S
- Yao L
- Yao Y
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- Ye J
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- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
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- Zaidan R
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- Zeitnitz C
- Zeman M
- Zemla A
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- Zenin O
- Zenis T
- Zinonos Z
- Zerwas D
- della Porta GZ
- Zhang D
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- Zhao Z
- Zhemchugov A
- Zhong J
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- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Collaboration ATLAS
- Publication venue
- Springer Verlag
- Publication date
- 01/01/2008
- Field of study
A search for new phenomena in final states with four or more leptons (electrons or muons) is presented. The analysis is based on 4.7 fb−1 of s=7TeV proton-proton collisions delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in two signal regions: one that requires moderate values of missing transverse momentum and another that requires large effective mass. The results are interpreted in a simplified model of R-parity-violating supersymmetry in which a 95% CL exclusion region is set for charged wino masses up to 540 GeV. In an R-parity-violating MSUGRA/CMSSM model, values of m 1/2 up to 820 GeV are excluded for 10 < tan β < 40
Search for high-mass resonances decaying to dilepton final states in pp collisions at s√=7 TeV with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
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- Acharya BS
- Adamczyk L
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- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albert J
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- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
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- Alexandre G
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- Aliev M
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- Allbrooke BMM
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- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang UK
- Yang Y
- Yang Z
- Yanush S
- Yao L
- Yao Y
- Yasu Y
- Ye J
- Ye S
- Yildiz HD
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenis T
- Zerwas D
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- Springer
- Publication date
- 23/11/2012
- Field of study
The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to an electron-positron pair or a muon-antimuon pair. The search is sensitive to heavy neutral Z′ gauge bosons, Randall-Sundrum gravitons, Z * bosons, techni-mesons, Kaluza-Klein Z/γ bosons, and bosons predicted by Torsion models. Results are presented based on an analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fb−1 in the e + e − channel and 5.0 fb−1 in the μ + μ −channel. A Z ′ boson with Standard Model-like couplings is excluded at 95 % confidence level for masses below 2.22 TeV. A Randall-Sundrum graviton with coupling k/MPl=0.1 is excluded at 95 % confidence level for masses below 2.16 TeV. Limits on the other models are also presented, including Technicolor and Minimal Z′ Models
Syntenic relationships between cucumber (Cucumis sativus L.) and melon (C. melo L.) chromosomes as revealed by comparative genetic mapping
- Author
- A Dijkhuizen
- A Paterson
- AG Ghebretinsae
- AG Ghebretinsae
- AJ Monforte
- AK Singh
- B Keller
- C Alonso Blanco
- C Liu
- C Nieto
- C Perin
- C Ramachandran
- Dawei Li
- DH Koo
- DH Koo
- DH Koo
- E Dirlewanger
- F Luan
- Feishi Luan
- FN Wu
- G Fazio
- H Miao
- H Schaefer
- H Tang
- HB Liu
- HE Cuevas
- HE Cuevas
- HH Yan
- HM Munger
- HT Phan
- Hugo E Cuevas
- I Fernandez-Silva
- J Mudge
- J Wang
- Jack E Staub
- JDF Meyer
- JE Zalapa
- JF Chen
- JF Chen
- JF Chen
- JH Kirkbride
- JL Weber
- Jordi Garcia-Mas
- Juan Zalapa
- K Arumanagathan
- KM Paris
- KR Ayyngar
- L Silberstein
- LD Knerr
- Luming Yang
- M Chen
- M Park
- M Wierdl
- MD Gale
- MG Murray
- MJ Gonzalo
- MW Bonierbale
- N Chiba
- N Fukino
- N Fukino
- N Katzir
- NO Nilsson
- P Kalo
- P Sebastian
- PE McClean
- PF Cavagnaro
- PS Ritschel
- Q Kong
- Q Kong
- R Harel-Beja
- RN Trivedi
- RW Robinson
- S Ahn
- S Huang
- S Jung
- SB Cannon
- SD Tanksley
- SL Neuhausen
- SM Chung
- SS Renner
- T Debener
- TW Whitaker
- TW Whittaker
- Umesh Reddy
- V Meglic
- VM González
- VM González
- W Deleu
- W Ramakrishna
- WC Kennard
- X Qi
- Xiaoming He
- Y Danin-Poleg
- Y Danin-Poleg
- Y Park
- Y Ren
- Y Weng
- Y Weng
- YH Han
- YH Han
- YH Han
- Yiqun Weng
- Yuhong Li
- Zhenhui Gong
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>Cucumber, <it>Cucumis sativus </it>L. (2n = 2 × = 14) and melon, <it>C. melo </it>L. (2n = 2 × = 24) are two important vegetable species in the genus <it>Cucumis </it>(family Cucurbitaceae). Both species have an Asian origin that diverged approximately nine million years ago. Cucumber is believed to have evolved from melon through chromosome fusion, but the details of this process are largely unknown. In this study, comparative genetic mapping between cucumber and melon was conducted to examine syntenic relationships of their chromosomes.</p> <p>Results</p> <p>Using two melon mapping populations, 154 and 127 cucumber SSR markers were added onto previously reported F<sub>2</sub>- and RIL-based genetic maps, respectively. A consensus melon linkage map was developed through map integration, which contained 401 co-dominant markers in 12 linkage groups including 199 markers derived from the cucumber genome. Syntenic relationships between melon and cucumber chromosomes were inferred based on associations between markers on the consensus melon map and cucumber draft genome scaffolds. It was determined that cucumber Chromosome 7 was syntenic to melon Chromosome I. Cucumber Chromosomes 2 and 6 each contained genomic regions that were syntenic with melon chromosomes III+V+XI and III+VIII+XI, respectively. Likewise, cucumber Chromosomes 1, 3, 4, and 5 each was syntenic with genomic regions of two melon chromosomes previously designated as II+XII, IV+VI, VII+VIII, and IX+X, respectively. However, the marker orders in several syntenic blocks on these consensus linkage maps were not co-linear suggesting that more complicated structural changes beyond simple chromosome fusion events have occurred during the evolution of cucumber.</p> <p>Conclusions</p> <p>Comparative mapping conducted herein supported the hypothesis that cucumber chromosomes may be the result of chromosome fusion from a 24-chromosome progenitor species. Except for a possible inversion, cucumber Chromosome 7 has largely remained intact in the past nine million years since its divergence from melon. Meanwhile, many structural changes may have occurred during the evolution of the remaining six cucumber chromosomes. Further characterization of the genomic nature of <it>Cucumis </it>species closely related to cucumber and melon might provide a better understanding of the evolutionary history leading to modern cucumber.</p
Recommended from our members
The Belle II physics book
- Author
- Altmannshofer W
- Beaujean F
- Bell G
- Beneke M
- Bigi II
- Bishara F
- Blanke M
- Bobeth C
- Bona M
- Brambilla N
- Braun VM
- Brod J
- Buras AJ
- Cheng HY
- Chiang CW
- Ciuchini M
- Colangelo G
- Crivellin A
- Czyz H
- Datta A
- De Fazio F
- Deppisch T
- Dolan MJ
- Evans J
- Fajfer S
- Feldmann T
- Godfrey S
- Gronau M
- Grossman Y
- Guo FK
- Haisch U
- Hanhart C
- Hashimoto S
- Hirose S
- Hisano J
- Hofer L
- Hoferichter M
- Hou WS
- Huber T
- Hurth T
- Jaeger S
- Jahn S
- Jamin M
- Jones J
- Jung M
- Kagan AL
- Kahlhoefer F
- Kamenik JF
- Kaneko T
- Kiyo Y
- Kokulu A
- Kosnik N
- Kou E
- Kronfeld AS
- Ligeti Z
- Logan H
- Lu CD
- Lubicz V
- Mahmoudi F
- Maltman K
- Mishima S
- Misiak M
- Moats K
- Moussallam B
- Nefediev A
- Nierste U
- Nomura D
- Offen N
- Olsen SL
- Passemar E
- Paul A
- Paz G
- Petrov AA
- Pich A
- Polosa AD
- Pradler J
- Prelovsek S
- Procura M
- Ricciardi G
- Robinson DJ
- Roig P
- Rosiek J
- Schacht S
- Schmidt-Hoberg K
- Schwichtenberg J
- Sharpe SR
- Shigemitsu J
- Shih D
- Shimizu N
- Shimizu Y
- Silvestrini L
- Simula S
- Smith C
- Stoffer P
- Straub D
- Tackmann FJ
- Tanaka M
- Tayduganov A
- Tetlalmatzi-Xolocotzi G
- Urquijo P
- Publication venue
- eScholarship, University of California
- Publication date
- 01/12/2019
- Field of study
The Belle II detector will provide a major step forward in precision heavy flavor physics, quarkonium and exotic states, searches for dark sectors, and many other areas. The sensitivity to a large number of key observables can be improved by about an order of magnitude compared to the current measurements, and up to two orders in very clean search measurements. This increase in statistical precision arises not only due to the increased luminosity, but also from improved detector efficiency and precision for many channels. Many of the most interesting observables tend to have very small theoretical uncertainties that will therefore not limit the physics reach. This book has presented many new ideas for measurements, both to elucidate the nature of current anomalies seen in flavor, and to search for new phenomena in a plethora of observables that will become accessible with the Belle II dataset. The simulation used for the studiesinthis book was state ofthe artat the time, though weare learning a lot more about the experiment during the commissioning period. The detector is in operation, and working spectacularly well
Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s=7 TeV pp collisions with the ATLAS detector
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- Aad G
- Ab FR
- Abajyan T
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid US
- Abramowicz H
- Abreu H
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Agustoni M
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogan T
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BMM
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso F
- Altheimer A
- Alviggi MG
- Amako K
- Amelung C
- Ammosov VV
- Amorim A
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Anger R
- Angerami A
- Anghinolfi F
- Anh TV
- Anisenkov A
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Arfaoui S
- Arguin JF
- Arik E
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- Armadans RC
- Armbruster AJ
- Arnaez O
- Arnal V
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Asfandiyarov R
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astbury A
- Atkinson M
- Aubert B
- Auge E
- Augsten K
- Aurousseau M
- Avolio G
- Avramidou R
- Axen D
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
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- Bachas K
- Backes M
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- Badescu E
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- Bahinipati S
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker MD
- Baker OK
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- Banfi D
- Bangert A
- Bansal V
- Bansil HS
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- Battaglia A
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- Bell WH
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb(-1) of root s = 7 TeV proton-proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results. (C) 2012 CERN. Published by Elsevier B.V. All rights reserved
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